Light-activated ion channels for remote control of neuronal firing

Nature Neuroscience

Volumn 7, Issue 12, 2004, Pages 1381-1386

  Banghart, Matthew ^a   Borges, Katharine ^a   Isacoff, Ehud ^a   Trauner, Dirk ^a   Kramer, Richard H ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZOBENZENE; ION CHANNEL; POTASSIUM CHANNEL;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; EMBRYO; HIPPOCAMPUS; LIGHT; NERVE CELL DEGENERATION; NERVE CONDUCTION; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; CELL CULTURE; CHANNEL GATING; CHEMISTRY; COMPARATIVE STUDY; FEMALE; METHODOLOGY; NERVE CELL; PHOTOSTIMULATION; PHYSIOLOGY; SPRAGUE DAWLEY RAT; XENOPUS LAEVIS;

ACTION POTENTIALS; ANIMALS; CELLS, CULTURED; FEMALE; HIPPOCAMPUS; ION CHANNEL GATING; ION CHANNELS; NEURONS; PHOTIC STIMULATION; RATS; RATS, SPRAGUE-DAWLEY; XENOPUS LAEVIS;

EID: 12344309164     PISSN: 10976256     EISSN: None     Source Type: Journal    
DOI: 10.1038/nn1356     Document Type: Article

References (31)

1. Nerbonne, J.M. Caged compounds: tools for illuminating neuronal responses and connections. Curr. Opin. Neurobiol. 6, 379-386 (1996).
2. James, D.A., Burns, D.C. & Woolley, G.A. Kinetic characterization of ribonuclease S mutants containing photoisomerizable phenylazophenylalanine residues. Protein Eng. 14, 983-991 (2001).
3. Flint, D.G., Kumita, J.R., Smart, O.S. & Woolley, G.A. Using an azobenzene cross-linker to either increase or decrease peptide helix content upon trans-to-cis photoisomerization. Chem. Biol. 9, 391-397 (2002).
4. Lester, H.A., Krouse, M.E., Nass, M.M., Wassermann, N.H. & Erlanger, B.F. A covalently bound photoisomerizable agonist: comparison with reversibly bound agonists at Electrophorus electroplaques. J. Gen. Physiol. 75, 207-232 (1980).
5. Katz, L.C. & Dalva, M.B. Scanning laser photostimulation: a new approach for analyzing brain circuits. J. Neurosci. Methods 54, 205-218 (1994).
6. Callaway, E.M. Caged neurotransmitters. Shedding light on neural circuits. Curr. Biol. 4, 1010-1012 (1994).
7. Nitabach, M., Blau, J. & Holmes, T. Electrical silencing of Drosophila pacemaker neurons stops the free-running circadian clock. Cell 109, 485-495 (2002).
8. Johns, D., Marx, R., Mains, R., O'Rourke, B. & Marban, E. Inducible genetic suppression of neuronal excitability. J. Neurosci. 19, 1691-1697 (1999).
9. + channel. Neuron 31, 699-711 (2001).
10. Lechner, H., Lein, E. & Callaway, E. A genetic method for selective and quickly reversible silencing of mammalian neurons. J. Neurosci. 22, 5287-5290 (2002).
11. Slimko, E., McKinney, S., Anderson, D., Davidson, N. & Lester, H. Selective electrical silencing of mammalian neurons in vitro by the use of invertebrate ligand-gated chloride channels. J. Neurosci. 22, 7373-7379 (2002).
12. Zemelman, B.V., Lee, G.A., Ng, M. & Miesenbock, G. Selective photostimulation of genetically chARGed neurons. Neuron 33, 15-22 (2002).
13. Sigworth, F. Voltage gating of ion channels. Q. Rev. Biophys. 27, 1-40 (1994).
14. Yellen, G. The voltage-gated potassium channels and their relatives. Nature 419, 35-42 (2002).
15. + channels. Science 250, 276-279 (1990).
16. Heginbotham, L. & MacKinnon, R. The aromatic binding site for tetraethylammonium ion on potassium channels. Neuron 8, 483-491 (1992).
17. + channel. Nat. Struct. Biol. 7, 309-311 (2000).
18. + conduction and selectivity. Science 280, 69-77 (1998).
19. + channel. Nature 423, 33-41 (2003).
20. Knoll, H. Photoisomerism of azobenzenes. in CRC Handbook of Organic Photochemistry and Photobiology edn. 2 (eds. Horspool, W. & Lenci, F.) 89.1-89.16 (CRC Press, Boca Raton, Florida, USA, 2004).
21. + channels. Proc. Natl. Acad. Sci. USA 88, 5092-5095 (1991).
22. Hoshi, T., Zagotta, W. & Aldrich, R. Biophysical and molecular mechanisms of Shaker potassium channel inactivation. Science 250, 533-538 (1990).
23. Lopez-Barneo, J., Hoshi, T., Heinemann, S. & Aldrich, R. Effects of external cations and mutations in the pore region on C-type inactivation of Shaker potassium channels. Receptors Channels 1, 61-71 (1993).
24. + channels. Neuron 7, 327-336 (1991).
25. + channels. J. Gen. Physiol. 120, 203-216 (2002).
26. Griffin, B.A., Adams, S.R. & Tsien, R.Y. Specific covalent labeling of recombinant protein molecules inside live cells. Science 281, 269-272 (1998).
27. Sutherland, M.L. et al. Overexpression of a Shaker-type potassium channel in mammalian central nervous system dysregulates native potassium channel gene expression. Proc. Natl. Acad. Sci. USA 96, 2451-2455 (1999).
28. Gu, C., Jan, Y.N. & Jan, L.Y. A conserved domain in axonal targeting of Kv1 (Shaker) voltage-gated potassium channels. Science 301, 646-649 (2003).
29. + channel expression in primary cell cultures mediated by vaccinia virus. FEBS Lett. 278, 229-233 (1991).
30. Djurisic, M. et al. Optical monitoring of neural activity using voltage-sensitive dyes. Methods Enzymol. 361, 423-451 (2003).
31. Jiang, Y. et al. The open pore conformation of potassium channels. Nature 417, 523-526 (2002).