-
1
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
Fire A, Xu S, Montgomery MK, et al. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998; 391: 806-11.
-
(1998)
Nature
, vol.391
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
-
2
-
-
41849131453
-
RNA and transcriptional modulation of gene expression
-
Hawkins PG, Morris KV. RNA and transcriptional modulation of gene expression. Cell Cycle 2008; 7: 602-7.
-
(2008)
Cell Cycle
, vol.7
, pp. 602-607
-
-
Hawkins, P.G.1
Morris, K.V.2
-
3
-
-
39749110083
-
Small non-coding RNAs in animal development
-
Stefani G, Slack FJ. Small non-coding RNAs in animal development. Nat Rev Mol Cell Biol 2008; 9: 219-30.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 219-230
-
-
Stefani, G.1
Slack, F.J.2
-
4
-
-
0141843656
-
The nuclear RNase III Drosha initiates microRNA processing
-
Lee Y, Ahn C, Han J, et al. The nuclear RNase III Drosha initiates microRNA processing. Nature 2003; 425: 415-9.
-
(2003)
Nature
, vol.425
, pp. 415-419
-
-
Lee, Y.1
Ahn, C.2
Han, J.3
-
5
-
-
9344235449
-
Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs
-
Cai X, Hagedorn CH, Cullen BR. Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs. RNA 2004; 10: 1957-66.
-
(2004)
RNA
, vol.10
, pp. 1957-1966
-
-
Cai, X.1
Hagedorn, C.H.2
Cullen, B.R.3
-
6
-
-
9144224451
-
Processing of primary microRNAs by the microprocessor complex
-
Denli AM, Tops BB, Plasterk RH, et al. Processing of primary microRNAs by the microprocessor complex. Nature 2004; 432: 231-5.
-
(2004)
Nature
, vol.432
, pp. 231-235
-
-
Denli, A.M.1
Tops, B.B.2
Plasterk, R.H.3
-
7
-
-
51349103700
-
Primary microRNA transcripts are processed co-transcriptionally
-
Morlando M, Ballarino M, Gromak N, et al. Primary microRNA transcripts are processed co-transcriptionally. Nat Struct Mol Biol 2008; 15: 902-9.
-
(2008)
Nat Struct Mol Biol
, vol.15
, pp. 902-909
-
-
Morlando, M.1
Ballarino, M.2
Gromak, N.3
-
8
-
-
33846945735
-
Processing of intronic microRNAs
-
Kim YK, Kim VN. Processing of intronic microRNAs. Embo J 2007; 26: 775-83.
-
(2007)
Embo J
, vol.26
, pp. 775-783
-
-
Kim, Y.K.1
Kim, V.N.2
-
9
-
-
34447107760
-
The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila
-
Okamura K, Hagen JW, Duan H, et al. The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila. Cell 2007; 130: 89-100.
-
(2007)
Cell
, vol.130
, pp. 89-100
-
-
Okamura, K.1
Hagen, J.W.2
Duan, H.3
-
10
-
-
34447097693
-
Intronic microRNA precursors that bypass Drosha processing
-
Ruby JG, Jan CH, Bartel DP. Intronic microRNA precursors that bypass Drosha processing. Nature 2007; 448: 83-6.
-
(2007)
Nature
, vol.448
, pp. 83-86
-
-
Ruby, J.G.1
Jan, C.H.2
Bartel, D.P.3
-
11
-
-
0347361541
-
Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
-
Yi R, Qin Y, Macara IG, et al. Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev 2003; 17: 3011-6.
-
(2003)
Genes Dev
, vol.17
, pp. 3011-3016
-
-
Yi, R.1
Qin, Y.2
Macara, I.G.3
-
12
-
-
0347988235
-
Nuclear export of microRNA precursors
-
Lund E, Guttinger S, Calado A, et al. Nuclear export of microRNA precursors. Science 2004; 303: 95-8.
-
(2004)
Science
, vol.303
, pp. 95-98
-
-
Lund, E.1
Guttinger, S.2
Calado, A.3
-
13
-
-
0035905766
-
Role for a bidentate ribonuclease in the initiation step of RNA interference
-
Bernstein E, Caudy AA, Hammond SM, et al. Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 2001; 409: 363-6.
-
(2001)
Nature
, vol.409
, pp. 363-366
-
-
Bernstein, E.1
Caudy, A.A.2
Hammond, S.M.3
-
14
-
-
0035800521
-
A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA
-
Hutvagner G, McLachlan J, Pasquinelli AE, et al. A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science 2001; 293: 834-8.
-
(2001)
Science
, vol.293
, pp. 834-838
-
-
Hutvagner, G.1
McLachlan, J.2
Pasquinelli, A.E.3
-
15
-
-
23644433363
-
TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing
-
Chendrimada TP, Gregory RI, Kumaraswamy E, et al. TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing. Nature 2005; 436: 740-4.
-
(2005)
Nature
, vol.436
, pp. 740-744
-
-
Chendrimada, T.P.1
Gregory, R.I.2
Kumaraswamy, E.3
-
16
-
-
4444368187
-
Argonaute2 is the catalytic engine of mammalian RNAi
-
Liu J, Carmell MA, Rivas FV, et al. Argonaute2 is the catalytic engine of mammalian RNAi. Science 2004; 305: 1437-41.
-
(2004)
Science
, vol.305
, pp. 1437-1441
-
-
Liu, J.1
Carmell, M.A.2
Rivas, F.V.3
-
17
-
-
38649111931
-
In vitro reconstitution of the human RISC-loading complex
-
MacRae IJ, Ma E, Zhou M, et al. In vitro reconstitution of the human RISC-loading complex. Proc Natl Acad Sci USA 2008; 105: 512-7.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 512-517
-
-
MacRae, I.J.1
Ma, E.2
Zhou, M.3
-
18
-
-
0142165224
-
Functional siRNAs and miRNAs exhibit strand bias
-
Khvorova A, Reynolds A, Jayasena SD. Functional siRNAs and miRNAs exhibit strand bias. Cell 2003; 115: 209-16.
-
(2003)
Cell
, vol.115
, pp. 209-216
-
-
Khvorova, A.1
Reynolds, A.2
Jayasena, S.D.3
-
19
-
-
37549014207
-
Argonaute proteins: Key players in RNA silencing
-
Hutvagner G, Simard MJ. Argonaute proteins: key players in RNA silencing. Nat Rev Mol Cell Biol 2008; 9: 22-32.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 22-32
-
-
Hutvagner, G.1
Simard, M.J.2
-
20
-
-
33845755467
-
Illuminating the silence: Understanding the structure and function of small RNAs
-
Rana TM. Illuminating the silence: understanding the structure and function of small RNAs. Nat Rev Mol Cell Biol 2007; 8: 23-36.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 23-36
-
-
Rana, T.M.1
-
21
-
-
0346094457
-
Prediction of mammalian microRNA targets
-
Lewis BP, Shih IH, Jones-Rhoades MW, et al. Prediction of mammalian microRNA targets. Cell 2003; 115: 787-98.
-
(2003)
Cell
, vol.115
, pp. 787-798
-
-
Lewis, B.P.1
Shih, I.H.2
Jones-Rhoades, M.W.3
-
22
-
-
34250829042
-
Chemical synthesis of a very long oligoribonucleotide with 2-cyanoethoxymethyl (CEM) as the 2'-O-protecting group: Structural identification and biological activity of a synthetic 110mer precursor-microRNA candidate
-
Shiba Y, Masuda H, Watanabe N, et al. Chemical synthesis of a very long oligoribonucleotide with 2-cyanoethoxymethyl (CEM) as the 2'-O-protecting group: structural identification and biological activity of a synthetic 110mer precursor-microRNA candidate. Nucleic Acids Res 2007; 35: 3287-96.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 3287-3296
-
-
Shiba, Y.1
Masuda, H.2
Watanabe, N.3
-
23
-
-
33645500266
-
Progress towards in vivo use of siRNAs
-
Behlke MA. Progress towards in vivo use of siRNAs. Mol Ther 2006; 13: 644-70.
-
(2006)
Mol Ther
, vol.13
, pp. 644-670
-
-
Behlke, M.A.1
-
24
-
-
57349134691
-
Chemical modification of siRNAs for in vivo use
-
Behlke MA. Chemical modification of siRNAs for in vivo use. Oligonucleotides 2008; 18: 305-19.
-
(2008)
Oligonucleotides
, vol.18
, pp. 305-319
-
-
Behlke, M.A.1
-
25
-
-
23444445660
-
Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs
-
Morrissey DV, Lockridge JA, Shaw L, et al. Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs. Nat Biotechnol 2005; 23: 1002-7.
-
(2005)
Nat Biotechnol
, vol.23
, pp. 1002-1007
-
-
Morrissey, D.V.1
Lockridge, J.A.2
Shaw, L.3
-
26
-
-
34250674078
-
RNA interference tolerates 2′-fluoro modifications at the Argonaute2 cleavage site
-
Muhonen P, Tennila T, Azhayeva E, et al. RNA interference tolerates 2′-fluoro modifications at the Argonaute2 cleavage site. Chem Biodivers 2007; 4: 858-73.
-
(2007)
Chem Biodivers
, vol.4
, pp. 858-873
-
-
Muhonen, P.1
Tennila, T.2
Azhayeva, E.3
-
27
-
-
34548108038
-
2′-O-methyl-modified RNAs act as TLR7 antagonists
-
Robbins M, Judge A, Liang L, et al. 2′-O-methyl-modified RNAs act as TLR7 antagonists. Mol Ther 2007; 15: 1663-9.
-
(2007)
Mol Ther
, vol.15
, pp. 1663-1669
-
-
Robbins, M.1
Judge, A.2
Liang, L.3
-
28
-
-
38649099969
-
Strand-specific 5′-O-methylation of siRNA duplexes controls guide strand selection and targeting specificity
-
Chen PY, Weinmann L, Gaidatzis D, et al. Strand-specific 5′-O-methylation of siRNA duplexes controls guide strand selection and targeting specificity. RNA 2008; 14: 263-74.
-
(2008)
RNA
, vol.14
, pp. 263-274
-
-
Chen, P.Y.1
Weinmann, L.2
Gaidatzis, D.3
-
29
-
-
34147180058
-
Evaluation of locked nucleic acid-modified small interfering RNA in vitro and in vivo
-
Mook OR, Baas F, de Wissel MB, et al. Evaluation of locked nucleic acid-modified small interfering RNA in vitro and in vivo. Mol Cancer Ther 2007; 6: 833-43.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 833-843
-
-
Mook, O.R.1
Baas, F.2
de Wissel, M.B.3
-
30
-
-
33745614074
-
Position-specific chemical modification of siRNAs reduces "off-target" transcript silencing
-
Jackson AL, Burchard J, Leake D, et al. Position-specific chemical modification of siRNAs reduces "off-target" transcript silencing. RNA 2006; 12: 1197-205.
-
(2006)
RNA
, vol.12
, pp. 1197-1205
-
-
Jackson, A.L.1
Burchard, J.2
Leake, D.3
-
31
-
-
33846902312
-
Antisense oligonucleotides containing locked nucleic acid improve potency but cause significant hepatotoxicity in animals
-
Swayze EE, Siwkowski AM, Wancewicz EV, et al. Antisense oligonucleotides containing locked nucleic acid improve potency but cause significant hepatotoxicity in animals. Nucleic Acids Res 2007; 35: 687-700.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 687-700
-
-
Swayze, E.E.1
Siwkowski, A.M.2
Wancewicz, E.V.3
-
32
-
-
9144247189
-
Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs
-
Soutschek J, Akinc A, Bramlage B, et al. Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs. Nature 2004; 432: 173-8.
-
(2004)
Nature
, vol.432
, pp. 173-178
-
-
Soutschek, J.1
Akinc, A.2
Bramlage, B.3
-
33
-
-
4444220551
-
Steroid and lipid conjugates of siRNAs to enhance cellular uptake and gene silencing in liver cells
-
Lorenz C, Hadwiger P, John M, et al. Steroid and lipid conjugates of siRNAs to enhance cellular uptake and gene silencing in liver cells. Bioorg Med Chem Lett 2004; 14: 4975-7.
-
(2004)
Bioorg Med Chem Lett
, vol.14
, pp. 4975-4977
-
-
Lorenz, C.1
Hadwiger, P.2
John, M.3
-
34
-
-
41149179660
-
Efficient in vivo delivery of siRNA to the liver by conjugation of alpha-tocopherol
-
Nishina K, Unno T, Uno Y, et al. Efficient in vivo delivery of siRNA to the liver by conjugation of alpha-tocopherol. Mol Ther 2008; 16: 734-40.
-
(2008)
Mol Ther
, vol.16
, pp. 734-740
-
-
Nishina, K.1
Unno, T.2
Uno, Y.3
-
35
-
-
33847195409
-
Specific inhibition of HBV replication in vitro and in vivo with expressed long hairpin RNA
-
Weinberg MS, Ely A, Barichievy S, et al. Specific inhibition of HBV replication in vitro and in vivo with expressed long hairpin RNA. Mol Ther 2007; 15: 534-41.
-
(2007)
Mol Ther
, vol.15
, pp. 534-541
-
-
Weinberg, M.S.1
Ely, A.2
Barichievy, S.3
-
36
-
-
29244433509
-
Escape from the interferon response associated with RNA interference using vectors that encode long modified hairpin-RNA
-
Akashi H, Miyagishi M, Yokota T, et al. Escape from the interferon response associated with RNA interference using vectors that encode long modified hairpin-RNA. Mol BioSyst 2005; 1: 382-90.
-
(2005)
Mol BioSyst
, vol.1
, pp. 382-390
-
-
Akashi, H.1
Miyagishi, M.2
Yokota, T.3
-
37
-
-
33646767492
-
Intracellular-diced dsRNA has enhanced efficacy for silencing HCV RNA and overcomes variation in the viral genotype
-
Watanabe T, Sudoh M, Miyagishi M, et al. Intracellular-diced dsRNA has enhanced efficacy for silencing HCV RNA and overcomes variation in the viral genotype. Gene Ther 2006; 13: 883-92.
-
(2006)
Gene Ther
, vol.13
, pp. 883-892
-
-
Watanabe, T.1
Sudoh, M.2
Miyagishi, M.3
-
38
-
-
33745299723
-
Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways
-
Grimm D, Streetz KL, Jopling CL, et al. Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways. Nature 2006; 441: 537-41.
-
(2006)
Nature
, vol.441
, pp. 537-541
-
-
Grimm, D.1
Streetz, K.L.2
Jopling, C.L.3
-
39
-
-
2942707780
-
RNAi expression vectors in mammalian cells
-
Miyagishi M, Taira K. RNAi expression vectors in mammalian cells. Methods Mol Biol 2004; 252: 483-91.
-
(2004)
Methods Mol Biol
, vol.252
, pp. 483-491
-
-
Miyagishi, M.1
Taira, K.2
-
40
-
-
44349178186
-
Expressed anti-HBV primary microRNA shuttles inhibit viral replication efficiently in vitro and in vivo
-
Ely A, Naidoo T, Mufamadi S, et al. Expressed anti-HBV primary microRNA shuttles inhibit viral replication efficiently in vitro and in vivo. Mol Ther 2008; 16: 1105-12.
-
(2008)
Mol Ther
, vol.16
, pp. 1105-1112
-
-
Ely, A.1
Naidoo, T.2
Mufamadi, S.3
-
41
-
-
44349164025
-
Inhibition of HIV-1 by multiple siRNAs expressed from a single microRNA polycistron
-
Liu YP, Haasnoot J, ter Brake O, et al. Inhibition of HIV-1 by multiple siRNAs expressed from a single microRNA polycistron. Nucleic Acids Res 2008; 36: 2811-24.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 2811-2824
-
-
Liu, Y.P.1
Haasnoot, J.2
ter Brake, O.3
-
42
-
-
34748823119
-
Defining the optimal parameters for hairpin-based knockdown constructs
-
Li L, Lin X, Khvorova A, et al. Defining the optimal parameters for hairpin-based knockdown constructs. RNA 2007; 13: 1765-74.
-
(2007)
RNA
, vol.13
, pp. 1765-1774
-
-
Li, L.1
Lin, X.2
Khvorova, A.3
-
43
-
-
33646196844
-
Current strategies and future directions for eluding adenoviral vector immunity
-
Bangari DS, Mittal SK. Current strategies and future directions for eluding adenoviral vector immunity. Curr Gene Ther 2006; 6: 215-26.
-
(2006)
Curr Gene Ther
, vol.6
, pp. 215-226
-
-
Bangari, D.S.1
Mittal, S.K.2
-
44
-
-
0034830243
-
CAR-binding ablation does not change biodistribution and toxicity of adenoviral vectors
-
Alemany R, Curiel DT. CAR-binding ablation does not change biodistribution and toxicity of adenoviral vectors. Gene Ther 2001; 8: 1347-53.
-
(2001)
Gene Ther
, vol.8
, pp. 1347-1353
-
-
Alemany, R.1
Curiel, D.T.2
-
45
-
-
10744221060
-
Receptor interactions involved in adenoviral-mediated gene delivery after systemic administration in non-human primates
-
Smith TA, Idamakanti N, Marshall-Neff J, et al. Receptor interactions involved in adenoviral-mediated gene delivery after systemic administration in non-human primates. Hum Gene Ther 2003; 14: 1595-604.
-
(2003)
Hum Gene Ther
, vol.14
, pp. 1595-1604
-
-
Smith, T.A.1
Idamakanti, N.2
Marshall-Neff, J.3
-
46
-
-
38849134279
-
Adenovirus serotype 5 hexon mediates liver gene transfer
-
Waddington SN, McVey JH, Bhella D, et al. Adenovirus serotype 5 hexon mediates liver gene transfer. Cell 2008; 132: 397-409.
-
(2008)
Cell
, vol.132
, pp. 397-409
-
-
Waddington, S.N.1
McVey, J.H.2
Bhella, D.3
-
47
-
-
31144477390
-
Adenovirus vectors deleted for genes essential for viral DNA replication
-
Schaack J. Adenovirus vectors deleted for genes essential for viral DNA replication. Front Biosci 2005; 10: 1146-55.
-
(2005)
Front Biosci
, vol.10
, pp. 1146-1155
-
-
Schaack, J.1
-
48
-
-
0142089747
-
Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer
-
Raper SE, Chirmule N, Lee FS, et al. Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer. Mol Genet Metab 2003; 80: 148-58.
-
(2003)
Mol Genet Metab
, vol.80
, pp. 148-158
-
-
Raper, S.E.1
Chirmule, N.2
Lee, F.S.3
-
49
-
-
0034986416
-
Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophages
-
Zhang Y, Chirmule N, Gao GP, et al. Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophages. Mol Ther 2001; 3: 697-707.
-
(2001)
Mol Ther
, vol.3
, pp. 697-707
-
-
Zhang, Y.1
Chirmule, N.2
Gao, G.P.3
-
50
-
-
0035062597
-
Noncytolytic control of viral infections by the innate and adaptive immune response
-
Guidotti LG, Chisari FV. Noncytolytic control of viral infections by the innate and adaptive immune response. Annu Rev Immunol 2001; 19: 65-91.
-
(2001)
Annu Rev Immunol
, vol.19
, pp. 65-91
-
-
Guidotti, L.G.1
Chisari, F.V.2
-
51
-
-
37549008707
-
Modification of adenovirus gene transfer vectors with synthetic polymers: A scientific review and technical guide
-
Kreppel F, Kochanek S. Modification of adenovirus gene transfer vectors with synthetic polymers: a scientific review and technical guide. Mol Ther 2008; 16: 16-29.
-
(2008)
Mol Ther
, vol.16
, pp. 16-29
-
-
Kreppel, F.1
Kochanek, S.2
-
52
-
-
57049105313
-
Efficient inhibition of hepatitis B virus replication in vivo using peg-modified adenovirus vectors
-
Epub ahead of print
-
Crowther C, Ely A, Hornby J, et al. Efficient inhibition of hepatitis B virus replication in vivo using peg-modified adenovirus vectors. Hum Gene Ther 2008. [Epub ahead of print]
-
(2008)
Hum Gene Ther
-
-
Crowther, C.1
Ely, A.2
Hornby, J.3
-
53
-
-
17844393413
-
Activation of innate immunity in nonhuman primates following intraportal administration of adenoviral vectors
-
Schnell MA, Zhang Y, Tazelaar J, et al. Activation of innate immunity in nonhuman primates following intraportal administration of adenoviral vectors. Mol Ther 2001; 3: 708-22.
-
(2001)
Mol Ther
, vol.3
, pp. 708-722
-
-
Schnell, M.A.1
Zhang, Y.2
Tazelaar, J.3
-
54
-
-
54249126862
-
Gene therapy using adeno-associated virus vectors
-
Daya S, Berns KI. Gene therapy using adeno-associated virus vectors. Clin Microbiol Rev 2008; 21: 583-93.
-
(2008)
Clin Microbiol Rev
, vol.21
, pp. 583-593
-
-
Daya, S.1
Berns, K.I.2
-
55
-
-
45749138773
-
Recombinant adeno-associated virus transduction and integration
-
Schultz BR, Chamberlain JS. Recombinant adeno-associated virus transduction and integration. Mol Ther 2008; 16: 1189-99.
-
(2008)
Mol Ther
, vol.16
, pp. 1189-1199
-
-
Schultz, B.R.1
Chamberlain, J.S.2
-
56
-
-
48949120141
-
Recent developments in adeno-associated virus vector technology
-
Buning H, Perabo L, Coutelle O, et al. Recent developments in adeno-associated virus vector technology. J Gene Med 2008; 10: 717-33.
-
(2008)
J Gene Med
, vol.10
, pp. 717-733
-
-
Buning, H.1
Perabo, L.2
Coutelle, O.3
-
57
-
-
0031906147
-
Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions
-
Summerford C, Samulski RJ. Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions. J Virol 2004; 72: 1438-45.
-
(2004)
J Virol
, vol.72
, pp. 1438-1445
-
-
Summerford, C.1
Samulski, R.J.2
-
58
-
-
4644346385
-
Improving rAAV production and purification: Towards the definition of a scaleable process
-
Blouin V, Brument N, Toublanc E, et al. Improving rAAV production and purification: towards the definition of a scaleable process. J Gene Med 2004; 6(Suppl 1): S223-8.
-
(2004)
J Gene Med
, vol.6
, Issue.SUPPL. 1
-
-
Blouin, V.1
Brument, N.2
Toublanc, E.3
-
59
-
-
0036431701
-
Insect cells as a factory to produce adeno-associated virus type 2 vectors
-
Urabe M, Ding C, Kotin RM. Insect cells as a factory to produce adeno-associated virus type 2 vectors. Hum Gene Ther 2002; 13: 1935-43.
-
(2002)
Hum Gene Ther
, vol.13
, pp. 1935-1943
-
-
Urabe, M.1
Ding, C.2
Kotin, R.M.3
-
60
-
-
42549161844
-
The host response to adenovirus, helper-dependent adenovirus, and adeno-associated virus in mouse liver
-
McCaffrey AP, Fawcett P, Nakai H, et al. The host response to adenovirus, helper-dependent adenovirus, and adeno-associated virus in mouse liver. Mol Ther 2008; 16: 931-41.
-
(2008)
Mol Ther
, vol.16
, pp. 931-941
-
-
McCaffrey, A.P.1
Fawcett, P.2
Nakai, H.3
-
61
-
-
60649100077
-
Applications of lentiviral vectors for shRNA delivery and transgenesis
-
Singer O, Verma IM. Applications of lentiviral vectors for shRNA delivery and transgenesis. Curr Gene Ther 2008; 8: 483-8.
-
(2008)
Curr Gene Ther
, vol.8
, pp. 483-488
-
-
Singer, O.1
Verma, I.M.2
-
63
-
-
60649104262
-
Mechanisms governing lentivirus integration site selection
-
Ciuffi A. Mechanisms governing lentivirus integration site selection. Curr Gene Ther 2008; 8: 419-29.
-
(2008)
Curr Gene Ther
, vol.8
, pp. 419-429
-
-
Ciuffi, A.1
-
64
-
-
60649084807
-
Strategies for targeting lentiviral vectors
-
Frecha C, Szecsi J, Cosset FL, et al. Strategies for targeting lentiviral vectors. Curr Gene Ther 2008; 8: 449-60.
-
(2008)
Curr Gene Ther
, vol.8
, pp. 449-460
-
-
Frecha, C.1
Szecsi, J.2
Cosset, F.L.3
-
65
-
-
60649116702
-
Applications of lentiviral vectors for biology and gene therapy of neurological disorders
-
Lundberg C, Bjorklund T, Carlsson T, et al. Applications of lentiviral vectors for biology and gene therapy of neurological disorders. Curr Gene Ther 2008; 8: 461-73.
-
(2008)
Curr Gene Ther
, vol.8
, pp. 461-473
-
-
Lundberg, C.1
Bjorklund, T.2
Carlsson, T.3
-
67
-
-
60649103432
-
Clinical application of lentiviral vectors - concepts and practice
-
Schambach A, Baum C. Clinical application of lentiviral vectors - concepts and practice. Curr Gene Ther 2008; 8: 474-82.
-
(2008)
Curr Gene Ther
, vol.8
, pp. 474-482
-
-
Schambach, A.1
Baum, C.2
-
68
-
-
60649100499
-
Development and applications of non-HIV-based lentiviral vectors in neurological disorders
-
Valori CF, Ning K, Wyles M, et al. Development and applications of non-HIV-based lentiviral vectors in neurological disorders. Curr Gene Ther 2008; 8: 406-18.
-
(2008)
Curr Gene Ther
, vol.8
, pp. 406-418
-
-
Valori, C.F.1
Ning, K.2
Wyles, M.3
-
69
-
-
0033986340
-
Efficient lentiviral transduction of liver requires cell cycling in vivo
-
Park F, Ohashi K, Chiu W, et al. Efficient lentiviral transduction of liver requires cell cycling in vivo. Nat Genet 2000; 24: 49-52.
-
(2000)
Nat Genet
, vol.24
, pp. 49-52
-
-
Park, F.1
Ohashi, K.2
Chiu, W.3
-
70
-
-
34547487035
-
Lentivirus-mediated RNA interference targeting enhancer of zeste homolog 2 inhibits hepatocellular carcinoma growth through down-regulation of stathmin
-
Chen Y, Lin MC, Yao H, et al. Lentivirus-mediated RNA interference targeting enhancer of zeste homolog 2 inhibits hepatocellular carcinoma growth through down-regulation of stathmin. Hepatology 2007; 46: 200-8.
-
(2007)
Hepatology
, vol.46
, pp. 200-208
-
-
Chen, Y.1
Lin, M.C.2
Yao, H.3
-
71
-
-
33847279353
-
Overlapping enhancer/promoter and transcriptional termination signals in the lentiviral long terminal repeat
-
Yang Q, Lucas A, Son S, et al. Overlapping enhancer/promoter and transcriptional termination signals in the lentiviral long terminal repeat. Retrovirology 2007; 4: 4.
-
(2007)
Retrovirology
, vol.4
, pp. 4
-
-
Yang, Q.1
Lucas, A.2
Son, S.3
-
72
-
-
0036632178
-
RNA 3′ readthrough of oncoretrovirus and lentivirus: Implications for vector safety and efficacy
-
Zaiss AK, Son S, Chang LJ. RNA 3′ readthrough of oncoretrovirus and lentivirus: implications for vector safety and efficacy. J Virol 2002; 76: 7209-19.
-
(2002)
J Virol
, vol.76
, pp. 7209-7219
-
-
Zaiss, A.K.1
Son, S.2
Chang, L.J.3
-
73
-
-
39849094315
-
Globin lentiviral vector insertions can perturb the expression of endogenous genes in beta-thalassemic hematopoietic cells
-
Hargrove PW, Kepes S, Hanawa H, et al. Globin lentiviral vector insertions can perturb the expression of endogenous genes in beta-thalassemic hematopoietic cells. Mol Ther 2008; 16: 525-33.
-
(2008)
Mol Ther
, vol.16
, pp. 525-533
-
-
Hargrove, P.W.1
Kepes, S.2
Hanawa, H.3
-
74
-
-
0030966386
-
Inhibition of recombinant human immunodeficiency virus type 1 replication by a site-specific recombinase
-
Flowers CC, Woffendin C, Petryniak J, et al. Inhibition of recombinant human immunodeficiency virus type 1 replication by a site-specific recombinase. J Virol 1997; 71: 2685-92.
-
(1997)
J Virol
, vol.71
, pp. 2685-2692
-
-
Flowers, C.C.1
Woffendin, C.2
Petryniak, J.3
-
75
-
-
34250664283
-
Design and cloning of lentiviral vectors expressing small interfering RNAs
-
Tiscornia G, Singer O, Verma IM. Design and cloning of lentiviral vectors expressing small interfering RNAs. Nat Protoc 2006; 1: 234-40.
-
(2006)
Nat Protoc
, vol.1
, pp. 234-240
-
-
Tiscornia, G.1
Singer, O.2
Verma, I.M.3
-
76
-
-
3142708570
-
Cre-lox-regulated conditional RNA interference from transgenes
-
Ventura A, Meissner A, Dillon CP, et al. Cre-lox-regulated conditional RNA interference from transgenes. Proc Natl Acad Sci USA 2004; 101: 10380-5.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 10380-10385
-
-
Ventura, A.1
Meissner, A.2
Dillon, C.P.3
-
77
-
-
2442584612
-
CRE recombinase-inducible RNA interference mediated by lentiviral vectors
-
Tiscornia G, Tergaonkar V, Galimi F, et al. CRE recombinase-inducible RNA interference mediated by lentiviral vectors. Proc Natl Acad Sci USA 2004; 101: 7347-51.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 7347-7351
-
-
Tiscornia, G.1
Tergaonkar, V.2
Galimi, F.3
-
78
-
-
59249088227
-
Physicochemical parameters of non-viral vectors that govern transfection efficiency
-
Barteau B, Chevre R, Letrou-Bonneval E, et al. Physicochemical parameters of non-viral vectors that govern transfection efficiency. Curr Gene Ther 2008; 8: 313-23.
-
(2008)
Curr Gene Ther
, vol.8
, pp. 313-323
-
-
Barteau, B.1
Chevre, R.2
Letrou-Bonneval, E.3
-
79
-
-
59249092022
-
Muscular gene transfer using nonviral vectors
-
Braun S. Muscular gene transfer using nonviral vectors. Curr Gene Ther 2008; 8: 391-405.
-
(2008)
Curr Gene Ther
, vol.8
, pp. 391-405
-
-
Braun, S.1
-
80
-
-
59249084751
-
Sustained transgene expression using MAR elements
-
Harraghy N, Gaussin A, Mermod N. Sustained transgene expression using MAR elements. Curr Gene Ther 2008; 8: 353-66.
-
(2008)
Curr Gene Ther
, vol.8
, pp. 353-366
-
-
Harraghy, N.1
Gaussin, A.2
Mermod, N.3
-
81
-
-
59249105606
-
Polymer-based gene delivery: A current review on the uptake and intracellular trafficking of polyplexes
-
Midoux P, Breuzard G, Gomez JP, et al. Polymer-based gene delivery: a current review on the uptake and intracellular trafficking of polyplexes. Curr Gene Ther 2008; 8: 335-52.
-
(2008)
Curr Gene Ther
, vol.8
, pp. 335-352
-
-
Midoux, P.1
Breuzard, G.2
Gomez, J.P.3
-
82
-
-
59249085987
-
Progress in cationic lipid-mediated gene transfection: A series of bio-inspired lipids as an example
-
Montier T, Benvegnu T, Jaffres PA, et al. Progress in cationic lipid-mediated gene transfection: a series of bio-inspired lipids as an example. Curr Gene Ther 2008; 8: 296-312.
-
(2008)
Curr Gene Ther
, vol.8
, pp. 296-312
-
-
Montier, T.1
Benvegnu, T.2
Jaffres, P.A.3
-
83
-
-
59249093855
-
Sustained transgene expression using non-viral enzymatic systems for stable chromosomal integration
-
Palazzoli F, Carnus E, Wells DJ, et al. Sustained transgene expression using non-viral enzymatic systems for stable chromosomal integration. Curr Gene Ther 2008; 8: 367-90.
-
(2008)
Curr Gene Ther
, vol.8
, pp. 367-390
-
-
Palazzoli, F.1
Carnus, E.2
Wells, D.J.3
-
84
-
-
59249099019
-
Extracellular targeting of synthetic therapeutic nucleic acid formulations
-
Philipp A, Meyer M, Wagner E. Extracellular targeting of synthetic therapeutic nucleic acid formulations. Curr Gene Ther 2008; 8: 324-34.
-
(2008)
Curr Gene Ther
, vol.8
, pp. 324-334
-
-
Philipp, A.1
Meyer, M.2
Wagner, E.3
-
85
-
-
59249094709
-
Convergence of opposite sciences for the future development of non viral gene therapy
-
Pitard B. Convergence of opposite sciences for the future development of non viral gene therapy. Curr Gene Ther 2008; 8: 295.
-
(2008)
Curr Gene Ther
, vol.8
, pp. 295
-
-
Pitard, B.1
-
86
-
-
0023811723
-
Receptor-mediated gene delivery and expression in vivo
-
Wu GY, Wu CH. Receptor-mediated gene delivery and expression in vivo. J Biol Chem 1988; 263: 14621-4.
-
(1988)
J Biol Chem
, vol.263
, pp. 14621-14624
-
-
Wu, G.Y.1
Wu, C.H.2
-
87
-
-
12244291636
-
New multivalent cationic lipids reveal bell curve for transfection efficiency versus membrane charge density: Lipid-DNA complexes for gene delivery
-
Ahmad A, Evans HM, Ewert K, et al. New multivalent cationic lipids reveal bell curve for transfection efficiency versus membrane charge density: lipid-DNA complexes for gene delivery. J Gene Med 2005; 7: 739-48.
-
(2005)
J Gene Med
, vol.7
, pp. 739-748
-
-
Ahmad, A.1
Evans, H.M.2
Ewert, K.3
-
88
-
-
47749109054
-
Transitions between distinct compaction regimes in complexes of multivalent cationic lipids and DNA
-
Farago O, Ewert K, Ahmad A, et al. Transitions between distinct compaction regimes in complexes of multivalent cationic lipids and DNA. Biophys J 2008; 95: 836846.
-
(2008)
Biophys J
, vol.95
, pp. 836846
-
-
Farago, O.1
Ewert, K.2
Ahmad, A.3
-
89
-
-
43049176170
-
A combinatorial library of lipid-like materials for delivery of RNAi therapeutics
-
Akinc A, Zumbuehl A, Goldberg M, et al. A combinatorial library of lipid-like materials for delivery of RNAi therapeutics. Nat Biotechnol 2008; 26: 561-9.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 561-569
-
-
Akinc, A.1
Zumbuehl, A.2
Goldberg, M.3
-
90
-
-
50149101511
-
Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates
-
Frank-Kamenetsky M, Grefhorst A, Anderson NN, et al. Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates. Proc Natl Acad Sci USA 2008; 105: 11915-20.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 11915-11920
-
-
Frank-Kamenetsky, M.1
Grefhorst, A.2
Anderson, N.N.3
-
91
-
-
6344291687
-
Lipidic carriers of siRNA: Differences in the formulation, cellular uptake, and delivery with plasmid DNA
-
Spagnou S, Miller AD, Keller M. Lipidic carriers of siRNA: differences in the formulation, cellular uptake, and delivery with plasmid DNA. Biochemistry 2004; 43: 13348-56.
-
(2004)
Biochemistry
, vol.43
, pp. 13348-13356
-
-
Spagnou, S.1
Miller, A.D.2
Keller, M.3
-
92
-
-
34249279852
-
Systemic and specific delivery of small interfering RNAs to the liver mediated by apolipoprotein A-I
-
Kim SI, Shin D, Choi TH, et al. Systemic and specific delivery of small interfering RNAs to the liver mediated by apolipoprotein A-I. Mol Ther 2008; 15: 1145-52.
-
(2008)
Mol Ther
, vol.15
, pp. 1145-1152
-
-
Kim, S.I.1
Shin, D.2
Choi, T.H.3
-
93
-
-
41849117310
-
Resolution of liver cirrhosis using vitamin A-coupled liposomes to deliver siRNA against a collagen-specific chaperone
-
Sato Y, Murase K, Kato J, et al. Resolution of liver cirrhosis using vitamin A-coupled liposomes to deliver siRNA against a collagen-specific chaperone. Nat Biotechnol 2008; 26: 431-42.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 431-442
-
-
Sato, Y.1
Murase, K.2
Kato, J.3
-
94
-
-
33646185371
-
RNAi-mediated gene silencing in non-human primates
-
Zimmermann TS, Lee AC, Akinc A, et al. RNAi-mediated gene silencing in non-human primates. Nature 2006; 441: 111-4.
-
(2006)
Nature
, vol.441
, pp. 111-114
-
-
Zimmermann, T.S.1
Lee, A.C.2
Akinc, A.3
-
95
-
-
0034928111
-
Hepatitis B virus and hepatocellular carcinoma
-
Arbuthnot P, Kew M. Hepatitis B virus and hepatocellular carcinoma. Int J Exp Pathol 2001; 82: 77-100.
-
(2001)
Int J Exp Pathol
, vol.82
, pp. 77-100
-
-
Arbuthnot, P.1
Kew, M.2
-
96
-
-
38549137325
-
Antiviral treatment of chronic hepatitis B virus infections: The past, the present and the future
-
Ferir G, Kaptein S, Neyts J, et al. Antiviral treatment of chronic hepatitis B virus infections: the past, the present and the future. Rev Med Virol 2008; 18: 19-34.
-
(2008)
Rev Med Virol
, vol.18
, pp. 19-34
-
-
Ferir, G.1
Kaptein, S.2
Neyts, J.3
-
97
-
-
40149095458
-
Chronic hepatitis B: Preventing, detecting, and managing viral resistance
-
Keeffe EB, Dieterich DT, Pawlotsky JM, et al. Chronic hepatitis B: preventing, detecting, and managing viral resistance. Clin Gastroenterol Hepatol 2008; 6: 268-74.
-
(2008)
Clin Gastroenterol Hepatol
, vol.6
, pp. 268-274
-
-
Keeffe, E.B.1
Dieterich, D.T.2
Pawlotsky, J.M.3
-
99
-
-
0038023197
-
Inhibition of hepatitis B virus in mice by RNA interference
-
McCaffrey AP, Nakai H, Pandey K, et al. Inhibition of hepatitis B virus in mice by RNA interference. Nat Biotechnol 2003; 21: 639-44.
-
(2003)
Nat Biotechnol
, vol.21
, pp. 639-644
-
-
McCaffrey, A.P.1
Nakai, H.2
Pandey, K.3
-
100
-
-
41849137252
-
Harnessing the RNA interference pathway to advance treatment and prevention of hepatocellular carcinoma
-
Arbuthnot P, Thompson LJ. Harnessing the RNA interference pathway to advance treatment and prevention of hepatocellular carcinoma. World J Gastroenterol 2008; 14: 1670-81.
-
(2008)
World J Gastroenterol
, vol.14
, pp. 1670-1681
-
-
Arbuthnot, P.1
Thompson, L.J.2
-
101
-
-
0037108818
-
Hydrodynamic injection of viral DNA: A mouse model of acute hepatitis B virus infection
-
Yang PL, Althage A, Chung J, et al. Hydrodynamic injection of viral DNA: a mouse model of acute hepatitis B virus infection. Proc Natl Acad Sci USA 2002; 99: 13825-30.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 13825-13830
-
-
Yang, P.L.1
Althage, A.2
Chung, J.3
-
102
-
-
30344453089
-
Effective inhibition of HBV replication in vivo by anti-HBx short hairpin RNAs
-
Carmona S, Ely A, Crowther C, et al. Effective inhibition of HBV replication in vivo by anti-HBx short hairpin RNAs. Mol Ther 2006; 13: 411-21.
-
(2006)
Mol Ther
, vol.13
, pp. 411-421
-
-
Carmona, S.1
Ely, A.2
Crowther, C.3
-
103
-
-
14144255291
-
Clearance of hepatitis B virus from the liver of transgenic mice by short hairpin RNAs
-
Uprichard SL, Boyd B, Althage A, et al. Clearance of hepatitis B virus from the liver of transgenic mice by short hairpin RNAs. Proc Natl Acad Sci USA 2005; 102: 773-8.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 773-778
-
-
Uprichard, S.L.1
Boyd, B.2
Althage, A.3
-
104
-
-
49349104504
-
Exploring gene-deleted adenoviral vectors for delivery of short hairpin RNAs and reduction of hepatitis B virus infection in mice
-
Rauschhuber C, Xu H, Salazar FH, et al. Exploring gene-deleted adenoviral vectors for delivery of short hairpin RNAs and reduction of hepatitis B virus infection in mice. J Gene Med 2008; 10: 878-89.
-
(2008)
J Gene Med
, vol.10
, pp. 878-889
-
-
Rauschhuber, C.1
Xu, H.2
Salazar, F.H.3
-
105
-
-
33845656937
-
Long-term inhibition of hepatitis B virus in transgenic mice by double-stranded adeno-associated virus 8-delivered short hairpin RNA
-
Chen CC, Ko TM, Ma HI, et al. Long-term inhibition of hepatitis B virus in transgenic mice by double-stranded adeno-associated virus 8-delivered short hairpin RNA. Gene Ther 2007; 14: 11-9.
-
(2007)
Gene Ther
, vol.14
, pp. 11-19
-
-
Chen, C.C.1
Ko, T.M.2
Ma, H.I.3
-
106
-
-
63649148742
-
Comparative study of antihepatitis B virus RNA interference by double-stranded adeno-associated virus serotypes 7, 8, and 9
-
Chen CC, Sun CP, Ma HI, et al. Comparative study of antihepatitis B virus RNA interference by double-stranded adeno-associated virus serotypes 7, 8, and 9. Mol Ther 2009; 17: 352-59.
-
(2009)
Mol Ther
, vol.17
, pp. 352-359
-
-
Chen, C.C.1
Sun, C.P.2
Ma, H.I.3
-
107
-
-
65949104923
-
Controlling HBV replication in vivo by intravenous administration of triggered PEGylated siRNA-nanoparticles
-
in press
-
Carmona S, Keller M, Jorgensen MR, et al. Controlling HBV replication in vivo by intravenous administration of triggered PEGylated siRNA-nanoparticles. Mol Pharm 2008. in press.
-
(2008)
Mol Pharm
-
-
Carmona, S.1
Keller, M.2
Jorgensen, M.R.3
-
108
-
-
0033916804
-
Epidemiology of hepatitis C: Geographic differences and temporal trends
-
Wasley A, Alter MJ. Epidemiology of hepatitis C: geographic differences and temporal trends. Semin Liver Dis 2000; 20: 1-16.
-
(2000)
Semin Liver Dis
, vol.20
, pp. 1-16
-
-
Wasley, A.1
Alter, M.J.2
-
109
-
-
11144246127
-
Novel insights into hepatitis C virus replication and persistence
-
Bartenschlager R, Frese M, Pietschmann T. Novel insights into hepatitis C virus replication and persistence. Adv Virus Res 2004; 63: 71-180.
-
(2004)
Adv Virus Res
, vol.63
, pp. 71-180
-
-
Bartenschlager, R.1
Frese, M.2
Pietschmann, T.3
-
110
-
-
12144289381
-
Alternative approaches for efficient inhibition of hepatitis C virus RNA replication by small interfering RNAs
-
Kronke J, Kittler R, Buchholz F, et al. Alternative approaches for efficient inhibition of hepatitis C virus RNA replication by small interfering RNAs. J Virol 2004; 78: 3436-46.
-
(2004)
J Virol
, vol.78
, pp. 3436-3446
-
-
Kronke, J.1
Kittler, R.2
Buchholz, F.3
-
111
-
-
1842584178
-
Interfering with hepatitis C virus RNA replication
-
Randall G, Rice CM. Interfering with hepatitis C virus RNA replication. Virus Res 2004; 102: 19-25.
-
(2004)
Virus Res
, vol.102
, pp. 19-25
-
-
Randall, G.1
Rice, C.M.2
-
112
-
-
4143088066
-
Suppression of hepatitis C virus replicon by RNA interference directed against the NS3 and NS5B regions of the viral genome
-
Takigawa Y, Nagano-Fujii M, Deng L, et al. Suppression of hepatitis C virus replicon by RNA interference directed against the NS3 and NS5B regions of the viral genome. Microbiol Immunol 2004; 48: 591-8.
-
(2004)
Microbiol Immunol
, vol.48
, pp. 591-598
-
-
Takigawa, Y.1
Nagano-Fujii, M.2
Deng, L.3
-
113
-
-
23844432445
-
Small hairpin RNAs efficiently inhibit hepatitis C IRES-mediated gene expression in human tissue culture cells and a mouse model
-
Wang Q, Contag CH, Ilves H, et al. Small hairpin RNAs efficiently inhibit hepatitis C IRES-mediated gene expression in human tissue culture cells and a mouse model. Mol Ther 2005; 12: 562-8.
-
(2005)
Mol Ther
, vol.12
, pp. 562-568
-
-
Wang, Q.1
Contag, C.H.2
Ilves, H.3
-
114
-
-
10744230911
-
-
Yokota T, Sakamoto N, Enomoto N, et al. Inhibition of intracellular hepatitis C virus replication by synthetic and vector-derived small interfering RNAs. EMBO 2003; Rep 4: 602-8.
-
Yokota T, Sakamoto N, Enomoto N, et al. Inhibition of intracellular hepatitis C virus replication by synthetic and vector-derived small interfering RNAs. EMBO 2003; Rep 4: 602-8.
-
-
-
-
115
-
-
1542330798
-
Down-regulation of viral replication by adenoviral-mediated expression of siRNA against cellular cofactors for hepatitis C virus
-
Zhang J, Yamada O, Sakamoto T, et al. Down-regulation of viral replication by adenoviral-mediated expression of siRNA against cellular cofactors for hepatitis C virus. Virology 320: 135-43.
-
Virology
, vol.320
, pp. 135-143
-
-
Zhang, J.1
Yamada, O.2
Sakamoto, T.3
-
116
-
-
16844371596
-
Role of La autoantigen and polypyrimidine tract-binding protein in HCV replication
-
Domitrovich AM, Diebel KW, Ali N, et al. Role of La autoantigen and polypyrimidine tract-binding protein in HCV replication. Virology 2005; 335: 72-86.
-
(2005)
Virology
, vol.335
, pp. 72-86
-
-
Domitrovich, A.M.1
Diebel, K.W.2
Ali, N.3
-
117
-
-
24144468662
-
Suppression of hepatitis C virus replication by cyclosporin a is mediated by blockade of cyclophilins
-
Nakagawa M, Sakamoto N, Tanabe Y, et al. Suppression of hepatitis C virus replication by cyclosporin a is mediated by blockade of cyclophilins. Gastroenterology 2005; 129: 1031-41.
-
(2005)
Gastroenterology
, vol.129
, pp. 1031-1041
-
-
Nakagawa, M.1
Sakamoto, N.2
Tanabe, Y.3
-
118
-
-
24644483623
-
Modulation of hepatitis C virus RNA abundance by a liver-specific microRNA
-
Jopling CL, Yi M, Lancaster AM, et al. Modulation of hepatitis C virus RNA abundance by a liver-specific microRNA. Science 2005; 309: 1577-81.
-
(2005)
Science
, vol.309
, pp. 1577-1581
-
-
Jopling, C.L.1
Yi, M.2
Lancaster, A.M.3
-
119
-
-
34848878881
-
Reciprocal effects of micro-RNA-122 on expression of heme oxygenase-1 and hepatitis C virus genes in human hepatocytes
-
Shan Y, Zheng J, Lambrecht RW, et al. Reciprocal effects of micro-RNA-122 on expression of heme oxygenase-1 and hepatitis C virus genes in human hepatocytes. Gastroenterology 2007; 133: 1166-74.
-
(2007)
Gastroenterology
, vol.133
, pp. 1166-1174
-
-
Shan, Y.1
Zheng, J.2
Lambrecht, R.W.3
-
120
-
-
58049217312
-
MicroRNA-122 stimulates translation of hepatitis C virus RNA
-
Henke JI, Goergen D, Zheng J, et al. MicroRNA-122 stimulates translation of hepatitis C virus RNA. EMBO J 2008; 27: 3300-10.
-
(2008)
EMBO J
, vol.27
, pp. 3300-3310
-
-
Henke, J.I.1
Goergen, D.2
Zheng, J.3
-
121
-
-
55849144769
-
Sustained delivery of siRNAs targeting viral infection by cell-degradable multilayered polyelectrolyte films
-
Dimitrova M, Affolter C, Meyer F, et al. Sustained delivery of siRNAs targeting viral infection by cell-degradable multilayered polyelectrolyte films. Proc Natl Acad Sci USA 2008; 105: 16320-5.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 16320-16325
-
-
Dimitrova, M.1
Affolter, C.2
Meyer, F.3
-
122
-
-
22544481160
-
Stealth and cunning: Hepatitis B and hepatitis C viruses
-
Wieland SF, Chisari FV. Stealth and cunning: hepatitis B and hepatitis C viruses. J Virol 2005; 79: 9369-80.
-
(2005)
J Virol
, vol.79
, pp. 9369-9380
-
-
Wieland, S.F.1
Chisari, F.V.2
-
123
-
-
17944379233
-
Hepatitis C virus replication in mice with chimeric human livers
-
Mercer DF, Schiller DE, Elliott JF, et al. Hepatitis C virus replication in mice with chimeric human livers. Nat Med 2001; 7: 927-933.
-
(2001)
Nat Med
, vol.7
, pp. 927-933
-
-
Mercer, D.F.1
Schiller, D.E.2
Elliott, J.F.3
-
124
-
-
34250020201
-
Hepatocellular carcinoma: Epidemiology and molecular carcinogenesis
-
El-Serag HB, Rudolph KL. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology 2007; 132: 2557-76.
-
(2007)
Gastroenterology
, vol.132
, pp. 2557-2576
-
-
El-Serag, H.B.1
Rudolph, K.L.2
-
125
-
-
33646564091
-
Adenovirus-mediated transfer of siRNA against PTTG1 inhibits liver cancer cell growth in vitro and in vivo
-
Cho-Rok J, Yoo J, Jang YJ, et al. Adenovirus-mediated transfer of siRNA against PTTG1 inhibits liver cancer cell growth in vitro and in vivo. Hepatology 2006; 43: 1042-52.
-
(2006)
Hepatology
, vol.43
, pp. 1042-1052
-
-
Cho-Rok, J.1
Yoo, J.2
Jang, Y.J.3
-
126
-
-
33845736472
-
RNA interference against urokinase in hepatocellular carcinoma xenografts in nude mice
-
Salvi A, Arici B, Alghisi A, et al. RNA interference against urokinase in hepatocellular carcinoma xenografts in nude mice. Tumour Biol 2007; 28: 16-26.
-
(2007)
Tumour Biol
, vol.28
, pp. 16-26
-
-
Salvi, A.1
Arici, B.2
Alghisi, A.3
-
127
-
-
4444233040
-
Small interfering RNA urokinase silencing inhibits invasion and migration of human hepatocellular carcinoma cells
-
Salvi A, Arici B, De Petro G, et al. Small interfering RNA urokinase silencing inhibits invasion and migration of human hepatocellular carcinoma cells. Mol Cancer Ther 2004; 3: 671-78.
-
(2004)
Mol Cancer Ther
, vol.3
, pp. 671-678
-
-
Salvi, A.1
Arici, B.2
De Petro, G.3
-
128
-
-
20444498521
-
Use of adenovirus-delivered siRNA to target oncoprotein p28GANK in hepatocellular carcinoma
-
Li H, Fu X, Chen Y, et al. Use of adenovirus-delivered siRNA to target oncoprotein p28GANK in hepatocellular carcinoma. Gastroenterology 2005; 128: 2029-41.
-
(2005)
Gastroenterology
, vol.128
, pp. 2029-2041
-
-
Li, H.1
Fu, X.2
Chen, Y.3
-
129
-
-
34748893835
-
Proteomic analysis of EZH2 downstream target proteins in hepatocellular carcinoma
-
Chen Y, Lin MC, Wang H, et al. Proteomic analysis of EZH2 downstream target proteins in hepatocellular carcinoma. Proteomics 2007; 7: 3097-104.
-
(2007)
Proteomics
, vol.7
, pp. 3097-3104
-
-
Chen, Y.1
Lin, M.C.2
Wang, H.3
-
131
-
-
17244377696
-
Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9
-
Rashid S, Curtis DE, Garuti R, et al. Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9. Proc Natl Acad Sci USA 2005; 102: 5374-9.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 5374-5379
-
-
Rashid, S.1
Curtis, D.E.2
Garuti, R.3
-
132
-
-
33645103550
-
Sequence variations in PCSK9, low LDL, and protection against coronary heart disease
-
Cohen JC, Boerwinkle E, Mosley TH, Jr., et al. Sequence variations in PCSK9, low LDL, and protection against coronary heart disease. N Engl J Med 2006; 354: 1264-72.
-
(2006)
N Engl J Med
, vol.354
, pp. 1264-1272
-
-
Cohen, J.C.1
Boerwinkle, E.2
Mosley Jr., T.H.3
-
133
-
-
0034723290
-
Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury
-
Friedman SL. Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury. J Biol Chem 2000; 275: 2247-50.
-
(2000)
J Biol Chem
, vol.275
, pp. 2247-2250
-
-
Friedman, S.L.1
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