Hypoxia-inducible factor 1α under rapid enzymatic hypoxia: Cells sense decrements of oxygen but not hypoxia per se

Free Radical Biology and Medicine

Volumn 46, Issue 2, 2009, Pages 182-191

  Millonig, Gunda ^a,b   Hegedüsch, Stephan ^b   Becker, Laren ^a   Seitz, Helmut Karl ^b   Schuppan, Detlef ^a   Mueller, Sebastian ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Catalase; Feedback loop; Free radicals; Glucose oxidase; H2O2; HIF1; Hypoxia; Oxygen sensing; PHD

Indexed keywords

CATALASE; GLUCOSE OXIDASE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; OXYGEN; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE;

ARTICLE; CELL SURVIVAL; ENZYME ACTIVITY; GENE; HUMAN; HUMAN CELL; HYPOXIA; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION;

ANOXIA; CATALASE; CELL LINE; DIOXYGENASES; DNA-BINDING PROTEINS; FEEDBACK, BIOCHEMICAL; GLUCOSE OXIDASE; HUMANS; HYDROGEN PEROXIDE; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; OXYGEN COMPOUNDS; PROCOLLAGEN-PROLINE DIOXYGENASE; PROTEIN BINDING; PROTEIN CONFORMATION; RNA, SMALL INTERFERING; TRANSCRIPTION FACTORS;

MAMMALIA;

EID: 58049194159     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2008.09.043     Document Type: Article

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