Anandamide metabolism by human liver and kidney microsomal cytochrome P450 enzymes to form hydroxyeicosatetraenoic and epoxyeicosatrienoic acid ethanolamides

Journal of Pharmacology and Experimental Therapeutics

Volumn 321, Issue 2, 2007, Pages 590-597

  Snider, Natasha T ^a   Kornilov, Andrei M ^b,c   Kent, Ute M ^a   Hollenberg, Paul F ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b Cayman Chemical Company   (United States)

^c INSTITUTE OF BIOORGANIC CHEMISTRY AND PETROCHEMISTRY   (Ukraine)

Author keywords

[No Author keywords available]

Indexed keywords

20 HYDROXYICOSATETRAENOIC ACID; AMIDE; ANANDAMIDE; CYTOCHROME P450; DRUG METABOLITE; EPOXIDE HYDROLASE; EPOXYICOSATRIENOIC ACID; ETHANOLAMIDE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG INHIBITION; DRUG METABOLISM; DRUG STRUCTURE; ENZYME METABOLISM; EPOXIDATION; HUMAN; HUMAN TISSUE; INCUBATION TIME; KIDNEY MICROSOME; KINETICS; LIVER MICROSOME; OXYGENATION; PRIORITY JOURNAL; PROTEIN ANALYSIS;

8,11,14-EICOSATRIENOIC ACID; ARACHIDONIC ACIDS; CYTOCHROME P-450 ENZYME SYSTEM; EPOXY COMPOUNDS; HUMANS; HYDROGEN-ION CONCENTRATION; HYDROXYEICOSATETRAENOIC ACIDS; KIDNEY; KINETICS; MICROSOMES, LIVER; POLYUNSATURATED ALKAMIDES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 34247281597     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.107.119321     Document Type: Article

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