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Volumn 4, Issue 4, 2008, Pages 215-227

Engineering vascularized tissues using natural and synthetic small molecules

Author keywords

Angiogenesis; Arteriogenesis; Drug discovery; Ischemic tissue disease; Neovascularization; Small molecule; Tissue engineering; Vascular development

Indexed keywords

2 AMINO 2 (3 OCTYLPHENYLCARBAMOYL)ETHYL PHOSPHATE; 4 (2,6 DICHLORO 4 PYRIDINYL) 1 (1,3 DIMETHYL 4 ISOPROPYL 1H PYRAZOLO[3,4 B]PYRIDIN 6 YL)SEMICARBAZIDE; 5 (4 PHENYL 5 TRIFLUOROMETHYL 2 THIENYL) 3 (3 TRIFLUOROMETHYLPHENYL) 1,2,4 OXADIAZOLE; ADENOSINE; ADENOVIRUS VECTOR; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; ANGIOPOIETIN 1; AUTOTAXIN; BAICALEIN; CICLOPIROXOLAMINE; COBALT CHLORIDE; CURCUMIN; DEFEROXAMINE; DIBENZOYLMETHANE DERIVATIVE; FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR 4; FINGOLIMOD; GINSENOSIDE RB 1; HYPOXIA INDUCIBLE FACTOR 1; KI 16425; LYSOPHOSPHATIDIC ACID; PLATELET DERIVED GROWTH FACTOR; PROTOCATECHUIC ACID; RESVERATROL; SOKOTRASTEROL SULFATE; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; STEROID; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; UNINDEXED DRUG; VASCULOTROPIN 121; VASCULOTROPIN 165; VPC 01091; VPC 12249; VPC 25239; VPC 31143; VPC 32183; VPC 44116; W 146;

EID: 57349187857     PISSN: 15476278     EISSN: 15558592     Source Type: Journal    
DOI: 10.4161/org.4.4.6963     Document Type: Review
Times cited : (25)

References (163)
  • 1
    • 0034076189 scopus 로고    scopus 로고
    • Mechanisms of angiogenesis and arteriogenesis
    • Carmeliet P. Mechanisms of angiogenesis and arteriogenesis. Nat Med 2000; 6:389-95.
    • (2000) Nat Med , vol.6 , pp. 389-395
    • Carmeliet, P.1
  • 2
    • 0347117510 scopus 로고    scopus 로고
    • Microvascular remodeling: A complex continuum spanning angiogenesis to arteriogenesis
    • Peirce SM, Skalak TC. Microvascular remodeling: a complex continuum spanning angiogenesis to arteriogenesis. Microcirculation 2003; 10:99-111.
    • (2003) Microcirculation , vol.10 , pp. 99-111
    • Peirce, S.M.1    Skalak, T.C.2
  • 3
    • 33847287710 scopus 로고    scopus 로고
    • Insights into pathways of arteriogenesis
    • Heil M, Schaper W. Insights into pathways of arteriogenesis. Current Pharm. Biotech 2007; 8:35-42.
    • (2007) Current Pharm. Biotech , vol.8 , pp. 35-42
    • Heil, M.1    Schaper, W.2
  • 4
    • 0030721619 scopus 로고    scopus 로고
    • Pharmacodynamics of basic fibroblast growth factor: Route of administration determines myocardial and systemic distribution
    • Lazarous DF, Shou M, Stiber JA, Dadhania DM, Thirumurti V, Hodge E, et al. Pharmacodynamics of basic fibroblast growth factor: route of administration determines myocardial and systemic distribution. Cardiovasc Res 1997; 36:78-85.
    • (1997) Cardiovasc Res , vol.36 , pp. 78-85
    • Lazarous, D.F.1    Shou, M.2    Stiber, J.A.3    Dadhania, D.M.4    Thirumurti, V.5    Hodge, E.6
  • 5
    • 33748191608 scopus 로고    scopus 로고
    • Growth factor-induced therapeutic neovascularization for ischaemic vascular disease: Time for a re-evaluation?
    • Lekas M, Lekas P, Latter DA, Kutryk MB, Stewart DJ. Growth factor-induced therapeutic neovascularization for ischaemic vascular disease: time for a re-evaluation? Curr Opin Cardiol 2006; 21:376-84.
    • (2006) Curr Opin Cardiol , vol.21 , pp. 376-384
    • Lekas, M.1    Lekas, P.2    Latter, D.A.3    Kutryk, M.B.4    Stewart, D.J.5
  • 6
    • 0028344109 scopus 로고
    • Therapeutic angiogenesis - a single intraarterial bolus of vascular endothelial growth-factor augments revascularization in a rabbit ischemic hind-limb
    • Takeshita S, Zheng LP, Brogi E, Kearney M, Pu LQ, Bunting S, et al. Therapeutic angiogenesis - a single intraarterial bolus of vascular endothelial growth-factor augments revascularization in a rabbit ischemic hind-limb. J Clin Invest 1994; 93:662-70.
    • (1994) J Clin Invest , vol.93 , pp. 662-670
    • Takeshita, S.1    Zheng, L.P.2    Brogi, E.3    Kearney, M.4    Pu, L.Q.5    Bunting, S.6
  • 7
    • 1342346686 scopus 로고    scopus 로고
    • Spatial and temporal control of angiogenesis and arterialization using focal applications of VEGF164 and Ang-1
    • Peirce SM, Price RJ, Skalak TC. Spatial and temporal control of angiogenesis and arterialization using focal applications of VEGF164 and Ang-1. Am J Physiol Heart Circ Physiol 2004a; 286:918-25.
    • (2004) Am J Physiol Heart Circ Physiol , vol.286 , pp. 918-925
    • Peirce, S.M.1    Price, R.J.2    Skalak, T.C.3
  • 8
    • 0038376002 scopus 로고    scopus 로고
    • Molecular regulation of vessel maturation
    • Jain RK. Molecular regulation of vessel maturation. Nature Medicine 2003; 9:685-93.
    • (2003) Nature Medicine , vol.9 , pp. 685-693
    • Jain, R.K.1
  • 9
    • 33846050010 scopus 로고    scopus 로고
    • Spatio-temporal VEGF and PDGF delivery patterns blood vessel formation and maturation
    • Chen RR, Silva EA, Yuen WW, Mooney DJ. Spatio-temporal VEGF and PDGF delivery patterns blood vessel formation and maturation. Pharm Res 2007; 24:258-64.
    • (2007) Pharm Res , vol.24 , pp. 258-264
    • Chen, R.R.1    Silva, E.A.2    Yuen, W.W.3    Mooney, D.J.4
  • 10
  • 11
    • 26844545316 scopus 로고    scopus 로고
    • Integrated recombinant protein expression and purification platform based on ralstonia eutropha
    • Barnard GC, McCool JD, Wood DW, Gerngross TU. Integrated recombinant protein expression and purification platform based on ralstonia eutropha. Appl Environ Microbiol 2005; 71:5735-42.
    • (2005) Appl Environ Microbiol , vol.71 , pp. 5735-5742
    • Barnard, G.C.1    McCool, J.D.2    Wood, D.W.3    Gerngross, T.U.4
  • 12
    • 0035917313 scopus 로고    scopus 로고
    • HIF alpha targeted for VHL-mediated destruction by proline hydroxylation: Implications for O-2 sensing
    • Ivan M, Kondo K, Yang HF, Kim W, Valiando J, Ohh M, et al. HIF alpha targeted for VHL-mediated destruction by proline hydroxylation: Implications for O-2 sensing. Science 2001; 292:464-68.
    • (2001) Science , vol.292 , pp. 464-468
    • Ivan, M.1    Kondo, K.2    Yang, H.F.3    Kim, W.4    Valiando, J.5    Ohh, M.6
  • 13
    • 0035887011 scopus 로고    scopus 로고
    • FIH-1: A novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity
    • Mahon PC, Hirota K, Semenza GL. FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity. Genes Dev 2001; 15:2675-86.
    • (2001) Genes Dev , vol.15 , pp. 2675-2686
    • Mahon, P.C.1    Hirota, K.2    Semenza, G.L.3
  • 14
    • 0344874751 scopus 로고    scopus 로고
    • Cell type-specific regulation of angiogenic growth factor gene expression and induction of angiogenesis in nonischemic tissue by a constitutively active form of hypoxia-inducible factor 1
    • Kelly BD, Hackett SF, Hirota K, Oshima Y, Cai Z, Berg-Dixon S, et al. Cell type-specific regulation of angiogenic growth factor gene expression and induction of angiogenesis in nonischemic tissue by a constitutively active form of hypoxia-inducible factor 1. Circ Res 2003; 93:1074-81.
    • (2003) Circ Res , vol.93 , pp. 1074-1081
    • Kelly, B.D.1    Hackett, S.F.2    Hirota, K.3    Oshima, Y.4    Cai, Z.5    Berg-Dixon, S.6
  • 15
    • 0034641624 scopus 로고    scopus 로고
    • Clinical trials in coronary angiogenesis: Issues, problems, consensus: an expert panel summary
    • Simons M, Bonow RO, Chronos NA, Cohen DJ, Giordano FJ, Hammond HK, et al. Clinical trials in coronary angiogenesis: issues, problems, consensus: an expert panel summary. Circulation 2000; 102:73-86.
    • (2000) Circulation , vol.102 , pp. 73-86
    • Simons, M.1    Bonow, R.O.2    Chronos, N.A.3    Cohen, D.J.4    Giordano, F.J.5    Hammond, H.K.6
  • 16
    • 0033562569 scopus 로고    scopus 로고
    • Defective vascularization of HiF-1α-null embryos is not associated with VEGF deficiency but with mesenchymal cell death
    • Kotch LE, Iyer NV, Laughner E, Semenza GL. Defective vascularization of HiF-1α-null embryos is not associated with VEGF deficiency but with mesenchymal cell death. Develop Biol 1999; 209:254-67.
    • (1999) Develop Biol , vol.209 , pp. 254-267
    • Kotch, L.E.1    Iyer, N.V.2    Laughner, E.3    Semenza, G.L.4
  • 17
    • 0035476509 scopus 로고    scopus 로고
    • Induction of hypervascularity without leakage or inflammation in transgenic mice overexpressing hypoxia-inducible factor-1α
    • Elson DA, Thurston G, Huang LE, Ginzinger DG, McDonald DM, Johnson RS, et al. Induction of hypervascularity without leakage or inflammation in transgenic mice overexpressing hypoxia-inducible factor-1α. Genes Dev 2001; 15:2520-32.
    • (2001) Genes Dev , vol.15 , pp. 2520-2532
    • Elson, D.A.1    Thurston, G.2    Huang, L.E.3    Ginzinger, D.G.4    McDonald, D.M.5    Johnson, R.S.6
  • 18
    • 0036275028 scopus 로고    scopus 로고
    • Intramyocardial injection of naked DNA encoding HIF-1alpha/VP16 hybrid to enhance angiogenesis in an acute myocardial infarction model in the rat
    • Shyu KG, Wang MT, Wang BW, et al. Intramyocardial injection of naked DNA encoding HIF-1alpha/VP16 hybrid to enhance angiogenesis in an acute myocardial infarction model in the rat. Cardiovasc Res 2000; 54:576-83.
    • (2000) Cardiovasc Res , vol.54 , pp. 576-583
    • Shyu, K.G.1    Wang, M.T.2    Wang, B.W.3
  • 19
    • 0034739533 scopus 로고    scopus 로고
    • Angiogenesis is induced in a rabbit model of hindlimb ischemia by naked DNA encoding an HIF-1α/VP16 hybrid transcription factor
    • Vincent KA, Shyu KG, Luo Y, Magner M, Tio RA, Jiang C, et al. Angiogenesis is induced in a rabbit model of hindlimb ischemia by naked DNA encoding an HIF-1α/VP16 hybrid transcription factor. Circulation 2000; 102:2255-61.
    • (2000) Circulation , vol.102 , pp. 2255-2261
    • Vincent, K.A.1    Shyu, K.G.2    Luo, Y.3    Magner, M.4    Tio, R.A.5    Jiang, C.6
  • 20
    • 0038380470 scopus 로고    scopus 로고
    • Activation of the hypoxia-inducible factor-pathway and stimulation of angiogenesis by application of prolyl hydroxylase inhibitors
    • Warnecke C, Griethe W, Weidemann A, Jurgensen JS, William C, Bachmann S, et al. Activation of the hypoxia-inducible factor-pathway and stimulation of angiogenesis by application of prolyl hydroxylase inhibitors. FASEB J 2003; 17:1186-8.
    • (2003) FASEB J , vol.17 , pp. 1186-1188
    • Warnecke, C.1    Griethe, W.2    Weidemann, A.3    Jurgensen, J.S.4    William, C.5    Bachmann, S.6
  • 21
    • 0031903668 scopus 로고    scopus 로고
    • Effect of the β-diketones diferuloulmethane (curcumin) and dibenzoylmethane on rat mammary DNA adducts and tumors induced by 7,12-dimethylbenz[a]anthracene
    • Singletary K, MacDonald C, Iovinelli M, Fisher C, Wallig M. Effect of the β-diketones diferuloulmethane (curcumin) and dibenzoylmethane on rat mammary DNA adducts and tumors induced by 7,12-dimethylbenz[a]anthracene. Carcinogenesis 1998; 19:1039-43.
    • (1998) Carcinogenesis , vol.19 , pp. 1039-1043
    • Singletary, K.1    MacDonald, C.2    Iovinelli, M.3    Fisher, C.4    Wallig, M.5
  • 23
    • 0037390915 scopus 로고    scopus 로고
    • The antimycotic ciclopirox olamine induces HIF-1alpha stability, VEGF expression and angiogenesis
    • Linden T, Katschinski DM, Eckhardt K, Scheid A, Pagel H, Wenger RH. The antimycotic ciclopirox olamine induces HIF-1alpha stability, VEGF expression and angiogenesis. FASEB J 2003; 17:761-3.
    • (2003) FASEB J , vol.17 , pp. 761-763
    • Linden, T.1    Katschinski, D.M.2    Eckhardt, K.3    Scheid, A.4    Pagel, H.5    Wenger, R.H.6
  • 24
    • 0028843411 scopus 로고
    • Regulation of angiogenic growth factor expression by hypoxia, transition metals and chelating agents
    • Gleadle JM, Ebert BL, Firth JD, Ratcliffe PJ. Regulation of angiogenic growth factor expression by hypoxia, transition metals and chelating agents. Am J Physiol 1995; 268:1362-8.
    • (1995) Am J Physiol , vol.268 , pp. 1362-1368
    • Gleadle, J.M.1    Ebert, B.L.2    Firth, J.D.3    Ratcliffe, P.J.4
  • 25
    • 0027136260 scopus 로고
    • Desferrioxamine induces erythropoietin gene expression and hypoxia-inducible factor 1 DNA-binding activity: Implications for models of hypoxia signal transduction
    • Wang GL and Semenza GL. Desferrioxamine induces erythropoietin gene expression and hypoxia-inducible factor 1 DNA-binding activity: implications for models of hypoxia signal transduction. Blood 1993; 82:3610-5.
    • (1993) Blood , vol.82 , pp. 3610-3615
    • Wang, G.L.1    Semenza, G.L.2
  • 26
    • 0037232582 scopus 로고    scopus 로고
    • Deferoxamine enhances neovascularization and recovery of ischemic skeletal muscle in an experimental sheep model
    • Chekanov VS, Nikolaychik V, Maternowski MA, Mehran R, Leon MB, Adamian M, et al. Deferoxamine enhances neovascularization and recovery of ischemic skeletal muscle in an experimental sheep model. Ann Thorac Surg 1003; 75:184-9.
    • Ann Thorac Surg , vol.1003 , Issue.75 , pp. 184-189
    • Chekanov, V.S.1    Nikolaychik, V.2    Maternowski, M.A.3    Mehran, R.4    Leon, M.B.5    Adamian, M.6
  • 27
    • 38649128127 scopus 로고    scopus 로고
    • Activation of the hypoxia-inducible factor-1α pathway accelerates bone regeneration
    • Wan C, Gilbert SR, Wang Y, Cao X, Shen X, Ramaswamy G, et al. Activation of the hypoxia-inducible factor-1α pathway accelerates bone regeneration. Proc Natl Acad Sci USA 2008; 105:686-91.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 686-691
    • Wan, C.1    Gilbert, S.R.2    Wang, Y.3    Cao, X.4    Shen, X.5    Ramaswamy, G.6
  • 29
    • 0027210562 scopus 로고
    • General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia
    • Wang GL and Semenza GL. General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia. Proc Natl Acad Sci USA 1993; 90:4304-8.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 4304-4308
    • Wang, G.L.1    Semenza, G.L.2
  • 30
    • 3142523739 scopus 로고    scopus 로고
    • HIF-1: An oxygen and metal responsive transcription factor
    • Maxwell P and Salnikow K. HIF-1: An oxygen and metal responsive transcription factor. Cancer Biol Ther 2004; 3:29-35.
    • (2004) Cancer Biol Ther , vol.3 , pp. 29-35
    • Maxwell, P.1    Salnikow, K.2
  • 31
    • 25144475141 scopus 로고    scopus 로고
    • Cobalt promotes angiogenesis via hypoxia-inducible factor and protects tubulointerstitium in the remnant kidney model
    • Tanaka T, Kojima I, Ohse T, Ingelfinger JR, Adler S, Fujita T, et al. Cobalt promotes angiogenesis via hypoxia-inducible factor and protects tubulointerstitium in the remnant kidney model. Lab Invest 2005; 85:1292-307.
    • (2005) Lab Invest , vol.85 , pp. 1292-1307
    • Tanaka, T.1    Kojima, I.2    Ohse, T.3    Ingelfinger, J.R.4    Adler, S.5    Fujita, T.6
  • 32
    • 27744556130 scopus 로고    scopus 로고
    • Heme oxygenase-1-dependent and -independent regulation of angiogenic genes expression: Effect of cobalt protoporphyrin and cobalt chloride on VEGF and IL-8 synthesis in human microvascular endothelial cells
    • Loboda A, Jazwa A, Wegiel B, Jozkowicz A, Dulak J. Heme oxygenase-1-dependent and -independent regulation of angiogenic genes expression: effect of cobalt protoporphyrin and cobalt chloride on VEGF and IL-8 synthesis in human microvascular endothelial cells. Cell Mol Biol 2005; 51:347-55.
    • (2005) Cell Mol Biol , vol.51 , pp. 347-355
    • Loboda, A.1    Jazwa, A.2    Wegiel, B.3    Jozkowicz, A.4    Dulak, J.5
  • 33
    • 9344262366 scopus 로고    scopus 로고
    • Cobalt chloride induces delayed cardiac preconditioning in mcie through selective activation of HIF-1α and AP-1 and iNOS signaling
    • Xi L, Taher M, Yin C, Salloum F, Kukreja RC. Cobalt chloride induces delayed cardiac preconditioning in mcie through selective activation of HIF-1α and AP-1 and iNOS signaling. Am J Physiol Heart Circ Physiol 2004; 287:2369-75.
    • (2004) Am J Physiol Heart Circ Physiol , vol.287 , pp. 2369-2375
    • Xi, L.1    Taher, M.2    Yin, C.3    Salloum, F.4    Kukreja, R.C.5
  • 34
    • 0031037762 scopus 로고    scopus 로고
    • Increased tolerance of chronically hypoxic immature heart to ischemia. Contribution of the KATP channel
    • Baker JE, Curry BD, Olinger GN, Gross GJ. Increased tolerance of chronically hypoxic immature heart to ischemia. Contribution of the KATP channel. Circulation 1997; 95:1278-85.
    • (1997) Circulation , vol.95 , pp. 1278-1285
    • Baker, J.E.1    Curry, B.D.2    Olinger, G.N.3    Gross, G.J.4
  • 35
    • 0035662110 scopus 로고    scopus 로고
    • Cardiac function, microvascular structure and capillary hematocrit in hearts of polycythemic rats
    • Rakusan K, Cicutti N, Kolar F. Cardiac function, microvascular structure and capillary hematocrit in hearts of polycythemic rats. Am J Physiol Heart Circ Physiol 2001; 281:2425-31.
    • (2001) Am J Physiol Heart Circ Physiol , vol.281 , pp. 2425-2431
    • Rakusan, K.1    Cicutti, N.2    Kolar, F.3
  • 36
    • 0037108807 scopus 로고    scopus 로고
    • Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxlyase acting on hypoxia-inducible factor
    • Ivan M, Haberberger T, Gervasi DC, Michelson KS, Gunzler V, Kondo K, et al. Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxlyase acting on hypoxia-inducible factor. Proc Natl Acad Sci USA 2002; 99:13459-64.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 13459-13464
    • Ivan, M.1    Haberberger, T.2    Gervasi, D.C.3    Michelson, K.S.4    Gunzler, V.5    Kondo, K.6
  • 37
    • 45749108208 scopus 로고    scopus 로고
    • Baicalein induces functional hypoxiainducible factor-1α and angiogenesis
    • Cho H, Lee H, Ahn D, Kim SY, Kim S, Lee KB, et al. Baicalein induces functional hypoxiainducible factor-1α and angiogenesis. Mol Pharmacol 2008; 74:70-81.
    • (2008) Mol Pharmacol , vol.74 , pp. 70-81
    • Cho, H.1    Lee, H.2    Ahn, D.3    Kim, S.Y.4    Kim, S.5    Lee, K.B.6
  • 38
    • 0036667557 scopus 로고    scopus 로고
    • A novel iron chelator that does not induce HIF-1 activity
    • Creighton-Gutteridge M and Tyrrell RM. A novel iron chelator that does not induce HIF-1 activity. Free Radic Biol Med 2002; 33:356-63.
    • (2002) Free Radic Biol Med , vol.33 , pp. 356-363
    • Creighton-Gutteridge, M.1    Tyrrell, R.M.2
  • 40
    • 0020488069 scopus 로고
    • A stereochemical concept for the catalytic mechanism of prolylhydroxylase: Applicability to classification and design of inhibitors
    • Hanauske-Abel HM and Gunzler V. A stereochemical concept for the catalytic mechanism of prolylhydroxylase: applicability to classification and design of inhibitors. J Theor Biol 1982; 94:421-55.
    • (1982) J Theor Biol , vol.94 , pp. 421-455
    • Hanauske-Abel, H.M.1    Gunzler, V.2
  • 41
    • 0035917808 scopus 로고    scopus 로고
    • Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
    • Jaakkola P, Mole Dr, Tian YM, Wilson MI, Gielbert J, Gaskell SJ, et al. Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation. Science 2001; 292:468-72.
    • (2001) Science , vol.292 , pp. 468-472
    • Jaakkola, P.1    Mole, D.2    Tian, Y.M.3    Wilson, M.I.4    Gielbert, J.5    Gaskell, S.J.6
  • 42
    • 15244342671 scopus 로고    scopus 로고
    • Stimulation of HIF-1α, HIF-2α and VEGF by prolyl 4-hydroxylase inhibition in human lung endothelial and epithelial cells
    • Asikainen TM, Ahmad A, Schneider BK, Ho WB, Arend M, Brenner M, et al. Stimulation of HIF-1α, HIF-2α and VEGF by prolyl 4-hydroxylase inhibition in human lung endothelial and epithelial cells. Free Radic Biol Med 2005; 38:1002-13.
    • (2005) Free Radic Biol Med , vol.38 , pp. 1002-1013
    • Asikainen, T.M.1    Ahmad, A.2    Schneider, B.K.3    Ho, W.B.4    Arend, M.5    Brenner, M.6
  • 43
    • 23744443462 scopus 로고    scopus 로고
    • HIF-1 activation attenuates postischemic myocardial injury: Role for heme oxygenase-1 in modulating microvascular chemokine generation
    • Okaili R, Natarajan R, Salloum F, Fisher BJ, Jones D, Fowler AA, III, et al. HIF-1 activation attenuates postischemic myocardial injury: role for heme oxygenase-1 in modulating microvascular chemokine generation. Am J Physiol Heart Circ Physiol 2005; 289:542-8.
    • (2005) Am J Physiol Heart Circ Physiol , vol.289 , pp. 542-548
    • Okaili, R.1    Natarajan, R.2    Salloum, F.3    Fisher, B.J.4    Jones, D.5    Fowler III, A.A.6
  • 44
    • 6444242574 scopus 로고    scopus 로고
    • Milkiewicz M, Pugh CW, Egginton S. Inhibition of endogenous HIF inactivation induces angiogenesis in ischaemic skeletal muscles of mice. J Physiol 2004; 560.1:21-6.
    • Milkiewicz M, Pugh CW, Egginton S. Inhibition of endogenous HIF inactivation induces angiogenesis in ischaemic skeletal muscles of mice. J Physiol 2004; 560.1:21-6.
  • 45
    • 0141992249 scopus 로고    scopus 로고
    • Differential expression of Flk-1 and Flt-1 in rat skeletal muscle in reponse to chronic ischaemia:favourable effect of muscel activity
    • Milkiewicz M, Hudlicka O, Verhaeg J, Egginton S, Brown MD. Differential expression of Flk-1 and Flt-1 in rat skeletal muscle in reponse to chronic ischaemia:favourable effect of muscel activity. Clin Sci (Lond) 2003; 105:473-82.
    • (2003) Clin Sci (Lond) , vol.105 , pp. 473-482
    • Milkiewicz, M.1    Hudlicka, O.2    Verhaeg, J.3    Egginton, S.4    Brown, M.D.5
  • 47
    • 33646531437 scopus 로고    scopus 로고
    • G proteins in drug screening: From analysis of receptor-G protein specificity to manipulation of GPCR-mediated signaling pathways
    • Kostenis E. G proteins in drug screening: From analysis of receptor-G protein specificity to manipulation of GPCR-mediated signaling pathways. Curr Pharma Design 2006; 12:1703-15.
    • (2006) Curr Pharma Design , vol.12 , pp. 1703-1715
    • Kostenis, E.1
  • 48
    • 32044448106 scopus 로고    scopus 로고
    • Emerging medicinal roles for lysophospholipid signaling
    • Gardell SE, Dubin AE, Chun J. Emerging medicinal roles for lysophospholipid signaling. Trends Mol Med 2006; 12:65-75.
    • (2006) Trends Mol Med , vol.12 , pp. 65-75
    • Gardell, S.E.1    Dubin, A.E.2    Chun, J.3
  • 49
    • 11144246968 scopus 로고    scopus 로고
    • GPCR deorphanizations: The novel, the known, and the unexpected transmitter
    • Civelli O. GPCR deorphanizations: the novel, the known, and the unexpected transmitter. Trends Pharmacol Sci 2005; 26:15-9.
    • (2005) Trends Pharmacol Sci , vol.26 , pp. 15-19
    • Civelli, O.1
  • 50
  • 51
    • 0029948396 scopus 로고    scopus 로고
    • Suppression of ceramide-mediated programmed cell death by sphingosine 1-phosphate
    • Culliver O, Pirianov G, Kleuser B, Vanek PG, Coso OA, Gutkind S, et al. Suppression of ceramide-mediated programmed cell death by sphingosine 1-phosphate. Nature 1996; 381:800-3.
    • (1996) Nature , vol.381 , pp. 800-803
    • Culliver, O.1    Pirianov, G.2    Kleuser, B.3    Vanek, P.G.4    Coso, O.A.5    Gutkind, S.6
  • 52
    • 17944363486 scopus 로고    scopus 로고
    • Akt-mediated phosphorylation of the G protein-coupled receptor EDG-1 is required for endothelial cell chemotaxis
    • Lee MJ, Thangada S, Paik JH, Sapkota GP, Ancellin N, Chae SS, et al. Akt-mediated phosphorylation of the G protein-coupled receptor EDG-1 is required for endothelial cell chemotaxis. Mol Cell 2001; 8:693-704.
    • (2001) Mol Cell , vol.8 , pp. 693-704
    • Lee, M.J.1    Thangada, S.2    Paik, J.H.3    Sapkota, G.P.4    Ancellin, N.5    Chae, S.S.6
  • 53
    • 0035196711 scopus 로고    scopus 로고
    • EDG-1 links the PDGF receptor to Src and focal adhesion kinase activation leading to lamellipodia formation and cell migration
    • Rosenfeldt HM, Hobson JP, Maceyka M, Olivera A, Nava VE, Milstein S, et al. EDG-1 links the PDGF receptor to Src and focal adhesion kinase activation leading to lamellipodia formation and cell migration. FASEB J 2001; 15:2649-59.
    • (2001) FASEB J , vol.15 , pp. 2649-2659
    • Rosenfeldt, H.M.1    Hobson, J.P.2    Maceyka, M.3    Olivera, A.4    Nava, V.E.5    Milstein, S.6
  • 54
    • 0037370012 scopus 로고    scopus 로고
    • i pathways integrated downstream of a single G protein-coupled sphingosine 1-phosphate receptor isoform
    • i pathways integrated downstream of a single G protein-coupled sphingosine 1-phosphate receptor isoform. Mol Cell Biol 2003; 23:1534-45.
    • (2003) Mol Cell Biol , vol.23 , pp. 1534-1545
    • Sugimoto, N.1    Takuwa, N.2    Okamoto, H.3    Sakurada, S.4    Takuwa, Y.5
  • 56
    • 0033783522 scopus 로고    scopus 로고
    • Edg-1, the G protein-coupled receptor for sphingosine 1-phosphate, is essential for vascular maturation
    • Liu Y, Wada R, Yamashita T, Mi Y, Deng CX, Hobson JP, et al. Edg-1, the G protein-coupled receptor for sphingosine 1-phosphate, is essential for vascular maturation. J Clin Invest 2000b; 106:951-61.
    • (2000) J Clin Invest , vol.106 , pp. 951-961
    • Liu, Y.1    Wada, R.2    Yamashita, T.3    Mi, Y.4    Deng, C.X.5    Hobson, J.P.6
  • 57
    • 17644365138 scopus 로고    scopus 로고
    • Chemokines, sphingosine 1-phosphate, and cell migration in secondary lymphoid organs
    • Cyster JG. Chemokines, sphingosine 1-phosphate, and cell migration in secondary lymphoid organs. Annu Rev Immunol 2005; 23:127-59.
    • (2005) Annu Rev Immunol , vol.23 , pp. 127-159
    • Cyster, J.G.1
  • 58
    • 0034522434 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate signaling via the endothelial differentiation gene family of G protein-coupled receptors
    • Pyne S and Pyne N. Sphingosine 1-phosphate signaling via the endothelial differentiation gene family of G protein-coupled receptors. Pharmacol Ther 2000; 88:115-31.
    • (2000) Pharmacol Ther , vol.88 , pp. 115-131
    • Pyne, S.1    Pyne, N.2
  • 59
    • 0034658614 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate stimulates proliferation and migration of human endothelial cells possibly through the lipid receptors, Edg-1 and Edg-3
    • Kimura T, Watanabe T, Sato K, Kon J, Tomura H, Tamama K, et al. Sphingosine 1-phosphate stimulates proliferation and migration of human endothelial cells possibly through the lipid receptors, Edg-1 and Edg-3. Biochem J 2000; 348:71-6.
    • (2000) Biochem J , vol.348 , pp. 71-76
    • Kimura, T.1    Watanabe, T.2    Sato, K.3    Kon, J.4    Tomura, H.5    Tamama, K.6
  • 60
    • 0035860831 scopus 로고    scopus 로고
    • Role of the sphingosine 1-phosphate receptor EDG-1 in vascular smooth muscle cell proliferation and migration
    • Kluk MJ, Hla T. Role of the sphingosine 1-phosphate receptor EDG-1 in vascular smooth muscle cell proliferation and migration. Circ. Research 2001; 89:496-502.
    • (2001) Circ. Research , vol.89 , pp. 496-502
    • Kluk, M.J.1    Hla, T.2
  • 61
    • 5644293131 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate stimulates smooth muscle cell differentiation and proliferation by activating separate serum response factor co-factors
    • Lockman K, Hinson JS, Medlin MD, Morris D, Taylor JM, Mack CP. Sphingosine 1-phosphate stimulates smooth muscle cell differentiation and proliferation by activating separate serum response factor co-factors. J Biol Chem 2004; 279:42422-30.
    • (2004) J Biol Chem , vol.279 , pp. 42422-42430
    • Lockman, K.1    Hinson, J.S.2    Medlin, M.D.3    Morris, D.4    Taylor, J.M.5    Mack, C.P.6
  • 62
    • 0033564744 scopus 로고    scopus 로고
    • Induction and suppression of endothelial cell apoptosis by sphingolipids: A possible in vitro model for cell-cell interactions between platelets and endothelial cells
    • Hisano N, Yatomi Y, Satoh K, Akimoto S, Mitsumata M, Fujino MA, et al. Induction and suppression of endothelial cell apoptosis by sphingolipids: A possible in vitro model for cell-cell interactions between platelets and endothelial cells. Blood 1999; 93:4293-9.
    • (1999) Blood , vol.93 , pp. 4293-4299
    • Hisano, N.1    Yatomi, Y.2    Satoh, K.3    Akimoto, S.4    Mitsumata, M.5    Fujino, M.A.6
  • 63
    • 4644269059 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate receptor regulation of N-cadherin mediates vascular stabilization
    • Paik JH, Skoura A, Chae SS, Cowan AE, Han DK, Proia RL, et al. Sphingosine 1-phosphate receptor regulation of N-cadherin mediates vascular stabilization. Genes Dev 2004; 18:2392-403.
    • (2004) Genes Dev , vol.18 , pp. 2392-2403
    • Paik, J.H.1    Skoura, A.2    Chae, S.S.3    Cowan, A.E.4    Han, D.K.5    Proia, R.L.6
  • 66
    • 42249092864 scopus 로고    scopus 로고
    • The lysophospholipid mediator sphingosine 1-phosphate promotes angiogenesis in vivo in ischemic hindlimbs of mice
    • Oyama O, Sugimoto N, Qi X, Takuwa N, Mizugishi K, Koizumi J, et al. The lysophospholipid mediator sphingosine 1-phosphate promotes angiogenesis in vivo in ischemic hindlimbs of mice. Cardiovas Res 2008; 78:301-7.
    • (2008) Cardiovas Res , vol.78 , pp. 301-307
    • Oyama, O.1    Sugimoto, N.2    Qi, X.3    Takuwa, N.4    Mizugishi, K.5    Koizumi, J.6
  • 67
    • 42249104208 scopus 로고    scopus 로고
    • Sustained release of sphingosine 1-phosphate for therapeutic arteriogenesis and bone tissue engineering
    • Sefcik LS, Petrie Aronin CE, Wieghaus KA, Botchwey EA. Sustained release of sphingosine 1-phosphate for therapeutic arteriogenesis and bone tissue engineering. Biomaterials 2008; 29:2869-77.
    • (2008) Biomaterials , vol.29 , pp. 2869-2877
    • Sefcik, L.S.1    Petrie Aronin, C.E.2    Wieghaus, K.A.3    Botchwey, E.A.4
  • 68
    • 3042588831 scopus 로고    scopus 로고
    • Molecular regulation of vascular smooth muscle cell differentiation in development and disease
    • Owens GK, Kumar MS, Wamhoff BR. Molecular regulation of vascular smooth muscle cell differentiation in development and disease. Physiol Rev 2004; 84:767-801.
    • (2004) Physiol Rev , vol.84 , pp. 767-801
    • Owens, G.K.1    Kumar, M.S.2    Wamhoff, B.R.3
  • 69
    • 0026418308 scopus 로고
    • Inhibition of neointimal smooth-muscle accumulation after angioplasty by an antibody to PDGF
    • Ferns GA, Raines EW, Sprugel KH, Motani AS, Reidy MA, Ross R. Inhibition of neointimal smooth-muscle accumulation after angioplasty by an antibody to PDGF. Science 1991; 253:1129-32.
    • (1991) Science , vol.253 , pp. 1129-1132
    • Ferns, G.A.1    Raines, E.W.2    Sprugel, K.H.3    Motani, A.S.4    Reidy, M.A.5    Ross, R.6
  • 70
    • 4644259224 scopus 로고    scopus 로고
    • Vascular sphingosine-1-phosphate S1P1 and S1P3 receptors
    • Waeber C, Blondeau N, Salomone S. Vascular sphingosine-1-phosphate S1P1 and S1P3 receptors. Drug News Perspect 2004; 17:365-82.
    • (2004) Drug News Perspect , vol.17 , pp. 365-382
    • Waeber, C.1    Blondeau, N.2    Salomone, S.3
  • 71
    • 1842455323 scopus 로고    scopus 로고
    • Point-Counterpoint of Sphingosine 1-Phosphate Metabolism
    • Saba JD and Hla T. Point-Counterpoint of Sphingosine 1-Phosphate Metabolism. Circ Res 2004; 94:724-34.
    • (2004) Circ Res , vol.94 , pp. 724-734
    • Saba, J.D.1    Hla, T.2
  • 72
    • 51749084528 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate receptor subtypes differentially regulate smooth muscle cell phenotype
    • Wamhoff BR, Lynch KR, Macdonald TL, Owens GK. Sphingosine 1-phosphate receptor subtypes differentially regulate smooth muscle cell phenotype. Arterioscler Thromb Vasc Biol 2008; 28:1454-61.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 1454-1461
    • Wamhoff, B.R.1    Lynch, K.R.2    Macdonald, T.L.3    Owens, G.K.4
  • 73
    • 34548834687 scopus 로고    scopus 로고
    • Regulation of arterial lesions in mice depends on differential smooth muscle cell migration: A role for sphingosine 1-phosphate receptors
    • Inoue S, Nakazawa T, Cho A, Dastvan F, Shilling D, Daum G, et al. Regulation of arterial lesions in mice depends on differential smooth muscle cell migration: a role for sphingosine 1-phosphate receptors. J Vasc Surg 2007; 46:756-63.
    • (2007) J Vasc Surg , vol.46 , pp. 756-763
    • Inoue, S.1    Nakazawa, T.2    Cho, A.3    Dastvan, F.4    Shilling, D.5    Daum, G.6
  • 74
    • 36148971252 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate receptor 2 negatively regulates neointimal formation in mouse arteries
    • Shimizu T, Nakazawa T, Cho A, Dastvan F, Shilling D, Daum G, et al. Sphingosine 1-phosphate receptor 2 negatively regulates neointimal formation in mouse arteries. Circ Res 2007; 101:995-1000.
    • (2007) Circ Res , vol.101 , pp. 995-1000
    • Shimizu, T.1    Nakazawa, T.2    Cho, A.3    Dastvan, F.4    Shilling, D.5    Daum, G.6
  • 75
    • 0031729124 scopus 로고    scopus 로고
    • Diversity of cellular receptors and functions for the lysophospholipid growth factors lysophosphatidic acid and sphingosine 1-phosphate
    • Goetzl EJ, An SZ. Diversity of cellular receptors and functions for the lysophospholipid growth factors lysophosphatidic acid and sphingosine 1-phosphate. FASEB J 1998; 12:1589-98.
    • (1998) FASEB J , vol.12 , pp. 1589-1598
    • Goetzl, E.J.1    An, S.Z.2
  • 76
    • 0034055480 scopus 로고    scopus 로고
    • Lysophosphatidic acid and sphingosine 1-phosphate stimualte endothelial cell woudn healing
    • Lee H, Goetzl EJ, An SZ. Lysophosphatidic acid and sphingosine 1-phosphate stimualte endothelial cell woudn healing. Am J Physiol Cell Physiol 2000; 278:612-8.
    • (2000) Am J Physiol Cell Physiol , vol.278 , pp. 612-618
    • Lee, H.1    Goetzl, E.J.2    An, S.Z.3
  • 77
    • 23044513514 scopus 로고    scopus 로고
    • Lysophospholipids enhance matrix metalloproteinase-2 expression in human endothelial cells
    • Wu WT, Chen CN, Lin CI, Chen JH, Lee H. Lysophospholipids enhance matrix metalloproteinase-2 expression in human endothelial cells. Endocrinology 2005; 146:3387-400.
    • (2005) Endocrinology , vol.146 , pp. 3387-3400
    • Wu, W.T.1    Chen, C.N.2    Lin, C.I.3    Chen, J.H.4    Lee, H.5
  • 78
    • 0033452587 scopus 로고    scopus 로고
    • Induction of endothelial cell chemotaxis by sphingosine 1-phosphate and stabilization of endothelial monolayer barrier function by lysophosphatidic acid, potential mediators of hematopoietic angiogenesis
    • English D, Kovala AT, Welch Z, Harvey KA, Siddiqui RA, Brindley DN, et al. Induction of endothelial cell chemotaxis by sphingosine 1-phosphate and stabilization of endothelial monolayer barrier function by lysophosphatidic acid, potential mediators of hematopoietic angiogenesis. J Hematother Stem Cell Res 1999; 8:627-34.
    • (1999) J Hematother Stem Cell Res , vol.8 , pp. 627-634
    • English, D.1    Kovala, A.T.2    Welch, Z.3    Harvey, K.A.4    Siddiqui, R.A.5    Brindley, D.N.6
  • 79
    • 0036786445 scopus 로고    scopus 로고
    • Characterization of lpa(2) (Edg4) and lpa(1)/lpa(2) (Edg2/Edg4) lysophosphatidic acid receptor knockout mice: Signaling deficits without obvious phenotypic abnormality attributable to lpa(2)
    • Contos JJ, Ishii I, Fukushima N, Kingsbury MA, Ye X, Kawamura S, et al. Characterization of lpa(2) (Edg4) and lpa(1)/lpa(2) (Edg2/Edg4) lysophosphatidic acid receptor knockout mice: signaling deficits without obvious phenotypic abnormality attributable to lpa(2). Mol Cell Biol 2002; 22:6921-9.
    • (2002) Mol Cell Biol , vol.22 , pp. 6921-6929
    • Contos, J.J.1    Ishii, I.2    Fukushima, N.3    Kingsbury, M.A.4    Ye, X.5    Kawamura, S.6
  • 80
  • 82
    • 33748757239 scopus 로고    scopus 로고
    • Autotaxin stabilizes blood vessels and is required for embryonic vasculature by producing lysophosphatidic acid
    • Tanaka M, Okudaira S, Kishi Y, Ohkawa R, Iseki S, Ota M, et al. Autotaxin stabilizes blood vessels and is required for embryonic vasculature by producing lysophosphatidic acid. J Biol Chem 2006; 281:25822-30.
    • (2006) J Biol Chem , vol.281 , pp. 25822-25830
    • Tanaka, M.1    Okudaira, S.2    Kishi, Y.3    Ohkawa, R.4    Iseki, S.5    Ota, M.6
  • 85
    • 0022553197 scopus 로고    scopus 로고
    • Stimulation of angiogenesis by adenosine on the chick chorioallantoic membrane
    • Dusseau JW, Hutchins PM, Malbasa DS. Stimulation of angiogenesis by adenosine on the chick chorioallantoic membrane. Circ Res 2986; 59:163-70.
    • Circ Res , vol.2986 , Issue.59 , pp. 163-170
    • Dusseau, J.W.1    Hutchins, P.M.2    Malbasa, D.S.3
  • 86
    • 23044510839 scopus 로고    scopus 로고
    • Growth regulation of the vascular system: An emerging role for adenosine
    • Adair TH. Growth regulation of the vascular system: an emerging role for adenosine. Am J Physiol Regul Integr Comp Physiol 2005; 289:283-96.
    • (2005) Am J Physiol Regul Integr Comp Physiol , vol.289 , pp. 283-296
    • Adair, T.H.1
  • 87
    • 0035574519 scopus 로고    scopus 로고
    • Roles of adenosine and nitric oxide in skeletal muscle in acute and chronic hypoxia
    • Marshall JM. Roles of adenosine and nitric oxide in skeletal muscle in acute and chronic hypoxia. Adv Exp Med Biol 2001; 502:349-63.
    • (2001) Adv Exp Med Biol , vol.502 , pp. 349-363
    • Marshall, J.M.1
  • 88
    • 1442278141 scopus 로고    scopus 로고
    • Adenosine receptors and wound healing
    • Cronstein BN. Adenosine receptors and wound healing. Scientific World Journal 2004; 4:1-8.
    • (2004) Scientific World Journal , vol.4 , pp. 1-8
    • Cronstein, B.N.1
  • 89
    • 85008983226 scopus 로고
    • The effect of long-term vasodilation on capillary growth and performance in rabbit heart and skeletal muscle
    • Ziada AM, Hudlicka O, Tyler KR, Wright AJ. The effect of long-term vasodilation on capillary growth and performance in rabbit heart and skeletal muscle. Cardiovasc Res 1984; 18:724-32.
    • (1984) Cardiovasc Res , vol.18 , pp. 724-732
    • Ziada, A.M.1    Hudlicka, O.2    Tyler, K.R.3    Wright, A.J.4
  • 90
    • 0037155773 scopus 로고    scopus 로고
    • Differential expression of adensonie receptors in human endoethelial cells: Role of A(2B) receptors in angiogenic factor regulation
    • Feoktistov I, Goldstein AE, Ryzhov S, Zeng D, Belardinelli L, Boyno-Yasenetckaya T, et al. Differential expression of adensonie receptors in human endoethelial cells: role of A(2B) receptors in angiogenic factor regulation. Circ Res 2002; 90:531-8.
    • (2002) Circ Res , vol.90 , pp. 531-538
    • Feoktistov, I.1    Goldstein, A.E.2    Ryzhov, S.3    Zeng, D.4    Belardinelli, L.5    Boyno-Yasenetckaya, T.6
  • 91
    • 0041343279 scopus 로고    scopus 로고
    • Pinhal-Enfield G, Ramanathan M, Hasko G, Vogel SN, Salzman AL, Boons GJ, et al. An angiogenic switch in macrophages involving synergy between toll-like receptors 2, 4, 7 and 9 and adenosine A(2A) receptors. Am J Pathol 2003; 163:711-21.
    • Pinhal-Enfield G, Ramanathan M, Hasko G, Vogel SN, Salzman AL, Boons GJ, et al. An angiogenic switch in macrophages involving synergy between toll-like receptors 2, 4, 7 and 9 and adenosine A(2A) receptors. Am J Pathol 2003; 163:711-21.
  • 92
    • 36348967128 scopus 로고    scopus 로고
    • A(1) adenosine receptor activation promotes angiogenesis and release of VEGF from monocytes
    • Clark AN, Youkey R, Liu XP, Jia LG, Blatt R, Day YJ, et al. A(1) adenosine receptor activation promotes angiogenesis and release of VEGF from monocytes. Circ Res 2007; 101:1130-8.
    • (2007) Circ Res , vol.101 , pp. 1130-1138
    • Clark, A.N.1    Youkey, R.2    Liu, X.P.3    Jia, L.G.4    Blatt, R.5    Day, Y.J.6
  • 93
    • 0035209620 scopus 로고    scopus 로고
    • International Union of Pharmacology XXV. Nomenclature and classification of adenosine receptors
    • Fredholm BB, Ijzerman AP, Jacobson KA, Klotz KN, Linden J. International Union of Pharmacology XXV. Nomenclature and classification of adenosine receptors. Pharma Rev 2001; 53:527-52.
    • (2001) Pharma Rev , vol.53 , pp. 527-552
    • Fredholm, B.B.1    Ijzerman, A.P.2    Jacobson, K.A.3    Klotz, K.N.4    Linden, J.5
  • 95
    • 0042844744 scopus 로고    scopus 로고
    • Natural products as sources of new drugs over the period 1981-2002
    • Newman DJ, Cragg GM, Snader KM. Natural products as sources of new drugs over the period 1981-2002. J Nat Prod 2003; 66:1022-37.
    • (2003) J Nat Prod , vol.66 , pp. 1022-1037
    • Newman, D.J.1    Cragg, G.M.2    Snader, K.M.3
  • 97
    • 0034082239 scopus 로고    scopus 로고
    • The influence of natural products upon drug discovery
    • Newman DJ, Cragg GM, Snader KM. The influence of natural products upon drug discovery. Nat Prod Rep 2000; 17:215-34.
    • (2000) Nat Prod Rep , vol.17 , pp. 215-234
    • Newman, D.J.1    Cragg, G.M.2    Snader, K.M.3
  • 100
    • 33644932823 scopus 로고    scopus 로고
    • Total synthesis and evaluation of [psi[CH2NH]Tpg(4)]vancomycin aglycon: Reengineering vancomycin for dual D-Ala-D-Ala and D-Ala-D-Lac binding
    • Crowley BM, Boger DL. Total synthesis and evaluation of [psi[CH2NH]Tpg(4)]vancomycin aglycon: Reengineering vancomycin for dual D-Ala-D-Ala and D-Ala-D-Lac binding. J Am Chem Soc 2006; 128:2885-92.
    • (2006) J Am Chem Soc , vol.128 , pp. 2885-2892
    • Crowley, B.M.1    Boger, D.L.2
  • 101
    • 1542376217 scopus 로고    scopus 로고
    • Angiogenesis and antiangiogenesis activity of Chinese medicinal herbal extracts
    • Wang S, Zheng Z, Weng Y, Yu Y, Zhang D, Fan W, Dai R, Hu Z. Angiogenesis and antiangiogenesis activity of Chinese medicinal herbal extracts. Life Sci 2004; 74:2467-78.
    • (2004) Life Sci , vol.74 , pp. 2467-2478
    • Wang, S.1    Zheng, Z.2    Weng, Y.3    Yu, Y.4    Zhang, D.5    Fan, W.6    Dai, R.7    Hu, Z.8
  • 102
    • 0026651085 scopus 로고    scopus 로고
    • Renaud S, de Lorgeril M. Wine, alcohol, platelets, and the French paradox for coronary heart disease. Lancet 1992; 339:1523-6.
    • Renaud S, de Lorgeril M. Wine, alcohol, platelets, and the French paradox for coronary heart disease. Lancet 1992; 339:1523-6.
  • 103
    • 0033614719 scopus 로고    scopus 로고
    • Why heart disease mortality is low in France: The time lag explanation
    • Law M, Wald N. Why heart disease mortality is low in France: The time lag explanation. BMJ 1999; 318:1471-6.
    • (1999) BMJ , vol.318 , pp. 1471-1476
    • Law, M.1    Wald, N.2
  • 104
    • 33644659068 scopus 로고    scopus 로고
    • Resveratrol in cardioprotection: A therapeutic promise of alternative medicine
    • Das DK, Maulik N. Resveratrol in cardioprotection: a therapeutic promise of alternative medicine. Mol Interv 2006; 6:36-47.
    • (2006) Mol Interv , vol.6 , pp. 36-47
    • Das, D.K.1    Maulik, N.2
  • 105
    • 34548696625 scopus 로고    scopus 로고
    • Effects of resveratrol on number and activity of endothelial progenitor cells from human peripheral blood
    • Wang XB, Huang J, Zou JG, Su EB, Shan QJ, Yang ZJ, Cao KJ. Effects of resveratrol on number and activity of endothelial progenitor cells from human peripheral blood. Clin Exp Pharmacol Physiol 2007; 34:1109-15.
    • (2007) Clin Exp Pharmacol Physiol , vol.34 , pp. 1109-1115
    • Wang, X.B.1    Huang, J.2    Zou, J.G.3    Su, E.B.4    Shan, Q.J.5    Yang, Z.J.6    Cao, K.J.7
  • 106
    • 30744441162 scopus 로고    scopus 로고
    • Resveratrol ameliorates myocardial damage by inducing vascular endothelial growth factor-angiogenesis and tyrosine kinase receptor Flk-1
    • Fukuda S, Kaga S, Zhan L, Bagchi D, Das DK, Bertelli A, et al. Resveratrol ameliorates myocardial damage by inducing vascular endothelial growth factor-angiogenesis and tyrosine kinase receptor Flk-1. Cell Biochem Biophys 2006; 44:43-9.
    • (2006) Cell Biochem Biophys , vol.44 , pp. 43-49
    • Fukuda, S.1    Kaga, S.2    Zhan, L.3    Bagchi, D.4    Das, D.K.5    Bertelli, A.6
  • 107
    • 0037167677 scopus 로고    scopus 로고
    • Resveratrol, a polyphenolic phytoalexin present in red wine, enhances expression and activity of endothelial nitric oxide synthase
    • Wallerath T, Deckert G, Ternes T, Anderson H, Huige L, Witte K, et al. Resveratrol, a polyphenolic phytoalexin present in red wine, enhances expression and activity of endothelial nitric oxide synthase. Circ 2002; 106:1652-8.
    • (2002) Circ , vol.106 , pp. 1652-1658
    • Wallerath, T.1    Deckert, G.2    Ternes, T.3    Anderson, H.4    Huige, L.5    Witte, K.6
  • 112
    • 2442521050 scopus 로고    scopus 로고
    • Anticarcinogenic effect of Panax ginseng C.A. Meyer and identification of active compounds
    • Yun T, Lee Y, Lee YH, Kim SI, Yun HY. Anticarcinogenic effect of Panax ginseng C.A. Meyer and identification of active compounds. J Korean Med Sci 2001; 16: 6-18.
    • (2001) J Korean Med Sci , vol.16 , pp. 6-18
    • Yun, T.1    Lee, Y.2    Lee, Y.H.3    Kim, S.I.4    Yun, H.Y.5
  • 113
    • 0033461806 scopus 로고    scopus 로고
    • American ginseng and breast cancer therapeutic agents synergistically inhibit MCF-7 breast cancer cell growth
    • Duda RB, Zhong Y, Navas V, Li MZ, Toy BR, Alavarez JG. American ginseng and breast cancer therapeutic agents synergistically inhibit MCF-7 breast cancer cell growth. J Surg Oncol 1999; 72:230-9.
    • (1999) J Surg Oncol , vol.72 , pp. 230-239
    • Duda, R.B.1    Zhong, Y.2    Navas, V.3    Li, M.Z.4    Toy, B.R.5    Alavarez, J.G.6
  • 114
    • 33646556664 scopus 로고    scopus 로고
    • Signaling pathway of ginsenoside-Rg1 leading to nitric oxide production in endothelial cells
    • Leung KW, Cheng YK, Mak NK, Chan KKC, Fan TPD, Wong RNS. Signaling pathway of ginsenoside-Rg1 leading to nitric oxide production in endothelial cells. FEBS Letters 2006; 580:3211-6.
    • (2006) FEBS Letters , vol.580 , pp. 3211-3216
    • Leung, K.W.1    Cheng, Y.K.2    Mak, N.K.3    Chan, K.K.C.4    Fan, T.P.D.5    Wong, R.N.S.6
  • 115
    • 28744458919 scopus 로고    scopus 로고
    • Elucidation of the mechanisms underlying the angiogenic effects of ginsenoside Rg1 in vivo and in vitro
    • Yue P, Wong D, Ha WY, Fung MC, Mak NK, Yeung HW, et al. Elucidation of the mechanisms underlying the angiogenic effects of ginsenoside Rg1 in vivo and in vitro. Angiogenesis 2005; 8:205-16.
    • (2005) Angiogenesis , vol.8 , pp. 205-216
    • Yue, P.1    Wong, D.2    Ha, W.Y.3    Fung, M.C.4    Mak, N.K.5    Yeung, H.W.6
  • 116
    • 0028914837 scopus 로고
    • Ginsenosides of the protopanaxatriol group cause endothelium-dependent relaxation in the rat aorta
    • Kang SY, Schini-Kerth VB, Kim ND. Ginsenosides of the protopanaxatriol group cause endothelium-dependent relaxation in the rat aorta. Life Sciences 1995; 56:1577-86.
    • (1995) Life Sciences , vol.56 , pp. 1577-1586
    • Kang, S.Y.1    Schini-Kerth, V.B.2    Kim, N.D.3
  • 117
    • 18044385758 scopus 로고    scopus 로고
    • A natural compound (ginsenoside Re) isolated from Panax ginseng as a novel angiogenic agent for tissue regeneration
    • Huang YC, Chen CT, Chen SC, Lai PH, Liang HC, Chang Y, et al. A natural compound (ginsenoside Re) isolated from Panax ginseng as a novel angiogenic agent for tissue regeneration. Pharma Res 2005; 22:636-46.
    • (2005) Pharma Res , vol.22 , pp. 636-646
    • Huang, Y.C.1    Chen, C.T.2    Chen, S.C.3    Lai, P.H.4    Liang, H.C.5    Chang, Y.6
  • 118
    • 0037195522 scopus 로고    scopus 로고
    • Glucocorticoids inhibit vascular endothelial growth factor expression in growth plate chondrocytes
    • Koedam Koedam JA, Smink JJ, van Buul-Offers SC. Glucocorticoids inhibit vascular endothelial growth factor expression in growth plate chondrocytes. Mol Cell Endocrinol 2002; 197:35-44.
    • (2002) Mol Cell Endocrinol , vol.197 , pp. 35-44
    • Koedam Koedam, J.A.1    Smink, J.J.2    van Buul-Offers, S.C.3
  • 119
    • 33748489728 scopus 로고    scopus 로고
    • Therapeutic application of longcirculating liposomal gluocorticoids in auto-immune diseases and cancer
    • Schiffelers RM, Banciu M, Metselaar JM, Storm G. Therapeutic application of longcirculating liposomal gluocorticoids in auto-immune diseases and cancer. J Liposome Res 2006; 16:185-94.
    • (2006) J Liposome Res , vol.16 , pp. 185-194
    • Schiffelers, R.M.1    Banciu, M.2    Metselaar, J.M.3    Storm, G.4
  • 120
    • 0030838299 scopus 로고    scopus 로고
    • Ginsenoside-Rg1, one of the major active molecules from Panax ginseng, is a functional ligand of glucocorticoid receptor
    • Lee YJ, Chung E, Lee KY, Lee YH, Huh B, Lee SK. Ginsenoside-Rg1, one of the major active molecules from Panax ginseng, is a functional ligand of glucocorticoid receptor. Mol Cell Endocrinol 1997; 133:135-40.
    • (1997) Mol Cell Endocrinol , vol.133 , pp. 135-140
    • Lee, Y.J.1    Chung, E.2    Lee, K.Y.3    Lee, Y.H.4    Huh, B.5    Lee, S.K.6
  • 122
    • 0015785965 scopus 로고
    • Pharmacology of dieruloyl methane (curcumin), a non-steroidal anti-inflammatory agent
    • Srimal RC, Dhawan BN. Pharmacology of dieruloyl methane (curcumin), a non-steroidal anti-inflammatory agent. J Pharm Pharmacol 1973; 25:447-52.
    • (1973) J Pharm Pharmacol , vol.25 , pp. 447-452
    • Srimal, R.C.1    Dhawan, B.N.2
  • 123
    • 0022972545 scopus 로고
    • Evaluation of anti-inflammatory property of curcumin (diferuloyl methane) in patients with postoperative inflammation
    • Satoskar RR, Shah SJ, Shenoy SG. Evaluation of anti-inflammatory property of curcumin (diferuloyl methane) in patients with postoperative inflammation. Int J Clin Pharma Ther Tox 1986; 24:651-4.
    • (1986) Int J Clin Pharma Ther Tox , vol.24 , pp. 651-654
    • Satoskar, R.R.1    Shah, S.J.2    Shenoy, S.G.3
  • 124
  • 125
    • 0017075410 scopus 로고
    • Antioxidant activity of curcumin and related compounds
    • Sharma OP. Antioxidant activity of curcumin and related compounds. Biochem Pharma 1976; 25:1811-2.
    • (1976) Biochem Pharma , vol.25 , pp. 1811-1812
    • Sharma, O.P.1
  • 126
    • 0021815329 scopus 로고
    • Natural antioxidants III. Antioxidative components isolated from rhizome of Curcuma longa L
    • Toda S, Miyase T, Arichi H, Tanizawa H, Takino Y. Natural antioxidants III. Antioxidative components isolated from rhizome of Curcuma longa L. Chem Pharma Bulletin 1985; 33:1725-8.
    • (1985) Chem Pharma Bulletin , vol.33 , pp. 1725-1728
    • Toda, S.1    Miyase, T.2    Arichi, H.3    Tanizawa, H.4    Takino, Y.5
  • 128
    • 0032886483 scopus 로고    scopus 로고
    • Functional roles of PECAM-1 (CD31) and VE Cadherin (CD144) in tube assembly and lumen formation in three dimensional collagen rats
    • Yang S, Graham J, Kahn JW, Schwartz EA, Gerritsen ME. Functional roles of PECAM-1 (CD31) and VE Cadherin (CD144) in tube assembly and lumen formation in three dimensional collagen rats. Am J Pathol 1999; 155:887-95.
    • (1999) Am J Pathol , vol.155 , pp. 887-895
    • Yang, S.1    Graham, J.2    Kahn, J.W.3    Schwartz, E.A.4    Gerritsen, M.E.5
  • 131
    • 0018222291 scopus 로고
    • The metabolism and excretion of curcumin (1,7-bis-(4-hydroxy-3methosyphenyl)-1,6-hepadine-3,5-dione) in the rat
    • Holder GM, Plummer JL, Ryan AJ. The metabolism and excretion of curcumin (1,7-bis-(4-hydroxy-3methosyphenyl)-1,6-hepadine-3,5-dione) in the rat. Xenobiotica 1978; 8:761-76.
    • (1978) Xenobiotica , vol.8 , pp. 761-776
    • Holder, G.M.1    Plummer, J.L.2    Ryan, A.J.3
  • 132
    • 0032744537 scopus 로고    scopus 로고
    • Curcumin enhances wound healing in streptozotocin induced diabetic rats and genetically diabetic mice
    • Sidhu GS, Mani H, Gaddipati JP, Singh AK, Seth P, Banaudha KK, et al. Curcumin enhances wound healing in streptozotocin induced diabetic rats and genetically diabetic mice. Wound Repair Regen 1999; 7:362-74.
    • (1999) Wound Repair Regen , vol.7 , pp. 362-374
    • Sidhu, G.S.1    Mani, H.2    Gaddipati, J.P.3    Singh, A.K.4    Seth, P.5    Banaudha, K.K.6
  • 134
    • 2542450825 scopus 로고    scopus 로고
    • Role of curcumin, a naturally occurring phenolic compound of turmeric in accelerating the repair of excision wound, in mice whole-body exposed to various doses of γ-radiation
    • Jagetia GC, Rajanikant GK. Role of curcumin, a naturally occurring phenolic compound of turmeric in accelerating the repair of excision wound, in mice whole-body exposed to various doses of γ-radiation. J Surg Res 2004; 120:127-38.
    • (2004) J Surg Res , vol.120 , pp. 127-138
    • Jagetia, G.C.1    Rajanikant, G.K.2
  • 139
    • 0347320710 scopus 로고    scopus 로고
    • Thalidomide analogues demonstrate dual inhibition of both angiogenesis and prostate cancer
    • Capitosti SM, Hansen TP, Brown ML. Thalidomide analogues demonstrate dual inhibition of both angiogenesis and prostate cancer. Bioorg Med Chem 2004; 12:327-36.
    • (2004) Bioorg Med Chem , vol.12 , pp. 327-336
    • Capitosti, S.M.1    Hansen, T.P.2    Brown, M.L.3
  • 140
    • 0033635054 scopus 로고    scopus 로고
    • Protein instability in poly(lactic-co-glycolic acid) microparticles
    • van de Weert M, Hennink WE, Jiskoot W. Protein instability in poly(lactic-co-glycolic acid) microparticles. Pharm Res 2000; 17:1159-67.
    • (2000) Pharm Res , vol.17 , pp. 1159-1167
    • van de Weert, M.1    Hennink, W.E.2    Jiskoot, W.3
  • 141
    • 0033987939 scopus 로고    scopus 로고
    • Protein stability in controlled-release systems
    • Fu K, Klibanov AM, Langer R. Protein stability in controlled-release systems. Nat Biotechnol 2000; 18:24-5.
    • (2000) Nat Biotechnol , vol.18 , pp. 24-25
    • Fu, K.1    Klibanov, A.M.2    Langer, R.3
  • 144
    • 35348903141 scopus 로고    scopus 로고
    • Mechanistic interrogation of phthalimide neovascular factor 1 (PNF1) using network analysis tools
    • Wieghaus KA, Gianchandani EP, Papin JA, Brown ML, Botchwey EA. Mechanistic interrogation of phthalimide neovascular factor 1 (PNF1) using network analysis tools. Tissue Eng 2007; 13:2561-175.
    • (2007) Tissue Eng , vol.13 , pp. 2561-3175
    • Wieghaus, K.A.1    Gianchandani, E.P.2    Papin, J.A.3    Brown, M.L.4    Botchwey, E.A.5
  • 145
    • 53149085754 scopus 로고    scopus 로고
    • Novel pathway compendium analysis eludicates mechanism of pro-angiogenic synthetic small molecule with in vivo validation
    • Wieghaus KA, Gianchandani EP, Paige MA, Brown ML, Papin JA, Botchwey EA. Novel pathway compendium analysis eludicates mechanism of pro-angiogenic synthetic small molecule with in vivo validation. Bioinformatics 2008; 24:2384-90.
    • (2008) Bioinformatics , vol.24 , pp. 2384-2390
    • Wieghaus, K.A.1    Gianchandani, E.P.2    Paige, M.A.3    Brown, M.L.4    Papin, J.A.5    Botchwey, E.A.6
  • 147
    • 0344443651 scopus 로고    scopus 로고
    • Phosphorylation and action of the immunomodulator FTY720 inhibits vascular endothelial cell growth factor-induced vascular permeability
    • Sanchez T, Estrada-Hernandez T, Paik JH, et al. Phosphorylation and action of the immunomodulator FTY720 inhibits vascular endothelial cell growth factor-induced vascular permeability. J Biol Chem 2003; 278:47281-90.
    • (2003) J Biol Chem , vol.278 , pp. 47281-47290
    • Sanchez, T.1    Estrada-Hernandez, T.2    Paik, J.H.3
  • 148
    • 1842610148 scopus 로고    scopus 로고
    • Functional characterization of sphingosine 1-phosphate receptor agonist in human endothelial cells
    • Butler J, Lana D, Round O, LaMontagne K. Functional characterization of sphingosine 1-phosphate receptor agonist in human endothelial cells. Prostaglandins Other Lipid Med 2004; 73:29-45.
    • (2004) Prostaglandins Other Lipid Med , vol.73 , pp. 29-45
    • Butler, J.1    Lana, D.2    Round, O.3    LaMontagne, K.4
  • 149
    • 34147095398 scopus 로고    scopus 로고
    • The immunosuppressant FTY720 inhibits tumor angiogenesis via the sphingosine 1-phosphate receptor 1
    • Schmid G, Guba M, Ischenko I, Papyan A, Joka M, Schrepfer S, et al. The immunosuppressant FTY720 inhibits tumor angiogenesis via the sphingosine 1-phosphate receptor 1. J Cell Biochem 2007; 101:259-70.
    • (2007) J Cell Biochem , vol.101 , pp. 259-270
    • Schmid, G.1    Guba, M.2    Ischenko, I.3    Papyan, A.4    Joka, M.5    Schrepfer, S.6
  • 151
    • 0036434445 scopus 로고    scopus 로고
    • Enhancement of sphingosine 1-phosphate-induced migration of vascular endothelial cells and smooth muscle cells by an EDG-5 antagonist
    • Osada M, Yatomi Y, Ohmori T, Ikeda H, Ozaki Y. Enhancement of sphingosine 1-phosphate-induced migration of vascular endothelial cells and smooth muscle cells by an EDG-5 antagonist. Biochem Biophys Res Commun 2002; 299:483-7.
    • (2002) Biochem Biophys Res Commun , vol.299 , pp. 483-487
    • Osada, M.1    Yatomi, Y.2    Ohmori, T.3    Ikeda, H.4    Ozaki, Y.5
  • 153
    • 42349117330 scopus 로고    scopus 로고
    • Activation of sphingosine kinase-1 mediates induction of endothelial cell proliferation and angiogenesis by epoxyeicosatrienoic acids
    • Yan G, Chen S, You B, Sun J. Activation of sphingosine kinase-1 mediates induction of endothelial cell proliferation and angiogenesis by epoxyeicosatrienoic acids. Cardiovasc Res 2008; 78:308-14.
    • (2008) Cardiovasc Res , vol.78 , pp. 308-314
    • Yan, G.1    Chen, S.2    You, B.3    Sun, J.4
  • 155
    • 37849001331 scopus 로고    scopus 로고
    • Analysis of sphingosine 1-phosphate receptors involved in constriction of isolated cerebral arteries with receptor null mice and pharmacological tools
    • Salomone S, Potts EM, Tyndall S, Ip PC, Chun J, Brinkmann V, Waeber C. Analysis of sphingosine 1-phosphate receptors involved in constriction of isolated cerebral arteries with receptor null mice and pharmacological tools. Br J Pharmacol 2008; 153:140-7.
    • (2008) Br J Pharmacol , vol.153 , pp. 140-147
    • Salomone, S.1    Potts, E.M.2    Tyndall, S.3    Ip, P.C.4    Chun, J.5    Brinkmann, V.6    Waeber, C.7
  • 157
    • 33646536386 scopus 로고    scopus 로고
    • Phosphorothioate analogues of alkyl lysophosphatidic acid as LPA3 receptor-selective agonists
    • Qian L, Xu Y, Simper T, Jiang G, Aoki J, Umezu-Goto M, et al. Phosphorothioate analogues of alkyl lysophosphatidic acid as LPA3 receptor-selective agonists. Chem Med Chem 2006; 1:376-83.
    • (2006) Chem Med Chem , vol.1 , pp. 376-383
    • Qian, L.1    Xu, Y.2    Simper, T.3    Jiang, G.4    Aoki, J.5    Umezu-Goto, M.6
  • 158
    • 41849107561 scopus 로고    scopus 로고
    • Specific LPA receptor subtype mediation of LPA-induced hypertrophy of cardiac myocytes and involvement of Akt and NFkappaB signal pathways
    • Chen J, Chen Y, Zhu W, Han Y, Han B, Xu R, et al. Specific LPA receptor subtype mediation of LPA-induced hypertrophy of cardiac myocytes and involvement of Akt and NFkappaB signal pathways. J Cell Biochem 2008; 103:1718-31.
    • (2008) J Cell Biochem , vol.103 , pp. 1718-1731
    • Chen, J.1    Chen, Y.2    Zhu, W.3    Han, Y.4    Han, B.5    Xu, R.6
  • 159
    • 0035206909 scopus 로고    scopus 로고
    • Activity of 2-substituted lysophosphatidic acid (LPA) analogs at LPA receptors: Discovery of a LPA1/LPA3 receptor antagonist
    • Heise CE, Santos WL, Schreihofer AM, Heasley BH, Mukhin YV, Macdonald TL, Lynch KR. Activity of 2-substituted lysophosphatidic acid (LPA) analogs at LPA receptors: discovery of a LPA1/LPA3 receptor antagonist. Mol Pharmacol 2001; 60:1173-80.
    • (2001) Mol Pharmacol , vol.60 , pp. 1173-1180
    • Heise, C.E.1    Santos, W.L.2    Schreihofer, A.M.3    Heasley, B.H.4    Mukhin, Y.V.5    Macdonald, T.L.6    Lynch, K.R.7
  • 160
    • 44149117249 scopus 로고    scopus 로고
    • Mechanisms of the lysophosphatidic acid-induced increase in [Ca(2+)](i) in skeletal muscle cells
    • Xu YJ, Tappia PS, Goyal RK, Dhalla NS. Mechanisms of the lysophosphatidic acid-induced increase in [Ca(2+)](i) in skeletal muscle cells. J Cell Mol Med 2008; 12:942-54.
    • (2008) J Cell Mol Med , vol.12 , pp. 942-954
    • Xu, Y.J.1    Tappia, P.S.2    Goyal, R.K.3    Dhalla, N.S.4
  • 161
    • 43049148411 scopus 로고    scopus 로고
    • Cancer-derived lysophosphatidic acid stimulates differentiation of human mesenchymal stem cells to myofibroblast-like cells
    • Jeon ES, Moon HJ, Lee MJ, Song HY, Kim YM, Cho M, et al. Cancer-derived lysophosphatidic acid stimulates differentiation of human mesenchymal stem cells to myofibroblast-like cells. Stem Cells 2008; 26:789-97.
    • (2008) Stem Cells , vol.26 , pp. 789-797
    • Jeon, E.S.1    Moon, H.J.2    Lee, M.J.3    Song, H.Y.4    Kim, Y.M.5    Cho, M.6
  • 162
    • 57049111034 scopus 로고    scopus 로고
    • Lysosphosphatidic acid (LPA) modulates monocyte migration directly and via LPA-stimulated endothelial cells
    • Epub ahead of print
    • Gustin C, Van Steenbrugge M, Raes M. Lysosphosphatidic acid (LPA) modulates monocyte migration directly and via LPA-stimulated endothelial cells. Am J Physiol Cell Physiol 2008; [Epub ahead of print].
    • (2008) Am J Physiol Cell Physiol
    • Gustin, C.1    Van Steenbrugge, M.2    Raes, M.3
  • 163
    • 22144480136 scopus 로고    scopus 로고
    • LPA and S1P increase corneal epithelial and endothelial cell transcellular resistance
    • Yin F, Watsky MA. LPA and S1P increase corneal epithelial and endothelial cell transcellular resistance. Invest Ophthalmol Vis Sci 2005; 46:1927-33.
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , pp. 1927-1933
    • Yin, F.1    Watsky, M.A.2


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