Two-dimensional combinatorial screening identifies specific 6′-acylated kanamycin A- and 6′-acylated neamine-RNA hairpin interactions

Biochemistry

Volumn 47, Issue 48, 2008, Pages 12670-12679

  Aminova, Olga ^a   Paul, Dustin J ^a   Childs Disney, Jessica L ^b   Disney, Matthew D ^a  

^a UNIVERSITY AT BUFFALO   (United States)

^b CANISIUS COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLOW INTERACTIONS; LIGANDS; NUCLEOTIDES; RANGE FINDING; RNA; TWO DIMENSIONAL;

COMBINATORIAL SCREENINGS; HAIRPIN LOOPS; KANAMYCIN; LIGAND BINDS; LIGAND INTERACTIONS; SECONDARY STRUCTURE PREDICTIONS; SMALL MOLECULES;

NUCLEIC ACIDS;

KANAMYCIN A DERIVATIVE; NEAMINE; RNA;

ACYLATION; ARTICLE; COMBINATORIAL CHEMISTRY; LIGAND BINDING; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN SECONDARY STRUCTURE; PROTEIN TARGETING; RNA BINDING;

ACYLATION; ADENINE; BASE SEQUENCE; COMBINATORIAL CHEMISTRY TECHNIQUES; CYTOSINE; DRUG EVALUATION, PRECLINICAL; FRAMYCETIN; INVERTED REPEAT SEQUENCES; KANAMYCIN; LIGANDS; RNA; SUBSTRATE SPECIFICITY;

EID: 57049107410     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi8012615     Document Type: Article

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