Catalytic triad of microsomal epoxide hydrolase: Replacement of Glu404 with Asp leads to a strongly increased turnover rate

Biochemical Journal

Volumn 337, Issue 1, 1999, Pages 37-43

  Arand, Michael ^a   Müller, Frank ^a   Mecky, Astrid ^a   Hinz, Willy ^a,b   Urban, Phillipe ^b   Pompon, Denis ^b   Kellner, Roland ^a   Oesch, Franz ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; ASPARAGINE; CARBON 14; CYANOGEN BROMIDE; EPOXIDE HYDROLASE; ESTER; GLUTAMINE; HISTIDINE; MICROSOME ENZYME; PEPTIDE; STEARIC ACID; STYRENE OXIDE;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME KINETICS; GENE EXPRESSION; GENETIC RECOMBINATION; HYDROLYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; SACCHAROMYCES CEREVISIAE; SEQUENCE ANALYSIS;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; ASPARTIC ACID; BASE SEQUENCE; CATALYTIC DOMAIN; DNA PRIMERS; EPOXIDE HYDROLASES; GLUTAMIC ACID; KINETICS; MICROSOMES, LIVER; MOLECULAR SEQUENCE DATA; RATS; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID;

ANIMALIA; SACCHAROMYCES CEREVISIAE;

EID: 2442731907     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3370037     Document Type: Article

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