Epigenetics wins over genetics: Induction of differentiation in tumor cells

Seminars in Cancer Biology

Volumn 12, Issue 5, 2002, Pages 339-346

  Lotem, Joseph ^a   Sachs, Leo ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Cytokines; Differentiation; Epigenetic suppression of malignancy; Hematopoiesis; Leukemia; Tumor therapy

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; ARSENIC TRIOXIDE; BACTERIUM LIPOPOLYSACCHARIDE; BETA INTERFERON; BREFELDIN A; COLECALCIFEROL DERIVATIVE; COLONY STIMULATING FACTOR 1; CYTARABINE; DNA METHYLTRANSFERASE; FLT3 LIGAND; GLUCOCORTICOID; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HERBIMYCIN; HISTONE ACETYLTRANSFERASE; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; INSULIN; INTERLEUKIN 1; INTERLEUKIN 11; INTERLEUKIN 3; INTERLEUKIN 6; METHOTREXATE; ONCOSTATIN M; PHORBOL ESTER DERIVATIVE; RETINOIC ACID; RETINOIC ACID RECEPTOR ALPHA; STEM CELL FACTOR; TUMOR NECROSIS FACTOR; UNINDEXED DRUG;

ARTICLE; CANCER GENETICS; CELL DIFFERENTIATION; CYTOKINE PRODUCTION; DNA METHYLATION; GENE EXPRESSION; GENE SILENCING; HEMATOPOIESIS; HUMAN; LEUKEMIA CELL; MYELOID LEUKEMIA; NONHUMAN; PHENOTYPE; STEM CELL;

EID: 0036392034     PISSN: 1044579X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1044-579X(02)00054-8     Document Type: Article

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