Cobalt promotes angiogenesis via hypoxia-inducible factor and protects tubulointerstitium in the remnant kidney model

Laboratory Investigation

Volumn 85, Issue 10, 2005, Pages 1292-1307

  Tanaka, Tetsuhiro ^a   Kojima, Ichiro ^a   Ohse, Takamoto ^a   Ingelfinger, Julie R ^b   Adler, Stephen ^c   Fujita, Toshiro ^a   Nangaku, Masaomi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

Angiogenesis; Apoptosis; Cobalt; HIF 2; Hypoxia inducible factor (HIF) 1

Indexed keywords

COBALT CHLORIDE; HYPOXIA INDUCIBLE FACTOR 1; VIMENTIN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL PERMEABILITY; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; ENDOTHELIUM CELL; FEMALE; HYPOXIA; KIDNEY DISEASE; KIDNEY INJURY; KIDNEY TUBULE CELL; NICK END LABELING; NONHUMAN; PARTIAL NEPHRECTOMY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; RAT; REFRACTION INDEX; RENAL PROTECTION; SCORING SYSTEM; STATISTICAL SIGNIFICANCE;

ANIMALS; ANOXIA; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CAPILLARIES; CAPILLARY PERMEABILITY; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; COBALT; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; EPITHELIAL CELLS; FEMALE; HYPOXIA-INDUCIBLE FACTOR 1; IN SITU NICK-END LABELING; KIDNEY; KIDNEY DISEASES; KIDNEY GLOMERULUS; KIDNEY TUBULES; NEOVASCULARIZATION, PHYSIOLOGIC; NEPHRECTOMY; RATS; RATS, WISTAR; VIMENTIN;

EID: 25144475141     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: 10.1038/labinvest.3700328     Document Type: Article

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