Hyperactivation of protein kinase B and ERK have discrete effects on survival, proliferation, and cytokine expression in Nf1-deficient myeloid cells

Cancer Cell

Volumn 2, Issue 6, 2002, Pages 507-514

  Donovan, Shane ^a   See, Wendy ^a   Bonifas, Jeannette ^a   Stokoe, David ^a,b   Shannon, Kevin M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; GROWTH FACTOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN C MYB; PROTEIN KINASE B; RAS PROTEIN; RETROVIRUS VECTOR; ENZYME INHIBITOR; NEUROFIBROMIN; ONCOPROTEIN; PROTEIN SERINE THREONINE KINASE;

ALLELE; ANIMAL CELL; APOPTOSIS; ARTICLE; BONE MARROW CELL; CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; FETUS; FETUS LIVER; GENE DELETION; GENETIC CODE; KNOCKOUT GENE; KNOCKOUT MOUSE; LIVER CELL; MOUSE; NEUROFIBROMATOSIS; NEUROFIBROMATOSIS TYPE 1 GENE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; TUMOR SUPPRESSOR GENE; UPREGULATION; WILD TYPE; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CELL DIVISION; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; GENETIC TRANSFECTION; METABOLISM; ONCOGENE MYB; ONCOGENE RAS; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; CELL DIVISION; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FETUS; GENES, MYB; GENES, RAS; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HEPATOCYTES; MITOGEN-ACTIVATED PROTEIN KINASES; MYELOID CELLS; NEUROFIBROMIN 1; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 0347725620     PISSN: 15356108     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1535-6108(02)00214-3     Document Type: Article

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