Soluble epoxide hydrolase is a susceptibility factor for heart failure in a rat model of human disease

Nature Genetics

Volumn 40, Issue 5, 2008, Pages 529-537

  Monti, Jan ^a,b   Fischer, Judith ^a   Paskas, Svetlana ^a   Heinig, Matthias ^a,c   Schulz, Herbert ^a   Gösele, Claudia ^a   Heuser, Arnd ^a,b   Fischer, Robert ^a,b   Schmidt, Cosima ^a   Schirdewan, Alexander ^b   Gross, Volkmar ^a   Hummel, Oliver ^a   Maatz, Henrike ^a   Patone, Giannino ^a   Saar, Kathrin ^a   Vingron, Martin ^c   Weldon, Steven M ^d   Lindpaintner, Klaus ^e   Hammock, Bruce D ^f   Rohde, Klaus ^a   Dietz, Rainer ^a,b   Cook, Stuart A ^g   Schunck, Wolf Hagen ^a   Luft, Friedrich C ^a,b   Hubner, Norbert ^a   more..

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

^d BOEHRINGER INGELHEIM PHARMACEUTICALS INC   (United States)

^e F HOFFMANN LA ROCHE LTD   (Switzerland)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EPOXIDE HYDROLASE; EPOXYICOSATRIENOIC ACID; PROTEIN EPHX2; TRANSCRIPTION FACTOR AP 1;

ANIMAL MODEL; ARTICLE; BINDING SITE; CHROMOSOME 15; CONTROLLED STUDY; DNA POLYMORPHISM; ENZYME ACTIVITY; FEMALE; GENE DELETION; GENE EXPRESSION PROFILING; GENE FUNCTION; GENE IDENTIFICATION; GENE SEQUENCE; GENETIC LINKAGE; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HEART ARRHYTHMIA; HEART FAILURE; HEART HEMODYNAMICS; HEART PROTECTION; HUMAN; HYDROLYSIS; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; SPONTANEOUSLY HYPERTENSIVE HEART FAILURE RAT;

MUS; RATTUS;

EID: 42649105447     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.129     Document Type: Article

References (49)