Epoxide hydrolases: Mechanisms, inhibitor designs, and biological roles

Annual Review of Pharmacology and Toxicology

Volumn 45, Issue , 2005, Pages 311-333

  Morisseau, Christophe ^a   Hammock, Bruce D ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

hydrolase fold family; Epoxy eicosatrienoic acids; Hydroxyl alkyl enzyme intermediate; Hypertension; N,N dialkyl ureas

Indexed keywords

EPOXIDE; EPOXIDE HYDROLASE; HYDROLASE INHIBITOR;

ALLOSTERISM; AMINO ACID SEQUENCE; CATALYSIS; ENZYME INHIBITOR INTERACTION; ENZYME MECHANISM; GENOTOXICITY; HUMAN; HYDRATION; HYDROPHOBICITY; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; REACTION ANALYSIS; REVIEW; SYSTEMATIC REVIEW; TOXICOKINETICS;

ANIMALS; DRUG DESIGN; EPOXIDE HYDROLASES; HUMANS; PROTEASE INHIBITORS;

MAMMALIA;

EID: 13844316739     PISSN: 03621642     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.pharmtox.45.120403.095920     Document Type: Review

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