메뉴 건너뛰기




Volumn 83, Issue 4, 2009, Pages 297-318

Mammalian epoxide hydrolases in xenobiotic metabolism and signalling

Author keywords

ABHD; Cholesterol; EET; EPHX; Epoxide hydrolase; Lipid phosphatase; Lipid signalling; Peg1 MEST; Xenobiotic metabolism

Indexed keywords

1,3 BUTADIENE; CHOLESTEROL EPOXIDE HYDROLASE; DIMETHYLBENZ[A]ANTHRACENE; EPOXIDE HYDROLASE; EPOXIDE HYDROLASE 3; EPOXIDE HYDROLASE 4; HEPOXILIN EPOXIDE HYDROLASE; LEUKOTRIENE A4 HYDROLASE; LIPID; MICROSOMAL EPOXIDE HYDROLASE; SOLUBLE EPOXIDE HYDROLASE; STYRENE OXIDE; UNCLASSIFIED DRUG; VALPROMIDE;

EID: 64249112966     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-009-0416-0     Document Type: Article
Times cited : (173)

References (233)
  • 1
    • 34547468357 scopus 로고    scopus 로고
    • Angiotensin II up-regulates soluble epoxide hydrolase in vascular endothelium in vitro and in vivo
    • 10.1073/pnas.0703229104
    • D Ai Y Fu D Guo H Tanaka N Wang C Tang BD Hammock JY Shyy Y Zhu 2007 Angiotensin II up-regulates soluble epoxide hydrolase in vascular endothelium in vitro and in vivo Proc Natl Acad Sci USA 104 9018 9023 10.1073/pnas.0703229104
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 9018-9023
    • Ai, D.1    Fu, Y.2    Guo, D.3    Tanaka, H.4    Wang, N.5    Tang, C.6    Hammock, B.D.7    Shyy, J.Y.8    Zhu, Y.9
  • 3
    • 4344585269 scopus 로고    scopus 로고
    • Phosphoryl group transfer: Evolution of a catalytic scaffold
    • 10.1016/j.tibs.2004.07.008
    • KN Allen D Dunaway-Mariano 2004 Phosphoryl group transfer: evolution of a catalytic scaffold Trends Biochem Sci 29 495 503 10.1016/j.tibs.2004.07.008
    • (2004) Trends Biochem Sci , vol.29 , pp. 495-503
    • Allen, K.N.1    Dunaway-Mariano, D.2
  • 4
    • 0031898293 scopus 로고    scopus 로고
    • Occurrence of hepoxilins and trioxilins in psoriatic lesions
    • 10.1046/j.1523-1747.1998.00159.x
    • R Anton L Puig T Esgleyes JM de Moragas L Vila 1998 Occurrence of hepoxilins and trioxilins in psoriatic lesions J Invest Dermatol 110 303 310 10.1046/j.1523-1747.1998.00159.x
    • (1998) J Invest Dermatol , vol.110 , pp. 303-310
    • Anton, R.1    Puig, L.2    Esgleyes, T.3    De Moragas, J.M.4    Vila, L.5
  • 5
    • 0025935374 scopus 로고
    • An impaired peroxisomal targeting sequence leading to an unusual bicompartmental distribution of cytosolic epoxide hydrolase
    • 10.1016/0014-5793(91)81333-4
    • M Arand M Knehr H Thomas HD Zeller F Oesch 1991 An impaired peroxisomal targeting sequence leading to an unusual bicompartmental distribution of cytosolic epoxide hydrolase FEBS Lett 294 19 22 10.1016/0014-5793(91)81333-4
    • (1991) FEBS Lett , vol.294 , pp. 19-22
    • Arand, M.1    Knehr, M.2    Thomas, H.3    Zeller, H.D.4    Oesch, F.5
  • 6
    • 0028147334 scopus 로고
    • Sequence similarity of mammalian epoxide hydrolases to the bacterial haloalkane dehalogenase and other related proteins. Implication for the potential catalytic mechanism of enzymatic epoxide hydrolysis
    • 10.1016/0014-5793(94)80278-5
    • M Arand DF Grant JK Beetham T Friedberg F Oesch BD Hammock 1994 Sequence similarity of mammalian epoxide hydrolases to the bacterial haloalkane dehalogenase and other related proteins. Implication for the potential catalytic mechanism of enzymatic epoxide hydrolysis FEBS Lett 338 251 256 10.1016/0014-5793(94)80278-5
    • (1994) FEBS Lett , vol.338 , pp. 251-256
    • Arand, M.1    Grant, D.F.2    Beetham, J.K.3    Friedberg, T.4    Oesch, F.5    Hammock, B.D.6
  • 7
    • 0029664614 scopus 로고    scopus 로고
    • Asp333, Asp495, and His523 form the catalytic triad of rat soluble epoxide hydrolase
    • 10.1074/jbc.271.8.4223
    • M Arand H Wagner F Oesch 1996 Asp333, Asp495, and His523 form the catalytic triad of rat soluble epoxide hydrolase J Biol Chem 271 4223 4229 10.1074/jbc.271.8.4223
    • (1996) J Biol Chem , vol.271 , pp. 4223-4229
    • Arand, M.1    Wagner, H.2    Oesch, F.3
  • 8
    • 0033570996 scopus 로고    scopus 로고
    • Cloning and molecular characterization of a soluble epoxide hydrolase from Aspergillus niger that is related to mammalian microsomal epoxide hydrolase
    • 10.1042/0264-6021:3440273
    • M Arand H Hemmer H Durk J Baratti A Archelas R Furstoss F Oesch 1999 Cloning and molecular characterization of a soluble epoxide hydrolase from Aspergillus niger that is related to mammalian microsomal epoxide hydrolase Biochem J 344 Pt 1 273 280 10.1042/0264-6021:3440273
    • (1999) Biochem J , vol.344 , Issue.PT 1 , pp. 273-280
    • Arand, M.1    Hemmer, H.2    Durk, H.3    Baratti, J.4    Archelas, A.5    Furstoss, R.6    Oesch, F.7
  • 9
    • 2442731907 scopus 로고    scopus 로고
    • Catalytic triad of microsomal epoxide hydrolase: Replacement of Glu404 with Asp leads to a strongly increased turnover rate
    • 10.1042/0264-6021:3370037
    • M Arand F Muller A Mecky W Hinz P Urban D Pompon R Kellner F Oesch 1999 Catalytic triad of microsomal epoxide hydrolase: replacement of Glu404 with Asp leads to a strongly increased turnover rate Biochem J 337 Pt 1 37 43 10.1042/0264-6021:3370037
    • (1999) Biochem J , vol.337 , Issue.PT 1 , pp. 37-43
    • Arand, M.1    Muller, F.2    Mecky, A.3    Hinz, W.4    Urban, P.5    Pompon, D.6    Kellner, R.7    Oesch, F.8
  • 12
    • 0038030990 scopus 로고    scopus 로고
    • Detoxification strategy of epoxide hydrolase-the basis for a threshold in chemical carcinogenesis
    • M Arand ME Herrero Plana JG Hengstler M Lohmann A Cronin F Oesch 2003 Detoxification strategy of epoxide hydrolase-the basis for a threshold in chemical carcinogenesis EXCLI J 2 22 30
    • (2003) EXCLI J , vol.2 , pp. 22-30
    • Arand, M.1    Herrero Plana, M.E.2    Hengstler, J.G.3    Lohmann, M.4    Cronin, A.5    Oesch, F.6
  • 13
    • 0032849109 scopus 로고    scopus 로고
    • Detoxification of environmental mutagens and carcinogens: Structure, mechanism, and evolution of liver epoxide hydrolase
    • 10.1073/pnas.96.19.10637
    • MA Argiriadi C Morisseau BD Hammock DW Christianson 1999 Detoxification of environmental mutagens and carcinogens: structure, mechanism, and evolution of liver epoxide hydrolase Proc Natl Acad Sci USA 96 10637 10642 10.1073/pnas.96.19.10637
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 10637-10642
    • Argiriadi, M.A.1    Morisseau, C.2    Hammock, B.D.3    Christianson, D.W.4
  • 14
    • 0016230887 scopus 로고
    • Formation and metabolism in vitro of 5, 6-epoxides of cholesterol and beta-sitosterol
    • L Aringer P Eneroth 1974 Formation and metabolism in vitro of 5, 6-epoxides of cholesterol and beta-sitosterol J Lipid Res 15 389 398
    • (1974) J Lipid Res , vol.15 , pp. 389-398
    • Aringer, L.1    Eneroth, P.2
  • 15
    • 0023084762 scopus 로고
    • Enzyme-catalyzed detoxication reactions: Mechanisms and stereochemistry
    • 10.3109/10409238709082547
    • RN Armstrong 1987 Enzyme-catalyzed detoxication reactions: mechanisms and stereochemistry CRC Crit Rev Biochem 22 39 88 10.3109/10409238709082547
    • (1987) CRC Crit Rev Biochem , vol.22 , pp. 39-88
    • Armstrong, R.N.1
  • 16
    • 0034538911 scopus 로고    scopus 로고
    • New structural and chemical insight into the catalytic mechanism of epoxide hydrolases
    • 10.1081/DMR-100102337
    • RN Armstrong CS Cassidy 2000 New structural and chemical insight into the catalytic mechanism of epoxide hydrolases Drug Metab Rev 32 327 338 10.1081/DMR-100102337
    • (2000) Drug Metab Rev , vol.32 , pp. 327-338
    • Armstrong, R.N.1    Cassidy, C.S.2
  • 18
    • 0023089151 scopus 로고
    • Induction of liver microsomal epoxide hydrolase, UDP-glucuronyl transferase and cytosolic glutathione transferase in different rodent species by 2-acetylaminofluorene or 3-methylcholanthrene
    • A Astrom S Maner JW DePierre 1987 Induction of liver microsomal epoxide hydrolase, UDP-glucuronyl transferase and cytosolic glutathione transferase in different rodent species by 2-acetylaminofluorene or 3-methylcholanthrene Xenobiotica 17 155 163
    • (1987) Xenobiotica , vol.17 , pp. 155-163
    • Astrom, A.1    Maner, S.2    Depierre, J.W.3
  • 19
    • 0032581010 scopus 로고    scopus 로고
    • Insights into the mechanism of catalysis by the P-C bond-cleaving enzyme phosphonoacetaldehyde hydrolase derived from gene sequence analysis and mutagenesis
    • 10.1021/bi972677d
    • AS Baker MJ Ciocci WW Metcalf J Kim PC Babbitt BL Wanner BM Martin D Dunaway-Mariano 1998 Insights into the mechanism of catalysis by the P-C bond-cleaving enzyme phosphonoacetaldehyde hydrolase derived from gene sequence analysis and mutagenesis Biochemistry 37 9305 9315 10.1021/bi972677d
    • (1998) Biochemistry , vol.37 , pp. 9305-9315
    • Baker, A.S.1    Ciocci, M.J.2    Metcalf, W.W.3    Kim, J.4    Babbitt, P.C.5    Wanner, B.L.6    Martin, B.M.7    Dunaway-Mariano, D.8
  • 20
    • 0031767358 scopus 로고    scopus 로고
    • The Rhodococcus erythropolis DCL14 limonene-1, 2-epoxide hydrolase gene encodes an enzyme belonging to a novel class of epoxide hydrolases
    • 10.1016/S0014-5793(98)01322-2
    • F Barbirato JC Verdoes JA de Bont MJ van der Werf 1998 The Rhodococcus erythropolis DCL14 limonene-1, 2-epoxide hydrolase gene encodes an enzyme belonging to a novel class of epoxide hydrolases FEBS Lett 438 293 296 10.1016/S0014-5793(98)01322-2
    • (1998) FEBS Lett , vol.438 , pp. 293-296
    • Barbirato, F.1    Verdoes, J.C.2    De Bont, J.A.3    Van Der Werf, M.J.4
  • 21
    • 0027219730 scopus 로고
    • CDNA cloning and expression of a soluble epoxide hydrolase from human liver
    • 10.1006/abbi.1993.1411
    • JK Beetham T Tian BD Hammock 1993 cDNA cloning and expression of a soluble epoxide hydrolase from human liver Arch Biochem Biophys 305 197 201 10.1006/abbi.1993.1411
    • (1993) Arch Biochem Biophys , vol.305 , pp. 197-201
    • Beetham, J.K.1    Tian, T.2    Hammock, B.D.3
  • 23
    • 0023243261 scopus 로고
    • The metabolism of carbamazepine in humans: Steric course of the enzymatic hydrolysis of the 10, 11-epoxide
    • 10.1021/jm00388a004
    • G Bellucci G Berti C Chiappe A Lippi F Marioni 1987 The metabolism of carbamazepine in humans: steric course of the enzymatic hydrolysis of the 10, 11-epoxide J Med Chem 30 768 773 10.1021/jm00388a004
    • (1987) J Med Chem , vol.30 , pp. 768-773
    • Bellucci, G.1    Berti, G.2    Chiappe, C.3    Lippi, A.4    Marioni, F.5
  • 24
    • 0017081030 scopus 로고
    • Epoxides derived from various polycyclic hydrocarbons as substrates of homogeneous and microsome-bound epoxide hydratase. A general assay and kinetic properties
    • 10.1111/j.1432-1033.1976.tb10862.x
    • P Bentley H Schmassmann P Sims F Oesch 1976 Epoxides derived from various polycyclic hydrocarbons as substrates of homogeneous and microsome-bound epoxide hydratase. A general assay and kinetic properties Eur J Biochem 69 97 103 10.1111/j.1432-1033.1976.tb10862.x
    • (1976) Eur J Biochem , vol.69 , pp. 97-103
    • Bentley, P.1    Schmassmann, H.2    Sims, P.3    Oesch, F.4
  • 25
    • 0015444422 scopus 로고
    • A model system for the evaluation of the role of cholesterol-oxide in ultraviolet carcinogenesis
    • HS Black DR Douglas 1972 A model system for the evaluation of the role of cholesterol-oxide in ultraviolet carcinogenesis Cancer Res 32 2630 2632
    • (1972) Cancer Res , vol.32 , pp. 2630-2632
    • Black, H.S.1    Douglas, D.R.2
  • 26
    • 34447315030 scopus 로고    scopus 로고
    • The hepoxilin connection in the epidermis
    • 10.1111/j.1742-4658.2007.05909.x
    • AR Brash Z Yu WE Boeglin C Schneider 2007 The hepoxilin connection in the epidermis FEBS J 274 3494 3502 10.1111/j.1742-4658.2007.05909.x
    • (2007) FEBS J , vol.274 , pp. 3494-3502
    • Brash, A.R.1    Yu, Z.2    Boeglin, W.E.3    Schneider, C.4
  • 27
    • 33750094349 scopus 로고    scopus 로고
    • Genetic association between COPD and polymorphisms in TNF, ADRB2 and EPHX1
    • 10.1183/09031936.06.00057005
    • J Brogger VM Steen HG Eiken A Gulsvik P Bakke 2006 Genetic association between COPD and polymorphisms in TNF, ADRB2 and EPHX1 Eur Respir J 27 682 688 10.1183/09031936.06.00057005
    • (2006) Eur Respir J , vol.27 , pp. 682-688
    • Brogger, J.1    Steen, V.M.2    Eiken, H.G.3    Gulsvik, A.4    Bakke, P.5
  • 28
  • 29
    • 0017106090 scopus 로고
    • Distribution of cholesterol-5alpha, 6alpha-epoxide formation and its metabolism in mouse skin
    • 10.1111/1523-1747.ep12481460
    • JT Chan HS Black 1976 Distribution of cholesterol-5alpha, 6alpha-epoxide formation and its metabolism in mouse skin J Invest Dermatol 66 112 116 10.1111/1523-1747.ep12481460
    • (1976) J Invest Dermatol , vol.66 , pp. 112-116
    • Chan, J.T.1    Black, H.S.2
  • 30
    • 2342421274 scopus 로고    scopus 로고
    • Leukotriene A4 hydrolase as a target for cancer prevention and therapy
    • 10.2174/1568009043333041
    • X Chen S Wang N Wu CS Yang 2004 Leukotriene A4 hydrolase as a target for cancer prevention and therapy Curr Cancer Drug Targets 4 267 283 10.2174/1568009043333041
    • (2004) Curr Cancer Drug Targets , vol.4 , pp. 267-283
    • Chen, X.1    Wang, S.2    Wu, N.3    Yang, C.S.4
  • 31
    • 0035175179 scopus 로고    scopus 로고
    • Distribution of microsomal epoxide hydrolase in humans: An immunohistochemical study in normal tissues, and benign and malignant tumours
    • 10.1023/A:1012414806166
    • JK Coller P Fritz UM Zanger I Siegle M Eichelbaum HK Kroemer TE Murdter 2001 Distribution of microsomal epoxide hydrolase in humans: an immunohistochemical study in normal tissues, and benign and malignant tumours Histochem J 33 329 336 10.1023/A:1012414806166
    • (2001) Histochem J , vol.33 , pp. 329-336
    • Coller, J.K.1    Fritz, P.2    Zanger, U.M.3    Siegle, I.4    Eichelbaum, M.5    Kroemer, H.K.6    Murdter, T.E.7
  • 34
    • 52949126685 scopus 로고    scopus 로고
    • Insights into the catalytic mechanism of human sEH phosphatase by site-directed mutagenesis and LC-MS/MS analysis
    • 10.1016/j.jmb.2008.08.049
    • A Cronin S Homburg H Durk I Richter M Adamska F Frere M Arand 2008 Insights into the catalytic mechanism of human sEH phosphatase by site-directed mutagenesis and LC-MS/MS analysis J Mol Biol 383 627 640 10.1016/j.jmb.2008.08. 049
    • (2008) J Mol Biol , vol.383 , pp. 627-640
    • Cronin, A.1    Homburg, S.2    Durk, H.3    Richter, I.4    Adamska, M.5    Frere, F.6    Arand, M.7
  • 35
    • 0037452416 scopus 로고    scopus 로고
    • A toxicokinetic model for styrene and its metabolite styrene-7, 8-oxide in mouse, rat and human with special emphasis on the lung
    • 10.1016/S0378-4274(02)00409-5
    • GA Csanady W Kessler HD Hoffmann JG Filser 2003 A toxicokinetic model for styrene and its metabolite styrene-7, 8-oxide in mouse, rat and human with special emphasis on the lung Toxicol Lett 138 75 102 10.1016/S0378-4274(02) 00409-5
    • (2003) Toxicol Lett , vol.138 , pp. 75-102
    • Csanady, G.A.1    Kessler, W.2    Hoffmann, H.D.3    Filser, J.G.4
  • 37
    • 0021669273 scopus 로고
    • Hepoxilin A, hydroxyepoxide metabolite of arachidonic acid, stimulates transport of 45Ca across the guinea pig visceral yolk sac
    • LO Derewlany CR Pace-Asciak IC Radde 1984 Hepoxilin A, hydroxyepoxide metabolite of arachidonic acid, stimulates transport of 45Ca across the guinea pig visceral yolk sac Can J Physiol Pharmacol 62 1466 1469
    • (1984) Can J Physiol Pharmacol , vol.62 , pp. 1466-1469
    • Derewlany, L.O.1    Pace-Asciak, C.R.2    Radde, I.C.3
  • 38
    • 0025820693 scopus 로고
    • Inhibition of cytosolic epoxide hydrolase by trans-3-phenylglycidols
    • 10.1016/0006-2952(91)90250-9
    • EC Dietze E Kuwano J Casas BD Hammock 1991 Inhibition of cytosolic epoxide hydrolase by trans-3-phenylglycidols Biochem Pharmacol 42 1163 1175 10.1016/0006-2952(91)90250-9
    • (1991) Biochem Pharmacol , vol.42 , pp. 1163-1175
    • Dietze, E.C.1    Kuwano, E.2    Casas, J.3    Hammock, B.D.4
  • 40
    • 30144442298 scopus 로고    scopus 로고
    • Implications for an ionized alkyl-enzyme intermediate during StEH1-catalyzed trans-stilbene oxide hydrolysis
    • 10.1021/bi051893g
    • LT Elfstrom M Widersten 2006 Implications for an ionized alkyl-enzyme intermediate during StEH1-catalyzed trans-stilbene oxide hydrolysis Biochemistry 45 205 212 10.1021/bi051893g
    • (2006) Biochemistry , vol.45 , pp. 205-212
    • Elfstrom, L.T.1    Widersten, M.2
  • 41
    • 1842430562 scopus 로고    scopus 로고
    • Distribution of soluble epoxide hydrolase and of cytochrome P450 2C8, 2C9, and 2J2 in human tissues
    • AE Enayetallah RA French MS Thibodeau DF Grant 2004 Distribution of soluble epoxide hydrolase and of cytochrome P450 2C8, 2C9, and 2J2 in human tissues J Histochem Cytochem 52 447 454
    • (2004) J Histochem Cytochem , vol.52 , pp. 447-454
    • Enayetallah, A.E.1    French, R.A.2    Thibodeau, M.S.3    Grant, D.F.4
  • 42
    • 30944463775 scopus 로고    scopus 로고
    • Effects of human soluble epoxide hydrolase polymorphisms on isoprenoid phosphate hydrolysis
    • 10.1016/j.bbrc.2005.12.180
    • AE Enayetallah DF Grant 2006 Effects of human soluble epoxide hydrolase polymorphisms on isoprenoid phosphate hydrolysis Biochem Biophys Res Commun 341 254 260 10.1016/j.bbrc.2005.12.180
    • (2006) Biochem Biophys Res Commun , vol.341 , pp. 254-260
    • Enayetallah, A.E.1    Grant, D.F.2
  • 43
    • 33344460020 scopus 로고    scopus 로고
    • Cell-specific subcellular localization of soluble epoxide hydrolase in human tissues
    • 10.1369/jhc.5A6808.2005
    • AE Enayetallah RA French M Barber DF Grant 2006 Cell-specific subcellular localization of soluble epoxide hydrolase in human tissues J Histochem Cytochem 54 329 335 10.1369/jhc.5A6808.2005
    • (2006) J Histochem Cytochem , vol.54 , pp. 329-335
    • Enayetallah, A.E.1    French, R.A.2    Barber, M.3    Grant, D.F.4
  • 44
    • 39449097368 scopus 로고    scopus 로고
    • Distribution of soluble epoxide hydrolase, cytochrome P450 2C8, 2C9 and 2J2 in human malignant neoplasms
    • 10.1007/s10735-006-9050-9
    • AE Enayetallah RA French DF Grant 2006 Distribution of soluble epoxide hydrolase, cytochrome P450 2C8, 2C9 and 2J2 in human malignant neoplasms J Mol Histol 37 133 141 10.1007/s10735-006-9050-9
    • (2006) J Mol Histol , vol.37 , pp. 133-141
    • Enayetallah, A.E.1    French, R.A.2    Grant, D.F.3
  • 46
    • 0021868160 scopus 로고
    • Purification and characterisation of leukotriene A4 hydrolase from rat neutrophils
    • JF Evans P Dupuis AW Ford-Hutchinson 1985 Purification and characterisation of leukotriene A4 hydrolase from rat neutrophils Biochim Biophys Acta 840 43 50
    • (1985) Biochim Biophys Acta , vol.840 , pp. 43-50
    • Evans, J.F.1    Dupuis, P.2    Ford-Hutchinson, A.W.3
  • 47
    • 0023664359 scopus 로고
    • Structure and organization of the microsomal xenobiotic epoxide hydrolase gene
    • CN Falany P [tmp] McQuiddy CB Kasper 1987 Structure and organization of the microsomal xenobiotic epoxide hydrolase gene J Biol Chem 262 5924 5930
    • (1987) J Biol Chem , vol.262 , pp. 5924-5930
    • Falany, C.N.1    McQuiddy, P.2    Kasper, C.B.3
  • 49
    • 0028916408 scopus 로고
    • Induction of rat liver microsomal epoxide hydrolase by its endogenous substrate 16 alpha, 17 alpha-epoxyestra-1, 3, 5-trien-3-ol
    • F Fandrich B Degiuli U Vogel-Bindel M Arand F Oesch 1995 Induction of rat liver microsomal epoxide hydrolase by its endogenous substrate 16 alpha, 17 alpha-epoxyestra-1, 3, 5-trien-3-ol Xenobiotica 25 239 244
    • (1995) Xenobiotica , vol.25 , pp. 239-244
    • Fandrich, F.1    Degiuli, B.2    Vogel-Bindel, U.3    Arand, M.4    Oesch, F.5
  • 50
    • 39049098184 scopus 로고    scopus 로고
    • Soluble epoxide hydrolase: A novel target for the treatment of hypertension
    • X Fang 2006 Soluble epoxide hydrolase: a novel target for the treatment of hypertension Recent Pat Cardiovasc Drug Discov 1 67 72
    • (2006) Recent Pat Cardiovasc Drug Discov , vol.1 , pp. 67-72
    • Fang, X.1
  • 51
    • 0035805539 scopus 로고    scopus 로고
    • Pathways of epoxyeicosatrienoic acid metabolism in endothelial cells. Implications for the vascular effects of soluble epoxide hydrolase inhibition
    • 10.1074/jbc.M011761200
    • X Fang TL Kaduce NL Weintraub S Harmon LM Teesch C Morisseau DA Thompson BD Hammock AA Spector 2001 Pathways of epoxyeicosatrienoic acid metabolism in endothelial cells. Implications for the vascular effects of soluble epoxide hydrolase inhibition J Biol Chem 276 14867 14874 10.1074/jbc.M011761200
    • (2001) J Biol Chem , vol.276 , pp. 14867-14874
    • Fang, X.1    Kaduce, T.L.2    Weintraub, N.L.3    Harmon, S.4    Teesch, L.M.5    Morisseau, C.6    Thompson, D.A.7    Hammock, B.D.8    Spector, A.A.9
  • 52
    • 0346365077 scopus 로고    scopus 로고
    • Mechanistic diversity of fosfomycin resistance in pathogenic microorganisms
    • 10.1021/ja039307z
    • KL Fillgrove S Pakhomova ME Newcomer RN Armstrong 2003 Mechanistic diversity of fosfomycin resistance in pathogenic microorganisms J Am Chem Soc 125 15730 15731 10.1021/ja039307z
    • (2003) J Am Chem Soc , vol.125 , pp. 15730-15731
    • Fillgrove, K.L.1    Pakhomova, S.2    Newcomer, M.E.3    Armstrong, R.N.4
  • 53
    • 0023780585 scopus 로고
    • Increased cholesterol epoxide hydrolase activity in clofibrate-fed animals
    • 10.1016/0006-2952(88)90316-4
    • BL Finley BD Hammock 1988 Increased cholesterol epoxide hydrolase activity in clofibrate-fed animals Biochem Pharmacol 37 3169 3175 10.1016/0006-2952(88)90316-4
    • (1988) Biochem Pharmacol , vol.37 , pp. 3169-3175
    • Finley, B.L.1    Hammock, B.D.2
  • 55
    • 1642458135 scopus 로고    scopus 로고
    • Polymorphism of the soluble epoxide hydrolase is associated with coronary artery calcification in African-American subjects: The Coronary Artery Risk Development in Young Adults (CARDIA) study
    • 10.1161/01.CIR.0000109487.46725.02
    • M Fornage E Boerwinkle PA Doris D Jacobs K Liu ND Wong 2004 Polymorphism of the soluble epoxide hydrolase is associated with coronary artery calcification in African-American subjects: The Coronary Artery Risk Development in Young Adults (CARDIA) study Circulation 109 335 339 10.1161/01.CIR. 0000109487.46725.02
    • (2004) Circulation , vol.109 , pp. 335-339
    • Fornage, M.1    Boerwinkle, E.2    Doris, P.A.3    Jacobs, D.4    Liu, K.5    Wong, N.D.6
  • 56
    • 0025734772 scopus 로고
    • Crystal structure of haloalkane dehalogenase: An enzyme to detoxify halogenated alkanes
    • SM Franken HJ Rozeboom KH Kalk BW Dijkstra 1991 Crystal structure of haloalkane dehalogenase: an enzyme to detoxify halogenated alkanes EMBO J 10 1297 1302
    • (1991) EMBO J , vol.10 , pp. 1297-1302
    • Franken, S.M.1    Rozeboom, H.J.2    Kalk, K.H.3    Dijkstra, B.W.4
  • 57
    • 0028178824 scopus 로고
    • Studies on the importance of microsomal epoxide hydrolase in the detoxification of arene oxides using the heterologous expression of the enzyme in mammalian cells
    • 10.1093/carcin/15.2.171
    • T Friedberg R Becker F Oesch H Glatt 1994 Studies on the importance of microsomal epoxide hydrolase in the detoxification of arene oxides using the heterologous expression of the enzyme in mammalian cells Carcinogenesis 15 171 175 10.1093/carcin/15.2.171
    • (1994) Carcinogenesis , vol.15 , pp. 171-175
    • Friedberg, T.1    Becker, R.2    Oesch, F.3    Glatt, H.4
  • 58
    • 0028006636 scopus 로고
    • The microsomal epoxide hydrolase has a single membrane signal anchor sequence which is dispensable for the catalytic activity of this protein
    • T Friedberg B Lollmann R Becker R Holler F Oesch 1994 The microsomal epoxide hydrolase has a single membrane signal anchor sequence which is dispensable for the catalytic activity of this protein Biochem J 303 Pt 3 967 972
    • (1994) Biochem J , vol.303 , Issue.PT 3 , pp. 967-972
    • Friedberg, T.1    Lollmann, B.2    Becker, R.3    Holler, R.4    Oesch, F.5
  • 60
    • 33745728166 scopus 로고    scopus 로고
    • Silencing of Peroxiredoxin 2 and aberrant methylation of 33 CpG islands in putative promoter regions in human malignant melanomas
    • 10.1158/0008-5472.CAN-06-0157
    • J Furuta Y Nobeyama Y Umebayashi F Otsuka K Kikuchi T Ushijima 2006 Silencing of Peroxiredoxin 2 and aberrant methylation of 33 CpG islands in putative promoter regions in human malignant melanomas Cancer Res 66 6080 6086 10.1158/0008-5472.CAN-06-0157
    • (2006) Cancer Res , vol.66 , pp. 6080-6086
    • Furuta, J.1    Nobeyama, Y.2    Umebayashi, Y.3    Otsuka, F.4    Kikuchi, K.5    Ushijima, T.6
  • 61
    • 0031452319 scopus 로고    scopus 로고
    • Tissue-specific expression and alternative splicing of human microsomal epoxide hydrolase
    • A Gaedigk JS Leeder DM Grant 1997 Tissue-specific expression and alternative splicing of human microsomal epoxide hydrolase DNA Cell Biol 16 1257 1266
    • (1997) DNA Cell Biol , vol.16 , pp. 1257-1266
    • Gaedigk, A.1    Leeder, J.S.2    Grant, D.M.3
  • 62
    • 34447540174 scopus 로고    scopus 로고
    • Microsomal expoxide hydrolase is required for 7, 12-dimethylbenz[a] anthracene (DMBA)-induced immunotoxicity in mice
    • 10.1093/toxsci/kfm089
    • J Gao FT Lauer LA Mitchell SW Burchiel 2007 Microsomal expoxide hydrolase is required for 7, 12-dimethylbenz[a]anthracene (DMBA)-induced immunotoxicity in mice Toxicol Sci 98 137 144 10.1093/toxsci/kfm089
    • (2007) Toxicol Sci , vol.98 , pp. 137-144
    • Gao, J.1    Lauer, F.T.2    Mitchell, L.A.3    Burchiel, S.W.4
  • 63
    • 1942438591 scopus 로고    scopus 로고
    • Structure of human epoxide hydrolase reveals mechanistic inferences on bifunctional catalysis in epoxide and phosphate ester hydrolysis
    • 10.1021/bi036189j
    • GA Gomez C Morisseau BD Hammock DW Christianson 2004 Structure of human epoxide hydrolase reveals mechanistic inferences on bifunctional catalysis in epoxide and phosphate ester hydrolysis Biochemistry 43 4716 4723 10.1021/bi036189j
    • (2004) Biochemistry , vol.43 , pp. 4716-4723
    • Gomez, G.A.1    Morisseau, C.2    Hammock, B.D.3    Christianson, D.W.4
  • 64
    • 0019888054 scopus 로고
    • Cloning of epoxide hydratase complementary DNA
    • FJ Gonzalez CB Kasper 1981 Cloning of epoxide hydratase complementary DNA J Biol Chem 256 4697 4700
    • (1981) J Biol Chem , vol.256 , pp. 4697-4700
    • Gonzalez, F.J.1    Kasper, C.B.2
  • 65
    • 0027171486 scopus 로고
    • Molecular cloning and expression of murine liver soluble epoxide hydrolase
    • DF Grant DH Storms BD Hammock 1993 Molecular cloning and expression of murine liver soluble epoxide hydrolase J Biol Chem 268 17628 17633
    • (1993) J Biol Chem , vol.268 , pp. 17628-17633
    • Grant, D.F.1    Storms, D.H.2    Hammock, B.D.3
  • 66
    • 0026759504 scopus 로고
    • Opioid peptides are substrates for the bifunctional enzyme LTA4 hydrolase/aminopeptidase
    • 10.1016/0090-6980(92)90018-O
    • KJ Griffin J Gierse G Krivi FA Fitzpatrick 1992 Opioid peptides are substrates for the bifunctional enzyme LTA4 hydrolase/aminopeptidase Prostaglandins 44 251 257 10.1016/0090-6980(92)90018-O
    • (1992) Prostaglandins , vol.44 , pp. 251-257
    • Griffin, K.J.1    Gierse, J.2    Krivi, G.3    Fitzpatrick, F.A.4
  • 67
    • 44449110695 scopus 로고    scopus 로고
    • Genetic variation in soluble epoxide hydrolase (EPHX2) is associated with an increased risk of ischemic stroke in white Europeans
    • 10.1161/STROKEAHA.107.502179
    • A Gschwendtner S Ripke T Freilinger P Lichtner B Muller-Myhsok HE Wichmann T Meitinger M Dichgans 2008 Genetic variation in soluble epoxide hydrolase (EPHX2) is associated with an increased risk of ischemic stroke in white Europeans Stroke 39 1593 1596 10.1161/STROKEAHA.107.502179
    • (2008) Stroke , vol.39 , pp. 1593-1596
    • Gschwendtner, A.1    Ripke, S.2    Freilinger, T.3    Lichtner, P.4    Muller-Myhsok, B.5    Wichmann, H.E.6    Meitinger, T.7    Dichgans, M.8
  • 69
    • 8444231353 scopus 로고    scopus 로고
    • Combined analysis of polymorphisms in glutathione S-transferase M1 and microsomal epoxide hydrolase in lung cancer patients
    • V Habalova J Salagovic I Kalina J Stubna 2004 Combined analysis of polymorphisms in glutathione S-transferase M1 and microsomal epoxide hydrolase in lung cancer patients Neoplasma 51 352 357
    • (2004) Neoplasma , vol.51 , pp. 352-357
    • Habalova, V.1    Salagovic, J.2    Kalina, I.3    Stubna, J.4
  • 70
    • 10944253095 scopus 로고    scopus 로고
    • Leukotriene A4 hydrolase/aminopeptidase, the gatekeeper of chemotactic leukotriene B4 biosynthesis
    • 10.1074/jbc.R400027200
    • JZ Haeggstrom 2004 Leukotriene A4 hydrolase/aminopeptidase, the gatekeeper of chemotactic leukotriene B4 biosynthesis J Biol Chem 279 50639 50642 10.1074/jbc.R400027200
    • (2004) J Biol Chem , vol.279 , pp. 50639-50642
    • Haeggstrom, J.Z.1
  • 71
    • 0025572226 scopus 로고
    • Leukotriene A4 hydrolase: An epoxide hydrolase with peptidase activity
    • 10.1016/S0006-291X(05)81076-9
    • JZ Haeggstrom A Wetterholm BL Vallee B Samuelsson 1990 Leukotriene A4 hydrolase: an epoxide hydrolase with peptidase activity Biochem Biophys Res Commun 173 431 437 10.1016/S0006-291X(05)81076-9
    • (1990) Biochem Biophys Res Commun , vol.173 , pp. 431-437
    • Haeggstrom, J.Z.1    Wetterholm, A.2    Vallee, B.L.3    Samuelsson, B.4
  • 73
    • 34247465008 scopus 로고    scopus 로고
    • Structure and catalytic mechanisms of leukotriene A4 hydrolase
    • 10.1016/j.prostaglandins.2007.01.006
    • JZ Haeggstrom F Tholander A Wetterholm 2007 Structure and catalytic mechanisms of leukotriene A4 hydrolase Prostaglandins Other Lipid Mediat 83 198 202 10.1016/j.prostaglandins.2007.01.006
    • (2007) Prostaglandins Other Lipid Mediat , vol.83 , pp. 198-202
    • Haeggstrom, J.Z.1    Tholander, F.2    Wetterholm, A.3
  • 74
    • 40949103437 scopus 로고    scopus 로고
    • Identification of two epoxide hydrolases in Caenorhabditis elegans that metabolize mammalian lipid signaling molecules
    • Harris TR, Aronov PA, Jones PD, Tanaka H, Arand M, Hammock BD (2008) Identification of two epoxide hydrolases in Caenorhabditis elegans that metabolize mammalian lipid signaling molecules. Arch Biochem Biophys
    • (2008) Arch Biochem Biophys
    • Harris, T.R.1    Aronov, P.A.2    Jones, P.D.3    Tanaka, H.4    Arand, M.5    Hammock, B.D.6
  • 75
    • 0024311510 scopus 로고
    • Rabbit microsomal epoxide hydrolase: Isolation and characterization of the xenobiotic metabolizing enzyme cDNA
    • 10.1016/0003-9861(89)90287-7
    • C Hassett SM Turnblom A DeAngeles CJ Omiecinski 1989 Rabbit microsomal epoxide hydrolase: isolation and characterization of the xenobiotic metabolizing enzyme cDNA Arch Biochem Biophys 271 380 389 10.1016/0003-9861(89)90287-7
    • (1989) Arch Biochem Biophys , vol.271 , pp. 380-389
    • Hassett, C.1    Turnblom, S.M.2    Deangeles, A.3    Omiecinski, C.J.4
  • 76
    • 0028295652 scopus 로고
    • Human microsomal epoxide hydrolase: Genetic polymorphism and functional expression in vitro of amino acid variants
    • 10.1093/hmg/3.3.421
    • C Hassett L Aicher JS Sidhu CJ Omiecinski 1994 Human microsomal epoxide hydrolase: genetic polymorphism and functional expression in vitro of amino acid variants Hum Mol Genet 3 421 428 10.1093/hmg/3.3.421
    • (1994) Hum Mol Genet , vol.3 , pp. 421-428
    • Hassett, C.1    Aicher, L.2    Sidhu, J.S.3    Omiecinski, C.J.4
  • 77
    • 0031568236 scopus 로고    scopus 로고
    • Human hepatic microsomal epoxide hydrolase: Comparative analysis of polymorphic expression
    • 10.1006/abbi.1996.9794
    • C Hassett J Lin CL Carty EM Laurenzana CJ Omiecinski 1997 Human hepatic microsomal epoxide hydrolase: comparative analysis of polymorphic expression Arch Biochem Biophys 337 275 283 10.1006/abbi.1996.9794
    • (1997) Arch Biochem Biophys , vol.337 , pp. 275-283
    • Hassett, C.1    Lin, J.2    Carty, C.L.3    Laurenzana, E.M.4    Omiecinski, C.J.5
  • 78
    • 0032235209 scopus 로고    scopus 로고
    • Polymorphisms of N-acetyltransferases, glutathione S-transferases, microsomal epoxide hydrolase and sulfotransferases: Influence on cancer susceptibility
    • JG Hengstler M Arand ME Herrero F Oesch 1998 Polymorphisms of N-acetyltransferases, glutathione S-transferases, microsomal epoxide hydrolase and sulfotransferases: influence on cancer susceptibility Recent Results Cancer Res 154 47 85
    • (1998) Recent Results Cancer Res , vol.154 , pp. 47-85
    • Hengstler, J.G.1    Arand, M.2    Herrero, M.E.3    Oesch, F.4
  • 80
    • 0031416480 scopus 로고    scopus 로고
    • Recombinant expression of human microsomal epoxide hydrolase protects V79 Chinese hamster cells from styrene oxide-but not from ethylene oxide-induced DNA strand breaks
    • 10.1002/(SICI)1098-2280(1997)30:4<429::AID-EM8>3.0.CO;2-D
    • ME Herrero M Arand JG Hengstler F Oesch 1997 Recombinant expression of human microsomal epoxide hydrolase protects V79 Chinese hamster cells from styrene oxide-but not from ethylene oxide-induced DNA strand breaks Environ Mol Mutagen 30 429 439 10.1002/(SICI)1098-2280(1997)30:4<429::AID-EM8>3.0. CO;2-D
    • (1997) Environ Mol Mutagen , vol.30 , pp. 429-439
    • Herrero, M.E.1    Arand, M.2    Hengstler, J.G.3    Oesch, F.4
  • 81
    • 0000275596 scopus 로고
    • Effects of inducers and epoxide hydrase on the metabolism of benzo[a]pyrene by liver microsomes and a reconstituted system: Analysis by high pressure liquid chromatography
    • 10.1073/pnas.71.11.4356
    • G Holder H Yagi P Dansette DM Jerina W Levin AY Lu AH Conney 1974 Effects of inducers and epoxide hydrase on the metabolism of benzo[a]pyrene by liver microsomes and a reconstituted system: analysis by high pressure liquid chromatography Proc Natl Acad Sci USA 71 4356 4360 10.1073/pnas.71.11.4356
    • (1974) Proc Natl Acad Sci USA , vol.71 , pp. 4356-4360
    • Holder, G.1    Yagi, H.2    Dansette, P.3    Jerina, D.M.4    Levin, W.5    Lu, A.Y.6    Conney, A.H.7
  • 82
    • 0031591680 scopus 로고    scopus 로고
    • The membrane anchor of microsomal epoxide hydrolase from human, rat, and rabbit displays an unexpected membrane topology
    • 10.1006/bbrc.1997.7044
    • R Holler M Arand A Mecky F Oesch T Friedberg 1997 The membrane anchor of microsomal epoxide hydrolase from human, rat, and rabbit displays an unexpected membrane topology Biochem Biophys Res Commun 236 754 759 10.1006/bbrc.1997.7044
    • (1997) Biochem Biophys Res Commun , vol.236 , pp. 754-759
    • Holler, R.1    Arand, M.2    Mecky, A.3    Oesch, F.4    Friedberg, T.5
  • 83
    • 0034285515 scopus 로고    scopus 로고
    • Alpha/beta-hydrolase fold enzymes: Structures, functions and mechanisms
    • 10.2174/1389203003381405
    • M Holmquist 2000 Alpha/beta-hydrolase fold enzymes: structures, functions and mechanisms Curr Protein Pept Sci 1 209 235 10.2174/1389203003381405
    • (2000) Curr Protein Pept Sci , vol.1 , pp. 209-235
    • Holmquist, M.1
  • 84
    • 0028786094 scopus 로고
    • Relationship between the microsomal epoxide hydrolase and the hepatocellular transport of bile acids and xenobiotics
    • W Honscha HD Platte F Oesch T Friedberg 1995 Relationship between the microsomal epoxide hydrolase and the hepatocellular transport of bile acids and xenobiotics Biochem J 311 Pt 3 975 979
    • (1995) Biochem J , vol.311 , Issue.PT 3 , pp. 975-979
    • Honscha, W.1    Platte, H.D.2    Oesch, F.3    Friedberg, T.4
  • 85
    • 0027389456 scopus 로고
    • Activation of K+ channel in vascular smooth muscles by cytochrome P450 metabolites of arachidonic acid
    • 10.1016/0014-2999(93)90805-R
    • S Hu HS Kim 1993 Activation of K+ channel in vascular smooth muscles by cytochrome P450 metabolites of arachidonic acid Eur J Pharmacol 230 215 221 10.1016/0014-2999(93)90805-R
    • (1993) Eur J Pharmacol , vol.230 , pp. 215-221
    • Hu, S.1    Kim, H.S.2
  • 86
    • 23944460748 scopus 로고    scopus 로고
    • Epoxide hydrolase and epoxygenase metabolites as therapeutic targets for renal diseases
    • 10.1152/ajprenal.00350.2004
    • JD Imig 2005 Epoxide hydrolase and epoxygenase metabolites as therapeutic targets for renal diseases Am J Physiol Renal Physiol 289 F496 F503 10.1152/ajprenal.00350.2004
    • (2005) Am J Physiol Renal Physiol , vol.289
    • Imig, J.D.1
  • 88
    • 0036179501 scopus 로고    scopus 로고
    • Soluble epoxide hydrolase inhibition lowers arterial blood pressure in angiotensin II hypertension
    • 10.1161/hy0202.103788
    • JD Imig X Zhao JH Capdevila C Morisseau BD Hammock 2002 Soluble epoxide hydrolase inhibition lowers arterial blood pressure in angiotensin II hypertension Hypertension 39 690 694 10.1161/hy0202.103788
    • (2002) Hypertension , vol.39 , pp. 690-694
    • Imig, J.D.1    Zhao, X.2    Capdevila, J.H.3    Morisseau, C.4    Hammock, B.D.5
  • 89
    • 33750529521 scopus 로고    scopus 로고
    • Inhibition of soluble epoxide hydrolase reduces LPS-induced thermal hyperalgesia and mechanical allodynia in a rat model of inflammatory pain
    • 10.1016/j.lfs.2006.07.031
    • B Inceoglu SL Jinks KR Schmelzer T Waite IH Kim BD Hammock 2006 Inhibition of soluble epoxide hydrolase reduces LPS-induced thermal hyperalgesia and mechanical allodynia in a rat model of inflammatory pain Life Sci 79 2311 2319 10.1016/j.lfs.2006.07.031
    • (2006) Life Sci , vol.79 , pp. 2311-2319
    • Inceoglu, B.1    Jinks, S.L.2    Schmelzer, K.R.3    Waite, T.4    Kim, I.H.5    Hammock, B.D.6
  • 90
    • 0024358064 scopus 로고
    • Cloning of 1, 2-dichloroethane degradation genes of Xanthobacter autotrophicus GJ10 and expression and sequencing of the dhlA gene
    • DB Janssen F Pries J van der Ploeg B Kazemier P Terpstra B Witholt 1989 Cloning of 1, 2-dichloroethane degradation genes of Xanthobacter autotrophicus GJ10 and expression and sequencing of the dhlA gene J Bacteriol 171 6791 6799
    • (1989) J Bacteriol , vol.171 , pp. 6791-6799
    • Janssen, D.B.1    Pries, F.2    Van Der Ploeg, J.3    Kazemier, B.4    Terpstra, P.5    Witholt, B.6
  • 91
    • 0028889581 scopus 로고
    • Tissue specific basal expression of soluble murine epoxide hydrolase and effects of clofibrate on the mRNA levels in extrahepatic tissues and liver
    • 10.1007/s002040050250
    • C Johansson A Stark M Sandberg B Ek L Rask J Meijer 1995 Tissue specific basal expression of soluble murine epoxide hydrolase and effects of clofibrate on the mRNA levels in extrahepatic tissues and liver Arch Toxicol 70 61 63 10.1007/s002040050250
    • (1995) Arch Toxicol , vol.70 , pp. 61-63
    • Johansson, C.1    Stark, A.2    Sandberg, M.3    Ek, B.4    Rask, L.5    Meijer, J.6
  • 92
    • 23644459507 scopus 로고    scopus 로고
    • Structure of an atypical epoxide hydrolase from Mycobacterium tuberculosis gives insights into its function
    • 10.1016/j.jmb.2005.06.055
    • P Johansson T Unge A Cronin M Arand T Bergfors TA Jones SL Mowbray 2005 Structure of an atypical epoxide hydrolase from Mycobacterium tuberculosis gives insights into its function J Mol Biol 351 1048 1056 10.1016/j.jmb.2005.06.055
    • (2005) J Mol Biol , vol.351 , pp. 1048-1056
    • Johansson, P.1    Unge, T.2    Cronin, A.3    Arand, M.4    Bergfors, T.5    Jones, T.A.6    Mowbray, S.L.7
  • 94
    • 0036147887 scopus 로고    scopus 로고
    • Expression of human microsomal epoxide hydrolase in Saccharomyces cerevisiae reveals a functional role in aflatoxin B1 detoxification
    • 10.1093/toxsci/65.1.35
    • EJ Kelly KE Erickson C Sengstag DL Eaton 2002 Expression of human microsomal epoxide hydrolase in Saccharomyces cerevisiae reveals a functional role in aflatoxin B1 detoxification Toxicol Sci 65 35 42 10.1093/toxsci/65.1.35
    • (2002) Toxicol Sci , vol.65 , pp. 35-42
    • Kelly, E.J.1    Erickson, K.E.2    Sengstag, C.3    Eaton, D.L.4
  • 95
    • 1842555060 scopus 로고    scopus 로고
    • Design, synthesis, and biological activity of 1, 3-disubstituted ureas as potent inhibitors of the soluble epoxide hydrolase of increased water solubility
    • 10.1021/jm030514j
    • IH Kim C Morisseau T Watanabe BD Hammock 2004 Design, synthesis, and biological activity of 1, 3-disubstituted ureas as potent inhibitors of the soluble epoxide hydrolase of increased water solubility J Med Chem 47 2110 2122 10.1021/jm030514j
    • (2004) J Med Chem , vol.47 , pp. 2110-2122
    • Kim, I.H.1    Morisseau, C.2    Watanabe, T.3    Hammock, B.D.4
  • 96
    • 33750949953 scopus 로고    scopus 로고
    • Design of bioavailable derivatives of 12-(3-adamantan-1-yl-ureido) dodecanoic acid, a potent inhibitor of the soluble epoxide hydrolase
    • 10.1016/j.bmc.2006.09.057
    • IH Kim K Nishi HJ Tsai T Bradford Y Koda T Watanabe C Morisseau J Blanchfield I Toth BD Hammock 2007 Design of bioavailable derivatives of 12-(3-adamantan-1-yl-ureido)dodecanoic acid, a potent inhibitor of the soluble epoxide hydrolase Bioorg Med Chem 15 312 323 10.1016/j.bmc.2006.09.057
    • (2007) Bioorg Med Chem , vol.15 , pp. 312-323
    • Kim, I.H.1    Nishi, K.2    Tsai, H.J.3    Bradford, T.4    Koda, Y.5    Watanabe, T.6    Morisseau, C.7    Blanchfield, J.8    Toth, I.9    Hammock, B.D.10
  • 97
    • 33644874090 scopus 로고    scopus 로고
    • EPHX1 polymorphisms and the risk of lung cancer: A HuGE review
    • 10.1097/01.ede.0000187627.70026.23
    • C Kiyohara K Yoshimasu K Takayama Y Nakanishi 2006 EPHX1 polymorphisms and the risk of lung cancer: a HuGE review Epidemiology 17 89 99 10.1097/01.ede.0000187627.70026.23
    • (2006) Epidemiology , vol.17 , pp. 89-99
    • Kiyohara, C.1    Yoshimasu, K.2    Takayama, K.3    Nakanishi, Y.4
  • 98
    • 0027182044 scopus 로고
    • Isolation and characterization of a cDNA encoding rat liver cytosolic epoxide hydrolase and its functional expression in Escherichia coli
    • M Knehr H Thomas M Arand T Gebel HD Zeller F Oesch 1993 Isolation and characterization of a cDNA encoding rat liver cytosolic epoxide hydrolase and its functional expression in Escherichia coli J Biol Chem 268 17623 17627
    • (1993) J Biol Chem , vol.268 , pp. 17623-17627
    • Knehr, M.1    Thomas, H.2    Arand, M.3    Gebel, T.4    Zeller, H.D.5    Oesch, F.6
  • 100
    • 34247525219 scopus 로고    scopus 로고
    • Polymorphisms in the human soluble epoxide hydrolase gene EPHX2 linked to neuronal survival after ischemic injury
    • 10.1523/JNEUROSCI.0056-07.2007
    • IP Koerner R Jacks AE DeBarber D Koop P Mao DF Grant NJ Alkayed 2007 Polymorphisms in the human soluble epoxide hydrolase gene EPHX2 linked to neuronal survival after ischemic injury J Neurosci 27 4642 4649 10.1523/JNEUROSCI.0056-07.2007
    • (2007) J Neurosci , vol.27 , pp. 4642-4649
    • Koerner, I.P.1    Jacks, R.2    Debarber, A.E.3    Koop, D.4    Mao, P.5    Grant, D.F.6    Alkayed, N.J.7
  • 101
    • 0028116826 scopus 로고
    • Computer analysis of bacterial haloacid dehalogenases defines a large superfamily of hydrolases with diverse specificity
    • 10.1006/jmbi.1994.1711
    • EV Koonin RL Tatusov 1994 Computer analysis of bacterial haloacid dehalogenases defines a large superfamily of hydrolases with diverse specificity Application of an iterative approach to database search. J Mol Biol 244 125 132 10.1006/jmbi.1994.1711
    • (1994) Application of An Iterative Approach to Database Search. J Mol Biol , vol.244 , pp. 125-132
    • Koonin, E.V.1    Tatusov, R.L.2
  • 102
    • 0030745891 scopus 로고    scopus 로고
    • Epoxide hydrolase-dependent metabolism of butadiene monoxide to 3-butene-1, 2-diol in mouse, rat, and human liver
    • RJ Krause JE Sharer AA Elfarra 1997 Epoxide hydrolase-dependent metabolism of butadiene monoxide to 3-butene-1, 2-diol in mouse, rat, and human liver Drug Metab Dispos 25 1013 1015
    • (1997) Drug Metab Dispos , vol.25 , pp. 1013-1015
    • Krause, R.J.1    Sharer, J.E.2    Elfarra, A.A.3
  • 103
    • 0035260034 scopus 로고    scopus 로고
    • Role of transcription factor Nrf2 in the induction of hepatic phase 2 and antioxidative enzymes in vivo by the cancer chemoprotective agent, 3H-1, 2-dimethiole-3-thione
    • MK Kwak K Itoh M Yamamoto TR Sutter TW Kensler 2001 Role of transcription factor Nrf2 in the induction of hepatic phase 2 and antioxidative enzymes in vivo by the cancer chemoprotective agent, 3H-1, 2-dimethiole-3-thione Mol Med 7 135 145
    • (2001) Mol Med , vol.7 , pp. 135-145
    • Kwak, M.K.1    Itoh, K.2    Yamamoto, M.3    Sutter, T.R.4    Kensler, T.W.5
  • 104
    • 0028354487 scopus 로고
    • Microsomal and soluble epoxide hydrolases are members of the same family of C-X bond hydrolase enzymes
    • 10.1021/tx00038a001
    • GM Lacourciere RN Armstrong 1994 Microsomal and soluble epoxide hydrolases are members of the same family of C-X bond hydrolase enzymes Chem Res Toxicol 7 121 124 10.1021/tx00038a001
    • (1994) Chem Res Toxicol , vol.7 , pp. 121-124
    • Lacourciere, G.M.1    Armstrong, R.N.2
  • 105
    • 0027456534 scopus 로고
    • Interaction of hepatic microsomal epoxide hydrolase derived from a recombinant baculovirus expression system with an azarene oxide and an aziridine substrate analogue
    • 10.1021/bi00061a019
    • GM Lacourciere VN Vakharia CP Tan DI Morris GH Edwards M Moos RN Armstrong 1993 Interaction of hepatic microsomal epoxide hydrolase derived from a recombinant baculovirus expression system with an azarene oxide and an aziridine substrate analogue Biochemistry 32 2610 2616 10.1021/bi00061a019
    • (1993) Biochemistry , vol.32 , pp. 2610-2616
    • Lacourciere, G.M.1    Vakharia, V.N.2    Tan, C.P.3    Morris, D.I.4    Edwards, G.H.5    Moos, M.6    Armstrong, R.N.7
  • 106
    • 1542267779 scopus 로고    scopus 로고
    • Analysis of the substrate specificity loop of the HAD superfamily cap domain
    • 10.1021/bi0356810
    • SD Lahiri G Zhang J Dai D Dunaway-Mariano KN Allen 2004 Analysis of the substrate specificity loop of the HAD superfamily cap domain Biochemistry 43 2812 2820 10.1021/bi0356810
    • (2004) Biochemistry , vol.43 , pp. 2812-2820
    • Lahiri, S.D.1    Zhang, G.2    Dai, J.3    Dunaway-Mariano, D.4    Allen, K.N.5
  • 107
    • 33750689867 scopus 로고    scopus 로고
    • Diversification of function in the haloacid dehalogenase enzyme superfamily: The role of the cap domain in hydrolytic phosphoruscarbon bond cleavage
    • 10.1016/j.bioorg.2006.09.007
    • SD Lahiri G Zhang D Dunaway-Mariano KN Allen 2006 Diversification of function in the haloacid dehalogenase enzyme superfamily: the role of the cap domain in hydrolytic phosphoruscarbon bond cleavage Bioorg Chem 34 394 409 10.1016/j.bioorg.2006.09.007
    • (2006) Bioorg Chem , vol.34 , pp. 394-409
    • Lahiri, S.D.1    Zhang, G.2    Dunaway-Mariano, D.3    Allen, K.N.4
  • 108
    • 0025767695 scopus 로고
    • Hepoxilin A3 (HxA3) is formed by the rat aorta and is metabolized into HxA3-C, a glutathione conjugate
    • O Laneuville EJ Corey R Couture CR Pace-Asciak 1991 Hepoxilin A3 (HxA3) is formed by the rat aorta and is metabolized into HxA3-C, a glutathione conjugate Biochim Biophys Acta 1084 60 68
    • (1991) Biochim Biophys Acta , vol.1084 , pp. 60-68
    • Laneuville, O.1    Corey, E.J.2    Couture, R.3    Pace-Asciak, C.R.4
  • 109
    • 0032478337 scopus 로고    scopus 로고
    • Mechanism of microsomal epoxide hydrolase. Semifunctional site-specific mutants affecting the alkylation half-reaction
    • 10.1021/bi972737f
    • LT Laughlin HF Tzeng S Lin RN Armstrong 1998 Mechanism of microsomal epoxide hydrolase. Semifunctional site-specific mutants affecting the alkylation half-reaction Biochemistry 37 2897 2904 10.1021/bi972737f
    • (1998) Biochemistry , vol.37 , pp. 2897-2904
    • Laughlin, L.T.1    Tzeng, H.F.2    Lin, S.3    Armstrong, R.N.4
  • 111
    • 33745222033 scopus 로고    scopus 로고
    • Genetic variation in soluble epoxide hydrolase (EPHX2) and risk of coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) study
    • 10.1093/hmg/ddl085
    • CR Lee KE North MS Bray M Fornage JM Seubert JW Newman BD Hammock DJ Couper G Heiss DC Zeldin 2006 Genetic variation in soluble epoxide hydrolase (EPHX2) and risk of coronary heart disease: The Atherosclerosis Risk in Communities (ARIC) study Hum Mol Genet 15 1640 1649 10.1093/hmg/ddl085
    • (2006) Hum Mol Genet , vol.15 , pp. 1640-1649
    • Lee, C.R.1    North, K.E.2    Bray, M.S.3    Fornage, M.4    Seubert, J.M.5    Newman, J.W.6    Hammock, B.D.7    Couper, D.J.8    Heiss, G.9    Zeldin, D.C.10
  • 112
    • 0030782032 scopus 로고    scopus 로고
    • Genomic structure and parent-of-origin-specific methylation of Peg1
    • 10.1093/hmg/6.11.1907
    • L Lefebvre S Viville SC Barton F Ishino MA Surani 1997 Genomic structure and parent-of-origin-specific methylation of Peg1 Hum Mol Genet 6 1907 1915 10.1093/hmg/6.11.1907
    • (1997) Hum Mol Genet , vol.6 , pp. 1907-1915
    • Lefebvre, L.1    Viville, S.2    Barton, S.C.3    Ishino, F.4    Surani, M.A.5
  • 113
    • 0030973315 scopus 로고    scopus 로고
    • Epoxyeicosatrienoic acids activate K+ channels in coronary smooth muscle through a guanine nucleotide binding protein
    • PL Li WB Campbell 1997 Epoxyeicosatrienoic acids activate K+ channels in coronary smooth muscle through a guanine nucleotide binding protein Circ Res 80 877 884
    • (1997) Circ Res , vol.80 , pp. 877-884
    • Li, P.L.1    Campbell, W.B.2
  • 114
    • 42649126674 scopus 로고    scopus 로고
    • Soluble epoxide hydrolase inhibitor, AUDA, prevents early salt-sensitive hypertension
    • 10.2741/2942
    • J Li MA Carroll PN Chander JR Falck B Sangras CT Stier 2008 Soluble epoxide hydrolase inhibitor, AUDA, prevents early salt-sensitive hypertension Front Biosci 13 3480 3487 10.2741/2942
    • (2008) Front Biosci , vol.13 , pp. 3480-3487
    • Li, J.1    Carroll, M.A.2    Chander, P.N.3    Falck, J.R.4    Sangras, B.5    Stier, C.T.6
  • 115
    • 34247853336 scopus 로고    scopus 로고
    • Genetic polymorphism and gene expression of microsomal epoxide hydrolase in non-small cell lung cancer
    • TS Lin HH Huang YH Fan SH Chiou KC Chow 2007 Genetic polymorphism and gene expression of microsomal epoxide hydrolase in non-small cell lung cancer Oncol Rep 17 565 572
    • (2007) Oncol Rep , vol.17 , pp. 565-572
    • Lin, T.S.1    Huang, H.H.2    Fan, Y.H.3    Chiou, S.H.4    Chow, K.C.5
  • 117
    • 33645999663 scopus 로고    scopus 로고
    • Expression of microsomal epoxide hydrolase is elevated in Alzheimer's hippocampus and induced by exogenous beta-amyloid and trimethyl-tin
    • 10.1111/j.1460-9568.2006.04724.x
    • M Liu A Sun EJ Shin X Liu SG Kim CR Runyons W Markesbery HC Kim G Bing 2006 Expression of microsomal epoxide hydrolase is elevated in Alzheimer's hippocampus and induced by exogenous beta-amyloid and trimethyl-tin Eur J Neurosci 23 2027 2034 10.1111/j.1460-9568.2006.04724.x
    • (2006) Eur J Neurosci , vol.23 , pp. 2027-2034
    • Liu, M.1    Sun, A.2    Shin, E.J.3    Liu, X.4    Kim, S.G.5    Runyons, C.R.6    Markesbery, W.7    Kim, H.C.8    Bing, G.9
  • 118
    • 57049090465 scopus 로고    scopus 로고
    • Microsomal epoxide hydrolase deletion enhances tyrosine hydroxylase phosphorylation in mice after MPTP treatment
    • Liu M, Hunter R, Nguyen XV, Kim HC, Bing G (2008) Microsomal epoxide hydrolase deletion enhances tyrosine hydroxylase phosphorylation in mice after MPTP treatment. J Neurosci Res 86:2792-2801
    • (2008) J Neurosci Res , vol.86 , pp. 2792-2801
    • Liu, M.1    Hunter, R.2    Nguyen, X.V.3    Kim, H.C.4    Bing, G.5
  • 119
    • 0023103205 scopus 로고
    • Induction of cytosolic and microsomal epoxide hydrolases and proliferation of peroxisomes and mitochondria in mouse liver after dietary exposure to p-chlorophenoxyacetic acid, 2, 4-dichlorophenoxyacetic acid and 2, 4, 5-trichlorophenoxyacetic acid
    • 10.1016/0006-2952(87)90169-9
    • B Lundgren J Meijer JW DePierre 1987 Induction of cytosolic and microsomal epoxide hydrolases and proliferation of peroxisomes and mitochondria in mouse liver after dietary exposure to p-chlorophenoxyacetic acid, 2, 4-dichlorophenoxyacetic acid and 2, 4, 5-trichlorophenoxyacetic acid Biochem Pharmacol 36 815 821 10.1016/0006-2952(87)90169-9
    • (1987) Biochem Pharmacol , vol.36 , pp. 815-821
    • Lundgren, B.1    Meijer, J.2    Depierre, J.W.3
  • 120
    • 44649141830 scopus 로고    scopus 로고
    • Protein quaternary structure and expression levels contribute to peroxisomal-targeting-sequence-1-mediated peroxisomal import of human soluble epoxide hydrolase
    • 10.1016/j.jmb.2008.04.064
    • B Luo C Norris ES Bolstad DA Knecht DF Grant 2008 Protein quaternary structure and expression levels contribute to peroxisomal-targeting-sequence-1- mediated peroxisomal import of human soluble epoxide hydrolase J Mol Biol 380 31 41 10.1016/j.jmb.2008.04.064
    • (2008) J Mol Biol , vol.380 , pp. 31-41
    • Luo, B.1    Norris, C.2    Bolstad, E.S.3    Knecht, D.A.4    Grant, D.F.5
  • 125
    • 43249088347 scopus 로고    scopus 로고
    • Induction of drug metabolism enzymes and transporters by oltipraz in rats
    • 10.1002/jbt.20225
    • MD Merrell LM Augustine AL Slitt NJ Cherrington 2008 Induction of drug metabolism enzymes and transporters by oltipraz in rats J Biochem Mol Toxicol 22 128 135 10.1002/jbt.20225
    • (2008) J Biochem Mol Toxicol , vol.22 , pp. 128-135
    • Merrell, M.D.1    Augustine, L.M.2    Slitt, A.L.3    Cherrington, N.J.4
  • 126
    • 30544449595 scopus 로고    scopus 로고
    • Cytochrome P450 epoxygenases 2C8 and 2C9 are implicated in hypoxia-induced endothelial cell migration and angiogenesis
    • 10.1242/jcs.02674
    • UR Michaelis B Fisslthaler E Barbosa-Sicard JR Falck I Fleming R Busse 2005 Cytochrome P450 epoxygenases 2C8 and 2C9 are implicated in hypoxia-induced endothelial cell migration and angiogenesis J Cell Sci 118 5489 5498 10.1242/jcs.02674
    • (2005) J Cell Sci , vol.118 , pp. 5489-5498
    • Michaelis, U.R.1    Fisslthaler, B.2    Barbosa-Sicard, E.3    Falck, J.R.4    Fleming, I.5    Busse, R.6
  • 128
    • 36248970167 scopus 로고    scopus 로고
    • Cytochrome P4501A1 and microsomal epoxide hydrolase gene polymorphisms: Gene-environment interaction and risk of prostate cancer
    • 10.1089/dna.2007.0630
    • RD Mittal DL Srivastava 2007 Cytochrome P4501A1 and microsomal epoxide hydrolase gene polymorphisms: gene-environment interaction and risk of prostate cancer DNA Cell Biol 26 791 798 10.1089/dna.2007.0630
    • (2007) DNA Cell Biol , vol.26 , pp. 791-798
    • Mittal, R.D.1    Srivastava, D.L.2
  • 129
    • 0033588227 scopus 로고    scopus 로고
    • Targeted disruption of the microsomal epoxide hydrolase gene. Microsomal epoxide hydrolase is required for the carcinogenic activity of 7, 12-dimethylbenz[a]anthracene
    • 10.1074/jbc.274.34.23963
    • M Miyata G Kudo YH Lee TJ Yang HV Gelboin P Fernandez-Salguero S Kimura FJ Gonzalez 1999 Targeted disruption of the microsomal epoxide hydrolase gene. Microsomal epoxide hydrolase is required for the carcinogenic activity of 7, 12-dimethylbenz[a]anthracene J Biol Chem 274 23963 23968 10.1074/jbc.274.34. 23963
    • (1999) J Biol Chem , vol.274 , pp. 23963-23968
    • Miyata, M.1    Kudo, G.2    Lee, Y.H.3    Yang, T.J.4    Gelboin, H.V.5    Fernandez-Salguero, P.6    Kimura, S.7    Gonzalez, F.J.8
  • 132
    • 0034730072 scopus 로고    scopus 로고
    • The crystal structure of bacillus cereus phosphonoacetaldehyde hydrolase: Insight into catalysis of phosphorus bond cleavage and catalytic diversification within the HAD enzyme superfamily
    • 10.1021/bi001171j
    • MC Morais W Zhang AS Baker G Zhang D Dunaway-Mariano KN Allen 2000 The crystal structure of bacillus cereus phosphonoacetaldehyde hydrolase: insight into catalysis of phosphorus bond cleavage and catalytic diversification within the HAD enzyme superfamily Biochemistry 39 10385 10396 10.1021/bi001171j
    • (2000) Biochemistry , vol.39 , pp. 10385-10396
    • Morais, M.C.1    Zhang, W.2    Baker, A.S.3    Zhang, G.4    Dunaway-Mariano, D.5    Allen, K.N.6
  • 133
    • 13844316739 scopus 로고    scopus 로고
    • Epoxide hydrolases: Mechanisms, inhibitor designs, and biological roles
    • 10.1146/annurev.pharmtox.45.120403.095920
    • C Morisseau BD Hammock 2005 Epoxide hydrolases: mechanisms, inhibitor designs, and biological roles Annu Rev Pharmacol Toxicol 45 311 333 10.1146/annurev.pharmtox.45.120403.095920
    • (2005) Annu Rev Pharmacol Toxicol , vol.45 , pp. 311-333
    • Morisseau, C.1    Hammock, B.D.2
  • 134
    • 0032529615 scopus 로고    scopus 로고
    • Mechanism of mammalian soluble epoxide hydrolase inhibition by chalcone oxide derivatives
    • 10.1006/abbi.1998.0756
    • C Morisseau G Du JW Newman BD Hammock 1998 Mechanism of mammalian soluble epoxide hydrolase inhibition by chalcone oxide derivatives Arch Biochem Biophys 356 214 228 10.1006/abbi.1998.0756
    • (1998) Arch Biochem Biophys , vol.356 , pp. 214-228
    • Morisseau, C.1    Du, G.2    Newman, J.W.3    Hammock, B.D.4
  • 135
    • 0035061917 scopus 로고    scopus 로고
    • Inhibition of microsomal epoxide hydrolases by ureas, amides, and amines
    • 10.1021/tx0001732
    • C Morisseau JW Newman DL Dowdy MH Goodrow BD Hammock 2001 Inhibition of microsomal epoxide hydrolases by ureas, amides, and amines Chem Res Toxicol 14 409 415 10.1021/tx0001732
    • (2001) Chem Res Toxicol , vol.14 , pp. 409-415
    • Morisseau, C.1    Newman, J.W.2    Dowdy, D.L.3    Goodrow, M.H.4    Hammock, B.D.5
  • 139
    • 33745712762 scopus 로고    scopus 로고
    • X-ray structure of potato epoxide hydrolase sheds light on substrate specificity in plant enzymes
    • 10.1110/ps.051792106
    • SL Mowbray LT Elfstrom KM Ahlgren CE Andersson M Widersten 2006 X-ray structure of potato epoxide hydrolase sheds light on substrate specificity in plant enzymes Protein Sci 15 1628 1637 10.1110/ps.051792106
    • (2006) Protein Sci , vol.15 , pp. 1628-1637
    • Mowbray, S.L.1    Elfstrom, L.T.2    Ahlgren, K.M.3    Andersson, C.E.4    Widersten, M.5
  • 140
    • 2442572098 scopus 로고    scopus 로고
    • Identification of hepoxilin A3 in inflammatory events: A required role in neutrophil migration across intestinal epithelia
    • 10.1073/pnas.0400832101
    • RJ Mrsny AT Gewirtz D Siccardi T Savidge BP Hurley JL Madara BA [tmp] McCormick 2004 Identification of hepoxilin A3 in inflammatory events: a required role in neutrophil migration across intestinal epithelia Proc Natl Acad Sci USA 101 7421 7426 10.1073/pnas.0400832101
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 7421-7426
    • Mrsny, R.J.1    Gewirtz, A.T.2    Siccardi, D.3    Savidge, T.4    Hurley, B.P.5    Madara, J.L.6    McCormick, B.A.7
  • 141
    • 0032979423 scopus 로고    scopus 로고
    • Differential subcellular localization of endogenous and transfected soluble epoxide hydrolase in mammalian cells: Evidence for isozyme variants
    • 10.1016/S0014-5793(99)00142-8
    • RT Mullen RN Trelease H Duerk M Arand BD Hammock F Oesch DF Grant 1999 Differential subcellular localization of endogenous and transfected soluble epoxide hydrolase in mammalian cells: evidence for isozyme variants FEBS Lett 445 301 305 10.1016/S0014-5793(99)00142-8
    • (1999) FEBS Lett , vol.445 , pp. 301-305
    • Mullen, R.T.1    Trelease, R.N.2    Duerk, H.3    Arand, M.4    Hammock, B.D.5    Oesch, F.6    Grant, D.F.7
  • 142
    • 0040346688 scopus 로고    scopus 로고
    • Visualization of a covalent intermediate between microsomal epoxide hydrolase, but not cholesterol epoxide hydrolase, and their substrates
    • 10.1111/j.1432-1033.1997.00490.x
    • F Muller M Arand H Frank A Seidel W Hinz L Winkler K Hanel E Blee JK Beetham BD Hammock F Oesch 1997 Visualization of a covalent intermediate between microsomal epoxide hydrolase, but not cholesterol epoxide hydrolase, and their substrates Eur J Biochem 245 490 496 10.1111/j.1432-1033.1997.00490.x
    • (1997) Eur J Biochem , vol.245 , pp. 490-496
    • Muller, F.1    Arand, M.2    Frank, H.3    Seidel, A.4    Hinz, W.5    Winkler, L.6    Hanel, K.7    Blee, E.8    Beetham, J.K.9    Hammock, B.D.10    Oesch, F.11
  • 145
    • 0037452577 scopus 로고    scopus 로고
    • The soluble epoxide hydrolase encoded by EPXH2 is a bifunctional enzyme with novel lipid phosphate phosphatase activity
    • 10.1073/pnas.0437724100
    • JW Newman C Morisseau TR Harris BD Hammock 2003 The soluble epoxide hydrolase encoded by EPXH2 is a bifunctional enzyme with novel lipid phosphate phosphatase activity Proc Natl Acad Sci USA 100 1558 1563 10.1073/pnas. 0437724100
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 1558-1563
    • Newman, J.W.1    Morisseau, C.2    Harris, T.R.3    Hammock, B.D.4
  • 146
    • 14644429730 scopus 로고    scopus 로고
    • Epoxide hydrolases: Their roles and interactions with lipid metabolism
    • 10.1016/j.plipres.2004.10.001
    • JW Newman C Morisseau BD Hammock 2005 Epoxide hydrolases: their roles and interactions with lipid metabolism Prog Lipid Res 44 1 51 10.1016/j.plipres. 2004.10.001
    • (2005) Prog Lipid Res , vol.44 , pp. 1-51
    • Newman, J.W.1    Morisseau, C.2    Hammock, B.D.3
  • 147
    • 34447316152 scopus 로고    scopus 로고
    • Structure, biochemistry and biology of hepoxilins: An update
    • 10.1111/j.1742-4658.2007.05910.x
    • S Nigam MP Zafiriou R Deva R Ciccoli R Roux-Van der Merwe 2007 Structure, biochemistry and biology of hepoxilins: an update FEBS J 274 3503 3512 10.1111/j.1742-4658.2007.05910.x
    • (2007) FEBS J , vol.274 , pp. 3503-3512
    • Nigam, S.1    Zafiriou, M.P.2    Deva, R.3    Ciccoli, R.4    Roux-Van Der Merwe, R.5
  • 148
    • 55549118918 scopus 로고    scopus 로고
    • Mesoderm-specific transcript is associated with fat mass expansion in response to a positive energy balance
    • 10.1096/fj.08-108266
    • L Nikonova RA Koza T Mendoza PM Chao JP Curley LP Kozak 2008 Mesoderm-specific transcript is associated with fat mass expansion in response to a positive energy balance FASEB J 22 3925 3937 10.1096/fj.08-108266
    • (2008) FASEB J , vol.22 , pp. 3925-3937
    • Nikonova, L.1    Koza, R.A.2    Mendoza, T.3    Chao, P.M.4    Curley, J.P.5    Kozak, L.P.6
  • 149
    • 0015849224 scopus 로고
    • Mammalian epoxide hydrolases: Inducible enzymes catalysing the inactivation of carcinogenic and cytotoxic metabolites derived from aromatic and olefinic compounds
    • F Oesch 1973 Mammalian epoxide hydrolases: inducible enzymes catalysing the inactivation of carcinogenic and cytotoxic metabolites derived from aromatic and olefinic compounds Xenobiotica 3 305 340
    • (1973) Xenobiotica , vol.3 , pp. 305-340
    • Oesch, F.1
  • 150
    • 0015956853 scopus 로고
    • Purification and specificity of a human microsomal epoxide hydratase
    • F Oesch 1974 Purification and specificity of a human microsomal epoxide hydratase Biochem J 139 77 88
    • (1974) Biochem J , vol.139 , pp. 77-88
    • Oesch, F.1
  • 151
    • 0021341632 scopus 로고
    • Existence of multiple forms of microsomal epoxide hydrolases with radically different substrate specificities
    • 10.1093/carcin/5.1.7
    • F Oesch CW Timms CH Walker TM Guenthner A Sparrow T Watabe CR Wolf 1984 Existence of multiple forms of microsomal epoxide hydrolases with radically different substrate specificities Carcinogenesis 5 7 9 10.1093/carcin/5.1.7
    • (1984) Carcinogenesis , vol.5 , pp. 7-9
    • Oesch, F.1    Timms, C.W.2    Walker, C.H.3    Guenthner, T.M.4    Sparrow, A.5    Watabe, T.6    Wolf, C.R.7
  • 153
    • 0034084246 scopus 로고    scopus 로고
    • Metabolic detoxification: Implications for thresholds
    • 10.1177/019262330002800305
    • F Oesch ME Herrero JG Hengstler M Lohmann M Arand 2000 Metabolic detoxification: implications for thresholds Toxicol Pathol 28 382 387 10.1177/019262330002800305
    • (2000) Toxicol Pathol , vol.28 , pp. 382-387
    • Oesch, F.1    Herrero, M.E.2    Hengstler, J.G.3    Lohmann, M.4    Arand, M.5
  • 154
    • 17444380409 scopus 로고    scopus 로고
    • Association of soluble epoxide hydrolase gene polymorphism with insulin resistance in type 2 diabetic patients
    • 10.1016/j.bbrc.2005.03.171
    • K Ohtoshi H Kaneto K Node Y Nakamura T Shiraiwa M Matsuhisa Y Yamasaki 2005 Association of soluble epoxide hydrolase gene polymorphism with insulin resistance in type 2 diabetic patients Biochem Biophys Res Commun 331 347 350 10.1016/j.bbrc.2005.03.171
    • (2005) Biochem Biophys Res Commun , vol.331 , pp. 347-350
    • Ohtoshi, K.1    Kaneto, H.2    Node, K.3    Nakamura, Y.4    Shiraiwa, T.5    Matsuhisa, M.6    Yamasaki, Y.7
  • 155
    • 0019979537 scopus 로고
    • Oxygenation of arachidonic acid by hepatic monooxygenases. Isolation and metabolism of four epoxide intermediates
    • EH Oliw FP Guengerich JA Oates 1982 Oxygenation of arachidonic acid by hepatic monooxygenases. Isolation and metabolism of four epoxide intermediates J Biol Chem 257 3771 3781
    • (1982) J Biol Chem , vol.257 , pp. 3771-3781
    • Oliw, E.H.1    Guengerich, F.P.2    Oates, J.A.3
  • 156
    • 0034653356 scopus 로고    scopus 로고
    • Epoxide hydrolase-polymorphism and role in toxicology
    • 10.1016/S0378-4274(99)00235-0
    • CJ Omiecinski C Hassett V Hosagrahara 2000 Epoxide hydrolase-polymorphism and role in toxicology Toxicol Lett 112-113 365 370 10.1016/S0378-4274(99) 00235-0
    • (2000) Toxicol Lett , vol.112-113 , pp. 365-370
    • Omiecinski, C.J.1    Hassett, C.2    Hosagrahara, V.3
  • 157
    • 0024411066 scopus 로고
    • Purification of hepoxilin epoxide hydrolase from rat liver
    • CR Pace-Asciak WS Lee 1989 Purification of hepoxilin epoxide hydrolase from rat liver J Biol Chem 264 9310 9313
    • (1989) J Biol Chem , vol.264 , pp. 9310-9313
    • Pace-Asciak, C.R.1    Lee, W.S.2
  • 158
    • 0021721480 scopus 로고
    • Hepoxilin, a new family of insulin secretagogues formed by intact rat pancreatic islets
    • 10.1016/0262-1746(84)90069-6
    • CR Pace-Asciak JM Martin 1984 Hepoxilin, a new family of insulin secretagogues formed by intact rat pancreatic islets Prostaglandins Leukot Med 16 173 180 10.1016/0262-1746(84)90069-6
    • (1984) Prostaglandins Leukot Med , vol.16 , pp. 173-180
    • Pace-Asciak, C.R.1    Martin, J.M.2
  • 160
    • 0028950166 scopus 로고
    • Hepoxilins: A review on their enzymatic formation, metabolism and chemical synthesis
    • 10.1007/BF02538262
    • CR Pace-Asciak D Reynaud PM Demin 1995 Hepoxilins: a review on their enzymatic formation, metabolism and chemical synthesis Lipids 30 107 114 10.1007/BF02538262
    • (1995) Lipids , vol.30 , pp. 107-114
    • Pace-Asciak, C.R.1    Reynaud, D.2    Demin, P.M.3
  • 161
    • 0022387754 scopus 로고
    • Subcellular distribution, catalytic properties and partial purification of epoxide hydrolase in the human adrenal gland
    • 10.1016/S0009-2797(85)80133-2
    • D Papadopoulos J Seidegard A Georgellis J Rydstrom 1985 Subcellular distribution, catalytic properties and partial purification of epoxide hydrolase in the human adrenal gland Chem Biol Interact 55 249 260 10.1016/S0009-2797(85) 80133-2
    • (1985) Chem Biol Interact , vol.55 , pp. 249-260
    • Papadopoulos, D.1    Seidegard, J.2    Georgellis, A.3    Rydstrom, J.4
  • 163
    • 0028944334 scopus 로고
    • Molecular and biochemical evidence for the involvement of the Asp-333-His-523 pair in the catalytic mechanism of soluble epoxide hydrolase
    • 10.1074/jbc.270.14.7968
    • F Pinot DF Grant JK Beetham AG Parker B Borhan S Landt AD Jones BD Hammock 1995 Molecular and biochemical evidence for the involvement of the Asp-333-His-523 pair in the catalytic mechanism of soluble epoxide hydrolase J Biol Chem 270 7968 7974 10.1074/jbc.270.14.7968
    • (1995) J Biol Chem , vol.270 , pp. 7968-7974
    • Pinot, F.1    Grant, D.F.2    Beetham, J.K.3    Parker, A.G.4    Borhan, B.5    Landt, S.6    Jones, A.D.7    Hammock, B.D.8
  • 164
    • 0141928109 scopus 로고    scopus 로고
    • 5, 6-Epoxyeicosatrienoic acid mediates the enhanced renal vasodilation to arachidonic acid in the SHR
    • 10.1161/01.HYP.0000090095.87899.36
    • SI Pomposiello J Quilley MA Carroll JR Falck JC [tmp] McGiff 2003 5, 6-Epoxyeicosatrienoic acid mediates the enhanced renal vasodilation to arachidonic acid in the SHR Hypertension 42 548 554 10.1161/01.HYP.0000090095. 87899.36
    • (2003) Hypertension , vol.42 , pp. 548-554
    • Pomposiello, S.I.1    Quilley, J.2    Carroll, M.A.3    Falck, J.R.4    McGiff, J.C.5
  • 165
    • 0041529844 scopus 로고    scopus 로고
    • 11, 12-Epoxyeicosatrienoic acid-induced inhibition of FOXO factors promotes endothelial proliferation by down-regulating p27Kip1
    • 10.1074/jbc.M305385200
    • M Potente B Fisslthaler R Busse I Fleming 2003 11, 12-Epoxyeicosatrienoic acid-induced inhibition of FOXO factors promotes endothelial proliferation by down-regulating p27Kip1 J Biol Chem 278 29619 29625 10.1074/jbc.M305385200
    • (2003) J Biol Chem , vol.278 , pp. 29619-29625
    • Potente, M.1    Fisslthaler, B.2    Busse, R.3    Fleming, I.4
  • 166
    • 0021970065 scopus 로고
    • Cyclopropyl oxiranes: Reversible inhibitors of cytosolic and microsomal epoxide hydrolases
    • 10.1016/0003-9861(85)90288-7
    • GD Prestwich I Lucarelli SK Park DN Loury DE Moody BD Hammock 1985 Cyclopropyl oxiranes: reversible inhibitors of cytosolic and microsomal epoxide hydrolases Arch Biochem Biophys 237 361 372 10.1016/0003-9861(85)90288-7
    • (1985) Arch Biochem Biophys , vol.237 , pp. 361-372
    • Prestwich, G.D.1    Lucarelli, I.2    Park, S.K.3    Loury, D.N.4    Moody, D.E.5    Hammock, B.D.6
  • 168
    • 0031927837 scopus 로고    scopus 로고
    • Human microsomal epoxide hydrolase: 5′-flanking region genetic polymorphisms
    • 10.1093/carcin/19.3.387
    • S Raaka C Hassett CJ Omiencinski 1998 Human microsomal epoxide hydrolase: 5′-flanking region genetic polymorphisms Carcinogenesis 19 387 393 10.1093/carcin/19.3.387
    • (1998) Carcinogenesis , vol.19 , pp. 387-393
    • Raaka, S.1    Hassett, C.2    Omiencinski, C.J.3
  • 169
    • 0021770929 scopus 로고
    • Leukotriene A4 hydrolase in human leukocytes. Purification and properties
    • O Radmark T Shimizu H Jornvall B Samuelsson 1984 Leukotriene A4 hydrolase in human leukocytes. Purification and properties J Biol Chem 259 12339 12345
    • (1984) J Biol Chem , vol.259 , pp. 12339-12345
    • Radmark, O.1    Shimizu, T.2    Jornvall, H.3    Samuelsson, B.4
  • 170
    • 0030450204 scopus 로고    scopus 로고
    • An investigation of multiple biomarkers among workers exposed to styrene and styrene-7, 8-oxide
    • SM Rappaport K Yeowell-O'Connell W Bodell JW Yager E Symanski 1996 An investigation of multiple biomarkers among workers exposed to styrene and styrene-7, 8-oxide Cancer Res 56 5410 5416
    • (1996) Cancer Res , vol.56 , pp. 5410-5416
    • Rappaport, S.M.1    Yeowell-O'Connell, K.2    Bodell, W.3    Yager, J.W.4    Symanski, E.5
  • 171
    • 20444403046 scopus 로고    scopus 로고
    • Use of genetically modified mouse models to assess pathways of benzene-induced bone marrow cytotoxicity and genotoxicity
    • 10.1016/j.cbi.2005.03.020
    • L Recio A Bauer B Faiola 2005 Use of genetically modified mouse models to assess pathways of benzene-induced bone marrow cytotoxicity and genotoxicity Chem Biol Interact 153-154 159 164 10.1016/j.cbi.2005.03.020
    • (2005) Chem Biol Interact , vol.153-154 , pp. 159-164
    • Recio, L.1    Bauer, A.2    Faiola, B.3
  • 172
    • 0017413089 scopus 로고
    • Metabolic epidemiology of colon cancer. Fecal bile acids and neutral sterols in colon cancer patients and patients with adenomatous polyps
    • 10.1002/1097-0142(197706)39:6<2533::AID-CNCR2820390634>3.0.CO;2-X
    • BS Reddy EL Wynder 1977 Metabolic epidemiology of colon cancer. Fecal bile acids and neutral sterols in colon cancer patients and patients with adenomatous polyps Cancer 39 2533 2539 10.1002/1097-0142(197706)39:6<2533:: AID-CNCR2820390634>3.0.CO;2-X
    • (1977) Cancer , vol.39 , pp. 2533-2539
    • Reddy, B.S.1    Wynder, E.L.2
  • 173
    • 0033067172 scopus 로고    scopus 로고
    • Hepoxilin signaling in intact human neutrophils: Biphasic elevation of intracellular calcium by unesterified hepoxilin A3
    • 10.1016/S0014-5793(99)00225-2
    • D Reynaud PM Demin M Sutherland S Nigam CR Pace-Asciak 1999 Hepoxilin signaling in intact human neutrophils: biphasic elevation of intracellular calcium by unesterified hepoxilin A3 FEBS Lett 446 236 238 10.1016/S0014- 5793(99)00225-2
    • (1999) FEBS Lett , vol.446 , pp. 236-238
    • Reynaud, D.1    Demin, P.M.2    Sutherland, M.3    Nigam, S.4    Pace-Asciak, C.R.5
  • 174
    • 30144441695 scopus 로고    scopus 로고
    • Fosfomycin resistance proteins: A nexus of glutathione transferases and epoxide hydrolases in a metalloenzyme superfamily
    • 10.1016/S0076-6879(05)01023-2
    • RE Rigsby KL Fillgrove LA Beihoffer RN Armstrong 2005 Fosfomycin resistance proteins: a nexus of glutathione transferases and epoxide hydrolases in a metalloenzyme superfamily Methods Enzymol 401 367 379 10.1016/S0076- 6879(05)01023-2
    • (2005) Methods Enzymol , vol.401 , pp. 367-379
    • Rigsby, R.E.1    Fillgrove, K.L.2    Beihoffer, L.A.3    Armstrong, R.N.4
  • 176
    • 17644424665 scopus 로고    scopus 로고
    • Comparison of the apoptotic processes induced by the oxysterols 7beta-hydroxycholesterol and cholesterol-5beta, 6beta-epoxide
    • 10.1007/s10565-004-5066-7
    • L Ryan YC O'Callaghan NM O'Brien 2004 Comparison of the apoptotic processes induced by the oxysterols 7beta-hydroxycholesterol and cholesterol-5beta, 6beta-epoxide Cell Biol Toxicol 20 313 323 10.1007/s10565-004-5066-7
    • (2004) Cell Biol Toxicol , vol.20 , pp. 313-323
    • Ryan, L.1    O'Callaghan, Y.C.2    O'Brien, N.M.3
  • 177
    • 0034978048 scopus 로고    scopus 로고
    • Seventy genetic variations in human microsomal and soluble epoxide hydrolase genes (EPHX1 and EPHX2) in the Japanese population
    • 10.1007/s100380170067
    • S Saito A Iida A Sekine C Eguchi Y Miura Y Nakamura 2001 Seventy genetic variations in human microsomal and soluble epoxide hydrolase genes (EPHX1 and EPHX2) in the Japanese population J Hum Genet 46 325 329 10.1007/s100380170067
    • (2001) J Hum Genet , vol.46 , pp. 325-329
    • Saito, S.1    Iida, A.2    Sekine, A.3    Eguchi, C.4    Miura, Y.5    Nakamura, Y.6
  • 178
    • 0029984341 scopus 로고    scopus 로고
    • Structural characterization of the human soluble epoxide hydrolase gene (EPHX2)
    • 10.1006/bbrc.1996.0596
    • M Sandberg J Meijer 1996 Structural characterization of the human soluble epoxide hydrolase gene (EPHX2) Biochem Biophys Res Commun 221 333 339 10.1006/bbrc.1996.0596
    • (1996) Biochem Biophys Res Commun , vol.221 , pp. 333-339
    • Sandberg, M.1    Meijer, J.2
  • 179
    • 0034666150 scopus 로고    scopus 로고
    • Identification and functional characterization of human soluble epoxide hydrolase genetic polymorphisms
    • 10.1074/jbc.M001153200
    • M Sandberg C Hassett ET Adman J Meijer CJ Omiecinski 2000 Identification and functional characterization of human soluble epoxide hydrolase genetic polymorphisms J Biol Chem 275 28873 28881 10.1074/jbc.M001153200
    • (2000) J Biol Chem , vol.275 , pp. 28873-28881
    • Sandberg, M.1    Hassett, C.2    Adman, E.T.3    Meijer, J.4    Omiecinski, C.J.5
  • 180
    • 10744225519 scopus 로고    scopus 로고
    • Soluble epoxide hydrolase variant (Glu287Arg) modifies plasma total cholesterol and triglyceride phenotype in familial hypercholesterolemia: Intrafamilial association study in an eight-generation hyperlipidemic kindred
    • 10.1007/s10038-003-0103-6
    • K Sato M Emi Y Ezura Y Fujita D Takada T Ishigami S Umemura Y Xin LL Wu S Larrinaga-Shum SH Stephenson SC Hunt PN Hopkins 2004 Soluble epoxide hydrolase variant (Glu287Arg) modifies plasma total cholesterol and triglyceride phenotype in familial hypercholesterolemia: intrafamilial association study in an eight-generation hyperlipidemic kindred J Hum Genet 49 29 34 10.1007/s10038-003-0103-6
    • (2004) J Hum Genet , vol.49 , pp. 29-34
    • Sato, K.1    Emi, M.2    Ezura, Y.3    Fujita, Y.4    Takada, D.5    Ishigami, T.6    Umemura, S.7    Xin, Y.8    Wu, L.L.9    Larrinaga-Shum, S.10    Stephenson, S.H.11    Hunt, S.C.12    Hopkins, P.N.13
  • 182
    • 33748797975 scopus 로고    scopus 로고
    • Enhancement of antinociception by coadministration of nonsteroidal anti-inflammatory drugs and soluble epoxide hydrolase inhibitors
    • 10.1073/pnas.0605908103
    • KR Schmelzer B Inceoglu L Kubala IH Kim SL Jinks JP Eiserich BD Hammock 2006 Enhancement of antinociception by coadministration of nonsteroidal anti-inflammatory drugs and soluble epoxide hydrolase inhibitors Proc Natl Acad Sci USA 103 13646 13651 10.1073/pnas.0605908103
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 13646-13651
    • Schmelzer, K.R.1    Inceoglu, B.2    Kubala, L.3    Kim, I.H.4    Jinks, S.L.5    Eiserich, J.P.6    Hammock, B.D.7
  • 183
    • 0035940484 scopus 로고    scopus 로고
    • MDP-1 is a new and distinct member of the haloacid dehalogenase family of aspartate-dependent phosphohydrolases
    • 10.1021/bi011405e
    • JD Selengut 2001 MDP-1 is a new and distinct member of the haloacid dehalogenase family of aspartate-dependent phosphohydrolases Biochemistry 40 12704 12711 10.1021/bi011405e
    • (2001) Biochemistry , vol.40 , pp. 12704-12711
    • Selengut, J.D.1
  • 184
    • 0001586665 scopus 로고
    • Cholesterol epoxide is a direct-acting mutagen
    • 10.1073/pnas.81.13.4198
    • A Sevanian AR Peterson 1984 Cholesterol epoxide is a direct-acting mutagen Proc Natl Acad Sci USA 81 4198 4202 10.1073/pnas.81.13.4198
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 4198-4202
    • Sevanian, A.1    Peterson, A.R.2
  • 185
    • 0023025961 scopus 로고
    • The cytotoxic and mutagenic properties of cholesterol oxidation products
    • 10.1016/0278-6915(86)90295-4
    • A Sevanian AR Peterson 1986 The cytotoxic and mutagenic properties of cholesterol oxidation products Food Chem Toxicol 24 1103 1110 10.1016/0278-6915(86)90295-4
    • (1986) Food Chem Toxicol , vol.24 , pp. 1103-1110
    • Sevanian, A.1    Peterson, A.R.2
  • 186
    • 34047243800 scopus 로고    scopus 로고
    • Xenobiotic-metabolizing enzymes involved in activation and detoxification of carcinogenic polycyclic aromatic hydrocarbons
    • 10.2133/dmpk.21.257
    • T Shimada 2006 Xenobiotic-metabolizing enzymes involved in activation and detoxification of carcinogenic polycyclic aromatic hydrocarbons Drug Metab Pharmacokinet 21 257 276 10.2133/dmpk.21.257
    • (2006) Drug Metab Pharmacokinet , vol.21 , pp. 257-276
    • Shimada, T.1
  • 187
    • 34948860153 scopus 로고    scopus 로고
    • A novel ovary-specific and ovulation-associated variant of epoxide hydrolase 2
    • 10.1016/j.febslet.2007.09.016
    • K Shkolnik S Ben-Dor D Galiani A Hourvitz N Dekel 2007 A novel ovary-specific and ovulation-associated variant of epoxide hydrolase 2 FEBS Lett 581 4891 4898 10.1016/j.febslet.2007.09.016
    • (2007) FEBS Lett , vol.581 , pp. 4891-4898
    • Shkolnik, K.1    Ben-Dor, S.2    Galiani, D.3    Hourvitz, A.4    Dekel, N.5
  • 188
    • 0029758268 scopus 로고    scopus 로고
    • Stereoselective epoxidation and hydration at the K-region of polycyclic aromatic hydrocarbons by cDNA-expressed cytochromes P450 1A1, 1A2, and epoxide hydrolase
    • 10.1021/bi962042z
    • M Shou FJ Gonzalez HV Gelboin 1996 Stereoselective epoxidation and hydration at the K-region of polycyclic aromatic hydrocarbons by cDNA-expressed cytochromes P450 1A1, 1A2, and epoxide hydrolase Biochemistry 35 15807 15813 10.1021/bi962042z
    • (1996) Biochemistry , vol.35 , pp. 15807-15813
    • Shou, M.1    Gonzalez, F.J.2    Gelboin, H.V.3
  • 189
    • 0034704156 scopus 로고    scopus 로고
    • Targeted disruption of soluble epoxide hydrolase reveals a role in blood pressure regulation
    • 10.1074/jbc.M008106200
    • CJ Sinal M Miyata M Tohkin K Nagata JR Bend FJ Gonzalez 2000 Targeted disruption of soluble epoxide hydrolase reveals a role in blood pressure regulation J Biol Chem 275 40504 40510 10.1074/jbc.M008106200
    • (2000) J Biol Chem , vol.275 , pp. 40504-40510
    • Sinal, C.J.1    Miyata, M.2    Tohkin, M.3    Nagata, K.4    Bend, J.R.5    Gonzalez, F.J.6
  • 190
    • 1242270555 scopus 로고    scopus 로고
    • Fungal epoxide hydrolases: New landmarks in sequence-activity space
    • 10.1016/j.tibtech.2004.01.012
    • MS Smit 2004 Fungal epoxide hydrolases: new landmarks in sequence-activity space Trends Biotechnol 22 123 129 10.1016/j.tibtech.2004.01. 012
    • (2004) Trends Biotechnol , vol.22 , pp. 123-129
    • Smit, M.S.1
  • 191
    • 0030849415 scopus 로고    scopus 로고
    • Association between polymorphism in gene for microsomal epoxide hydrolase and susceptibility to emphysema
    • 10.1016/S0140-6736(96)08061-0
    • CA Smith DJ Harrison 1997 Association between polymorphism in gene for microsomal epoxide hydrolase and susceptibility to emphysema Lancet 350 630 633 10.1016/S0140-6736(96)08061-0
    • (1997) Lancet , vol.350 , pp. 630-633
    • Smith, C.A.1    Harrison, D.J.2
  • 192
    • 13844315294 scopus 로고    scopus 로고
    • Attenuation of tobacco smoke-induced lung inflammation by treatment with a soluble epoxide hydrolase inhibitor
    • 10.1073/pnas.0409591102
    • KR Smith KE Pinkerton T Watanabe TL Pedersen SJ Ma BD Hammock 2005 Attenuation of tobacco smoke-induced lung inflammation by treatment with a soluble epoxide hydrolase inhibitor Proc Natl Acad Sci USA 102 2186 2191 10.1073/pnas.0409591102
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 2186-2191
    • Smith, K.R.1    Pinkerton, K.E.2    Watanabe, T.3    Pedersen, T.L.4    Ma, S.J.5    Hammock, B.D.6
  • 193
    • 34247281597 scopus 로고    scopus 로고
    • Anandamide metabolism by human liver and kidney microsomal cytochrome p450 enzymes to form hydroxyeicosatetraenoic and epoxyeicosatrienoic acid ethanolamides
    • 10.1124/jpet.107.119321
    • NT Snider AM Kornilov UM Kent PF Hollenberg 2007 Anandamide metabolism by human liver and kidney microsomal cytochrome p450 enzymes to form hydroxyeicosatetraenoic and epoxyeicosatrienoic acid ethanolamides J Pharmacol Exp Ther 321 590 597 10.1124/jpet.107.119321
    • (2007) J Pharmacol Exp Ther , vol.321 , pp. 590-597
    • Snider, N.T.1    Kornilov, A.M.2    Kent, U.M.3    Hollenberg, P.F.4
  • 194
    • 0027524747 scopus 로고
    • Benzene metabolism by reconstituted cytochromes P450 2B1 and 2E1 and its modulation by cytochrome b5, microsomal epoxide hydrolase, and glutathione transferases: Evidence for an important role of microsomal epoxide hydrolase in the formation of hydroquinone
    • 10.1006/taap.1993.1185
    • R Snyder T Chepiga CS Yang H Thomas K Platt F Oesch 1993 Benzene metabolism by reconstituted cytochromes P450 2B1 and 2E1 and its modulation by cytochrome b5, microsomal epoxide hydrolase, and glutathione transferases: evidence for an important role of microsomal epoxide hydrolase in the formation of hydroquinone Toxicol Appl Pharmacol 122 172 181 10.1006/taap.1993.1185
    • (1993) Toxicol Appl Pharmacol , vol.122 , pp. 172-181
    • Snyder, R.1    Chepiga, T.2    Yang, C.S.3    Thomas, H.4    Platt, K.5    Oesch, F.6
  • 195
    • 33947375240 scopus 로고    scopus 로고
    • Action of epoxyeicosatrienoic acids on cellular function
    • 10.1152/ajpcell.00402.2006
    • AA Spector AW Norris 2007 Action of epoxyeicosatrienoic acids on cellular function Am J Physiol Cell Physiol 292 C996 C1012 10.1152/ajpcell.00402.2006
    • (2007) Am J Physiol Cell Physiol , vol.292
    • Spector, A.A.1    Norris, A.W.2
  • 196
    • 2942579253 scopus 로고    scopus 로고
    • Polymorphisms in human soluble epoxide hydrolase: Effects on enzyme activity, enzyme stability, and quaternary structure
    • 10.1016/j.abb.2004.05.003
    • PK Srivastava VK Sharma DS Kalonia DF Grant 2004 Polymorphisms in human soluble epoxide hydrolase: effects on enzyme activity, enzyme stability, and quaternary structure Arch Biochem Biophys 427 164 169 10.1016/j.abb.2004.05.003
    • (2004) Arch Biochem Biophys , vol.427 , pp. 164-169
    • Srivastava, P.K.1    Sharma, V.K.2    Kalonia, D.S.3    Grant, D.F.4
  • 198
    • 0036713678 scopus 로고    scopus 로고
    • Stereochemical features of the hydrolysis of 9, 10-epoxystearic acid catalysed by plant and mammalian epoxide hydrolases
    • 10.1042/BJ20011778
    • S Summerer A Hanano S Utsumi M Arand F Schuber E Blee 2002 Stereochemical features of the hydrolysis of 9, 10-epoxystearic acid catalysed by plant and mammalian epoxide hydrolases Biochem J 366 471 480 10.1042/BJ20011778
    • (2002) Biochem J , vol.366 , pp. 471-480
    • Summerer, S.1    Hanano, A.2    Utsumi, S.3    Arand, M.4    Schuber, F.5    Blee, E.6
  • 199
    • 0028027503 scopus 로고
    • Review of the metabolic fate of styrene
    • 10.3109/10408449409020138
    • SJ Sumner TR Fennell 1994 Review of the metabolic fate of styrene Crit Rev Toxicol 24 1 S11 S33 10.3109/10408449409020138
    • (1994) Crit Rev Toxicol , vol.24 , Issue.1
    • Sumner, S.J.1    Fennell, T.R.2
  • 200
    • 0037123925 scopus 로고    scopus 로고
    • Inhibition of vascular smooth muscle cell migration by cytochrome p450 epoxygenase-derived eicosanoids
    • 10.1161/01.RES.0000017727.35930.33
    • J Sun X Sui JA Bradbury DC Zeldin MS Conte JK Liao 2002 Inhibition of vascular smooth muscle cell migration by cytochrome p450 epoxygenase-derived eicosanoids Circ Res 90 1020 1027 10.1161/01.RES.0000017727.35930.33
    • (2002) Circ Res , vol.90 , pp. 1020-1027
    • Sun, J.1    Sui, X.2    Bradbury, J.A.3    Zeldin, D.C.4    Conte, M.S.5    Liao, J.K.6
  • 201
    • 33747875667 scopus 로고    scopus 로고
    • Involvement of the 5-lipoxygenase/leukotriene A4 hydrolase pathway in 7, 12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis in hamster cheek pouch, and inhibition of carcinogenesis by its inhibitors
    • 10.1093/carcin/bgl039
    • Z Sun S Sood N Li D Ramji P Yang RA Newman CS Yang X Chen 2006 Involvement of the 5-lipoxygenase/leukotriene A4 hydrolase pathway in 7, 12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis in hamster cheek pouch, and inhibition of carcinogenesis by its inhibitors Carcinogenesis 27 1902 1908 10.1093/carcin/bgl039
    • (2006) Carcinogenesis , vol.27 , pp. 1902-1908
    • Sun, Z.1    Sood, S.2    Li, N.3    Ramji, D.4    Yang, P.5    Newman, R.A.6    Yang, C.S.7    Chen, X.8
  • 202
    • 43949116261 scopus 로고    scopus 로고
    • Distribution and expression of soluble epoxide hydrolase in human brain
    • 10.1369/jhc.2008.950659
    • P Sura R Sura AE Enayetallah DF Grant 2008 Distribution and expression of soluble epoxide hydrolase in human brain J Histochem Cytochem 56 551 559 10.1369/jhc.2008.950659
    • (2008) J Histochem Cytochem , vol.56 , pp. 551-559
    • Sura, P.1    Sura, R.2    Enayetallah, A.E.3    Grant, D.F.4
  • 203
    • 47949133301 scopus 로고    scopus 로고
    • Antinociception produced by 14,15-epoxyeicosatrienoic acid is mediated by the activation of {beta}-endorphin and Met-enkephalin in the rat ventrolateral periaqueductal gray
    • Terashvili M, Tseng LF, Wu HE, Narayanan J, Hart LM, Falck JR, Pratt PF, Harder DR (2008) Antinociception produced by 14,15-epoxyeicosatrienoic acid is mediated by the activation of {beta}-endorphin and Met-enkephalin in the rat ventrolateral periaqueductal gray. J Pharmacol Exp Ther 326:614-622
    • (2008) J Pharmacol Exp Ther , vol.326 , pp. 614-622
    • Terashvili, M.1    Tseng, L.F.2    Wu, H.E.3    Narayanan, J.4    Hart, L.M.5    Falck, J.R.6    Pratt, P.F.7    Harder, D.R.8
  • 204
    • 0035146853 scopus 로고    scopus 로고
    • Crystal structure of human leukotriene A(4) hydrolase, a bifunctional enzyme in inflammation
    • 10.1038/84117
    • MM Thunnissen P Nordlund JZ Haeggstrom 2001 Crystal structure of human leukotriene A(4) hydrolase, a bifunctional enzyme in inflammation Nat Struct Biol 8 131 135 10.1038/84117
    • (2001) Nat Struct Biol , vol.8 , pp. 131-135
    • Thunnissen, M.M.1    Nordlund, P.2    Haeggstrom, J.Z.3
  • 206
    • 24644432418 scopus 로고    scopus 로고
    • Lipid sulfates and sulfonates are allosteric competitive inhibitors of the N-terminal phosphatase activity of the mammalian soluble epoxide hydrolase
    • 10.1021/bi050842g
    • KL Tran PA Aronov H Tanaka JW Newman BD Hammock C Morisseau 2005 Lipid sulfates and sulfonates are allosteric competitive inhibitors of the N-terminal phosphatase activity of the mammalian soluble epoxide hydrolase Biochemistry 44 12179 12187 10.1021/bi050842g
    • (2005) Biochemistry , vol.44 , pp. 12179-12187
    • Tran, K.L.1    Aronov, P.A.2    Tanaka, H.3    Newman, J.W.4    Hammock, B.D.5    Morisseau, C.6
  • 207
    • 24044555525 scopus 로고    scopus 로고
    • Epoxide hydrolase and CYP2C9 polymorphisms, cigarette smoking, and risk of colorectal carcinoma in the Nurses' Health Study and the Physicians' Health Study
    • 10.1002/mc.20112
    • GJ Tranah AT Chan E Giovannucci J Ma C Fuchs DJ Hunter 2005 Epoxide hydrolase and CYP2C9 polymorphisms, cigarette smoking, and risk of colorectal carcinoma in the Nurses' Health Study and the Physicians' Health Study Mol Carcinog 44 21 30 10.1002/mc.20112
    • (2005) Mol Carcinog , vol.44 , pp. 21-30
    • Tranah, G.J.1    Chan, A.T.2    Giovannucci, E.3    Ma, J.4    Fuchs, C.5    Hunter, D.J.6
  • 208
    • 0028243028 scopus 로고
    • Crystallization and preliminary X-ray crystallographic studies of recombinant human leukotriene A4 hydrolase complexed with bestatin
    • 10.1006/jmbi.1994.1341
    • H Tsuge H Ago M Aoki M Furuno M Noma M Miyano M Minami T Izumi T Shimizu 1994 Crystallization and preliminary X-ray crystallographic studies of recombinant human leukotriene A4 hydrolase complexed with bestatin J Mol Biol 238 854 856 10.1006/jmbi.1994.1341
    • (1994) J Mol Biol , vol.238 , pp. 854-856
    • Tsuge, H.1    Ago, H.2    Aoki, M.3    Furuno, M.4    Noma, M.5    Miyano, M.6    Minami, M.7    Izumi, T.8    Shimizu, T.9
  • 209
    • 0032478134 scopus 로고    scopus 로고
    • Semifunctional site-specific mutants affecting the hydrolytic half-reaction of microsomal epoxide hydrolase
    • 10.1021/bi9727388
    • HF Tzeng LT Laughlin RN Armstrong 1998 Semifunctional site-specific mutants affecting the hydrolytic half-reaction of microsomal epoxide hydrolase Biochemistry 37 2905 2911 10.1021/bi9727388
    • (1998) Biochemistry , vol.37 , pp. 2905-2911
    • Tzeng, H.F.1    Laughlin, L.T.2    Armstrong, R.N.3
  • 210
    • 0022355540 scopus 로고
    • Differential stereoselectivity of cytochromes P-450b and P-450c in the formation of naphthalene and anthracene 1, 2-oxides. the role of epoxide hydrolase in determining the enantiomer composition of the 1, 2-dihydrodiols formed
    • PJ van Bladeren JM Sayer DE Ryan PE Thomas W Levin DM Jerina 1985 Differential stereoselectivity of cytochromes P-450b and P-450c in the formation of naphthalene and anthracene 1, 2-oxides. The role of epoxide hydrolase in determining the enantiomer composition of the 1, 2-dihydrodiols formed J Biol Chem 260 10226 10235
    • (1985) J Biol Chem , vol.260 , pp. 10226-10235
    • Van Bladeren, P.J.1    Sayer, J.M.2    Ryan, D.E.3    Thomas, P.E.4    Levin, W.5    Jerina, D.M.6
  • 211
    • 0031683973 scopus 로고    scopus 로고
    • Limonene-1, 2-epoxide hydrolase from Rhodococcus erythropolis DCL14 belongs to a novel class of epoxide hydrolases
    • MJ van der Werf KM Overkamp JA de Bont 1998 Limonene-1, 2-epoxide hydrolase from Rhodococcus erythropolis DCL14 belongs to a novel class of epoxide hydrolases J Bacteriol 180 5052 5057
    • (1998) J Bacteriol , vol.180 , pp. 5052-5057
    • Van Der Werf, M.J.1    Overkamp, K.M.2    De Bont, J.A.3
  • 212
    • 33646084392 scopus 로고    scopus 로고
    • Diversity and biocatalytic potential of epoxide hydrolases identified by genome analysis
    • 10.1128/AEM.72.4.2905-2917.2006
    • B van Loo J Kingma M Arand MG Wubbolts DB Janssen 2006 Diversity and biocatalytic potential of epoxide hydrolases identified by genome analysis Appl Environ Microbiol 72 2905 2917 10.1128/AEM.72.4.2905-2917.2006
    • (2006) Appl Environ Microbiol , vol.72 , pp. 2905-2917
    • Van Loo, B.1    Kingma, J.2    Arand, M.3    Wubbolts, M.G.4    Janssen, D.B.5
  • 213
    • 34249938084 scopus 로고    scopus 로고
    • Cytotoxic oxysterols induce caspase-independent myelin figure formation and caspase-dependent polar lipid accumulation
    • 10.1007/s00418-006-0268-0
    • A Vejux E Kahn F Menetrier T Montange J Lherminier JM Riedinger G Lizard 2007 Cytotoxic oxysterols induce caspase-independent myelin figure formation and caspase-dependent polar lipid accumulation Histochem Cell Biol 127 609 624 10.1007/s00418-006-0268-0
    • (2007) Histochem Cell Biol , vol.127 , pp. 609-624
    • Vejux, A.1    Kahn, E.2    Menetrier, F.3    Montange, T.4    Lherminier, J.5    Riedinger, J.M.6    Lizard, G.7
  • 214
    • 0141676333 scopus 로고    scopus 로고
    • Cell surface expression and bile acid transport function of one topological form of m-epoxide hydrolase
    • 10.1016/j.bbrc.2003.08.074
    • P von Dippe QS Zhu D Levy 2003 Cell surface expression and bile acid transport function of one topological form of m-epoxide hydrolase Biochem Biophys Res Commun 309 804 809 10.1016/j.bbrc.2003.08.074
    • (2003) Biochem Biophys Res Commun , vol.309 , pp. 804-809
    • Von Dippe, P.1    Zhu, Q.S.2    Levy, D.3
  • 215
    • 0035155638 scopus 로고    scopus 로고
    • Crystal structure of phosphoserine phosphatase from Methanococcus jannaschii, a hyperthermophile, at 1.8 A resolution
    • 10.1016/S0969-2126(00)00558-X
    • W Wang R Kim J Jancarik H Yokota SH Kim 2001 Crystal structure of phosphoserine phosphatase from Methanococcus jannaschii, a hyperthermophile, at 1.8 A resolution Structure 9 65 71 10.1016/S0969-2126(00)00558-X
    • (2001) Structure , vol.9 , pp. 65-71
    • Wang, W.1    Kim, R.2    Jancarik, J.3    Yokota, H.4    Kim, S.H.5
  • 216
    • 0036301579 scopus 로고    scopus 로고
    • Structural characterization of the reaction pathway in phosphoserine phosphatase: Crystallographic "snapshots" of intermediate states
    • 10.1016/S0022-2836(02)00324-8
    • W Wang HS Cho R Kim J Jancarik H Yokota HH Nguyen IV Grigoriev DE Wemmer SH Kim 2002 Structural characterization of the reaction pathway in phosphoserine phosphatase: crystallographic "snapshots" of intermediate states J Mol Biol 319 421 431 10.1016/S0022-2836(02)00324-8
    • (2002) J Mol Biol , vol.319 , pp. 421-431
    • Wang, W.1    Cho, H.S.2    Kim, R.3    Jancarik, J.4    Yokota, H.5    Nguyen, H.H.6    Grigoriev, I.V.7    Wemmer, D.E.8    Kim, S.H.9
  • 217
    • 0019887824 scopus 로고
    • The hepatic microsomal biotransformation of delta 5-steroids to 5 alpha, 6 beta-glycols via alpha- and beta-epoxides
    • T Watabe M Kanai M Isobe N Ozawa 1981 The hepatic microsomal biotransformation of delta 5-steroids to 5 alpha, 6 beta-glycols via alpha- and beta-epoxides J Biol Chem 256 2900 2907
    • (1981) J Biol Chem , vol.256 , pp. 2900-2907
    • Watabe, T.1    Kanai, M.2    Isobe, M.3    Ozawa, N.4
  • 218
    • 0022967855 scopus 로고
    • Hepatic microsomal cholesterol epoxide hydrolase: Selective inhibition by detergents and separation from xenobiotic epoxide hydrolase
    • 10.1016/0006-291X(86)90778-3
    • T Watabe N Ozawa H Ishii K Chiba A Hiratsuka 1986 Hepatic microsomal cholesterol epoxide hydrolase: selective inhibition by detergents and separation from xenobiotic epoxide hydrolase Biochem Biophys Res Commun 140 632 637 10.1016/0006-291X(86)90778-3
    • (1986) Biochem Biophys Res Commun , vol.140 , pp. 632-637
    • Watabe, T.1    Ozawa, N.2    Ishii, H.3    Chiba, K.4    Hiratsuka, A.5
  • 220
    • 0034052794 scopus 로고    scopus 로고
    • Environmental and genetic determinants of aflatoxin-albumin adducts in the Gambia
    • 10.1002/(SICI)1097-0215(20000401)86:1<1::AID-IJC1>3.0.CO;2-I
    • CP Wild F Yin PC Turner I Chemin B Chapot M Mendy H Whittle GD Kirk AJ Hall 2000 Environmental and genetic determinants of aflatoxin-albumin adducts in the Gambia Int J Cancer 86 1 7 10.1002/(SICI)1097-0215(20000401)86:1<1::AID- IJC1>3.0.CO;2-I
    • (2000) Int J Cancer , vol.86 , pp. 1-7
    • Wild, C.P.1    Yin, F.2    Turner, P.C.3    Chemin, I.4    Chapot, B.5    Mendy, M.6    Whittle, H.7    Kirk, G.D.8    Hall, A.J.9
  • 221
    • 0030612585 scopus 로고    scopus 로고
    • Modulation of cholestane-3 beta, 5 alpha, 6 beta-triol toxicity by butylated hydroxytoluene, alpha-tocopherol and beta-carotene in newborn rat kidney cells in vitro
    • 10.1079/BJN19970165
    • AM Wilson RM Sisk NM O'Brien 1997 Modulation of cholestane-3 beta, 5 alpha, 6 beta-triol toxicity by butylated hydroxytoluene, alpha-tocopherol and beta-carotene in newborn rat kidney cells in vitro Br J Nutr 78 479 492 10.1079/BJN19970165
    • (1997) Br J Nutr , vol.78 , pp. 479-492
    • Wilson, A.M.1    Sisk, R.M.2    O'Brien, N.M.3
  • 222
    • 32944481037 scopus 로고    scopus 로고
    • Chemical genomic screening for methylation-silenced genes in gastric cancer cell lines using 5-aza-2′-deoxycytidine treatment and oligonucleotide microarray
    • 10.1111/j.1349-7006.2006.00136.x
    • S Yamashita Y Tsujino K Moriguchi M Tatematsu T Ushijima 2006 Chemical genomic screening for methylation-silenced genes in gastric cancer cell lines using 5-aza-2′-deoxycytidine treatment and oligonucleotide microarray Cancer Sci 97 64 71 10.1111/j.1349-7006.2006.00136.x
    • (2006) Cancer Sci , vol.97 , pp. 64-71
    • Yamashita, S.1    Tsujino, Y.2    Moriguchi, K.3    Tatematsu, M.4    Ushijima, T.5
  • 223
    • 34250795603 scopus 로고    scopus 로고
    • Epidermal lipoxygenase products of the hepoxilin pathway selectively activate the nuclear receptor PPARalpha
    • 10.1007/s11745-007-3054-4
    • Z Yu C Schneider WE Boeglin AR Brash 2007 Epidermal lipoxygenase products of the hepoxilin pathway selectively activate the nuclear receptor PPARalpha Lipids 42 491 497 10.1007/s11745-007-3054-4
    • (2007) Lipids , vol.42 , pp. 491-497
    • Yu, Z.1    Schneider, C.2    Boeglin, W.E.3    Brash, A.R.4
  • 225
    • 0029889723 scopus 로고    scopus 로고
    • Biochemical characterization of the human liver cytochrome P450 arachidonic acid epoxygenase pathway
    • 10.1006/abbi.1996.0229
    • DC Zeldin CR Moomaw N Jesse KB Tomer J Beetham BD Hammock S Wu 1996 Biochemical characterization of the human liver cytochrome P450 arachidonic acid epoxygenase pathway Arch Biochem Biophys 330 87 96 10.1006/abbi.1996.0229
    • (1996) Arch Biochem Biophys , vol.330 , pp. 87-96
    • Zeldin, D.C.1    Moomaw, C.R.2    Jesse, N.3    Tomer, K.B.4    Beetham, J.5    Hammock, B.D.6    Wu, S.7
  • 227
    • 38549145416 scopus 로고    scopus 로고
    • Genetic variation in cytochrome P450 2J2 and soluble epoxide hydrolase and risk of ischemic stroke in a Chinese population
    • 10.1097/FPC.0b013e3282f313e8
    • L Zhang H Ding J Yan R Hui W Wang GE Kissling DC Zeldin DW Wang 2008 Genetic variation in cytochrome P450 2J2 and soluble epoxide hydrolase and risk of ischemic stroke in a Chinese population Pharmacogenet Genomics 18 45 51 10.1097/FPC.0b013e3282f313e8
    • (2008) Pharmacogenet Genomics , vol.18 , pp. 45-51
    • Zhang, L.1    Ding, H.2    Yan, J.3    Hui, R.4    Wang, W.5    Kissling, G.E.6    Zeldin, D.C.7    Wang, D.W.8
  • 230
    • 34247605460 scopus 로고    scopus 로고
    • Suppression of 5-lipoxygenase gene is involved in triptolide-induced apoptosis in pancreatic tumor cell lines
    • GX Zhou XL Ding JF Huang H Zhang SB Wu 2007 Suppression of 5-lipoxygenase gene is involved in triptolide-induced apoptosis in pancreatic tumor cell lines Biochim Biophys Acta 1770 1021 1027
    • (2007) Biochim Biophys Acta , vol.1770 , pp. 1021-1027
    • Zhou, G.X.1    Ding, X.L.2    Huang, J.F.3    Zhang, H.4    Wu, S.B.5
  • 231
    • 1242269741 scopus 로고    scopus 로고
    • Regulation of human microsomal epoxide hydrolase gene (EPHX1) expression by the transcription factor GATA-4
    • QS Zhu B Qian D Levy 2004 Regulation of human microsomal epoxide hydrolase gene (EPHX1) expression by the transcription factor GATA-4 Biochim Biophys Acta 1676 251 260
    • (2004) Biochim Biophys Acta , vol.1676 , pp. 251-260
    • Zhu, Q.S.1    Qian, B.2    Levy, D.3
  • 232
    • 0034651639 scopus 로고    scopus 로고
    • Structure of Aspergillus niger epoxide hydrolase at 1.8 A resolution: Implications for the structure and function of the mammalian microsomal class of epoxide hydrolases
    • 10.1016/S0969-2126(00)00087-3
    • J Zou BM Hallberg T Bergfors F Oesch M Arand SL Mowbray TA Jones 2000 Structure of Aspergillus niger epoxide hydrolase at 1.8 A resolution: implications for the structure and function of the mammalian microsomal class of epoxide hydrolases Structure 8 111 122 10.1016/S0969-2126(00)00087-3
    • (2000) Structure , vol.8 , pp. 111-122
    • Zou, J.1    Hallberg, B.M.2    Bergfors, T.3    Oesch, F.4    Arand, M.5    Mowbray, S.L.6    Jones, T.A.7
  • 233
    • 0035061382 scopus 로고    scopus 로고
    • A polymorphism in the gene for microsomal epoxide hydrolase is associated with pre-eclampsia
    • 10.1136/jmg.38.4.234
    • PL Zusterzeel WH Peters W Visser KJ Hermsen HM Roelofs EA Steegers 2001 A polymorphism in the gene for microsomal epoxide hydrolase is associated with pre-eclampsia J Med Genet 38 234 237 10.1136/jmg.38.4.234
    • (2001) J Med Genet , vol.38 , pp. 234-237
    • Zusterzeel, P.L.1    Peters, W.H.2    Visser, W.3    Hermsen, K.J.4    Roelofs, H.M.5    Steegers, E.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.