Neural interactions with materials

Frontiers in Bioscience

Volumn 14, Issue 2, 2009, Pages 769-795

  Dalton, Paul Donald ^a,b   Mey, Joerg ^c  

^a Deutsche Wollforschungsinstitut   (Germany)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

^c RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

3D cell culture; Cell material interactions; Guided cell growth; Nerve cells; Review

Indexed keywords

BIOMATERIAL;

ANIMAL; CYTOLOGY; HUMAN; NERVE CELL; REVIEW; TISSUE ENGINEERING;

ANIMALS; BIOCOMPATIBLE MATERIALS; HUMANS; NEURONS; TISSUE ENGINEERING;

EID: 63849196740     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: 10.2741/3277     Document Type: Review

References (260)

1. S. Ramón y Cajal: Estudios sobre la degeneración y regeneración del sistema nervioso. Imprenta hihos de Nicolás Moya, Madrid (1914)
2. M. G. Fehlings, D. C. Baptiste: Current status of clinical trials for acute spinal cord injury. Injury 36, S-B113-S-B122 (2005) (Pubitemid 40903127)
3. J. W. Fawcett: Overcoming inhibition in the damaged spinal cord. J. Neurotrauma 23, 371-383(2006) (Pubitemid 43739277)
4. W. Gomes-Leal, D. J. Corkill, M. A. Freire, C. W. Picanço-Diniz, V. H. Perry: Astrocytosis, microglia activation, oligodendrocyte degeneration, and pyknosis following acute spinal cord injury. Exp. Neurol. 190, 456-467(2004) (Pubitemid 39516940)
5. P. G. Popovich: Alterations in immune cell phenotype and function after experimental spinal cord injury. J. Neurotrauma 18, 954-966(2001)
6. G. Raivich, M. Bohatschek, C. U. A. Kloss, A. Werner, L. L. Jones, G. W. Kreutzberg: Neuroglial activation repertoire in the injured brain: graded response, molecular mechanisms and cues to physiological function. Brain Res. Rev. 30, 77-105(1999) (Pubitemid 29331517)
7. J. C. Fleming, M. D. Norenberg, D. A. Ramsay, G. A. Dekaban, A. E. Marcillo, A. D. Saenz, M. Paswuale-Styles, W. D. Dietrich, L. C. Weaver: The cellular inflammatory response in human spinal cords after injury. Brain 129, 3249-3269(2006) (Pubitemid 44871440)
8. I. Dusart, M. E. Schwab: Secondary cell death and the inflammatory reaction after dorsal hemisection of the rat spinal cord. Eur. J. Neurosci. 6, 712-724(1994) (Pubitemid 24143919)
9. S. L. Carlson, M. E. Parrish, J. E. Springer, K. Doty, L. Dossett: Acute inflammatory response in spinal cord following impact injury. Exp. Neurol. 151, 77-88(1998) (Pubitemid 28223857)
10. R. Gonzalez, J. Glaser, M. T. Liu, T. E. Lane, H. S. Keirstead: Reducing inflammation decreases secondary degeneration and functional deficit after spinal cord injury. Exp. Neurol. 184, 456-463(2003) (Pubitemid 37444053)
11. W. Young, J. Kume-Kick, S. Constantini: Glucocorticoid therapy of spinal cord injury. Ann. N. Y. Acad. Sci. 743, 241-265(1994)
12. P. G. Popovich, J. F. Reinhard Jr, E. M. Flanagan, B. T. Stokes: Elevation of the neurotoxin quinolinic acid occurs following spinal cord trauma. Brain Res. 633, 348-352(1994) (Pubitemid 24021282)
13. S. Thanos, J. Mey: Type-specific stabilization and target-dependent survival of regenerating ganglion cells in the retina of adult rats. J. Neurosci. 15, 1057-1079(1995)
14. H. Kager, W. J. Wadman, G. G. Somjen: Conditions for the triggering of spreading depression studied with computer simulations. J. Neurophysiol. 88, 2700-2712(2002) (Pubitemid 35346069)
15. C. Arango-Davila, M. Escobar-Betancourt, G. P. Cardona-Gómez, H. Pimienta-Jiménez: Fisiopatología de la isquemia cerebral focal: aspectos básicos y proyección a la clínica. Rev. Neurol. 39, 156-165(2004) (Pubitemid 39128135)
16. G. Denson, M. Fujikawa: Confusion between neuronal apoptosis and activation of programmed cell death mechnisms in acute becrotic insults. Trends Neurosci. 23, 410-411(2000)
17. O. Lazarov-Spiegler, O. Rapalino, G. Agranow, M. Schwartz: Restricted inflammatory reaction in the CNS: a key impediment to axonal regeneration? Mol. Med. Today 4, 337-342(1998) (Pubitemid 28368554)
18. M. Schwartz, G. Moalem, R. Leibowitz-Amit, I. R. Cohen: Innate and adaptive immune responses can be beneficial for CNS repair. Trends Neurosci. 22, 295-299(1999) (Pubitemid 29307803)
19. P. E. Batchelor, M. J. Porritt, P. Martinello, C. L. Parish, G. T. Liberatore, G. A. Donnan, D. W. Howells: Macrophages and microglia produce local trophic gradients that stimulate axonal sprouting toward but not beyond the wound edge. Mol. Cell. Neurosci. 21, 436-453(2004) (Pubitemid 36062730)
20. S. Jander, F. Lausberg, G. Stoll: Differential recruitment of CD8+ macrophages during Wallerian degeneration in the peripheral and central nervous system. Brain Pathol. 11, 27-38(2001)
21. R. Kiefer, B. C. Kieseier, G. Stoll, H. P. Hartung: The role of macrophages in immune-mediated damage to the peripheral nervous system. Progr. Neurobiol. 64, 109-127(2001) (Pubitemid 32195409)
22. S. Lacroix, L. Chang, S. Rose-John, M. H. Tuszynski: Delivery of hyper-interleukin-6 to the injured spinal cord increases neutrophil and macrophage infiltration and inhibits axonal growth. J. Comp. Neurol. 454, 213-228(2002) (Pubitemid 35423832)
23. Y. Li, Y. Sauvé, D. Li, R. D. Lund, G. Raisman: Transplanted olfactory ensheathing cells promote regeneration of cut adult rat optic nerve axons. J. Neurosci. 23, 7783-7788(2003) (Pubitemid 37052346)
24. A. C. Lee, V. M. Yu, J. B. I. Lowe, M. J. Brenner, D. A. Hunter, S. E. Mackinnon, S. E. Sakiyama-Elbert: Controlled release of nerve growth factor enhances sciatic nerve regeneration. Exp. Neurol. 184, 295-303(2003) (Pubitemid 37444039)
25. M. Makwana, G. Raivich: Molecular mechanisms in successful peripheral regeneration. FEBS J. 272, 2628-2638(2005) (Pubitemid 40825411)
26. J. F. Tello: La influencia del neurotropismo en la regeneración de los centros nerviosos. Trab. Lab. Invest. Biol. 9, 123-159(1911)
27. P. J. Horner, F. H. Gage: Regenerating the damaged central nervous system. Nature 407, 963-970(2000)
28. S. David, A. Aguayo: Axonal regeneration into peripheral nervous system "bridges" after central nervous system injury in adult rats. Science 214, 931-933(1981) (Pubitemid 12220099)
29. M. Vidal-Sanz, G. M. Bray, M. P. Villégaz-Pérez, S. Thanos, A. Aguayo: Axonal regeneration and synapse formation in the superior colliculus by retinal ganglion cells in the adult rat. J. Neurosci. 7, 2894-2909(1987)
30. S. David, S. Lacroix: Molecular approaches to spinal cord repair. Ann. Rev. Neurosci. 26, 411-440(2003) (Pubitemid 37064940)
31. M. T. Filbin: Myelin-associated inhibitors of axonal regeneration in the adult mammalian CNS. Nat. Rev. Neurosci. 4, 1-11(2003)
32. J. Corcoran, P. L. So, R. D. Barber, K. J. Vincent, N. D. Mazarakis, K. A. Mitrophanous, S. M. Kingsman, M. Maden: Retinoic acid receptor beta2 and neurite outgrowth in the adult mouse spinal cord in vitro. J. Cell Sci. 115, 3779-3786(2002) (Pubitemid 35203604)
33. J. Mey, S. Thanos: Ontogenetic changes in the regenerative ability of chick retinal ganglion cells as revealed by organ explants. Cell Tissue Res. 264, 347-355(1991)
34. J. W. Fawcett, R. A. Asher: The glial scar and central nervous system repair. Brain Res. Bull. 39, 377-391(1999) (Pubitemid 29385505)
35. F. J. Liuzzi, R. J. Lasek: Astrocytes block axonal regeneration in mammals by activating the physiological stop pathway. Science 237, 642-645(1987)
36. P. Bovolenta, I. Fernaud-Espinosa, R. Méndez-Otero, M. Nieto-Sampredro: Neurite outgrowth inhibitor of gliotic brain tissue. Mode of action and cellular localization, studied with specific monoclonal antibodies. Eur. J. Neurosci. 9, 977-989(1997) (Pubitemid 27226461)
37. T. G. Bush, N. Puvanachandra, C. H. Horner, A. Polito, T. Ostenfeld, C. N. Svendsen, L. Mucke, M. H. Johnson, M. V. Sofroniew: Leukocyte infiltration, neuronal degeneration, and neurite outgrowth after ablation of scar-forming, reactive astrocytes in adult transgenic mice. Neuron 23, 297-308(1999) (Pubitemid 29315725)
38. C. C. Stichel, H. W. Müller: The CNS lesion scar: new vistas on an old regeneration barrier. Cell Tissue Res. 294, 1-9(1998) (Pubitemid 28442277)
39. J. R. Faulkner, J. E. Herrmann, M. J. Woo, K. E. Tansey, N. B. Doan, M. V. Sofroniew: Reactive astrocytes protect tisue and preserve function after spinal cord injury. J. Neurosci. 24, 2143-2155(2004) (Pubitemid 38314546)
40. C. M. Liberto, P. J. Albrecht, L. M. Herx, V. W. Yong, S. W. Levison: Pro-regenerative properties of cytokineactivated astrocytes. J. Neurochem. 89, 1092-1100(2004)
41. M. S. Chen, A. B. Huber, M. E. van der Haar, M. Frank, L. Schnell, A. A. Spillmann, F. Christ, M. E. Schwab: Nogo-A is a myelin-associated neurite outgrowth inhibitor and an antigen for monoclonal antibody IN-1. Nature 403, 434-439(2000) (Pubitemid 30073093)
42. D. M. McTigue, P. Wei, B. T. Stokes: Proliferation of NG2-positive cells and altered oligodendrocyte numbers in the contused rat spinal cord. J. Neurosci. 21, 3392-3400(2001) (Pubitemid 32422804)
43. J. Mey, D. Morasutti, G. Brook, R. H. Liu, Y. P. Zhang, G. Koopmans, P. McCaffery: Retinoic acid synthesis by a population of NG-2 positive cells in the injured spinal cord. Eur. J. Neurosci. 21, 1555-1568(2005) (Pubitemid 40646601)
44. F. Bajrovic, M. Srpcic, J. Sketelj: Schwann cell dependence of regenerating rat sensory neurons is inversely related to the quality of axon growth substratum. J. Neuropathol. Exp. Neurol. 60, 65-74(2001) (Pubitemid 32097006)
45. I. Kohama, K. L. Lankford, J. Preiningerova, F. A. White, T. L. Vollmer, J. D. Kocsis: Transplantation of cyropreserved adult human Schwann cells enhances axonal conduction in demyelinated spinal cord. J. Neurosci. 21, 944-950(2001) (Pubitemid 32163135)
46. G. A. Brook, D. Plate, R. Franzen, D. Martin, G. Moonen, J. Schoenen, A. B. Schmitt, J. Noth, W. Nacimiento: Spontaneous longitudinally orientated aconal regeneration is asociated with the Schwann cell framework within the lesion site following spinal cord compression injury of the rat. J. Neurosci. Res. 53, 51-65(1998) (Pubitemid 28308981)
47. S. C. Barnett, L. Chang: Olfactory ensheathing cells and CNS repair: going solo or in need of a friend? Trends Neurosci. 27, 54-60(2004) (Pubitemid 38040070)
48. R. J. M. Franklin, S. C. Barnett: Olfactory ensheathing cells and CNS regeneration: the sweet smell of success? Neuron 28, 15-18(2000)
49. G. Raisman: Olfactory ensheathing cells - another miracle cure for spinal cord injury? Nat. Rev. Neurosci. 2, 369-375(2001)
50. D. K. Resnick, C. Cechvala, Y. Yan, B. P. Witwer, D. Sun, S. Zhang: Adult olfactory ensheathing cell transplantation for acute spinal cord injury. J. Neurotrauma 20, 279-285(2003) (Pubitemid 36373825)
51. S. Thanos, C. Pavlidis, J. Mey, H.-J. Thiel: Specific transcellular staining of microglia in the adult rat after experimentally induced degeneration of carbocyanine-filled retinal ganglion cells. Exp. Eye Res. 55, 101-117(1992)
52. A. Werner, C. U. A. Kloss, J. Walter, G. W. Kreutzberg, G. Raivich: Intercellular adhesion molecule-1 (ICAM-1) in the mouse facial motor nucleus after axonal injury and during regeneration. J. Neurocytol. 27, 219-232(1998) (Pubitemid 28416908)
53. G. Raivich, M. Bohatschek, A. Werner, L. L. Jones, M. Galiano, C. U. A. Kloss, X. Z. Zhu, K. Pfeffer, Z. Q. Liu: Lymphocyte infiltration in the injured brain: role of proinflammatory cytokines. J. Neurosci. Res. 72, 726-733(2003) (Pubitemid 36666266)
54. M. B. Graeber, W. J. Streit, G. W. Kreutzberg: Identity of ED2-positive perivascular cells in rat brain. J. Neurosci. Res. 22, 103-106(1989) (Pubitemid 19067258)
55. H. S. Taskinen, T. Olsson, A. Bucht, M. Khademi, L. Svelander, M. Röyttä: Peripheral nerve injury induces endoneurial expression of IFN-gamma, IL-10 and TNF-alpha mRNA. J. Neuroimmunol. 102, 17-25(2000)
56. P. Hu, E. M. McLachlan: Distinct functional types of macrophages in dorsal root ganglia and spinal nerves proximal to sciatic and spinal nerve transections in the rat. Exp. Neurol. 184, 590-605(2003) (Pubitemid 38182790)
57. K. Vass, W. F. Hickey, R. E. Schmidt, H. Lassmann: Bone marrow-derived elements in the peripheral nervous system. Lab. Invest. 69, 275-282(1993)
58. G. K. Tofaris, P. H. Patterson, K. R. Jessen, R. Mirsky: Denervated Schwann cells attract macrophages by secretion of leukemia inhibitory factor (LIF) and monocyte chemoattractant protein-1 in a process regulated by interleukin-6 and LIF. J. Neurosci. 22, 6696-6703(2002) (Pubitemid 35386425)
59. F. González-Scarano, G. Baltuch: Microglia as mediators of inflammatory and degenerative diseases. Ann. Rev. Neurosci. 22, 219-240(1999) (Pubitemid 29144887)
60. M. Ma, P. Wei, T. Wei, R. M. Ransohoff, L. B. Jakeman: Enhanced axonal growth into a spinal cord contusion injury site in a strain of mouse (129X1/SvJ) with a diminished inflammatory response. J. Comp. Neurol. 474, 469-468(2004)
61. S. Thanos, J. Mey, M. Wild: Treatment of the adult retina with microglia-suppressing factors retards axotomyinduced neuronal degradation and enhances axonal regeneration in vivo and in vitro. J. Neurosci. 13, 455-466(1993) (Pubitemid 23045132)
62. L. Steinman, R. Martin, C. Bernard, P. Conlon, J. R. Oksenberg: Multiple sclerosis: Deeper understanding of its pathogenesis reveals new targets for therapy. Ann. Rev. Neurosci. 25, 491-505(2000) (Pubitemid 34748026)
63. M. Nieto-Sampredro, J. E. Collazos-Castro, J. S. Taylor, G. Gudino-Cabrera, E. Verdú-Navarro, J. I. Pascual-Piédrola, R. Insausti-Serrano: Trauma en el sistema nervioso central y su reparación. Rev. Neurol. 35, 534-552(2002) (Pubitemid 36267780)
64. J. L. Ridet, S. K. Malhotra, A. Privat, F. H. Gage: Reactive astrocytes: cellular and molecular cues to biological function. Trends Neurosci. 20, 570-577(1997) (Pubitemid 27508969)
65. I. Fernaud-Espinosa, M. Nieto-Sampredro, P. Bovolenta: Differential activation of microglia and astrocytes in aniso-and isomorphic gliotic tissue. Glia 4, 277-291(1993)
66. W. J. Streit, S. L. Semple-Rowland, S. D. Hurley, R. C. Miller, P. G. Popovich, B. T. Stokes: Cytokine mRNA profiles in contuse spinal cord and axotomized facial nucleus suggest a beneficial role for inflammation and gliosis. Exp. Neurol. 152, 74-87(1998) (Pubitemid 28366968)
67. S. S. Scherer, J. L. Salzer: Axon-Schwann cell interactions during peripheral nerve degeneration and regeneration. In Jessen, K. R. & Richardson, W. D. (eds), Glial cell development - basic principles and clinical relevance. Oxford University Press, Oxford, pp. 299-330 (2001)
68. M. T. Filbin, J. Qiu, D. Cai: Glial influences on axonal regeneration. In Jessen, K. R. & Richardson, W. D. (eds), Glial cell development - basic principles and clinical relevance. Oxford University Press, Oxford, pp. 279-298 (2001)
69. R. P. Lisak, D. Skundric, B. Bealmear, S. Ragheb: The role of cytokines in Schwann cell damage, protection, and repair. J. Infect. Dis. 176, S173-S179 (1997) (Pubitemid 27505885)
70. K. S. Bedi, J. Winter, M. Berry, J. Cohen: Adult rat dorsal root ganglion neurons extend neurites on predegenerated but not on normal peripheral nerves in vitro. Eur. J. Neurosci. 4, 193-200(1992)
71. M. C. Brown, E. R. Lunn, V. H. Perry: Poor growth of mammalian motor and sensory axons into intact proximal nerve stumps. Eur. J. Neurosci. 3, 1366-1369(1991)
72. Y. Li, P. M. Field, G. Raisman: Death of oligodendrocytes and microglial phagocytosis of myelin precede immigration of Schwann cells into the spinal cord. J. Neurocytol. 28, 417-427(1999) (Pubitemid 30321019)
73. S. L. Shuman, J. C. Bresnahan, M. S. Beattie: Apoptosis of microglia and oligodendrocytes after spinal cord contusion in rats. J. Neurosci. Res. 50, 798-808(1997) (Pubitemid 27518276)
74. S. Casha, W. R. Yu, M. G. Fehlings: Oligodendroglial apoptosis occurs along degenerating axons and is associated with FAS and p75 expression following spinal cord injury in the rat. Neuroscience 103, 203-218(2001) (Pubitemid 32304360)
75. A. Minagar, E. G. Toledo, J. S. Alexander, R. E. Kelley: Pathogenesis of brain and spinal cord atrophy in multiple sclerosis. J. Neuroimaging 14, 5S-10S (2004) (Pubitemid 38781406)
76. F. Hu, S. M. Strittmatter: Regulating axon growth within the postnatal central nervous system. Semin. Perinatol. 28, 371-378(2004) (Pubitemid 40037563)
77. M. D. Benson, M. I. Romero, M. E. Lush, Q. R. Lu, M. Henkemeyer, L. F. Parada: Ephrin-B3 is a myelin-based inhibitor of neurite outgrowth. Proc. Natl. Acad. Sci. USA 102, 11131-11136(2005)
78. J. Strelau, K. Unsicker: GDNF family members and their receptors: expression and function in two oligodendroglial cell lines representing distinct stages of oligodendroglial development. Glia 26, 291-301(1999) (Pubitemid 29257191)
79. A. Wilkins, S. Chandrean, A. Compston: A role for oligodendrocyte-derived IGF-1 in trophic support of cortical neurons. Glia 36, 48-57(2001)
80. J. Mey, L. Henkes: Retinoic acid enhances leukemia inhibitory factor expression in OLN-93 oligodendrocytes. Cell Tissue Res. 310, 155-161(2002) (Pubitemid 36015566)
81. X. Dai, L. D. Lercher, P. M. Clinton, Y. Du, D. L. Livingston, C. Vieira, L. Yang, M. M. Shen, C. F. Dreyfus: The trophic role of oligodendrocytes in the basal forebrain. J. Neurosci. 23, 5846-5853(2005)
82. R. Franzen, D. Martin, A. Daloze, G. Moonen, J. Schoenen: Grafts of meningeal fibroblasts in adult rat spinal cord lesion promote axonal regrowth. Neuroreport 10, 1551-1556(1999) (Pubitemid 29354345)
83. M. Sensenbrenner, J. C. Deloulme, C. Gensburger: Proliferation of neuronal precursor cells from the central nervous system in culture. Rev. Neurosci. 5, 43-53(1994) (Pubitemid 24134521)
84. D. A. Charytoniuk, E. Traiffort, E. Pinard, O. Issertial, J. Seylaz, M. Ruat: Distribution of bone morphogenetic protein and bone morphogenetic protein receptor transcripts in the rodent nervous system and up-regulation of bone morphogenetic protein receptor type II in hippocampal dentate gyrus in a rat model of global cerebral ischemia. Neuroscience 100, 33-43(2000) (Pubitemid 30670299)
85. R. W. Pelton, M. E. Dickinson, H. L. Moses, B. L. Hogan: In situ hybridization analysis of TGF beta3 RNA expression during mouse development: comparative studies with TGF beta1 and beta1. Development 110, 609-620(1990) (Pubitemid 20330536)
86. K. A. Sullivan, E. L. Feldman: Immunohistochemical localization of insulin-like growth factor-II (IGF-II) and IGF-binding protein-2 during development of the rat brain. Endocrinology 135, 540-547(1994)
87. A. Nishiyama, X. H. Lin, N. Giese, C. H. Heldin, W. B. Stallcup: Co-localization of NG2 proteoglycan and PDGF alpha-receptor on O2A progenitor cells in the developing rat brain. J. Neurosci. Res. 43, 299-314(1996) (Pubitemid 26054018)
88. A. M. Butt, J. Kiff, P. Hubbard, M. Berry: Synantocytes: New functions for novel NG2 expressing glia. J. Neurocytol. 31, 551-565(2002) (Pubitemid 37383741)
89. A. Nishiyama, M. Watanabe, Z. Yang, J. Bu: Identity, distribution, and development of polydendrocytes: NG2-expressing glial cells. J. Neurocytol. 31, 437-455(2002) (Pubitemid 37378257)
90. L. L. Jones, Y. Yamaguchi, W. B. Stallcup, M. H. Tuszynski: NG2 is a major chondroitin sulfate proteoglyan produced after spinal cord injury and is expressed by macrophages and oligodendrocyte progenitors. J. Neurosci. 22, 2792-2803(2002) (Pubitemid 37465828)
91. J. M. Levine: Increased Expression of the NG2 chondroitin-sulfate proteoglycan after brain injury. J. Neurosci. 14, 4716-4730(1994) (Pubitemid 24237894)
92. C. L. Dou, J. M. Levine: Inhibition of neurite growth by the NG2 chondroitin sulfate proteoglycan. J. Neurosci. 14, 7616-7628(1994) (Pubitemid 24379769)
93. L. L. Jones, D. Sajed, M. H. Tuszynski: Axonal regeneration through regions of chondroitin sulfate proteoglycan deposition after spinal cord injury: a balance of permissiveness and inhibition. J. Neurosci. 23, 9276-9288(2003) (Pubitemid 37323026)
94. M. J. Politis, D. Ederle, P. S. Spencer: Tropism in nerve regeneration in vivo. Attraction of regenerating axons by diffusible factors derived from cells in distal nerve stumps of transected peripheral nerves. Brain Res. 253, 1-12(1982) (Pubitemid 13212212)
95. J. Y. Sheu, D. J. Kulhanek, F. P. Eckenstein: Differential patterns of ERK and STAT3 phosphorylation after sciatic nerve transection in the rat. Exp. Neurol. 166, 392-402(2000)
96. N. Q. McDonald, M. V. Chao: Structural determinants of neuritrophin action. J. Biol. Chem. 270, 19669-19672(2005)
97. J. G. Boyd, T. Gordon: Neurotrophic factors and their receptors in axonal regeneration and functional recovery after peripheral nerve injury. Mol. Neurobiol. 27, 277-324(2003)
98. M. V. Chao, P. Casaccia-Bonnefil, B. Carter, A. Chittka, H. Kong, S. O. Yoon: Neurotrophin receptors: mediators of life and death. Brain Res. Rev. 26, 295-301(2000)
99. W. J. Friedman, L. A. Greene: Neurotrophin signaling via trks and p75. Exp. Cell Res. 253, 131-142(1999)
100. H. Thoenen: Neurotrophins and neuronal plasticity. Science 270, 593-598(2000)
101. H. H. Althaus, C. Richter-Landsberg: Glial cells as targets and producers of neurotrophins. Int. Rev. Cytol. 197, 203-277(2000) (Pubitemid 30148250)
102. B. Connor, M. Dragunow: The role of neuronal growth factors in neurodegenerative disorders of the human brain. Brain Res. Rev. 27, 1-39(1998) (Pubitemid 28300281)
103. K. D. Dougherty, C. F. Dreyfus, I. B. Black: Brainderived neurotrophic factor in astrocytes, oligodendrocytes, and microglia/macrophages after spinal cord injury. Neurobiol. Disease 7, 574-585(2000) (Pubitemid 32044283)
104. C. Gillen, C. Korfhage, H. W. Müller: Gene expression in nerve regeneration. Neuroscientist 3, 112-122(1997) (Pubitemid 127532804)
105. F. Hefti: Neurotrophic factor therapy for nervous system degenerative diseases. J. Neurobiol. 25, 1418-1435(1994) (Pubitemid 24325066)
106. H. Thoenen, M. Sendtner: Neurotrophins: from enthusiastic expectations through sobering experiences to rational therapeutic approaches. Nat. Neurosci. Suppl. 5, 1046-1050(2002) (Pubitemid 35247196)
107. M. S. Airaksinen, M. Saarma: The GDNF family: signalling, biological functions and therapeutic value. Nat. Rev. Neurosci. 3, 383-394(2002) (Pubitemid 135706635)
108. H. Sariola, M. Saarma: Novel functions and signalling pathways for GDNF. J. Cell Sci. 116, 3855-3862(2003) (Pubitemid 37279301)
109. D. L. H. Bennett, T. J. Boucher, M. P. Armanini, K. T. Poulsen, G. J. Michael, J. V. Priestley, H. S. Phillips, S. B. McMahon, D. L. Shelton: The glial cell line-derived neurotrophic factor family receptor components are differentially regulated within sensory neurons after nerve injury. J. Neurosci. 20, 427-437(2000) (Pubitemid 30220528)
110. R. Lemke, M. Hartlage-Rübsamen, R. Schliebs: Differential injury-dependent glial expression of interleukins-1-Beta, alpha, and interleukin-6 in rat brain. Glia 27, 75-87(1999) (Pubitemid 29311508)
111. M. Nakamura, R. A. Houghtling, L. MacArthur, B. Bayer, B. S. Bregman: Differences in cytokine gene expression profile between acute and secondary injury in adult rat spinal cord. Exp. Neurol. 184, 313-325(2003) (Pubitemid 37444041)
112. P. C. Heinrich, I. Behrmann, G. Müller-Newen, F. Schaper, L. Graeve: Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway. Biochem. J. 334, 297-314(1998) (Pubitemid 28448572)
113. F. W. Schwaiger, G. Hager, A. B. Schmitt, A. Horvat, G. Hager, R. Streif, C. Spitzer, S. Garnal, S. Breuer, G. A. Brook, W. Nacimiento, G. W. Kreutzberg: Peripheral but not central axotomy induces changes in Janus kinases (JAK) and signal transducers and activators of transcription (STAT). Eur. J. Neurosci. 12, 1165-1176(2000) (Pubitemid 30224223)
114. B. Stark, T. Carlstedt, M. Risling: Distribution of TGF-beta, the TGF-beta type I receptor and the R-II recptor in peripheral nerves and mechanoreceptors; observations on changes after traumatic injury. Brain Res. 913, 47-56(2001) (Pubitemid 32786930)
115. M. Reiss: Transforming growth factor-Beta and cancer: a love-hate relationship? Oncol. Res. 9, 447-457(1997)
116. G. Grasso, A. Sfacteria, A. Cerami, M. Brines: Erythropoietin as a tissue-protective cytokine in brain injury: what do we know and where do we go? Neuroscientist 10, 93-98(2004) (Pubitemid 38372870)
117. T. Yasuhara, T. Shingo, I. Data: The potential role of vascular endothelial growth factor in the central nervous system. Rev. Neurosci. 15, 293-307(2004) (Pubitemid 39388339)
118. J. M. Krum, A. Khaibullina: Inhibition of endogenous VEGF impedes revascularization and astroglial proliferation: roles for VEGF in brain repair. Exp. Neurol. 181, 241-257(2003) (Pubitemid 36629245)
119. J. M. Rosenstein, N. Mani, A. Khaibullina, J. M. Krum: Neurotrophic effects of vascular endothelial growth factor on organotypic cortical explants and primary cortical neurons. J. Neurosci. 23, 11036-11044(2003) (Pubitemid 37548937)
120. V. C. Asensio, I. L. Campbell: Chemokines in the CNS. Trends Neurosci. 22, 504-512(1999)
121. H. S. Taskinen, M. Röyttä: Increases expression of chemokines (MCP-1, KIP-1-alpha, RANTES) after peripheral nerve transection. J. Peripheral Nervous System 5, 75-81(2000) (Pubitemid 30451709)
122. F. E. Perrin, S. Lacroix, M. Avilés-Trigueros, S. David: Involvement of monocyte chemoattractant protein-1, macrophage inflammatory protein-1-alpha and interleukin-1-Beta in Wallerian degeneration. Brain 128, 854-866(2005) (Pubitemid 40516922)
123. V. Appay, S. L. Rowland-Jones. RANTES: a versatile and controversial chemokine. Trends Immunol. 22, 83-87(2001). (Pubitemid 32667526)
124. I. Barakat-Walter: Role of thyroid hormones and their receptors in peripheral nerve regeneration. J. Neurobiol. 40, 541-559(1999) (Pubitemid 29400059)
125. D. García-Ovejero, S. Veiga, L. M. García-Segura, L. L. Doncarlos: Glial expression of estrogen and androgen receptors after rat brain injury. J. Comp. Neurol. 450, 256-271(2002) (Pubitemid 34809996)
126. G. W. Jung, M. Spencer, T. F. Lue: Growth hormone enhynces regeneration of nitric oxide synthase-containing penile nerves after cavernous nerve neurotomy in rats. J. Urol. 160, 1899-1904(1998) (Pubitemid 128746783)
127. J. R. Keast: The autonomic nerve supply of male sex organs - an important target of circulating androgens. Behav. Brain Res. 105, 81-92(1999) (Pubitemid 29447614)
128. D. L. Behrmann, J. C. Bresnahan, M. S. Beattie: Modeling of acute spinal cord injury in the rat: neuroprotection and enhanced recovery with methylprednisolone, U-74006F and YM-14673. Exp. Neurol. 126, 61-75(1994) (Pubitemid 24131103)
129. K. J. Jones: Androgenic enhancement of motor neuron regeneration. Ann. N. Y. Acad. Sci. 743, 141-161(1994)
130. K. J. Jones, S. Coers, P. D. Storer, L. Tanzer, N. B. Kindermann: Androgenic regulation of the central glia response following nerve damage. J. Neurobiol. 40, 560-573(1999) (Pubitemid 29400060)
131. P. McCaffery, U. C. Dräger: Regulation of retinoic acid signaling in the embryonic nervous system: a master differentiation factor. Cytokine Growth Factor Rev. 11, 233-249(2000) (Pubitemid 30337462)
132. J. Corcoran, M. Maden: Nerve growth factor acts via retinoic acid synthesis to stimulate neurite outgrowth. Nat. Neurosci. 2, 307-308(1999) (Pubitemid 30491270)
133. J. Mey: A new target for CNS injury? The role of retinoic acid signaling after nerve lesions. J. Neurobiol. 66, 757-779(2006) (Pubitemid 43939198)
134. N. Zhelyaznik, J. Mey: Expression of retinoic acid receptors and retinoid X receptors after sciatic nerve injury. Neuroscience 141, 1761-1774(2006) (Pubitemid 44233131)
135. N. Zhelyaznik, K. Schrage, P. McCaffery, J. Mey: Activation of retinoic acid signaling after sciatic nerve injury: upregulation of cellular retinoid binding proteins. Eur. J. Neurosci. 18, 1033-1040(2003) (Pubitemid 37115025)
136. J. Corcoran, B. Shroot, J. Pizzey, M. Maden: The role of retinoic acid receptors in neurite outgrowth from different populations of embryonic mouse dorsal root ganglia. J. Cell Sci. 113, 2567-2574(2000) (Pubitemid 30601378)
137. K. Schrage, G. Koopmans, E. A. Joosten, J. Mey: Macrophages and neurons are targets of retinoic acid signaling after spinal cord contusion injury. Eur. J. Neurosci. 23, 285-295(2006)
138. O. Arrieta, R. García-Navarrete, S. Zúñiga, G. Ordóñez, A. Ortiz, G. Palencia, D. Morales-Espinosa, N. Hernández-Pedro, J. Sotelo: Retinoic acid increases tissue and plasma contents of nerve growth factor and prevents neuropathy in diabetic mice. Eur. J. Clin. Invest. 35, 201-297(2005)
139. M. O. Taha, M. Rosseto, M. M. Fraga, S. F. Mueller, D. J. Fagundes, N. F. Novo, A. Caricati-Neto: Effect of retinoic acid on tibial nerve regeneration after anastomosis in rats: histological and functional analysis. Transpl. Proc. 36, 404-408(2004) (Pubitemid 38407210)
140. L. F. Wong, P. K. Yip, A. Battaglia, J. Grist, J. Corcoran, M. Maden, M. Azzouz, S. M. Kingsman, A. J. Kingsman, N. D. Mazarakis, S. B. McMahon: Retinoic acid receptor Beta-2 promotes functional regeneration of sensory axons in the spinal cord. Nat. Neurosci. 9, 243-250(2006) (Pubitemid 43164548)
141. C. Ide, K. Tohyama, R. Yokota, T. Nitatori, S. Onodera: Schwann cell basal lamina and nerve regeneration. Brain Res. 288, 61-75(1983) (Pubitemid 14212694)
142. Z.-L. Chen, S. Strickland: Laminin g1 is critical for Schwann cell differentiation, axon myelination, and regeneration in the peripheral nerve. J. Cell Biol. 163, 889-899(2003) (Pubitemid 37517895)
143. K. Gelse, E. Pöschl, T. Aigner: Collagens - structure, function and biosynthesis. Adv. Drug Del. Rev. 55, 1531-1546(2003)
144. V. J. Tom, C. M. Doller, A. T. Malouf, J. Silver: Astrocyte-associated fibronectin is critical for axonal regeneration in adult white matter. J. Neurosci. 24, 9282-9290(2004) (Pubitemid 39426165)
145. J. Silver, J. H. Miller: Regeneration beyond the glial scar. Nat. Rev. Neurosci. 5, 146-156(2004) (Pubitemid 38160289)
146. B. Chamak, V. Morandi, M. Mallat: Brain macrophages stimulate neurite outgrowth and regeneration by secreting thrombospondin. J. Neurosci. Res. 38, 221-233(1994) (Pubitemid 24155739)
147. H. Colognato, P. D. Yurchenco: Form and function: The laminin family of heterotrimers. Dev. Dynamics 218, 213-234(2000) (Pubitemid 30349637)
148. J. Engel, E. Odermatt, A. Engel, J. A. Madri, H. Furthmayr, H. Rohde, R. Timpl: Shapes, domain organizations and flexibility of laminin and fibronectin, two multifunctional proteins of the extracellular matrix. J. Mol. Biol. 150, 97-120(1981)
149. U. Hersel, C. Dahmen, H. Kessler: RGD modified polymers: biomaterials for stimulated cell adhesion and beyond. Biomaterials 24, 4385-4415(2003) (Pubitemid 36960136)
150. M. Aumailley, B. Gayraud: Structure and biological activity of the extracellular matrix. J. Mol. Med. 76, 253-265(1998) (Pubitemid 28098711)
151. J. C. Schense, J. Bloch, P. Aebischer, J. A. Hubbell: Enzymatic incorporation of bioactive peptides into fibrin matrices enhances neurite extension. Nat. Biotech. 18, 415-419(2000) (Pubitemid 30217529)
152. J. C. Schense, J. A. Hubbell: Three-dimensional migration of neurites is mediated by adhesion site density and affinity. J. Biol. Chem. 275, 6813-6818(2000) (Pubitemid 30146220)
153. M. Borkenhagen, J. F. Clémence, H. Sigrist, P. Aebischer: Three dimensional extracellular matrix engineering in the nervous system. J Biomed Mater Res 40, 392-400(1998) (Pubitemid 28182882)
154. T. T. Yu, M. S. Shoichet: Guided cell adhesion and outgrowth in peptide-modified channels for neural tissue engineering. Biomaterials 26, 1507-1514(2005) (Pubitemid 39441383)
155. J. Graf, R. C. Ogle, F. A. Robey, M. Sasaki, G. R. Martin, Y. Yamada, H. K. Kleinman: A pentapeptide from the laminin B1 chain mediates cell adhesion and binds the 67 000 laminin receptor. Biochemistry 26, 6896-6900(1987) (Pubitemid 18006247)
156. S. P. Massia, S. S. Rao, J. A. Hubbell: Covalently immobilized laminin peptide Tyr-Ile-Gly-Ser-Arg (YIGSR) supports cell spreading and co-localization of the 67-kilodalton laminin receptor with alpha-actinin and vinculin. J Biol Chem 268, 8053-8059(1993) (Pubitemid 23120387)
157. J. Ranieri, R. Bellamkonda, E. Bekos, J. Gardella, H. Mathieu, L. Ruiz, P. Aebischer: Spatial control of neuronal cell attachment and differentiation on covalently patterned laminin oligopeptide substrates. Int J Dev Neurosci 725-735 (1994)
158. G. A. Silva, C. Czeisler, K. L. Niece, E. Beniash, D. A. Harrington, J. A. Kessler, S. I. Stupp: Selective differentiation of neural progenitor cells by high-epitope density nanofibers. Science 303, 1352-1355(2004) (Pubitemid 38269424)
159. K. Tashiro, G. C. Sephel, B. Weeks, M. Sasaki, G. R. Martin, H. K. Kleinman, Y. Yamada: A synthetic peptide containing the IKVAV sequence from the alpha chain of laminin mediates cell attachment, migration, and neurite outgrowth. J Biol Chem 264, 16174-16182(1989) (Pubitemid 19238381)
160. H. Kleinman, B. Weeks, F. Cannon, T. Sweeney, G. Sephel, B. Clement, M. Zain, M. Olson, M. Judker, B. Burrous: Identification of a 110-kDa non-integrin cell surface laminin-binding protein which recognizes an alpha chain neurite promoting peptide. Arch Biochem Biophys 290, 320-325(1991)
161. L. Luckenbill-Edds, C. Kaiser, T. Rodgers, D. Powell: Localization of 110 kDa receptor for laminin in brains of embryonic and postnatal mice. Cell Tissue Res 279, 371-377(1995)
162. Y. W. Tong, M. S. Shoichet: Enhancing the neuronal interaction on fluoropolymer surfaces with mixed peptides or spacer group linkers. Biomaterials 22, 1029-1034(2001) (Pubitemid 32229928)
163. S. Carbonetto, M. M. Gruver, D. C. Turner: Nerve fiber growth in culture on fibronectin, collagen and glycosaminoglycan substrates. J Neurosci 3, 2324-2335(1983) (Pubitemid 14248189)
164. N. Dubey, P. C. Letourneau, R. T. Tranquillo: Guided neurite elongation and schwann cell invasion into magnetically aligned collagen in simulated peripheral nerve regeneration. Exp Neurol 158, 338-350(1999) (Pubitemid 29382825)
165. D. Ceballos, X. Navarro, N. Dubey, G. Wendelschafer-Crabb, W. R. Kennedy, R. T. Tranquillo: Magnetically aligned collagen gel filling a collagen nerve guide improves peripheral nerve regeneration. Exp. Neurol. 158, 290-300(1999) (Pubitemid 29382821)
166. S. P. Baldwin, C. E. Krewson, W. M. Saltzman: PC12 aggregation and neurite growth in gels of collagen, laminin and fibronectin. Int J Dev Neurosci 14, 351-364(1996) (Pubitemid 26238176)
167. R. O. Labrador, M. Butý, X. Navarro: Influence of collagen and laminin gels concentration on nerve regeneration after resection and tube repair. Exp Neurol 149, 243-252(1998) (Pubitemid 28091034)
168. R. Midha, C. A. Munro, P. D. Dalton, C. H. Tator, M. S. Shoichet: Growth factor enhancement of peripheral nerve regeneration through a novel synthetic hydrogel tube. J Neurosurg 99, 555-565(2003) (Pubitemid 37040419)
169. L. J. Chamberlain, I. V. Yannas, H. P. Hsu, G. Strichartz, M. Spector: Collagen-GAG substrate enhances the quality of nerve regeneration through collagen tubes up to level of autograft. Exp Neurol 154, 315-329(1998) (Pubitemid 29044204)
170. R.-Y. Liu, W. D. Snider: Different signaling pathways mediate regenerative versus developmental sensory axon growth. J. Neurosci. 21, RC164 (1-5) (2001)
171. S. Liu, G. Said, M. Tadie: Regrowth of the rostral spinal axons into the caudal ventral roots through a collagen tube implanted into hemisected adult rat spinal cord. Neurosurgery 49, 143-151(2001) (Pubitemid 32552592)
172. M. H. Spilker, I. V. Yannas, S. K. Kostyk, T. V. Norregaard, H. P. Hsu, M. Spector: The effects of tubulation on healing and scar formation after transection of the adult rat spinal cord. Restor Neurol Neurosci 18, 23-38(2001) (Pubitemid 32881791)
173. S. J. Taylor, J. W. McDonald, S. E. Sakiyama-Elbert: Controlled release of neurotrophin-3 from fibrin gels for spinal cord injury. J Control Release 98, 281-294(2004) (Pubitemid 38950737)
174. E. C. Tsai, P. D. Dalton, C. H. Tator, M. S. Shoichet: Matrix inclusion within synthetic hydrogel guidance channels improves specific supraspinal and local axonal regeneration after complete spinal cord transection. Biomaterials 27, 519-533(2006) (Pubitemid 41457254)
175. S. E. Sakiyama-Elbert, J. A. Hubbell: Controlled release of nerve growth factor from a heparin-containing fibrin-based cell ingrowth matrix. J Control Release 69, 149-158(2000)
176. N. Dubey, P. C. Letourneau, R. T. Tranquillo: Neuronal contact guidance in magnetically aligned fibrin gels: effect of variation in gel mechano-structural properties. Biomaterials 1065-1075 (2001) (Pubitemid 32229932)
177. Q. Yin, G. Kemp, L.-G. Yu, S. Wagstaff, S. Frostick: Neurotrophin-4 delivered by fibrin glue promotes peripheral nerve regeneration. Muscle Nerve 24, 345-351(2001) (Pubitemid 32172709)
178. E. Verdu, R. Labrador, F. Rodriguez, D. Ceballos, J. Fores, X. Navarro: Alignment of collagen and laminincontaining gels improve nerve regeneration within silicone tubes. Restor Neurol Neurosci 20, 169-179(2002) (Pubitemid 36098892)
179. A. Ramón-Cueto, G. W. Plant, J. Avila, M. B. Bunge: Long-distance axonal regeneration in the transected adult rat spinal cord is promoted by olfactory ensheathing glia transplants. J Neurosci 18, 3803-3815(1998) (Pubitemid 28225687)
180. X. M. Xu, A. Chen, V. Guénard, N. Kleitman, M. B. Bunge: Bridging Schwann cell transplants promote axonal regeneration from both the rostral and caudal stumps of transected adult rat spinal cord. J Neurocytol 26, 1-16(1997) (Pubitemid 27186757)
181. X. M. Xu, V. Guénard, N. Kleitman, M. B. Bunge: Axonal regeneration into Schwann cell-seeded guidance channels grafted into transected adult rat spinal cord. J Comp Neurol 351, 145-160(1995)
182. J. B. Phillips, V. R. King, Z. Ward, R. A. Porter, J. V. Priestley, R. A. Brown: Fluid shear in viscous fibronectin gels allows aggregation of fibrous materials for CNS tissue engineering. Biomaterials 25, 2769-2779(2004) (Pubitemid 38201302)
183. J. Priestley, M. Ramer, V. King, S. McMahon, R. Brown: Stimulating regeneration in the damaged spinal cord. J Physiol Paris 96, 123-133(2002) (Pubitemid 34087040)
184. T. A. Horbett: Principles underlying the role of adsorbed plasma-proteins in blood interactions with foreign materials. Cardiovasc Pathol 2, S137-S148 Suppl (1993)
185. F. Grinnell, M. K. Feld: Adsorption characteristics of plasma fibronectin in relationship to biological activity. J Biomed Mater Res 15, 363-381(1981) (Pubitemid 11159647)
186. F. Grinnell, M. K. Feld: Fibronectin adsorption on hydrophilic and hydrophobic surfaces detected by antibody-binding and analyzed during cell-adhesion in serum-containing medium. J Biol Chem 257, 4888-4893(1982)
187. R. Biran, K. Webb, M. D. Noble, P. A. Tresco: Surfactant-immobilized fibronectin enhances bioactivity and regulates sensory neurite outgrowth. J Biomed Mater Res 55, 1-12(2001) (Pubitemid 32157780)
188. S. Rogers, J. McCarthy, S. Palm, L. Furcht, P. Letourneau: Neuron-specific interactions with two neuritepromoting fragments of fibronectin. J Neurosci 5, 369-378(1985) (Pubitemid 15133154)
189. K. J. Tomaselli, C. H. Damsky, L. F. Reichardt: Interactions of a neural cell line (PC12) with laminin, collagen IV, and fibronectin: Identification of integrinrelated glycoproteins involved in attachment and process outgrowth. J Cell Biol 105, 2347-2358(1987) (Pubitemid 18019083)
190. D. Hall, K. Neugebauer, L. Reichardt: Embryonic neural retinal cell response to extracellular matrix proteins: developmental changes and effects of the cell substratum attachment antibody (CSAT). J Cell Biol 104, 623-634(1987) (Pubitemid 17024717)
191. Z. Sisková, W. Baron, H. de Vries, D. Hoekstra: Fibronectin impedes "myelin" sheet-directed flow in oligodendrocytes: a role for a beta 1 integrin-mediated PKC signaling pathway in vesicular trafficking. Mol Cell Neurosci 33, 150-9(2006) (Pubitemid 44415490)
192. A. Balgude, X. Yu, A. Szymanski, R. Bellamkonda: Agarose gel stiffness determines rate of DRG neurite extension in 3D cultures. Biomaterials 22, 1077-1084(2001) (Pubitemid 32229933)
193. R. Bellamkonda, J. Ranieri, N. Bouche, P. Aebischer: Hydrogel-based three-dimensional matrix for neural cells. J Biomed Mater Res 29, 663-671(1995)
194. X. Yu, R. Bellamkonda: Dorsal root ganglia neurite extension is inhibited by mechanical and chondroitin sulphate-rich interfaces. J Neurosci Res 66, 303-310(2001) (Pubitemid 32912300)
195. X. Cao, M. S. Shoichet: Defining the concentration gradient of nerve growth factor for guided neurite outgrowth. Neuroscience 103, 831-840(2001) (Pubitemid 32239344)
196. X. Cao, M. S. Shoichet: Investigating the synergistic effect of combined neurotrophic factor concentration gradients to guide axonal growth. Neuroscience 122, 381-389(2003) (Pubitemid 37410168)
197. G. L. Ming, H. J. Song, B. Berninger, C. E. Holt, M. Tessier-Lavigne: cAMP-dependent growth cone guidance by netrin-1. Neuron 19, 1225-1235(1997) (Pubitemid 28030542)
198. H. J. Song, G. L. Ming, M.-M. Poo: cAMP-induced switching in turning direction of nerve growth cones. Nature 388, 275-279(1997) (Pubitemid 27317971)
199. Y. Luo, M. S. Shoichet: A photolabile hydrogel for guided three dimensional cell growth and migration. Nat Mater 3, 249-253 (2004a)
200. R. Mumper, A. Hoffman, A. Puolakkainen, L. Bouchard, W. Gombotz: Calcium-alginate beads for the oral delivery of transforming growth factor-PI (TGF-p1): stabilization of TGF-PI by the addition of polyacrylic acid within acid-treated beads. J Control Release 30, 241-251(1994)
201. S. Chang, J. Rowley, G. Tobias, N. Genes, A. Roy, D. Mooney, C. Vacanti, L. Bonassar: Injection molding of chondrocyte/alginate constructs in the shape of facial implants. J Biomed Mater Res 55, 503-511(2001) (Pubitemid 32336280)
202. J. Rowley, D. Mooney: Alginate type and RGD density control myoblast phenotype. J Biomed Mater Res 60, 217-223(2002) (Pubitemid 34194582)
203. S. Wu, Y. Suzuki, M. Kitada, M. Kitaura, K. Kataoka, J. Takahashi, C. Ide, Y. Nishimura: Migration, integration, and differentiation of hippocampus-derived neurosphere cells after transplantation into injured rat spinal cord. Neurosci Lett 312, 173-176(2001) (Pubitemid 32972151)
204. H. F. Liang, M. H. Hong, R.-M. Ho, C.-K. Chung, Y.-H. Lin, C.-H. Chen, H.-W. Sung: Novel method Using a Temperature-Sensitive Polymer (Methylcellulose) to Thermally Gel Aqueous Alginate as a pH-Sensitive Hydrogel. Biomacromolecules 5, 1917-1925(2004) (Pubitemid 39335233)
205. Y. Suzuki, M. Kitaura, S. Wu, K. Kataoka, K. Suzuki, K. Endo, Y. Nishimura, C. Ide: Electrophysiological and horseradish peroxidase-tracing studies of nerve regeneration through alginate-filled gap in adult rat spinal cord. Neurosci Lett 318, 121-124(2002) (Pubitemid 34136024)
206. K. Suzuki, Y. Suzuki, M. Tanihara, K. Ohnishi, T. Hashimoto, K. Endo, Y. Nishimura: Reconstruction of rat peripheral nerve gap without sutures using freeze-dried alginate gel. J Biomed Mater Res 49, 528-533(2000) (Pubitemid 30030472)
207. M. Ohta, Y. Suzuki, H. Chou, N. Ishikawa, S. Suzuki, M. Tanihara, Y. Suzuki, Y. Mizushima, M. Dezawa, C. Ide: Novel heparin/alginate gel combined with basic fibroblast growth factor promotes nerve regeneration in rat sciatic nerve. J Biomed Mater Res 71 A, 661-668 (2004) (Pubitemid 39578680)
208. T. Hashimoto, Y. Suzuki, K. Suzuki, T. Nakashima, M. Tanihara, C. Ide: Review: Peripheral nerve regeneration using non-tubular alginate gel crosslinked with covalent bonds. J Mater Sci Mat Med 16, 503-509(2005) (Pubitemid 40884241)
209. G. T. Hermanson: Bioconjugate Techniques. Academic Press (1996)
210. S. Zhang, T. C. Holmes, M. Diperssio, R. O. Hynes, X. Su, A. Rich: Self-complementary oligopeptide matrices support mammalian cell attachment. Biomaterials 16, 1385(1995)
211. C. E. Semino, J. Kasahara, Y. Hayashi, S. Zhang: Entrapment of migrating hippocampal neural cells in three-dimensional peptide nanofiber scaffold. Tissue Engineering 10, 643-655(2004) (Pubitemid 38580284)
212. T. C. Holmes, S. Delacalle, X. Su, A. Rich, S. Zhang: Extensive neurite outgrowth and active neuronal synapses on peptide scaffolds. PNAS 97, 6278(2000)
213. J. Kisiday, M. Jin, B. Kurz, H. Hung, C. Semino, S. Zhang, A. Grodzinsky: Self-assembling peptide hydrogel fosters chondrocyte extracellular matrix production and cell division: Implications for cartilage tissue repair. PNAS 99, 9996-10001(2002) (Pubitemid 34831161)
214. S. Carbonetto, M. M. Gruver, D. C. Turner: Nerve fiber growth on defined hydrogel substrates. Science 216, 897-899(1982) (Pubitemid 12058820)
215. T. Adams-Kapur, M. S. Shoichet: Immobilized concentration gradients of nerve growth factor guide neurite outgrowth. J Biomed Mater Res 68 A, 235-243 (2004) (Pubitemid 38524717)
216. J. Kohn, R. S. Aloyz, J. G. Toma, M. Haak-Frendscho, F. D. Miller: Functionally anagonistic interactions between the TrkA and p75 neurotrophin receptors regulate sympathetic neuron growth and target innervation. J Neurosci 19, 5393-5408(1999) (Pubitemid 29300205)
217. E. C. Tsai, P. D. Dalton, M. S. Shoichet, C. H. Tator: Synthetic hydrogel guidance channels facilitate regeneration of adult rat brainstem motor axons after complete spinal cord transection. J. Neurotrauma 21, 789-804(2004) (Pubitemid 38880249)
218. T. K. Huang, G. L. Chang, H. S. Lin, F. R. Walter, L. Bunegin: Stress-strain relationship of the spinal cord of anesthetized cats. J Biomechanics 14, 269-276(1988)
219. P. D. Dalton, L. Flynn, M. S. Shoichet: Manufacture of poly (2-hydroxyethyl methacrylate-co-methyl methacrylate) hydrogel tubes for use as nerve guidance channels. Biomaterials 23, 3843-3851(2002) (Pubitemid 34828158)
220. R. L. Waddell, K. G. Marra, K. L. Collins, J. T. Leung, J. S. Doctor: Using PC12 cells to evaluate poly (caprolactone) and collagenous microcarriers for applications in nerve guide fabrication. Biotechnol Prog 19, 1767-1774(2003) (Pubitemid 37529213)
221. S. Gautier, M. Oudega, M. Fragoso, P. Chapon, G. Plant, M. Bunge, J.-M. Parel: Poly (alpha-hydroxyacids) for application in the spinal cord: Resorbability and biocompatibility with adult rat Schwann cells and spinal cord. J Biomed Mater Res 42, 642-654(1998) (Pubitemid 28503771)
222. M. Oudega, S. Gautier, P. Chapon, M. Fragoso, M. Bates, J.-M. Parel, M. Bunge: Axonal regeneration into Schwann cell grafts within resorbable poly (-hydroxyacid) guidance channels in the adult rat spinal cord. Biomaterials 22, 1125-1136(2001) (Pubitemid 32229937)
223. M. J. Roberts, M. D. Bentley, J. M. Harris: Chemistry for peptide and protein PEGylation. Adv Drug Del Rev 54, 459-476(2002) (Pubitemid 34615543)
224. J. Groll, Z. Ademovic, T. Ameringer, D. Klee, M. Moeller: Comparison of coatings from reactive star shaped PEG-stat-PPG prepolymers and grafted linear PEG for biological and medical applications. Biomacromolecules 6, 956-962(2005) (Pubitemid 40467842)
225. D. Branch, B. Wheeler, G. Brewer, D. Leckband: Long-term stability of grafted polyethylene glycol surfaces for use with microstamped substrates in neuronal cell culture. Biomaterials 22, 1035-1047(2001) (Pubitemid 32229929)
226. M. P. Lutolf, J. L. Lauer-Fields, H. G. Schmoekel, A. T. Metter, F. E. Weber, G. B. Fields, J. A. Hubbell: Synthetic matrix metalloproteinase-sensitive hydrogels for the conduction of tissue regeneration: Engineering cellinvasion characteristics. PNAS 100, 5413-5418(2003) (Pubitemid 36542719)
227. M. P. Lutolf, G. P. Raeber, A. H. Zisch, N. Tirelli, J. A. Hubbell: Cell-responsive synthetic hydrogels. Adv Mater 15, 888-892(2003)
228. M. J. Mahoney, K. S. Anseth: Three-dimensional growth and function of neural tissue in degradable polyethylene glycol hydrogels. Biomaterials 27, 2265-2274(2006) (Pubitemid 41774537)
229. C. E. Schmidt, V. R. Shastri, J. P. Vacanti, R. Langer: Stimulation of neurite outgrowth using an electrically conducting polymer. PNAS 94, 8948-8953(1997) (Pubitemid 27357762)
230. A. Kotwal, C. Schmidt: Electrical stimulation alters protein adsorption and nerve cell interactions with electrically conducting biomaterials. Biomaterials 22, 1055-1064(2001) (Pubitemid 32229931)
231. P. M. George, A. W. Lyckman, D. A. LaVan, A. Hegde, Y. Leung, R. Avasare, C. Testa, P. M. Alexander, R. Langer, M. Sur: Fabrication and biocompatibility of polypyrrole implants suitable for neural prosthetics. Biomaterials 26, 3511-3519(2005) (Pubitemid 40038145)
232. S. J. Chen, D. Y. Wang, C. W. Yuan, X. D. Wang, P. Y. Zhang, X. S. Gu: Template synthesis of the polypyrrole tube and its bridging in vivo sciatic nerve regeneration. J Mater Sci Lett 19, 2157-2159(2000)
233. J. M. Corey, E. L. Feldman: Substrate patterning: an emerging technology for the study of neuronal behavior. Exp Neurol 184, S89-S96 (2003) (Pubitemid 37345156)
234. P. C. Letourneau: Cell-to-substratum adhesion and guidance of axonal elongation. Dev Biol, 44, 92-101(1975)
235. H.-C. Tai, H. M. Buettner: Neurite outgrowth and growth cone morphology on micropatterned surfaces. Biotechnol Prog 14, 364-370(1998) (Pubitemid 28278816)
236. A. K. Vogt, L. Lauer, W. Knoll, A. Offenhäusser: Micropatterned substrates for the growth of functional neuronal networks of defined geometry. Biotechnol Prog 19, 1562-1568(2003) (Pubitemid 37250049)
237. H. X. Avci, P. Zelina, K. Thelen, G. E. Pollerberg: Role of cell adhesion molecule DM-GRASP in growth and orientation of retinal ganglion cell axons. Dev Biol 271, 291-305(2004) (Pubitemid 38833662)
238. D. Adams, E. Kao, C. Hypolite, M. Distefano, W.-S. Hu, P. Letourneau: Growth cones turn and migrate up an immobolized gradient of the laminin IKVAV peptide. J Neurobiol 62, 134-147(2005) (Pubitemid 39636384)
239. S. M. Smeal, R. Rabbitt, R. Biran, P. A. Tresco: Substrate curvature influences the direction of nerve outgrowth. Ann Biomed Eng 33, 376-382(2005) (Pubitemid 40536669)
240. L. N. Novikov, L. N. Novikova, A. Mosahebi, M. Wiberg, G. Terenghi, J.-O. Kellerth: A novel biodegradable implant for neuronal rescue and regeneration after spinal cord injury. Biomaterials 23, 3369-3376(2002) (Pubitemid 34615643)
241. C. Miller, S. Jeftinija, S. Mallapragada: Micropatterned Schwann cell-seeded biodegradable substrates significantly enhance neurite alignment and outgrowth. Tissue Engineering 7, 705-715(2001) (Pubitemid 34042303)
242. R. Yang, R. Murugan, S. Wang, S. Ramakrishna: Electrospinning of nano/micro scale poly (L-lactic acid) aligned fibers and their potential in neural tissue engineering. Biomaterials 26, 2603-2610(2005) (Pubitemid 39600712)
243. P. D. Dalton, D. Klee, M. Möller: Electrospinning with dual collection rings. Polymer 46, 611-614(2005) (Pubitemid 40091754)
244. E. Schnell, K. Klinkhammer, S. Balzer, G. Brook, D. Klee, P. D. Dalton, J. Mey: Guidance of glial cell migration and axonal growth on electrospun nanofibers of poly-ecaprolactone and a collagen/poly-e-caprolactone blend. Biomaterials 28, 3012-3025(2007) (Pubitemid 46560871)
245. S. Zhang: Beyond the Petri dish. Nat Biotech 22, 151-152(2004) (Pubitemid 38160524)
246. J. A. Hubbell: Materials as morphogenetic guides in tissue engineering. Current Opin Biotech 14, 551-558(2003) (Pubitemid 37298043)
247. L. Flynn, P. D. Dalton, M. S. Shoichet: Fiber templating of poly (2-hydroxyethyl methacrylate) for neural tissue engineering. Biomaterials 24, 4265-4272(2003) (Pubitemid 36809028)
248. T. Hadlock, C. Sundback, D. Hunter, M. Cheney, J. P. Vacanti: A polymer foam conduit seeded with Schwann cells promotes guided peripheral nerve regeneration. Tissue Engineering 6, 119-127(2000) (Pubitemid 30227168)
249. S. Blacher, V. Maquet, F. Schils, D. Martin, J. Schoenen, G. Moonen, R. Jérôme, J. P. Pirard: Image analysis of the axonal ingrowth into poly (D, L-lactide) porous scaffolds in relation to the 3-D porous structure. Biomaterials 24, 1033-1040(2003) (Pubitemid 36020391)
250. S. Stockols, M. H. Tuszynski: The fabrication and characterization of linearly oriented nerve guidance scaffolds for spinal cord injury. Biomaterials 25, 5839-5846(2004) (Pubitemid 38681168)
251. S. Stockols, M. Tuszynski: Freeze-dried agarose scaffolds with uniaxial channels stimulate and guide linear axonal growth following spinal cord injury. Biomaterials 27, 443-451(2006) (Pubitemid 41457247)
252. V. Maquet, D. Martin, B. Malgrange, R. Franzen, J. Schoenen, G. Moonen, R. Jérôme: Peripheral nerve regeneration using bioresorbable macroporous polylactide scaffolds. J Biomed Mater Res 52, 639-651(2000)
253. V. Maquet, D. Martin, F. Scholtes, R. Franzen, J. Schoenen, G. Moonen, R. Jérôme: Poly (D, L-lactide) foams modifed by poly (ethylene oxide)-block-poly (D, L-lactide) copolymers and a-FGF: in vitro and in vivo evaluation for spinal cord regeneration. Biomaterials 22, 1137-1146(2001) (Pubitemid 32229938)
254. A. Hurtado, L. Moon, V. Maquet, B. Blits, R. Jérôme, M. Oudega: Poly (D, L-lactic acid) macroporous guidance scaffolds seeded with Schwann cells genetically modifed to secrete a bi-functional neurotrophin implanted in the completely transected adult rat thoracic spinal cord. Biomaterials 27, 430-442(2006) (Pubitemid 41457246)
255. Y. D. Teng, E. B. Lavik, X. Qu, K. I. Park, J. Ourednik, D. Zurakowski, R. Langer, E. Y. Snyder: Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells. PNAS 99, 3024-3029(2002) (Pubitemid 34240579)
256. G. Mukhopadhyay, P. Doherty, F. S. Walsh, P. R. Crocker, M. T. Filbin: A novel role for myelin-associated glycoprotein as an inhibitor of axonal regeneration. Neuron 13, 757-767(1994) (Pubitemid 24300179)
257. Y. Luo, M. S. Shoichet: Light-activated immobilization of biomolecules to agarose hydrogels for controlled cellular response. Biomacromolecules 5, 2315-2323(2004) (Pubitemid 39585285)
258. J. M. Corey, B. C. Wheeler, G. J. Brewer: Compliance of hippocampal neurons to patterned substrate networks. J Neurosci Res 30, 300-307(1991)
259. D. Shaw, M. S. Shoichet: Towards spinal cord injury repair strategies: peptide surface modification of expanded poly (tetrafluoroethylene) fibers for guided neurite outgrowth in vitro. J Craniofacial Surg 14, 308-316(2003)
260. P. X. Ma, R. Zhang: Microtubular architecture of biodegradable polymer scaffolds. J Biomed Mater Res 56, 469-477(2001) (Pubitemid 32606007)