Regulated ectopic expression of cyclin D1 induces transcriptional activation of the cdk inhibitor p21 gene without altering cell cycle progression

Oncogene

Volumn 14, Issue 21, 1997, Pages 2533-2542

  Hiyama, Hirofumi ^a   Iavarone, Antonio ^c   LaBaer, Joshua ^b   Reeves, Steven A ^a  

^a Neuroscience Center   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

Cell cycle; Cyclin D1; E2F; p21; Tetracycline; Transcription

Indexed keywords

CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR; PROTEIN P21; PROTEIN P53; TETRACYCLINE;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL CYCLE G1 PHASE; CELL GROWTH; CELL STRAIN 3T3; CONTROLLED STUDY; GENE AMPLIFICATION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; TRANSACTIVATION; TUMOR SUPPRESSOR GENE;

3T3 CELLS; ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; CARRIER PROTEINS; CELL CYCLE; CELL CYCLE PROTEINS; CELL DIVISION; CELL SIZE; CYCLIN D1; CYCLIN-DEPENDENT KINASE 4; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLIN-DEPENDENT KINASES; CYCLINS; DNA-BINDING PROTEINS; E2F TRANSCRIPTION FACTORS; E2F1 TRANSCRIPTION FACTOR; ENZYME INHIBITORS; FIBROBLASTS; GENE EXPRESSION REGULATION; GLIOMA; HUMANS; IMMUNOHISTOCHEMISTRY; MICE; MODELS, BIOLOGICAL; ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS; TETRACYCLINE; TIME FACTORS; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTOR DP1; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA; RODENTIA;

EID: 0030916486     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1201080     Document Type: Article

References (69)

1. Asai A, Miyagi Y, Sugiyama A, Gamanuma M, Hong SH, Takamoto S, Nomura K, Matsutani M, Takakura K and Kuchino Y. (1994). J. Neuro-Oncol., 19, 259-268.
2. Asano K, Sakamoto H, Sasaki H, Ochiya T, Yoshida T, Ohishi Y, Machida T, Kakizoe T, Sugimura T and Terada MH. (1995). Biochem. Biophys. Res. Commum., 217, 1169-1176.
3. Bagchi S, Weinmann R and Raychaudhuri P. (1991). Cell, 65, 1063-1072.
4. Baldwin V, Lukas J, Marcote MJ, Pagano M and Draetta G. (1993). Genes & Dev., 7, 812-821.
5. Bennet JD, Farlie PG and Watson RJ. (1996). Oncogene, 13, 1073-1082.
6. Bodrug SE, Warner BJ, Bath ML, Linderman GJ, Harris AW and Adams JM. (1994). EMBO J., 13, 2124-2130.
7. Chellappan SP, Hiebert S, Mudryj M, Horowitz JM and Nevins JR. (1991). Cell, 65, 1053-1061.
8. Chittenden T, Livingston D and Kaelin W. (1991). Cell, 65, 1073-1082.
9. Datto MB, Li Y, Panus JF, Howe DJ, Xiong Y and Wang XF. (1995). Proc. Natl. Acad. Sci. USA, 92, 5545-5549.
10. Dowdy SF, Hinds PW, Louie K, Reed SI, Arnold A and Weinberg RA. (1993). Cell, 73, 499-511.
11. Du W, Xie JE and Dyson N. (1996). EMBO J., 15, 3684-3692.
12. Dulic V, Kaufmann WK, Wilson SJ, Tlsty TD, Lees E, Harper JW, Elledge SJ and Reed SI. (1994). Cell, 76, 1013-1023.
13. El-Deiry W, Tokino T, Velculescu VE, Levy DB, Parsons R, Trent JM, Lin D, Mercer WE, Kinzler KW and Vogelstein B. (1993). Cell, 75, 817-825.
14. Ewen ME, Sluss HK, Sherr CJ, Matsushime H, Kato JY and Livingstone DM. (1993). Cell, 73, 487-497.
15. Fueyo J, Gomez-Manzano C, Yung WKA, Clayman GL, Liu TJ, Bruner J, Levin VA and Kyritsis AP. (1996). Oncogene, 12, 103-110.
16. Gomez-Manzano C, Fueyo J, Kyritsis AP, Steck PA, Roth JA, McDonnell TJ, Steck KD, Levin VA and Yung WKA. (1996). Cancer Res., 56, 694-699.
17. Gossen M and Bujard H. (1992). Proc. Natl. Acad. Sci. USA, 89, 5547-5551.
18. Halevy O, Novitch BG, Spicer DB, Skapek SX, Rhee J, Hannon GJ, Beach D and Lassar AB. (1995). Science, 267, 1018-1021.
19. Harper JW, Elledge SJ, Keyomarsi K, Dynlacht B, Tsai LH, Zhang P, Dobrowolski S, Bai C, Connel-Crowley L, Swindell E, Fox MP and Wei N. (1995). Mol. Biol. Cell, 6, 387-400.
20. He J, Allen JR, Collins VP, Allalunis-Turner MJ, Godbout R, Day III RS and James CD. (1994). Cancer Res., 54, 5804-5807.
21. Helin K, Wu CL, Fattaey AR, Lees JA, Dynlacht BD, Ngwu C and Harlow E. (1993). Genes & Dev., 7, 1850-1861.
22. Hinds PW, Mittnacht S, Dulic F, Arnold A, Reed SI and Weinberg RA. (1992). Cell, 70, 993-1006.
23. Horowitz JM, Park SH, Bogenmann E, Cheng JC, Yandell DW, Kaye FJ, Minna JD, Dryja TP and Weinberg RA. (1990). Proc. Natl. Acad. Sci. USA, 87, 2775-2779.
24. Huang HJ, Yee JK, Shew JY, Chen PL, Bookstein R, Fridmann T, Lee EY and Lee WH. (1988). Science, 242, 1563-1566.
25. Humer T. (1993). Cell, 75, 839-841.
26. Jiang H, Lin J, Su Zc, Collart FR, Huberman E and Fisher PB. (1994). Oncogene, 9, 3397-3406.
27. Jiang W, Kahn SM, Tomita N, Zhang YJ, Lu SH and Weinstein IB. (1992). Cancer Res., 52, 2980-2983.
28. Jiang W, Kahn SM, Zhou P, Zhang YJ, Cacace AM, Infante AS, Doi S, Santella RM and Weinstein IB. (1993). Oncogene, 8, 3447-3457.
29. Johnson DG. (1995). Oncogene, 11, 1685-1692.
30. Jung JM, Bruner JM, Rusan S, Langford LA, Kyritsis AP, Kobayashi T, Levin VA and Zhang W. (1995). Oncogene, 11, 2021-2028.
31. Kato JY, Matsushime H, Hiebert SW, Ewen ME and Sherr CJ. (1993). Genes & Dev., 7, 331-342.
32. Kamb A. (1995). Trend Genet., 11, 136-140.
33. Lammie GA, Fantl V, Smith R, Schuuring E, Brookes S, Michalides R, Dickson C, Arnold A and Peters G. (1991). Oncogene, 6, 439-444.
34. Lam EW, Bennet JD and Watson RJ. (1995). Gene, 160, 277-281.
35. Liu Y, Martindale JL, Gorospe M and Holbrook NJ. (1996). Cancer Res. 56, 31-35.
36. Lovec H, Sewing A, Lucibello FC, Muller R and Moroy T. (1993). Oncogene, 9, 323-326.
37. Macleod KF, Sherry N, Hannon G, Beach D, Tokino T, Kinzler K, Vogelstein B and Jacks T. (1995). Genes & Dev., 9, 935-944.
38. Marchetti A, Doglioni C, Barbareschi M, Buttitta F, Pellegrini S, Bertacca G, Chella A, Merlo G, Angeletti CA, Palma PD and BevilacquaGi. (1996). Oncogene, 12, 1319-1324.
39. Matsushime H, Quelle DE, Shurtleff SA, Shibuya M, Sherr CJ and Kato JY. (1994). Mol. Cell. Biol., 14, 2066-2076.
40. Meyerson M and Harlow E. (1994). Mol. Cell. Biol., 14, 2077-2086.
41. Michieli P, Li W, Lorenzi MV, Miki T, Zakut R, Givol D and Pierce JH. (1996). Oncogene, 12, 775-784.
42. Motokura T, Bloom T, Kim HG, Juppner H, Ruderman JV, Kronenberg HM and Arnold A. (1991). Nature, 350, 512-515.
43. Nevins JR. (1992). Science, 258, 424-429.
44. Ohtsubo M and Robers JM. (1993). Science, 259, 1908-1912.
45. Pardee AB. (1989). Science, 246, 603-608.
46. Parker SB, Eichele G, Zhang P, Rawls A, Sands AT, Bradley A, Olson EN, Harper JW and Elledge SJ. (1995). Science, 267, 1024-1027.
47. Paulus W, Baur I, Boyce FM, Breakefield XO and Reeves SA. (1996). J. Virol., 70, 62-67.
48. Pear WS, Nolan GP, Scott ML and Baltimore D. (1993). Proc. Natl. Acad. Sci. USA, 90, 8392-8396.
49. Quelle DE, Ashmun RA, Shurtleff SA, Kato JY, Bar-Sagi D, Roussel MF and Sherr CJ. (1993). Genes & Dev., 7, 1559-1571.
50. Resnitzky D, Gossen M, Bujard H and Reed SI. (1994). Mol. Cell. Biol., 14, 1669-1679.
51. Reynisdottir I, Polyak K, Iavarone A and Massague J. (1995). Genes & Dev., 9, 1831-1845.
52. Schulze A, Zerfab K, Spilkovsky D, Henglein B and Jansen-Durr P. (1994). Oncogene, 9, 3475-3482.
53. Schuuring E, Verhoeven E, Mooi WJ and Michalides R. (1992). Oncogene, 7, 355-361.
54. Sgambato A, Han EK, Zhou P, Schieren I and Weinstein IB. (1996). Cancer Res., 56, 1389-1399.
55. Shao Z and Robbins PD. (1995). Oncogene, 10, 221-228.
56. Sheikh MS, Li XS, Chen JC, Shao ZM, Ordonez JV and Fontana JA. (1994). Oncogene, 9, 3407-3415.
57. Sheikh MS, Rochefort H and Garcia M. (1995). Oncogene, 11, 1899-1905.
58. Sherr CJ. (1994). Cell, 79, 551-555.
59. Sherr CJ and Roberts M. (1995). Genes & Dev., 9, 1149-1163.
60. Steinman RA, Hoffman B, Iro A, Guillouf C, Liebermann DA and EI-Houseini ME. (1994). Oncngene, 9, 3389-3396.
61. Van Meir EG, Roemer K, Diserens AC, Kikuchi T, Rempel SA, Haas M, Su Huung HJ, Friedmann T, de Tribolet N and Cavenee WK. (1995). Proc. Natl. Acad. Sci. USA, 92, 1008-1012.
62. Wang TC, Cardiff RD, Zukerherg L, Lees E, Arnold A and Schmidt EV. (1994). Nature, 369, 669-671.
63. Weinberg RA. (1995). Cell, 81, 323-330.
64. Wolfel T, Hauer M, Schneider J, Serrano M, Wolfel C, Klehmann-Hieh E, De Plaen E, Hankeln T, Meyer KHB and Beach D. (1995). Science, 269, 1281-1284.
65. Xiong Y, Hannon GJ, Zhang H, Casso D, Kobayashi R and Beach D. (1993). Nature, 366, 701-704.
66. Wu CL, Zukerberg LR, Ngwu C, Harlow E and Lees JA. (1995). Mol. Cell. Biol., 15, 2536-2546.
67. Yang ZY, Perkins ND, Ohno T, Nabel EG and Nabel GJ. (1995). Nature Medicine, I, 1052-1056.
68. Zhang H, Hannon GJ and Beach D. (1994). Genes & Dev., 8, 1750-1758.
69. Zwijsen RM, Klompmaker R, Wientjens EB, Kristel PM, van der Burg B and Michalides R. (1996). Mol. Cell. Biol., 16, 2554-2560.