Deficiency of T2K leads to apoptotic liver degeneration and impaired NF-κB-dependent gene transcription

EMBO Journal

Volumn 19, Issue 18, 2000, Pages 4976-4985

  Bonnard, Madeleine ^a   Mirtsos, Christine ^a   Suzuki, Shinobu ^a   Graham, Kevin ^a   Huang, Jianing ^b   Ng, Michelle ^a   Itié, Annick ^a   Wakeham, Andrew ^a   Shahinian, Arda ^a   Henzel, William J ^c   Elia, Andrew J ^a   Shillinglaw, Wendy ^c   Mak, Tak W ^a   Cao, Zhaodan ^b   Yeh, Wen Chen ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b AMGEN INC   (United States)

^c GENENTECH INC   (United States)

Author keywords

Apoptosis; I B kinase; NF B; T2K; TNF signaling

Indexed keywords

CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DEGENERATION; FIBROBLAST; GENETIC TRANSCRIPTION; HETEROZYGOTE; LIVER DISEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; THYMOCYTE;

AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; BLOTTING, SOUTHERN; CYCLOHEXIMIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FIBROBLASTS; FLOW CYTOMETRY; GENE TARGETING; GENES, REPORTER; GENOTYPE; HETEROZYGOTE; I-KAPPA B KINASE; IN SITU NICK-END LABELING; INTERLEUKIN-1; LIGASES; LIVER; LYMPHOCYTES; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; NF-KAPPA B; PHOSPHORYLATION; PRECIPITIN TESTS; PROTEIN BINDING; PROTEIN SYNTHESIS INHIBITORS; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; RECOMBINANT PROTEINS; THYMUS GLAND; TIME FACTORS; TNF RECEPTOR-ASSOCIATED FACTOR 2; TRANSCRIPTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA;

EID: 0034665047     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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