Quantitative analysis of cell signaling and drug action via mass spectrometry-based systems level phosphoproteomics

Proteomics

Volumn 9, Issue 6, 2009, Pages 1469-1487

  Tedford, Nathan C ^a,b   Hall, Amy B ^a   Graham, James R ^a   Murphy, Cheryl E ^a   Gordon, Neal F ^a   Radding, Jeffrey A ^a  

^a Epitome Biosystems   (United States)

^b Massachusetts Institute of Technology Cambridge   (United States)

Author keywords

Cell signaling; Drug development; Mass spectrometry; Phosphoproteomics; Systems biology

Indexed keywords

BIOLOGICAL MARKER; CELL ENZYME; ERLOTINIB; GEFITINIB; PHOSPHATASE; PHOSPHOPROTEIN; PHOSPHOTRANSFERASE; PHOSPHOTYROSINE;

CELL INTERACTION; DATA ANALYSIS; DRUG EFFECT; DRUG TARGETING; HUMAN; MASS SPECTROMETRY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PHOSPHORYLATION; PROTEOMICS; QUANTITATIVE ANALYSIS; REVIEW; SIGNAL TRANSDUCTION; TREATMENT RESPONSE;

ANIMALS; CELL LINE; DRUG DISCOVERY; HUMANS; MASS SPECTROMETRY; PHOSPHOPROTEINS; PROTEOMICS; SIGNAL TRANSDUCTION;

EID: 63049127416     PISSN: 16159853     EISSN: 16159861     Source Type: Journal    
DOI: 10.1002/pmic.200800468     Document Type: Review

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