A novel iron chelator that does not induce HIF-1 activity

Free Radical Biology and Medicine

Volumn 33, Issue 3, 2002, Pages 356-363

  Creighton Gutteridge, Mark ^a   Tyrrell, Rex M ^a  

^a University of Bath   (United Kingdom)

Author keywords

DFO; Free radicals; GAPDH; Gene expression; HIF 1; Hypoxia; Iron; Iron chelator; Oxidative stress

Indexed keywords

DEFEROXAMINE; HYPOXIA INDUCIBLE FACTOR 1; IRON CHELATING AGENT; MESSENGER RNA; N (2 HYDROXYBENZYL)SERINE; SALICYLALDEHYDE ISONICOTINOYLHYDRAZONE; UNCLASSIFIED DRUG; ALDEHYDE; DNA BINDING PROTEIN; DRUG DERIVATIVE; HIF1A PROTEIN, HUMAN; HYDRAZONE DERIVATIVE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; IRON; N-(2-HYDROXYBENZYL)SERINE; NUCLEAR PROTEIN; PHENOL DERIVATIVE; SALICYLALDEHYDE ISONICOTINOYL HYDRAZONE; SERINE; TRANSCRIPTION FACTOR;

ARTICLE; BINDING AFFINITY; CELL FUNCTION; CELL GROWTH; CONTROLLED STUDY; HOMEOSTASIS; HUMAN; HUMAN CELL; HYPOXIA; IRON CHELATION; IRON KINETICS; MOLECULAR WEIGHT; OXIDATIVE STRESS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN INDUCTION; SKIN CELL; TISSUE INJURY; ULTRAVIOLET A RADIATION; CELL HYPOXIA; CYTOLOGY; DRUG EFFECT; FIBROBLAST; GENETICS; METABOLISM; MUTATION; SKIN;

ALDEHYDES; CELL HYPOXIA; DEFEROXAMINE; DNA-BINDING PROTEINS; FIBROBLASTS; HUMAN; HYDRAZONES; IRON; IRON CHELATING AGENTS; MUTATION; NUCLEAR PROTEINS; PHENOLS; RNA, MESSENGER; SERINE; SKIN; SUPPORT, NON-U.S. GOV'T; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; TRANSCRIPTION FACTORS;

EID: 0036667557     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(02)00884-5     Document Type: Article

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