Quantitative comparison of polyethylenimine formulations and adenoviral vectors in terms of intracellular gene delivery processes

Gene Therapy

Volumn 12, Issue 13, 2005, Pages 1023-1032

  Varga, C M ^a   Tedford, N C ^a   Thomas, M ^a   Klibanov, A M ^a   Griffith, L G ^a,b   Lauffenburger, D A ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b Massachusetts Institute of Technology   (United States)

Author keywords

Liver; Mathematical model; Molecular conjugates; Trafficking

Indexed keywords

ADENOVIRUS VECTOR; BETA GALACTOSIDASE; LIPOFECTAMINE; LIPOSOME; NAKED DNA; PLASMID DNA; POLYETHYLENEIMINE; POLYETHYLENEIMINE DERIVATIVE; VIRUS PROTEIN;

ARTICLE; BINDING AFFINITY; CARCINOMA CELL; CELL LYSATE; CONTROLLED STUDY; CYTOMEGALOVIRUS; ENDOSOME; GENE DELETION; GENE DELIVERY SYSTEM; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOGENICITY; INTRACELLULAR TRANSPORT; LIVER CELL CARCINOMA; MATHEMATICAL MODEL; NONVIRAL GENE DELIVERY SYSTEM; NUCLEAR IMPORT; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SENSITIVITY ANALYSIS; TRANSGENE; VIRAL GENE DELIVERY SYSTEM;

ADENOVIRIDAE; CELL LINE; GENE EXPRESSION; GENE THERAPY; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HUMANS; LIPOSOMES; LIVER; MODELS, GENETIC; PLASMIDS; POLYETHYLENEIMINE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; TRANSFECTION; TRANSGENES;

ADENOVIRIDAE; CUCUMBER MOSAIC VIRUS;

EID: 21744462256     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3302495     Document Type: Article

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