Globin lentiviral vector insertions can perturb the expression of endogenous genes in β-thalassemic hematopoietic cells

Molecular Therapy

Volumn 16, Issue 3, 2008, Pages 525-533

  Hargrove, Phillip W ^a   Kepes, Steven ^a   Hanawa, Hideki ^b   Obenauer, John C ^a   Pei, Deiqing ^a   Cheng, Cheng ^a   Gray, John T ^a   Neale, Geoffrey ^a   Persons, Derek A ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b NIPPON MEDICAL SCHOOL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA GLOBIN; LENTIVIRUS VECTOR;

ANIMAL CELL; ARTICLE; BETA THALASSEMIA; CELL BASED GENE THERAPY; CLONING VECTOR; CONTROLLED STUDY; ENHANCER REGION; ERYTHROID CELL; GENE ACTIVATION; GENE EXPRESSION; GENE INACTIVATION; GENE INSERTION; HEMATOPOIETIC CELL; INCIDENCE; LONG TERMINAL REPEAT; MOUSE; NONHUMAN; PROSPECTIVE STUDY; REGULATOR GENE;

MURINAE;

EID: 39849094315     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/sj.mt.6300394     Document Type: Article

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