-
1
-
-
0032478696
-
Structural conservation in prokaryotic and eukaryotic potassium channels
-
MacKinnon, R., Cohen, S. L., Kuo, A., Lee, A., and Chait, B. T. (1998) Structural conservation in prokaryotic and eukaryotic potassium channels. Science 280, 106-109.
-
(1998)
Science
, vol.280
, pp. 106-109
-
-
MacKinnon, R.1
Cohen, S.L.2
Kuo, A.3
Lee, A.4
Chait, B.T.5
-
2
-
-
0036701872
-
Structural basis of inward rectifying potassium channel gating
-
Loussouarn, G., Rose, T., and Nichols, C. G. (2002) Structural basis of inward rectifying potassium channel gating. Trends CardioVasc. Med. 12, 253-258.
-
(2002)
Trends CardioVasc. Med
, vol.12
, pp. 253-258
-
-
Loussouarn, G.1
Rose, T.2
Nichols, C.G.3
-
3
-
-
0034489180
-
Intracellular regulation of inward rectifier K+ channels
-
Ruppersberg, J. P. (2000) Intracellular regulation of inward rectifier K+ channels. Pfluegers Arch. 441, 1-11.
-
(2000)
Pfluegers Arch
, vol.441
, pp. 1-11
-
-
Ruppersberg, J.P.1
-
4
-
-
12444274301
-
Crystal structure of the potassium channel KirBac1.1 in the closed state
-
Kuo, A., Gulbis, J. M., Antcliff, J. F., Rahman, T., Lowe, E. D., Zimmer, J., Cuthbertson, J., Ashcroft, F. M., Ezaki, T., and Doyle, D. A. (2003) Crystal structure of the potassium channel KirBac1.1 in the closed state. Science 300, 1922-1926.
-
(2003)
Science
, vol.300
, pp. 1922-1926
-
-
Kuo, A.1
Gulbis, J.M.2
Antcliff, J.F.3
Rahman, T.4
Lowe, E.D.5
Zimmer, J.6
Cuthbertson, J.7
Ashcroft, F.M.8
Ezaki, T.9
Doyle, D.A.10
-
5
-
-
26444584556
-
Two different conformational states of the KirBac3.1 potassium channel revealed by electron crystallography
-
Kuo, A., Domene, C., Johnson, L. N., Doyle, D. A., and Venien-Bryan, C. (2005) Two different conformational states of the KirBac3.1 potassium channel revealed by electron crystallography. Structure 13, 1463-1472.
-
(2005)
Structure
, vol.13
, pp. 1463-1472
-
-
Kuo, A.1
Domene, C.2
Johnson, L.N.3
Doyle, D.A.4
Venien-Bryan, C.5
-
6
-
-
0030609143
-
Octameric stoichiometry of the KATP channel complex
-
Shyng, S., and Nichols, C. G (1997) Octameric stoichiometry of the KATP channel complex. J. Gen. Physiol. 110, 655-664.
-
(1997)
J. Gen. Physiol
, vol.110
, pp. 655-664
-
-
Shyng, S.1
Nichols, C.G.2
-
7
-
-
33645322386
-
KATP channels as molecular sensors of cellular metabolism
-
Nichols, C. G (2006) KATP channels as molecular sensors of cellular metabolism. Nature 440, 470-476.
-
(2006)
Nature
, vol.440
, pp. 470-476
-
-
Nichols, C.G.1
-
8
-
-
41149095488
-
How membrane proteins sense voltage
-
Bezanilla, F. (2008) How membrane proteins sense voltage. Nat. ReV. Mol. Cell Biol. 9, 323-332.
-
(2008)
Nat. ReV. Mol. Cell Biol
, vol.9
, pp. 323-332
-
-
Bezanilla, F.1
-
9
-
-
25644437209
-
Focused electric field across the voltage sensor of potassium channels
-
Ahern, C. A., and Horn, R. (2005) Focused electric field across the voltage sensor of potassium channels. Neuron 48, 25-29.
-
(2005)
Neuron
, vol.48
, pp. 25-29
-
-
Ahern, C.A.1
Horn, R.2
-
10
-
-
0037282379
-
The voltage sensor and the gate in ion channels
-
Bezanilla, F., and Perozo, E. (2003) The voltage sensor and the gate in ion channels. Adv. Protein Chem. 63, 211-241.
-
(2003)
Adv. Protein Chem
, vol.63
, pp. 211-241
-
-
Bezanilla, F.1
Perozo, E.2
-
11
-
-
33745216690
-
A structural interpretation of voltage-gated potassium channel inactivation
-
Kurata, H. T., and Fedida, D. (2006) A structural interpretation of voltage-gated potassium channel inactivation. Prog. Biophys. Mol. Biol. 92, 185-208.
-
(2006)
Prog. Biophys. Mol. Biol
, vol.92
, pp. 185-208
-
-
Kurata, H.T.1
Fedida, D.2
-
12
-
-
0025224223
-
Biophysical and molecular mechanisms of Shaker potassium channel inactivation
-
Hoshi, T., Zagotta, W. N., and Aldrich, R. W. (1990) Biophysical and molecular mechanisms of Shaker potassium channel inactivation. Science 250, 533-538.
-
(1990)
Science
, vol.250
, pp. 533-538
-
-
Hoshi, T.1
Zagotta, W.N.2
Aldrich, R.W.3
-
13
-
-
0035822048
-
Potassium channel receptor site for the inactivation gate and quaternary amine inhibitors
-
Zhou, M., Morais-Cabral, J. H., Mann, S., and MacKinnon, R. (2001) Potassium channel receptor site for the inactivation gate and quaternary amine inhibitors. Nature 411, 657-661.
-
(2001)
Nature
, vol.411
, pp. 657-661
-
-
Zhou, M.1
Morais-Cabral, J.H.2
Mann, S.3
MacKinnon, R.4
-
14
-
-
0026079907
-
Tetraethylammonium blockade distinguishes two inactivation mechanisms in voltage-activated K+ channels
-
Choi, K. L., Aldrich, R. W., and Yellen, G. (1991) Tetraethylammonium blockade distinguishes two inactivation mechanisms in voltage-activated K+ channels. Proc. Natl. Acad. Sci. U.S.A. 88, 5092-5095.
-
(1991)
Proc. Natl. Acad. Sci. U.S.A
, vol.88
, pp. 5092-5095
-
-
Choi, K.L.1
Aldrich, R.W.2
Yellen, G.3
-
16
-
-
33646358260
-
A voltage-gated proton-selective channel lacking the pore domain
-
Ramsey, I. S., Moran, M. M., Chong, J. A., and Clapham, D. E. (2006) A voltage-gated proton-selective channel lacking the pore domain. Nature 440, 1213-1216.
-
(2006)
Nature
, vol.440
, pp. 1213-1216
-
-
Ramsey, I.S.1
Moran, M.M.2
Chong, J.A.3
Clapham, D.E.4
-
17
-
-
21744438625
-
Phosphoinositide phosphatase activity coupled to an intrinsic voltage sensor
-
Murata, Y., Iwasaki, H., Sasaki, M., Inaba, K., and Okamura, Y. (2005) Phosphoinositide phosphatase activity coupled to an intrinsic voltage sensor. Nature 435, 1239-1243.
-
(2005)
Nature
, vol.435
, pp. 1239-1243
-
-
Murata, Y.1
Iwasaki, H.2
Sasaki, M.3
Inaba, K.4
Okamura, Y.5
-
18
-
-
33646586039
-
Voltage-gated potassium channels: Regulation by accessory subunits
-
Li, Y., Um, S. Y., and McDonald, T. V. (2006) Voltage-gated potassium channels: Regulation by accessory subunits. Neuroscientist 12, 199-210.
-
(2006)
Neuroscientist
, vol.12
, pp. 199-210
-
-
Li, Y.1
Um, S.Y.2
McDonald, T.V.3
-
20
-
-
0029854263
-
Ks potassium channel
-
Ks potassium channel. Nature 384, 80-83.
-
(1996)
Nature
, vol.384
, pp. 80-83
-
-
Sanguinetti, M.C.1
Curran, M.E.2
Zou, A.3
Shen, J.4
Spector, P.S.5
Atkinson, D.L.6
Keating, M.T.7
-
22
-
-
33747723381
-
The KCNE2 potassium channel ancillary subunit is essential for gastric acid secretion
-
Roepke, T. K., Anantharam, A., Kirchhoff, P., Busque, S. M., Young, J. B., Geibel, J. P., Lerner, D. J., and Abbott, G W. (2006) The KCNE2 potassium channel ancillary subunit is essential for gastric acid secretion. J. Biol. Chem. 281, 23740-23747.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 23740-23747
-
-
Roepke, T.K.1
Anantharam, A.2
Kirchhoff, P.3
Busque, S.M.4
Young, J.B.5
Geibel, J.P.6
Lerner, D.J.7
Abbott, G.W.8
-
23
-
-
0034642569
-
A constitutively open potassium channel formed by KCNQ1 and KCNE3
-
Schroeder, B. C., Waldegger, S., Fehr, S., Bleich, M., Warth, R., Greger, R., and Jentsch, T. J. (2000) A constitutively open potassium channel formed by KCNQ1 and KCNE3. Nature 403, 196-199.
-
(2000)
Nature
, vol.403
, pp. 196-199
-
-
Schroeder, B.C.1
Waldegger, S.2
Fehr, S.3
Bleich, M.4
Warth, R.5
Greger, R.6
Jentsch, T.J.7
-
28
-
-
33744970273
-
Modulation of voltage-dependent Shaker family potassium channels by an aldoketo reductase
-
Weng, J., Cao, Y., Moss, N., and Zhou, M. (2006) Modulation of voltage-dependent Shaker family potassium channels by an aldoketo reductase. J. Biol. Chem. 281, 15194-15200.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 15194-15200
-
-
Weng, J.1
Cao, Y.2
Moss, N.3
Zhou, M.4
-
29
-
-
0032478818
-
+ conduction and selectivity
-
+ conduction and selectivity. Science 280, 69-77.
-
(1998)
Science
, vol.280
, pp. 69-77
-
-
Doyle, D.A.1
Morais Cabral, J.2
Pfuetzner, R.A.3
Kuo, A.4
Gulbis, J.M.5
Cohen, S.L.6
Chait, B.T.7
MacKinnon, R.8
-
33
-
-
0025743037
-
Interaction between tetraethylammonium and amino acid residues in the pore of cloned voltage-dependent potassium channels
-
Kavanaugh, M. P., Varnum, M. D., Osborne, P. B., Christie, M. J., Busch, A. E., Adelman, J. P., and North, R. A. (1991) Interaction between tetraethylammonium and amino acid residues in the pore of cloned voltage-dependent potassium channels. J. Biol. Chem. 266, 7583-7587.
-
(1991)
J. Biol. Chem
, vol.266
, pp. 7583-7587
-
-
Kavanaugh, M.P.1
Varnum, M.D.2
Osborne, P.B.3
Christie, M.J.4
Busch, A.E.5
Adelman, J.P.6
North, R.A.7
-
38
-
-
0028276482
-
+ channel: Peptide and channel residues mediating molecular recognition
-
+ channel: Peptide and channel residues mediating molecular recognition. Neuron 12, 1377-1388.
-
(1994)
Neuron
, vol.12
, pp. 1377-1388
-
-
Goldstein, S.A.1
Pheasant, D.J.2
Miller, C.3
-
39
-
-
34548615505
-
-
+ Channel Complexes. ACS Chem. Biol. 2, 469-473.
-
+ Channel Complexes. ACS Chem. Biol. 2, 469-473.
-
-
-
-
40
-
-
0018860646
-
A covalently bound photoisomerizable agonist: Comparison with reversibly bound agonists at Electrophorus electroplaques
-
Lester, H. A., Krouse, M. E., Nass, M. M., Wassermann, N. H., and Erlanger, B. F. (1980) A covalently bound photoisomerizable agonist: Comparison with reversibly bound agonists at Electrophorus electroplaques. J. Gen. Physiol. 75, 207-232.
-
(1980)
J. Gen. Physiol
, vol.75
, pp. 207-232
-
-
Lester, H.A.1
Krouse, M.E.2
Nass, M.M.3
Wassermann, N.H.4
Erlanger, B.F.5
-
41
-
-
33645218213
-
Allosteric control of an ionotropic glutamate receptor with an optical switch
-
Volgraf, M., Gorostiza, P., Numano, R., Kramer, R. H., Isacoff, E. Y., and Trauner, D. (2006) Allosteric control of an ionotropic glutamate receptor with an optical switch. Nat. Chem. Biol. 2, 47-52.
-
(2006)
Nat. Chem. Biol
, vol.2
, pp. 47-52
-
-
Volgraf, M.1
Gorostiza, P.2
Numano, R.3
Kramer, R.H.4
Isacoff, E.Y.5
Trauner, D.6
-
42
-
-
12344309164
-
Light-activated ion channels for remote control of neuronal firing
-
Banghart, M., Borges, K., Isacoff, E., Trauner, D., and Kramer, R. H. (2004) Light-activated ion channels for remote control of neuronal firing. Nat. Neurosci. 7, 1381-1386.
-
(2004)
Nat. Neurosci
, vol.7
, pp. 1381-1386
-
-
Banghart, M.1
Borges, K.2
Isacoff, E.3
Trauner, D.4
Kramer, R.H.5
-
43
-
-
0030471462
-
-
Lien, L., Jaikaran, D. C. J., Zhang, Z., and Woolley, G. A. (1996) Photomodulated Blocking of Gramicidin Ion Channels. J. Am. Chem. Soc. 118, 12222-12223.
-
Lien, L., Jaikaran, D. C. J., Zhang, Z., and Woolley, G. A. (1996) Photomodulated Blocking of Gramicidin Ion Channels. J. Am. Chem. Soc. 118, 12222-12223.
-
-
-
-
44
-
-
0032321487
-
Substituted-cysteine accessibility method
-
Karlin, A., and Akabas, M. H. (1998) Substituted-cysteine accessibility method. Methods Enzymol. 293, 123-145.
-
(1998)
Methods Enzymol
, vol.293
, pp. 123-145
-
-
Karlin, A.1
Akabas, M.H.2
-
45
-
-
41449113929
-
Photochemical control of endogenous ion channels and cellular excitability
-
Fortin, D. L., Banghart, M. R., Dunn, T. W., Borges, K., Wagenaar, D. A., Gaudry, Q., Karakossian, M. H., Otis, T. S., Kristan, W. B., Trauner, D., and Kramer, R. H. (2008) Photochemical control of endogenous ion channels and cellular excitability. Nat. Methods 5, 331-338.
-
(2008)
Nat. Methods
, vol.5
, pp. 331-338
-
-
Fortin, D.L.1
Banghart, M.R.2
Dunn, T.W.3
Borges, K.4
Wagenaar, D.A.5
Gaudry, Q.6
Karakossian, M.H.7
Otis, T.S.8
Kristan, W.B.9
Trauner, D.10
Kramer, R.H.11
-
46
-
-
0024968835
-
A general method for site-specific incorporation of unnatural amino acids into proteins
-
Noren, C. J., Anthony-Cahill, S. J., Griffith, M. C., and Schultz, P. G. (1989) A general method for site-specific incorporation of unnatural amino acids into proteins. Science 244, 182-188.
-
(1989)
Science
, vol.244
, pp. 182-188
-
-
Noren, C.J.1
Anthony-Cahill, S.J.2
Griffith, M.C.3
Schultz, P.G.4
-
47
-
-
0032311418
-
In vivo incorporation of unnatural amino acids into ion channels in Xenopus oocyte expression system
-
Nowak, M. W., Gallivan, J. P., Silverman, S. K., Labarca, C. G., Dougherty, D. A., and Lester, H. A. (1998) In vivo incorporation of unnatural amino acids into ion channels in Xenopus oocyte expression system. Methods Enzymol. 293, 504-529.
-
(1998)
Methods Enzymol
, vol.293
, pp. 504-529
-
-
Nowak, M.W.1
Gallivan, J.P.2
Silverman, S.K.3
Labarca, C.G.4
Dougherty, D.A.5
Lester, H.A.6
-
48
-
-
0030923523
-
Site-specific, photochemical proteolysis applied to ion channels in vivo
-
England, P. M., Lester, H. A., Davidson, N., and Dougherty, D. A. (1997) Site-specific, photochemical proteolysis applied to ion channels in vivo. Proc. Natl. Acad. Sci. U.S.A. 94, 11025-11030.
-
(1997)
Proc. Natl. Acad. Sci. U.S.A
, vol.94
, pp. 11025-11030
-
-
England, P.M.1
Lester, H.A.2
Davidson, N.3
Dougherty, D.A.4
-
50
-
-
0037204951
-
Probing protein electrostatics with a synthetic fluorescent amino acid
-
Cohen, B. E., McAnaney, T. B., Park, E. S., Jan, Y. N., Boxer, S. G., and Jan, L. Y. (2002) Probing protein electrostatics with a synthetic fluorescent amino acid. Science 296, 1700-1703.
-
(2002)
Science
, vol.296
, pp. 1700-1703
-
-
Cohen, B.E.1
McAnaney, T.B.2
Park, E.S.3
Jan, Y.N.4
Boxer, S.G.5
Jan, L.Y.6
-
51
-
-
4243468938
-
The Cation-π Interaction
-
Ma, J. C., and Dougherty, D. A. (1997) The Cation-π Interaction. Chem. Rev. 97, 1303-1324.
-
(1997)
Chem. Rev
, vol.97
, pp. 1303-1324
-
-
Ma, J.C.1
Dougherty, D.A.2
-
52
-
-
0035113738
-
The tethered agonist approach to mapping ion channel proteins: Toward a structural model for the agonist binding site of the nicotinic acetylcholine receptor
-
Li, L., Zhong, W., Zacharias, N., Gibbs, C., Lester, H. A., and Dougherty, D. A. (2001) The tethered agonist approach to mapping ion channel proteins: Toward a structural model for the agonist binding site of the nicotinic acetylcholine receptor. Chem. Biol. 8, 47-58.
-
(2001)
Chem. Biol
, vol.8
, pp. 47-58
-
-
Li, L.1
Zhong, W.2
Zacharias, N.3
Gibbs, C.4
Lester, H.A.5
Dougherty, D.A.6
-
53
-
-
5644237713
-
Tyrosine residues that control binding and gating in the 5-hydroxytryptamine3 receptor revealed by unnatural amino acid mutagenesis
-
Beene, D. L., Price, K. L., Lester, H. A., Dougherty, D. A., and Lummis, S. C. (2004) Tyrosine residues that control binding and gating in the 5-hydroxytryptamine3 receptor revealed by unnatural amino acid mutagenesis. J. Neurosci. 24, 9097-9104.
-
(2004)
J. Neurosci
, vol.24
, pp. 9097-9104
-
-
Beene, D.L.1
Price, K.L.2
Lester, H.A.3
Dougherty, D.A.4
Lummis, S.C.5
-
54
-
-
38349142833
-
5-Fluorotryptamine is a partial agonist at 5-HT3 receptors, and reveals that size and electronegativity at the 5 position of tryptamine are critical for efficient receptor function
-
Bower, K. S., Price, K. L., Sturdee, L. E., Dayrell, M., Dougherty, D. A., and Lummis, S. C. (2008) 5-Fluorotryptamine is a partial agonist at 5-HT3 receptors, and reveals that size and electronegativity at the 5 position of tryptamine are critical for efficient receptor function. Eur. J. Pharmacol. 580, 291-297.
-
(2008)
Eur. J. Pharmacol
, vol.580
, pp. 291-297
-
-
Bower, K.S.1
Price, K.L.2
Sturdee, L.E.3
Dayrell, M.4
Dougherty, D.A.5
Lummis, S.C.6
-
55
-
-
25144465496
-
A cation-π binding interaction with a tyrosine in the binding site of the GABAC receptor
-
Lummis, S. C. D. L. B., Harrison, N. J., Lester, H. A., and Dougherty, D. A. (2005) A cation-π binding interaction with a tyrosine in the binding site of the GABAC receptor. Chem. Biol. 12, 993-997.
-
(2005)
Chem. Biol
, vol.12
, pp. 993-997
-
-
Lummis, S.C.D.L.B.1
Harrison, N.J.2
Lester, H.A.3
Dougherty, D.A.4
-
56
-
-
33751517798
-
-
2+ blockade site of an N-methyl-D-aspartate (NMDA) receptor with unnatural amino acid mutagenesis. ACS Chem. Biol. 1, 227-234.
-
2+ blockade site of an N-methyl-D-aspartate (NMDA) receptor with unnatural amino acid mutagenesis. ACS Chem. Biol. 1, 227-234.
-
-
-
-
57
-
-
58149166932
-
A cation-π interaction in the binding site of the glycine receptor is mediated by a phenylalanine residue
-
Pless, S. A., Millen, K. S., Hanek, A. P., Lynch, J. W., Lester, H. A., Lummis, S. C., and Dougherty, D. A. (2008) A cation-π interaction in the binding site of the glycine receptor is mediated by a phenylalanine residue. J. Neurosci. 28, 10937-10942.
-
(2008)
J. Neurosci
, vol.28
, pp. 10937-10942
-
-
Pless, S.A.1
Millen, K.S.2
Hanek, A.P.3
Lynch, J.W.4
Lester, H.A.5
Lummis, S.C.6
Dougherty, D.A.7
-
58
-
-
37849001772
-
Electrostatic contributions of aromatic residues in the local anesthetic receptor of voltage-gated sodium channels
-
Ahern, C. A., Eastwood, A. L., Dougherty, D. A., and Horn, R. (2008) Electrostatic contributions of aromatic residues in the local anesthetic receptor of voltage-gated sodium channels. Circ. Res. 102, 86-94.
-
(2008)
Circ. Res
, vol.102
, pp. 86-94
-
-
Ahern, C.A.1
Eastwood, A.L.2
Dougherty, D.A.3
Horn, R.4
-
59
-
-
34848876603
-
Calcium block of single sodium channels: Role of a pore-lining aromatic residue
-
Santarelli, V. P., Eastwood, A. L., Dougherty, D. A., Ahern, C. A., and Horn, R. (2007) Calcium block of single sodium channels: Role of a pore-lining aromatic residue. Biophys. J. 93, 2341-2349.
-
(2007)
Biophys. J
, vol.93
, pp. 2341-2349
-
-
Santarelli, V.P.1
Eastwood, A.L.2
Dougherty, D.A.3
Ahern, C.A.4
Horn, R.5
-
60
-
-
34247267099
-
A cation-π interaction discriminates among sodium channels that are either sensitive or resistant to tetrodotoxin block
-
Santarelli, V. P., Eastwood, A. L., Dougherty, D. A., Horn, R., and Ahern, C. A. (2007) A cation-π interaction discriminates among sodium channels that are either sensitive or resistant to tetrodotoxin block. J. Biol. Chem. 282, 8044-8051.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 8044-8051
-
-
Santarelli, V.P.1
Eastwood, A.L.2
Dougherty, D.A.3
Horn, R.4
Ahern, C.A.5
-
61
-
-
33751517446
-
A cation-π interaction between extracellular TEA and an aromatic residue in potassium channels
-
Ahern, C. A., Eastwood, A. L., Lester, H. A., Dougherty, D. A., and Horn, R. (2006) A cation-π interaction between extracellular TEA and an aromatic residue in potassium channels. J. Gen. Physiol. 128, 649-657.
-
(2006)
J. Gen. Physiol
, vol.128
, pp. 649-657
-
-
Ahern, C.A.1
Eastwood, A.L.2
Lester, H.A.3
Dougherty, D.A.4
Horn, R.5
-
63
-
-
34547502435
-
Genetically encoding unnatural amino acids for cellular and neuronal studies
-
Wang, W., Takimoto, J. K., Louie, G. V., Baiga, T. J., Noel, J. P., Lee, K. F., Slesinger, P. A., and Wang, L. (2007) Genetically encoding unnatural amino acids for cellular and neuronal studies. Nat. Neurosci. 10, 1063-1072.
-
(2007)
Nat. Neurosci
, vol.10
, pp. 1063-1072
-
-
Wang, W.1
Takimoto, J.K.2
Louie, G.V.3
Baiga, T.J.4
Noel, J.P.5
Lee, K.F.6
Slesinger, P.A.7
Wang, L.8
-
64
-
-
34548602702
-
-
Xie, J., Supekova, L., and Schultz, P. G. (2007) A genetically encoded metabolically stable analogue of phosphotyrosine in Escherichia coli. ACS Chem. Biol. 2, 474-478.
-
Xie, J., Supekova, L., and Schultz, P. G. (2007) A genetically encoded metabolically stable analogue of phosphotyrosine in Escherichia coli. ACS Chem. Biol. 2, 474-478.
-
-
-
-
65
-
-
33745946445
-
A genetically encoded fluorescent amino acid
-
Wang, J., Xie, J., and Schultz, P. G. (2006) A genetically encoded fluorescent amino acid. J. Am. Chem. Soc. 128, 8738-8739.
-
(2006)
J. Am. Chem. Soc
, vol.128
, pp. 8738-8739
-
-
Wang, J.1
Xie, J.2
Schultz, P.G.3
-
66
-
-
33847648384
-
Genetic incorporation of unnatural amino acids into proteins in mammalian cells
-
Liu, W., Brock, A., Chen, S., and Schultz, P. G. (2007) Genetic incorporation of unnatural amino acids into proteins in mammalian cells. Nat. Methods 4, 239-244.
-
(2007)
Nat. Methods
, vol.4
, pp. 239-244
-
-
Liu, W.1
Brock, A.2
Chen, S.3
Schultz, P.G.4
-
67
-
-
0032499752
-
Expressed protein ligation: A general method for protein engineering
-
Muir, T. W., Sondhi, D., and Cole, P. A. (1998) Expressed protein ligation: A general method for protein engineering. Proc. Natl. Acad. Sci. U.S.A. 95, 6705-6710.
-
(1998)
Proc. Natl. Acad. Sci. U.S.A
, vol.95
, pp. 6705-6710
-
-
Muir, T.W.1
Sondhi, D.2
Cole, P.A.3
-
68
-
-
33744529377
-
Protein ligation: An enabling technology for the biophysical analysis of proteins
-
Muralidharan, V., and Muir, T. W. (2006) Protein ligation: An enabling technology for the biophysical analysis of proteins. Nat. Methods 3, 429-438.
-
(2006)
Nat. Methods
, vol.3
, pp. 429-438
-
-
Muralidharan, V.1
Muir, T.W.2
-
71
-
-
0037036754
-
Semisynthesis and folding of the potassium channel KcsA
-
Valiyaveetil, F. I., MacKinnon, R., and Muir, T. W. (2002) Semisynthesis and folding of the potassium channel KcsA. J. Am. Chem. Soc. 124, 9113-9120.
-
(2002)
J. Am. Chem. Soc
, vol.124
, pp. 9113-9120
-
-
Valiyaveetil, F.I.1
MacKinnon, R.2
Muir, T.W.3
-
72
-
-
33748360106
-
Structural and functional consequences of an amide-to-ester substitution in the selectivity filter of a potassium channel
-
Valiyaveetil, F. I., Sekedat, M., MacKinnon, R., and Muir, T. W. (2006) Structural and functional consequences of an amide-to-ester substitution in the selectivity filter of a potassium channel. J. Am. Chem. Soc. 128, 11591-11599.
-
(2006)
J. Am. Chem. Soc
, vol.128
, pp. 11591-11599
-
-
Valiyaveetil, F.I.1
Sekedat, M.2
MacKinnon, R.3
Muir, T.W.4
-
74
-
-
0036014776
-
Conformations of amino acids in proteins
-
Hovmoller, S., Zhou, T., and Ohlson, T. (2002) Conformations of amino acids in proteins. Acta Crystallogr. D58, 768-776.
-
(2002)
Acta Crystallogr
, vol.D58
, pp. 768-776
-
-
Hovmoller, S.1
Zhou, T.2
Ohlson, T.3
-
75
-
-
0032313490
-
Identification of ion channel-associated proteins using the yeast two-hybrid system
-
Niethammer, M., and Sheng, M. (1998) Identification of ion channel-associated proteins using the yeast two-hybrid system. Methods Enzvmol. 293, 104-122.
-
(1998)
Methods Enzvmol
, vol.293
, pp. 104-122
-
-
Niethammer, M.1
Sheng, M.2
-
76
-
-
0024042922
-
TRK1 encodes a plasma membrane protein required for high-affinity potassium transport in Saccharomyces cereVisiae
-
Gaber, R. F., Styles, C. A., and Fink, G R. (1988) TRK1 encodes a plasma membrane protein required for high-affinity potassium transport in Saccharomyces cereVisiae. Mol. Cell. Biol. 8, 2848-2859.
-
(1988)
Mol. Cell. Biol
, vol.8
, pp. 2848-2859
-
-
Gaber, R.F.1
Styles, C.A.2
Fink, G.R.3
-
78
-
-
0032313519
-
Studying ion channels using yeast genetics
-
Nakamura, R. L., and Gaber, R. F. (1998) Studying ion channels using yeast genetics. Methods Enzymol. 293, 89-104.
-
(1998)
Methods Enzymol
, vol.293
, pp. 89-104
-
-
Nakamura, R.L.1
Gaber, R.F.2
-
79
-
-
0026597932
-
Functional expression of a probable Arabidopsis thaliana potassium channel in Saccharomyces cereVisiae
-
Anderson, J. A., Huprikar, S. S., Kochian, L. V., Lucas, W. J., and Gaber, R. F. (1992) Functional expression of a probable Arabidopsis thaliana potassium channel in Saccharomyces cereVisiae. Proc. Natl. Acad. Sci. U.S.A. 89, 3736-3740.
-
(1992)
Proc. Natl. Acad. Sci. U.S.A
, vol.89
, pp. 3736-3740
-
-
Anderson, J.A.1
Huprikar, S.S.2
Kochian, L.V.3
Lucas, W.J.4
Gaber, R.F.5
-
80
-
-
0033582936
-
Transmembrane structure of an inwardly rectifying potassium channel
-
Minor, D. L., Jr., Masseling, S. J., Jan, Y. N., and Jan, L. Y. (1999) Transmembrane structure of an inwardly rectifying potassium channel. Cell 96, 879-891.
-
(1999)
Cell
, vol.96
, pp. 879-891
-
-
Minor Jr., D.L.1
Masseling, S.J.2
Jan, Y.N.3
Jan, L.Y.4
-
82
-
-
0037167878
-
Voltagesensing mechanism is conserved among ion channels gated by opposite voltages
-
Mannikko, R., Elinder, F., and Larsson, H. P. (2002) Voltagesensing mechanism is conserved among ion channels gated by opposite voltages. Nature 419, 837-841.
-
(2002)
Nature
, vol.419
, pp. 837-841
-
-
Mannikko, R.1
Elinder, F.2
Larsson, H.P.3
-
83
-
-
0141954276
-
Molecular coupling between voltage sensor and pore opening in the Arabidopsis inward rectifier K+ channel KAT1
-
Latorre, R., Olcese, R., Basso, C., Gonzalez, C., Munoz, F., Cosmelli, D., and Alvarez, O. (2003) Molecular coupling between voltage sensor and pore opening in the Arabidopsis inward rectifier K+ channel KAT1. J. Gen. Physiol. 122, 459-469.
-
(2003)
J. Gen. Physiol
, vol.122
, pp. 459-469
-
-
Latorre, R.1
Olcese, R.2
Basso, C.3
Gonzalez, C.4
Munoz, F.5
Cosmelli, D.6
Alvarez, O.7
-
84
-
-
23044489633
-
The S4 voltage sensor packs against the pore domain in the KAT1 voltagegated potassium channel
-
Lai, H. C., Grabe, M., Jan, Y. N., and Jan, L. Y. (2005) The S4 voltage sensor packs against the pore domain in the KAT1 voltagegated potassium channel. Neuron 47, 395-406.
-
(2005)
Neuron
, vol.47
, pp. 395-406
-
-
Lai, H.C.1
Grabe, M.2
Jan, Y.N.3
Jan, L.Y.4
-
85
-
-
33846694346
-
Structure prediction for the down state of a potassium channel voltage sensor
-
Grabe, M., Lai, H. C., Jain, M., Jan, Y. N., and Jan, L. Y. (2007) Structure prediction for the down state of a potassium channel voltage sensor. Nature 445, 550-553.
-
(2007)
Nature
, vol.445
, pp. 550-553
-
-
Grabe, M.1
Lai, H.C.2
Jain, M.3
Jan, Y.N.4
Jan, L.Y.5
-
86
-
-
0026594721
-
The size of gating charge in wild-type and mutant Shaker potassium channels
-
Schoppa, N. E., McCormack, K., Tanouye, M. A., and Sigworth, F. J. (1992) The size of gating charge in wild-type and mutant Shaker potassium channels. Science 255, 1712-1715.
-
(1992)
Science
, vol.255
, pp. 1712-1715
-
-
Schoppa, N.E.1
McCormack, K.2
Tanouye, M.A.3
Sigworth, F.J.4
-
87
-
-
0030059224
-
Direct physical measure of conformational rearrangement underlying potassium channel gating
-
Mannuzzu, L. M., Moronne, M. M., and Isacoff, E. Y. (1996) Direct physical measure of conformational rearrangement underlying potassium channel gating. Science 271, 213-216.
-
(1996)
Science
, vol.271
, pp. 213-216
-
-
Mannuzzu, L.M.1
Moronne, M.M.2
Isacoff, E.Y.3
-
89
-
-
38749119750
-
Activation of Kv7 (KCNQ) voltage-gated potassium channels by synthetic compounds
-
Xiong, Q., Gao, Z., Wang, W., and Li, M. (2008) Activation of Kv7 (KCNQ) voltage-gated potassium channels by synthetic compounds. Trends Pharmacol. Sci. 29, 99-107.
-
(2008)
Trends Pharmacol. Sci
, vol.29
, pp. 99-107
-
-
Xiong, Q.1
Gao, Z.2
Wang, W.3
Li, M.4
-
90
-
-
34247202495
-
Zinc pyrithione-mediated activation of voltage-gated KCNQ potassium channels rescues epileptogenic mutants
-
Xiong, Q., Sun, H., and Li, M. (2007) Zinc pyrithione-mediated activation of voltage-gated KCNQ potassium channels rescues epileptogenic mutants. Nat. Chem. Biol. 3, 287-296.
-
(2007)
Nat. Chem. Biol
, vol.3
, pp. 287-296
-
-
Xiong, Q.1
Sun, H.2
Li, M.3
-
91
-
-
10244237790
-
Nonradioactive rubidium ion efflux assay and its applications in drug discovery and development
-
Terstappen, G C. (2004) Nonradioactive rubidium ion efflux assay and its applications in drug discovery and development. Assay Drug DeV. Technol. 2, 553-559.
-
(2004)
Assay Drug DeV. Technol
, vol.2
, pp. 553-559
-
-
Terstappen, G.C.1
-
92
-
-
32844461535
-
Identification of novel Kv1.3 blockers using a fluorescent cell-based ion channel assay
-
Slack, M., Kirchhoff, C., Moller, C., Winkler, D., and Netzer, R. (2006) Identification of novel Kv1.3 blockers using a fluorescent cell-based ion channel assay. J. Biomol. Screening 11, 57-64.
-
(2006)
J. Biomol. Screening
, vol.11
, pp. 57-64
-
-
Slack, M.1
Kirchhoff, C.2
Moller, C.3
Winkler, D.4
Netzer, R.5
-
93
-
-
53049101647
-
Desensitization of chemical activation by auxiliary subunits: Convergence of molecular determinants critical for augmenting KCNQ1 potassium channels
-
Gao, Z., Xiong, Q., Sun, H., and Li, M. (2008) Desensitization of chemical activation by auxiliary subunits: Convergence of molecular determinants critical for augmenting KCNQ1 potassium channels. J. Biol. Chem. 283, 22649-22658.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 22649-22658
-
-
Gao, Z.1
Xiong, Q.2
Sun, H.3
Li, M.4
|