-
1
-
-
0141834466
-
Juvenile myelomonocytic leukemia
-
Jaffe E.S., Harris N.L., Stein H., and Vardimann J.W. (Eds), IARC Press, Lyon
-
Vardiman J.W., Pierre R., Imbert M., et al. Juvenile myelomonocytic leukemia. In: Jaffe E.S., Harris N.L., Stein H., and Vardimann J.W. (Eds). Pathology and genetics of tumours of haematopoietic and lymphoid tissues: World Health Organization Classification of Tumours (2001), IARC Press, Lyon 55-57
-
(2001)
Pathology and genetics of tumours of haematopoietic and lymphoid tissues: World Health Organization Classification of Tumours
, pp. 55-57
-
-
Vardiman, J.W.1
Pierre, R.2
Imbert, M.3
-
2
-
-
0026063878
-
Selective hypersensitivity to granulocyte-macrophage colony-stimulating factor by juvenile chronic myeloid leukemia hematopoietic progenitors
-
Emanuel P.D., Bates L.J., Castleberry R.P., Gualtieri R.J., and Zuckerman K.S. Selective hypersensitivity to granulocyte-macrophage colony-stimulating factor by juvenile chronic myeloid leukemia hematopoietic progenitors. Blood 77 (1991) 925-929
-
(1991)
Blood
, vol.77
, pp. 925-929
-
-
Emanuel, P.D.1
Bates, L.J.2
Castleberry, R.P.3
Gualtieri, R.J.4
Zuckerman, K.S.5
-
3
-
-
0031010989
-
Analysis of the coding sequence for the GM-CSF receptor alpha and beta chains in patients with juvenile chronic myeloid leukemia (JCML)
-
Freeburn R.W., Gale R.E., Wagner H.M., and Linch D.C. Analysis of the coding sequence for the GM-CSF receptor alpha and beta chains in patients with juvenile chronic myeloid leukemia (JCML). Exp Hematol 25 (1997) 306-311
-
(1997)
Exp Hematol
, vol.25
, pp. 306-311
-
-
Freeburn, R.W.1
Gale, R.E.2
Wagner, H.M.3
Linch, D.C.4
-
4
-
-
9044251606
-
Loss of NF1 results in activation of the Ras signaling pathway and leads to aberrant growth in haematopoietic cells
-
Bollag G., Clapp D.W., Shih S., et al. Loss of NF1 results in activation of the Ras signaling pathway and leads to aberrant growth in haematopoietic cells. Nat Genet 12 (1996) 144-148
-
(1996)
Nat Genet
, vol.12
, pp. 144-148
-
-
Bollag, G.1
Clapp, D.W.2
Shih, S.3
-
5
-
-
0347725620
-
Hyperactivation of protein kinase B and ERK have discrete effects on survival, proliferation, and cytokine expression in Nf1-deficient myeloid cells
-
Donovan S., See W., Bonifas J., Stokoe D., and Shannon K.M. Hyperactivation of protein kinase B and ERK have discrete effects on survival, proliferation, and cytokine expression in Nf1-deficient myeloid cells. Cancer Cell 2 (2002) 507-514
-
(2002)
Cancer Cell
, vol.2
, pp. 507-514
-
-
Donovan, S.1
See, W.2
Bonifas, J.3
Stokoe, D.4
Shannon, K.M.5
-
6
-
-
4544265186
-
Juvenile myelomonocytic leukemia
-
Emanuel P.D. Juvenile myelomonocytic leukemia. Curr Hematol Rep 3 (2004) 203-209
-
(2004)
Curr Hematol Rep
, vol.3
, pp. 203-209
-
-
Emanuel, P.D.1
-
7
-
-
33645280589
-
Inherited predispositions and hyperactive Ras in myeloid leukemogenesis
-
Lauchle J.O., Braun B.S., Loh M.L., and Shannon K. Inherited predispositions and hyperactive Ras in myeloid leukemogenesis. Pediatr Blood Cancer 46 (2006) 579-585
-
(2006)
Pediatr Blood Cancer
, vol.46
, pp. 579-585
-
-
Lauchle, J.O.1
Braun, B.S.2
Loh, M.L.3
Shannon, K.4
-
8
-
-
0030936323
-
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
-
Li J., Yen C., Liaw D., et al. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 275 (1997) 1943-1947
-
(1997)
Science
, vol.275
, pp. 1943-1947
-
-
Li, J.1
Yen, C.2
Liaw, D.3
-
9
-
-
17144436629
-
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
-
Steck P.A., Pershouse M.A., Jasser S.A., et al. Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nat Genet 15 (1997) 356-362
-
(1997)
Nat Genet
, vol.15
, pp. 356-362
-
-
Steck, P.A.1
Pershouse, M.A.2
Jasser, S.A.3
-
10
-
-
0031001041
-
TEP1 encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor beta
-
Li D.M., and Sun H. TEP1 encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor beta. Cancer Res 57 (1997) 2124-2129
-
(1997)
Cancer Res
, vol.57
, pp. 2124-2129
-
-
Li, D.M.1
Sun, H.2
-
11
-
-
4344684649
-
PTEN function: how normal cells control it and tumor cells lose it
-
Leslie N.R., and Downes C.P. PTEN function: how normal cells control it and tumor cells lose it. Biochem J 382 (2004) 1-11
-
(2004)
Biochem J
, vol.382
, pp. 1-11
-
-
Leslie, N.R.1
Downes, C.P.2
-
12
-
-
33745888913
-
PTEN function in normal and neoplastic growth
-
Chow L.M.L., and Baker S.J. PTEN function in normal and neoplastic growth. Cancer Lett 241 (2006) 184-196
-
(2006)
Cancer Lett
, vol.241
, pp. 184-196
-
-
Chow, L.M.L.1
Baker, S.J.2
-
13
-
-
33644513730
-
Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis
-
Cully M., You H., Levine A.J., and Mak T.W. Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis. Nat Rev 6 (2006) 184-192
-
(2006)
Nat Rev
, vol.6
, pp. 184-192
-
-
Cully, M.1
You, H.2
Levine, A.J.3
Mak, T.W.4
-
14
-
-
0025917376
-
Novel polyphosphoinositides in cell growth and activation
-
Auger K.R., and Cantley L.C. Novel polyphosphoinositides in cell growth and activation. Cancer Cells 3 (1991) 263-270
-
(1991)
Cancer Cells
, vol.3
, pp. 263-270
-
-
Auger, K.R.1
Cantley, L.C.2
-
15
-
-
0033551070
-
New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway
-
Cantley L.C., and Neel B.G. New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway. Proc Natl Acad Sci USA 96 (1999) 4240-4245
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 4240-4245
-
-
Cantley, L.C.1
Neel, B.G.2
-
16
-
-
0032583122
-
Tumor suppressor PTEN inhibits integrin- and growth factor-mediated mitogen-activated protein (MAP) kinase signaling pathways
-
Gu J., Tamura M., and Yamada K.M. Tumor suppressor PTEN inhibits integrin- and growth factor-mediated mitogen-activated protein (MAP) kinase signaling pathways. J Cell Biol 143 (1998) 1375-1383
-
(1998)
J Cell Biol
, vol.143
, pp. 1375-1383
-
-
Gu, J.1
Tamura, M.2
Yamada, K.M.3
-
17
-
-
0035869175
-
PTEN inhibits insulin-stimulated MEK/MAPK activation and cell growth by blocking IRS-1 phosphorylation and IRS-1/Grb-2/Sos complex formation in a breast cancer model
-
Weng L.P., Smith W.M., Brown J.L., and Eng C. PTEN inhibits insulin-stimulated MEK/MAPK activation and cell growth by blocking IRS-1 phosphorylation and IRS-1/Grb-2/Sos complex formation in a breast cancer model. Hum Mol Genet 10 (2001) 605-616
-
(2001)
Hum Mol Genet
, vol.10
, pp. 605-616
-
-
Weng, L.P.1
Smith, W.M.2
Brown, J.L.3
Eng, C.4
-
18
-
-
0038792224
-
Map kinase signaling pathways and hematologic malignancies
-
Platanias L.C. Map kinase signaling pathways and hematologic malignancies. Blood 101 (2003) 4667-4679
-
(2003)
Blood
, vol.101
, pp. 4667-4679
-
-
Platanias, L.C.1
-
19
-
-
0033606767
-
Shc and FAK differentially regulate cell motility and directionality modulated by PTEN
-
Gu J., Tamura M., Pankov R., et al. Shc and FAK differentially regulate cell motility and directionality modulated by PTEN. J Cell Biol 146 (1999) 389-403
-
(1999)
J Cell Biol
, vol.146
, pp. 389-403
-
-
Gu, J.1
Tamura, M.2
Pankov, R.3
-
20
-
-
0037205266
-
Parent CA. PI 3-Kinases and PTEN. How opposites chemoattract
-
Comer F.I. Parent CA. PI 3-Kinases and PTEN. How opposites chemoattract. Cell 109 (2002) 541-544
-
(2002)
Cell
, vol.109
, pp. 541-544
-
-
Comer, F.I.1
-
21
-
-
0031004088
-
Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome
-
Liaw D., Marsh D.J., Li J., et al. Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome. Nat Genet 16 (1997) 64-67
-
(1997)
Nat Genet
, vol.16
, pp. 64-67
-
-
Liaw, D.1
Marsh, D.J.2
Li, J.3
-
22
-
-
0031203265
-
Germline mutations in PTEN are present in Bannayan-Zonana Syndrome
-
Marsh D.J., Dahia P.L., Zheng Z., et al. Germline mutations in PTEN are present in Bannayan-Zonana Syndrome. Nat Genet 16 (1997) 333-334
-
(1997)
Nat Genet
, vol.16
, pp. 333-334
-
-
Marsh, D.J.1
Dahia, P.L.2
Zheng, Z.3
-
23
-
-
0036094196
-
Lack of PTEN expression in non-small cell lung cancer could be related to promoter methylation
-
Soria J.C., Lee H.Y., Lee J.I., et al. Lack of PTEN expression in non-small cell lung cancer could be related to promoter methylation. Clin Cancer Res 8 (2002) 1178-1184
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1178-1184
-
-
Soria, J.C.1
Lee, H.Y.2
Lee, J.I.3
-
24
-
-
0034976644
-
Frequent loss of PTEN expression is linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas
-
Kurose K., Zhou X.P., Araki T., Cannistra S.A., Maher E.R., and Eng C. Frequent loss of PTEN expression is linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas. Am J Pathol 158 (2001) 2097-2106
-
(2001)
Am J Pathol
, vol.158
, pp. 2097-2106
-
-
Kurose, K.1
Zhou, X.P.2
Araki, T.3
Cannistra, S.A.4
Maher, E.R.5
Eng, C.6
-
25
-
-
0030730905
-
Somatic deletions and mutations in the Cowden disease gene, PTEN, in sporadic thyroid tumors
-
Dahia P.L., Marsh D.J., Zheng Z., et al. Somatic deletions and mutations in the Cowden disease gene, PTEN, in sporadic thyroid tumors. Cancer Res 57 (1997) 4710-4713
-
(1997)
Cancer Res
, vol.57
, pp. 4710-4713
-
-
Dahia, P.L.1
Marsh, D.J.2
Zheng, Z.3
-
26
-
-
0033819340
-
Epigenetic PTEN silencing in malignant melanomas without PTEN mutation
-
Zhou X.P., Gimm O., Hampel H., Niemann T., Walker M.J., and Eng C. Epigenetic PTEN silencing in malignant melanomas without PTEN mutation. Am J Pathol 157 (2000) 1123-1128
-
(2000)
Am J Pathol
, vol.157
, pp. 1123-1128
-
-
Zhou, X.P.1
Gimm, O.2
Hampel, H.3
Niemann, T.4
Walker, M.J.5
Eng, C.6
-
27
-
-
0030761409
-
Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies
-
Tashiro H., Blazes M.S., Wu R., et al. Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies. Cancer Res 57 (1997) 3935-3940
-
(1997)
Cancer Res
, vol.57
, pp. 3935-3940
-
-
Tashiro, H.1
Blazes, M.S.2
Wu, R.3
-
28
-
-
0032898096
-
PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via multiple mechanisms in haematological malignancies
-
Dahia P.L., Aguiar R.C., Alberta J., et al. PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via multiple mechanisms in haematological malignancies. Hum Mol Genet 8 (1999) 185-193
-
(1999)
Hum Mol Genet
, vol.8
, pp. 185-193
-
-
Dahia, P.L.1
Aguiar, R.C.2
Alberta, J.3
-
29
-
-
0030799909
-
Somatic mutations of PTEN in glioblastoma multiforme
-
Wang S.I., Puc J., Li J., et al. Somatic mutations of PTEN in glioblastoma multiforme. Cancer Res 57 (1997) 4183-4186
-
(1997)
Cancer Res
, vol.57
, pp. 4183-4186
-
-
Wang, S.I.1
Puc, J.2
Li, J.3
-
30
-
-
33646351002
-
PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention
-
Zhang J., Grindley J.C., Yin T., et al. PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention. Nature 441 (2006) 518-522
-
(2006)
Nature
, vol.441
, pp. 518-522
-
-
Zhang, J.1
Grindley, J.C.2
Yin, T.3
-
31
-
-
0142099097
-
Differentiating juvenile myelomonocytic leukemia from infectious disease
-
Niemeyer C.M., Fenu S., Hasle H., et al. Differentiating juvenile myelomonocytic leukemia from infectious disease. Blood 91 (1998) 365-367
-
(1998)
Blood
, vol.91
, pp. 365-367
-
-
Niemeyer, C.M.1
Fenu, S.2
Hasle, H.3
-
32
-
-
0024284028
-
A simple salting out procedure for extracting DNA from human nucleated cells
-
Miller S.A., Dykes D.D., Polesky H.F., et al. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16 (1988) 1215-1216
-
(1988)
Nucleic Acids Res
, vol.16
, pp. 1215-1216
-
-
Miller, S.A.1
Dykes, D.D.2
Polesky, H.F.3
-
33
-
-
0029843950
-
Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands
-
Herman J.G., Graff J.R., Myohanen S., Nelkin B.D., and Baylin S.B. Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci USA 93 (1996) 9821-9826
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 9821-9826
-
-
Herman, J.G.1
Graff, J.R.2
Myohanen, S.3
Nelkin, B.D.4
Baylin, S.B.5
-
34
-
-
0032804575
-
Epigenetic mechanisms for progression of prostate cancer
-
Rennie P.S., and Nelson C.C. Epigenetic mechanisms for progression of prostate cancer. Cancer Metastasis Rev 17 (1998) 401-409
-
(1998)
Cancer Metastasis Rev
, vol.17
, pp. 401-409
-
-
Rennie, P.S.1
Nelson, C.C.2
-
35
-
-
0036316318
-
Hypermethylation of the p15(INK4B) gene in acute leukemia and myelodysplastic syndromes
-
Chen H., and Wu S. Hypermethylation of the p15(INK4B) gene in acute leukemia and myelodysplastic syndromes. Chin Med J (Engl) 115 (2002) 987-990
-
(2002)
Chin Med J (Engl)
, vol.115
, pp. 987-990
-
-
Chen, H.1
Wu, S.2
-
36
-
-
0038189509
-
Hypermethylation of GpG islands in the promoter region of p15(INK4b) in acute promyelocytic leukemia represses p15(INK4b) expression and correlates with poor prognosis
-
Teofili L., Martini M., Luongo M., et al. Hypermethylation of GpG islands in the promoter region of p15(INK4b) in acute promyelocytic leukemia represses p15(INK4b) expression and correlates with poor prognosis. Leukemia 17 (2003) 919-924
-
(2003)
Leukemia
, vol.17
, pp. 919-924
-
-
Teofili, L.1
Martini, M.2
Luongo, M.3
-
37
-
-
7144251865
-
A highly conserved processed PTEN pseudogene is located on chromosome band 9p21
-
Dahia P.L., FitzGerald M.G., Zhang X., et al. A highly conserved processed PTEN pseudogene is located on chromosome band 9p21. Oncogene 16 (1998) 2403-2406
-
(1998)
Oncogene
, vol.16
, pp. 2403-2406
-
-
Dahia, P.L.1
FitzGerald, M.G.2
Zhang, X.3
-
38
-
-
0034790016
-
mTOR, a novel target in breast cancer: the effect of CCI-779, an mTOR inhibitor, in preclinical models of breast cancer
-
Yu K., Toral-Barza L., Discafani C., et al. mTOR, a novel target in breast cancer: the effect of CCI-779, an mTOR inhibitor, in preclinical models of breast cancer. Endocrine-Related Cancer 8 (2001) 249-258
-
(2001)
Endocrine-Related Cancer
, vol.8
, pp. 249-258
-
-
Yu, K.1
Toral-Barza, L.2
Discafani, C.3
-
39
-
-
2342559981
-
The TOR pathway: a target for cancer therapy
-
Bjornsti, and Houghton. The TOR pathway: a target for cancer therapy. Nat Rev Cancer 4 (2004) 335-348
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 335-348
-
-
Bjornsti1
Houghton2
-
40
-
-
33646376411
-
Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells
-
Yilmaz O.H., Valdez R., Theisen B.K., et al. Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells. Nature 441 (2006) 475-482
-
(2006)
Nature
, vol.441
, pp. 475-482
-
-
Yilmaz, O.H.1
Valdez, R.2
Theisen, B.K.3
-
41
-
-
0033579163
-
Mutation spectra of PTEN/MMAC1 gene: a tumor suppressor with lipid phosphatase activity
-
Ali I.U., Schriml L.M., and Dean M. Mutation spectra of PTEN/MMAC1 gene: a tumor suppressor with lipid phosphatase activity. J Natl Cancer Inst 91 (1999) 1922-1932
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 1922-1932
-
-
Ali, I.U.1
Schriml, L.M.2
Dean, M.3
-
42
-
-
0042316755
-
PTEN: one gene, many syndromes
-
Eng C. PTEN: one gene, many syndromes. Hum Mutat 22 (2003) 183-198
-
(2003)
Hum Mutat
, vol.22
, pp. 183-198
-
-
Eng, C.1
-
43
-
-
0034854091
-
Regulation of PTEN transcription by p53
-
Stamblic V., MacPherson D., Sas D., et al. Regulation of PTEN transcription by p53. Mol Cell 8 (2001) 317-325
-
(2001)
Mol Cell
, vol.8
, pp. 317-325
-
-
Stamblic, V.1
MacPherson, D.2
Sas, D.3
-
44
-
-
2342481786
-
The tumour suppressor PTEN: involvement of a tumour suppressor candidate protein in PTEN turnover
-
Maehama J., O'Kahara F., and Kanaho Y. The tumour suppressor PTEN: involvement of a tumour suppressor candidate protein in PTEN turnover. Biochem Soc Trans 32 (2004) 343-347
-
(2004)
Biochem Soc Trans
, vol.32
, pp. 343-347
-
-
Maehama, J.1
O'Kahara, F.2
Kanaho, Y.3
-
45
-
-
0141955349
-
PTEN and p53: who will get the upper hand?
-
Trotman L.C., and Pandolfi P.P. PTEN and p53: who will get the upper hand?. Cancer Cell 3 (2003) 97-99
-
(2003)
Cancer Cell
, vol.3
, pp. 97-99
-
-
Trotman, L.C.1
Pandolfi, P.P.2
-
47
-
-
0035199914
-
The Egr-1 transcription factor directly activates PTEN during irradiation-induced signaling
-
Virolle T., Adamson E.D., Baron V., Birle D., Mercola D., Mustelin T., et al. The Egr-1 transcription factor directly activates PTEN during irradiation-induced signaling. Nat Cell Biol 3 (2001) 1124-1128
-
(2001)
Nat Cell Biol
, vol.3
, pp. 1124-1128
-
-
Virolle, T.1
Adamson, E.D.2
Baron, V.3
Birle, D.4
Mercola, D.5
Mustelin, T.6
-
48
-
-
33646185062
-
The tumor suppressor PTEN is necessary for human Sprouty 2-mediated inhibition of cell proliferation
-
Endersby R., Baker S.J., and Patel T.B. The tumor suppressor PTEN is necessary for human Sprouty 2-mediated inhibition of cell proliferation. J Biol Chem 281 (2006) 4816-4822
-
(2006)
J Biol Chem
, vol.281
, pp. 4816-4822
-
-
Endersby, R.1
Baker, S.J.2
Patel, T.B.3
-
49
-
-
0035873953
-
Tumor suppressor and anti-inflammatory actions of PPARγ agonists are mediated via upregulation of PTEN
-
Patel L., Pass I., Coxon P., Downes C.P., Smith S.A., and Macphee C.H. Tumor suppressor and anti-inflammatory actions of PPARγ agonists are mediated via upregulation of PTEN. Curr Biol 11 (2001) 764-768
-
(2001)
Curr Biol
, vol.11
, pp. 764-768
-
-
Patel, L.1
Pass, I.2
Coxon, P.3
Downes, C.P.4
Smith, S.A.5
Macphee, C.H.6
-
50
-
-
36148968456
-
RAS/ERK modulates TGFbeta-regulated PTEN expression in human pancreatic adenocarcinoma cells
-
Chow J.Y., Quach K.T., Cabrera B.L., Cabral J.A., Beck S.E., and Carethers J.M. RAS/ERK modulates TGFbeta-regulated PTEN expression in human pancreatic adenocarcinoma cells. Carcinogenesis 28 (2007) 2321-2327
-
(2007)
Carcinogenesis
, vol.28
, pp. 2321-2327
-
-
Chow, J.Y.1
Quach, K.T.2
Cabrera, B.L.3
Cabral, J.A.4
Beck, S.E.5
Carethers, J.M.6
-
51
-
-
20844435467
-
The NF1 tumor suppressor critically regulates TSC2 and mTOR
-
Johannessen C.M., Reczek E.E., James M.F., Brems H., Legius E., and Cichowski K. The NF1 tumor suppressor critically regulates TSC2 and mTOR. Proc Natl Acad Sci USA 102 (2005) 8573-8578
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 8573-8578
-
-
Johannessen, C.M.1
Reczek, E.E.2
James, M.F.3
Brems, H.4
Legius, E.5
Cichowski, K.6
-
52
-
-
0026006684
-
The role of monocyte-derived hemopoietic growth factors in the regulation of myeloproliferation in juvenile chronic myelogenous leukemia
-
Emanuel P.D., Bates L.J., Zhu S.W., Castleberry R.P., Gualtieri R.J., and Zuckerman K.S. The role of monocyte-derived hemopoietic growth factors in the regulation of myeloproliferation in juvenile chronic myelogenous leukemia. Exp Hematol 19 (1991) 1017-1024
-
(1991)
Exp Hematol
, vol.19
, pp. 1017-1024
-
-
Emanuel, P.D.1
Bates, L.J.2
Zhu, S.W.3
Castleberry, R.P.4
Gualtieri, R.J.5
Zuckerman, K.S.6
-
53
-
-
12144286410
-
Mutations in PTPN11 implicate the SHP-2 phosphatase in leukemogenesis
-
Loh M.L., Vattikuti S., Schubbert S., et al. Mutations in PTPN11 implicate the SHP-2 phosphatase in leukemogenesis. Blood 103 (2004) 2325-2331
-
(2004)
Blood
, vol.103
, pp. 2325-2331
-
-
Loh, M.L.1
Vattikuti, S.2
Schubbert, S.3
-
54
-
-
0033982718
-
Nf1 and Gmcsf interact in myeloid leukemogenesis
-
Birnbaum R.A., O'Marcaigh A., Wardak Z., et al. Nf1 and Gmcsf interact in myeloid leukemogenesis. Mol Cell 5 (2000) 189-195
-
(2000)
Mol Cell
, vol.5
, pp. 189-195
-
-
Birnbaum, R.A.1
O'Marcaigh, A.2
Wardak, Z.3
-
55
-
-
13844265841
-
Prognostic, therapeutic, and mechanistic implications of a mouse model of leukemia evoked by Shp2 (PTPN11) mutations
-
Mohi M.G., Williams I.R., Dearolf C.R., et al. Prognostic, therapeutic, and mechanistic implications of a mouse model of leukemia evoked by Shp2 (PTPN11) mutations. Cancer Cell 7 (2005) 179-191
-
(2005)
Cancer Cell
, vol.7
, pp. 179-191
-
-
Mohi, M.G.1
Williams, I.R.2
Dearolf, C.R.3
-
56
-
-
0035869212
-
PTEN coordinates G(1) arrest by down-regulating cyclin D1 via its protein phosphatase activity and up-regulating p27 via its lipid phosphatase activity in a breast cancer model
-
Weng L.P., Brown J.L., and Eng C. PTEN coordinates G(1) arrest by down-regulating cyclin D1 via its protein phosphatase activity and up-regulating p27 via its lipid phosphatase activity in a breast cancer model. Hum Mol Genet 10 (2001) 599-604
-
(2001)
Hum Mol Genet
, vol.10
, pp. 599-604
-
-
Weng, L.P.1
Brown, J.L.2
Eng, C.3
-
57
-
-
15944406764
-
PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth
-
Gao T., Furnari F., and Newton A.C. PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth. Mol Cell 18 (2005) 13-24
-
(2005)
Mol Cell
, vol.18
, pp. 13-24
-
-
Gao, T.1
Furnari, F.2
Newton, A.C.3
-
58
-
-
20444433205
-
C1-TEN is a negative regulator of the Akt/PKB signal transduction pathway and inhibits cell survival, proliferation, and migration
-
Hafizi S., Ibraimi F., and Dahlback B. C1-TEN is a negative regulator of the Akt/PKB signal transduction pathway and inhibits cell survival, proliferation, and migration. Faseb J 19 (2005) 971-973
-
(2005)
Faseb J
, vol.19
, pp. 971-973
-
-
Hafizi, S.1
Ibraimi, F.2
Dahlback, B.3
-
59
-
-
20144363954
-
Antileukemic activity of rapamycin in acute myeloid leukemia
-
Recher C., Beyne-Rauzy O., Demur C., et al. Antileukemic activity of rapamycin in acute myeloid leukemia. Blood 105 (2005) 2527-2534
-
(2005)
Blood
, vol.105
, pp. 2527-2534
-
-
Recher, C.1
Beyne-Rauzy, O.2
Demur, C.3
|