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Volumn 66, Issue 2, 2006, Pages 153-176

Mitochondrial DNA in pathogenesis of Alzheimer's and Parkinson's diseases

Author keywords

Alzheimer's disease; Haplogroups; Mitochondrial DNA; Neurodegeneration; Parkinson's disease; Single nucleotide polymorphisms

Indexed keywords

CELL NUCLEUS DNA; MITOCHONDRIAL DNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE);

EID: 33746464382     PISSN: 00651400     EISSN: 00651400     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (24)

References (164)
  • 1
    • 33644543761 scopus 로고    scopus 로고
    • Expanding insights of mitochondrial dysfunction in Parkinson's disease
    • Abou-Sleiman PM, Muqit MM, Wood NW (2006) Expanding insights of mitochondrial dysfunction in Parkinson's disease. Nat Rev Neurosci 7: 207-219.
    • (2006) Nat Rev Neurosci , vol.7 , pp. 207-219
    • Abou-Sleiman, P.M.1    Muqit, M.M.2    Wood, N.W.3
  • 2
    • 0030878073 scopus 로고    scopus 로고
    • Oxidative DNA damage in the parkinsonian brain: An apparent selective increase in 8-hydroxyguanine levels in substantia nigra
    • Alam ZI, Jenner A, Daniel SE, Lees AJ, Cairns N, Marsden CD, Jenner P, Halliwell B (1997) Oxidative DNA damage in the parkinsonian brain: an apparent selective increase in 8-hydroxyguanine levels in substantia nigra. J Neurochem 69: 1196-1203.
    • (1997) J Neurochem , vol.69 , pp. 1196-1203
    • Alam, Z.I.1    Jenner, A.2    Daniel, S.E.3    Lees, A.J.4    Cairns, N.5    Marsden, C.D.6    Jenner, P.7    Halliwell, B.8
  • 3
    • 26444588771 scopus 로고    scopus 로고
    • Gradual alteration of mitochondrial structure and function by beta-amyloids: Importance of membrane viscosity changes, energy deprivation, reactive oxygen species production, and cytochrome c release
    • Aleardi AM, Benard G, Augereau O, Malgat M, Talbot JC, Mazat JP, Letellier T, Dachary-Prigent J, Solaini GC, Rossignol R (2005) Gradual alteration of mitochondrial structure and function by beta-amyloids: Importance of membrane viscosity changes, energy deprivation, reactive oxygen species production, and cytochrome c release. J Bioenerg Biomembr 37: 207-225.
    • (2005) J Bioenerg Biomembr , vol.37 , pp. 207-225
    • Aleardi, A.M.1    Benard, G.2    Augereau, O.3    Malgat, M.4    Talbot, J.C.5    Mazat, J.P.6    Letellier, T.7    Dachary-Prigent, J.8    Solaini, G.C.9    Rossignol, R.10
  • 4
    • 0036847136 scopus 로고    scopus 로고
    • Characterization of the Caucasian haplogroups present in the SWGDAM forensic mtDNA dataset for 1771 human control region sequences
    • Scientific Working Group on DNA Analysis Methods
    • Allard MW, Miller K, Wilson M, Monson K, Budowle B (2002) Characterization of the Caucasian haplogroups present in the SWGDAM forensic mtDNA dataset for 1771 human control region sequences. Scientific Working Group on DNA Analysis Methods. J Forensic Sci 47: 1215-1223.
    • (2002) J Forensic Sci , vol.47 , pp. 1215-1223
    • Allard, M.W.1    Miller, K.2    Wilson, M.3    Monson, K.4    Budowle, B.5
  • 5
    • 0037437192 scopus 로고    scopus 로고
    • Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells
    • Anandatheerthavarada HK, Biswas G, Robin MA, Avadhani NG (2003) Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells. J Cell Biol 161:41-54.
    • (2003) J Cell Biol , vol.161 , pp. 41-54
    • Anandatheerthavarada, H.K.1    Biswas, G.2    Robin, M.A.3    Avadhani, N.G.4
  • 6
    • 0036965466 scopus 로고    scopus 로고
    • Endogenous risk factors in Parkinson's disease: Dopamine and tetrahydroisoquinolines
    • Antkiewicz-Michaluk L (2002) Endogenous risk factors in Parkinson's disease: dopamine and tetrahydroisoquinolines. Pol J Pharmacol 54: 567-572.
    • (2002) Pol J Pharmacol , vol.54 , pp. 567-572
    • Antkiewicz-Michaluk, L.1
  • 9
    • 0030915207 scopus 로고    scopus 로고
    • Mitochondrial DNA polymorphisms in pathologically proven Parkinson's disease
    • Bandmann O, Sweeney MG, Daniel SE, Marsden CD, Wood NW (1997) Mitochondrial DNA polymorphisms in pathologically proven Parkinson's disease. J Neurol 244: 262-265.
    • (1997) J Neurol , vol.244 , pp. 262-265
    • Bandmann, O.1    Sweeney, M.G.2    Daniel, S.E.3    Marsden, C.D.4    Wood, N.W.5
  • 10
    • 0032504710 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in neurodegenerative diseases
    • Beal MF (1998) Mitochondrial dysfunction in neurodegenerative diseases. Biochim Biophys Acta 1366: 211-223.
    • (1998) Biochim Biophys Acta , vol.1366 , pp. 211-223
    • Beal, M.F.1
  • 11
    • 0037098866 scopus 로고    scopus 로고
    • Antioxidant neuroprotection in Alzheimer's disease as preventive and therapeutic approach
    • Behl C, Moosmann B (2002) Antioxidant neuroprotection in Alzheimer's disease as preventive and therapeutic approach. Free Radic Biol Med 33: 182-191.
    • (2002) Free Radic Biol Med , vol.33 , pp. 182-191
    • Behl, C.1    Moosmann, B.2
  • 13
    • 0035906328 scopus 로고    scopus 로고
    • Mitochondrial DNA in aging and degenerative disease
    • Berdanier CD, Everts HB (2001) Mitochondrial DNA in aging and degenerative disease. Mutat Res 475: 169-183.
    • (2001) Mutat Res , vol.475 , pp. 169-183
    • Berdanier, C.D.1    Everts, H.B.2
  • 23
    • 0036745084 scopus 로고    scopus 로고
    • Does mitochondrial respiratory chain dysfunction have a role in common neurodegenerative disorders?
    • Byrne E (2002) Does mitochondrial respiratory chain dysfunction have a role in common neurodegenerative disorders? J Clin Neurosci 9: 497-501.
    • (2002) J Clin Neurosci , vol.9 , pp. 497-501
    • Byrne, E.1
  • 24
    • 24744442376 scopus 로고    scopus 로고
    • Mitochondrial DNA G10398A polymorphism and invasive breast cancer in African-American women
    • Canter JA, Kallianpur AR, Parl FF, Millikan RC (2005) Mitochondrial DNA G10398A polymorphism and invasive breast cancer in African-American women. Cancer Res 65: 8028-8033.
    • (2005) Cancer Res , vol.65 , pp. 8028-8033
    • Canter, J.A.1    Kallianpur, A.R.2    Parl, F.F.3    Millikan, R.C.4
  • 28
    • 0036272650 scopus 로고    scopus 로고
    • Beta-amyloid inhibits integrated mitochondrial respiration and key enzyme activities
    • Casley CS, Canevari L, Land JM, Clark JB, Sharpe MA (2002) Beta-amyloid inhibits integrated mitochondrial respiration and key enzyme activities. J Neurochem 80: 91-100.
    • (2002) J Neurochem , vol.80 , pp. 91-100
    • Casley, C.S.1    Canevari, L.2    Land, J.M.3    Clark, J.B.4    Sharpe, M.A.5
  • 32
    • 0034025849 scopus 로고    scopus 로고
    • The biology of mitochondrial disease
    • Clarke A (2000) The biology of mitochondrial disease. Arch Dis Child 82: 339-340.
    • (2000) Arch Dis Child , vol.82 , pp. 339-340
    • Clarke, A.1
  • 33
    • 0030803457 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in neurodegeneration
    • Cooper JM, Schapira AH (1997) Mitochondrial dysfunction in neurodegeneration. J Bioenerg Biomembr 29: 175-183.
    • (1997) J Bioenerg Biomembr , vol.29 , pp. 175-183
    • Cooper, J.M.1    Schapira, A.H.2
  • 34
    • 0037418174 scopus 로고    scopus 로고
    • Control region mtDNA variants: Longevity, climatic adaptation, and a forensic conundrum
    • U S A
    • Coskun PE, Ruiz-Pesini E, Wallace DC (2003) Control region mtDNA variants: Longevity, climatic adaptation, and a forensic conundrum. Proc Natl Acad Sci U S A 100: 2174-2176.
    • (2003) Proc Natl Acad Sci , vol.100 , pp. 2174-2176
    • Coskun, P.E.1    Ruiz-Pesini, E.2    Wallace, D.C.3
  • 35
    • 3242668604 scopus 로고    scopus 로고
    • Alzheimer's brains harbor somatic mtDNA control-region mutations that suppress mitochondrial transcription and replication
    • U S A
    • Coskun PE, Beal MF, Wallace DC (2004) Alzheimer's brains harbor somatic mtDNA control-region mutations that suppress mitochondrial transcription and replication. Proc Natl Acad Sci U S A 101: 10726-10731.
    • (2004) Proc Natl Acad Sci , vol.101 , pp. 10726-10731
    • Coskun, P.E.1    Beal, M.F.2    Wallace, D.C.3
  • 38
    • 0242363670 scopus 로고    scopus 로고
    • Molecular pathways of neurodegeneration in Parkinson's disease
    • Dawson TM, Dawson VL (2003) Molecular pathways of neurodegeneration in Parkinson's disease. Science 302: 819-822.
    • (2003) Science , vol.302 , pp. 819-822
    • Dawson, T.M.1    Dawson, V.L.2
  • 41
    • 33746395788 scopus 로고    scopus 로고
    • Dopamine: Not just a neurotransmitter
    • Drozak J, Bryla J (2005) Dopamine: not just a neurotransmitter (in Polish). Postepy Hig Med Dosw 59: 405-420.
    • (2005) Postepy Hig Med Dosw , vol.59 , pp. 405-420
    • Drozak, J.1    Bryla, J.2
  • 42
    • 4043086952 scopus 로고    scopus 로고
    • Mitochondria in health and disease: Perspectives on a new mitochondrial biology
    • Duchen MR (2004) Mitochondria in health and disease: perspectives on a new mitochondrial biology. Mol Aspects Med 25: 365-451.
    • (2004) Mol Aspects Med , vol.25 , pp. 365-451
    • Duchen, M.R.1
  • 46
    • 1642483509 scopus 로고    scopus 로고
    • Neurodegenerative diseases and oxidative stress
    • Emerit J, Edeas M, Bricaire F (2004) Neurodegenerative diseases and oxidative stress. Biomed Pharmacother 58: 39-46.
    • (2004) Biomed Pharmacother , vol.58 , pp. 39-46
    • Emerit, J.1    Edeas, M.2    Bricaire, F.3
  • 47
    • 0142121353 scopus 로고    scopus 로고
    • The contribution of mitochondria to common disorders
    • Enns GM (2003) The contribution of mitochondria to common disorders. Mol Genet Metab 80: 11-26.
    • (2003) Mol Genet Metab , vol.80 , pp. 11-26
    • Enns, G.M.1
  • 49
    • 33645116252 scopus 로고    scopus 로고
    • Genetics of Parkinson disease: Paradigm shifts and future prospects
    • Farrer MJ (2006) Genetics of Parkinson disease: paradigm shifts and future prospects. Nat Rev Genet 7: 306-318.
    • (2006) Nat Rev Genet , vol.7 , pp. 306-318
    • Farrer, M.J.1
  • 50
    • 0035081109 scopus 로고    scopus 로고
    • Phylogenetic analysis of mtDNA haplogroup TJ in a Finnish population
    • Finnila S, Majamaa K (2001) Phylogenetic analysis of mtDNA haplogroup TJ in a Finnish population. J Hum Genet 46: 64-69.
    • (2001) J Hum Genet , vol.46 , pp. 64-69
    • Finnila, S.1    Majamaa, K.2
  • 52
    • 3342978711 scopus 로고
    • Enzyme histochemical studies of senile plaques
    • Friede RI (1965) Enzyme histochemical studies of senile plaques. J Neuropathol Exp Neurol 24: 477-491.
    • (1965) J Neuropathol Exp Neurol , vol.24 , pp. 477-491
    • Friede, R.I.1
  • 53
    • 0037417220 scopus 로고    scopus 로고
    • Apoptosis and caspases in neurodegenerative diseases
    • Friedlander RM (2003) Apoptosis and caspases in neurodegenerative diseases. N Engl J Med 348: 1365-1375.
    • (2003) N Engl J Med , vol.348 , pp. 1365-1375
    • Friedlander, R.M.1
  • 58
    • 0037096193 scopus 로고    scopus 로고
    • The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer's and Parkinson's diseases
    • Giasson BI, Ischiropoulos H, Lee VM, Trojanowski JQ (2002) The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer's and Parkinson's diseases. Free Radic Biol Med 32: 1264-1275.
    • (2002) Free Radic Biol Med , vol.32 , pp. 1264-1275
    • Giasson, B.I.1    Ischiropoulos, H.2    Lee, V.M.3    Trojanowski, J.Q.4
  • 59
    • 0031737226 scopus 로고    scopus 로고
    • Abnormalities of mitochondrial enzymes in Alzheimer disease
    • Gibson GE, Sheu KF, Blass JP (1998) Abnormalities of mitochondrial enzymes in Alzheimer disease. J Neural Transm 105: 855-870.
    • (1998) J Neural Transm , vol.105 , pp. 855-870
    • Gibson, G.E.1    Sheu, K.F.2    Blass, J.P.3
  • 60
    • 2442636348 scopus 로고    scopus 로고
    • Biomedicine. Parkinson's - Divergent causes, convergent mechanisms
    • Greenamyre JT, Hastings TG (2004) Biomedicine. Parkinson's - divergent causes, convergent mechanisms. Science 304: 1120-1122.
    • (2004) Science , vol.304 , pp. 1120-1122
    • Greenamyre, J.T.1    Hastings, T.G.2
  • 62
    • 0031859395 scopus 로고    scopus 로고
    • Mitochondrial DNA transmission of the mitochondrial defect in Parkinson's disease
    • Gu M, Cooper JM, Taanman JW, Schapira AH (1998) Mitochondrial DNA transmission of the mitochondrial defect in Parkinson's disease. Ann Neurol 44: 177-186.
    • (1998) Ann Neurol , vol.44 , pp. 177-186
    • Gu, M.1    Cooper, J.M.2    Taanman, J.W.3    Schapira, A.H.4
  • 63
    • 0031052381 scopus 로고    scopus 로고
    • Amyloid, the presenilins and Alzheimer's disease
    • Hardy J (1997) Amyloid, the presenilins and Alzheimer's disease. Trends Neurosci 20: 154-159.
    • (1997) Trends Neurosci , vol.20 , pp. 154-159
    • Hardy, J.1
  • 64
    • 0015319592 scopus 로고
    • The biologic clock: The mitochondria?
    • Harman D (1972) The biologic clock: The mitochondria? J Am Geriatr Soc 20: 145-147.
    • (1972) J Am Geriatr Soc , vol.20 , pp. 145-147
    • Harman, D.1
  • 65
    • 0031771518 scopus 로고    scopus 로고
    • Interaction of alpha-phenyl-N-tert-butyl nitrone and alternative electron acceptors with complex I indicates a substrate reduction site upstream from the rotenone binding site
    • Hensley K, Pye QN, Maidt ML, Stewart CA, Robinson KA, Jaffrey F, Floyd RA (1998) Interaction of alpha-phenyl-N-tert-butyl nitrone and alternative electron acceptors with complex I indicates a substrate reduction site upstream from the rotenone binding site. J Neurochem 71:2549-2557.
    • (1998) J Neurochem , vol.71 , pp. 2549-2557
    • Hensley, K.1    Pye, Q.N.2    Maidt, M.L.3    Stewart, C.A.4    Robinson, K.A.5    Jaffrey, F.6    Floyd, R.A.7
  • 67
    • 0030813676 scopus 로고    scopus 로고
    • Population genetics and disease susceptibility: Characterization of central European haplogroups by mtDNA gene mutations, correlation with D loop variants and association with disease
    • Hofmann S, Jaksch M, Bezold R, Mertens S, Aholt S, Paprotta A, Gerbitz KD (1997) Population genetics and disease susceptibility: Characterization of central European haplogroups by mtDNA gene mutations, correlation with D loop variants and association with disease. Hum Mol Genet 6: 1835-1846.
    • (1997) Hum Mol Genet , vol.6 , pp. 1835-1846
    • Hofmann, S.1    Jaksch, M.2    Bezold, R.3    Mertens, S.4    Aholt, S.5    Paprotta, A.6    Gerbitz, K.D.7
  • 68
    • 0035012777 scopus 로고    scopus 로고
    • High incidence of single nucleotide substitutions in the mitochondrial genome is associated with poor semen parameters in men
    • Holyoake AJ, McHugh P, Wu M, O'Carroll S, Benny P, Sin IL, Sin FY (2001) High incidence of single nucleotide substitutions in the mitochondrial genome is associated with poor semen parameters in men. Int J Androl 24: 175-182.
    • (2001) Int J Androl , vol.24 , pp. 175-182
    • Holyoake, A.J.1    McHugh, P.2    Wu, M.3    O'Carroll, S.4    Benny, P.5    Sin, I.L.6    Sin, F.Y.7
  • 71
    • 0029396761 scopus 로고
    • The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part IX. A prospective cliniconeuropathologic study of Parkinson's features in Alzheimer's disease
    • Hulette C, Mirra S, Wilkinson W, Heyman A, Fillenbaum G, Clark C (1995) The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part IX. A prospective cliniconeuropathologic study of Parkinson's features in Alzheimer's disease. Neurology 45: 1991-1995.
    • (1995) Neurology , vol.45 , pp. 1991-1995
    • Hulette, C.1    Mirra, S.2    Wilkinson, W.3    Heyman, A.4    Fillenbaum, G.5    Clark, C.6
  • 72
    • 0029091194 scopus 로고
    • A mitochondrial DNA clone is associated with increased risk for Alzheimer disease
    • U S A
    • Hutchin T, Cortopassi G (1995) A mitochondrial DNA clone is associated with increased risk for Alzheimer disease. Proc Natl Acad Sci U S A 92: 6892-6895.
    • (1995) Proc Natl Acad Sci , vol.92 , pp. 6892-6895
    • Hutchin, T.1    Cortopassi, G.2
  • 73
    • 0031796015 scopus 로고    scopus 로고
    • Mitochondrial genotype associated with French Caucasian centenarians
    • Ivanova R, Lepage V, Charron D, Schachter F (1998) Mitochondrial genotype associated with French Caucasian centenarians. Gerontology 44: 349.
    • (1998) Gerontology , vol.44 , pp. 349
    • Ivanova, R.1    Lepage, V.2    Charron, D.3    Schachter, F.4
  • 74
    • 0026036025 scopus 로고
    • Alternative, simultaneous complex I mitochondrial DNA mutations in Leber's hereditary optic neuropathy
    • Johns DR, Berman J (1991) Alternative, simultaneous complex I mitochondrial DNA mutations in Leber's hereditary optic neuropathy. Biochem Biophys Res Commun 174: 1324-1330.
    • (1991) Biochem Biophys Res Commun , vol.174 , pp. 1324-1330
    • Johns, D.R.1    Berman, J.2
  • 75
    • 2342429459 scopus 로고    scopus 로고
    • DNA polymerase gamma, the mitochondrial replicase
    • Kaguni LS (2004) DNA polymerase gamma, the mitochondrial replicase. Annu Rev Biochem 73: 293-320.
    • (2004) Annu Rev Biochem , vol.73 , pp. 293-320
    • Kaguni, L.S.1
  • 76
    • 14644422657 scopus 로고    scopus 로고
    • Alterations of mitochondrial DNA in common diseases and disease states: Aging, neurodegeneration, heart failure, diabetes, and cancer
    • Kang D, Hamasaki N (2005) Alterations of mitochondrial DNA in common diseases and disease states: Aging, neurodegeneration, heart failure, diabetes, and cancer. Curr Med Chem 12: 429-441.
    • (2005) Curr Med Chem , vol.12 , pp. 429-441
    • Kang, D.1    Hamasaki, N.2
  • 80
    • 0042387705 scopus 로고    scopus 로고
    • Phylogeny of east Asian mitochondrial DNA lineages inferred from complete sequences
    • Kong QP, Yao YG, Sun C, Bandelt HJ, Zhu CL, Zhang YP (2003) Phylogeny of east Asian mitochondrial DNA lineages inferred from complete sequences. Am J Hum Genet 73: 671-676.
    • (2003) Am J Hum Genet , vol.73 , pp. 671-676
    • Kong, Q.P.1    Yao, Y.G.2    Sun, C.3    Bandelt, H.J.4    Zhu, C.L.5    Zhang, Y.P.6
  • 81
    • 8844254726 scopus 로고    scopus 로고
    • Apolipoprotein Abeta: Black sheep in a good family
    • Kontush A (2004) Apolipoprotein Abeta: Black sheep in a good family. Brain Pathol 14: 433-447.
    • (2004) Brain Pathol , vol.14 , pp. 433-447
    • Kontush, A.1
  • 82
    • 1842555337 scopus 로고    scopus 로고
    • Alzheimer's amyloid-beta (A beta) is an essential synaptic protein, not neurotoxic junk
    • Koudinov AR, Berezov TT (2004) Alzheimer's amyloid-beta (A beta) is an essential synaptic protein, not neurotoxic junk. Acta Neurobiol Exp (Wars) 64: 71-79.
    • (2004) Acta Neurobiol Exp (Wars) , vol.64 , pp. 71-79
    • Koudinov, A.R.1    Berezov, T.T.2
  • 84
    • 0032829070 scopus 로고    scopus 로고
    • Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure
    • Langston JW, Forno LS, Tetrud J, Reeves AG, Kaplan JA, Karluk D (1999) Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure. Ann Neurol 46: 598-605.
    • (1999) Ann Neurol , vol.46 , pp. 598-605
    • Langston, J.W.1    Forno, L.S.2    Tetrud, J.3    Reeves, A.G.4    Kaplan, J.A.5    Karluk, D.6
  • 85
    • 0033964762 scopus 로고    scopus 로고
    • Mitochondrial role in life and death of the cell
    • Lee HC, Wei YH (2000) Mitochondrial role in life and death of the cell. J Biomed Sci 7: 2-15.
    • (2000) J Biomed Sci , vol.7 , pp. 2-15
    • Lee, H.C.1    Wei, Y.H.2
  • 87
    • 0037081814 scopus 로고    scopus 로고
    • High aggregate burden of somatic mtDNA point mutations in aging and Alzheimer's disease brain
    • Lin MT, Simon DK, Ahn CH, Kim LM, Beal MF (2002) High aggregate burden of somatic mtDNA point mutations in aging and Alzheimer's disease brain. Hum Mol Genet 11: 133-145.
    • (2002) Hum Mol Genet , vol.11 , pp. 133-145
    • Lin, M.T.1    Simon, D.K.2    Ahn, C.H.3    Kim, L.M.4    Beal, M.F.5
  • 88
    • 0024541837 scopus 로고
    • Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases
    • Linnane AW, Marzuki S, Ozawa T, Tanaka M (1989) Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases. Lancet 1: 642-645.
    • (1989) Lancet , vol.1 , pp. 642-645
    • Linnane, A.W.1    Marzuki, S.2    Ozawa, T.3    Tanaka, M.4
  • 92
    • 0033937733 scopus 로고    scopus 로고
    • The role of mitochondria in the pathogenesis of neurodegenerative diseases
    • Manfredi G, Beal MF (2000) The role of mitochondria in the pathogenesis of neurodegenerative diseases. Brain Pathol 10: 462-472.
    • (2000) Brain Pathol , vol.10 , pp. 462-472
    • Manfredi, G.1    Beal, M.F.2
  • 93
    • 33644534495 scopus 로고    scopus 로고
    • From structural biochemistry to expression profiling: Neuroprotective activities of estrogen
    • Manthey D, Behl C (2006) From structural biochemistry to expression profiling: Neuroprotective activities of estrogen. Neuroscience 138: 845-850.
    • (2006) Neuroscience , vol.138 , pp. 845-850
    • Manthey, D.1    Behl, C.2
  • 96
    • 0028152717 scopus 로고
    • Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease
    • Mecocci P, MacGarvey U, Beal MF (1994) Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease. Ann Neurol 36: 747-751.
    • (1994) Ann Neurol , vol.36 , pp. 747-751
    • Mecocci, P.1    MacGarvey, U.2    Beal, M.F.3
  • 97
    • 4544307465 scopus 로고    scopus 로고
    • Modeling mitochondrial function in aging neurons
    • Melov S (2004) Modeling mitochondrial function in aging neurons. Trends Neurosci 27: 601-606.
    • (2004) Trends Neurosci , vol.27 , pp. 601-606
    • Melov, S.1
  • 100
    • 0035692636 scopus 로고    scopus 로고
    • DJ-1 is an indicator for endogenous reactive oxygen species elicited by endotoxin
    • Mitsumoto A, Nakagawa Y (2001) DJ-1 is an indicator for endogenous reactive oxygen species elicited by endotoxin. Free Radic Res 35: 885-893.
    • (2001) Free Radic Res , vol.35 , pp. 885-893
    • Mitsumoto, A.1    Nakagawa, Y.2
  • 101
    • 0029765553 scopus 로고    scopus 로고
    • Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides
    • Miyata M, Smith JD (1996) Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides. Nat Genet 14: 55-61.
    • (1996) Nat Genet , vol.14 , pp. 55-61
    • Miyata, M.1    Smith, J.D.2
  • 104
    • 0141510019 scopus 로고    scopus 로고
    • Oxidative damage to mitochondrial complex I due to peroxynitrite: Identification of reactive tyrosines by mass spectrometry
    • Murray J, Taylor SW, Zhang B, Ghosh SS, Capaldi RA (2003) Oxidative damage to mitochondrial complex I due to peroxynitrite: Identification of reactive tyrosines by mass spectrometry. J Biol Chem 278: 37223-37230.
    • (2003) J Biol Chem , vol.278 , pp. 37223-37230
    • Murray, J.1    Taylor, S.W.2    Zhang, B.3    Ghosh, S.S.4    Capaldi, R.A.5
  • 105
    • 0035758117 scopus 로고    scopus 로고
    • Hunting genes in Parkinson's disease from the roots
    • Muthane U, Jain S, Gururaj G (2001) Hunting genes in Parkinson's disease from the roots. Med Hypotheses 57: 51-55.
    • (2001) Med Hypotheses , vol.57 , pp. 51-55
    • Muthane, U.1    Jain, S.2    Gururaj, G.3
  • 107
    • 0037209210 scopus 로고    scopus 로고
    • Mitochondrial DNA polymorphisms associated with longevity in a Finnish population
    • Niemi AK, Hervonen A, Hurme M, Karhunen PJ, Jylha M, Majamaa K (2003) Mitochondrial DNA polymorphisms associated with longevity in a Finnish population. Hum Genet 112: 29-33.
    • (2003) Hum Genet , vol.112 , pp. 29-33
    • Niemi, A.K.1    Hervonen, A.2    Hurme, M.3    Karhunen, P.J.4    Jylha, M.5    Majamaa, K.6
  • 110
    • 14644446028 scopus 로고    scopus 로고
    • Activation of p38 and N-acetylcysteine-sensitive c-Jun NH2-terminal kinase signaling cascades is required for induction of apoptosis in Parkinson's disease cybrids
    • Onyango IG, Tuttle JB, Bennett JP, Jr. (2005) Activation of p38 and N-acetylcysteine-sensitive c-Jun NH2-terminal kinase signaling cascades is required for induction of apoptosis in Parkinson's disease cybrids. Mol Cell Neurosci 28: 452-461.
    • (2005) Mol Cell Neurosci , vol.28 , pp. 452-461
    • Onyango, I.G.1    Tuttle, J.B.2    Bennett Jr., J.P.3
  • 111
    • 0036182026 scopus 로고    scopus 로고
    • Mitochondrial involvement in Parkinson's disease
    • Orth M, Schapira AH (2002) Mitochondrial involvement in Parkinson's disease. Neurochem Int 40: 533-541.
    • (2002) Neurochem Int , vol.40 , pp. 533-541
    • Orth, M.1    Schapira, A.H.2
  • 113
    • 0024848034 scopus 로고
    • Abnormalities of the electron transport chain in idiopathic Parkinson's disease
    • Parker WD, Jr., Boyson SJ, Parks JK (1989) Abnormalities of the electron transport chain in idiopathic Parkinson's disease. Ann Neurol 26: 719-723.
    • (1989) Ann Neurol , vol.26 , pp. 719-723
    • Parker Jr., W.D.1    Boyson, S.J.2    Parks, J.K.3
  • 116
    • 13244256956 scopus 로고    scopus 로고
    • Comparison between the Polish population and European populations on the basis of mitochondrial morphs and haplogroups
    • Piechota J, Tonska K, Nowak M, Kabzinska D, Lorenc A, Bartnik E (2004) Comparison between the Polish population and European populations on the basis of mitochondrial morphs and haplogroups. Acta Biochim Pol 51: 883-895.
    • (2004) Acta Biochim Pol , vol.51 , pp. 883-895
    • Piechota, J.1    Tonska, K.2    Nowak, M.3    Kabzinska, D.4    Lorenc, A.5    Bartnik, E.6
  • 118
    • 33644845279 scopus 로고    scopus 로고
    • Amyloid precursor protein-mediated free radicals and oxidative damage: Implications for the development and progression of Alzheimer's disease
    • Reddy PH (2006) Amyloid precursor protein-mediated free radicals and oxidative damage: Implications for the development and progression of Alzheimer's disease. J Neurochem 96: 1-13.
    • (2006) J Neurochem , vol.96 , pp. 1-13
    • Reddy, P.H.1
  • 119
    • 27544484846 scopus 로고    scopus 로고
    • Are mitochondria critical in the pathogenesis of Alzheimer's disease?
    • Reddy PH, Beal MF (2005) Are mitochondria critical in the pathogenesis of Alzheimer's disease? Brain Res Brain Res Rev 49: 618-632.
    • (2005) Brain Res Brain Res Rev , vol.49 , pp. 618-632
    • Reddy, P.H.1    Beal, M.F.2
  • 120
    • 0036827161 scopus 로고    scopus 로고
    • Abeta as a bioflocculant: Implications for the amyloid hypothesis of Alzheimer's disease
    • Robinson SR, Bishop GM (2002) Abeta as a bioflocculant: implications for the amyloid hypothesis of Alzheimer's disease. Neurobiol Aging 23: 1051-1072.
    • (2002) Neurobiol Aging , vol.23 , pp. 1051-1072
    • Robinson, S.R.1    Bishop, G.M.2
  • 121
    • 0035058647 scopus 로고    scopus 로고
    • Is mitochondrial DNA depletion involved in Alzheimer's disease?
    • Rodriguez-Santiago B, Casademont J, Nunes V (2001) Is mitochondrial DNA depletion involved in Alzheimer's disease? Eur J Hum Genet 9: 279-285.
    • (2001) Eur J Hum Genet , vol.9 , pp. 279-285
    • Rodriguez-Santiago, B.1    Casademont, J.2    Nunes, V.3
  • 125
    • 0036862315 scopus 로고    scopus 로고
    • Is amyloid beta-peptide neurotoxic or neuroprotective and what is its role in the binding of metal ions?
    • Savory J, Ghribi O, Herman MM (2002) Is amyloid beta-peptide neurotoxic or neuroprotective and what is its role in the binding of metal ions? Neurobiol Aging 23: 1089-1092.
    • (2002) Neurobiol Aging , vol.23 , pp. 1089-1092
    • Savory, J.1    Ghribi, O.2    Herman, M.M.3
  • 126
    • 0032813088 scopus 로고    scopus 로고
    • Repair of DNA damage in mitochondria
    • Sawyer DE, Van Houten B (1999) Repair of DNA damage in mitochondria. Mutat Res 434: 161-176.
    • (1999) Mutat Res , vol.434 , pp. 161-176
    • Sawyer, D.E.1    Van Houten, B.2
  • 127
    • 0035990290 scopus 로고    scopus 로고
    • Primary and secondary defects of the mitochondrial respiratory chain
    • Schapira AH (2002) Primary and secondary defects of the mitochondrial respiratory chain. J Inherit Metab Dis 25: 207-214.
    • (2002) J Inherit Metab Dis , vol.25 , pp. 207-214
    • Schapira, A.H.1
  • 130
    • 0032211830 scopus 로고    scopus 로고
    • The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease
    • Selkoe DJ (1998) The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease. Trends Cell Biol 8: 447-453.
    • (1998) Trends Cell Biol , vol.8 , pp. 447-453
    • Selkoe, D.J.1
  • 131
    • 0037104723 scopus 로고    scopus 로고
    • An in vitro model of Parkinson's disease: Linking mitochondrial impairment to altered alpha-synuclein metabolism and oxidative damage
    • Sherer TB, Betarbet R, Stout AK, Lund S, Baptista M, Panov AV, Cookson MR, Greenamyre JT (2002) An in vitro model of Parkinson's disease: Linking mitochondrial impairment to altered alpha-synuclein metabolism and oxidative damage. J Neurosci 22: 7006-7015.
    • (2002) J Neurosci , vol.22 , pp. 7006-7015
    • Sherer, T.B.1    Betarbet, R.2    Stout, A.K.3    Lund, S.4    Baptista, M.5    Panov, A.V.6    Cookson, M.R.7    Greenamyre, J.T.8
  • 135
    • 0034620483 scopus 로고    scopus 로고
    • Mitochondrial DNA mutations in complex I and tRNA genes in Parkinson's disease
    • Simon DK, Mayeux R, Marder K, Kowall NW, Beal MF, Johns DR (2000) Mitochondrial DNA mutations in complex I and tRNA genes in Parkinson's disease. Neurology 54: 703-709.
    • (2000) Neurology , vol.54 , pp. 703-709
    • Simon, D.K.1    Mayeux, R.2    Marder, K.3    Kowall, N.W.4    Beal, M.F.5    Johns, D.R.6
  • 138
    • 4644351698 scopus 로고    scopus 로고
    • High frequency of mitochondrial complex I mutations in Parkinson's disease and aging
    • Smigrodzki R, Parks J, Parker WD (2004) High frequency of mitochondrial complex I mutations in Parkinson's disease and aging. Neurobiol Aging 25: 1273-1281.
    • (2004) Neurobiol Aging , vol.25 , pp. 1273-1281
    • Smigrodzki, R.1    Parks, J.2    Parker, W.D.3
  • 139
    • 24944435398 scopus 로고    scopus 로고
    • Mitochondrial microheteroplasmy and a theory of aging and age-related disease
    • Smigrodzki RM, Khan SM (2005) Mitochondrial microheteroplasmy and a theory of aging and age-related disease. Rejuvenation Res 8: 172-198.
    • (2005) Rejuvenation Res , vol.8 , pp. 172-198
    • Smigrodzki, R.M.1    Khan, S.M.2
  • 141
    • 17044364766 scopus 로고    scopus 로고
    • DNA precursor asymmetries in mammalian tissue mitochondria and possible contribution to mutagenesis through reduced replication fidelity
    • U S A
    • Song S, Pursell ZF, Copeland WC, Longley MJ, Kunkel TA, Mathews CK (2005) DNA precursor asymmetries in mammalian tissue mitochondria and possible contribution to mutagenesis through reduced replication fidelity. Proc Natl Acad Sci U S A 102: 4990-4995.
    • (2005) Proc Natl Acad Sci , vol.102 , pp. 4990-4995
    • Song, S.1    Pursell, Z.F.2    Copeland, W.C.3    Longley, M.J.4    Kunkel, T.A.5    Mathews, C.K.6
  • 145
    • 0032504575 scopus 로고    scopus 로고
    • Mitochondria as regulators of apoptosis: Doubt no more
    • Susin SA, Zamzami N, Kroemer G (1998) Mitochondria as regulators of apoptosis: Doubt no more. Biochim Biophys Acta 1366: 151-165.
    • (1998) Biochim Biophys Acta , vol.1366 , pp. 151-165
    • Susin, S.A.1    Zamzami, N.2    Kroemer, G.3
  • 146
    • 3042806534 scopus 로고    scopus 로고
    • A "mitochondrial cascade hypothesis" for sporadic Alzheimer's disease
    • Swerdlow RH, Khan SM (2004) A "mitochondrial cascade hypothesis" for sporadic Alzheimer's disease. Med Hypotheses 63: 8-20.
    • (2004) Med Hypotheses , vol.63 , pp. 8-20
    • Swerdlow, R.H.1    Khan, S.M.2
  • 147
    • 0036982389 scopus 로고    scopus 로고
    • Mitochondria in Alzheimer's disease
    • Swerdlow RH, Kish SJ (2002) Mitochondria in Alzheimer's disease. Int Rev Neurobiol 53: 341-385.
    • (2002) Int Rev Neurobiol , vol.53 , pp. 341-385
    • Swerdlow, R.H.1    Kish, S.J.2
  • 149
    • 0032539447 scopus 로고    scopus 로고
    • Mitochondrial genotype associated with longevity
    • Tanaka M, Gong JS, Zhang J, Yoneda M, Yagi K (1998) Mitochondrial genotype associated with longevity. Lancet 351: 185-186.
    • (1998) Lancet , vol.351 , pp. 185-186
    • Tanaka, M.1    Gong, J.S.2    Zhang, J.3    Yoneda, M.4    Yagi, K.5
  • 150
    • 0034738386 scopus 로고    scopus 로고
    • Mitochondrial genotype associated with longevity and its inhibitory effect on mutagenesis
    • Tanaka M, Gong J, Zhang J, Yamada Y, Borgeld HJ, Yagi K (2000) Mitochondrial genotype associated with longevity and its inhibitory effect on mutagenesis. Mech Ageing Dev 116: 65-76.
    • (2000) Mech Ageing Dev , vol.116 , pp. 65-76
    • Tanaka, M.1    Gong, J.2    Zhang, J.3    Yamada, Y.4    Borgeld, H.J.5    Yagi, K.6
  • 151
    • 2342620627 scopus 로고    scopus 로고
    • Mitochondrial genome single nucleotide polymorphisms and their phenotypes in the Japanese
    • Tanaka M, Takeyasu T, Fuku N, Li-Jun G, Kurata M (2004) Mitochondrial genome single nucleotide polymorphisms and their phenotypes in the Japanese. Ann N Y Acad Sci 1011: 7-20.
    • (2004) Ann N Y Acad Sci , vol.1011 , pp. 7-20
    • Tanaka, M.1    Takeyasu, T.2    Fuku, N.3    Li-Jun, G.4    Kurata, M.5
  • 152
    • 12844288997 scopus 로고    scopus 로고
    • Widespread gamma-secretase activity in the cell, but do we need it at the mitochondria?
    • Teng FY, Tang BL (2005) Widespread gamma-secretase activity in the cell, but do we need it at the mitochondria? Biochem Biophys Res Commun 328: 1-5.
    • (2005) Biochem Biophys Res Commun , vol.328 , pp. 1-5
    • Teng, F.Y.1    Tang, B.L.2
  • 153
    • 0028332916 scopus 로고
    • Mitochondrial DNA variation in human populations and implications for detection of mitochondrial DNA mutations of pathological significance
    • Torroni A, Wallace DC (1994) Mitochondrial DNA variation in human populations and implications for detection of mitochondrial DNA mutations of pathological significance. J Bioenerg Biomembr 26: 261-271.
    • (1994) J Bioenerg Biomembr , vol.26 , pp. 261-271
    • Torroni, A.1    Wallace, D.C.2
  • 159
    • 28444445608 scopus 로고    scopus 로고
    • Enhanced ROS production and antioxidant defenses in cybrids harbouring mutations in mtDNA
    • Vives-Bauza C, Gonzalo R, Manfredi G, Garcia-Arumi E, Andreu AL (2006) Enhanced ROS production and antioxidant defenses in cybrids harbouring mutations in mtDNA. Neurosci Lett 391: 136-141.
    • (2006) Neurosci Lett , vol.391 , pp. 136-141
    • Vives-Bauza, C.1    Gonzalo, R.2    Manfredi, G.3    Garcia-Arumi, E.4    Andreu, A.L.5
  • 160
    • 0032833421 scopus 로고    scopus 로고
    • Mitochondrial DNA variation in human evolution and disease
    • Wallace DC, Brown MD, Lott MT (1999) Mitochondrial DNA variation in human evolution and disease. Gene 238: 211-230.
    • (1999) Gene , vol.238 , pp. 211-230
    • Wallace, D.C.1    Brown, M.D.2    Lott, M.T.3
  • 161
    • 0028843809 scopus 로고
    • No association found between Alzheimer's disease and a mitochondrial tRNA glutamine gene variant
    • Wragg MA, Talbot CJ, Morris JC, Lendon CL, Goate AM (1995) No association found between Alzheimer's disease and a mitochondrial tRNA glutamine gene variant. Neurosci Lett 201: 107-110.
    • (1995) Neurosci Lett , vol.201 , pp. 107-110
    • Wragg, M.A.1    Talbot, C.J.2    Morris, J.C.3    Lendon, C.L.4    Goate, A.M.5
  • 162
    • 0026457825 scopus 로고
    • Marked replicative advantage of human mtDNA carrying a point mutation that causes the MELAS encephalomyopathy
    • U S A
    • Yoneda M, Chomyn A, Martinuzzi A, Hurko O, Attardi G (1992) Marked replicative advantage of human mtDNA carrying a point mutation that causes the MELAS encephalomyopathy. Proc Natl Acad Sci U S A 89: 11164-11168.
    • (1992) Proc Natl Acad Sci , vol.89 , pp. 11164-11168
    • Yoneda, M.1    Chomyn, A.2    Martinuzzi, A.3    Hurko, O.4    Attardi, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.