Effects of HER2 overexpression on cell signaling networks governing proliferation and migration

Molecular Systems Biology

Volumn 2, Issue , 2006, Pages

  Wolf Yadlin, Alejandro ^a   Kumar, Neil ^b   Zhang, Yi ^a   Hautaniemi, Sampsa ^a,d   Zaman, Muhammad ^a   Kim, Hyung Do ^a   Grantcharova, Viara ^c   Lauffenburger, Douglas A ^a   White, Forest M ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b Massachusetts Institute of Technology Cambridge   (United States)

^c MERRIMACK PHARMACEUTICALS   (United States)

^d UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Cell migration; Cell proliferation; Epidermal growth factor receptor; Signal transduction; Tyrosine phosphorylation

Indexed keywords

EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR 2; NEU DIFFERENTIATION FACTOR; PHOSPHOTYROSINE; UNCLASSIFIED DRUG; EPIDERMAL GROWTH FACTOR RECEPTOR; HYBRID PROTEIN;

BREAST EPITHELIUM; CELL FUNCTION; CELL MIGRATION; CELL PROLIFERATION; CELL STIMULATION; DATA ANALYSIS; DIMERIZATION; GENE OVEREXPRESSION; HUMAN; MASS SPECTROMETRY; PARTIAL LEAST SQUARES REGRESSION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEOMICS; QUANTITATIVE ANALYSIS; REGULATORY MECHANISM; REVIEW; SELF ORGANIZING MAP ANALYSIS; SIGNAL TRANSDUCTION; TUMOR GROWTH; ALGORITHM; ARTICLE; BIOSYNTHESIS; BREAST; CELL DIVISION; CELL LINE; CELL MOTION; CHEMISTRY; COMPARATIVE STUDY; CYTOLOGY; DRUG EFFECT; EPITHELIUM CELL; FEMALE; GENE EXPRESSION; GENETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN PROCESSING; PROTO ONCOGENE; REGRESSION ANALYSIS; VALIDATION STUDY;

ALGORITHMS; BREAST; CELL DIVISION; CELL LINE; CELL MOVEMENT; DIMERIZATION; EPIDERMAL GROWTH FACTOR; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION; GENES, ERBB-1; GENES, ERBB-2; HUMANS; LEAST-SQUARES ANALYSIS; MASS SPECTROMETRY; NEUREGULIN-1; PHOSPHORYLATION; PHOSPHOTYROSINE; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, ERBB-2; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION;

EID: 33750696663     PISSN: 17444292     EISSN: 17444292     Source Type: Journal    
DOI: 10.1038/msb4100094     Document Type: Review

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