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Volumn 8, Issue 6, 2006, Pages 487-492

Challenges of drug discovery for personalized medicine

Author keywords

Biomarkers; Cytomics; Drug discovery; Nanobiotechnology; Personalized medicine; Pharmacogenetics; Pharmacogenomics; Pharmacometabolomics; Pharmacoproteomics; RNA interference

Indexed keywords

APOLIPOPROTEIN E; BETA 2 ADRENERGIC RECEPTOR; BIOLOGICAL MARKER; CANCER VACCINE; PARACETAMOL; VACCINE;

EID: 33845524213     PISSN: 14648431     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (24)

References (21)
  • 2
    • 13544270007 scopus 로고    scopus 로고
    • Disease-specific target selection: A critical first stop down the right road
    • Roses AD, Burns DK, Chissoe S, Middleton L, St Jean P: Disease-specific target selection: A critical first stop down the right road. Drug Disc Today (2005) 10(3):177-189.
    • (2005) Drug Disc Today , vol.10 , Issue.3 , pp. 177-189
    • Roses, A.D.1    Burns, D.K.2    Chissoe, S.3    Middleton, L.4    St Jean, P.5
  • 3
    • 18744369628 scopus 로고    scopus 로고
    • Pharmacogenomics and the drug discovery pipeline: When should it be implemented?
    • Penny MA, McHale D: Pharmacogenomics and the drug discovery pipeline: When should it be implemented? Am J Pharmacogenomics (2005) 6(1):53-62.
    • (2005) Am J Pharmacogenomics , vol.6 , Issue.1 , pp. 53-62
    • Penny, M.A.1    McHale, D.2
  • 4
    • 19444376971 scopus 로고    scopus 로고
    • Drug metabolism and variability among patients in drug response
    • Wilkinson GR: Drug metabolism and variability among patients in drug response. N Engl J Med (2005) 352(21):2211-2221.
    • (2005) N Engl J Med , vol.352 , Issue.21 , pp. 2211-2221
    • Wilkinson, G.R.1
  • 5
    • 0036649486 scopus 로고    scopus 로고
    • The role of proteomics in toxicology: Identification of biomarkers of toxicity by protein expression analysis
    • Kennedy S: The role of proteomics in toxicology: Identification of biomarkers of toxicity by protein expression analysis. Biomarkers (2002) 7(4):269-290.
    • (2002) Biomarkers , vol.7 , Issue.4 , pp. 269-290
    • Kennedy, S.1
  • 6
    • 16544379198 scopus 로고    scopus 로고
    • RNAI and sIRNA
    • Jain KK: RNAI and sIRNA. Pharmacogenomics (2004) 6(3):239-242.
    • (2004) Pharmacogenomics , vol.6 , Issue.3 , pp. 239-242
    • Jain, K.K.1
  • 8
    • 33646563442 scopus 로고    scopus 로고
    • Personalized medicine progresses
    • Haselden JN, Nicholls AW: Personalized medicine progresses. Nat Med (2008) 12(5):510-511.
    • (2008) Nat Med , vol.12 , Issue.5 , pp. 510-511
    • Haselden, J.N.1    Nicholls, A.W.2
  • 10
    • 23844456571 scopus 로고    scopus 로고
    • Cytomics, the human cytome project and systems biology. Top-down resolution of the molecular biocomplexity of organisms by single cell analysis
    • Valet G: Cytomics, the human cytome project and systems biology. Top-down resolution of the molecular biocomplexity of organisms by single cell analysis. Cell Prolif (2005) 38(4):171-174.
    • (2005) Cell Prolif , vol.38 , Issue.4 , pp. 171-174
    • Valet, G.1
  • 11
    • 33747781716 scopus 로고    scopus 로고
    • Cytomics as a new potential for drug discovery
    • Valet G: Cytomics as a new potential for drug discovery. Drug Disc Today (2008) 11(17-18):785-791.
    • (2008) Drug Disc Today , vol.11 , Issue.17-18 , pp. 785-791
    • Valet, G.1
  • 13
    • 26944462345 scopus 로고    scopus 로고
    • The role of nanobiotechnology in drug discovery
    • Jain KK: The role of nanobiotechnology in drug discovery. Drug Disc Today (2005) 10(21):1435-1442.
    • (2005) Drug Disc Today , vol.10 , Issue.21 , pp. 1435-1442
    • Jain, K.K.1
  • 14
    • 33745448269 scopus 로고    scopus 로고
    • The intricate side of systems biology
    • Volt E, Neves AR, Santos H: The intricate side of systems biology. Proc Natl Acad Sci USA (2008) 103(25):9452-9457.
    • (2008) Proc Natl Acad Sci USA , vol.103 , Issue.25 , pp. 9452-9457
    • Volt, E.1    Neves, A.R.2    Santos, H.3
  • 15
    • 20844432908 scopus 로고    scopus 로고
    • Can cell systems biology rescue drug discovery?
    • Butcher EC: Can cell systems biology rescue drug discovery? Nat Rev Drug Discov (2005) 4(6):461-467.
    • (2005) Nat Rev Drug Discov , vol.4 , Issue.6 , pp. 461-467
    • Butcher, E.C.1
  • 16
    • 23644448453 scopus 로고    scopus 로고
    • Personalised medicine for cancer: From drug development into clinical practice
    • Jain KK: Personalised medicine for cancer: From drug development into clinical practice. Exp Opin Pharmacother (2005) 6(9):1463-1476.
    • (2005) Exp Opin Pharmacother , vol.6 , Issue.9 , pp. 1463-1476
    • Jain, K.K.1
  • 17
    • 33748325671 scopus 로고    scopus 로고
    • Personalized peptide vaccines: A new therapeutic modality for cancer
    • Itoh K, Yamada A: Personalized peptide vaccines: A new therapeutic modality for cancer. Cancer Sci (2006) 97(10):970-976.
    • (2006) Cancer Sci , vol.97 , Issue.10 , pp. 970-976
    • Itoh, K.1    Yamada, A.2
  • 19
    • 13144251125 scopus 로고    scopus 로고
    • DNA methylation and cancer therapy: New developments and expectations
    • Esteller M: DNA methylation and cancer therapy: New developments and expectations. Curr Opin Oncol (2005) 17(1):55-60.
    • (2005) Curr Opin Oncol , vol.17 , Issue.1 , pp. 55-60
    • Esteller, M.1
  • 20
    • 17244374880 scopus 로고    scopus 로고
    • Role of oncoproteomics in the personalized management of cancer
    • Jain KK: Role of oncoproteomics in the personalized management of cancer. Expert Rev Proteomics (2004) 1(1):49-55.
    • (2004) Expert Rev Proteomics , vol.1 , Issue.1 , pp. 49-55
    • Jain, K.K.1
  • 21
    • 18244370796 scopus 로고    scopus 로고
    • How molecular profiling could revolutionize drug discovery
    • Stoughton RB, Friend SH: How molecular profiling could revolutionize drug discovery. Nat Rev Drug Discov (2005) 4(4):345-350.
    • (2005) Nat Rev Drug Discov , vol.4 , Issue.4 , pp. 345-350
    • Stoughton, R.B.1    Friend, S.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.