-
1
-
-
0036691491
-
A genome-wide screen for linkage in Nordic sib-pairs with multiple sclerosis
-
Akesson E, Oturai A, Berg J, Fredrikson S, Andersen O, Harbo HF, et al. A genome-wide screen for linkage in Nordic sib-pairs with multiple sclerosis. Genes Immun 2002; 3: 279-85.
-
(2002)
Genes Immun
, vol.3
, pp. 279-285
-
-
Akesson, E.1
Oturai, A.2
Berg, J.3
Fredrikson, S.4
Andersen, O.5
Harbo, H.F.6
-
2
-
-
18544382074
-
The MHC haplotype project: A resource for HLA-linked association studies
-
Allcock RJ, Atrazhev AM, Beck S, de Jong PJ, Elliott JF, Forbes S, et al. The MHC haplotype project: a resource for HLA-linked association studies. Tissue Antigens 2002; 59: 520-1.
-
(2002)
Tissue Antigens
, vol.59
, pp. 520-521
-
-
Allcock, R.J.1
Atrazhev, A.M.2
Beck, S.3
de Jong, P.J.4
Elliott, J.F.5
Forbes, S.6
-
4
-
-
0042914324
-
A genome screen for linkage in Australian sibling-pairs with multiple sclerosis
-
Ban M, Stewart GJ, Bennetts BH, Heard R, Simmons R, Maranian M, et al. A genome screen for linkage in Australian sibling-pairs with multiple sclerosis. Genes Immun 2002; 3: 464-9.
-
(2002)
Genes Immun
, vol.3
, pp. 464-469
-
-
Ban, M.1
Stewart, G.J.2
Bennetts, B.H.3
Heard, R.4
Simmons, R.5
Maranian, M.6
-
5
-
-
33748740746
-
Heterogeneity at the HLA-DRB1 locus and risk for multiple sclerosis
-
Barcellos LF, Sawcer S, Ramsay PP, Baranzini SE, Thomson G, Briggs F, et al. Heterogeneity at the HLA-DRB1 locus and risk for multiple sclerosis. Hum Mol Genet 2006; 15: 2813-24.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 2813-2824
-
-
Barcellos, L.F.1
Sawcer, S.2
Ramsay, P.P.3
Baranzini, S.E.4
Thomson, G.5
Briggs, F.6
-
6
-
-
18044401149
-
A genome screen for multiple sclerosis in Italian families
-
Broadley S, Sawcer S, D'Alfonso S, Hensiek A, Coraddu F, Gray J, et al. A genome screen for multiple sclerosis in Italian families. Genes Immun 2001; 2: 205-10.
-
(2001)
Genes Immun
, vol.2
, pp. 205-210
-
-
Broadley, S.1
Sawcer, S.2
D'Alfonso, S.3
Hensiek, A.4
Coraddu, F.5
Gray, J.6
-
7
-
-
35748981184
-
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants
-
Burton PR, Clayton DG, Cardon LR, Craddock N, Deloukas P, Duncanson A, et al. Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat Genet 2007; 39: 1329-37.
-
(2007)
Nat Genet
, vol.39
, pp. 1329-1337
-
-
Burton, P.R.1
Clayton, D.G.2
Cardon, L.R.3
Craddock, N.4
Deloukas, P.5
Duncanson, A.6
-
8
-
-
33646712168
-
APOE epsilon variation in multiple sclerosis susceptibility and disease severity: Some answers
-
Burwick RM, Ramsay PP, Haines JL, Hauser SL, Oksenberg JR, Pericak-Vance MA, et al. APOE epsilon variation in multiple sclerosis susceptibility and disease severity: some answers. Neurology 2006; 66: 1373-83.
-
(2006)
Neurology
, vol.66
, pp. 1373-1383
-
-
Burwick, R.M.1
Ramsay, P.P.2
Haines, J.L.3
Hauser, S.L.4
Oksenberg, J.R.5
Pericak-Vance, M.A.6
-
9
-
-
0035257236
-
Association study designs for complex diseases
-
Cardon LR, Bell JI. Association study designs for complex diseases. Nat Rev Genet 2001; 2: 91-9.
-
(2001)
Nat Rev Genet
, vol.2
, pp. 91-99
-
-
Cardon, L.R.1
Bell, J.I.2
-
10
-
-
0030903014
-
Risks of multiple sclerosis in relatives of patients in Flanders, Belgium
-
Carton H, Vlietinck R, Debruyne J, De Keyser J, D'Hooghe MB, Loos R, et al. Risks of multiple sclerosis in relatives of patients in Flanders, Belgium. J Neurol Neurosurg Psychiatry 1997; 62: 329-33.
-
(1997)
J Neurol Neurosurg Psychiatry
, vol.62
, pp. 329-333
-
-
Carton, H.1
Vlietinck, R.2
Debruyne, J.3
De Keyser, J.4
D'Hooghe, M.B.5
Loos, R.6
-
11
-
-
27644546712
-
Population structure, differential bias and genomic control in a large-scale, case-control association study
-
Clayton DG, Walker NM, Smyth DJ, Pask R, Cooper JD, Maier LM, et al. Population structure, differential bias and genomic control in a large-scale, case-control association study. Nat Genet 2005; 37: 1243-6.
-
(2005)
Nat Genet
, vol.37
, pp. 1243-1246
-
-
Clayton, D.G.1
Walker, N.M.2
Smyth, D.J.3
Pask, R.4
Cooper, J.D.5
Maier, L.M.6
-
12
-
-
0021341456
-
Class II HLA-DC beta-chain DNA restriction fragments differentiate among HLA-DR2 individuals in insulin-dependent diabetes and multiple sclerosis
-
Cohen D, Cohen O, Marcadet A, Massart C, Lathrop M, Deschamps I, et al. Class II HLA-DC beta-chain DNA restriction fragments differentiate among HLA-DR2 individuals in insulin-dependent diabetes and multiple sclerosis. Proc Natl Acad Sci USA 1984; 81: 1774-8.
-
(1984)
Proc Natl Acad Sci USA
, vol.81
, pp. 1774-1778
-
-
Cohen, D.1
Cohen, O.2
Marcadet, A.3
Massart, C.4
Lathrop, M.5
Deschamps, I.6
-
13
-
-
33244488712
-
Making progress on the natural history of multiple sclerosis
-
Compston A. Making progress on the natural history of multiple sclerosis. Brain 2006; 129: 561-3.
-
(2006)
Brain
, vol.129
, pp. 561-563
-
-
Compston, A.1
-
14
-
-
0037029424
-
Multiple sclerosis
-
Compston A, Coles A. Multiple sclerosis. Lancet 2002; 359: 1221-31.
-
(2002)
Lancet
, vol.359
, pp. 1221-1231
-
-
Compston, A.1
Coles, A.2
-
15
-
-
84882504897
-
-
London: Churchill Livingstone;
-
Compston A, Confavreux C, Lassmann H, McDonald I, Miller D, Noseworthy J, et al. McAlpine's multiple sclerosis. London: Churchill Livingstone; 2006; 113-81.
-
(2006)
McAlpine's multiple sclerosis
, pp. 113-181
-
-
Compston, A.1
Confavreux, C.2
Lassmann, H.3
McDonald, I.4
Miller, D.5
Noseworthy, J.6
-
16
-
-
0017109389
-
B-lymphocyte alloantigens associated with multiple sclerosis
-
Compston DA, Batchelor JR, McDonald WI. B-lymphocyte alloantigens associated with multiple sclerosis. Lancet 1976; 2: 1261-5.
-
(1976)
Lancet
, vol.2
, pp. 1261-1265
-
-
Compston, D.A.1
Batchelor, J.R.2
McDonald, W.I.3
-
17
-
-
33244469927
-
Age at disability milestones in multiple sclerosis
-
Confavreux C, Vukusic S. Age at disability milestones in multiple sclerosis. Brain 2006a; 129: 595-605.
-
(2006)
Brain
, vol.129
, pp. 595-605
-
-
Confavreux, C.1
Vukusic, S.2
-
18
-
-
33244466021
-
Natural history of multiple sclerosis: A unifying concept
-
Confavreux C, Vukusic S. Natural history of multiple sclerosis: a unifying concept. Brain 2006b; 129: 606-16.
-
(2006)
Brain
, vol.129
, pp. 606-616
-
-
Confavreux, C.1
Vukusic, S.2
-
19
-
-
17944373274
-
A genome screen for multiple sclerosis in Sardinian multiplex families
-
Coraddu F, Sawcer S, D'Alfonso S, Lai M, Hensiek A, Solla E, et al. A genome screen for multiple sclerosis in Sardinian multiplex families. Eur J Hum Genet 2001; 9: 621-6.
-
(2001)
Eur J Hum Genet
, vol.9
, pp. 621-626
-
-
Coraddu, F.1
Sawcer, S.2
D'Alfonso, S.3
Lai, M.4
Hensiek, A.5
Solla, E.6
-
20
-
-
27944439639
-
Lymphocyte homeostasis following therapeutic lymphocyte depletion in multiple sclerosis
-
Cox AL, Thompson SA, Jones JL, Robertson VH, Hale G, Waldmann H, et al. Lymphocyte homeostasis following therapeutic lymphocyte depletion in multiple sclerosis. Eur J Immunol 2005; 35: 3332-42.
-
(2005)
Eur J Immunol
, vol.35
, pp. 3332-3342
-
-
Cox, A.L.1
Thompson, S.A.2
Jones, J.L.3
Robertson, V.H.4
Hale, G.5
Waldmann, H.6
-
21
-
-
33749137515
-
A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC
-
de Bakker PI, McVean G, Sabeti PC, Miretti MM, Green T, Marchini J, et al. A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC. Nat Genet 2006; 38: 1166-72.
-
(2006)
Nat Genet
, vol.38
, pp. 1166-1172
-
-
de Bakker, P.I.1
McVean, G.2
Sabeti, P.C.3
Miretti, M.M.4
Green, T.5
Marchini, J.6
-
22
-
-
0037183507
-
Evidence for additional genetic risk indicators of relapse-onset MS within the HLA region
-
de Jong BA, Huizinga TW, Zanelli E, Giphart MJ, Bollen EL, Uitdehaag BM, et al. Evidence for additional genetic risk indicators of relapse-onset MS within the HLA region. Neurology 2002; 59: 549-55.
-
(2002)
Neurology
, vol.59
, pp. 549-555
-
-
de Jong, B.A.1
Huizinga, T.W.2
Zanelli, E.3
Giphart, M.J.4
Bollen, E.L.5
Uitdehaag, B.M.6
-
23
-
-
16544380910
-
Genomic control to the extreme
-
author reply 1131
-
Devlin B, Bacanu SA, Roeder K. Genomic control to the extreme. Nat Genet 2004; 36: 1129-30; author reply 1131.
-
(2004)
Nat Genet
, vol.36
, pp. 1129-1130
-
-
Devlin, B.1
Bacanu, S.A.2
Roeder, K.3
-
24
-
-
0032714352
-
Genomic control for association studies
-
Devlin B, Roeder K. Genomic control for association studies. Biometrics 1999; 55: 997-1004.
-
(1999)
Biometrics
, vol.55
, pp. 997-1004
-
-
Devlin, B.1
Roeder, K.2
-
25
-
-
33845340501
-
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene
-
Duerr RH, Taylor KD, Brant SR, Rioux JD, Silverberg MS, Daly MJ, et al. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science 2006; 314: 1461-3.
-
(2006)
Science
, vol.314
, pp. 1461-1463
-
-
Duerr, R.H.1
Taylor, K.D.2
Brant, S.R.3
Rioux, J.D.4
Silverberg, M.S.5
Daly, M.J.6
-
26
-
-
0036317753
-
A multigenerational family with multiple sclerosis
-
Dyment DA, Cader MZ, Willer CJ, Risch N, Sadovnick AD, Ebers GC. A multigenerational family with multiple sclerosis. Brain 2002; 125: 1474-82.
-
(2002)
Brain
, vol.125
, pp. 1474-1482
-
-
Dyment, D.A.1
Cader, M.Z.2
Willer, C.J.3
Risch, N.4
Sadovnick, A.D.5
Ebers, G.C.6
-
27
-
-
26444469579
-
Complex interactions among MHC haplotypes in multiple sclerosis: Susceptibility and resistance
-
Dyment DA, Herrera BM, Cader MZ, Willer CJ, Lincoln MR, Sadovnick AD, et al. Complex interactions among MHC haplotypes in multiple sclerosis: susceptibility and resistance. Hum Mol Genet 2005; 14: 2019-26.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 2019-2026
-
-
Dyment, D.A.1
Herrera, B.M.2
Cader, M.Z.3
Willer, C.J.4
Lincoln, M.R.5
Sadovnick, A.D.6
-
28
-
-
2542547323
-
An extended genome scan in 442 Canadian multiple sclerosis-affected sibships: A report from the Canadian Collaborative Study Group
-
Dyment DA, Sadovnick AD, Willer CJ, Armstrong H, Cader ZM, Wiltshire S, et al. An extended genome scan in 442 Canadian multiple sclerosis-affected sibships: a report from the Canadian Collaborative Study Group. Hum Mol Genet 2004; 13: 1005-15.
-
(2004)
Hum Mol Genet
, vol.13
, pp. 1005-1015
-
-
Dyment, D.A.1
Sadovnick, A.D.2
Willer, C.J.3
Armstrong, H.4
Cader, Z.M.5
Wiltshire, S.6
-
30
-
-
34250006413
-
Genome-wide association study identifies novel breast cancer susceptibility loci
-
Easton DF, Pooley KA, Dunning AM, Pharoah PD, Thompson D, Ballinger DG, et al. Genome-wide association study identifies novel breast cancer susceptibility loci. Nature 2007; 447: 1087-93.
-
(2007)
Nature
, vol.447
, pp. 1087-1093
-
-
Easton, D.F.1
Pooley, K.A.2
Dunning, A.M.3
Pharoah, P.D.4
Thompson, D.5
Ballinger, D.G.6
-
31
-
-
15844366743
-
A full genome search in multiple sclerosis
-
Ebers GC, Kukay K, Bulman DE, Sadovnick AD, Rice G, Anderson C, et al. A full genome search in multiple sclerosis. Nat Genet 1996; 13: 472-6.
-
(1996)
Nat Genet
, vol.13
, pp. 472-476
-
-
Ebers, G.C.1
Kukay, K.2
Bulman, D.E.3
Sadovnick, A.D.4
Rice, G.5
Anderson, C.6
-
32
-
-
2542541258
-
Parent-of-origin effect in multiple sclerosis: Observations in half-siblings
-
Ebers GC, Sadovnick AD, Dyment DA, Yee IM, Willer CJ, Risch N. Parent-of-origin effect in multiple sclerosis: observations in half-siblings. Lancet 2004; 363: 1773-4.
-
(2004)
Lancet
, vol.363
, pp. 1773-1774
-
-
Ebers, G.C.1
Sadovnick, A.D.2
Dyment, D.A.3
Yee, I.M.4
Willer, C.J.5
Risch, N.6
-
33
-
-
0029121088
-
A genetic basis for familial aggregation in multiple sclerosis. Canadian Collaborative Study Group
-
Ebers GC, Sadovnick AD, Risch NJ. A genetic basis for familial aggregation in multiple sclerosis. Canadian Collaborative Study Group. Nature 1995; 377: 150-1.
-
(1995)
Nature
, vol.377
, pp. 150-151
-
-
Ebers, G.C.1
Sadovnick, A.D.2
Risch, N.J.3
-
34
-
-
0033674248
-
Conjugal multiple sclerosis: Population-based prevalence and recurrence risks in offspring. Canadian Collaborative Study Group
-
Ebers GC, Yee IM, Sadovnick AD, Duquette P. Conjugal multiple sclerosis: population-based prevalence and recurrence risks in offspring. Canadian Collaborative Study Group. Ann Neurol 2000; 48: 927-31.
-
(2000)
Ann Neurol
, vol.48
, pp. 927-931
-
-
Ebers, G.C.1
Yee, I.M.2
Sadovnick, A.D.3
Duquette, P.4
-
35
-
-
25444509248
-
Power and sample size calculations in the presence of phenotype errors for case/control genetic association studies
-
Edwards BJ, Haynes C, Levenstien MA, Finch SJ, Gordon D. Power and sample size calculations in the presence of phenotype errors for case/control genetic association studies. BMC Genet 2005; 6: 18.
-
(2005)
BMC Genet
, vol.6
, pp. 18
-
-
Edwards, B.J.1
Haynes, C.2
Levenstien, M.A.3
Finch, S.J.4
Gordon, D.5
-
36
-
-
10744229264
-
A whole genome screen for linkage in Turkish multiple sclerosis
-
Eraksoy M, Kurtuncu M, Akman-Demir G, Kilinc M, Gedizlioglu M, Mirza M, et al. A whole genome screen for linkage in Turkish multiple sclerosis. J Neuroimmunol 2003; 143: 17-24.
-
(2003)
J Neuroimmunol
, vol.143
, pp. 17-24
-
-
Eraksoy, M.1
Kurtuncu, M.2
Akman-Demir, G.3
Kilinc, M.4
Gedizlioglu, M.5
Mirza, M.6
-
37
-
-
24344436429
-
Mapping gene activity in complex disorders: Integration of expression and genomic scans for multiple sclerosis
-
Fernald GH, Yeh RF, Hauser SL, Oksenberg JR, Baranzini SE. Mapping gene activity in complex disorders: Integration of expression and genomic scans for multiple sclerosis. J Neuroimmunol 2005; 167: 157-69.
-
(2005)
J Neuroimmunol
, vol.167
, pp. 157-169
-
-
Fernald, G.H.1
Yeh, R.F.2
Hauser, S.L.3
Oksenberg, J.R.4
Baranzini, S.E.5
-
38
-
-
0033975139
-
Multiple sclerosis: A modifying influence of HLA class I genes in an HLA class II associated autoimmune disease
-
Fogdell-Hahn A, Ligers A, Gronning M, Hillert J, Olerup O. Multiple sclerosis: a modifying influence of HLA class I genes in an HLA class II associated autoimmune disease. Tissue Antigens 2000; 55: 140-8.
-
(2000)
Tissue Antigens
, vol.55
, pp. 140-148
-
-
Fogdell-Hahn, A.1
Ligers, A.2
Gronning, M.3
Hillert, J.4
Olerup, O.5
-
39
-
-
35348983887
-
A second generation human haplotype map of over 3.1 million SNPs
-
Frazer KA, Ballinger DG, Cox DR, Hinds DA, Stuve LL, Gibbs RA, et al. A second generation human haplotype map of over 3.1 million SNPs. Nature 2007; 449: 851-61.
-
(2007)
Nature
, vol.449
, pp. 851-861
-
-
Frazer, K.A.1
Ballinger, D.G.2
Cox, D.R.3
Hinds, D.A.4
Stuve, L.L.5
Gibbs, R.A.6
-
40
-
-
6944252244
-
The use of pedigree, sib-pair and association studies of common diseases for genetic mapping and epidemiology
-
Freimer N, Sabatti C. The use of pedigree, sib-pair and association studies of common diseases for genetic mapping and epidemiology. Nat Genet 2004; 36: 1045-51.
-
(2004)
Nat Genet
, vol.36
, pp. 1045-1051
-
-
Freimer, N.1
Sabatti, C.2
-
41
-
-
0026497413
-
Multiple sclerosis in 54 twinships: Concordance rate is independent of zygosity
-
French Research Group on Multiple Sclerosis
-
French Research Group on Multiple Sclerosis. Multiple sclerosis in 54 twinships: concordance rate is independent of zygosity. Ann Neurol 1992; 32: 724-7.
-
(1992)
Ann Neurol
, vol.32
, pp. 724-727
-
-
-
42
-
-
0142186253
-
A meta-analysis of whole genome linkage screens in multiple sclerosis
-
Genetic Analysis of Multiple Sclerosis in EuropeanS (GAMES) and the Transatlantic Multiple Sclerosis Genetics Cooperative
-
Genetic Analysis of Multiple Sclerosis in EuropeanS (GAMES) and the Transatlantic Multiple Sclerosis Genetics Cooperative. A meta-analysis of whole genome linkage screens in multiple sclerosis. J Neuroimmunol 2003; 143: 39-46.
-
(2003)
J Neuroimmunol
, vol.143
, pp. 39-46
-
-
-
43
-
-
1842859051
-
Power and sample size calculations for case-control genetic association tests when errors are present: Application to single nucleotide polymorphisms
-
Gordon D, Finch SJ, Nothnagel M, Ott J. Power and sample size calculations for case-control genetic association tests when errors are present: application to single nucleotide polymorphisms. Hum Hered 2002; 54: 22-33.
-
(2002)
Hum Hered
, vol.54
, pp. 22-33
-
-
Gordon, D.1
Finch, S.J.2
Nothnagel, M.3
Ott, J.4
-
44
-
-
0035209177
-
Large upward bias in estimation of locus-specific effects from genomewide scans
-
Goring HH, Terwilliger JD, Blangero J. Large upward bias in estimation of locus-specific effects from genomewide scans. Am J Hum Genet 2001; 69: 1357-69.
-
(2001)
Am J Hum Genet
, vol.69
, pp. 1357-1369
-
-
Goring, H.H.1
Terwilliger, J.D.2
Blangero, J.3
-
45
-
-
34548351247
-
Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis
-
Gregory SG, Schmidt S, Seth P, Oksenberg JR, Hart J, Prokop A, et al. Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis. Nat Genet 2007; 39: 1083-91.
-
(2007)
Nat Genet
, vol.39
, pp. 1083-1091
-
-
Gregory, S.G.1
Schmidt, S.2
Seth, P.3
Oksenberg, J.R.4
Hart, J.5
Prokop, A.6
-
46
-
-
34247563453
-
Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24
-
Gudmundsson J, Sulem P, Manolescu A, Amundadottir LT, Gudbjartsson D, Helgason A, et al. Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24. Nat Genet 2007; 39: 631-7.
-
(2007)
Nat Genet
, vol.39
, pp. 631-637
-
-
Gudmundsson, J.1
Sulem, P.2
Manolescu, A.3
Amundadottir, L.T.4
Gudbjartsson, D.5
Helgason, A.6
-
47
-
-
0036183653
-
Sibling recurrence risk ratio as a measure of genetic effect: Caveat emptor!
-
Guo SW. Sibling recurrence risk ratio as a measure of genetic effect: caveat emptor! Am J Hum Genet 2002; 70: 818-9.
-
(2002)
Am J Hum Genet
, vol.70
, pp. 818-819
-
-
Guo, S.W.1
-
48
-
-
0009573338
-
A complete genomic screen for multiple sclerosis underscores a role for the major histocompatability complex. The Multiple Sclerosis Genetics Group
-
Haines JL, Ter-Minassian M, Bazyk A, Gusella JF, Kim DJ, Terwedow H, et al. A complete genomic screen for multiple sclerosis underscores a role for the major histocompatability complex. The Multiple Sclerosis Genetics Group. Nat Genet 1996; 13: 469-71.
-
(1996)
Nat Genet
, vol.13
, pp. 469-471
-
-
Haines, J.L.1
Ter-Minassian, M.2
Bazyk, A.3
Gusella, J.F.4
Kim, D.J.5
Terwedow, H.6
-
49
-
-
33846627302
-
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
-
Hampe J, Franke A, Rosenstiel P, Till A, Teuber M, Huse K, et al. A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nat Genet 2007; 39: 207-11.
-
(2007)
Nat Genet
, vol.39
, pp. 207-211
-
-
Hampe, J.1
Franke, A.2
Rosenstiel, P.3
Till, A.4
Teuber, M.5
Huse, K.6
-
50
-
-
25844442849
-
Concordance for multiple sclerosis in Danish twins: An update of a nationwide study
-
Hansen T, Skytthe A, Stenager E, Petersen HC, Bronnum-Hansen H, Kyvik KO. Concordance for multiple sclerosis in Danish twins: an update of a nationwide study. Mult Scler 2005; 11: 504-10.
-
(2005)
Mult Scler
, vol.11
, pp. 504-510
-
-
Hansen, T.1
Skytthe, A.2
Stenager, E.3
Petersen, H.C.4
Bronnum-Hansen, H.5
Kyvik, K.O.6
-
51
-
-
10744231677
-
Genes in the HLA class I region may contribute to the HLA class II-associated genetic susceptibility to multiple sclerosis
-
Harbo HF, Lie BA, Sawcer S, Celius EG, Dai KZ, Oturai A, et al. Genes in the HLA class I region may contribute to the HLA class II-associated genetic susceptibility to multiple sclerosis. Tissue Antigens 2004; 63: 237-47.
-
(2004)
Tissue Antigens
, vol.63
, pp. 237-247
-
-
Harbo, H.F.1
Lie, B.A.2
Sawcer, S.3
Celius, E.G.4
Dai, K.Z.5
Oturai, A.6
-
52
-
-
0026782507
-
Occurrence of a multiple sclerosis-like illness in women who have a Leber's hereditary optic neuropathy mitochondrial DNA mutation
-
Harding AE, Sweeney MG, Miller DH, Mumford CJ, Kellar-Wood H, Menard D, et al. Occurrence of a multiple sclerosis-like illness in women who have a Leber's hereditary optic neuropathy mitochondrial DNA mutation. Brain 1992; 115 (Pt 4): 979-89.
-
(1992)
Brain
, vol.115
, Issue.PART 4
, pp. 979-989
-
-
Harding, A.E.1
Sweeney, M.G.2
Miller, D.H.3
Mumford, C.J.4
Kellar-Wood, H.5
Menard, D.6
-
53
-
-
0037444214
-
Genomic convergence: Identifying candidate genes for Parkinson's disease by combining serial analysis of gene expression and genetic linkage
-
Hauser MA, Li YJ, Takeuchi S, Walters R, Noureddine M, Maready M, et al. Genomic convergence: identifying candidate genes for Parkinson's disease by combining serial analysis of gene expression and genetic linkage. Hum Mol Genet 2003; 12: 671-7.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 671-677
-
-
Hauser, M.A.1
Li, Y.J.2
Takeuchi, S.3
Walters, R.4
Noureddine, M.5
Maready, M.6
-
54
-
-
34250010480
-
A common variant on chromosome 9p21 affects the risk of myocardial infarction
-
Helgadottir A, Thorleifsson G, Manolescu A, Gretarsdottir S, Blondal T, Jonasdottir A, et al. A common variant on chromosome 9p21 affects the risk of myocardial infarction. Science 2007; 316: 1491-3.
-
(2007)
Science
, vol.316
, pp. 1491-1493
-
-
Helgadottir, A.1
Thorleifsson, G.2
Manolescu, A.3
Gretarsdottir, S.4
Blondal, T.5
Jonasdottir, A.6
-
55
-
-
0142155199
-
Updated results of the United Kingdom linkage-based genome screen in multiple sclerosis
-
Hensiek AE, Roxburgh R, Smilie B, Coraddu F, Akesson E, Holmans P, et al. Updated results of the United Kingdom linkage-based genome screen in multiple sclerosis. J Neuroimmunol 2003a; 143: 25-30.
-
(2003)
J Neuroimmunol
, vol.143
, pp. 25-30
-
-
Hensiek, A.E.1
Roxburgh, R.2
Smilie, B.3
Coraddu, F.4
Akesson, E.5
Holmans, P.6
-
56
-
-
0041589265
-
Searching for needles in haystacks-the genetics of multiple sclerosis and other common neurological diseases
-
Hensiek AE, Sawcer SJ, Compston DA. Searching for needles in haystacks-the genetics of multiple sclerosis and other common neurological diseases. Brain Res Bull 2003b; 61: 229-34.
-
(2003)
Brain Res Bull
, vol.61
, pp. 229-234
-
-
Hensiek, A.E.1
Sawcer, S.J.2
Compston, D.A.3
-
57
-
-
33846566857
-
Familial effects on the clinical course of multiple sclerosis
-
Hensiek AE, Seaman SR, Barcellos LF, Oturai A, Eraksoi M, Cocco E, et al. Familial effects on the clinical course of multiple sclerosis. Neurology 2007; 68: 376-83.
-
(2007)
Neurology
, vol.68
, pp. 376-383
-
-
Hensiek, A.E.1
Seaman, S.R.2
Barcellos, L.F.3
Oturai, A.4
Eraksoi, M.5
Cocco, E.6
-
58
-
-
34548803934
-
Parental transmission of MS in a population-based Canadian cohort
-
Herrera BM, Ramagopalan SV, Orton S, Chao MJ, Yee IM, Sadovnick AD, et al. Parental transmission of MS in a population-based Canadian cohort. Neurology 2007; 69: 1208-12.
-
(2007)
Neurology
, vol.69
, pp. 1208-1212
-
-
Herrera, B.M.1
Ramagopalan, S.V.2
Orton, S.3
Chao, M.J.4
Yee, I.M.5
Sadovnick, A.D.6
-
60
-
-
9444295337
-
-
Horton R, Wilming L, Rand V, Lovering RC, Bruford EA, Khodiyar VK, et al. Gene map of the extended human MHC. Nat Rev Genet 2004; 5: 889-99.
-
Horton R, Wilming L, Rand V, Lovering RC, Bruford EA, Khodiyar VK, et al. Gene map of the extended human MHC. Nat Rev Genet 2004; 5: 889-99.
-
-
-
-
61
-
-
38349100266
-
Variation analysis and gene annotation of eight MHC haplotypes: The MHC Haplotype Project
-
Horton R, Gibson R, Coggill P, Miretti M, Allcock RJ, Almeida J, et al. Variation analysis and gene annotation of eight MHC haplotypes: The MHC Haplotype Project. Immunogenetics 2008; 60: 1-18.
-
(2008)
Immunogenetics
, vol.60
, pp. 1-18
-
-
Horton, R.1
Gibson, R.2
Coggill, P.3
Miretti, M.4
Allcock, R.J.5
Almeida, J.6
-
62
-
-
7244245762
-
Finishing the euchromatic sequence of the human genome
-
Human genome project
-
Human genome project. Finishing the euchromatic sequence of the human genome. Nature 2004; 431: 931-45.
-
(2004)
Nature
, vol.431
, pp. 931-945
-
-
-
63
-
-
34250001297
-
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer
-
Hunter DJ, Kraft P, Jacobs KB, Cox DG, Yeager M, Hankinson SE, et al. A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer. Nat Genet 2007; 39: 870-4.
-
(2007)
Nat Genet
, vol.39
, pp. 870-874
-
-
Hunter, D.J.1
Kraft, P.2
Jacobs, K.B.3
Cox, D.G.4
Yeager, M.5
Hankinson, S.E.6
-
64
-
-
0035943035
-
Patterns of disease in concordant parent-child pairs with multiple sclerosis
-
Hupperts R, Broadley S, Mander A, Clayton D, Compston DA, Robertson NP. Patterns of disease in concordant parent-child pairs with multiple sclerosis. Neurology 2001; 57: 290-5.
-
(2001)
Neurology
, vol.57
, pp. 290-295
-
-
Hupperts, R.1
Broadley, S.2
Mander, A.3
Clayton, D.4
Compston, D.A.5
Robertson, N.P.6
-
65
-
-
79959503826
-
-
International HapMap Project
-
International HapMap Project. Nature 2003; 426: 789-96.
-
(2003)
Nature
, vol.426
, pp. 789-796
-
-
-
66
-
-
4544358404
-
Enhancing linkage analysis of complex disorders: An evaluation of high-density genotyping
-
International Multiple Sclerosis Genetics Consortium IMSGC
-
International Multiple Sclerosis Genetics Consortium (IMSGC). Enhancing linkage analysis of complex disorders: an evaluation of high-density genotyping. Hum Mol Genet 2004; 13: 1943-9.
-
(2004)
Hum Mol Genet
, vol.13
, pp. 1943-1949
-
-
-
67
-
-
23944499790
-
A high-density screen for linkage in multiple sclerosis
-
International Multiple Sclerosis Genetics Consortium IMSGC
-
International Multiple Sclerosis Genetics Consortium (IMSGC). A high-density screen for linkage in multiple sclerosis. Am J Hum Genet 2005; 77: 454-67.
-
(2005)
Am J Hum Genet
, vol.77
, pp. 454-467
-
-
-
68
-
-
34548299105
-
Risk Alleles for Multiple Sclerosis Identified by a Genomewide Study
-
International Multiple Sclerosis Genetics Consortium IMSGC
-
International Multiple Sclerosis Genetics Consortium (IMSGC). Risk Alleles for Multiple Sclerosis Identified by a Genomewide Study. N Engl J Med 2007; 357: 851-62.
-
(2007)
N Engl J Med
, vol.357
, pp. 851-862
-
-
-
69
-
-
0038813649
-
Genetic associations: False or true?
-
Ioannidis JP. Genetic associations: false or true? Trends Mol Med 2003; 9: 135-8.
-
(2003)
Trends Mol Med
, vol.9
, pp. 135-138
-
-
Ioannidis, J.P.1
-
70
-
-
33749013001
-
Implications of small effect sizes of individual genetic variants on the design and interpretation of genetic association studies of complex diseases
-
Ioannidis JP, Trikalinos TA, Khoury MJ. Implications of small effect sizes of individual genetic variants on the design and interpretation of genetic association studies of complex diseases. Am J Epidemiol 2006; 164: 609-14.
-
(2006)
Am J Epidemiol
, vol.164
, pp. 609-614
-
-
Ioannidis, J.P.1
Trikalinos, T.A.2
Khoury, M.J.3
-
71
-
-
33745728408
-
Differential twin concordance for multiple sclerosis by latitude of birthplace
-
Islam T, Gauderman WJ, Cozen W, Hamilton AS, Burnett ME, Mack TM. Differential twin concordance for multiple sclerosis by latitude of birthplace. Ann Neurol 2006; 60: 56-64.
-
(2006)
Ann Neurol
, vol.60
, pp. 56-64
-
-
Islam, T.1
Gauderman, W.J.2
Cozen, W.3
Hamilton, A.S.4
Burnett, M.E.5
Mack, T.M.6
-
72
-
-
0015733713
-
Histocompatibility determinants in multiple sclerosis, with special reference to clinical course
-
Jersild C, Fog T, Hansen GS, Thomsen M, Svejgaard A, Dupont B. Histocompatibility determinants in multiple sclerosis, with special reference to clinical course. Lancet 1973; 2: 1221-5.
-
(1973)
Lancet
, vol.2
, pp. 1221-1225
-
-
Jersild, C.1
Fog, T.2
Hansen, G.S.3
Thomsen, M.4
Svejgaard, A.5
Dupont, B.6
-
73
-
-
0015492877
-
HL-A antigens and multiple sclerosis
-
Jersild C, Svejgaard A, Fog T. HL-A antigens and multiple sclerosis. Lancet 1972; 1: 1240-1.
-
(1972)
Lancet
, vol.1
, pp. 1240-1241
-
-
Jersild, C.1
Svejgaard, A.2
Fog, T.3
-
74
-
-
33747048991
-
Men transmit MS more often to their children vs women: The Carter effect
-
Kantarci OH, Barcellos LF, Atkinson EJ, Ramsay PP, Lincoln R, Achenbach SJ, et al. Men transmit MS more often to their children vs women: the Carter effect. Neurology 2006; 67: 305-10.
-
(2006)
Neurology
, vol.67
, pp. 305-310
-
-
Kantarci, O.H.1
Barcellos, L.F.2
Atkinson, E.J.3
Ramsay, P.P.4
Lincoln, R.5
Achenbach, S.J.6
-
75
-
-
8844236880
-
A second-generation genomic screen for multiple sclerosis
-
Kenealy SJ, Babron MC, Bradford Y, Schnetz-Boutaud N, Haines JL, Rimmler JB, et al. A second-generation genomic screen for multiple sclerosis. Am J Hum Genet 2004; 75: 1070-8.
-
(2004)
Am J Hum Genet
, vol.75
, pp. 1070-1078
-
-
Kenealy, S.J.1
Babron, M.C.2
Bradford, Y.3
Schnetz-Boutaud, N.4
Haines, J.L.5
Rimmler, J.B.6
-
76
-
-
0033815851
-
Conditional ETDT analysis of the human leukocyte antigen region in type 1 diabetes
-
Koeleman BP, Herr MH, Zavattari P, Dudbridge F, March R, Campbell D, et al. Conditional ETDT analysis of the human leukocyte antigen region in type 1 diabetes. Ann Hum Genet 2000; 64: 215-21.
-
(2000)
Ann Hum Genet
, vol.64
, pp. 215-221
-
-
Koeleman, B.P.1
Herr, M.H.2
Zavattari, P.3
Dudbridge, F.4
March, R.5
Campbell, D.6
-
77
-
-
33244486947
-
The natural history of multiple sclerosis: A geographically based study 9: observations on the progressive phase of the disease
-
Kremenchutzky M, Rice GP, Baskerville J, Wingerchuk DM, Ebers GC. The natural history of multiple sclerosis: a geographically based study 9: observations on the progressive phase of the disease. Brain 2006; 129: 584-94.
-
(2006)
Brain
, vol.129
, pp. 584-594
-
-
Kremenchutzky, M.1
Rice, G.P.2
Baskerville, J.3
Wingerchuk, D.M.4
Ebers, G.C.5
-
78
-
-
0035094764
-
Variation is the spice of life
-
Kruglyak L, Nickerson DA. Variation is the spice of life. Nat Genet 2001; 27: 234-6.
-
(2001)
Nat Genet
, vol.27
, pp. 234-236
-
-
Kruglyak, L.1
Nickerson, D.A.2
-
79
-
-
17344367913
-
Genomewide scan of multiple sclerosis in Finnish multiplex families
-
Kuokkanen S, Gschwend M, Rioux JD, Daly MJ, Terwilliger JD, Tienari PJ, et al. Genomewide scan of multiple sclerosis in Finnish multiplex families. Am J Hum Genet 1997; 61: 1379-87.
-
(1997)
Am J Hum Genet
, vol.61
, pp. 1379-1387
-
-
Kuokkanen, S.1
Gschwend, M.2
Rioux, J.D.3
Daly, M.J.4
Terwilliger, J.D.5
Tienari, P.J.6
-
80
-
-
0028090414
-
Genetic dissection of complex traits
-
Lander ES, Schork NJ. Genetic dissection of complex traits. Science 1994; 265: 2037-48.
-
(1994)
Science
, vol.265
, pp. 2037-2048
-
-
Lander, E.S.1
Schork, N.J.2
-
81
-
-
23944444890
-
IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel
-
Lennon VA, Kryzer TJ, Pittock SJ, Verkman AS, Hinson SR. IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel. J Exp Med 2005; 202: 473-7.
-
(2005)
J Exp Med
, vol.202
, pp. 473-477
-
-
Lennon, V.A.1
Kryzer, T.J.2
Pittock, S.J.3
Verkman, A.S.4
Hinson, S.R.5
-
82
-
-
10344250945
-
A serum autoantibody marker of neuromyelitis optica: Distinction from multiple sclerosis
-
Lennon VA, Wingerchuk DM, Kryzer TJ, Pittock SJ, Lucchinetti CF, Fujihara K, et al. A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis. Lancet 2004; 364: 2106-12.
-
(2004)
Lancet
, vol.364
, pp. 2106-2112
-
-
Lennon, V.A.1
Wingerchuk, D.M.2
Kryzer, T.J.3
Pittock, S.J.4
Lucchinetti, C.F.5
Fujihara, K.6
-
83
-
-
34247579326
-
Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4
-
Libioulle C, Louis E, Hansoul S, Sandor C, Farnir F, Franchimont D, et al. Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4. PLoS Genet 2007; 3: e58.
-
(2007)
PLoS Genet
, vol.3
-
-
Libioulle, C.1
Louis, E.2
Hansoul, S.3
Sandor, C.4
Farnir, F.5
Franchimont, D.6
-
84
-
-
0034835051
-
Evidence of linkage with HLA-DR in DRB1*15-negative families with multiple sclerosis
-
Ligers A, Dyment DA, Willer CJ, Sadovnick AD, Ebers G, Risch N, et al. Evidence of linkage with HLA-DR in DRB1*15-negative families with multiple sclerosis. Am J Hum Genet 2001; 69: 900-3.
-
(2001)
Am J Hum Genet
, vol.69
, pp. 900-903
-
-
Ligers, A.1
Dyment, D.A.2
Willer, C.J.3
Sadovnick, A.D.4
Ebers, G.5
Risch, N.6
-
85
-
-
27144538977
-
A predominant role for the HLA class II region in the association of the MHC region with multiple sclerosis
-
Lincoln MR, Montpetit A, Cader MZ, Saarela J, Dyment DA, Tiislar M, et al. A predominant role for the HLA class II region in the association of the MHC region with multiple sclerosis. Nat Genet 2005; 37: 1108-12.
-
(2005)
Nat Genet
, vol.37
, pp. 1108-1112
-
-
Lincoln, M.R.1
Montpetit, A.2
Cader, M.Z.3
Saarela, J.4
Dyment, D.A.5
Tiislar, M.6
-
86
-
-
18244383791
-
Familial recurrence rates and genetic models of multiple sclerosis
-
Lindsey JW. Familial recurrence rates and genetic models of multiple sclerosis. Am J Med Genet A 2005; 135: 53-8.
-
(2005)
Am J Med Genet A
, vol.135
, pp. 53-58
-
-
Lindsey, J.W.1
-
87
-
-
0037312921
-
Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease
-
Lohmueller KE, Pearce CL, Pike M, Lander ES, Hirschhorn JN. Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease. Nat Genet 2003; 33: 177-82.
-
(2003)
Nat Genet
, vol.33
, pp. 177-182
-
-
Lohmueller, K.E.1
Pearce, C.L.2
Pike, M.3
Lander, E.S.4
Hirschhorn, J.N.5
-
88
-
-
34548368541
-
Variation in interleukin 7 receptor alpha chain (IL7R) influences risk of multiple sclerosis
-
Lundmark F, Duvefelt K, Iacobaeus E, Kockum I, Wallstrom E, Khademi M, et al. Variation in interleukin 7 receptor alpha chain (IL7R) influences risk of multiple sclerosis. Nat Genet 2007; 39: 1108-13.
-
(2007)
Nat Genet
, vol.39
, pp. 1108-1113
-
-
Lundmark, F.1
Duvefelt, K.2
Iacobaeus, E.3
Kockum, I.4
Wallstrom, E.5
Khademi, M.6
-
89
-
-
0031824226
-
DRB1-DQA1-DQB1 loci and multiple sclerosis predisposition in the Sardinian population
-
Marrosu MG, Murru MR, Costa G, Murru R, Muntoni F, Cucca F. DRB1-DQA1-DQB1 loci and multiple sclerosis predisposition in the Sardinian population. Hum Mol Genet 1998; 7: 1235-7.
-
(1998)
Hum Mol Genet
, vol.7
, pp. 1235-1237
-
-
Marrosu, M.G.1
Murru, M.R.2
Costa, G.3
Murru, R.4
Muntoni, F.5
Cucca, F.6
-
90
-
-
18244367163
-
Dissection of the HLA association with multiple sclerosis in the founder isolated population of Sardinia
-
Marrosu MG, Murru R, Murru MR, Costa G, Zavattari P, Whalen M, et al. Dissection of the HLA association with multiple sclerosis in the founder isolated population of Sardinia. Hum Mol Genet 2001; 10: 2907-16.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 2907-2916
-
-
Marrosu, M.G.1
Murru, R.2
Murru, M.R.3
Costa, G.4
Zavattari, P.5
Whalen, M.6
-
91
-
-
0034955141
-
Recommended diagnostic criteria for multiple sclerosis: Guidelines from the International Panel on the diagnosis of multiple sclerosis
-
McDonald WI, Compston A, Edan G, Goodkin D, Hartung HP, Lublin FD, et al. Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis. Ann Neurol 2001; 50: 121-7.
-
(2001)
Ann Neurol
, vol.50
, pp. 121-127
-
-
McDonald, W.I.1
Compston, A.2
Edan, G.3
Goodkin, D.4
Hartung, H.P.5
Lublin, F.D.6
-
92
-
-
34249996115
-
A common allele on chromosome 9 associated with coronary heart disease
-
McPherson R, Pertsemlidis A, Kavaslar N, Stewart A, Roberts R, Cox DR, et al. A common allele on chromosome 9 associated with coronary heart disease. Science 2007; 316: 1488-91.
-
(2007)
Science
, vol.316
, pp. 1488-1491
-
-
McPherson, R.1
Pertsemlidis, A.2
Kavaslar, N.3
Stewart, A.4
Roberts, R.5
Cox, D.R.6
-
93
-
-
20144388362
-
A high-resolution linkage-disequilibrium map of the human major histocompatibility complex and first generation of tag single-nucleotide polymorphisms
-
Miretti MM, Walsh EC, Ke X, Delgado M, Griffiths M, Hunt S, et al. A high-resolution linkage-disequilibrium map of the human major histocompatibility complex and first generation of tag single-nucleotide polymorphisms. Am J Hum Genet 2005; 76: 634-46.
-
(2005)
Am J Hum Genet
, vol.76
, pp. 634-646
-
-
Miretti, M.M.1
Walsh, E.C.2
Ke, X.3
Delgado, M.4
Griffiths, M.5
Hunt, S.6
-
94
-
-
0037356710
-
Genome-wide linkage screen of a consanguineous multiple sclerosis kinship
-
Modin H, Masterman T, Thorlacius T, Stefansson M, Jonasdottir A, Stefansson K, et al. Genome-wide linkage screen of a consanguineous multiple sclerosis kinship. Mult Scler 2003; 9: 128-34.
-
(2003)
Mult Scler
, vol.9
, pp. 128-134
-
-
Modin, H.1
Masterman, T.2
Thorlacius, T.3
Stefansson, M.4
Jonasdottir, A.5
Stefansson, K.6
-
95
-
-
34247576159
-
Detailed analysis of the relative power of direct and indirect association studies and the implications for their interpretation
-
Moskvina V, O'Donovan MC. Detailed analysis of the relative power of direct and indirect association studies and the implications for their interpretation. Hum Hered 2007; 64: 63-73.
-
(2007)
Hum Hered
, vol.64
, pp. 63-73
-
-
Moskvina, V.1
O'Donovan, M.C.2
-
96
-
-
0028128084
-
The British Isles survey of multiple sclerosis in twins
-
Mumford CJ, Wood NW, Kellar-Wood H, Thorpe JW, Miller DH, Compston DA. The British Isles survey of multiple sclerosis in twins. Neurology 1994; 44: 11-5.
-
(1994)
Neurology
, vol.44
, pp. 11-15
-
-
Mumford, C.J.1
Wood, N.W.2
Kellar-Wood, H.3
Thorpe, J.W.4
Miller, D.H.5
Compston, D.A.6
-
98
-
-
9144269888
-
Mapping multiple sclerosis susceptibility to the HLA-DR locus in African Americans
-
Oksenberg JR, Barcellos LF, Cree BA, Baranzini SE, Bugawan TL, Khan O, et al. Mapping multiple sclerosis susceptibility to the HLA-DR locus in African Americans. Am J Hum Genet 2004; 74: 160-7.
-
(2004)
Am J Hum Genet
, vol.74
, pp. 160-167
-
-
Oksenberg, J.R.1
Barcellos, L.F.2
Cree, B.A.3
Baranzini, S.E.4
Bugawan, T.L.5
Khan, O.6
-
99
-
-
0025767289
-
HLA class II-associated genetic susceptibility in multiple sclerosis: A critical evaluation
-
Olerup O, Hillert J. HLA class II-associated genetic susceptibility in multiple sclerosis: a critical evaluation. Tissue Antigens 1991; 38: 1-15.
-
(1991)
Tissue Antigens
, vol.38
, pp. 1-15
-
-
Olerup, O.1
Hillert, J.2
-
100
-
-
33745279392
-
Evaluating and improving power in whole-genome association studies using fixed marker sets
-
Pe'er I, de Bakker PI, Maller J, Yelensky R, Altshuler D, Daly MJ. Evaluating and improving power in whole-genome association studies using fixed marker sets. Nat Genet 2006; 38: 663-7.
-
(2006)
Nat Genet
, vol.38
, pp. 663-667
-
-
Pe'er, I.1
de Bakker, P.I.2
Maller, J.3
Yelensky, R.4
Altshuler, D.5
Daly, M.J.6
-
101
-
-
0030744876
-
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease
-
Polymeropoulos MH, Lavedan C, Leroy E, Ide SE, Dehejia A, Dutra A, et al. Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science 1997; 276: 2045-7.
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
Dutra, A.6
-
102
-
-
0036799545
-
The allelic architecture of human disease genes: Common disease-common variant . . . or not?
-
Pritchard JK, Cox NJ. The allelic architecture of human disease genes: common disease-common variant . . . or not? Hum Mol Genet 2002; 11: 2417-23.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 2417-2423
-
-
Pritchard, J.K.1
Cox, N.J.2
-
103
-
-
12244264435
-
Genetic Power Calculator: Design of linkage and association genetic mapping studies of complex traits
-
Purcell S, Cherny SS, Sham PC. Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits. Bioinformatics 2003; 19: 149-50.
-
(2003)
Bioinformatics
, vol.19
, pp. 149-150
-
-
Purcell, S.1
Cherny, S.S.2
Sham, P.C.3
-
104
-
-
34848917282
-
The inheritance of resistance alleles in multiple sclerosis
-
Ramagopalan SV, Morris AP, Dyment DA, Herrera BM, DeLuca GC, Lincoln MR, et al. The inheritance of resistance alleles in multiple sclerosis. PLoS Genet 2007; 3: 1607-13.
-
(2007)
PLoS Genet
, vol.3
, pp. 1607-1613
-
-
Ramagopalan, S.V.1
Morris, A.P.2
Dyment, D.A.3
Herrera, B.M.4
DeLuca, G.C.5
Lincoln, M.R.6
-
105
-
-
27144472560
-
A whole-genome admixture scan finds a candidate locus for multiple sclerosis susceptibility
-
Reich D, Patterson N, Jager PL, McDonald GJ, Waliszewska A, Tandon A, et al. A whole-genome admixture scan finds a candidate locus for multiple sclerosis susceptibility. Nat Genet 2005; 37: 1113-8.
-
(2005)
Nat Genet
, vol.37
, pp. 1113-1118
-
-
Reich, D.1
Patterson, N.2
Jager, P.L.3
McDonald, G.J.4
Waliszewska, A.5
Tandon, A.6
-
106
-
-
0035451780
-
On the allelic spectrum of human disease
-
Reich DE, Lander ES. On the allelic spectrum of human disease. Trends Genet 2001; 17: 502-10.
-
(2001)
Trends Genet
, vol.17
, pp. 502-510
-
-
Reich, D.E.1
Lander, E.S.2
-
107
-
-
0028949749
-
The clinical features of Leber's hereditary optic neuropathy defined by the presence of a pathogenic mitochondrial DNA mutation
-
Riordan-Eva P, Sanders MD, Govan GG, Sweeney MG, Da Costa J, Harding AE. The clinical features of Leber's hereditary optic neuropathy defined by the presence of a pathogenic mitochondrial DNA mutation. Brain 1995; 118 (Pt 2): 319-37.
-
(1995)
Brain
, vol.118
, Issue.PART 2
, pp. 319-337
-
-
Riordan-Eva, P.1
Sanders, M.D.2
Govan, G.G.3
Sweeney, M.G.4
Da Costa, J.5
Harding, A.E.6
-
108
-
-
34247554965
-
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
-
Rioux JD, Xavier RJ, Taylor KD, Silverberg MS, Goyette P, Huett A, et al. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet 2007; 39: 596-604.
-
(2007)
Nat Genet
, vol.39
, pp. 596-604
-
-
Rioux, J.D.1
Xavier, R.J.2
Taylor, K.D.3
Silverberg, M.S.4
Goyette, P.5
Huett, A.6
-
109
-
-
0025019555
-
Linkage strategies for genetically complex traits. I. Multilocus models
-
Risch N. Linkage strategies for genetically complex traits. I. Multilocus models. Am J Hum Genet 1990; 46: 222-8.
-
(1990)
Am J Hum Genet
, vol.46
, pp. 222-228
-
-
Risch, N.1
-
110
-
-
0029741063
-
The future of genetic studies of complex human diseases
-
Risch N, Merikangas K. The future of genetic studies of complex human diseases. Science 1996; 273: 1516-7.
-
(1996)
Science
, vol.273
, pp. 1516-1517
-
-
Risch, N.1
Merikangas, K.2
-
111
-
-
29944438955
-
Multiple sclerosis in twins from continental Italy and Sardinia: A nationwide study
-
Ristori G, Cannoni S, Stazi MA, Vanacore N, Cotichini R, Alfo M, et al. Multiple sclerosis in twins from continental Italy and Sardinia: a nationwide study. Ann Neurol 2006; 59: 27-34.
-
(2006)
Ann Neurol
, vol.59
, pp. 27-34
-
-
Ristori, G.1
Cannoni, S.2
Stazi, M.A.3
Vanacore, N.4
Cotichini, R.5
Alfo, M.6
-
112
-
-
0029874022
-
Age-adjusted recurrence risks for relatives of patients with multiple sclerosis
-
Robertson NP, Fraser M, Deans J, Clayton D, Walker N, Compston DA. Age-adjusted recurrence risks for relatives of patients with multiple sclerosis. Brain 1996; 119 (Pt 2): 449-55.
-
(1996)
Brain
, vol.119
, Issue.PART 2
, pp. 449-455
-
-
Robertson, N.P.1
Fraser, M.2
Deans, J.3
Clayton, D.4
Walker, N.5
Compston, D.A.6
-
113
-
-
0030992685
-
Offspring recurrence rates and clinical characteristics of conjugal multiple sclerosis
-
Robertson NP, O'Riordan JI, Chataway J, Kingsley DP, Miller DH, Clayton D, et al. Offspring recurrence rates and clinical characteristics of conjugal multiple sclerosis. Lancet 1997; 349: 1587-90.
-
(1997)
Lancet
, vol.349
, pp. 1587-1590
-
-
Robertson, N.P.1
O'Riordan, J.I.2
Chataway, J.3
Kingsley, D.P.4
Miller, D.H.5
Clayton, D.6
-
114
-
-
18344385134
-
Genetic dissection of the human leukocyte antigen region by use of haplotypes of Tasmanians with multiple sclerosis
-
Rubio JP, Bahlo M, Butzkueven H, van Der Mei IA, Sale MM, Dickinson JL, et al. Genetic dissection of the human leukocyte antigen region by use of haplotypes of Tasmanians with multiple sclerosis. Am J Hum Genet 2002; 70: 1125-37.
-
(2002)
Am J Hum Genet
, vol.70
, pp. 1125-1137
-
-
Rubio, J.P.1
Bahlo, M.2
Butzkueven, H.3
van Der Mei, I.A.4
Sale, M.M.5
Dickinson, J.L.6
-
116
-
-
33744457667
-
A new era in the genetic analysis of multiple sclerosis
-
Sawcer S. A new era in the genetic analysis of multiple sclerosis. Curr Opin Neurol 2006; 19: 237-41.
-
(2006)
Curr Opin Neurol
, vol.19
, pp. 237-241
-
-
Sawcer, S.1
-
117
-
-
15844368830
-
A genome screen in multiple sclerosis reveals susceptibility loci on chromosome 6p21 and 17q22
-
Sawcer S, Jones HB, Feakes R, Gray J, Smaldon N, Chataway J, et al. A genome screen in multiple sclerosis reveals susceptibility loci on chromosome 6p21 and 17q22. Nat Genet 1996; 13: 464-8.
-
(1996)
Nat Genet
, vol.13
, pp. 464-468
-
-
Sawcer, S.1
Jones, H.B.2
Feakes, R.3
Gray, J.4
Smaldon, N.5
Chataway, J.6
-
118
-
-
34249888775
-
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
-
Saxena R, Voight BF, Lyssenko V, Burtt NP, de Bakker PI, Chen H, et al. Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 2007; 316: 1331-6.
-
(2007)
Science
, vol.316
, pp. 1331-1336
-
-
Saxena, R.1
Voight, B.F.2
Lyssenko, V.3
Burtt, N.P.4
de Bakker, P.I.5
Chen, H.6
-
119
-
-
34249885875
-
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants
-
Scott LJ, Mohlke KL, Bonnycastle LL, Willer CJ, Li Y, Duren WL, et al. A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. Science 2007; 316: 1341-5.
-
(2007)
Science
, vol.316
, pp. 1341-1345
-
-
Scott, L.J.1
Mohlke, K.L.2
Bonnycastle, L.L.3
Willer, C.J.4
Li, Y.5
Duren, W.L.6
-
120
-
-
33847176604
-
A genome-wide association study identifies novel risk loci for type 2 diabetes
-
Sladek R, Rocheleau G, Rung J, Dina C, Shen L, Serre D, et al. A genome-wide association study identifies novel risk loci for type 2 diabetes. Nature 2007; 445: 881-5.
-
(2007)
Nature
, vol.445
, pp. 881-885
-
-
Sladek, R.1
Rocheleau, G.2
Rung, J.3
Dina, C.4
Shen, L.5
Serre, D.6
-
121
-
-
0036798007
-
The allelic structure of common disease
-
Smith DJ, Lusis AJ. The allelic structure of common disease. Hum Mol Genet 2002; 11: 2455-61.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 2455-2461
-
-
Smith, D.J.1
Lusis, A.J.2
-
122
-
-
2342597140
-
A high-density admixture map for disease gene discovery in african americans
-
Smith MW, Patterson N, Lautenberger JA, Truelove AL, McDonald GJ, Waliszewska A, et al. A high-density admixture map for disease gene discovery in african americans. Am J Hum Genet 2004; 74: 1001-13.
-
(2004)
Am J Hum Genet
, vol.74
, pp. 1001-1013
-
-
Smith, M.W.1
Patterson, N.2
Lautenberger, J.A.3
Truelove, A.L.4
McDonald, G.J.5
Waliszewska, A.6
-
123
-
-
34250002140
-
Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor-positive breast cancer
-
Stacey SN, Manolescu A, Sulem P, Rafnar T, Gudmundsson J, Gudjonsson SA, et al. Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor-positive breast cancer. Nat Genet 2007; 39: 865-9.
-
(2007)
Nat Genet
, vol.39
, pp. 865-869
-
-
Stacey, S.N.1
Manolescu, A.2
Sulem, P.3
Rafnar, T.4
Gudmundsson, J.5
Gudjonsson, S.A.6
-
124
-
-
34249828965
-
A variant in CDKAL1 influences insulin response and risk of type 2 diabetes
-
Steinthorsdottir V, Thorleifsson G, Reynisdottir I, Benediktsson R, Jonsdottir T, Walters GB, et al. A variant in CDKAL1 influences insulin response and risk of type 2 diabetes. Nat Genet 2007; 39: 770-5.
-
(2007)
Nat Genet
, vol.39
, pp. 770-775
-
-
Steinthorsdottir, V.1
Thorleifsson, G.2
Reynisdottir, I.3
Benediktsson, R.4
Jonsdottir, T.5
Walters, G.B.6
-
125
-
-
0036255811
-
Opinion: Candidate-gene approaches for studying complex genetic traits: practical considerations
-
Tabor HK, Risch NJ, Myers RM. Opinion: Candidate-gene approaches for studying complex genetic traits: practical considerations. Nat Rev Genet 2002; 3: 391-7.
-
(2002)
Nat Rev Genet
, vol.3
, pp. 391-397
-
-
Tabor, H.K.1
Risch, N.J.2
Myers, R.M.3
-
126
-
-
0017175963
-
Multiple sclerosis and high incidence of a B lymphocyte antigen
-
Terasaki PI, Park MS, Opelz G, Ting A. Multiple sclerosis and high incidence of a B lymphocyte antigen. Science 1976; 193: 1245-7.
-
(1976)
Science
, vol.193
, pp. 1245-1247
-
-
Terasaki, P.I.1
Park, M.S.2
Opelz, G.3
Ting, A.4
-
127
-
-
0041808918
-
Identification of 11 novel and common single nucleotide polymorphisms in the interleukin-7 receptor-alpha gene and their associations with multiple sclerosis
-
Teutsch SM, Booth DR, Bennetts BH, Heard RN, Stewart GJ. Identification of 11 novel and common single nucleotide polymorphisms in the interleukin-7 receptor-alpha gene and their associations with multiple sclerosis. Eur J Hum Genet 2003; 11: 509-15.
-
(2003)
Eur J Hum Genet
, vol.11
, pp. 509-515
-
-
Teutsch, S.M.1
Booth, D.R.2
Bennetts, B.H.3
Heard, R.N.4
Stewart, G.J.5
-
128
-
-
0036277684
-
Point: Population stratification: a problem for case-control studies of candidate-gene associations?
-
Thomas DC, Witte JS. Point: population stratification: a problem for case-control studies of candidate-gene associations? Cancer Epidemiol Biomarkers Prev 2002; 11: 505-12.
-
(2002)
Cancer Epidemiol Biomarkers Prev
, vol.11
, pp. 505-512
-
-
Thomas, D.C.1
Witte, J.S.2
-
129
-
-
0024394725
-
Patients with multiple sclerosis carry DQB1 genes which encode shared polymorphic amino acid sequences
-
Vartdal F, Sollid LM, Vandvik B, Markussen G, Thorsby E. Patients with multiple sclerosis carry DQB1 genes which encode shared polymorphic amino acid sequences. Hum Immunol 1989; 25: 103-10.
-
(1989)
Hum Immunol
, vol.25
, pp. 103-110
-
-
Vartdal, F.1
Sollid, L.M.2
Vandvik, B.3
Markussen, G.4
Thorsby, E.5
-
130
-
-
1642295096
-
Assessing the probability that a positive report is false: An approach for molecular epidemiology studies
-
Wacholder S, Chanock S, Garcia-Closas M, El Ghormli L, Rothman N. Assessing the probability that a positive report is false: an approach for molecular epidemiology studies. J Natl Cancer Inst 2004; 96: 434-42.
-
(2004)
J Natl Cancer Inst
, vol.96
, pp. 434-442
-
-
Wacholder, S.1
Chanock, S.2
Garcia-Closas, M.3
El Ghormli, L.4
Rothman, N.5
-
131
-
-
0043267974
-
Haplotype blocks and linkage disequilibrium in the human genome
-
Wall JD, Pritchard JK. Haplotype blocks and linkage disequilibrium in the human genome. Nat Rev Genet 2003; 4: 587-97.
-
(2003)
Nat Rev Genet
, vol.4
, pp. 587-597
-
-
Wall, J.D.1
Pritchard, J.K.2
-
132
-
-
13144265739
-
Genome-wide association studies: Theoretical and practical concerns
-
Wang WY, Barratt BJ, Clayton DG, Todd JA. Genome-wide association studies: theoretical and practical concerns. Nat Rev Genet 2005; 6: 109-18.
-
(2005)
Nat Rev Genet
, vol.6
, pp. 109-118
-
-
Wang, W.Y.1
Barratt, B.J.2
Clayton, D.G.3
Todd, J.A.4
-
133
-
-
33750876203
-
Combining information from common type 2 diabetes risk polymorphisms improves disease prediction
-
Weedon MN, McCarthy MI, Hitman G, Walker M, Groves CJ, Zeggini E, et al. Combining information from common type 2 diabetes risk polymorphisms improves disease prediction. PLoS Med 2006; 3: e374.
-
(2006)
PLoS Med
, vol.3
-
-
Weedon, M.N.1
McCarthy, M.I.2
Hitman, G.3
Walker, M.4
Groves, C.J.5
Zeggini, E.6
-
134
-
-
84969213492
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
-
Wellcome Trust Case Control Consortium WTCC
-
Wellcome Trust Case Control Consortium (WTCC). Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447: 661-78.
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
-
135
-
-
36448943599
-
A genome-wide scan in forty large pedigrees with multiple sclerosis
-
Willer CJ, Dyment DA, Cherny S, Ramagopalan SV, Herrera BM, Morrison KM, et al. A genome-wide scan in forty large pedigrees with multiple sclerosis. J Hum Genet 2007; 52: 955-62.
-
(2007)
J Hum Genet
, vol.52
, pp. 955-962
-
-
Willer, C.J.1
Dyment, D.A.2
Cherny, S.3
Ramagopalan, S.V.4
Herrera, B.M.5
Morrison, K.M.6
-
136
-
-
0242268416
-
Twin concordance and sibling recurrence rates in multiple sclerosis
-
Willer CJ, Dyment DA, Risch NJ, Sadovnick AD, Ebers GC. Twin concordance and sibling recurrence rates in multiple sclerosis. Proc Natl Acad Sci USA 2003; 100: 12877-82.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 12877-12882
-
-
Willer, C.J.1
Dyment, D.A.2
Risch, N.J.3
Sadovnick, A.D.4
Ebers, G.C.5
-
137
-
-
33745334334
-
Revised diagnostic criteria for neuromyelitis optica
-
Wingerchuk DM, Lennon VA, Pittock SJ, Lucchinetti CF, Weinshenker BG. Revised diagnostic criteria for neuromyelitis optica. Neurology 2006; 66: 1485-9.
-
(2006)
Neurology
, vol.66
, pp. 1485-1489
-
-
Wingerchuk, D.M.1
Lennon, V.A.2
Pittock, S.J.3
Lucchinetti, C.F.4
Weinshenker, B.G.5
-
138
-
-
27544432314
-
How many genes underlie the occurrence of common complex diseases in the population?
-
Yang Q, Khoury MJ, Friedman J, Little J, Flanders WD. How many genes underlie the occurrence of common complex diseases in the population? Int J Epidemiol 2005; 34: 1129-37.
-
(2005)
Int J Epidemiol
, vol.34
, pp. 1129-1137
-
-
Yang, Q.1
Khoury, M.J.2
Friedman, J.3
Little, J.4
Flanders, W.D.5
-
139
-
-
34247548755
-
Genome-wide association study of prostate cancer identifies a second risk locus at 8q24
-
Yeager M, Orr N, Hayes RB, Jacobs KB, Kraft P, Wacholder S, et al. Genome-wide association study of prostate cancer identifies a second risk locus at 8q24. Nat Genet 2007; 39: 645-9.
-
(2007)
Nat Genet
, vol.39
, pp. 645-649
-
-
Yeager, M.1
Orr, N.2
Hayes, R.B.3
Jacobs, K.B.4
Kraft, P.5
Wacholder, S.6
-
140
-
-
34147167634
-
A second major histocompatibility complex susceptibility locus for multiple sclerosis
-
Yeo TW, De Jager PL, Gregory SG, Barcellos LF, Walton A, Goris A, et al. A second major histocompatibility complex susceptibility locus for multiple sclerosis. Ann Neurol 2007; 61: 228-36.
-
(2007)
Ann Neurol
, vol.61
, pp. 228-236
-
-
Yeo, T.W.1
De Jager, P.L.2
Gregory, S.G.3
Barcellos, L.F.4
Walton, A.5
Goris, A.6
-
141
-
-
20144388185
-
Two genes encoding immune-regulatory molecules (LAG3 and IL7R) confer susceptibility to multiple sclerosis
-
Zhang Z, Duvefelt K, Svensson F, Masterman T, Jonasdottir G, Salter H, et al. Two genes encoding immune-regulatory molecules (LAG3 and IL7R) confer susceptibility to multiple sclerosis. Genes Immun 2005; 6: 145-52.
-
(2005)
Genes Immun
, vol.6
, pp. 145-152
-
-
Zhang, Z.1
Duvefelt, K.2
Svensson, F.3
Masterman, T.4
Jonasdottir, G.5
Salter, H.6
|