New multivalent cationic lipids reveal bell curve for transfection efficiency versus membrane charge density: Lipid - DNA complexes for gene delivery

Journal of Gene Medicine

Volumn 7, Issue 6, 2005, Pages 739-748

  Ahmad, Ayesha ^a   Evans, Heather M ^a   Ewert, Kai ^a   George, Cyril X ^b   Samuel, Charles E ^b   Safinya, Cyrus R ^a  

^a University of California   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cationic lipids; Gene therapy; Membrane charge density; Transfection efficiency

Indexed keywords

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; DNA; ETHIDIUM BROMIDE; LIPID; LIPOSOME; LUCIFERASE;

ANIMAL CELL; ARTICLE; CELL DENSITY; CELL INTERACTION; CELL MEMBRANE; CONTROLLED STUDY; CYTOSOL; ENDOSOME; ENZYME ASSAY; FIBROBLAST; GENETIC TRANSFECTION; LIPID COMPOSITION; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; X RAY DIFFRACTION;

ANIMALS; CATIONS; DNA; FATTY ACIDS, MONOUNSATURATED; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENES, REPORTER; L CELLS (CELL LINE); LIPID BILAYERS; LIPOSOMES; LUCIFERASES; MICE; MODELS, BIOLOGICAL; MODELS, CHEMICAL; NORMAL DISTRIBUTION; PHOSPHATIDYLETHANOLAMINES; QUATERNARY AMMONIUM COMPOUNDS; TRANSFECTION; X-RAY DIFFRACTION;

EID: 12244291636     PISSN: 1099498X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jgm.717     Document Type: Article

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