Efficient gene transfer by pullulan-spermine occurs through both clathrin- and raft/caveolae-dependent mechanisms

Journal of Controlled Release

Volumn 116, Issue 1, 2006, Pages 75-82

  Kanatani, Isao ^a,b   Ikai, Tomonori ^b,c   Okazaki, Arimichi ^b   Jo, Jun ichiro ^b   Yamamoto, Masaya ^b   Imamura, Masaaki ^a,b   Kanematsu, Akihiro ^a,b   Yamamoto, Shingo ^d   Ito, Noriyuki ^a   Ogawa, Osamu ^a   Tabata, Yasuhiko ^b  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c OSAKA INSTITUTE OF TECHNOLOGY   (Japan)

^d HYOGO COLLEGE OF MEDICINE   (Japan)

Author keywords

Clathrin; Endocytosis; Gene transfer; Pullulan spermine; Raft caveolae

Indexed keywords

CONTROLLED DRUG DELIVERY; CYTOLOGY; DNA; DRUG PRODUCTS; POLYSACCHARIDES; TOXICITY;

CLATHRIN; ENDOCYTOSIS; PULLULAN SPERMINE; RAFT/CAVEOLAE;

GENE TRANSFER;

CHLORPROMAZINE; CLATHRIN; FILIPIN; LIPOFECTAMINE; PLASMID DNA; POLYSACCHARIDE; PROTEIN P53; PULLULAN SPERMINE; RECOMBINANT DNA; UNCLASSIFIED DRUG;

ARTICLE; CAVEOLA; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; DNA TRANSFECTION; ENDOCYTOSIS; GENE EXPRESSION; GENE TRANSFER; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE;

ASIALOGLYCOPROTEIN RECEPTOR; CAVEOLAE; CELL DIVISION; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; CLATHRIN; DNA; DRUG CARRIERS; FLOW CYTOMETRY; GENE TRANSFER TECHNIQUES; GENES, P53; GLUCANS; HUMANS; LUCIFERASES; MICROSCOPY, CONFOCAL; PLASMIDS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; SPERMINE; TRANSFECTION;

EID: 33751247920     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2006.09.001     Document Type: Article

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