mTOR, a novel target in breast cancer: The effect of CCI-779, an mTOR inhibitor, in preclinical models of breast cancer

Endocrine-Related Cancer

Volumn 8, Issue 3, 2001, Pages 249-258

  Yu, K ^a   Toral Barza, L ^a   Discafani, C ^a   Zhang, W G ^a   Skotnicki, J ^a   Frost, P ^a   Gibbons, J J ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CELL PROTEIN; CYCLIN D; ESTROGEN; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; MYC PROTEIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; PROTEIN P27; RAPAMYCIN DERIVATIVE; TEMSIROLIMUS; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; BREAST CARCINOMA; CANCER CELL CULTURE; CANCER MODEL; CELL CYCLE G1 PHASE; CELL PROLIFERATION; CONFERENCE PAPER; CONTROLLED STUDY; DRUG SENSITIVITY; DRUG TARGETING; FEMALE; GENE OVEREXPRESSION; HORMONE DEPENDENCE; HUMAN; HUMAN CELL; IC 50; MOUSE; NONHUMAN; ONCOGENE NEU; PROTEIN EXPRESSION; TISSUE LEVEL;

ANIMALS; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; DRUG EVALUATION, PRECLINICAL; DRUG RESISTANCE, NEOPLASM; FEMALE; MICE; MICE, NUDE; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; SIROLIMUS; TUMOR CELLS, CULTURED;

EID: 0034790016     PISSN: 13510088     EISSN: None     Source Type: Journal    
DOI: 10.1677/erc.0.0080249     Document Type: Conference Paper

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