Structure of Rhodococcus erythropolis limonene-1,2-epoxide hydrolase reveals a novel active site

EMBO Journal

Volumn 22, Issue 11, 2003, Pages 2583-2592

  Arand, Michael ^a   Hallberg, B Martin ^b,c   Zou, Jinyu ^b   Bergfors, Terese ^b   Oesch, Franz ^d   Van der Werf, Mariët J ^e,f   De Bont, Jan A M ^e,g   Jones, T Alwyn ^b   Mowbray, Sherry L ^g  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UPPSALA UNIVERSITY   (Sweden)

^c JOHANNES GUTENBERG UNIVERSITY   (Germany)

^d WAGENINGEN UNIVERSITY   (Netherlands)

^e SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

^f ALBANOVA UNIVERSITY CENTER   (Sweden)

^g TNO   (Netherlands)

Author keywords

Crystal structure; Enantioselectivity; Epoxide hydrolase; Mechanism; Monoterpene degradation

Indexed keywords

BACTERIAL ENZYME; LIMONENE 1,2 EPOXIDE HYDROLASE; SELENOMETHIONINE; UNCLASSIFIED DRUG; VALPROMIDE;

ALPHA HELIX; ARTICLE; BETA SHEET; CATALYSIS; CHEMICAL REACTION; CRYSTAL STRUCTURE; DETOXIFICATION; DRUG PROTEIN BINDING; ENANTIOSELECTIVITY; ENZYME ACTIVE SITE; ENZYME METABOLISM; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; NONHUMAN; PRIORITY JOURNAL; REACTION ANALYSIS; RHODOCOCCUS ERYTHROPOLIS; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; EPOXIDE HYDROLASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN SUBUNITS; RECOMBINANT PROTEINS; RHODOCOCCUS; SEQUENCE HOMOLOGY, AMINO ACID;

ACTINOBACTERIA (CLASS); BACTERIA (MICROORGANISMS); RHODOCOCCUS; RHODOCOCCUS ERYTHROPOLIS; UNCULTURED ACTINOMYCETE;

EID: 0037863737     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdg275     Document Type: Article

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