-
1
-
-
0027432424
-
Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: The role of phosphatidylinositol 3,4.5-trisphosphate in neutrophil responses
-
Arcaro, A., and M.P. Wymann. 1993. Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4.5-trisphosphate in neutrophil responses. Biochem. J. 296:297-301.
-
(1993)
Biochem. J.
, vol.296
, pp. 297-301
-
-
Arcaro, A.1
Wymann, M.P.2
-
2
-
-
0023150655
-
Inhibition of the phagocytosis-induced respiratory burst by the fungal metabolite wortmannin and some analogues
-
Baggiolini, M., B. Dewald, J. Schnyder, W. Ruch, P.M. Cooper, and T.G. Payne. 1987. Inhibition of the phagocytosis-induced respiratory burst by the fungal metabolite wortmannin and some analogues. Exp. Cell Res. 169:408-418.
-
(1987)
Exp. Cell Res.
, vol.169
, pp. 408-418
-
-
Baggiolini, M.1
Dewald, B.2
Schnyder, J.3
Ruch, W.4
Cooper, P.M.5
Payne, T.G.6
-
3
-
-
0029115917
-
Wortmannin blocks lipid and protein kinase activities associated with PI 3-kinase and inhibits a subset of responses induced by FceR1 cross-linking
-
Barker, S.A., K.K. Caldwell, A. Hall, A.M. Martinez, J.R. Pfeiffer, J.M. Oliver, and B.S. Wilson. 1995. Wortmannin blocks lipid and protein kinase activities associated with PI 3-kinase and inhibits a subset of responses induced by FceR1 cross-linking. Mol. Biol. Cell. 6:1145-1158.
-
(1995)
Mol. Biol. Cell.
, vol.6
, pp. 1145-1158
-
-
Barker, S.A.1
Caldwell, K.K.2
Hall, A.3
Martinez, A.M.4
Pfeiffer, J.R.5
Oliver, J.M.6
Wilson, B.S.7
-
4
-
-
0029079633
-
Molecular size-fractionation during endocylosis in macrophages
-
Berthiaume, E.P., C. Medina, and J.A. Swanson. 1995. Molecular size-fractionation during endocylosis in macrophages. J. Cell Biol. 129:989-998.
-
(1995)
J. Cell Biol.
, vol.129
, pp. 989-998
-
-
Berthiaume, E.P.1
Medina, C.2
Swanson, J.A.3
-
5
-
-
0029148577
-
Role for phosphatidylinositol 3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cells
-
Brown, W.J., D.B. DeWald, S.D. Emr, H. Plutner, and W.E. Balch. 1995. Role for phosphatidylinositol 3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cells. J. Cell Biol. 130:781-796.
-
(1995)
J. Cell Biol.
, vol.130
, pp. 781-796
-
-
Brown, W.J.1
DeWald, D.B.2
Emr, S.D.3
Plutner, H.4
Balch, W.E.5
-
6
-
-
0026069474
-
Oncogenes and signal transduction
-
Cantley, L.C., K.R. Auger, C. Carpenter, B. Duckworth, A. Graziani, R. Kapeller, and S. Soltoff. 1991. Oncogenes and signal transduction. Cell. 64:281-302.
-
(1991)
Cell
, vol.64
, pp. 281-302
-
-
Cantley, L.C.1
Auger, K.R.2
Carpenter, C.3
Duckworth, B.4
Graziani, A.5
Kapeller, R.6
Soltoff, S.7
-
7
-
-
0025966971
-
The role of kinase activity and the kinase insert region in ligand-induced internalization and degradation of the c-fms protein
-
Carlberg, K., P. Tapley, C. Haystead. and L. Rohrschneider. 1991. The role of kinase activity and the kinase insert region in ligand-induced internalization and degradation of the c-fms protein. EMBO (Eur. Mol. Biol. Organ.) J. 10:877-883.
-
(1991)
EMBO (Eur. Mol. Biol. Organ.) J.
, vol.10
, pp. 877-883
-
-
Carlberg, K.1
Tapley, P.2
Haystead, C.3
Rohrschneider, L.4
-
8
-
-
0028979563
-
Phosphatidylinositol 3-kinase regulation of fluid phase endocytosis
-
Clague, M.J., C. Thorpe, and A.T. Jones. 1995. Phosphatidylinositol 3-kinase regulation of fluid phase endocytosis. FEBS Lett. 367:272-274.
-
(1995)
FEBS Lett.
, vol.367
, pp. 272-274
-
-
Clague, M.J.1
Thorpe, C.2
Jones, A.T.3
-
9
-
-
0021281853
-
Stimulation of phagocytosis in bone marrow-derived mouse macrophages by bacterial lipopolysaccharide: Correlation with biochemical and functional parameters
-
Cooper, P.M., P. Mayer, and M. Baggiolini. 1984. Stimulation of phagocytosis in bone marrow-derived mouse macrophages by bacterial lipopolysaccharide: correlation with biochemical and functional parameters. J. Immunol. 133:913-922.
-
(1984)
J. Immunol.
, vol.133
, pp. 913-922
-
-
Cooper, P.M.1
Mayer, P.2
Baggiolini, M.3
-
10
-
-
0029123267
-
Wortmannin causes mistargeting of procathepsin D. Evidence for the involvement of a phosphatidylinositol 3-kinase in vesicular transport to lysosomes
-
Davidson, H.W. 1995. Wortmannin causes mistargeting of procathepsin D. Evidence for the involvement of a phosphatidylinositol 3-kinase in vesicular transport to lysosomes. J. Cell Biol. 130:797-805.
-
(1995)
J. Cell Biol.
, vol.130
, pp. 797-805
-
-
Davidson, H.W.1
-
11
-
-
0029968296
-
Phosphoinositides as regulators of membrane traffic
-
de Camilli, P., S.D. Emr, P.S. McPherson, and P. Novick. 1996. Phosphoinositides as regulators of membrane traffic. Science (Wash. DC). 271:1533-1539.
-
(1996)
Science (Wash. DC)
, vol.271
, pp. 1533-1539
-
-
De Camilli, P.1
Emr, S.D.2
McPherson, P.S.3
Novick, P.4
-
12
-
-
0022976304
-
Acetylated low-density lipoprotein is endocytosed through coaled pits by rat peritoneal macrophages
-
Fukuda, S., S. Horiuchi, K. Tomita, M. Murakami, Y. Morino, and K. Takahashi. 1986. Acetylated low-density lipoprotein is endocytosed through coaled pits by rat peritoneal macrophages. Virchows Arch. 52:1-13.
-
(1986)
Virchows Arch.
, vol.52
, pp. 1-13
-
-
Fukuda, S.1
Horiuchi, S.2
Tomita, K.3
Murakami, M.4
Morino, Y.5
Takahashi, K.6
-
13
-
-
0009627006
-
Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition
-
Goldstein, J.L., Y.K. Ho, S.K. Basu, and M.S. Brown. 1979. Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition. Proc. Natl. Acatl. Sci. USA. 76:333-337.
-
(1979)
Proc. Natl. Acatl. Sci. USA
, vol.76
, pp. 333-337
-
-
Goldstein, J.L.1
Ho, Y.K.2
Basu, S.K.3
Brown, M.S.4
-
14
-
-
0027362241
-
The GTPase dynamin binds to and is activated by a subset of SH3 domains
-
Gout, I., R. Dhand, I.D. Hiles, M.J. Fry, G. Panayotou, P. Das, O. Truong, N.F. Totty, J. Hsuan, G.W. Booker, I.D. Campbell, and M.D. Waterfield. 1993. The GTPase dynamin binds to and is activated by a subset of SH3 domains. Cell. 75:25-36.
-
(1993)
Cell
, vol.75
, pp. 25-36
-
-
Gout, I.1
Dhand, R.2
Hiles, I.D.3
Fry, M.J.4
Panayotou, G.5
Das, P.6
Truong, O.7
Totty, N.F.8
Hsuan, J.9
Booker, G.W.10
Campbell, I.D.11
Waterfield, M.D.12
-
15
-
-
0028925751
-
Signal transduction of phagocytosis
-
Greenberg, S. 1995. Signal transduction of phagocytosis. Trends Cell Biol. 5:93-99.
-
(1995)
Trends Cell Biol.
, vol.5
, pp. 93-99
-
-
Greenberg, S.1
-
16
-
-
0029058288
-
Phosphatidylinositol 3-kinase activity is required at a post-endocytic step in platelet-derived growth factor receptor trafficking
-
Joly, M., A. Kazlauskas, and S. Corvera. 1995. Phosphatidylinositol 3-kinase activity is required at a post-endocytic step in platelet-derived growth factor receptor trafficking. J. Biol. Chem. 270:13225-13230.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 13225-13230
-
-
Joly, M.1
Kazlauskas, A.2
Corvera, S.3
-
17
-
-
0025177343
-
Type I macrophage scavenger receptor contains α-helical and collagen-like coiled-coils
-
Kodama, T., M. Freeman, L. Rohrer, J. Zabrecky, P. Matsudaira, and M. Krieger. 1990. Type I macrophage scavenger receptor contains α-helical and collagen-like coiled-coils. Nature (Lond.). 343:531-535.
-
(1990)
Nature (Lond.)
, vol.343
, pp. 531-535
-
-
Kodama, T.1
Freeman, M.2
Rohrer, L.3
Zabrecky, J.4
Matsudaira, P.5
Krieger, M.6
-
18
-
-
0028264058
-
Involvement of phosphoinositide 3-kinase in insulin- Or IGF-1-induced membrane ruffling
-
Kotani, K., K. Yonezawa, K. Hara, H. Ueda, Y. Kitamura, H. Sakaue, A. Ando, A. Chavanieu, B. Calas, F. Grigorescu, M. Nishiyama, M.D. Waterfield, and M. Kasuga. 1994. Involvement of phosphoinositide 3-kinase in insulin-or IGF-1-induced membrane ruffling. EMBO (Eur. Mol. Biol. Organ.) J. 13:2313-2321.
-
(1994)
EMBO (Eur. Mol. Biol. Organ.) J.
, vol.13
, pp. 2313-2321
-
-
Kotani, K.1
Yonezawa, K.2
Hara, K.3
Ueda, H.4
Kitamura, Y.5
Sakaue, H.6
Ando, A.7
Chavanieu, A.8
Calas, B.9
Grigorescu, F.10
Nishiyama, M.11
Waterfield, M.D.12
Kasuga, M.13
-
19
-
-
0028786852
-
Evidence for phosphatidylinositol 3-kinase as a regulator of endocytosis via activation of Rab5
-
Li, G., C. D'Souza-Schorey, M.A. Barbieri, R.L. Roberts, A. Klippel, L.T. Williams, and P.D. Stahl. 1995. Evidence for phosphatidylinositol 3-kinase as a regulator of endocytosis via activation of Rab5. Proc. Natl. Acad. Sci. USA. 92:10207-10211.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 10207-10211
-
-
Li, G.1
D'Souza-Schorey, C.2
Barbieri, M.A.3
Roberts, R.L.4
Klippel, A.5
Williams, L.T.6
Stahl, P.D.7
-
20
-
-
0029019442
-
Signal transduction and membrane traffic: The PITP/phosphoinositide connection
-
Liscovitch, M., and L.C. Cantley. 1995. Signal transduction and membrane traffic: the PITP/phosphoinositide connection. Cell. 81:659-662.
-
(1995)
Cell
, vol.81
, pp. 659-662
-
-
Liscovitch, M.1
Cantley, L.C.2
-
21
-
-
0029015694
-
A wortmannin-sensitive phosphatidylinositol 4-kinase that regulates hormone-sensitive pools of inositol phospholipids
-
Nakanishi, S., K.J. Catl, and T. Balla. 1995. A wortmannin-sensitive phosphatidylinositol 4-kinase that regulates hormone-sensitive pools of inositol phospholipids. Proc. Natl. Acad. Sci. USA. 92:5317-5321.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 5317-5321
-
-
Nakanishi, S.1
Catl, K.J.2
Balla, T.3
-
22
-
-
0027933578
-
Involvement of phosphatidylinositol 3-kinase in Fey receptor signaling
-
Ninomiya, N., K. Hazeki, Y. Fukui, T. Seya, T. Okada, O. Hazeki, and M. Ui. 1994. Involvement of phosphatidylinositol 3-kinase in Fey receptor signaling. J. Biol. Chem. 269:22732-22737.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 22732-22737
-
-
Ninomiya, N.1
Hazeki, K.2
Fukui, Y.3
Seya, T.4
Okada, T.5
Hazeki, O.6
Ui, M.7
-
23
-
-
0024394044
-
Macrophage colony-stimulating factor (rM-CSF) stimulates pinocytosis in bone marrow-derived macrophages
-
Racoosin, E.L., and J.A. Swanson. 1989. Macrophage colony-stimulating factor (rM-CSF) stimulates pinocytosis in bone marrow-derived macrophages. J. Exp. Med. 170:1635-1648.
-
(1989)
J. Exp. Med.
, vol.170
, pp. 1635-1648
-
-
Racoosin, E.L.1
Swanson, J.A.2
-
24
-
-
0026776006
-
M-CSF-induced macropinocytosis increases solute endocylosis but not receptor-mediated endocytosis in mouse macrophages
-
Racoosin, E.L., and J.A. Swanson. 1992. M-CSF-induced macropinocytosis increases solute endocylosis but not receptor-mediated endocytosis in mouse macrophages. J. Cell Sci. 102:867-880.
-
(1992)
J. Cell Sci.
, vol.102
, pp. 867-880
-
-
Racoosin, E.L.1
Swanson, J.A.2
-
25
-
-
0027905021
-
Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting
-
Schu, P.V., K. Takegawa, M.J. Fry, J.H. Stack, M.D. Waterfield, and S.D. Emr. 1993. Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting. Science (Wash. DC). 260:88-91.
-
(1993)
Science (Wash. DC)
, vol.260
, pp. 88-91
-
-
Schu, P.V.1
Takegawa, K.2
Fry, M.J.3
Stack, J.H.4
Waterfield, M.D.5
Emr, S.D.6
-
26
-
-
0029075197
-
Inhibitors of phosphoinositide 3-kinase block exocytosis but not endocytosis of transferrin receptors in 3T3-LI adipocytes
-
Shepherd, P.R., M.A. Soos, and K. Siddle. 1995. Inhibitors of phosphoinositide 3-kinase block exocytosis but not endocytosis of transferrin receptors in 3T3-LI adipocytes. Biachem. Biophys. Res. Comm. 211:535-539.
-
(1995)
Biachem. Biophys. Res. Comm.
, vol.211
, pp. 535-539
-
-
Shepherd, P.R.1
Soos, M.A.2
Siddle, K.3
-
28
-
-
0030027394
-
Potential sites of PI-3 kinase function in the endocylic pathway revealed by the PI-3 kinase inhibitor, wortmannin
-
Shpetner, H., M. Joly, D. Hartley, and S. Corvera. 1996. Potential sites of PI-3 kinase function in the endocylic pathway revealed by the PI-3 kinase inhibitor, wortmannin. J. Cell Biol. 132:595-605.
-
(1996)
J. Cell Biol.
, vol.132
, pp. 595-605
-
-
Shpetner, H.1
Joly, M.2
Hartley, D.3
Corvera, S.4
-
29
-
-
0029933270
-
Wortmannin alters the transferrin receptor endocylic pathway in vivo and in vitro
-
Spiro, D.J., W. Boll, T. Kirchhausen, and M. Wessling-Resnick. 1996. Wortmannin alters the transferrin receptor endocylic pathway in vivo and in vitro. Mol. Biol. Cell. 7:355-367.
-
(1996)
Mol. Biol. Cell
, vol.7
, pp. 355-367
-
-
Spiro, D.J.1
Boll, W.2
Kirchhausen, T.3
Wessling-Resnick, M.4
-
30
-
-
0024431785
-
Phorbol esters stimulate macropinocytosis and solute flow through macrophages
-
Swanson, J.A. 1989. Phorbol esters stimulate macropinocytosis and solute flow through macrophages. J. Cell Sci. 94:135-142.
-
(1989)
J. Cell Sci.
, vol.94
, pp. 135-142
-
-
Swanson, J.A.1
-
31
-
-
0028912192
-
Phagocytosis by zippers and triggers
-
Swanson, J.A., and S.C. Baer. 1995. Phagocytosis by zippers and triggers. Trends Cell Biol. 5:89-93.
-
(1995)
Trends Cell Biol.
, vol.5
, pp. 89-93
-
-
Swanson, J.A.1
Baer, S.C.2
-
33
-
-
0028321727
-
Wortmannin binds specifically to 1-phosphatidylinositol 3-kinase while inhibiting guanine nucleotide-binding protein-coupled receptor signaling in neutrophil leukocytes
-
Thelen, M., M.P. Wymann.and H. Langen. 1994. Wortmannin binds specifically to 1-phosphatidylinositol 3-kinase while inhibiting guanine nucleotide-binding protein-coupled receptor signaling in neutrophil leukocytes. Proc. Natl. Acad. Sci. USA. 91:4960-4964.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 4960-4964
-
-
Thelen, M.1
Wymann, M.P.2
Langen, H.3
-
34
-
-
0027203046
-
Mutations in human dynamin block an intermediate stage in coated vesicle formation
-
van der Bliek, A.M., T.E. Redelmeier, H. Damke, E.J. Tisdale, E.M. Meycrowitz, and S.L. Schmid. 1993. Mutations in human dynamin block an intermediate stage in coated vesicle formation. L Cell Biol. 122:553-563.
-
(1993)
L Cell Biol.
, vol.122
, pp. 553-563
-
-
Van der Bliek, A.M.1
Redelmeier, T.E.2
Damke, H.3
Tisdale, E.J.4
Meycrowitz, E.M.5
Schmid, S.L.6
-
35
-
-
0028170210
-
A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4Hl-benzopyran-4-one (LY294002)
-
Vlahos, C.J., W.F. Matter, K.Y. Hui, and R.F. Brown. 1994. A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4Hl-benzopyran-4-one (LY294002). J. Biol. Chem. 269:5241-5248.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 5241-5248
-
-
Vlahos, C.J.1
Matter, W.F.2
Hui, K.Y.3
Brown, R.F.4
-
36
-
-
0028429961
-
Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling
-
Wennström, S., P. Howkins, F. Cooke, K. Hara, K. Yonezawa, M. Kasuga. T. Jackson, L. Claesson-Welsh, and L. Stephens. 1994. Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling. Curr. Biol. 4:385-393.
-
(1994)
Curr. Biol.
, vol.4
, pp. 385-393
-
-
Wennström, S.1
Howkins, P.2
Cooke, F.3
Hara, K.4
Yonezawa, K.5
Kasuga, M.6
Jackson, T.7
Claesson-Welsh, L.8
Stephens, L.9
-
37
-
-
0019971133
-
Tumor-promoting phorbol esters stimulate C3b and C3b′ receptor-mediated phagocytosis in cultured human monocytes
-
Wright, S.D., and S.C. Silverslein. 1982. Tumor-promoting phorbol esters stimulate C3b and C3b′ receptor-mediated phagocytosis in cultured human monocytes. J. Exp. Med. 156:1149-1164.
-
(1982)
J. Exp. Med.
, vol.156
, pp. 1149-1164
-
-
Wright, S.D.1
Silverslein, S.C.2
-
38
-
-
0027374488
-
Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells
-
Yano, H., S. Nakanishi, K. Kimura, N. Hanai, Y. Saitoh, Y. Fukui, Y. Nonomura, and Y. Matsuda. 1993. Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells. J. Biol. Chem. 268:25846-25856.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 25846-25856
-
-
Yano, H.1
Nakanishi, S.2
Kimura, K.3
Hanai, N.4
Saitoh, Y.5
Fukui, Y.6
Nonomura, Y.7
Matsuda, Y.8
-
39
-
-
0028791442
-
Biochemical and pharmacological studies with KT7692 and LY294002 on the role of phosphatidylinositol 3-kinase in FcεR1-medialed signal transduction
-
Yano, H., T. Agatsuma, S. Nakanishi, Y. Saitoh, Y. Fukui, Y. Nonomura, and Y. Matsuda. 1995. Biochemical and pharmacological studies with KT7692 and LY294002 on the role of phosphatidylinositol 3-kinase in FcεR1-medialed signal transduction. Biochem. J. 312:145-150.
-
(1995)
Biochem. J.
, vol.312
, pp. 145-150
-
-
Yano, H.1
Agatsuma, T.2
Nakanishi, S.3
Saitoh, Y.4
Fukui, Y.5
Nonomura, Y.6
Matsuda, Y.7
|