메뉴 건너뛰기




Volumn 43, Issue 6 SUPPL., 1999, Pages

Apoptosis of retinal ganglion cells in glaucoma: An update of the molecular pathways involved in cell death

Author keywords

Apoptosis; Bcl 2 related genes; Caspases; Glaucoma; Mitochondria; P53; Retinal ganglion cells

Indexed keywords

CASPASE; PROTEIN MDM2; PROTEIN P53;

EID: 0032797074     PISSN: 00396257     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0039-6257(99)00029-6     Document Type: Conference Paper
Times cited : (214)

References (94)
  • 1
    • 0032575688 scopus 로고    scopus 로고
    • The bcl-2 protein family: Arbiters of cell survival
    • Adam J.M., Cory S. The bcl-2 protein family. arbiters of cell survival Science. 281:1998;1322-1326.
    • (1998) Science , vol.281 , pp. 1322-1326
    • Adam, J.M.1    Cory, S.2
  • 2
    • 0016240481 scopus 로고
    • Effect of intraocular pressure on rapid axoplasmic transport in monkey optic nerve
    • Anderson D.R., Hendrickson A. Effect of intraocular pressure on rapid axoplasmic transport in monkey optic nerve. Invest Ophthalmol. 13:1974;771-783.
    • (1974) Invest Ophthalmol , vol.13 , pp. 771-783
    • Anderson, D.R.1    Hendrickson, A.2
  • 3
    • 9844257587 scopus 로고    scopus 로고
    • Inhibition of Bax channel-forming activity by Bcl-2
    • Antonsson B., Conti F., Ciavatta A.et al. Inhibition of Bax channel-forming activity by Bcl-2. Science. 277:1997;370-372.
    • (1997) Science , vol.277 , pp. 370-372
    • Antonsson, B.1    Conti, F.2    Ciavatta, A.3
  • 4
    • 0031587821 scopus 로고    scopus 로고
    • Recruitment of p300/CBP in p53-dependent signal pathways
    • Avantaggiati M.L., Ogryzko V., Gardner K.et al. Recruitment of p300/CBP in p53-dependent signal pathways. Cell. 89:1997;1175-1184.
    • (1997) Cell , vol.89 , pp. 1175-1184
    • Avantaggiati, M.L.1    Ogryzko, V.2    Gardner, K.3
  • 5
    • 0028310855 scopus 로고
    • Axotomy results in delayed death and apoptosis of retinal ganglion cells in adult rats
    • Berkelaar M., Clarke D.B., Wang Y.-C., Aguayo A.J. Axotomy results in delayed death and apoptosis of retinal ganglion cells in adult rats. J. Neurosci. 14:1994;4368-4374.
    • (1994) J. Neurosci , vol.14 , pp. 4368-4374
    • Berkelaar, M.1    Clarke, D.B.2    Wang, Y.-C.3    Aguayo, A.J.4
  • 6
    • 0027282044 scopus 로고
    • Bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death
    • Boise L.H., González-García M., Postema C.E.et al. bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell. 74:1993;597-608.
    • (1993) Cell , vol.74 , pp. 597-608
    • Boise, L.H.1    González-García, M.2    Postema, C.E.3
  • 7
    • 0030008918 scopus 로고    scopus 로고
    • Protection of retinal ganglion cells from natural and axotomy-induced cell death in neonatal transgenic mice overexpressing bcl-2
    • Bonfanti L., Strettoi E., Chierzi S.et al. Protection of retinal ganglion cells from natural and axotomy-induced cell death in neonatal transgenic mice overexpressing bcl-2. J Neurosci. 16:1996;4186-4194.
    • (1996) J Neurosci , vol.16 , pp. 4186-4194
    • Bonfanti, L.1    Strettoi, E.2    Chierzi, S.3
  • 8
    • 0029738162 scopus 로고    scopus 로고
    • Long-term survival of retinal ganglion cells following optic nerve section in adult bcl-2 transgenic mice
    • Cenni M.C., Bonfanti L., Martinou J.-C.et al. Long-term survival of retinal ganglion cells following optic nerve section in adult bcl-2 transgenic mice. Eur J Neurosci. 8:1996;1735-1745.
    • (1996) Eur J Neurosci , vol.8 , pp. 1735-1745
    • Cenni, M.C.1    Bonfanti, L.2    Martinou, J.-C.3
  • 9
    • 0027258466 scopus 로고
    • Thymocyte apoptosis induced by p53-dependent and independent pathways
    • Clarke A.R., Purdie C.A., Harrison D.J.et al. Thymocyte apoptosis induced by p53-dependent and independent pathways. Nature. 362:1993;849-852.
    • (1993) Nature , vol.362 , pp. 849-852
    • Clarke, A.R.1    Purdie, C.A.2    Harrison, D.J.3
  • 10
    • 0022971142 scopus 로고
    • Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation
    • Cleary M.L., Smith S.D., Sklar J. Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation. Cell. 47:1986;19-28.
    • (1986) Cell , vol.47 , pp. 19-28
    • Cleary, M.L.1    Smith, S.D.2    Sklar, J.3
  • 11
    • 0025817410 scopus 로고
    • Selective effects of experimental glaucoma on axonal transport by retinal ganglion cells to the dorsal lateral geniculate nucleus
    • Dandona L., Hendrickson A., Quigley H.A. Selective effects of experimental glaucoma on axonal transport by retinal ganglion cells to the dorsal lateral geniculate nucleus. Invest Ophthalmol Vis Sci. 32:1991;484-491.
    • (1991) Invest Ophthalmol Vis Sci , vol.32 , pp. 484-491
    • Dandona, L.1    Hendrickson, A.2    Quigley, H.A.3
  • 12
    • 0030702123 scopus 로고    scopus 로고
    • Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
    • Datta S.R., Dudek H., Tao X.et al. Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell. 91:1997;231-241.
    • (1997) Cell , vol.91 , pp. 231-241
    • Datta, S.R.1    Dudek, H.2    Tao, X.3
  • 13
    • 0028206584 scopus 로고
    • Greater sensitivity of larger retinal ganglion cells to NMDA-mediated cell death
    • Dreyer E.B., Pan Z.H., Storm S., Lipton S.A. Greater sensitivity of larger retinal ganglion cells to NMDA-mediated cell death. Neuroreport. 5:1994;629-631.
    • (1994) Neuroreport , vol.5 , pp. 629-631
    • Dreyer, E.B.1    Pan, Z.H.2    Storm, S.3    Lipton, S.A.4
  • 14
    • 0029915446 scopus 로고    scopus 로고
    • Elevated glutamate levels in the vitreous body of humans and monkeys with glaucoma
    • Dreyer E.B., Zurakowski D., Schumer R.A.et al. Elevated glutamate levels in the vitreous body of humans and monkeys with glaucoma. Arch Ophthalmol. 114:1996;299-305.
    • (1996) Arch Ophthalmol , vol.114 , pp. 299-305
    • Dreyer, E.B.1    Zurakowski, D.2    Schumer, R.A.3
  • 15
    • 0026849821 scopus 로고
    • Definition of a consensus binding site for p53
    • El-Deiry W.S., Kern S.E., Pietenpol J.A.et al. Definition of a consensus binding site for p53. Nat Genet. 1:1992;45-49.
    • (1992) Nat Genet , vol.1 , pp. 45-49
    • El-Deiry, W.S.1    Kern, S.E.2    Pietenpol, J.A.3
  • 16
    • 0027973061 scopus 로고
    • CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1β-concerting enzyme
    • Fernandez-Alnemri T., Litwack G., Alnemri E.S. CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1β-concerting enzyme. J Biol Chem. 269:1994;30761-30764.
    • (1994) J Biol Chem , vol.269 , pp. 30761-30764
    • Fernandez-Alnemri, T.1    Litwack, G.2    Alnemri, E.S.3
  • 17
    • 0030907987 scopus 로고    scopus 로고
    • PI3K: Downstream AKTion blocks apoptosis
    • Franke T.F., Kaplan D.R., Cantley L.C. PI3K. downstream AKTion blocks apoptosis Cell. 88:1997;435-437.
    • (1997) Cell , vol.88 , pp. 435-437
    • Franke, T.F.1    Kaplan, D.R.2    Cantley, L.C.3
  • 19
    • 0029069797 scopus 로고
    • Programmed cell death of retinal ganglion cells during experimental glaucoma
    • Garcia-Valenzuela E., Shareef S.et al. Programmed cell death of retinal ganglion cells during experimental glaucoma. Exp Eye Res. 61:1995;33-44.
    • (1995) Exp Eye Res , vol.61 , pp. 33-44
    • Garcia-Valenzuela, E.1    Shareef, S.2
  • 20
    • 0029868075 scopus 로고    scopus 로고
    • The p53 signal transduction pathway is intact in human neuroblastoma despite cytoplasmic localization
    • Goldman S.C., Chen C.-Y., Lansing T.J., Walsh J., Sharma S.C. The p53 signal transduction pathway is intact in human neuroblastoma despite cytoplasmic localization. Am J Pathol. 148:1996;1381-1385.
    • (1996) Am J Pathol , vol.148 , pp. 1381-1385
    • Goldman, S.C.1    Chen, C.-Y.2    Lansing, T.J.3    Walsh, J.4    Sharma, S.C.5
  • 21
    • 0029073131 scopus 로고
    • Bcl-x is expressed in embryonic and postnatal neural tissues and functions to prevent neuronal cell death
    • González-García M., García I., Ding L.et al. bcl-x is expressed in embryonic and postnatal neural tissues and functions to prevent neuronal cell death. Proc Natl Acad Sci U S A. 92:1995;4304-4308.
    • (1995) Proc Natl Acad Sci U S a , vol.92 , pp. 4304-4308
    • González-García, M.1    García, I.2    Ding, L.3
  • 22
    • 0032575752 scopus 로고    scopus 로고
    • Mitochondria and apoptosis
    • Green D.R., Reed J.C. Mitochondria and apoptosis. Science. 281:1998;1309-1312.
    • (1998) Science , vol.281 , pp. 1309-1312
    • Green, D.R.1    Reed, J.C.2
  • 23
    • 0028893492 scopus 로고
    • Superoxide dismutase delays neuronal apoptosis: A role for reactive oxygen species in programmed neuronal death
    • Greenlund L.J.S., Deckwerth T.L., Johnson J. Superoxide dismutase delays neuronal apoptosis. a role for reactive oxygen species in programmed neuronal death Neuron. 14:1995;303-315.
    • (1995) Neuron , vol.14 , pp. 303-315
    • Greenlund, L.J.S.1    Deckwerth, T.L.2    Johnson, J.3
  • 24
    • 0028230596 scopus 로고
    • Down-regulation of bcl-2 by p53 in breast cancer cells
    • Halder S., Negrini M., Monne M.et al. Down-regulation of bcl-2 by p53 in breast cancer cells. Cancer Res. 54:1994;2095-2097.
    • (1994) Cancer Res , vol.54 , pp. 2095-2097
    • Halder, S.1    Negrini, M.2    Monne, M.3
  • 25
    • 0027496935 scopus 로고
    • The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
    • Harper J.W., Adami G.R., Wei N.et al. The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell. 75:1993;805-816.
    • (1993) Cell , vol.75 , pp. 805-816
    • Harper, J.W.1    Adami, G.R.2    Wei, N.3
  • 26
    • 0028288277 scopus 로고
    • C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2
    • Hengartner M.O., Horvitz H.R. C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2. Cell. 76:1994;665-676.
    • (1994) Cell , vol.76 , pp. 665-676
    • Hengartner, M.O.1    Horvitz, H.R.2
  • 27
    • 0031310665 scopus 로고    scopus 로고
    • 14-3-3σ is p53-regulated inhibitor of G2/M progression
    • Hermeking H., Lengauer C., Polyak K.et al. 14-3-3σ is p53-regulated inhibitor of G2/M progression. Mol Cell. 1:1997;3-11.
    • (1997) Mol Cell , vol.1 , pp. 3-11
    • Hermeking, H.1    Lengauer, C.2    Polyak, K.3
  • 28
    • 0025204548 scopus 로고
    • Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
    • Hockenbery D., Nuñez G., Milliman C.et al. Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature. 348:1990;334-336.
    • (1990) Nature , vol.348 , pp. 334-336
    • Hockenbery, D.1    Nuñez, G.2    Milliman, C.3
  • 30
    • 0031007644 scopus 로고    scopus 로고
    • Nonionic detergents induce dimerization among members of the Bcl-2 family
    • Hsu Y.-T., Youle R.J. Nonionic detergents induce dimerization among members of the Bcl-2 family. J Biol Chem. 272:1997;13829-13834.
    • (1997) J Biol Chem , vol.272 , pp. 13829-13834
    • Hsu, Y.-T.1    Youle, R.J.2
  • 31
    • 0026735829 scopus 로고
    • Fragmentation of DNA in the retina of chicken embryos coincides with retinal ganglion cell death
    • Ilschner S.U., Waring P. Fragmentation of DNA in the retina of chicken embryos coincides with retinal ganglion cell death. Biochem Biophys Res Commun. 183:1992;1056-1061.
    • (1992) Biochem Biophys Res Commun , vol.183 , pp. 1056-1061
    • Ilschner, S.U.1    Waring, P.2
  • 32
    • 0030851891 scopus 로고    scopus 로고
    • Up-regulation of Bax protein in degenerating retinal ganglion cells precedes apoptotic cell death after optic nerve lesion in the rat
    • Isenmann S., Wahl C., Krajewski S.et al. Up-regulation of Bax protein in degenerating retinal ganglion cells precedes apoptotic cell death after optic nerve lesion in the rat. Eur J Neurosci. 9:1997;1763-1772.
    • (1997) Eur J Neurosci , vol.9 , pp. 1763-1772
    • Isenmann, S.1    Wahl, C.2    Krajewski, S.3
  • 33
    • 0027476151 scopus 로고
    • Bcl-2 blocks apoptosis in cells lacking mitochondria
    • Jacobson M.D., Burne J.F., King M.P.et al. Bcl-2 blocks apoptosis in cells lacking mitochondria. Nature. 361:1993;365-369.
    • (1993) Nature , vol.361 , pp. 365-369
    • Jacobson, M.D.1    Burne, J.F.2    King, M.P.3
  • 34
    • 0022519440 scopus 로고
    • Brain-derived neurotrophic factor supports the survival of cultured rat retinal ganglion cells
    • Johnson J.E., Barde Y.-A., Schwab M., Thoenen H. Brain-derived neurotrophic factor supports the survival of cultured rat retinal ganglion cells. J Neurosci. 6:1986;3031-3038.
    • (1986) J Neurosci , vol.6 , pp. 3031-3038
    • Johnson, J.E.1    Barde, Y.-A.2    Schwab, M.3    Thoenen, H.4
  • 35
    • 0032574761 scopus 로고    scopus 로고
    • Bax directly induces release of cytochrome c from isolated mitochondria
    • Jurgensmeier J.M., Xie Z.H., Deveraux Q.et al. Bax directly induces release of cytochrome c from isolated mitochondria. Proc Natl Acad Sci U S A. 95:1998;4997-5002.
    • (1998) Proc Natl Acad Sci U S a , vol.95 , pp. 4997-5002
    • Jurgensmeier, J.M.1    Xie, Z.H.2    Deveraux, Q.3
  • 36
    • 0027717968 scopus 로고
    • Bcl-2 inhibition of neural death: Decreased generation of reactive oxygen species
    • Kane D.J., Sarafian T.A., Anton R.et al. Bcl-2 inhibition of neural death. decreased generation of reactive oxygen species Science. 262:1993;1274-1277.
    • (1993) Science , vol.262 , pp. 1274-1277
    • Kane, D.J.1    Sarafian, T.A.2    Anton, R.3
  • 37
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr J.F.R., Wyllie A.H., Currie A.R. Apoptosis. a basic biological phenomenon with wide-ranging implications in tissue kinetics Br J Cancer. 26:1972;239-257.
    • (1972) Br J Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.R.1    Wyllie, A.H.2    Currie, A.R.3
  • 38
    • 0030755980 scopus 로고    scopus 로고
    • TUNEL-positive ganglion cells in human primary open-angle glaucoma
    • Kerrigan L.A., Zack D.J., Quigley H.A.et al. TUNEL-positive ganglion cells in human primary open-angle glaucoma. Arch Ophthalmol. 115:1997;1031-1035.
    • (1997) Arch Ophthalmol , vol.115 , pp. 1031-1035
    • Kerrigan, L.A.1    Zack, D.J.2    Quigley, H.A.3
  • 39
    • 0030861571 scopus 로고    scopus 로고
    • Bcl-2 and Bax function independently to regulate cell death
    • Knudson C.M., Korsmeyer S.J. Bcl-2 and Bax function independently to regulate cell death. Nat Genet. 16:1997;358-363.
    • (1997) Nat Genet , vol.16 , pp. 358-363
    • Knudson, C.M.1    Korsmeyer, S.J.2
  • 40
    • 0031563764 scopus 로고    scopus 로고
    • Involvement of p53 and waf1/cip1 in gamma-irradiation-induced apoptosis of retinoblastoma cells
    • Kondo Y., Kondo S., Liu J.B.et al. Involvement of p53 and waf1/cip1 in gamma-irradiation-induced apoptosis of retinoblastoma cells. Exp Cell Res. 236:1997;51-56.
    • (1997) Exp Cell Res , vol.236 , pp. 51-56
    • Kondo, Y.1    Kondo, S.2    Liu, J.B.3
  • 41
    • 0029870073 scopus 로고    scopus 로고
    • Apoptosis of retinal ganglion cells in anterior ischemic optic neuropathy
    • Levin L.A., Louhab A. Apoptosis of retinal ganglion cells in anterior ischemic optic neuropathy. Arch Ophthalmol. 114:1996;488-491.
    • (1996) Arch Ophthalmol , vol.114 , pp. 488-491
    • Levin, L.A.1    Louhab, A.2
  • 43
    • 0030941458 scopus 로고    scopus 로고
    • P53, the cellular gatekeeper for growth and division
    • Levine A.J. p53, the cellular gatekeeper for growth and division. Cell. 88:1997;323-332.
    • (1997) Cell , vol.88 , pp. 323-332
    • Levine, A.J.1
  • 44
    • 0030715323 scopus 로고    scopus 로고
    • Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
    • Li P., Nijhawan D., Budihardjo I.et al. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell. 91:1997;479-489.
    • (1997) Cell , vol.91 , pp. 479-489
    • Li, P.1    Nijhawan, D.2    Budihardjo, I.3
  • 45
    • 0344234081 scopus 로고    scopus 로고
    • The role of p53 in retinal ganglion cell death in mice
    • Li Y., Schlamp C.L., Jackson M.W.et al. The role of p53 in retinal ganglion cell death in mice. Invest Ophthalmol Vis Sci. 39:1998;S261.
    • (1998) Invest Ophthalmol Vis Sci , vol.39 , pp. 261
    • Li, Y.1    Schlamp, C.L.2    Jackson, M.W.3
  • 46
    • 0033026589 scopus 로고    scopus 로고
    • Experimental induction of ganglion cell death in adult mice
    • Li Y., Schlamp C.L., Nickells R.W. Experimental induction of ganglion cell death in adult mice. Invest Ophthalmol Vis Sci. 40:1999;1004-1008.
    • (1999) Invest Ophthalmol Vis Sci , vol.40 , pp. 1004-1008
    • Li, Y.1    Schlamp, C.L.2    Nickells, R.W.3
  • 47
    • 0028762647 scopus 로고
    • Excitatory amino acids as a final common pathway for neurologic disorders
    • Lipton S.A., Rosenberg P.A. Excitatory amino acids as a final common pathway for neurologic disorders. N Engl J Med. 330:1994;613-622.
    • (1994) N Engl J Med , vol.330 , pp. 613-622
    • Lipton, S.A.1    Rosenberg, P.A.2
  • 48
    • 0030581151 scopus 로고    scopus 로고
    • Induction of apoptotic program in cell-free extracts: Requirements for dATP and cytochrome c
    • Lui X., Kim C.N., Yang J.et al. Induction of apoptotic program in cell-free extracts. requirements for dATP and cytochrome c Cell. 86:1996;147-157.
    • (1996) Cell , vol.86 , pp. 147-157
    • Lui, X.1    Kim, C.N.2    Yang, J.3
  • 50
    • 0028324822 scopus 로고
    • Effects of ocular injury and administration of brain-derived neurotrophic factor on survival and regrowth of axotomized retinal ganglion cells
    • Mansour-Robaey S., Clarke D.B., Wang Y.-C.et al. Effects of ocular injury and administration of brain-derived neurotrophic factor on survival and regrowth of axotomized retinal ganglion cells. Proc Natl Acad Sci U S A. 91:1994;1632-1636.
    • (1994) Proc Natl Acad Sci U S a , vol.91 , pp. 1632-1636
    • Mansour-Robaey, S.1    Clarke, D.B.2    Wang, Y.-C.3
  • 51
    • 9544246860 scopus 로고    scopus 로고
    • Mitochondrial permeability transition is a central coordinating event of apoptosis
    • Marchetti P., Castedo M., Susin S.A.et al. Mitochondrial permeability transition is a central coordinating event of apoptosis. J Exp Med. 184:1996;1155-1160.
    • (1996) J Exp Med , vol.184 , pp. 1155-1160
    • Marchetti, P.1    Castedo, M.2    Susin, S.A.3
  • 52
    • 0027944004 scopus 로고
    • Overexpression of BCL-1 in transgenic mice protects neurons from naturally occurring cell death an experimental ischemia
    • Martinou J.-C., Dubois-Dauphin M., Staple J.K.et al. Overexpression of BCL-1 in transgenic mice protects neurons from naturally occurring cell death an experimental ischemia. Neuron. 13:1994;1017-1030.
    • (1994) Neuron , vol.13 , pp. 1017-1030
    • Martinou, J.-C.1    Dubois-Dauphin, M.2    Staple, J.K.3
  • 53
    • 0032566649 scopus 로고    scopus 로고
    • Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis
    • Marzo I., Brenner C., Zamzami N.et al. Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis. Science. 281:1998;2027-2031.
    • (1998) Science , vol.281 , pp. 2027-2031
    • Marzo, I.1    Brenner, C.2    Zamzami, N.3
  • 54
    • 0032550363 scopus 로고    scopus 로고
    • The permeability transition pore complex: A target for apoptosis regulation by caspases and bcl-2-related proteins
    • Marzo I., Brenner C., Zamzami N.et al. The permeability transition pore complex. a target for apoptosis regulation by caspases and bcl-2-related proteins J Exp Med. 187:1998;1261-1271.
    • (1998) J Exp Med , vol.187 , pp. 1261-1271
    • Marzo, I.1    Brenner, C.2    Zamzami, N.3
  • 55
    • 1842332735 scopus 로고    scopus 로고
    • L forms an ion channel in synthetic lipid membranes
    • L forms an ion channel in synthetic lipid membranes. Nature. 385:1997;353-357.
    • (1997) Nature , vol.385 , pp. 353-357
    • Minn, A.J.1    Velez, P.2    Schendel, S.L.3
  • 56
    • 0028292480 scopus 로고
    • Identification of a p53-dependent negative response element in the bcl-2 gene
    • Miyashita T., Harigai M., Hanada M., Reed J.C. Identification of a p53-dependent negative response element in the bcl-2 gene. Cancer Res. 54:1994;3131-3135.
    • (1994) Cancer Res , vol.54 , pp. 3131-3135
    • Miyashita, T.1    Harigai, M.2    Hanada, M.3    Reed, J.C.4
  • 57
    • 0028883179 scopus 로고
    • Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
    • Miyashita T., Reed J.C. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell. 80:1995;293-299.
    • (1995) Cell , vol.80 , pp. 293-299
    • Miyashita, T.1    Reed, J.C.2
  • 58
    • 0031828871 scopus 로고    scopus 로고
    • Suppression of developmental retinal cell death but not photoreceptor degeneration in Bax-deficient mice
    • Mosinger Oglivie J., Deckwerth T.L., Knudson C.M., Korsmeyer S.J. Suppression of developmental retinal cell death but not photoreceptor degeneration in Bax-deficient mice. Invest Ophthalmol Vis Sci. 39:1998;1713-1720.
    • (1998) Invest Ophthalmol Vis Sci , vol.39 , pp. 1713-1720
    • Mosinger Oglivie, J.1    Deckwerth, T.L.2    Knudson, C.M.3    Korsmeyer, S.J.4
  • 60
    • 0029908754 scopus 로고    scopus 로고
    • Retinal ganglion cell death in glaucoma: The how, the why, and the maybe
    • Nickells R.W. Retinal ganglion cell death in glaucoma. the how, the why, and the maybe J Glaucoma. 5:1996;345-356.
    • (1996) J Glaucoma , vol.5 , pp. 345-356
    • Nickells, R.W.1
  • 61
    • 0030446479 scopus 로고    scopus 로고
    • Apoptosis in ocular disease: A molecular overview
    • Nickells R.W., Zack D.J. Apoptosis in ocular disease. A molecular overview Ophthalmic Genet. 17:1996;145-165.
    • (1996) Ophthalmic Genet , vol.17 , pp. 145-165
    • Nickells, R.W.1    Zack, D.J.2
  • 62
    • 0031044873 scopus 로고    scopus 로고
    • P53 regulates apoptosis in human retinoblastoma
    • Nork T.M., Poulsen G., Millecchia L.L.et al. p53 regulates apoptosis in human retinoblastoma. Arch Ophthalmol. 115:1997;213-219.
    • (1997) Arch Ophthalmol , vol.115 , pp. 213-219
    • Nork, T.M.1    Poulsen, G.2    Millecchia, L.L.3
  • 63
    • 0020263571 scopus 로고
    • The toxic effects of glutamate and related compounds in the retina and the brain
    • Olney J.W. The toxic effects of glutamate and related compounds in the retina and the brain. Retina. 2:1982;341-359.
    • (1982) Retina , vol.2 , pp. 341-359
    • Olney, J.W.1
  • 64
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homology, Bax, that accelerates programmed cell death
    • Oltvai Z., Milliman C., Korsmeyer S.J. Bcl-2 heterodimerizes in vivo with a conserved homology, Bax, that accelerates programmed cell death. Cell. 74:1993;609-619.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.1    Milliman, C.2    Korsmeyer, S.J.3
  • 65
    • 0026058318 scopus 로고
    • Cell death during development of the nervous system
    • Oppenheim R.W. Cell death during development of the nervous system. Ann Rev Neurosci. 14:1991;453-501.
    • (1991) Ann Rev Neurosci , vol.14 , pp. 453-501
    • Oppenheim, R.W.1
  • 66
    • 0029093605 scopus 로고
    • Temporally distinct patterns of p53-dependent and p53-independent apoptosis during mouse lens development
    • Pan H., Griep A.E. Temporally distinct patterns of p53-dependent and p53-independent apoptosis during mouse lens development. Genes Dev. 9:1995;2157-2169.
    • (1995) Genes Dev , vol.9 , pp. 2157-2169
    • Pan, H.1    Griep, A.E.2
  • 67
    • 0019523221 scopus 로고
    • Optic nerve damage in human glaucoma: II. The site of injury and susceptibility to damage
    • Quigley H.A., Addicks E.M., Green W.R., Maumenee A.E. Optic nerve damage in human glaucoma. II. The site of injury and susceptibility to damage Arch Ophthalmol. 99:1981;635-649.
    • (1981) Arch Ophthalmol , vol.99 , pp. 635-649
    • Quigley, H.A.1    Addicks, E.M.2    Green, W.R.3    Maumenee, A.E.4
  • 68
    • 0028907952 scopus 로고
    • Retinal ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosis
    • Quigley H.A., Nickells R.W., Kerrigan L.A.et al. Retinal ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosis. Invest Ophthalmol Vis Sci. 36:1995;774-786.
    • (1995) Invest Ophthalmol Vis Sci , vol.36 , pp. 774-786
    • Quigley, H.A.1    Nickells, R.W.2    Kerrigan, L.A.3
  • 69
    • 0019513111 scopus 로고
    • Rapid axonal transport in primate optic nerve
    • Radius R.L., Anderson D.R. Rapid axonal transport in primate optic nerve. Arch Opthalmol. 99:1981;650-654.
    • (1981) Arch Opthalmol , vol.99 , pp. 650-654
    • Radius, R.L.1    Anderson, D.R.2
  • 70
    • 0030782177 scopus 로고    scopus 로고
    • Cytochrome c: Can't live with it - Can't live without it
    • Reed J.C. Cytochrome c. can't live with it - can't live without it Cell. 91:1997;559-562.
    • (1997) Cell , vol.91 , pp. 559-562
    • Reed, J.C.1
  • 71
    • 0031708027 scopus 로고    scopus 로고
    • The role of the p53 protein in the selective vulnerability of the inner retina to transient ischemia
    • Rosenbaum D.M., Rosenbaum P.S., Gupta H.et al. The role of the p53 protein in the selective vulnerability of the inner retina to transient ischemia. Invest Ophthalmol Vis Sci. 39:1998;2132-2139.
    • (1998) Invest Ophthalmol Vis Sci , vol.39 , pp. 2132-2139
    • Rosenbaum, D.M.1    Rosenbaum, P.S.2    Gupta, H.3
  • 72
    • 17644434288 scopus 로고    scopus 로고
    • Induction of tumor supressor p53 and DNA fragmentation in organotypic hippocampal cultures following excitotoxin treatment
    • Sakhi S., Bruce A., Sun N.et al. Induction of tumor supressor p53 and DNA fragmentation in organotypic hippocampal cultures following excitotoxin treatment. Exp Neurol. 145:1997;81-88.
    • (1997) Exp Neurol , vol.145 , pp. 81-88
    • Sakhi, S.1    Bruce, A.2    Sun, N.3
  • 73
    • 0030702084 scopus 로고    scopus 로고
    • Caspases: Intracellular signaling by proteolysis
    • Salvesen G.S., Dixit V.M. Caspases. intracellular signaling by proteolysis Cell. 91:1997;443-446.
    • (1997) Cell , vol.91 , pp. 443-446
    • Salvesen, G.S.1    Dixit, V.M.2
  • 74
    • 0030779846 scopus 로고    scopus 로고
    • Comparison of the ion channel characteristics of proapoptotic Bax and antiapoptotic Bcl-2
    • Schlesinger P.H., Gross A., Yin X.M.et al. Comparison of the ion channel characteristics of proapoptotic Bax and antiapoptotic Bcl-2. Proc Natl Acad Sci U S A. 94:1997;11357-11362.
    • (1997) Proc Natl Acad Sci U S a , vol.94 , pp. 11357-11362
    • Schlesinger, P.H.1    Gross, A.2    Yin, X.M.3
  • 75
    • 0026793456 scopus 로고
    • Growth factor signaling by receptor tyrosine kinases
    • Schlessinger J., Ullrich A. Growth factor signaling by receptor tyrosine kinases. Neuron. 9:1992;383-391.
    • (1992) Neuron , vol.9 , pp. 383-391
    • Schlessinger, J.1    Ullrich, A.2
  • 76
    • 0030667702 scopus 로고    scopus 로고
    • DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
    • Shieh S.-Y., Ikeda M., Taya Y., Prives C. DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2. Cell. 91:1997;325-334.
    • (1997) Cell , vol.91 , pp. 325-334
    • Shieh, S.-Y.1    Ikeda, M.2    Taya, Y.3    Prives, C.4
  • 78
    • 0026873352 scopus 로고
    • N-methyl-D-aspartate-induced neurotoxicity in the adult rat retina
    • Siliprandi R., Canella R., Carmignoto G.et al. N-methyl-D-aspartate-induced neurotoxicity in the adult rat retina. Vis Neurosci. 8:1992;567-573.
    • (1992) Vis Neurosci , vol.8 , pp. 567-573
    • Siliprandi, R.1    Canella, R.2    Carmignoto, G.3
  • 79
    • 0028847915 scopus 로고
    • Cloning and functional analysis of BAG-1: A novel Bcl-2-binding protein with anti-cell death activity
    • Takayama S., Sato T., Krajewski S.et al. Cloning and functional analysis of BAG-1. a novel Bcl-2-binding protein with anti-cell death activity Cell. 80:1995;279-284.
    • (1995) Cell , vol.80 , pp. 279-284
    • Takayama, S.1    Sato, T.2    Krajewski, S.3
  • 80
    • 0028990125 scopus 로고
    • Yama/Cpp32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
    • Tewari M., Quan L.T., O'Rourke K.et al. Yama/Cpp32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell. 81:1995;801-809.
    • (1995) Cell , vol.81 , pp. 801-809
    • Tewari, M.1    Quan, L.T.2    O'Rourke, K.3
  • 81
    • 0030613796 scopus 로고    scopus 로고
    • L regulates the membrane potential and volume homeostasis of mitochondria
    • L regulates the membrane potential and volume homeostasis of mitochondria. Cell. 91:1997;627-637.
    • (1997) Cell , vol.91 , pp. 627-637
    • Vander Heiden, M.G.1    Chandel, N.S.2    Williamson, E.K.3
  • 82
    • 0027050145 scopus 로고
    • Prevention of programmed cell death in Caenorhaditis elegans by human bcl-2
    • Vaux D.L., Weissman I.L., Kim S.K. Prevention of programmed cell death in Caenorhaditis elegans by human bcl-2. Science. 258:1992;1955-1957.
    • (1992) Science , vol.258 , pp. 1955-1957
    • Vaux, D.L.1    Weissman, I.L.2    Kim, S.K.3
  • 83
    • 0029778159 scopus 로고    scopus 로고
    • Chronic low-dose glutamate is toxic to retinal ganglion cells: Toxicity blocked by memantine
    • Vorwerk C.K., Lipton S.A., Zurakowski D.et al. Chronic low-dose glutamate is toxic to retinal ganglion cells. Toxicity blocked by memantine Invest Ophthalmol Vis Sci. 37:1996;1618-1624.
    • (1996) Invest Ophthalmol Vis Sci , vol.37 , pp. 1618-1624
    • Vorwerk, C.K.1    Lipton, S.A.2    Zurakowski, D.3
  • 84
    • 0030780106 scopus 로고    scopus 로고
    • Movement of bax from the cytosol to mitochondria during apoptosis
    • Wolter K.G., Hsu Y.T., Smith C.L.et al. Movement of bax from the cytosol to mitochondria during apoptosis. J Cell Biol. 139:1997;1281-1292.
    • (1997) J Cell Biol , vol.139 , pp. 1281-1292
    • Wolter, K.G.1    Hsu, Y.T.2    Smith, C.L.3
  • 85
    • 0032519859 scopus 로고    scopus 로고
    • Bax involvement in p53-mediated cell death
    • Xiang H., Kinoshital Y., Knudson C.M.et al. Bax involvement in p53-mediated cell death. J Neurosci. 18:1998;1363-1373.
    • (1998) J Neurosci , vol.18 , pp. 1363-1373
    • Xiang, H.1    Kinoshital, Y.2    Knudson, C.M.3
  • 86
    • 0029906828 scopus 로고    scopus 로고
    • BAX-induced cell death may not require interleukin-1-beta converting enzyme-like proteases
    • Xiang J., Chao D.T., Korsmeyer S.J. BAX-induced cell death may not require interleukin-1-beta converting enzyme-like proteases. Proc Natl Acad Sci U S A. 93:1996;14559-14563.
    • (1996) Proc Natl Acad Sci U S a , vol.93 , pp. 14559-14563
    • Xiang, J.1    Chao, D.T.2    Korsmeyer, S.J.3
  • 87
    • 0027717617 scopus 로고
    • P21 is a universal inhibitor of cyclin kinases
    • Xiong Y., Hannon G.J., Zhang H.et al. p21 is a universal inhibitor of cyclin kinases. Nature. 366:1993;701-704.
    • (1993) Nature , vol.366 , pp. 701-704
    • Xiong, Y.1    Hannon, G.J.2    Zhang, H.3
  • 88
    • 0028809209 scopus 로고
    • L and Bcl-2, displaces Bax and promotes cell death
    • L and Bcl-2, displaces Bax and promotes cell death. Cell. 80:1995;285-291.
    • (1995) Cell , vol.80 , pp. 285-291
    • Yang, E.1    Zha, J.2    Jockel, J.3
  • 89
    • 0032575723 scopus 로고    scopus 로고
    • Essential role of CED-4 oligomerization in CED-3 activation and apoptosis
    • Yang X., Chang H.Y., Baltimore D. Essential role of CED-4 oligomerization in CED-3 activation and apoptosis. Science. 281:1998;1355-1357.
    • (1998) Science , vol.281 , pp. 1355-1357
    • Yang, X.1    Chang, H.Y.2    Baltimore, D.3
  • 90
    • 0028206341 scopus 로고
    • BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax
    • Yin X.-M., Oltvai Z.N., Korsmeyer S.J. BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax. Nature. 369:1994;321-323.
    • (1994) Nature , vol.369 , pp. 321-323
    • Yin, X.-M.1    Oltvai, Z.N.2    Korsmeyer, S.J.3
  • 91
    • 0030866842 scopus 로고    scopus 로고
    • NMDA-receptor antagonist protects neurons from secondary degeneration after partial optic nerve crush
    • Yoles E., Muller S., Schwartz M. NMDA-receptor antagonist protects neurons from secondary degeneration after partial optic nerve crush. J Neurotrauma. 14:1997;665-675.
    • (1997) J Neurotrauma , vol.14 , pp. 665-675
    • Yoles, E.1    Muller, S.2    Schwartz, M.3
  • 92
    • 0027525104 scopus 로고
    • The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme
    • Yuan J., Shaham S., Ledoux S.et al. The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme. Cell. 75:1993;641-652.
    • (1993) Cell , vol.75 , pp. 641-652
    • Yuan, J.1    Shaham, S.2    Ledoux, S.3
  • 93
    • 0032567877 scopus 로고    scopus 로고
    • The thiol crosslinking agent diamide overcomes the apoptosis-inhibitory effect of bcl-2 by enforcing mitochondrial permeability transition
    • Zamzami N., Marzo I., Susin S.A.et al. The thiol crosslinking agent diamide overcomes the apoptosis-inhibitory effect of bcl-2 by enforcing mitochondrial permeability transition. Oncogene. 16:1998;1055-1063.
    • (1998) Oncogene , vol.16 , pp. 1055-1063
    • Zamzami, N.1    Marzo, I.2    Susin, S.A.3
  • 94
    • 0030745646 scopus 로고    scopus 로고
    • Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3
    • Zou H., Henzel W.J., Liu X.et al. Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell. 90:1997;405-413.
    • (1997) Cell , vol.90 , pp. 405-413
    • Zou, H.1    Henzel, W.J.2    Liu, X.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.