메뉴 건너뛰기




Volumn 9, Issue 3, 2009, Pages 206-216

The molecular programme of tumour reversion: The steps beyond malignant transformation

Author keywords

[No Author keywords available]

Indexed keywords

PRESENILIN 1; PROTEIN TSAP6; TRANSLATIONALLY CONTROLLED TUMOR PROTEIN; TUMOR PROTEIN; UNCLASSIFIED DRUG;

EID: 60749083173     PISSN: 1474175X     EISSN: 14741768     Source Type: Journal    
DOI: 10.1038/nrc2589     Document Type: Review
Times cited : (153)

References (153)
  • 2
    • 4043181214 scopus 로고    scopus 로고
    • Cancer genes and the pathways they control
    • Vogelstein, B. & Kinzler, K. W. Cancer genes and the pathways they control. Nature Med. 10, 789-799 (2004).
    • (2004) Nature Med , vol.10 , pp. 789-799
    • Vogelstein, B.1    Kinzler, K.W.2
  • 3
    • 0344018716 scopus 로고
    • Die Teratome nach ihrem Bau, ihrem Verlauf, ihrer Genese und im Vergleich zum experimentellen Teratoid.
    • Askanazy, M. Die Teratome nach ihrem Bau, ihrem Verlauf, ihrer Genese und im Vergleich zum experimentellen Teratoid. Verhandl. Deutsch. Pathol. 11, 39-82 (1907).
    • (1907) Verhandl. Deutsch. Pathol , vol.11 , pp. 39-82
    • Askanazy, M.1
  • 4
    • 37049230959 scopus 로고
    • Recovery of tumor cells from effects of the tumor-inducing principle in crown gall
    • Braun, A. C. Recovery of tumor cells from effects of the tumor-inducing principle in crown gall. Science 113, 651-653 (1951).
    • (1951) Science , vol.113 , pp. 651-653
    • Braun, A.C.1
  • 5
    • 0038224034 scopus 로고
    • A demonstration of the recovery of the crown-gall tumor cell with the use of complex tumors of single-cell origin
    • Braun, A. C. A demonstration of the recovery of the crown-gall tumor cell with the use of complex tumors of single-cell origin. Proc. Natl Acad. Sci. USA 45, 932-938 (1959).
    • (1959) Proc. Natl Acad. Sci. USA , vol.45 , pp. 932-938
    • Braun, A.C.1
  • 6
    • 33845867147 scopus 로고
    • The reversal of tumor growth
    • Braun, A. C. The reversal of tumor growth. Sci. Am. 213, 75-83 (1965).
    • (1965) Sci. Am , vol.213 , pp. 75-83
    • Braun, A.C.1
  • 7
    • 84965029816 scopus 로고
    • Testicular teratomas. I. Demonstration of teratogenesis by metamorphosis of multipotential cells
    • Pierce, G. B. & Dixon, F. J. Jr. Testicular teratomas. I. Demonstration of teratogenesis by metamorphosis of multipotential cells. Cancer 12, 573-583 (1959).
    • (1959) Cancer , vol.12 , pp. 573-583
    • Pierce, G.B.1    Dixon Jr., F.J.2
  • 8
    • 84883845299 scopus 로고
    • Multipotentiality of single embryonal carcinoma cells
    • Kleinsmith, L. J. & Pierce, G. B. Jr. Multipotentiality of single embryonal carcinoma cells. Cancer Res. 24, 1544-1551 (1964).
    • (1964) Cancer Res , vol.24 , pp. 1544-1551
    • Kleinsmith, L.J.1    Pierce Jr., G.B.2
  • 9
    • 0005922021 scopus 로고
    • Induction and differentiation of an epithelial tumour in the newt (Triturus cristatus)
    • Seilern-Aspang, F. & Kratochwil, K. Induction and differentiation of an epithelial tumour in the newt (Triturus cristatus). J. Embryol. Exp. Morphol. 10, 337-356 (1962).
    • (1962) J. Embryol. Exp. Morphol , vol.10 , pp. 337-356
    • Seilern-Aspang, F.1    Kratochwil, K.2
  • 10
    • 0002572411 scopus 로고
    • Reversion in hamster cells transformed by Rous sarcoma virus
    • Macpherson, I. Reversion in hamster cells transformed by Rous sarcoma virus. Science 148, 1731-1733 (1965).
    • (1965) Science , vol.148 , pp. 1731-1733
    • Macpherson, I.1
  • 11
    • 84914429508 scopus 로고
    • ed. Kirsten, W. H, Springer, Heidelberg
    • Ian McPherson. In Recent Results in Cancer Research Vol. 6 (ed. Kirsten, W. H.) 1-8 (Springer, Heidelberg, 1966).
    • (1966) Recent Results in Cancer Research , vol.6 , pp. 1-8
    • McPherson, I.1
  • 12
    • 0015491718 scopus 로고
    • Reversion of murine sarcoma virus transformed mouse cells: Variants without a rescuable sarcoma virus
    • Fischinger, P. J., Nomura, S., Peebles, P. T., Haapala, D. K. & Bassin, R. H. Reversion of murine sarcoma virus transformed mouse cells: variants without a rescuable sarcoma virus. Science 176, 1033-1035 (1972).
    • (1972) Science , vol.176 , pp. 1033-1035
    • Fischinger, P.J.1    Nomura, S.2    Peebles, P.T.3    Haapala, D.K.4    Bassin, R.H.5
  • 13
    • 0018663182 scopus 로고
    • Factors affecting phenotypic reversion of rat cells transformed by avian sarcoma virus
    • Wyke, J. A., Beamand, J. A. & Varmus, H. E. Factors affecting phenotypic reversion of rat cells transformed by avian sarcoma virus. Cold Spring Harb. Symp. Quant. Biol. 44 (Pt 2), 1065-1075 (1980).
    • (1980) Cold Spring Harb. Symp. Quant. Biol , vol.44 , Issue.PART 2 , pp. 1065-1075
    • Wyke, J.A.1    Beamand, J.A.2    Varmus, H.E.3
  • 14
    • 0029818753 scopus 로고    scopus 로고
    • Time-sensitive reversal of hyperplasia in transgenic mice expressing SV40 T antigen
    • Ewald, D. et al. Time-sensitive reversal of hyperplasia in transgenic mice expressing SV40 T antigen. Science 273, 1384-1386 (1996).
    • (1996) Science , vol.273 , pp. 1384-1386
    • Ewald, D.1
  • 15
    • 0033987718 scopus 로고    scopus 로고
    • Reversibility of acute B-cell leukaemia induced by BCR-ABL1
    • Huettner, C. S., Zhang, P., Van Etten, R. A. & Tenen, D. G. Reversibility of acute B-cell leukaemia induced by BCR-ABL1. Nature Genet. 24, 57-60 (2000).
    • (2000) Nature Genet , vol.24 , pp. 57-60
    • Huettner, C.S.1    Zhang, P.2    Van Etten, R.A.3    Tenen, D.G.4
  • 16
    • 0023752982 scopus 로고
    • Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia
    • Huang, M. E. et al. Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia. Blood 72, 567-572 (1988).
    • (1988) Blood , vol.72 , pp. 567-572
    • Huang, M.E.1
  • 17
    • 0025043959 scopus 로고
    • The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor α gene to a novel transcribed locus
    • de The, H., Chomienne, C., Lanotte, M., Degos, L. & Dejean, A. The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor α gene to a novel transcribed locus. Nature 347, 558-561 (1990).
    • (1990) Nature , vol.347 , pp. 558-561
    • de The, H.1    Chomienne, C.2    Lanotte, M.3    Degos, L.4    Dejean, A.5
  • 18
    • 0025223760 scopus 로고
    • Treatment of first relapse in acute promyelocytic leukaemia with all-trans retinoic acid
    • Degos, L. et al. Treatment of first relapse in acute promyelocytic leukaemia with all-trans retinoic acid. Lancet 336, 1440-1441 (1990).
    • (1990) Lancet , vol.336 , pp. 1440-1441
    • Degos, L.1
  • 19
    • 0027173862 scopus 로고    scopus 로고
    • Warrell, R. P. Jr, de The, H., Wang, Z. Y. & Degos, L. Acute promyelocytic leukemia. N. Engl. J. Med. 329, 177-189 (1993).
    • Warrell, R. P. Jr, de The, H., Wang, Z. Y. & Degos, L. Acute promyelocytic leukemia. N. Engl. J. Med. 329, 177-189 (1993).
  • 21
    • 0014290104 scopus 로고
    • Growth control in cultured cells: Selection of sublines with increased sensitivity to contact inhibition and decreased tumor-producing ability
    • Pollack, R. E., Green, H. & Todaro, G. J. Growth control in cultured cells: selection of sublines with increased sensitivity to contact inhibition and decreased tumor-producing ability. Proc. Natl Acad. Sci. USA 60, 126-133 (1968).
    • (1968) Proc. Natl Acad. Sci. USA , vol.60 , pp. 126-133
    • Pollack, R.E.1    Green, H.2    Todaro, G.J.3
  • 22
    • 0014426049 scopus 로고
    • Reversion of properties in cells transformed by polyoma virus
    • Rabinowitz, Z. & Sachs, L. Reversion of properties in cells transformed by polyoma virus. Nature 220, 1203-1206 (1968).
    • (1968) Nature , vol.220 , pp. 1203-1206
    • Rabinowitz, Z.1    Sachs, L.2
  • 23
    • 0018148864 scopus 로고
    • Control of normal cell differentiation and the phenotypic reversion of malignancy in myeloid leukaemia
    • Sachs, L. Control of normal cell differentiation and the phenotypic reversion of malignancy in myeloid leukaemia. Nature 274, 535-539 (1978).
    • (1978) Nature , vol.274 , pp. 535-539
    • Sachs, L.1
  • 24
    • 0036392034 scopus 로고    scopus 로고
    • Epigenetics wins over genetics: Induction of differentiation in tumor cells
    • Lotem, J. & Sachs, L. Epigenetics wins over genetics: induction of differentiation in tumor cells. Semin. Cancer Biol. 12, 339-346 (2002).
    • (2002) Semin. Cancer Biol , vol.12 , pp. 339-346
    • Lotem, J.1    Sachs, L.2
  • 25
    • 2342520813 scopus 로고
    • Detection of genes with a potential for suppressing the transformed phenotype associated with activated ras genes
    • Noda, M. et al. Detection of genes with a potential for suppressing the transformed phenotype associated with activated ras genes. Proc. Natl Acad. Sci. USA 86, 162-166 (1989).
    • (1989) Proc. Natl Acad. Sci. USA , vol.86 , pp. 162-166
    • Noda, M.1
  • 26
    • 0024600222 scopus 로고
    • A ras-related gene with transformation suppressor activity
    • Kitayama, H., Sugimoto, Y., Matsuzaki, T., Ikawa, Y. & Noda, M. A ras-related gene with transformation suppressor activity. Cell 56, 77-84 (1989).
    • (1989) Cell , vol.56 , pp. 77-84
    • Kitayama, H.1    Sugimoto, Y.2    Matsuzaki, T.3    Ikawa, Y.4    Noda, M.5
  • 27
    • 15044359236 scopus 로고    scopus 로고
    • Linking Rap to cell adhesion
    • Bos, J. L. Linking Rap to cell adhesion. Curr. Opin. Cell Biol. 17, 123-128 (2005).
    • (2005) Curr. Opin. Cell Biol , vol.17 , pp. 123-128
    • Bos, J.L.1
  • 28
    • 0016174481 scopus 로고
    • The effect of cells transferred into the mouse blastocyst on subsequent development
    • Brinster, R. L. The effect of cells transferred into the mouse blastocyst on subsequent development. J. Exp. Med. 140, 1049-1056 (1974).
    • (1974) J. Exp. Med , vol.140 , pp. 1049-1056
    • Brinster, R.L.1
  • 29
    • 0345366593 scopus 로고
    • Normal genetically mosaic mice produced from malignant teratocarcinoma cells
    • Mintz, B. & Illmensee, K. Normal genetically mosaic mice produced from malignant teratocarcinoma cells. Proc. Natl Acad. Sci. USA 72, 3585-3589 (1975).
    • (1975) Proc. Natl Acad. Sci. USA , vol.72 , pp. 3585-3589
    • Mintz, B.1    Illmensee, K.2
  • 30
    • 0020842771 scopus 로고
    • The cancer cell and its control by the embryo. Rous-Whipple Award lecture
    • Pierce, G. B. The cancer cell and its control by the embryo. Rous-Whipple Award lecture. Am. J. Pathol. 113, 117-124 (1983).
    • (1983) Am. J. Pathol , vol.113 , pp. 117-124
    • Pierce, G.B.1
  • 31
    • 12344318372 scopus 로고    scopus 로고
    • Context, tissue plasticity, and cancer: Are tumor stem cells also regulated by the microenvironment?
    • Bissell, M. J. & Labarge, M. A. Context, tissue plasticity, and cancer: are tumor stem cells also regulated by the microenvironment? Cancer Cell 7, 17-23 (2005).
    • (2005) Cancer Cell , vol.7 , pp. 17-23
    • Bissell, M.J.1    Labarge, M.A.2
  • 32
    • 0030936450 scopus 로고    scopus 로고
    • Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies
    • Weaver, V. M. et al. Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies. J. Cell Biol. 137, 231-245 (1997).
    • (1997) J. Cell Biol , vol.137 , pp. 231-245
    • Weaver, V.M.1
  • 33
    • 33947583623 scopus 로고    scopus 로고
    • Reprogramming metastatic tumour cells with embryonic microenvironments
    • Hendrix, M. J. et al. Reprogramming metastatic tumour cells with embryonic microenvironments. Nature Rev. Cancer 7, 246-255 (2007).
    • (2007) Nature Rev. Cancer , vol.7 , pp. 246-255
    • Hendrix, M.J.1
  • 34
    • 0027305113 scopus 로고
    • A model for tumor suppression using H-1 parvovirus
    • Telerman, A. et al. A model for tumor suppression using H-1 parvovirus. Proc. Natl Acad. Sci. USA 90, 8702-8706 (1993).
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 8702-8706
    • Telerman, A.1
  • 35
    • 36949056245 scopus 로고
    • Lack of oncogenic effect of the H-viruses for hamsters
    • Toolan, H. W. Lack of oncogenic effect of the H-viruses for hamsters. Nature 214, 1036 (1967).
    • (1967) Nature , vol.214 , pp. 1036
    • Toolan, H.W.1
  • 36
    • 0020393563 scopus 로고
    • Minute virus of mice inhibits cell transformation by simian virus 40
    • Mousset, S. & Rommelaere, J. Minute virus of mice inhibits cell transformation by simian virus 40. Nature 300, 537-539 (1982).
    • (1982) Nature , vol.300 , pp. 537-539
    • Mousset, S.1    Rommelaere, J.2
  • 37
    • 9444262440 scopus 로고    scopus 로고
    • Activation of the human homologue of the Drosophila sina gene in apoptosis and tumor suppression
    • Nemani, M. et al. Activation of the human homologue of the Drosophila sina gene in apoptosis and tumor suppression. Proc. Natl Acad. Sci. USA 93, 9039-9042 (1996).
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 9039-9042
    • Nemani, M.1
  • 38
    • 0037069412 scopus 로고    scopus 로고
    • Biological models and genes of tumor reversion: Cellular reprogramming through tpt1/TCTP and SIAH-1
    • Tuynder, M. et al. Biological models and genes of tumor reversion: cellular reprogramming through tpt1/TCTP and SIAH-1. Proc. Natl Acad. Sci. USA 99, 14976-14981 (2002).
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 14976-14981
    • Tuynder, M.1
  • 39
    • 7444246058 scopus 로고    scopus 로고
    • Translationally controlled tumor protein is a target of tumor reversion
    • Tuynder, M. et al. Translationally controlled tumor protein is a target of tumor reversion. Proc. Natl Acad. Sci. USA 101, 15364-15369 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 15364-15369
    • Tuynder, M.1
  • 40
    • 9244251506 scopus 로고    scopus 로고
    • Isolation of 10 differentially expressed cDNAs in p53-induced apoptosis: Activation of the vertebrate homologue of the drosophila seven in absentia gene
    • Amson, R. B. et al. Isolation of 10 differentially expressed cDNAs in p53-induced apoptosis: activation of the vertebrate homologue of the drosophila seven in absentia gene. Proc. Natl Acad. Sci. USA 93, 3953-3957 (1996).
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 3953-3957
    • Amson, R.B.1
  • 42
    • 0026674886 scopus 로고
    • Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction
    • Liang, P. & Pardee, A. B. Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. Science 257, 967-971 (1992).
    • (1992) Science , vol.257 , pp. 967-971
    • Liang, P.1    Pardee, A.B.2
  • 43
    • 12944293179 scopus 로고    scopus 로고
    • In vitro cloning of complex mixtures of DNA on microbeads: Physical separation of differentially expressed cDNAs
    • Brenner, S. et al. In vitro cloning of complex mixtures of DNA on microbeads: physical separation of differentially expressed cDNAs. Proc. Natl Acad. Sci. USA 97, 1665-1670 (2000).
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 1665-1670
    • Brenner, S.1
  • 44
    • 0034130561 scopus 로고    scopus 로고
    • Gene expression analysis by massively parallel signature sequencing (MPSS) on microbead arrays
    • Brenner, S. et al. Gene expression analysis by massively parallel signature sequencing (MPSS) on microbead arrays. Nature Biotechnol. 18, 630-634 (2000).
    • (2000) Nature Biotechnol , vol.18 , pp. 630-634
    • Brenner, S.1
  • 45
    • 0030802364 scopus 로고    scopus 로고
    • A novel p53-inducible gene, PAG608, encodes a nuclear zinc finger protein whose overexpression promotes apoptosis
    • Israeli, D. et al. A novel p53-inducible gene, PAG608, encodes a nuclear zinc finger protein whose overexpression promotes apoptosis. EMBO J. 16, 4384-4392 (1997).
    • (1997) EMBO J , vol.16 , pp. 4384-4392
    • Israeli, D.1
  • 46
    • 0025784539 scopus 로고
    • Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6
    • Yonish-Rouach, E. et al. Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6. Nature 352, 345-347 (1991).
    • (1991) Nature , vol.352 , pp. 345-347
    • Yonish-Rouach, E.1
  • 47
    • 0037418216 scopus 로고    scopus 로고
    • The p53-inducible TSAP6 gene product regulates apoptosis and the cell cycle and interacts with Nix and the Myt1 kinase
    • Passer, B. J. et al. The p53-inducible TSAP6 gene product regulates apoptosis and the cell cycle and interacts with Nix and the Myt1 kinase. Proc. Natl Acad. Sci. USA 100, 2284-2289 (2003).
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 2284-2289
    • Passer, B.J.1
  • 48
    • 0031593685 scopus 로고    scopus 로고
    • WAF-1 and results in apoptosis and tumor suppression
    • WAF-1 and results in apoptosis and tumor suppression. Nature Med. 4, 835-838 (1998).
    • (1998) Nature Med , vol.4 , pp. 835-838
    • Roperch, J.P.1
  • 49
    • 0027496935 scopus 로고
    • The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
    • Harper, J. W., Adami, G. R., Wei, N., Keyomarsi, K. & Elledge, S. J. The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75, 805-816 (1993).
    • (1993) Cell , vol.75 , pp. 805-816
    • Harper, J.W.1    Adami, G.R.2    Wei, N.3    Keyomarsi, K.4    Elledge, S.J.5
  • 50
    • 0027359827 scopus 로고
    • WAF1, a potential mediator of p53 tumor suppression
    • el-Deiry, W. S. et al. WAF1, a potential mediator of p53 tumor suppression. Cell 75, 817-825 (1993).
    • (1993) Cell , vol.75 , pp. 817-825
    • el-Deiry, W.S.1
  • 51
    • 0028236846 scopus 로고
    • Induction of WAF1/CIP1 by a p53-independent pathway
    • Michieli, P. et al. Induction of WAF1/CIP1 by a p53-independent pathway. Cancer Res. 54, 3391-3395 (1994).
    • (1994) Cancer Res , vol.54 , pp. 3391-3395
    • Michieli, P.1
  • 52
    • 0029103598 scopus 로고
    • p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage
    • Macleod, K. F. et al. p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage. Genes Dev. 9, 935-944 (1995).
    • (1995) Genes Dev , vol.9 , pp. 935-944
    • Macleod, K.F.1
  • 53
    • 0028986639 scopus 로고
    • Cip1 in muscle and other terminally differentiating cells
    • Cip1 in muscle and other terminally differentiating cells. Science 267, 1024-1027 (1995).
    • (1995) Science , vol.267 , pp. 1024-1027
    • Parker, S.B.1
  • 54
    • 0028941483 scopus 로고
    • Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD
    • Halevy, O. et al. Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD. Science 267, 1018-1021 (1995).
    • (1995) Science , vol.267 , pp. 1018-1021
    • Halevy, O.1
  • 55
    • 0032585634 scopus 로고    scopus 로고
    • WAF1/CIP1 transcription by RB binding proteins
    • WAF1/CIP1 transcription by RB binding proteins. Oncogene 17, 3463-3469 (1998).
    • (1998) Oncogene , vol.17 , pp. 3463-3469
    • Gartel, A.L.1
  • 56
    • 0030916486 scopus 로고    scopus 로고
    • Regulated ectopic expression of cyclin D1 induces transcriptional activation of the cdk inhibitor p21 gene without altering cell cycle progression
    • Hiyama, H., Iavarone, A., LaBaer, J. & Reeves, S. A. Regulated ectopic expression of cyclin D1 induces transcriptional activation of the cdk inhibitor p21 gene without altering cell cycle progression. Oncogene 14, 2533-2542 (1997).
    • (1997) Oncogene , vol.14 , pp. 2533-2542
    • Hiyama, H.1    Iavarone, A.2    LaBaer, J.3    Reeves, S.A.4
  • 57
    • 0032568323 scopus 로고    scopus 로고
    • Regulation of the cdk inhibitor p21 gene during cell cycle progression is under the control of the transcription factor E2F
    • Hiyama, H., Iavarone, A. & Reeves, S. A. Regulation of the cdk inhibitor p21 gene during cell cycle progression is under the control of the transcription factor E2F. Oncogene 16, 1513-1523 (1998).
    • (1998) Oncogene , vol.16 , pp. 1513-1523
    • Hiyama, H.1    Iavarone, A.2    Reeves, S.A.3
  • 58
    • 18244389734 scopus 로고    scopus 로고
    • KLF6, a candidate tumor suppressor gene mutated in prostate cancer
    • Narla, G. et al. KLF6, a candidate tumor suppressor gene mutated in prostate cancer. Science 294, 2563-2566 (2001).
    • (2001) Science , vol.294 , pp. 2563-2566
    • Narla, G.1
  • 60
    • 0347624593 scopus 로고    scopus 로고
    • Role for BRG1 in cell cycle control and tumor suppression
    • Hendricks, K. B., Shanahan, F. & Lees, E. Role for BRG1 in cell cycle control and tumor suppression. Mol. Cell. Biol. 24, 362-376 (2004).
    • (2004) Mol. Cell. Biol , vol.24 , pp. 362-376
    • Hendricks, K.B.1    Shanahan, F.2    Lees, E.3
  • 61
    • 17844384528 scopus 로고    scopus 로고
    • Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation
    • Rangarajan, A. et al. Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation. EMBO J. 20, 3427-3436 (2001).
    • (2001) EMBO J , vol.20 , pp. 3427-3436
    • Rangarajan, A.1
  • 62
    • 22344436360 scopus 로고    scopus 로고
    • WAF1/Cip1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation
    • WAF1/Cip1 is a negative transcriptional regulator of Wnt4 expression downstream of Notch1 activation. Genes Dev. 19, 1485-1495 (2005).
    • (2005) Genes Dev , vol.19 , pp. 1485-1495
    • Devgan, V.1    Mammucari, C.2    Millar, S.E.3    Brisken, C.4    Dotto, G.P.5
  • 63
    • 0032477603 scopus 로고    scopus 로고
    • WAF-1 reorganizes the nucleus in tumor suppression
    • WAF-1 reorganizes the nucleus in tumor suppression. Proc. Natl Acad. Sci. USA 95, 1131-1135 (1998).
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 1131-1135
    • Linares-Cruz, G.1
  • 64
    • 0025029382 scopus 로고
    • seven in absentia, a gene required for specification of R7 cell fate in the Drosophila eye
    • Carthew, R. W. & Rubin, G. M. seven in absentia, a gene required for specification of R7 cell fate in the Drosophila eye. Cell 63, 561-577 (1990).
    • (1990) Cell , vol.63 , pp. 561-577
    • Carthew, R.W.1    Rubin, G.M.2
  • 65
    • 0030827862 scopus 로고    scopus 로고
    • Mammalian homologs of seven in absentia regulate DCC via the ubiquitin-proteasome pathway
    • Hu, G. et al. Mammalian homologs of seven in absentia regulate DCC via the ubiquitin-proteasome pathway. Genes Dev. 11, 2701-2714 (1997).
    • (1997) Genes Dev , vol.11 , pp. 2701-2714
    • Hu, G.1
  • 66
    • 0030849728 scopus 로고    scopus 로고
    • PHYL acts to down-regulate TTK88, a transcriptional repressor of neuronal cell fates, by a SINA-dependent mechanism
    • Tang, A. H., Neufeld, T. P., Kwan, E. & Rubin, G. M. PHYL acts to down-regulate TTK88, a transcriptional repressor of neuronal cell fates, by a SINA-dependent mechanism. Cell 90, 459-467 (1997).
    • (1997) Cell , vol.90 , pp. 459-467
    • Tang, A.H.1    Neufeld, T.P.2    Kwan, E.3    Rubin, G.M.4
  • 67
    • 0030790796 scopus 로고    scopus 로고
    • Photoreceptor cell differentiation requires regulated proteolysis of the transcriptional repressor Tramtrack
    • Li, S., Li, Y., Carthew, R. W. & Lai, Z. C. Photoreceptor cell differentiation requires regulated proteolysis of the transcriptional repressor Tramtrack. Cell 90, 469-478 (1997).
    • (1997) Cell , vol.90 , pp. 469-478
    • Li, S.1    Li, Y.2    Carthew, R.W.3    Lai, Z.C.4
  • 68
    • 3042561857 scopus 로고    scopus 로고
    • Siah-1b is a direct transcriptional target of p53: Identification of the functional p53 responsive element in the siah-1b promoter
    • Fiucci, G. et al. Siah-1b is a direct transcriptional target of p53: identification of the functional p53 responsive element in the siah-1b promoter. Proc. Natl Acad. Sci. USA 101, 3510-3515 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 3510-3515
    • Fiucci, G.1
  • 69
    • 0037453020 scopus 로고    scopus 로고
    • A binding motif for Siah ubiquitin ligase
    • House, C. M. et al. A binding motif for Siah ubiquitin ligase. Proc. Natl Acad. Sci. USA 100, 3101-3106 (2003).
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 3101-3106
    • House, C.M.1
  • 70
    • 46449125390 scopus 로고    scopus 로고
    • Control of HIPK2 stability by ubiquitin ligase Siah-1 and checkpoint kinases ATM and ATR
    • Winter, M. et al. Control of HIPK2 stability by ubiquitin ligase Siah-1 and checkpoint kinases ATM and ATR. Nature Cell Biol. 10, 812-824 (2008).
    • (2008) Nature Cell Biol , vol.10 , pp. 812-824
    • Winter, M.1
  • 71
    • 2942731503 scopus 로고    scopus 로고
    • Siah2 regulates stability of prolyl-hydroxylases, controls HIF1α abundance, and modulates physiological responses to hypoxia
    • Nakayama, K. et al. Siah2 regulates stability of prolyl-hydroxylases, controls HIF1α abundance, and modulates physiological responses to hypoxia. Cell 117, 941-952 (2004).
    • (2004) Cell , vol.117 , pp. 941-952
    • Nakayama, K.1
  • 72
    • 0035947080 scopus 로고    scopus 로고
    • Siah-1, SIP, and Ebi collaborate in a novel pathway for β-catenin degradation linked to p53 responses
    • Matsuzawa, S. I. & Reed, J. C. Siah-1, SIP, and Ebi collaborate in a novel pathway for β-catenin degradation linked to p53 responses. Mol. Cell 7, 915-926 (2001).
    • (2001) Mol. Cell , vol.7 , pp. 915-926
    • Matsuzawa, S.I.1    Reed, J.C.2
  • 73
    • 0035947083 scopus 로고    scopus 로고
    • Siah-1 mediates a novel β-catenin degradation pathway linking p53 to the adenomatous polyposis coli protein
    • Liu, J. et al. Siah-1 mediates a novel β-catenin degradation pathway linking p53 to the adenomatous polyposis coli protein. Mol. Cell 7, 927-936 (2001).
    • (2001) Mol. Cell , vol.7 , pp. 927-936
    • Liu, J.1
  • 74
    • 0035909894 scopus 로고    scopus 로고
    • Siah-1 binds and regulates the function of Numb
    • Susini, L. et al. Siah-1 binds and regulates the function of Numb. Proc. Natl Acad. Sci. USA 98, 15067-15072 (2001).
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 15067-15072
    • Susini, L.1
  • 75
    • 0033617522 scopus 로고    scopus 로고
    • Notch signaling: Cell fate control and signal integration in development
    • Artavanis-Tsakonas, S., Rand, M. D. & Lake, R. J. Notch signaling: cell fate control and signal integration in development. Science 284, 770-776 (1999).
    • (1999) Science , vol.284 , pp. 770-776
    • Artavanis-Tsakonas, S.1    Rand, M.D.2    Lake, R.J.3
  • 76
    • 1242265691 scopus 로고    scopus 로고
    • Regulation of notch signaling activity
    • Schweisguth, F. Regulation of notch signaling activity. Curr. Biol. 14, R129-R138 (2004).
    • (2004) Curr. Biol , vol.14
    • Schweisguth, F.1
  • 77
    • 0024980213 scopus 로고
    • numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos
    • Uemura, T., Shepherd, S., Ackerman, L., Jan, L. Y. & Jan, Y. N. numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos. Cell 58, 349-360 (1989).
    • (1989) Cell , vol.58 , pp. 349-360
    • Uemura, T.1    Shepherd, S.2    Ackerman, L.3    Jan, L.Y.4    Jan, Y.N.5
  • 78
    • 0027947609 scopus 로고
    • Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells
    • Rhyu, M. S., Jan, L. Y. & Jan, Y. N. Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells. Cell 76, 477-491 (1994).
    • (1994) Cell , vol.76 , pp. 477-491
    • Rhyu, M.S.1    Jan, L.Y.2    Jan, Y.N.3
  • 79
    • 42449118549 scopus 로고    scopus 로고
    • Mechanisms of asymmetric cell division: Flies and worms pave the way
    • Gonczy, P. Mechanisms of asymmetric cell division: flies and worms pave the way. Nature Rev. Mol. Cell. Biol. 9, 355-366 (2008).
    • (2008) Nature Rev. Mol. Cell. Biol , vol.9 , pp. 355-366
    • Gonczy, P.1
  • 80
    • 3342938070 scopus 로고    scopus 로고
    • Continuing role for mouse Numb and Numbl in maintaining progenitor cells during cortical neurogenesis
    • Petersen, P. H., Zou, K., Krauss, S. & Zhong, W. Continuing role for mouse Numb and Numbl in maintaining progenitor cells during cortical neurogenesis. Nature Neurosci. 7, 803-811 (2004).
    • (2004) Nature Neurosci , vol.7 , pp. 803-811
    • Petersen, P.H.1    Zou, K.2    Krauss, S.3    Zhong, W.4
  • 81
    • 0029909203 scopus 로고    scopus 로고
    • The Drosophila Numb protein inhibits signaling of the Notch receptor during cell-cell interaction in sensory organ lineage
    • Frise, E., Knoblich, J. A., Younger-Shepherd, S., Jan, L. Y. & Jan, Y. N. The Drosophila Numb protein inhibits signaling of the Notch receptor during cell-cell interaction in sensory organ lineage. Proc. Natl Acad. Sci. USA 93, 11925-11932 (1996).
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 11925-11932
    • Frise, E.1    Knoblich, J.A.2    Younger-Shepherd, S.3    Jan, L.Y.4    Jan, Y.N.5
  • 82
    • 0030199973 scopus 로고    scopus 로고
    • Control of daughter cell fates during asymmetric division: Interaction of Numb and Notch
    • Guo, M., Jan, L. Y. & Jan, Y. N. Control of daughter cell fates during asymmetric division: interaction of Numb and Notch. Neuron 17, 27-41 (1996).
    • (1996) Neuron , vol.17 , pp. 27-41
    • Guo, M.1    Jan, L.Y.2    Jan, Y.N.3
  • 83
    • 0037663379 scopus 로고    scopus 로고
    • Mammalian numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain
    • McGill, M. A. & McGlade, C. J. Mammalian numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain. J. Biol. Chem. 278, 23196-23203 (2003).
    • (2003) J. Biol. Chem , vol.278 , pp. 23196-23203
    • McGill, M.A.1    McGlade, C.J.2
  • 84
    • 0030930853 scopus 로고    scopus 로고
    • Binding specificity and in vivo targets of the EH domain, a novel protein-protein interaction module
    • Salcini, A. E. et al. Binding specificity and in vivo targets of the EH domain, a novel protein-protein interaction module. Genes Dev. 11, 2239-2249 (1997).
    • (1997) Genes Dev , vol.11 , pp. 2239-2249
    • Salcini, A.E.1
  • 85
    • 0034638843 scopus 로고    scopus 로고
    • Numb is an endocytic protein
    • Santolini, E. et al. Numb is an endocytic protein. J. Cell Biol. 151, 1345-1352 (2000).
    • (2000) J. Cell Biol , vol.151 , pp. 1345-1352
    • Santolini, E.1
  • 86
    • 0036696444 scopus 로고    scopus 로고
    • The endocytic protein α-adaptin is required for numb-mediated asymmetric cell division in Drosophila
    • Berdnik, D., Torok, T., Gonzalez-Gaitan, M. & Knoblich, J. A. The endocytic protein α-adaptin is required for numb-mediated asymmetric cell division in Drosophila. Dev. Cell 3, 221-231 (2002).
    • (2002) Dev. Cell , vol.3 , pp. 221-231
    • Berdnik, D.1    Torok, T.2    Gonzalez-Gaitan, M.3    Knoblich, J.A.4
  • 87
    • 0025856717 scopus 로고
    • TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms
    • Ellisen, L. W. et al. TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell 66, 649-661 (1991).
    • (1991) Cell , vol.66 , pp. 649-661
    • Ellisen, L.W.1
  • 89
    • 0142259346 scopus 로고    scopus 로고
    • The role of Notch in tumorigenesis: Oncogene or tumour suppressor?
    • Radtke, F. & Raj, K. The role of Notch in tumorigenesis: oncogene or tumour suppressor? Nature Rev. Cancer 3, 756-767 (2003).
    • (2003) Nature Rev. Cancer , vol.3 , pp. 756-767
    • Radtke, F.1    Raj, K.2
  • 90
    • 38049046724 scopus 로고    scopus 로고
    • NUMB controls p53 tumour suppressor activity
    • Colaluca, I. N. et al. NUMB controls p53 tumour suppressor activity. Nature 451, 76-80 (2008).
    • (2008) Nature , vol.451 , pp. 76-80
    • Colaluca, I.N.1
  • 91
    • 9644283195 scopus 로고    scopus 로고
    • Inactivating mutations of the Siah-1 gene in gastric cancer
    • Kim, C. J. et al. Inactivating mutations of the Siah-1 gene in gastric cancer. Oncogene 23, 8591-8596 (2004).
    • (2004) Oncogene , vol.23 , pp. 8591-8596
    • Kim, C.J.1
  • 92
    • 27644561755 scopus 로고    scopus 로고
    • Hypoxia requires notch signaling to maintain the undifferentiated cell state
    • Gustafsson, M. V. et al. Hypoxia requires notch signaling to maintain the undifferentiated cell state. Dev. Cell 9, 617-628 (2005).
    • (2005) Dev. Cell , vol.9 , pp. 617-628
    • Gustafsson, M.V.1
  • 93
    • 33947217823 scopus 로고    scopus 로고
    • Interaction between β-catenin and HIF-1 promotes cellular adaptation to hypoxia
    • Kaidi, A., Williams, A. C. & Paraskeva, C. Interaction between β-catenin and HIF-1 promotes cellular adaptation to hypoxia. Nature Cell Biol. 9, 210-217 (2007).
    • (2007) Nature Cell Biol , vol.9 , pp. 210-217
    • Kaidi, A.1    Williams, A.C.2    Paraskeva, C.3
  • 94
    • 0029004341 scopus 로고
    • Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
    • Sherrington, R. et al. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature 375, 754-760 (1995).
    • (1995) Nature , vol.375 , pp. 754-760
    • Sherrington, R.1
  • 95
    • 0029101491 scopus 로고
    • Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene
    • Rogaev, E. I. et al. Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene. Nature 376, 775-778 (1995).
    • (1995) Nature , vol.376 , pp. 775-778
    • Rogaev, E.I.1
  • 96
    • 0029116848 scopus 로고
    • Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene
    • Levitan, D. & Greenwald, I. Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene. Nature 377, 351-354 (1995).
    • (1995) Nature , vol.377 , pp. 351-354
    • Levitan, D.1    Greenwald, I.2
  • 97
    • 35348860241 scopus 로고    scopus 로고
    • Presenilin: Running with scissors in the membrane
    • Selkoe, D. J. & Wolfe, M. S. Presenilin: running with scissors in the membrane. Cell 131, 215-221 (2007).
    • (2007) Cell , vol.131 , pp. 215-221
    • Selkoe, D.J.1    Wolfe, M.S.2
  • 98
    • 33745614108 scopus 로고    scopus 로고
    • The γ-secretase complex: Membrane-embedded proteolytic ensemble
    • Wolfe, M. S. The γ-secretase complex: membrane-embedded proteolytic ensemble. Biochemistry 45, 7931-7939 (2006).
    • (2006) Biochemistry , vol.45 , pp. 7931-7939
    • Wolfe, M.S.1
  • 99
    • 2542626705 scopus 로고    scopus 로고
    • Forebrain degeneration and ventricle enlargement caused by double knockout of Alzheimer's presenilin-1 and presenilin-2
    • Feng, R. et al. Forebrain degeneration and ventricle enlargement caused by double knockout of Alzheimer's presenilin-1 and presenilin-2. Proc. Natl Acad. Sci. USA 101, 8162-8167 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 8162-8167
    • Feng, R.1
  • 100
    • 0033168352 scopus 로고    scopus 로고
    • Mutant presenilin-1 induces apoptosis and downregulates Akt/PKB
    • Weihl, C. C. et al. Mutant presenilin-1 induces apoptosis and downregulates Akt/PKB. J. Neurosci. 19, 5360-5369 (1999).
    • (1999) J. Neurosci , vol.19 , pp. 5360-5369
    • Weihl, C.C.1
  • 101
    • 38349014705 scopus 로고    scopus 로고
    • Wild-type but not FAD mutant presenilin-1 prevents neuronal degeneration by promoting phosphatidylinositol 3-kinase neuroprotective signaling
    • Baki, L. et al. Wild-type but not FAD mutant presenilin-1 prevents neuronal degeneration by promoting phosphatidylinositol 3-kinase neuroprotective signaling. J. Neurosci. 28, 483-490 (2008).
    • (2008) J. Neurosci , vol.28 , pp. 483-490
    • Baki, L.1
  • 102
    • 0032539814 scopus 로고    scopus 로고
    • Calbindin D28k blocks the proapoptotic actions of mutant presenilin 1: Reduced oxidative stress and preserved mitochondrial function
    • Guo, Q., Christakos, S., Robinson, N. & Mattson, M. P. Calbindin D28k blocks the proapoptotic actions of mutant presenilin 1: reduced oxidative stress and preserved mitochondrial function. Proc. Natl Acad. Sci. USA 95, 3227-3232 (1998).
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 3227-3232
    • Guo, Q.1    Christakos, S.2    Robinson, N.3    Mattson, M.P.4
  • 103
    • 0032531793 scopus 로고    scopus 로고
    • Destabilization of β-catenin by mutations in presenilin-1 potentiates neuronal apoptosis
    • Zhang, Z. et al. Destabilization of β-catenin by mutations in presenilin-1 potentiates neuronal apoptosis. Nature 395, 698-702 (1998).
    • (1998) Nature , vol.395 , pp. 698-702
    • Zhang, Z.1
  • 104
    • 0037133649 scopus 로고    scopus 로고
    • Wild-type and mutated presenilins 2 trigger p53-dependent apoptosis and down-regulate presenilin 1 expression in HEK293 human cells and in murine neurons
    • Alves da Costa, C. et al. Wild-type and mutated presenilins 2 trigger p53-dependent apoptosis and down-regulate presenilin 1 expression in HEK293 human cells and in murine neurons. Proc. Natl Acad. Sci. USA 99, 4043-4048 (2002).
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 4043-4048
    • Alves da Costa, C.1
  • 105
    • 12944260632 scopus 로고    scopus 로고
    • Behavioral alterations associated with apoptosis and down-regulation of presenilin 1 in the brains of p53-deficient mice
    • Amson, R. et al. Behavioral alterations associated with apoptosis and down-regulation of presenilin 1 in the brains of p53-deficient mice. Proc. Natl Acad. Sci. USA 97, 5346-5350 (2000).
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 5346-5350
    • Amson, R.1
  • 106
    • 27644455133 scopus 로고    scopus 로고
    • Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells
    • Ohgami, R. S. et al. Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Nature Genet. 37, 1264-1269 (2005).
    • (2005) Nature Genet , vol.37 , pp. 1264-1269
    • Ohgami, R.S.1
  • 107
    • 8544232810 scopus 로고    scopus 로고
    • TSAP6 facilitates the secretion of translationally controlled tumor protein/histamine-releasing factor via a nonclassical pathway
    • Amzallag, N. et al. TSAP6 facilitates the secretion of translationally controlled tumor protein/histamine-releasing factor via a nonclassical pathway. J. Biol. Chem. 279, 46104-46112 (2004).
    • (2004) J. Biol. Chem , vol.279 , pp. 46104-46112
    • Amzallag, N.1
  • 108
    • 33646416463 scopus 로고    scopus 로고
    • The regulation of exosome secretion: A novel function of the p53 protein
    • Yu, X., Harris, S. L. & Levine, A. J. The regulation of exosome secretion: a novel function of the p53 protein. Cancer Res. 66, 4795-4801 (2006).
    • (2006) Cancer Res , vol.66 , pp. 4795-4801
    • Yu, X.1    Harris, S.L.2    Levine, A.J.3
  • 109
    • 0038701886 scopus 로고    scopus 로고
    • The mystery of nonclassical protein secretion. A current view on cargo proteins and potential export routes
    • Nickel, W. The mystery of nonclassical protein secretion. A current view on cargo proteins and potential export routes. Eur. J. Biochem. 270, 2109-2119 (2003).
    • (2003) Eur. J. Biochem , vol.270 , pp. 2109-2119
    • Nickel, W.1
  • 110
    • 0036676445 scopus 로고    scopus 로고
    • Exosomes: Composition, biogenesis and function
    • Thery, C., Zitvogel, L. & Amigorena, S. Exosomes: composition, biogenesis and function. Nature Rev. Immunol. 2, 569-579 (2002).
    • (2002) Nature Rev. Immunol , vol.2 , pp. 569-579
    • Thery, C.1    Zitvogel, L.2    Amigorena, S.3
  • 111
    • 0029989258 scopus 로고    scopus 로고
    • B lymphocytes secrete antigen-presenting vesicles
    • Raposo, G. et al. B lymphocytes secrete antigen-presenting vesicles. J. Exp. Med. 183, 1161-1172 (1996).
    • (1996) J. Exp. Med , vol.183 , pp. 1161-1172
    • Raposo, G.1
  • 113
    • 0031863853 scopus 로고    scopus 로고
    • Eradication of established murine tumors using a novel cell-free vaccine: Dendritic cell-derived exosomes
    • Zitvogel, L. et al. Eradication of established murine tumors using a novel cell-free vaccine: dendritic cell-derived exosomes. Nature Med. 4, 594-600 (1998).
    • (1998) Nature Med , vol.4 , pp. 594-600
    • Zitvogel, L.1
  • 114
    • 54049088501 scopus 로고    scopus 로고
    • Exosome secretion, including the DNA damage-induced p53-dependent secretory pathway, is severely compromised in TSAP6/Steap3-null mice
    • Lespagnol, A. et al. Exosome secretion, including the DNA damage-induced p53-dependent secretory pathway, is severely compromised in TSAP6/Steap3-null mice. Cell Death Differ. 15, 1723-1733 (2008).
    • (2008) Cell Death Differ , vol.15 , pp. 1723-1733
    • Lespagnol, A.1
  • 115
    • 0019817630 scopus 로고
    • Transcriptional and translational control of cytoplasmic proteins after serum stimulation of quiescent Swiss 3T3 cells
    • Thomas, G., Thomas, G. & Luther, H. Transcriptional and translational control of cytoplasmic proteins after serum stimulation of quiescent Swiss 3T3 cells. Proc. Natl Acad. Sci. USA 78, 5712-5716 (1981).
    • (1981) Proc. Natl Acad. Sci. USA , vol.78 , pp. 5712-5716
    • Thomas, G.1    Thomas, G.2    Luther, H.3
  • 116
    • 0020366075 scopus 로고
    • Messenger RNA species partially in a repressed state in mouse sarcoma ascites cells
    • Yenofsky, R., Bergmann, I. & Brawerman, G. Messenger RNA species partially in a repressed state in mouse sarcoma ascites cells. Proc. Natl Acad. Sci. USA 79, 5876-5880 (1982).
    • (1982) Proc. Natl Acad. Sci. USA , vol.79 , pp. 5876-5880
    • Yenofsky, R.1    Bergmann, I.2    Brawerman, G.3
  • 117
    • 0028982775 scopus 로고
    • Molecular identification of an IgE-dependent histamine-releasing factor
    • MacDonald, S. M., Rafnar, T., Langdon, J. & Lichtenstein, L. M. Molecular identification of an IgE-dependent histamine-releasing factor. Science 269, 688-690 (1995).
    • (1995) Science , vol.269 , pp. 688-690
    • MacDonald, S.M.1    Rafnar, T.2    Langdon, J.3    Lichtenstein, L.M.4
  • 118
    • 0028652397 scopus 로고
    • Translational regulation of the mammalian growth-related protein P23: Involvement of eIF-4E
    • Bommer, U. A. et al. Translational regulation of the mammalian growth-related protein P23: involvement of eIF-4E. Cell. Mol. Biol. Res. 40, 633-641 (1994).
    • (1994) Cell. Mol. Biol. Res , vol.40 , pp. 633-641
    • Bommer, U.A.1
  • 119
    • 0031423822 scopus 로고    scopus 로고
    • Two-dimensional electrophoretic separation of yeast proteins using a non-linear wide range (pH 3-10) immobilized pH gradient in the first dimension; reproducibility and evidence for isoelectric focusing of alkaline (pI > 7) proteins
    • Norbeck, J. & Blomberg, A. Two-dimensional electrophoretic separation of yeast proteins using a non-linear wide range (pH 3-10) immobilized pH gradient in the first dimension; reproducibility and evidence for isoelectric focusing of alkaline (pI > 7) proteins. Yeast 13, 1519-1534 (1997).
    • (1997) Yeast , vol.13 , pp. 1519-1534
    • Norbeck, J.1    Blomberg, A.2
  • 120
    • 0035861647 scopus 로고    scopus 로고
    • Characterization of fortilin, a novel antiapoptotic protein
    • Li, F., Zhang, D. & Fujise, K. Characterization of fortilin, a novel antiapoptotic protein. J. Biol. Chem. 276, 47542-47549 (2001).
    • (2001) J. Biol. Chem , vol.276 , pp. 47542-47549
    • Li, F.1    Zhang, D.2    Fujise, K.3
  • 121
    • 16244384614 scopus 로고    scopus 로고
    • Stabilization and enhancement of the antiapoptotic activity of mcl-1 by TCTP
    • Liu, H., Peng, H. W., Cheng, Y. S., Yuan, H. S. & Yang-Yen, H. F. Stabilization and enhancement of the antiapoptotic activity of mcl-1 by TCTP. Mol. Cell. Biol. 25, 3117-3126 (2005).
    • (2005) Mol. Cell. Biol , vol.25 , pp. 3117-3126
    • Liu, H.1    Peng, H.W.2    Cheng, Y.S.3    Yuan, H.S.4    Yang-Yen, H.F.5
  • 122
    • 23044467160 scopus 로고    scopus 로고
    • An N-terminal region of translationally controlled tumor protein is required for its antiapoptotic activity
    • Yang, Y. et al. An N-terminal region of translationally controlled tumor protein is required for its antiapoptotic activity. Oncogene 24, 4778-4788 (2005).
    • (2005) Oncogene , vol.24 , pp. 4778-4788
    • Yang, Y.1
  • 123
    • 47249118484 scopus 로고    scopus 로고
    • TCTP protects from apoptotic cell death by antagonizing bax function
    • Susini, L. et al. TCTP protects from apoptotic cell death by antagonizing bax function. Cell Death Differ. 15, 1211-1220 (2008).
    • (2008) Cell Death Differ , vol.15 , pp. 1211-1220
    • Susini, L.1
  • 124
    • 33746214722 scopus 로고    scopus 로고
    • Translationally controlled tumor protein from Madurella mycetomatis, a marker for tumorous mycetoma progression
    • van de Sande, W. W. et al. Translationally controlled tumor protein from Madurella mycetomatis, a marker for tumorous mycetoma progression. J. Immunol. 177, 1997-2005 (2006).
    • (2006) J. Immunol , vol.177 , pp. 1997-2005
    • van de Sande, W.W.1
  • 125
    • 0343337581 scopus 로고    scopus 로고
    • Molecular identification of IgE-dependent histamine-releasing factor as a B cell growth factor
    • Kang, H. S. et al. Molecular identification of IgE-dependent histamine-releasing factor as a B cell growth factor. J. Immunol. 166, 6545-6554 (2001).
    • (2001) J. Immunol , vol.166 , pp. 6545-6554
    • Kang, H.S.1
  • 126
    • 49149109033 scopus 로고    scopus 로고
    • Microarray analysis of perichondral and reserve growth plate zones identifies differential gene expressions and signal pathways
    • Zhang, M., Pritchard, M. R., Middleton, F. A., Horton, J. A. & Damron, T. A. Microarray analysis of perichondral and reserve growth plate zones identifies differential gene expressions and signal pathways. Bone 43, 511-520 (2008).
    • (2008) Bone , vol.43 , pp. 511-520
    • Zhang, M.1    Pritchard, M.R.2    Middleton, F.A.3    Horton, J.A.4    Damron, T.A.5
  • 127
    • 0035794065 scopus 로고    scopus 로고
    • Decreased brain histamine-releasing factor protein in patients with Down syndrome and Alzheimer's disease
    • Kim, S. H., Cairns, N., Fountoulakisc, M. & Lubec, G. Decreased brain histamine-releasing factor protein in patients with Down syndrome and Alzheimer's disease. Neurosci. Lett. 300, 41-44 (2001).
    • (2001) Neurosci. Lett , vol.300 , pp. 41-44
    • Kim, S.H.1    Cairns, N.2    Fountoulakisc, M.3    Lubec, G.4
  • 128
    • 0032892605 scopus 로고    scopus 로고
    • The growth-related, translationally controlled protein P23 has properties of a tubulin binding protein and associates transiently with microtubules during the cell cycle
    • Gachet, Y. et al. The growth-related, translationally controlled protein P23 has properties of a tubulin binding protein and associates transiently with microtubules during the cell cycle. J. Cell Sci. 112 (Pt 8), 1257-1271 (1999).
    • (1999) J. Cell Sci , vol.112 , Issue.PART 8 , pp. 1257-1271
    • Gachet, Y.1
  • 129
    • 52149123920 scopus 로고    scopus 로고
    • Chfr interacts and colocalizes with TCTP to the mitotic spindle
    • 26 May, doi:10.1038/onc.2008.167
    • Burgess, A. et al. Chfr interacts and colocalizes with TCTP to the mitotic spindle. Oncogene 26 May 2008 (doi:10.1038/onc.2008.167).
    • (2008) Oncogene
    • Burgess, A.1
  • 130
    • 10744220545 scopus 로고    scopus 로고
    • Translationally controlled tumor protein acts as a guanine nucleotide dissociation inhibitor on the translation elongation factor eEF1A
    • Cans, C. et al. Translationally controlled tumor protein acts as a guanine nucleotide dissociation inhibitor on the translation elongation factor eEF1A. Proc. Natl Acad. Sci. USA 100, 13892-13897 (2003).
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 13892-13897
    • Cans, C.1
  • 131
    • 34249021056 scopus 로고    scopus 로고
    • The expression of AmphiTCTP, a TCTP orthologous gene in amphioxus related to the development of notochord and somites
    • Chen, Z. et al. The expression of AmphiTCTP, a TCTP orthologous gene in amphioxus related to the development of notochord and somites. Comp. Biochem. Physiol. B Biochem. Mol. Biol. 147, 460-465 (2007).
    • (2007) Comp. Biochem. Physiol. B Biochem. Mol. Biol , vol.147 , pp. 460-465
    • Chen, Z.1
  • 132
    • 41649107549 scopus 로고    scopus 로고
    • Temporal regulation of embryonic M-phases
    • Kubiak, J. Z. et al. Temporal regulation of embryonic M-phases. Folia Histochem. Cytobiol. 46, 5-9 (2008).
    • (2008) Folia Histochem. Cytobiol , vol.46 , pp. 5-9
    • Kubiak, J.Z.1
  • 133
    • 34247388883 scopus 로고    scopus 로고
    • Tpt1 activates transcription of oct4 and nanog in transplanted somatic nuclei
    • Koziol, M. J., Garrett, N. & Gurdon, J. B. Tpt1 activates transcription of oct4 and nanog in transplanted somatic nuclei. Curr. Biol. 17, 801-807 (2007).
    • (2007) Curr. Biol , vol.17 , pp. 801-807
    • Koziol, M.J.1    Garrett, N.2    Gurdon, J.B.3
  • 134
    • 34347393912 scopus 로고    scopus 로고
    • Bovine oocytes with the potential to reprogram somatic cell nuclei have a unique 23-kDa protein, phosphorylated transcriptionally controlled tumor protein (TCTP)
    • Tani, T., Shimada, H., Kato, Y. & Tsunoda, Y. Bovine oocytes with the potential to reprogram somatic cell nuclei have a unique 23-kDa protein, phosphorylated transcriptionally controlled tumor protein (TCTP). Cloning Stem Cells 9, 267-280 (2007).
    • (2007) Cloning Stem Cells , vol.9 , pp. 267-280
    • Tani, T.1    Shimada, H.2    Kato, Y.3    Tsunoda, Y.4
  • 135
    • 33847174115 scopus 로고    scopus 로고
    • Drosophila TCTP is essential for growth and proliferation through regulation of dRheb GTPase
    • Hsu, Y. C., Chern, J. J., Cai, Y., Liu, M. & Choi, K. W. Drosophila TCTP is essential for growth and proliferation through regulation of dRheb GTPase. Nature 445, 785-788 (2007).
    • (2007) Nature , vol.445 , pp. 785-788
    • Hsu, Y.C.1    Chern, J.J.2    Cai, Y.3    Liu, M.4    Choi, K.W.5
  • 136
    • 34347391544 scopus 로고    scopus 로고
    • A knockout mouse approach reveals that TCTP functions as an essential factor for cell proliferation and survival in a tissue- or cell type-specific manner
    • Chen, S. H. et al. A knockout mouse approach reveals that TCTP functions as an essential factor for cell proliferation and survival in a tissue- or cell type-specific manner. Mol. Biol. Cell 18, 2525-2532 (2007).
    • (2007) Mol. Biol. Cell , vol.18 , pp. 2525-2532
    • Chen, S.H.1
  • 137
    • 0037686329 scopus 로고    scopus 로고
    • Genomic organization and expression of mouse Tpt1 gene
    • Fiucci, G. et al. Genomic organization and expression of mouse Tpt1 gene. Genomics 81, 570-578 (2003).
    • (2003) Genomics , vol.81 , pp. 570-578
    • Fiucci, G.1
  • 138
    • 0344063368 scopus 로고    scopus 로고
    • Oct-3/4 is a dose-dependent oncogenic fate determinant
    • Gidekel, S., Pizov, G., Bergman, Y. & Pikarsky, E. Oct-3/4 is a dose-dependent oncogenic fate determinant. Cancer Cell 4, 361-370 (2003).
    • (2003) Cancer Cell , vol.4 , pp. 361-370
    • Gidekel, S.1    Pizov, G.2    Bergman, Y.3    Pikarsky, E.4
  • 139
    • 18844392836 scopus 로고    scopus 로고
    • Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues
    • Hochedlinger, K., Yamada, Y., Beard, C. & Jaenisch, R. Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues. Cell 121, 465-477 (2005).
    • (2005) Cell , vol.121 , pp. 465-477
    • Hochedlinger, K.1    Yamada, Y.2    Beard, C.3    Jaenisch, R.4
  • 140
    • 27144512725 scopus 로고    scopus 로고
    • Gamma secretase inhibitor blocks Notch activation and induces apoptosis in Kaposi's sarcoma tumor cells
    • Curry, C. L. et al. Gamma secretase inhibitor blocks Notch activation and induces apoptosis in Kaposi's sarcoma tumor cells. Oncogene 24, 6333-6344 (2005).
    • (2005) Oncogene , vol.24 , pp. 6333-6344
    • Curry, C.L.1
  • 141
    • 30444436343 scopus 로고    scopus 로고
    • Activating Notch1 mutations in mouse models of T-ALL
    • O'Neil, J. et al. Activating Notch1 mutations in mouse models of T-ALL. Blood 107, 781-785 (2006).
    • (2006) Blood , vol.107 , pp. 781-785
    • O'Neil, J.1
  • 142
    • 20544460148 scopus 로고    scopus 로고
    • Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells
    • van Es, J. H. et al. Notch/γ-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells. Nature 435, 959-963 (2005).
    • (2005) Nature , vol.435 , pp. 959-963
    • van Es, J.H.1
  • 143
    • 4444303958 scopus 로고    scopus 로고
    • p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas
    • Qin, J. Z. et al. p53-independent NOXA induction overcomes apoptotic resistance of malignant melanomas. Mol. Cancer Ther. 3, 895-902 (2004).
    • (2004) Mol. Cancer Ther , vol.3 , pp. 895-902
    • Qin, J.Z.1
  • 144
    • 0029986996 scopus 로고    scopus 로고
    • Detection of apoptosis in KG-1a leukemic cells treated with investigational drugs
    • Efferth, T. et al. Detection of apoptosis in KG-1a leukemic cells treated with investigational drugs. Arzneimittelforschung 46, 196-200 (1996).
    • (1996) Arzneimittelforschung , vol.46 , pp. 196-200
    • Efferth, T.1
  • 145
    • 0030893422 scopus 로고    scopus 로고
    • Stereochemistry-dependent cytotoxicity of some artemisinin derivatives
    • Beekman, A. C. et al. Stereochemistry-dependent cytotoxicity of some artemisinin derivatives. J. Nat. Prod. 60, 325-330 (1997).
    • (1997) J. Nat. Prod , vol.60 , pp. 325-330
    • Beekman, A.C.1
  • 146
    • 0032568952 scopus 로고    scopus 로고
    • The Plasmodium falciparum translationally controlled tumor protein homolog and its reaction with the antimalarial drug artemisinin
    • Bhisutthibhan, J. et al. The Plasmodium falciparum translationally controlled tumor protein homolog and its reaction with the antimalarial drug artemisinin. J. Biol. Chem. 273, 16192-16198 (1998).
    • (1998) J. Biol. Chem , vol.273 , pp. 16192-16198
    • Bhisutthibhan, J.1
  • 147
    • 0001313691 scopus 로고
    • A Reversion to wild-type associated with crossing-over in Drosophila melanogaster
    • Oliver, C. P. A Reversion to wild-type associated with crossing-over in Drosophila melanogaster. Proc. Natl Acad. Sci. USA 26, 452-454 (1940).
    • (1940) Proc. Natl Acad. Sci. USA , vol.26 , pp. 452-454
    • Oliver, C.P.1
  • 148
    • 0027181631 scopus 로고
    • Mechanisms of reversion
    • Noda, M. Mechanisms of reversion. FASEB J. 7, 834-840 (1993).
    • (1993) FASEB J , vol.7 , pp. 834-840
    • Noda, M.1
  • 149
    • 4644344326 scopus 로고    scopus 로고
    • Nuclear cloning of embryonal carcinoma cells
    • Blelloch, R. H. et al. Nuclear cloning of embryonal carcinoma cells. Proc. Natl Acad. Sci. USA 101, 13985-13990 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 13985-13990
    • Blelloch, R.H.1
  • 150
    • 3543073392 scopus 로고    scopus 로고
    • Reprogramming of a melanoma genome by nuclear transplantation
    • Hochedlinger, K. et al. Reprogramming of a melanoma genome by nuclear transplantation. Genes Dev. 18, 1875-1885 (2004).
    • (2004) Genes Dev , vol.18 , pp. 1875-1885
    • Hochedlinger, K.1
  • 151
    • 10744221485 scopus 로고    scopus 로고
    • In vivo activation of the p53 pathway by small-molecule antagonists of MDM2
    • Vassilev, L. T. et al. In vivo activation of the p53 pathway by small-molecule antagonists of MDM2. Science 303, 844-848 (2004).
    • (2004) Science , vol.303 , pp. 844-848
    • Vassilev, L.T.1
  • 152
    • 9144270205 scopus 로고    scopus 로고
    • Siah-1 facilitates ubiquitination and degradation of synphilin-1
    • Nagano, Y. et al. Siah-1 facilitates ubiquitination and degradation of synphilin-1. J. Biol. Chem. 278, 51504-51514 (2003).
    • (2003) J. Biol. Chem , vol.278 , pp. 51504-51514
    • Nagano, Y.1
  • 153
    • 11144358336 scopus 로고    scopus 로고
    • Ubiquitylation of synphilin-1 and α-synuclein by SIAH and its presence in cellular inclusions and Lewy bodies imply a role in Parkinson's disease
    • Liani, E. et al. Ubiquitylation of synphilin-1 and α-synuclein by SIAH and its presence in cellular inclusions and Lewy bodies imply a role in Parkinson's disease. Proc. Natl Acad. Sci. USA 101, 5500-5505 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 5500-5505
    • Liani, E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.