메뉴 건너뛰기




Volumn 12, Issue 2, 2006, Pages 65-75

Emerging medicinal roles for lysophospholipid signaling

Author keywords

[No Author keywords available]

Indexed keywords

1 (2 ETHYLPHENOXY) 3 (1,2,3,4 TETRAHYDRO 1 NAPHTHYLAMINO) 2 PROPANOL OXALATE; ANTINEOPLASTIC AGENT; CYCLOSPORIN; FINGOLIMOD; G PROTEIN COUPLED RECEPTOR; IMMUNOSUPPRESSIVE AGENT; KI 16425; LIPOPROTEIN A; LYSOPHOSPHOLIPID; NEUROTRANSMITTER; UNCLASSIFIED DRUG;

EID: 32044448106     PISSN: 14714914     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molmed.2005.12.001     Document Type: Review
Times cited : (227)

References (120)
  • 1
    • 0037082324 scopus 로고    scopus 로고
    • Target validation of G-protein coupled receptors
    • A. Wise Target validation of G-protein coupled receptors Drug Discov. Today 7 2002 235 246
    • (2002) Drug Discov. Today , vol.7 , pp. 235-246
    • Wise, A.1
  • 2
    • 2142851264 scopus 로고    scopus 로고
    • Lysophospholipid receptors: Signaling and biology
    • I. Ishii Lysophospholipid receptors: signaling and biology Annu. Rev. Biochem. 73 2004 321 354
    • (2004) Annu. Rev. Biochem. , vol.73 , pp. 321-354
    • Ishii, I.1
  • 3
    • 2442658976 scopus 로고    scopus 로고
    • Lysophospholipid G protein-coupled receptors
    • B. Anliker, and J. Chun Lysophospholipid G protein-coupled receptors J. Biol. Chem. 279 2004 20555 20558
    • (2004) J. Biol. Chem. , vol.279 , pp. 20555-20558
    • Anliker, B.1    Chun, J.2
  • 4
    • 0038004740 scopus 로고    scopus 로고
    • Targeting JNK for therapeutic benefit: From junk to gold?
    • A.M. Manning, and R.J. Davis Targeting JNK for therapeutic benefit: from junk to gold? Nat. Rev. Drug Discov. 2 2003 554 565
    • (2003) Nat. Rev. Drug Discov. , vol.2 , pp. 554-565
    • Manning, A.M.1    Davis, R.J.2
  • 6
    • 18944372230 scopus 로고    scopus 로고
    • Rho kinase, a promising drug target for neurological disorders
    • B.K. Mueller Rho kinase, a promising drug target for neurological disorders Nat. Rev. Drug Discov. 4 2005 387 398
    • (2005) Nat. Rev. Drug Discov. , vol.4 , pp. 387-398
    • Mueller, B.K.1
  • 7
    • 0036356038 scopus 로고    scopus 로고
    • Sphingosine kinases: A novel family of lipid kinases
    • H. Liu Sphingosine kinases: a novel family of lipid kinases Prog. Nucleic Acid Res. Mol. Biol. 71 2002 493 511
    • (2002) Prog. Nucleic Acid Res. Mol. Biol. , vol.71 , pp. 493-511
    • Liu, H.1
  • 8
    • 20944443148 scopus 로고    scopus 로고
    • Organ transplantation - How much of the promise has been realized?
    • R.I. Lechler Organ transplantation - how much of the promise has been realized? Nat. Med. 11 2005 605 613
    • (2005) Nat. Med. , vol.11 , pp. 605-613
    • Lechler, R.I.1
  • 9
    • 0028372227 scopus 로고
    • Fungal metabolites. Part 11. a potent immunosuppressive activity found in Isaria sinclairii metabolite
    • T. Fujita Fungal metabolites. Part 11. A potent immunosuppressive activity found in Isaria sinclairii metabolite J. Antibiot. (Tokyo) 47 1994 208 215
    • (1994) J. Antibiot. (Tokyo) , vol.47 , pp. 208-215
    • Fujita, T.1
  • 10
    • 0037077308 scopus 로고    scopus 로고
    • The immune modulator FTY720 targets sphingosine 1-phosphate receptors
    • V. Brinkmann The immune modulator FTY720 targets sphingosine 1-phosphate receptors J. Biol. Chem. 277 2002 21453 21457
    • (2002) J. Biol. Chem. , vol.277 , pp. 21453-21457
    • Brinkmann, V.1
  • 11
    • 0037066466 scopus 로고    scopus 로고
    • Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists
    • S. Mandala Alteration of lymphocyte trafficking by sphingosine-1- phosphate receptor agonists Science 296 2002 346 349
    • (2002) Science , vol.296 , pp. 346-349
    • Mandala, S.1
  • 12
    • 30044441314 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses
    • (in press)
    • Wei, S.H. et al. Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses. Nat. Immunol. (in press)
    • Nat. Immunol.
    • Wei, S.H.1
  • 13
    • 3242796768 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate receptor 1 promotes B cell localization in the splenic marginal zone
    • G. Cinamon Sphingosine 1-phosphate receptor 1 promotes B cell localization in the splenic marginal zone Nat. Immunol. 5 2004 713 720
    • (2004) Nat. Immunol. , vol.5 , pp. 713-720
    • Cinamon, G.1
  • 14
    • 1642580757 scopus 로고    scopus 로고
    • Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1
    • M. Matloubian Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1 Nature 427 2004 355 360
    • (2004) Nature , vol.427 , pp. 355-360
    • Matloubian, M.1
  • 15
    • 2442561611 scopus 로고    scopus 로고
    • 1, on T-cells controls thymic emigration
    • 1, on T-cells controls thymic emigration J. Biol. Chem. 279 2004 15396 15401
    • (2004) J. Biol. Chem. , vol.279 , pp. 15396-15401
    • Allende, M.L.1
  • 16
    • 2442679391 scopus 로고    scopus 로고
    • The immunosuppressant FTY720 down-regulates sphingosine 1-phosphate G protein-coupled receptors
    • M.H. Graler, and E.J. Goetzl The immunosuppressant FTY720 down-regulates sphingosine 1-phosphate G protein-coupled receptors FASEB J. 18 2004 551 553
    • (2004) FASEB J. , vol.18 , pp. 551-553
    • Graler, M.H.1    Goetzl, E.J.2
  • 17
    • 0034120178 scopus 로고    scopus 로고
    • FTY720 immunosuppression impairs effector T cell peripheral homing without affecting induction, expansion, and memory
    • D.D. Pinschewer FTY720 immunosuppression impairs effector T cell peripheral homing without affecting induction, expansion, and memory J. Immunol. 164 2000 5761 5770
    • (2000) J. Immunol. , vol.164 , pp. 5761-5770
    • Pinschewer, D.D.1
  • 18
    • 11144353922 scopus 로고    scopus 로고
    • 3, respectively, regulate lymphocyte recirculation and heart rate
    • 3, respectively, regulate lymphocyte recirculation and heart rate J. Biol. Chem. 279 2004 13839 13848
    • (2004) J. Biol. Chem. , vol.279 , pp. 13839-13848
    • Sanna, M.G.1
  • 19
    • 0036773971 scopus 로고    scopus 로고
    • FTY720: Targeting G-protein-coupled receptors for sphingosine 1-phosphate in transplantation and autoimmunity
    • V. Brinkmann, and K.R. Lynch FTY720: targeting G-protein-coupled receptors for sphingosine 1-phosphate in transplantation and autoimmunity Curr. Opin. Immunol. 14 2002 569 575
    • (2002) Curr. Opin. Immunol. , vol.14 , pp. 569-575
    • Brinkmann, V.1    Lynch, K.R.2
  • 20
    • 0037379202 scopus 로고    scopus 로고
    • Amelioration of experimental autoimmune encephalomyelitis in Lewis rats by FTY720 treatment
    • M. Fujino Amelioration of experimental autoimmune encephalomyelitis in Lewis rats by FTY720 treatment J. Pharmacol. Exp. Ther. 305 2003 70 77
    • (2003) J. Pharmacol. Exp. Ther. , vol.305 , pp. 70-77
    • Fujino, M.1
  • 21
    • 3242683494 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate receptor agonists attenuate relapsing-remitting experimental autoimmune encephalitis in SJL mice
    • M. Webb Sphingosine 1-phosphate receptor agonists attenuate relapsing-remitting experimental autoimmune encephalitis in SJL mice J. Neuroimmunol. 153 2004 108 121
    • (2004) J. Neuroimmunol. , vol.153 , pp. 108-121
    • Webb, M.1
  • 22
    • 0036830526 scopus 로고    scopus 로고
    • Thalamic neurodegeneration in multiple sclerosis
    • A. Cifelli Thalamic neurodegeneration in multiple sclerosis Ann. Neurol. 52 2002 650 653
    • (2002) Ann. Neurol. , vol.52 , pp. 650-653
    • Cifelli, A.1
  • 23
    • 0035941415 scopus 로고    scopus 로고
    • Sphingolipid mediators in cardiovascular cell biology and pathology
    • T. Levade Sphingolipid mediators in cardiovascular cell biology and pathology Circ. Res. 89 2001 957 968
    • (2001) Circ. Res. , vol.89 , pp. 957-968
    • Levade, T.1
  • 24
    • 0037704148 scopus 로고    scopus 로고
    • Lipid receptors in cardiovascular development
    • N. Osborne, and D.Y. Stainier Lipid receptors in cardiovascular development Annu. Rev. Physiol. 65 2003 23 43
    • (2003) Annu. Rev. Physiol. , vol.65 , pp. 23-43
    • Osborne, N.1    Stainier, D.Y.2
  • 25
    • 0033783522 scopus 로고    scopus 로고
    • Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation
    • Y. Liu Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation J. Clin. Invest. 106 2000 951 961
    • (2000) J. Clin. Invest. , vol.106 , pp. 951-961
    • Liu, Y.1
  • 26
    • 0242411518 scopus 로고    scopus 로고
    • 1 acts within endothelial cells to regulate vascular maturation
    • 1 acts within endothelial cells to regulate vascular maturation Blood 102 2003 3665 3667
    • (2003) Blood , vol.102 , pp. 3665-3667
    • Allende, M.L.1
  • 27
    • 3142744111 scopus 로고    scopus 로고
    • 3 function coordinately during embryonic angiogenesis
    • 3 function coordinately during embryonic angiogenesis J. Biol. Chem. 279 2004 29367 29373
    • (2004) J. Biol. Chem. , vol.279 , pp. 29367-29373
    • Kono, M.1
  • 28
    • 23944450417 scopus 로고    scopus 로고
    • Regulation of vascular reactivity by established and emerging GPCRs
    • J.J. Maguire, and A.P. Davenport Regulation of vascular reactivity by established and emerging GPCRs Trends Pharmacol. Sci. 26 2005 448 454
    • (2005) Trends Pharmacol. Sci. , vol.26 , pp. 448-454
    • Maguire, J.J.1    Davenport, A.P.2
  • 29
    • 0037162054 scopus 로고    scopus 로고
    • Athero- and thrombogenic actions of lysophosphatidic acid and sphingosine-1-phosphate
    • W. Siess Athero- and thrombogenic actions of lysophosphatidic acid and sphingosine-1-phosphate Biochim. Biophys. Acta 1582 2002 204 215
    • (2002) Biochim. Biophys. Acta , vol.1582 , pp. 204-215
    • Siess, W.1
  • 30
    • 0043020630 scopus 로고    scopus 로고
    • Subtype-selective antagonists of lysophosphatidic acid receptors inhibit platelet activation triggered by the lipid core of atherosclerotic plaques
    • E. Rother Subtype-selective antagonists of lysophosphatidic acid receptors inhibit platelet activation triggered by the lipid core of atherosclerotic plaques Circulation 108 2003 741 747
    • (2003) Circulation , vol.108 , pp. 741-747
    • Rother, E.1
  • 31
    • 0035860831 scopus 로고    scopus 로고
    • Role of the sphingosine 1-phosphate receptor EDG-1 in vascular smooth muscle cell proliferation and migration
    • M.J. Kluk, and T. Hla Role of the sphingosine 1-phosphate receptor EDG-1 in vascular smooth muscle cell proliferation and migration Circ. Res. 89 2001 496 502
    • (2001) Circ. Res. , vol.89 , pp. 496-502
    • Kluk, M.J.1    Hla, T.2
  • 32
    • 0035853107 scopus 로고    scopus 로고
    • Gene expression profiling of human stent-induced neointima by cDNA array analysis of microscopic specimens retrieved by helix cutter atherectomy: Detection of FK506-binding protein 12 upregulation
    • D. Zohlnhofer Gene expression profiling of human stent-induced neointima by cDNA array analysis of microscopic specimens retrieved by helix cutter atherectomy: detection of FK506-binding protein 12 upregulation Circulation 103 2001 1396 1402
    • (2001) Circulation , vol.103 , pp. 1396-1402
    • Zohlnhofer, D.1
  • 33
    • 0037178737 scopus 로고    scopus 로고
    • Comparison of sphingosine 1-phosphate-induced intracellular signaling pathways in vascular smooth muscles: Differential role in vasoconstriction
    • F. Coussin Comparison of sphingosine 1-phosphate-induced intracellular signaling pathways in vascular smooth muscles: differential role in vasoconstriction Circ. Res. 91 2002 151 157
    • (2002) Circ. Res. , vol.91 , pp. 151-157
    • Coussin, F.1
  • 34
    • 0038730511 scopus 로고    scopus 로고
    • 3 receptors mediate the potent constriction of cerebral arteries by sphingosine-1-phosphate
    • 3 receptors mediate the potent constriction of cerebral arteries by sphingosine-1-phosphate Eur. J. Pharmacol. 469 2003 125 134
    • (2003) Eur. J. Pharmacol. , vol.469 , pp. 125-134
    • Salomone, S.1
  • 38
    • 0344585385 scopus 로고    scopus 로고
    • Inhibition of Th1- and Th2-mediated airway inflammation by the sphingosine 1-phosphate receptor agonist FTY720
    • E. Sawicka Inhibition of Th1- and Th2-mediated airway inflammation by the sphingosine 1-phosphate receptor agonist FTY720 J. Immunol. 171 2003 6206 6214
    • (2003) J. Immunol. , vol.171 , pp. 6206-6214
    • Sawicka, E.1
  • 39
    • 5644287793 scopus 로고    scopus 로고
    • In vitro and in vivo modulation of vascular barrier integrity by sphingosine1-phosphate: Mechanistic insights
    • B. McVerry, and J. Garcia In vitro and in vivo modulation of vascular barrier integrity by sphingosine1-phosphate: mechanistic insights Cell. Signal. 17 2005 131 139
    • (2005) Cell. Signal. , vol.17 , pp. 131-139
    • McVerry, B.1    Garcia, J.2
  • 40
    • 0036285240 scopus 로고    scopus 로고
    • Combination treatment with FTY720 and CTLA4IgG preserves the respiratory epithelium and prevents obliterative disease in a murine airway model
    • K. Konishi Combination treatment with FTY720 and CTLA4IgG preserves the respiratory epithelium and prevents obliterative disease in a murine airway model J. Heart Lung Transplant. 21 2002 692 700
    • (2002) J. Heart Lung Transplant. , vol.21 , pp. 692-700
    • Konishi, K.1
  • 41
    • 0036035993 scopus 로고    scopus 로고
    • The roles of sphingosine-1-phosphate in asthma
    • P.S. Jolly The roles of sphingosine-1-phosphate in asthma Mol. Immunol. 38 2002 1239 1245
    • (2002) Mol. Immunol. , vol.38 , pp. 1239-1245
    • Jolly, P.S.1
  • 42
    • 0035348292 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate modulates human airway smooth muscle cell functions that promote inflammation and airway remodeling in asthma
    • A.J. Ammit Sphingosine 1-phosphate modulates human airway smooth muscle cell functions that promote inflammation and airway remodeling in asthma FASEB J. 15 2001 1212 1214
    • (2001) FASEB J. , vol.15 , pp. 1212-1214
    • Ammit, A.J.1
  • 43
    • 0036738085 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate as a therapeutic agent
    • S. Spiegel, and R. Kolesnick Sphingosine 1-phosphate as a therapeutic agent Leukemia 16 2002 1596 1602
    • (2002) Leukemia , vol.16 , pp. 1596-1602
    • Spiegel, S.1    Kolesnick, R.2
  • 44
    • 0034799675 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate promotes endothelial cell barrier integrity by Edg-dependent cytoskeletal rearrangement
    • J.G. Garcia Sphingosine 1-phosphate promotes endothelial cell barrier integrity by Edg-dependent cytoskeletal rearrangement J. Clin. Invest. 108 2001 689 701
    • (2001) J. Clin. Invest. , vol.108 , pp. 689-701
    • Garcia, J.G.1
  • 45
    • 21544473152 scopus 로고    scopus 로고
    • 3 receptor-induced reorganization of epithelial tight junctions compromises lung barrier integrity and is potentiated by TNF
    • 3 receptor-induced reorganization of epithelial tight junctions compromises lung barrier integrity and is potentiated by TNF Proc. Natl. Acad. Sci. U. S. A. 102 2005 9270 9275
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 9270-9275
    • Gon, Y.1
  • 46
    • 0036494268 scopus 로고    scopus 로고
    • Marked prevention of tumor growth and metastasis by a novel immunosuppressive agent, FTY720, in mouse breast cancer models
    • H. Azuma Marked prevention of tumor growth and metastasis by a novel immunosuppressive agent, FTY720, in mouse breast cancer models Cancer Res. 62 2002 1410 1419
    • (2002) Cancer Res. , vol.62 , pp. 1410-1419
    • Azuma, H.1
  • 47
    • 10344231428 scopus 로고    scopus 로고
    • FTY720 induces apoptosis of human hepatoma cell lines through PI3-K-mediated Akt dephosphorylation
    • T.K. Lee FTY720 induces apoptosis of human hepatoma cell lines through PI3-K-mediated Akt dephosphorylation Carcinogenesis 25 2004 2397 2405
    • (2004) Carcinogenesis , vol.25 , pp. 2397-2405
    • Lee, T.K.1
  • 48
    • 17844382139 scopus 로고    scopus 로고
    • G protein-coupled lysophosphatidic acid receptors stimulate proliferation of colon cancer cells through the β-catenin pathway
    • M. Yang G protein-coupled lysophosphatidic acid receptors stimulate proliferation of colon cancer cells through the β-catenin pathway Proc. Natl. Acad. Sci. U. S. A. 102 2005 6027 6032
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 6027-6032
    • Yang, M.1
  • 49
    • 0034735916 scopus 로고    scopus 로고
    • An oncogenic role of sphingosine kinase
    • P. Xia An oncogenic role of sphingosine kinase Curr. Biol. 10 2000 1527 1530
    • (2000) Curr. Biol. , vol.10 , pp. 1527-1530
    • Xia, P.1
  • 50
    • 0141507968 scopus 로고    scopus 로고
    • Discovery and evaluation of inhibitors of human sphingosine kinase
    • K.J. French Discovery and evaluation of inhibitors of human sphingosine kinase Cancer Res. 63 2003 5962 5969
    • (2003) Cancer Res. , vol.63 , pp. 5962-5969
    • French, K.J.1
  • 51
    • 0042887042 scopus 로고    scopus 로고
    • The emerging role of lysophosphatidic acid in cancer
    • G.B. Mills, and W.H. Moolenaar The emerging role of lysophosphatidic acid in cancer Nat. Rev. Cancer 3 2003 582 591
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 582-591
    • Mills, G.B.1    Moolenaar, W.H.2
  • 52
    • 0037131366 scopus 로고    scopus 로고
    • Identification of human plasma lysophospholipase D, a lysophosphatidic acid-producing enzyme, as autotaxin, a multifunctional phosphodiesterase
    • A. Tokumura Identification of human plasma lysophospholipase D, a lysophosphatidic acid-producing enzyme, as autotaxin, a multifunctional phosphodiesterase J. Biol. Chem. 277 2002 39436 39442
    • (2002) J. Biol. Chem. , vol.277 , pp. 39436-39442
    • Tokumura, A.1
  • 53
    • 1542359873 scopus 로고    scopus 로고
    • Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production
    • M. Umezu-Goto Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production J. Cell Biol. 158 2002 227 233
    • (2002) J. Cell Biol. , vol.158 , pp. 227-233
    • Umezu-Goto, M.1
  • 54
    • 23844465897 scopus 로고    scopus 로고
    • Proteolytic maturation and activation of autotaxin (NPP2), a secreted metastasis-enhancing lysophospholipase D
    • S. Jansen Proteolytic maturation and activation of autotaxin (NPP2), a secreted metastasis-enhancing lysophospholipase D J. Cell Sci. 118 2005 3081 3089
    • (2005) J. Cell Sci. , vol.118 , pp. 3081-3089
    • Jansen, S.1
  • 55
    • 0034642507 scopus 로고    scopus 로고
    • Autotaxin (ATX), a potent tumor motogen, augments invasive and metastatic potential of ras-transformed cells
    • S.W. Nam Autotaxin (ATX), a potent tumor motogen, augments invasive and metastatic potential of ras-transformed cells Oncogene 19 2000 241 247
    • (2000) Oncogene , vol.19 , pp. 241-247
    • Nam, S.W.1
  • 56
    • 0035884290 scopus 로고    scopus 로고
    • Autotaxin (NPP-2), a metastasis-enhancing motogen, is an angiogenic factor
    • S.W. Nam Autotaxin (NPP-2), a metastasis-enhancing motogen, is an angiogenic factor Cancer Res. 61 2001 6938 6944
    • (2001) Cancer Res. , vol.61 , pp. 6938-6944
    • Nam, S.W.1
  • 57
    • 10744223639 scopus 로고    scopus 로고
    • Lysophosphatidic acid (LPA) in malignant ascites stimulates motility of human pancreatic cancer cells through LPA1
    • T. Yamada Lysophosphatidic acid (LPA) in malignant ascites stimulates motility of human pancreatic cancer cells through LPA1 J. Biol. Chem. 279 2004 6595 6605
    • (2004) J. Biol. Chem. , vol.279 , pp. 6595-6605
    • Yamada, T.1
  • 58
    • 0037134949 scopus 로고    scopus 로고
    • Plasma lysophosphatidic acid concentration and ovarian cancer
    • D.L. Baker Plasma lysophosphatidic acid concentration and ovarian cancer J. Am. Med. Assoc. 287 2002 3081 3082
    • (2002) J. Am. Med. Assoc. , vol.287 , pp. 3081-3082
    • Baker, D.L.1
  • 59
    • 3142660497 scopus 로고    scopus 로고
    • Lysophospholipids are potential biomarkers of ovarian cancer
    • R. Sutphen Lysophospholipids are potential biomarkers of ovarian cancer Cancer Epidemiol. Biomarkers Prev. 13 2004 1185 1191
    • (2004) Cancer Epidemiol. Biomarkers Prev. , vol.13 , pp. 1185-1191
    • Sutphen, R.1
  • 60
    • 0036196268 scopus 로고    scopus 로고
    • Lysophosphatidic acid and its role in reproduction
    • L.T. Budnik, and A.K. Mukhopadhyay Lysophosphatidic acid and its role in reproduction Biol. Reprod. 66 2002 859 865
    • (2002) Biol. Reprod. , vol.66 , pp. 859-865
    • Budnik, L.T.1    Mukhopadhyay, A.K.2
  • 61
    • 3142685946 scopus 로고    scopus 로고
    • Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling
    • M. Inoue Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling Nat. Med. 10 2004 712 718
    • (2004) Nat. Med. , vol.10 , pp. 712-718
    • Inoue, M.1
  • 62
    • 0033955969 scopus 로고    scopus 로고
    • Vzg-1/lysophosphatidic acid-receptor involved in peripheral pain transmission
    • K. Renback Vzg-1/lysophosphatidic acid-receptor involved in peripheral pain transmission Mol. Brain Res. 75 2000 350 354
    • (2000) Mol. Brain Res. , vol.75 , pp. 350-354
    • Renback, K.1
  • 63
    • 0344417883 scopus 로고    scopus 로고
    • Lysophosphatidic acid-induced, pertussis toxin-sensitive nociception through a substance P release from peripheral nerve endings in mice
    • K. Renback Lysophosphatidic acid-induced, pertussis toxin-sensitive nociception through a substance P release from peripheral nerve endings in mice Neurosci. Lett. 270 1999 59 61
    • (1999) Neurosci. Lett. , vol.270 , pp. 59-61
    • Renback, K.1
  • 64
    • 0031963295 scopus 로고    scopus 로고
    • Central demyelination of the Vth nerve root in trigeminal neuralgia associated with vascular compression
    • S. Love Central demyelination of the Vth nerve root in trigeminal neuralgia associated with vascular compression Brain Pathol. 8 1998 1 11
    • (1998) Brain Pathol. , vol.8 , pp. 1-11
    • Love, S.1
  • 65
    • 0034981484 scopus 로고    scopus 로고
    • Schizophrenia as a neurodevelopmental disorder
    • R.M. Bilder Schizophrenia as a neurodevelopmental disorder Curr. Opin. Pyschiatry 14 2001 9 15
    • (2001) Curr. Opin. Pyschiatry , vol.14 , pp. 9-15
    • Bilder, R.M.1
  • 66
    • 0024583797 scopus 로고
    • Quantification, characterization and fatty acid composition of lysophosphatidic acid in different rat tissues
    • A.K. Das, and A.K. Hajra Quantification, characterization and fatty acid composition of lysophosphatidic acid in different rat tissues Lipids 24 1989 329 333
    • (1989) Lipids , vol.24 , pp. 329-333
    • Das, A.K.1    Hajra, A.K.2
  • 67
    • 0031042001 scopus 로고    scopus 로고
    • Distribution of sphingosine 1-phosphate, a bioactive sphingolipid, in rat tissues
    • Y. Yatomi Distribution of sphingosine 1-phosphate, a bioactive sphingolipid, in rat tissues FEBS Lett. 404 1997 173 174
    • (1997) FEBS Lett. , vol.404 , pp. 173-174
    • Yatomi, Y.1
  • 68
    • 0034551689 scopus 로고    scopus 로고
    • Lysophosphatidic acid (LPA) is a novel extracellular regulator of cortical neuroblast morphology
    • N. Fukushima Lysophosphatidic acid (LPA) is a novel extracellular regulator of cortical neuroblast morphology Dev. Biol. 228 2000 6 18
    • (2000) Dev. Biol. , vol.228 , pp. 6-18
    • Fukushima, N.1
  • 69
    • 0028849449 scopus 로고
    • Molecular cloning and chromosomal assignment of the human brain-type phosphodiesterase I/nucleotide pyrophosphatase gene (PDNP2)
    • H. Kawagoe Molecular cloning and chromosomal assignment of the human brain-type phosphodiesterase I/nucleotide pyrophosphatase gene (PDNP2) Genomics 30 1995 380 384
    • (1995) Genomics , vol.30 , pp. 380-384
    • Kawagoe, H.1
  • 70
    • 0037201937 scopus 로고    scopus 로고
    • Embryonic brain expression analysis of lysophospholipid receptor genes suggests roles for s1p(1) in neurogenesis and s1p(1-3) in angiogenesis
    • C. McGiffert Embryonic brain expression analysis of lysophospholipid receptor genes suggests roles for s1p(1) in neurogenesis and s1p(1-3) in angiogenesis FEBS Lett. 531 2002 103 108
    • (2002) FEBS Lett. , vol.531 , pp. 103-108
    • McGiffert, C.1
  • 71
    • 0032494278 scopus 로고    scopus 로고
    • Lysophosphatidic acid receptor gene vzg-1/lpA1/edg-2 is expressed by mature oligodendrocytes during myelination in the postnatal murine brain
    • J.A. Weiner Lysophosphatidic acid receptor gene vzg-1/lpA1/edg-2 is expressed by mature oligodendrocytes during myelination in the postnatal murine brain J. Comp. Neurol. 398 1998 587 598
    • (1998) J. Comp. Neurol. , vol.398 , pp. 587-598
    • Weiner, J.A.1
  • 72
    • 0034162958 scopus 로고    scopus 로고
    • Genomic characterization of the lysophosphatidic acid receptor gene, lp(A2)/Edg4, and identification of a frameshift mutation in a previously characterized cDNA
    • J.J. Contos, and J. Chun Genomic characterization of the lysophosphatidic acid receptor gene, lp(A2)/Edg4, and identification of a frameshift mutation in a previously characterized cDNA Genomics 64 2000 155 169
    • (2000) Genomics , vol.64 , pp. 155-169
    • Contos, J.J.1    Chun, J.2
  • 73
    • 0344011597 scopus 로고    scopus 로고
    • Non-proliferative effects of lysophosphatidic acid enhance cortical growth and folding
    • M.A. Kingsbury Non-proliferative effects of lysophosphatidic acid enhance cortical growth and folding Nat. Neurosci. 6 2003 1292 1299
    • (2003) Nat. Neurosci. , vol.6 , pp. 1292-1299
    • Kingsbury, M.A.1
  • 74
    • 0034700050 scopus 로고    scopus 로고
    • Requirement for the lpA1 lysophosphatidic acid receptor gene in normal suckling behavior
    • J.J. Contos Requirement for the lpA1 lysophosphatidic acid receptor gene in normal suckling behavior Proc. Natl. Acad. Sci. U. S. A. 97 2000 13384 13389
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , pp. 13384-13389
    • Contos, J.J.1
  • 76
    • 0345863390 scopus 로고    scopus 로고
    • LPA1 receptor-deficient mice have phenotypic changes observed in psychiatric disease
    • S.M. Harrison LPA1 receptor-deficient mice have phenotypic changes observed in psychiatric disease Mol. Cell. Neurosci. 24 2003 1170 1179
    • (2003) Mol. Cell. Neurosci. , vol.24 , pp. 1170-1179
    • Harrison, S.M.1
  • 77
    • 0026581360 scopus 로고
    • Gating and habituation of the startle reflex in schizophrenic patients
    • D.L. Braff Gating and habituation of the startle reflex in schizophrenic patients Arch. Gen. Psychiatry 49 1992 206 215
    • (1992) Arch. Gen. Psychiatry , vol.49 , pp. 206-215
    • Braff, D.L.1
  • 78
    • 2542451853 scopus 로고    scopus 로고
    • Neuregulin 1-erbB signaling and the molecular/cellular basis of schizophrenia
    • G. Corfas Neuregulin 1-erbB signaling and the molecular/cellular basis of schizophrenia Nat. Neurosci. 7 2004 575 580
    • (2004) Nat. Neurosci. , vol.7 , pp. 575-580
    • Corfas, G.1
  • 79
    • 0035836642 scopus 로고    scopus 로고
    • Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia
    • Y. Hakak Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia Proc. Natl. Acad. Sci. U. S. A. 98 2001 4746 4751
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , pp. 4746-4751
    • Hakak, Y.1
  • 80
    • 0031927229 scopus 로고    scopus 로고
    • A rat G protein-coupled receptor selectively expressed in myelin-forming cells
    • J. Allard A rat G protein-coupled receptor selectively expressed in myelin-forming cells Eur. J. Neurosci. 10 1998 1045 1053
    • (1998) Eur. J. Neurosci. , vol.10 , pp. 1045-1053
    • Allard, J.1
  • 81
    • 18344397194 scopus 로고    scopus 로고
    • 3-mediated lysophosphatidic acid signalling in embryo implantation and spacing
    • 3-mediated lysophosphatidic acid signalling in embryo implantation and spacing Nature 435 2005 104 108
    • (2005) Nature , vol.435 , pp. 104-108
    • Ye, X.1
  • 82
    • 0033034459 scopus 로고    scopus 로고
    • Production of lysophosphatidic acids by lysophospholipase D in human follicular fluids of in vitro fertilization patients
    • A. Tokumura Production of lysophosphatidic acids by lysophospholipase D in human follicular fluids of in vitro fertilization patients Biol. Reprod. 61 1999 195 199
    • (1999) Biol. Reprod. , vol.61 , pp. 195-199
    • Tokumura, A.1
  • 83
    • 0033786639 scopus 로고    scopus 로고
    • Oocyte apoptosis is suppressed by disruption of the acid sphingomyelinase gene or by sphingosine-1-phosphate therapy
    • Y. Morita Oocyte apoptosis is suppressed by disruption of the acid sphingomyelinase gene or by sphingosine-1-phosphate therapy Nat. Med. 6 2000 1109 1114
    • (2000) Nat. Med. , vol.6 , pp. 1109-1114
    • Morita, Y.1
  • 84
    • 0034102433 scopus 로고    scopus 로고
    • Sphingolipid regulation of female gonadal cell apoptosis
    • Y. Morita, and J.L. Tilly Sphingolipid regulation of female gonadal cell apoptosis Ann. N. Y. Acad. Sci. 905 2000 209 220
    • (2000) Ann. N. Y. Acad. Sci. , vol.905 , pp. 209-220
    • Morita, Y.1    Tilly, J.L.2
  • 85
    • 0037203319 scopus 로고    scopus 로고
    • Sphingolipids, apoptosis, cancer treatments and the ovary: Investigating a crime against female fertility
    • J.L. Tilly, and R.N. Kolesnick Sphingolipids, apoptosis, cancer treatments and the ovary: investigating a crime against female fertility Biochim. Biophys. Acta 1585 2002 135 138
    • (2002) Biochim. Biophys. Acta , vol.1585 , pp. 135-138
    • Tilly, J.L.1    Kolesnick, R.N.2
  • 86
    • 0034926280 scopus 로고    scopus 로고
    • Oxytocin and lysophosphatidic acid induce stress fiber formation in human myometrial cells via a pathway involving Rho-kinase
    • W. Gogarten Oxytocin and lysophosphatidic acid induce stress fiber formation in human myometrial cells via a pathway involving Rho-kinase Biol. Reprod. 65 2001 401 406
    • (2001) Biol. Reprod. , vol.65 , pp. 401-406
    • Gogarten, W.1
  • 87
    • 0018909989 scopus 로고
    • Stimulatory effect of lysophosphatidic acids on uterine smooth muscles of non-pregnant rats
    • A. Tokumura Stimulatory effect of lysophosphatidic acids on uterine smooth muscles of non-pregnant rats Arch. Int. Pharmacodyn. Ther. 245 1980 74 83
    • (1980) Arch. Int. Pharmacodyn. Ther. , vol.245 , pp. 74-83
    • Tokumura, A.1
  • 88
    • 0017366933 scopus 로고
    • Evidence for a role for prosaglandins in the initiation of blastocyst implantation in the rat
    • T.G. Kennedy Evidence for a role for prosaglandins in the initiation of blastocyst implantation in the rat Biol. Reprod. 16 1977 286 291
    • (1977) Biol. Reprod. , vol.16 , pp. 286-291
    • Kennedy, T.G.1
  • 89
    • 0022293197 scopus 로고
    • Involvement of prostaglandins in implantation in the pregnant mouse
    • K. Kinoshita Involvement of prostaglandins in implantation in the pregnant mouse Adv. Prostaglandin Thromboxane Leukot. Res. 15 1985 605 607
    • (1985) Adv. Prostaglandin Thromboxane Leukot. Res. , vol.15 , pp. 605-607
    • Kinoshita, K.1
  • 90
    • 0033600761 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a novel human G-protein-coupled receptor, EDG7, for lysophosphatidic acid
    • K. Bandoh Molecular cloning and characterization of a novel human G-protein-coupled receptor, EDG7, for lysophosphatidic acid J. Biol. Chem. 274 1999 27776 27785
    • (1999) J. Biol. Chem. , vol.274 , pp. 27776-27785
    • Bandoh, K.1
  • 91
    • 18244420024 scopus 로고    scopus 로고
    • Role of phospholipases during sperm acrosomal exocytosis
    • E.R. Roldan Role of phospholipases during sperm acrosomal exocytosis Front. Biosci. 3 1998 D1109 D1119
    • (1998) Front. Biosci. , vol.3
    • Roldan, E.R.1
  • 92
    • 0346996444 scopus 로고    scopus 로고
    • Mice with transgenic overexpression of lipid phosphate phosphatase-1 display multiple organotypic deficits without alteration in circulating lysophosphatidate level
    • J. Yue Mice with transgenic overexpression of lipid phosphate phosphatase-1 display multiple organotypic deficits without alteration in circulating lysophosphatidate level Cell. Signal. 16 2004 385 399
    • (2004) Cell. Signal. , vol.16 , pp. 385-399
    • Yue, J.1
  • 93
    • 2342430250 scopus 로고    scopus 로고
    • Obesity, insulin resistance, and cardiovascular disease
    • G. Reaven Obesity, insulin resistance, and cardiovascular disease Recent Prog. Horm. Res. 59 2004 207 223
    • (2004) Recent Prog. Horm. Res. , vol.59 , pp. 207-223
    • Reaven, G.1
  • 94
    • 13844314223 scopus 로고    scopus 로고
    • Fat cells: Afferent and efferent messages define new approaches to treat obesity
    • M. Lafontan Fat cells: afferent and efferent messages define new approaches to treat obesity Annu. Rev. Pharmacol. Toxicol. 45 2005 119 146
    • (2005) Annu. Rev. Pharmacol. Toxicol. , vol.45 , pp. 119-146
    • Lafontan, M.1
  • 95
    • 0035004560 scopus 로고    scopus 로고
    • Lysophosphatidic acid synthesis and release
    • C. Pages Lysophosphatidic acid synthesis and release Prostaglandins Other Lipid Mediat. 64 2001 1 10
    • (2001) Prostaglandins Other Lipid Mediat. , vol.64 , pp. 1-10
    • Pages, C.1
  • 96
    • 17644413626 scopus 로고    scopus 로고
    • Lysophosphatidic acid inhibits adipocyte differentiation via lysophosphatidic acid 1 receptor-dependent down-regulation of peroxisome proliferator-activated receptor γ2
    • M.F. Simon Lysophosphatidic acid inhibits adipocyte differentiation via lysophosphatidic acid 1 receptor-dependent down-regulation of peroxisome proliferator-activated receptor γ2 J. Biol. Chem. 280 2005 14656 14662
    • (2005) J. Biol. Chem. , vol.280 , pp. 14656-14662
    • Simon, M.F.1
  • 97
    • 0038043168 scopus 로고    scopus 로고
    • Autotaxin is released from adipocytes, catalyzes lysophosphatidic acid synthesis, and activates preadipocyte proliferation. Up-regulated expression with adipocyte differentiation and obesity
    • G. Ferry Autotaxin is released from adipocytes, catalyzes lysophosphatidic acid synthesis, and activates preadipocyte proliferation. Up-regulated expression with adipocyte differentiation and obesity J. Biol. Chem. 278 2003 18162 18169
    • (2003) J. Biol. Chem. , vol.278 , pp. 18162-18169
    • Ferry, G.1
  • 98
    • 0037422595 scopus 로고    scopus 로고
    • Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARγ agonist
    • T.M. McIntyre Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARγ agonist Proc. Natl. Acad. Sci. U. S. A. 100 2003 131 136
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 131-136
    • McIntyre, T.M.1
  • 99
    • 0035966064 scopus 로고    scopus 로고
    • 1 (EDG2) phospholipid growth factor receptors
    • 1 (EDG2) phospholipid growth factor receptors J. Biol. Chem. 276 2001 49213 49220
    • (2001) J. Biol. Chem. , vol.276 , pp. 49213-49220
    • Wang, D.A.1
  • 100
    • 0141570981 scopus 로고    scopus 로고
    • Ki16425, a subtype-selective antagonist for EDG-family lysophosphatidic acid receptors
    • H. Ohta Ki16425, a subtype-selective antagonist for EDG-family lysophosphatidic acid receptors Mol. Pharmacol. 64 2003 994 1005
    • (2003) Mol. Pharmacol. , vol.64 , pp. 994-1005
    • Ohta, H.1
  • 101
    • 0036434445 scopus 로고    scopus 로고
    • Enhancement of sphingosine 1-phosphate-induced migration of vascular endothelial cells and smooth muscle cells by an EDG-5 antagonist
    • M. Osada Enhancement of sphingosine 1-phosphate-induced migration of vascular endothelial cells and smooth muscle cells by an EDG-5 antagonist Biochem. Biophys. Res. Commun. 299 2002 483 487
    • (2002) Biochem. Biophys. Res. Commun. , vol.299 , pp. 483-487
    • Osada, M.1
  • 102
    • 0036205659 scopus 로고    scopus 로고
    • First human trial of FTY720, a novel immunomodulator, in stable renal transplant patients
    • K. Budde First human trial of FTY720, a novel immunomodulator, in stable renal transplant patients J. Am. Soc. Nephrol. 13 2002 1073 1083
    • (2002) J. Am. Soc. Nephrol. , vol.13 , pp. 1073-1083
    • Budde, K.1
  • 103
    • 15244343497 scopus 로고    scopus 로고
    • Platelet-derived lysophosphatidic acid supports the progression of osteolytic bone metastases in breast cancer
    • A. Boucharaba Platelet-derived lysophosphatidic acid supports the progression of osteolytic bone metastases in breast cancer J. Clin. Invest. 114 2004 1714 1725
    • (2004) J. Clin. Invest. , vol.114 , pp. 1714-1725
    • Boucharaba, A.1
  • 104
    • 7444219945 scopus 로고    scopus 로고
    • Chronic pain and microglia: The role of ATP
    • K. Inoue Chronic pain and microglia: the role of ATP Novartis Found. Symp. 261 2004 55 64
    • (2004) Novartis Found. Symp. , vol.261 , pp. 55-64
    • Inoue, K.1
  • 105
    • 13944280988 scopus 로고    scopus 로고
    • G protein mediated signaling pathways in lysophospholipid induced cell proliferation and survival
    • J. Radeff-Huang G protein mediated signaling pathways in lysophospholipid induced cell proliferation and survival J. Cell. Biochem. 92 2004 949 966
    • (2004) J. Cell. Biochem. , vol.92 , pp. 949-966
    • Radeff-Huang, J.1
  • 106
    • 2342437623 scopus 로고    scopus 로고
    • Lysophosphatidic acid and autotaxin stimulate cell motility of neoplastic and non-neoplastic cells through LPA1
    • K. Hama Lysophosphatidic acid and autotaxin stimulate cell motility of neoplastic and non-neoplastic cells through LPA1 J. Biol. Chem. 279 2004 17634 17639
    • (2004) J. Biol. Chem. , vol.279 , pp. 17634-17639
    • Hama, K.1
  • 107
    • 27144452068 scopus 로고    scopus 로고
    • Role of p38 mitogen-activated kinase and c-Jun terminal kinase in migration response to lysophosphatidic acid and sphingosine-1-phosphate in glioma cells
    • E. Malchinkhuu Role of p38 mitogen-activated kinase and c-Jun terminal kinase in migration response to lysophosphatidic acid and sphingosine-1- phosphate in glioma cells Oncogene 24 2005 6676 6688
    • (2005) Oncogene , vol.24 , pp. 6676-6688
    • Malchinkhuu, E.1
  • 108
    • 3042523481 scopus 로고    scopus 로고
    • Lysophosphatidic acid stimulates ovarian cancer cell migration via a Ras-MEK kinase 1 pathway
    • D. Bian Lysophosphatidic acid stimulates ovarian cancer cell migration via a Ras-MEK kinase 1 pathway Cancer Res. 64 2004 4209 4217
    • (2004) Cancer Res. , vol.64 , pp. 4209-4217
    • Bian, D.1
  • 109
    • 15444373513 scopus 로고    scopus 로고
    • PTEN as an effector in the signaling of antimigratory G protein-coupled receptor
    • T. Sanchez PTEN as an effector in the signaling of antimigratory G protein-coupled receptor Proc. Natl. Acad. Sci. U. S. A. 102 2005 4312 4317
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 4312-4317
    • Sanchez, T.1
  • 110
    • 12144285600 scopus 로고    scopus 로고
    • Proteases, extracellular matrix, and cancer: A workshop of the path B study section
    • Y.A. DeClerck Proteases, extracellular matrix, and cancer: a workshop of the path B study section Am. J. Pathol. 164 2004 1131 1139
    • (2004) Am. J. Pathol. , vol.164 , pp. 1131-1139
    • Declerck, Y.A.1
  • 111
    • 15444368022 scopus 로고    scopus 로고
    • Signaling mechanisms responsible for lysophosphatidic acid-induced urokinase plasminogen activator expression in ovarian cancer cells
    • H. Li Signaling mechanisms responsible for lysophosphatidic acid-induced urokinase plasminogen activator expression in ovarian cancer cells J. Biol. Chem. 280 2005 10564 10571
    • (2005) J. Biol. Chem. , vol.280 , pp. 10564-10571
    • Li, H.1
  • 112
    • 0034705477 scopus 로고    scopus 로고
    • 2+ influx in human platelets
    • 2+ influx in human platelets J. Biol. Chem. 275 2000 19159 19166
    • (2000) J. Biol. Chem. , vol.275 , pp. 19159-19166
    • Maschberger, P.1
  • 113
    • 0035800886 scopus 로고    scopus 로고
    • Phenotypic modulation of vascular smooth muscle cells induced by unsaturated lysophosphatidic acids
    • K. Hayashi Phenotypic modulation of vascular smooth muscle cells induced by unsaturated lysophosphatidic acids Circ. Res. 89 2001 251 258
    • (2001) Circ. Res. , vol.89 , pp. 251-258
    • Hayashi, K.1
  • 114
    • 9644260561 scopus 로고    scopus 로고
    • The role of sphingosine-1-phosphate in smooth muscle contraction
    • K.R. Watterson The role of sphingosine-1-phosphate in smooth muscle contraction Cell. Signal. 17 2005 289 298
    • (2005) Cell. Signal. , vol.17 , pp. 289-298
    • Watterson, K.R.1
  • 115
    • 0033609118 scopus 로고    scopus 로고
    • Schwann cell survival mediated by the signaling phospholipid lysophosphatidic acid
    • J.A. Weiner, and J. Chun Schwann cell survival mediated by the signaling phospholipid lysophosphatidic acid Proc. Natl. Acad. Sci. U. S. A. 96 1999 5233 5238
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 5233-5238
    • Weiner, J.A.1    Chun, J.2
  • 116
    • 0038660660 scopus 로고    scopus 로고
    • Lysophosphatidic acid promotes survival and differentiation of rat Schwann cells
    • Y. Li Lysophosphatidic acid promotes survival and differentiation of rat Schwann cells J. Biol. Chem. 278 2003 9585 9591
    • (2003) J. Biol. Chem. , vol.278 , pp. 9585-9591
    • Li, Y.1
  • 117
    • 0343820101 scopus 로고    scopus 로고
    • Role of lysophosphatidic acid and rho in glioma cell motility
    • T.J. Manning Jr Role of lysophosphatidic acid and rho in glioma cell motility Cell Motil. Cytoskeleton 45 2000 185 199
    • (2000) Cell Motil. Cytoskeleton , vol.45 , pp. 185-199
    • Manning Jr., T.J.1
  • 118
    • 0036679066 scopus 로고    scopus 로고
    • 2+-α-actinin and polymerization by rho
    • 2+-α-actinin and polymerization by rho Mol. Biol. Cell 13 2002 2692 2705
    • (2002) Mol. Biol. Cell , vol.13 , pp. 2692-2705
    • Fukushima, N.1
  • 119
    • 0031008341 scopus 로고    scopus 로고
    • Lysophosphatidic acid induces a sustained elevation of neuronal intracellular calcium
    • F.W. Holtsberg Lysophosphatidic acid induces a sustained elevation of neuronal intracellular calcium J. Neurochem. 69 1997 68 75
    • (1997) J. Neurochem. , vol.69 , pp. 68-75
    • Holtsberg, F.W.1
  • 120
    • 0035884770 scopus 로고    scopus 로고
    • Regulation of Schwann cell morphology and adhesion by receptor-mediated lysophosphatidic acid signaling
    • J.A. Weiner Regulation of Schwann cell morphology and adhesion by receptor-mediated lysophosphatidic acid signaling J. Neurosci. 21 2001 7069 7078
    • (2001) J. Neurosci. , vol.21 , pp. 7069-7078
    • Weiner, J.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.