Structural characterization of the reaction pathway in phosphoserine phosphatase: Crystallographic "snapshots" of intermediate states

Journal of Molecular Biology

Volumn 319, Issue 2, 2002, Pages 421-431

  Wang, Weiru ^a   Cho, Ho S ^b   Kim, Rosalind ^b   Jancarik, Jaru ^a   Yokota, Hisao ^b   Nguyen, Henry H ^b   Grigoriev, Igor V ^a   Wemmer, David E ^a,b   Kim, Sung Hou ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

Associative mechanism; Dissociative mechanism; Phosphoaspartyl enzyme intermediate; Phosphoserine phosphatase; Phosphotransfer, phospho monoester hydrolysis

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ISOENZYME; PHOSPHATASE; PHOSPHATE; PHOSPHOSERINE; PHOSPHOSERINE PHOSPHATASE; PROTEIN ALF3; PROTEIN BEF3; PROTEIN DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DISSOCIATION; ENZYME ACTIVE SITE; ENZYME BINDING; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME SUBSTRATE; METHANOCOCCUS JANNASCHII; MOLECULAR MIMICRY; MUTATION; NONHUMAN; PHOSPHATE TRANSPORT; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FAMILY; PROTEIN FOLDING; REACTION ANALYSIS; SEQUENCE HOMOLOGY; STRUCTURE ANALYSIS;

METHANOCALDOCOCCUS JANNASCHII; METHANOCOCCUS;

EID: 0036301579     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(02)00324-8     Document Type: Article

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