Mitochondrial DNA damage and its potential role in retinal degeneration

Progress in Retinal and Eye Research

Volumn 27, Issue 6, 2008, Pages 596-607

  Jarrett, Stuart G ^a   Lin, Haijiang ^b   Godley, Bernard F ^b   Boulton, Michael E ^c  

^a UNIVERSITY OF KENTUCKY   (United States)

^b University of Texas Medical Branch School of Medicine   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

Age related macular degeneration; Base excision repair; Mitochondria; Oxidative stress; Retinal degeneration; Retinal pigment epithelium

Indexed keywords

ALPHA CRYSTALLIN; ANTIOXIDANT; ASCORBIC ACID; CARNITINE; DNA DIRECTED DNA POLYMERASE GAMMA; GLUTATHIONE TRANSFERASE; HYDROXYLAMINE; MANGANESE SUPEROXIDE DISMUTASE; MELATONIN; MITOCHONDRIAL DNA; N TERT BUTYL ALPHA PHENYLNITRONE; N TERT BUTYL HYDROXYLAMINE; PHOSPHONIUM DERIVATIVE; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; RESVERATROL; UNCLASSIFIED DRUG;

ADAPTATION; AGING; APOPTOSIS; CELL DEGENERATION; CELL FUNCTION; CELL SURVIVAL; CHEMOPROPHYLAXIS; DIABETIC RETINOPATHY; DIETARY INTAKE; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA DAMAGE; DNA REPAIR; ENZYME MECHANISM; EXCISION REPAIR; GENE DELETION; GENE OVEREXPRESSION; GENE TARGETING; GENOME; GLAUCOMA; HETEROPLASMY; HUMAN; LIPID PEROXIDATION; MISMATCH REPAIR; MITOCHONDRION; NONHUMAN; OPEN ANGLE GLAUCOMA; OXIDATIVE STRESS; PARKINSON DISEASE; PATHOGENESIS; PHAGOCYTOSIS; PHOTORECEPTOR; PIGMENT EPITHELIUM; POINT MUTATION; PRIORITY JOURNAL; RETINA CELL; RETINA MACULA AGE RELATED DEGENERATION; RETINA NEUROEPITHELIAL LAYER; REVIEW; SUBRETINAL NEOVASCULARIZATION; UPREGULATION;

ANIMALS; DNA DAMAGE; DNA REPAIR; DNA, MITOCHONDRIAL; GENOMIC INSTABILITY; HUMANS; OXIDATIVE STRESS; RETINAL DEGENERATION; RETINAL PIGMENT EPITHELIUM;

EID: 55649114157     PISSN: 13509462     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.preteyeres.2008.09.001     Document Type: Review

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