Antibiotic inhibition of RNA catalysis: Neomycin B binds to the catalytic core of the td group I intron displacing essential metal ions

Journal of Molecular Biology

Volumn 282, Issue 3, 1998, Pages 557-569

  Hoch, I ^a   Berens, C ^a   Westhof, E ^b   Schroeder, R ^a  

^a Vienna Biocenter   (Austria)

^b INSTITUT DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

Antibiotics; Catalytic RNA; Group I introns; Metal ions; Neomycin B

Indexed keywords

ANTIBIOTIC AGENT; FRAMYCETIN; HYDROXYL RADICAL; METAL ION; RIBOZYME; THYMIDYLATE SYNTHASE;

ARTICLE; BACTERIOPHAGE T4; BINDING SITE; DNA FOOTPRINTING; DRUG INHIBITION; ELECTRICITY; GENETIC CODE; INTRON; PRIORITY JOURNAL;

T4 PHAGE;

EID: 0032566484     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1998.2035     Document Type: Article

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