Negative regulation of virus-triggered IFN-β signaling pathway by alternative splicing of TBK1

Journal of Biological Chemistry

Volumn 283, Issue 51, 2008, Pages 35590-35597

  Deng, Weiwen ^a   Shi, Mude ^a   Han, Meifang ^b   Zhong, Jin ^c   Li, Zhenhu ^a   Li, Weina ^b   Hu, Yu ^a   Yan, Lingchen ^a   Wang, Jie ^a   He, Ying ^c   Tang, Hong ^d   Deubel, Vincent ^b   Luo, Xiaoping ^b   Ning, Qin ^b   Sun, Bing ^a,c,e  

^a INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c INSTITUTE PASTEUR OF SHANGHAI   (China)

^d INSTITUTE OF BIOPHYSICS   (China)

^e E Institute of Immunology   (China)

Author keywords

[No Author keywords available]

Indexed keywords

PIGMENTS;

ALTERNATIVE SPLICING; ANTIVIRAL RESPONSES; IFN SIGNALING; ISOFORM; MOUSE CELLS; NUCLEAR TRANSLOCATIONS; OVEREXPRESSION; PROTEIN KINASES; SENDAI VIRUSES; SIGNALING PATHWAYS;

VIRUSES;

ADAPTOR PROTEIN; BETA INTERFERON; INTERFERON REGULATORY FACTOR 3; PROTEIN KINASE; PROTEIN TBK1; PROTEIN VISA; RETINOIC ACID INDUCIBLE PROTEIN I; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; EXON; GENETIC VARIABILITY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; REGULATORY MECHANISM; SENDAI VIRUS; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ALTERNATIVE SPLICING; ANIMALS; CELL LINE; ENZYME INDUCTION; HUMANS; INTERFERON REGULATORY FACTOR-3; INTERFERON-BETA; MEMBRANE PROTEINS; MICE; NERVE TISSUE PROTEINS; PROTEIN TRANSPORT; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, RETINOIC ACID; RESPIROVIRUS INFECTIONS; SENDAI VIRUS; SIGNAL TRANSDUCTION;

SENDAI VIRUS;

EID: 58149096974     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M805775200     Document Type: Article

References (44)

1. Honda, K., Takaoka, A., and Taniguchi, T. (2006) Immunity 25, 349-360
2. Meylan, E., and Tschopp, J. (2006) Mol. Cell 22, 561-569
3. Alexopoulou, L., Holt, A. C., Medzhitov, R., and Flavell, R. A. (2001) Nature 413, 732-738
4. Diebold, S. S., Kaisho, T., Hemmi, H., Akira, S., and Reise Sousa, C. (2004) Science 303, 1529-1531
5. Heil, F., Hemmi, H., Hochrein, H., Ampenberger, F., Kirschning, C., Akira, S., Lipford, G., Wagner, H., and Bauer, S. (2004) Science 303, 1526-1529
6. Hemmi, H., Takeuchi, O., Kawai, T., Kaisho, T., Sato, S., Sanjo, H., Matsumoto, M., Hoshino, K., Wagner, H., Takeda, K., and Akira, S. (2000) Nature 408, 740-745
7. Yoneyama, M., Kikuchi, M., Natsukawa, T., Shinobu, N., Imaizumi, T., Miyagishi, M., Taira, K., Akira, S., and Fujita, T. (2004) Nat. Immunol. 5, 730-737
8. Kato, H., Takeuchi, O., Sato, S., Yoneyama, M., Yamamoto, M., Matsui, K., Uematsu, S., Jung, A., Kawai, T., Ishii, K. J., Yamaguchi, O., Otsu, K., Tsujimura, T., Koh, C. S., Reis e Sousa, C., Matsuura, Y., Fujita, T., and Akira, S. (2006) Nature 441, 101-105
9. Yamamoto, M., Sato, S., Mori, K., Hoshino, K., Takeuchi, O., Takeda, K., and Akira, S. (2002) J. Immunol. 169, 6668-6672
10. Oshiumi, H., Matsumoto, M., Funami, K., Akazawa, T., and Seya, T. (2003) Nat. Immunol. 4, 161-167
11. Yamamoto, M., Sato, S., Hemmi, H., Hoshino, K., Kaisho, T., Sanjo, H., Takeuchi, O., Sugiyama, M., Okabe, M., Takeda, K., and Akira, S. (2003) Science 301, 640-643
12. Hoebe, K., Du, X., Georgel, P., Janssen, E., Tabeta, K., Kim, S. O., Goode, J., Lin, P., Mann, N., Mudd, S., Crozat, K., Sovath, S., Han, J., and Beutler, B. (2003) Nature 424, 743-748
13. Meylan, E., Curran, J., Hofmann, K., Moradpour, D., Binder, M., Bartenschlager, R., and Tschopp, J. (2005) Nature 437, 1167-1172
14. Xu, L. G., Wang, Y. Y., Han, K. J., Li, L. Y., Zhai, Z., and Shu, H. B. (2005) Mol. Cell 19, 727-740
15. Kawai, T., Takahashi, K., Sato, S., Coban, C., Kumar, H., Kato, H., Ishii, K. J., Takeuchi, O., and Akira, S. (2005) Nat. Immunol. 6, 981-988
16. Seth, R. B., Sun, L., Ea, C. K., and Chen, Z. J. (2005) Cell 122, 669-682
17. Tojima, Y., Fujimoto, A., Delhase, M., Chen, Y., Hatakeyama, S., Nakayama, K., Kaneko, Y., Nimura, Y., Motoyama, N., Ikeda, K., Karin, M., and Nakanishi, M. (2000) Nature 404, 778-782
18. Pomerantz, J. L., and Baltimore, D. (1999) EMBO J. 18, 6694-6704
19. Bonnard, M., Mirtsos, C., Suzuki, S., Graham, K., Huang, J., Ng, M., Itie, A., Wakeham, A., Shahinian, A., Henzel, W. J., Elia, A. J., Shillinglaw, W., Mak, T. W., Cao, Z., and Yeh, W. C. (2000) EMBO J. 19, 4976-4985
20. Fitzgerald, K. A., McWhirter, S. M., Faia, K. L., Rowe, D. C., Latz, E., Golenbock, D. T., Coyle, A. J., Liao, S. M., and Maniatis, T. (2003) Nat. Immunol. 4, 491-496
21. Sharma, S., tenOever, B. R., Grandvaux, N., Zhou, G. P., Lin, R., and Hiscott, J. (2003) Science 300, 1148-1151
22. Hemmi, H., Takeuchi, O., Sato, S., Yamamoto, M., Kaisho, T., Sanjo, H., Kawai, T., Hoshino, K., Takeda, K., and Akira, S. (2004) J. Exp. Med. 199, 1641-1650
23. McWhirter, S. M., Fitzgerald, K. A., Rosains, J., Rowe, D. C., Golenbock, D. T., and Maniatis, T. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 233-238
24. Perry, A. K., Chow, E. K., Goodnough, J. B., Yeh, W. C., and Cheng, G. (2004) J. Exp. Med. 199, 1651-1658
25. Matsui, K., Kumagai, Y., Kato, H., Sato, S., Kawagoe, T., Uematsu, S., Takeuchi, O., and Akira, S. (2006) J. Immunol. 177, 5785-5789
26. Hou, W., Wu, Y., Sun, S., Shi, M., Sun, Y., Yang, C., Pei, G., Gu, Y., Zhong, C., and Sun, B. (2003) J. Immunol. 170, 1728-1736
27. Shi, M., Deng, W., Bi, E., Mao, K., Ji, Y., Lin, G., Wu, X., Tao, Z., Li, Z., Cai, X., Sun, S., Xiang, C., and Sun, B. (2008) Nat. Immunol. 9, 369-377
28. Huang, C., Bi, E., Hu, Y., Deng, W., Tian, Z., Dong, C., Hu, Y., and Sun, B. (2006) J. Immunol. 176, 4173-4181
29. Saito, T., Hirai, R., Loo, Y. M., Owen, D., Johnson, C. L., Sinha, S. C., Akira, S., Fujita, T., and Gale, M., Jr. (2007) Proc. Natl. Acad. Sci. U. S. A. 104, 582-587
30. Venkataraman, T., Valdes, M., Elsby, R., Kakuta, S., Caceres, G., Saijo, S., Iwakura, Y., and Barber, G. N. (2007) J. Immunol. 178, 6444-6455
31. Yoneyama, M., Kikuchi, M., Matsumoto, K., Imaizumi, T., Miyagishi, M., Taira, K., Foy, E., Loo, Y. M., Gale, M., Jr., Akira, S., Yonehara, S., Kato, A., and Fujita, T. (2005) J. Immunol. 175, 2851-2858
32. Rothenfusser, S., Goutagny, N., DiPerna, G., Gong, M., Monks, B. G., Schoenemeyer, A., Yamamoto, M., Akira, S., and Fitzgerald, K. A. (2005) J. Immunol. 175, 5260-5268
33. Arimoto, K., Takahashi, H., Hishiki, T., Konishi, H., Fujita, T., and Shimotohno, K. (2007) Proc. Natl. Acad. Sci. U. S. A. 104, 7500-7505
34. Karpova, A. Y., Howley, P. M., and Ronco, L. V. (2000) Genes Dev. 14, 2813-2818
35. Mancl, M. E., Hu, G., Sangster-Guity, N., Olshalsky, S. L., Hoops, K., Fitzgerald-Bocarsly, P., Pitha, P. M., Pinder, K., and Barnes, B. J. (2005) J. Biol. Chem. 280, 21078-21090
36. Martin, H. J., Lee, J. M., Walls, D., and Hayward, S. D. (2007) J. Virol. 81, 9748-9758
37. Lee, E. J., Jo, M., Park, J., Zhang, W., and Lee, J. H. (2006) Biochem. Biophys. Res. Commun. 347, 882-888
38. Karpova, A. Y., Ronco, L. V., and Howley, P. M. (2001) Mol. Cell. Biol. 21, 4169-4176
39. Zhang, L., and Pagano, J. S. (1997) Mol. Cell. Biol. 17, 5748-5757
40. Vilasco, M., Larrea, E., Vitour, D., Dabo, S., Breiman, A., Regnault, B., Riezu, J. I., Eid, P., Prieto, J., and Meurs, E. F. (2006) Hepatology 44, 1635-1647
41. Gack, M. U., Shin, Y. C., Joo, C. H., Urano, T., Liang, C., Sun, L., Takeuchi, O., Akira, S., Chen, Z., Inoue, S., and Jung, J. U. (2007) Nature 446, 916-920
42. Janssens, S., Burns, K., Vercammen, E., Tschopp, J., and Beyaert, R. (2003) FEBS Lett. 548, 103-107
43. Burns, K., Janssens, S., Brissoni, B., Olivos, N., Beyaert, R., and Tschopp, J. (2003) J. Exp. Med. 197, 263-268
44. Janssens, S., Burns, K., Tschopp, J., and Beyaert, R. (2002) Curr. Biol. 12, 467-471