-
1
-
-
33644543761
-
Expanding insights of mitochondrial dysfunction in Parkinson's disease
-
Abou-Sleiman PM, Muqit MM, Wood NW (2006) Expanding insights of mitochondrial dysfunction in Parkinson's disease. Nat Rev Neurosci 7: 207-219.
-
(2006)
Nat Rev Neurosci
, vol.7
, pp. 207-219
-
-
Abou-Sleiman, P.M.1
Muqit, M.M.2
Wood, N.W.3
-
2
-
-
0030878073
-
Oxidative DNA damage in the parkinsonian brain: An apparent selective increase in 8-hydroxyguanine levels in substantia nigra
-
Alam ZI, Jenner A, Daniel SE, Lees AJ, Cairns N, Marsden CD, Jenner P, Halliwell B (1997) Oxidative DNA damage in the parkinsonian brain: an apparent selective increase in 8-hydroxyguanine levels in substantia nigra. J Neurochem 69: 1196-1203.
-
(1997)
J Neurochem
, vol.69
, pp. 1196-1203
-
-
Alam, Z.I.1
Jenner, A.2
Daniel, S.E.3
Lees, A.J.4
Cairns, N.5
Marsden, C.D.6
Jenner, P.7
Halliwell, B.8
-
3
-
-
26444588771
-
Gradual alteration of mitochondrial structure and function by beta-amyloids: Importance of membrane viscosity changes, energy deprivation, reactive oxygen species production, and cytochrome c release
-
Aleardi AM, Benard G, Augereau O, Malgat M, Talbot JC, Mazat JP, Letellier T, Dachary-Prigent J, Solaini GC, Rossignol R (2005) Gradual alteration of mitochondrial structure and function by beta-amyloids: Importance of membrane viscosity changes, energy deprivation, reactive oxygen species production, and cytochrome c release. J Bioenerg Biomembr 37: 207-225.
-
(2005)
J Bioenerg Biomembr
, vol.37
, pp. 207-225
-
-
Aleardi, A.M.1
Benard, G.2
Augereau, O.3
Malgat, M.4
Talbot, J.C.5
Mazat, J.P.6
Letellier, T.7
Dachary-Prigent, J.8
Solaini, G.C.9
Rossignol, R.10
-
4
-
-
0036847136
-
Characterization of the Caucasian haplogroups present in the SWGDAM forensic mtDNA dataset for 1771 human control region sequences
-
Scientific Working Group on DNA Analysis Methods
-
Allard MW, Miller K, Wilson M, Monson K, Budowle B (2002) Characterization of the Caucasian haplogroups present in the SWGDAM forensic mtDNA dataset for 1771 human control region sequences. Scientific Working Group on DNA Analysis Methods. J Forensic Sci 47: 1215-1223.
-
(2002)
J Forensic Sci
, vol.47
, pp. 1215-1223
-
-
Allard, M.W.1
Miller, K.2
Wilson, M.3
Monson, K.4
Budowle, B.5
-
5
-
-
0037437192
-
Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells
-
Anandatheerthavarada HK, Biswas G, Robin MA, Avadhani NG (2003) Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells. J Cell Biol 161:41-54.
-
(2003)
J Cell Biol
, vol.161
, pp. 41-54
-
-
Anandatheerthavarada, H.K.1
Biswas, G.2
Robin, M.A.3
Avadhani, N.G.4
-
6
-
-
0036965466
-
Endogenous risk factors in Parkinson's disease: Dopamine and tetrahydroisoquinolines
-
Antkiewicz-Michaluk L (2002) Endogenous risk factors in Parkinson's disease: dopamine and tetrahydroisoquinolines. Pol J Pharmacol 54: 567-572.
-
(2002)
Pol J Pharmacol
, vol.54
, pp. 567-572
-
-
Antkiewicz-Michaluk, L.1
-
7
-
-
0141853765
-
Amyloid-beta: A chameleon walking in two worlds: A review of the trophic and toxic properties of amyloid-beta
-
Atwood CS, Obrenovich ME, Liu T, Chan H, Perry G, Smith MA, Martins RN (2003) Amyloid-beta: a chameleon walking in two worlds: a review of the trophic and toxic properties of amyloid-beta. Brain Res Brain Res Rev 43: 1-16.
-
(2003)
Brain Res Brain Res Rev
, vol.43
, pp. 1-16
-
-
Atwood, C.S.1
Obrenovich, M.E.2
Liu, T.3
Chan, H.4
Perry, G.5
Smith, M.A.6
Martins, R.N.7
-
8
-
-
2942750228
-
Mitochondrial DNA polymorphisms as risk factors for Parkinson's disease and Parkinson's disease dementia
-
Autere J, Moilanen JS, Finnila S, Soininen H, Mannermaa A, Hartikainen P, Hallikainen M, Majamaa K (2004) Mitochondrial DNA polymorphisms as risk factors for Parkinson's disease and Parkinson's disease dementia. Hum Genet 115:29-35.
-
(2004)
Hum Genet
, vol.115
, pp. 29-35
-
-
Autere, J.1
Moilanen, J.S.2
Finnila, S.3
Soininen, H.4
Mannermaa, A.5
Hartikainen, P.6
Hallikainen, M.7
Majamaa, K.8
-
9
-
-
0030915207
-
Mitochondrial DNA polymorphisms in pathologically proven Parkinson's disease
-
Bandmann O, Sweeney MG, Daniel SE, Marsden CD, Wood NW (1997) Mitochondrial DNA polymorphisms in pathologically proven Parkinson's disease. J Neurol 244: 262-265.
-
(1997)
J Neurol
, vol.244
, pp. 262-265
-
-
Bandmann, O.1
Sweeney, M.G.2
Daniel, S.E.3
Marsden, C.D.4
Wood, N.W.5
-
10
-
-
0032504710
-
Mitochondrial dysfunction in neurodegenerative diseases
-
Beal MF (1998) Mitochondrial dysfunction in neurodegenerative diseases. Biochim Biophys Acta 1366: 211-223.
-
(1998)
Biochim Biophys Acta
, vol.1366
, pp. 211-223
-
-
Beal, M.F.1
-
11
-
-
0037098866
-
Antioxidant neuroprotection in Alzheimer's disease as preventive and therapeutic approach
-
Behl C, Moosmann B (2002) Antioxidant neuroprotection in Alzheimer's disease as preventive and therapeutic approach. Free Radic Biol Med 33: 182-191.
-
(2002)
Free Radic Biol Med
, vol.33
, pp. 182-191
-
-
Behl, C.1
Moosmann, B.2
-
12
-
-
33646375711
-
High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease
-
Bender A, Krishnan KJ, Morris CM, Taylor GA, Reeve AK, Perry RH, Jaros E, Hersheson JS, Betts J, Klopstock T, Taylor RW, Turnbull DM (2006) High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease. Nat Genet 38: 515-517.
-
(2006)
Nat Genet
, vol.38
, pp. 515-517
-
-
Bender, A.1
Krishnan, K.J.2
Morris, C.M.3
Taylor, G.A.4
Reeve, A.K.5
Perry, R.H.6
Jaros, E.7
Hersheson, J.S.8
Betts, J.9
Klopstock, T.10
Taylor, R.W.11
Turnbull, D.M.12
-
13
-
-
0035906328
-
Mitochondrial DNA in aging and degenerative disease
-
Berdanier CD, Everts HB (2001) Mitochondrial DNA in aging and degenerative disease. Mutat Res 475: 169-183.
-
(2001)
Mutat Res
, vol.475
, pp. 169-183
-
-
Berdanier, C.D.1
Everts, H.B.2
-
14
-
-
0033681149
-
Chronic systemic pesticide exposure reproduces features of Parkinson's disease
-
Betarbet R, Sherer TB, MacKenzie G, Garcia-Osuna M, Panov AV, Greenamyre JT (2000) Chronic systemic pesticide exposure reproduces features of Parkinson's disease. Nat Neurosci 3: 1301-1306.
-
(2000)
Nat Neurosci
, vol.3
, pp. 1301-1306
-
-
Betarbet, R.1
Sherer, T.B.2
MacKenzie, G.3
Garcia-Osuna, M.4
Panov, A.V.5
Greenamyre, J.T.6
-
16
-
-
33745612296
-
Intersecting pathways to neurodegeneration in Parkinson's disease: Effects of the pesticide rotenone on DJ-1, alpha-synuclein, and the ubiquitin-proteasome system
-
Betarbet R, Canet-Aviles RM, Sherer TB, Mastroberardino PG, McLendon C, Kim JH, Lund S, Na HM, Taylor G, Bence NF, Kopito R, Seo BB, Yagi T, Yagi A, Klinefelter G, Cookson MR, Greenamyre JT (2006) Intersecting pathways to neurodegeneration in Parkinson's disease: Effects of the pesticide rotenone on DJ-1, alpha-synuclein, and the ubiquitin-proteasome system. Neurobiol Dis 22: 404-420.
-
(2006)
Neurobiol Dis
, vol.22
, pp. 404-420
-
-
Betarbet, R.1
Canet-Aviles, R.M.2
Sherer, T.B.3
Mastroberardino, P.G.4
McLendon, C.5
Kim, J.H.6
Lund, S.7
Na, H.M.8
Taylor, G.9
Bence, N.F.10
Kopito, R.11
Seo, B.B.12
Yagi, T.13
Yagi, A.14
Klinefelter, G.15
Cookson, M.R.16
Greenamyre, J.T.17
-
17
-
-
0037428241
-
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
-
Bonifati V, Rizzu P, van Baren MJ, Schaap O, Breedveld GJ, Krieger E, Dekker MC, Squitieri F, Ibanez P, Joosse M, van Dongen JW, Vanacore N, van Swieten JC, Brice A, Meco G, van Duijn CM, Oostra BA, Heutink P (2003) Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism. Science 299: 256-259.
-
(2003)
Science
, vol.299
, pp. 256-259
-
-
Bonifati, V.1
Rizzu, P.2
Van Baren, M.J.3
Schaap, O.4
Breedveld, G.J.5
Krieger, E.6
Dekker, M.C.7
Squitieri, F.8
Ibanez, P.9
Joosse, M.10
Van Dongen, J.W.11
Vanacore, N.12
Van Swieten, J.C.13
Brice, A.14
Meco, G.15
Van Duijn, C.M.16
Oostra, B.A.17
Heutink, P.18
-
18
-
-
22044432781
-
Early-onset parkinsonism associated with PINK1 mutations: Frequency, genotypes, and phenotypes
-
Bonifati V, Rohe CF, Breedveld GJ, Fabrizio E, De Mari M, Tassorelli C, Tavella A, Marconi R, Nicholl DJ, Chien HF, Fincati E, Abbruzzese G, Marini P, De Gaetano A, Horstink MW, Maat-Kievit JA, Sampaio C, Antonini A, Stocchi F, Montagna P, Toni V, Guidi M, Dalla Libera A, Tinazzi M, De Pandis F, Fabbrini G, Goldwurm S, de Klein A, Barbosa E, Lopiano L, Martignoni E, Lamberti P, Vanacore N, Meco G, Oostra BA (2005) Early-onset parkinsonism associated with PINK1 mutations: frequency, genotypes, and phenotypes. Neurology 65: 87-95.
-
(2005)
Neurology
, vol.65
, pp. 87-95
-
-
Bonifati, V.1
Rohe, C.F.2
Breedveld, G.J.3
Fabrizio, E.4
De Mari, M.5
Tassorelli, C.6
Tavella, A.7
Marconi, R.8
Nicholl, D.J.9
Chien, H.F.10
Fincati, E.11
Abbruzzese, G.12
Marini, P.13
De Gaetano, A.14
Horstink, M.W.15
Maat-Kievit, J.A.16
Sampaio, C.17
Antonini, A.18
Stocchi, F.19
Montagna, P.20
Toni, V.21
Guidi, M.22
Dalla Libera, A.23
Tinazzi, M.24
De Pandis, F.25
Fabbrini, G.26
Goldwurm, S.27
De Klein, A.28
Barbosa, E.29
Lopiano, L.30
Martignoni, E.31
Lamberti, P.32
Vanacore, N.33
Meco, G.34
Oostra, B.A.35
more..
-
19
-
-
0033028516
-
Mitochondrial involvement in Alzheimer's disease
-
Bonilla E, Tanji K, Hirano M, Vu TH, DiMauro S, Schon EA (1999) Mitochondrial involvement in Alzheimer's disease. Biochim Biophys Acta 1410: 171-182.
-
(1999)
Biochim Biophys Acta
, vol.1410
, pp. 171-182
-
-
Bonilla, E.1
Tanji, K.2
Hirano, M.3
Vu, T.H.4
DiMauro, S.5
Schon, E.A.6
-
20
-
-
0030066069
-
Mitochondrial DNA sequence analysis of four Alzheimer's and Parkinson's disease patients
-
Brown MD, Shoffner JM, Kim YL, Jun AS, Graham BH, Cabell MF, Gurley DS, Wallace DC (1996) Mitochondrial DNA sequence analysis of four Alzheimer's and Parkinson's disease patients. Am J Med Genet 61: 283-289.
-
(1996)
Am J Med Genet
, vol.61
, pp. 283-289
-
-
Brown, M.D.1
Shoffner, J.M.2
Kim, Y.L.3
Jun, A.S.4
Graham, B.H.5
Cabell, M.F.6
Gurley, D.S.7
Wallace, D.C.8
-
21
-
-
0034904756
-
Novel mtDNA mutations and oxidative phosphorylation dysfunction in Russian LHON families
-
Brown MD, Zhadanov S, Allen JC, Hosseini S, Newman NJ, Atamonov VV, Mikhailovskaya IE, Sukernik RI, Wallace DC (2001) Novel mtDNA mutations and oxidative phosphorylation dysfunction in Russian LHON families. Hum Genet 109: 33-39.
-
(2001)
Hum Genet
, vol.109
, pp. 33-39
-
-
Brown, M.D.1
Zhadanov, S.2
Allen, J.C.3
Hosseini, S.4
Newman, N.J.5
Atamonov, V.V.6
Mikhailovskaya, I.E.7
Sukernik, R.I.8
Wallace, D.C.9
-
22
-
-
0036487995
-
The role of mtDNA background in disease expression: A new primary LHON mutation associated with Western Eurasian haplogroup J
-
Brown MD, Starikovskaya E, Derbeneva O, Hosseini S, Allen JC, Mikhailovskaya IE, Sukernik RI, Wallace DC (2002) The role of mtDNA background in disease expression: a new primary LHON mutation associated with Western Eurasian haplogroup J. Hum Genet 110: 130-138.
-
(2002)
Hum Genet
, vol.110
, pp. 130-138
-
-
Brown, M.D.1
Starikovskaya, E.2
Derbeneva, O.3
Hosseini, S.4
Allen, J.C.5
Mikhailovskaya, I.E.6
Sukernik, R.I.7
Wallace, D.C.8
-
23
-
-
0036745084
-
Does mitochondrial respiratory chain dysfunction have a role in common neurodegenerative disorders?
-
Byrne E (2002) Does mitochondrial respiratory chain dysfunction have a role in common neurodegenerative disorders? J Clin Neurosci 9: 497-501.
-
(2002)
J Clin Neurosci
, vol.9
, pp. 497-501
-
-
Byrne, E.1
-
24
-
-
24744442376
-
Mitochondrial DNA G10398A polymorphism and invasive breast cancer in African-American women
-
Canter JA, Kallianpur AR, Parl FF, Millikan RC (2005) Mitochondrial DNA G10398A polymorphism and invasive breast cancer in African-American women. Cancer Res 65: 8028-8033.
-
(2005)
Cancer Res
, vol.65
, pp. 8028-8033
-
-
Canter, J.A.1
Kallianpur, A.R.2
Parl, F.F.3
Millikan, R.C.4
-
25
-
-
25144514232
-
Somatic mitochondrial DNA mutations in single neurons and glia
-
Cantuti-Castelvetri I, Lin MT, Zheng K, Keller-McGandy CE, Betensky RA, Johns DR, Beal MF, Standaert DG, Simon DK (2005) Somatic mitochondrial DNA mutations in single neurons and glia. Neurobiol Aging 26: 1343-1355.
-
(2005)
Neurobiol Aging
, vol.26
, pp. 1343-1355
-
-
Cantuti-Castelvetri, I.1
Lin, M.T.2
Zheng, K.3
Keller-McGandy, C.E.4
Betensky, R.A.5
Johns, D.R.6
Beal, M.F.7
Standaert, D.G.8
Simon, D.K.9
-
26
-
-
17744397107
-
Mitochondrial DNA haplogroups and APOE4 allele are non-independent variables in sporadic Alzheimer's disease
-
Carrieri G, Bonafe M, De Luca M, Rose G, Varcasia O, Bruni A, Maletta R, Nacmias B, Sorbi S, Corsonello F, Feraco E, Andreev KF, Yashin AI, Franceschi C, De Benedictis G (2001) Mitochondrial DNA haplogroups and APOE4 allele are non-independent variables in sporadic Alzheimer's disease. Hum Genet 108: 194-198.
-
(2001)
Hum Genet
, vol.108
, pp. 194-198
-
-
Carrieri, G.1
Bonafe, M.2
De Luca, M.3
Rose, G.4
Varcasia, O.5
Bruni, A.6
Maletta, R.7
Nacmias, B.8
Sorbi, S.9
Corsonello, F.10
Feraco, E.11
Andreev, K.F.12
Yashin, A.I.13
Franceschi, C.14
De Benedictis, G.15
-
27
-
-
0036788005
-
Is Alzheimer's disease a mitochondrial disorder?
-
Cash AD, Perry G, Ogawa O, Raina AK, Zhu X, Smith MA (2002) Is Alzheimer's disease a mitochondrial disorder? Neuroscientist 8: 489-496.
-
(2002)
Neuroscientist
, vol.8
, pp. 489-496
-
-
Cash, A.D.1
Perry, G.2
Ogawa, O.3
Raina, A.K.4
Zhu, X.5
Smith, M.A.6
-
28
-
-
0036272650
-
Beta-amyloid inhibits integrated mitochondrial respiration and key enzyme activities
-
Casley CS, Canevari L, Land JM, Clark JB, Sharpe MA (2002) Beta-amyloid inhibits integrated mitochondrial respiration and key enzyme activities. J Neurochem 80: 91-100.
-
(2002)
J Neurochem
, vol.80
, pp. 91-100
-
-
Casley, C.S.1
Canevari, L.2
Land, J.M.3
Clark, J.B.4
Sharpe, M.A.5
-
30
-
-
0035125774
-
Point mutations of the mtDNA control region in normal and neurodegenerative human brains
-
Chinnery PF, Taylor GA, Howell N, Brown DT, Parsons TJ, Turnbull DM (2001) point mutations of the mtDNA control region in normal and neurodegenerative human brains. Am J Hum Genet 68(2): 529-532.
-
(2001)
Am J Hum Genet
, vol.68
, Issue.2
, pp. 529-532
-
-
Chinnery, P.F.1
Taylor, G.A.2
Howell, N.3
Brown, D.T.4
Parsons, T.J.5
Turnbull, D.M.6
-
32
-
-
0034025849
-
The biology of mitochondrial disease
-
Clarke A (2000) The biology of mitochondrial disease. Arch Dis Child 82: 339-340.
-
(2000)
Arch Dis Child
, vol.82
, pp. 339-340
-
-
Clarke, A.1
-
33
-
-
0030803457
-
Mitochondrial dysfunction in neurodegeneration
-
Cooper JM, Schapira AH (1997) Mitochondrial dysfunction in neurodegeneration. J Bioenerg Biomembr 29: 175-183.
-
(1997)
J Bioenerg Biomembr
, vol.29
, pp. 175-183
-
-
Cooper, J.M.1
Schapira, A.H.2
-
34
-
-
0037418174
-
Control region mtDNA variants: Longevity, climatic adaptation, and a forensic conundrum
-
U S A
-
Coskun PE, Ruiz-Pesini E, Wallace DC (2003) Control region mtDNA variants: Longevity, climatic adaptation, and a forensic conundrum. Proc Natl Acad Sci U S A 100: 2174-2176.
-
(2003)
Proc Natl Acad Sci
, vol.100
, pp. 2174-2176
-
-
Coskun, P.E.1
Ruiz-Pesini, E.2
Wallace, D.C.3
-
35
-
-
3242668604
-
Alzheimer's brains harbor somatic mtDNA control-region mutations that suppress mitochondrial transcription and replication
-
U S A
-
Coskun PE, Beal MF, Wallace DC (2004) Alzheimer's brains harbor somatic mtDNA control-region mutations that suppress mitochondrial transcription and replication. Proc Natl Acad Sci U S A 101: 10726-10731.
-
(2004)
Proc Natl Acad Sci
, vol.101
, pp. 10726-10731
-
-
Coskun, P.E.1
Beal, M.F.2
Wallace, D.C.3
-
36
-
-
19944433571
-
Copper-dependent inhibition of human cytochrome c oxidase by a dimeric conformer of amyloid-beta1-42
-
Crouch PJ, Blake R, Duce JA, Ciccotosto GD, Li QX, Barnham KJ, Curtain CC, Cherny RA, Cappai R, Dyrks T, Masters CL, Trounce IA (2005) Copper-dependent inhibition of human cytochrome c oxidase by a dimeric conformer of amyloid-beta1-42. J Neurosci 25: 672-679.
-
(2005)
J Neurosci
, vol.25
, pp. 672-679
-
-
Crouch, P.J.1
Blake, R.2
Duce, J.A.3
Ciccotosto, G.D.4
Li, Q.X.5
Barnham, K.J.6
Curtain, C.C.7
Cherny, R.A.8
Cappai, R.9
Dyrks, T.10
Masters, C.L.11
Trounce, I.A.12
-
37
-
-
10044270764
-
Association of the mitochondrial DNA haplogroup J with longevity is population specific
-
Dato S, Passarino G, Rose G, Altomare K, Bellizzi D, Mari V, Feraco E, Franceschi C, De Benedictis G (2004) Association of the mitochondrial DNA haplogroup J with longevity is population specific. Eur J Hum Genet 12: 1080-1082.
-
(2004)
Eur J Hum Genet
, vol.12
, pp. 1080-1082
-
-
Dato, S.1
Passarino, G.2
Rose, G.3
Altomare, K.4
Bellizzi, D.5
Mari, V.6
Feraco, E.7
Franceschi, C.8
De Benedictis, G.9
-
38
-
-
0242363670
-
Molecular pathways of neurodegeneration in Parkinson's disease
-
Dawson TM, Dawson VL (2003) Molecular pathways of neurodegeneration in Parkinson's disease. Science 302: 819-822.
-
(2003)
Science
, vol.302
, pp. 819-822
-
-
Dawson, T.M.1
Dawson, V.L.2
-
39
-
-
0032851615
-
Mitochondrial DNA inherited variants are associated with successful aging and longevity in humans
-
De Benedictis G, Rose G, Carrieri G, De Luca M, Falcone E, Passarino G, Bonafe M, Monti D, Baggio G, Bertolini S, Mari D, Mattace R, Franceschi C (1999) Mitochondrial DNA inherited variants are associated with successful aging and longevity in humans. Faseb J 13: 1532-1536.
-
(1999)
Faseb J
, vol.13
, pp. 1532-1536
-
-
De Benedictis, G.1
Rose, G.2
Carrieri, G.3
De Luca, M.4
Falcone, E.5
Passarino, G.6
Bonafe, M.7
Monti, D.8
Baggio, G.9
Bertolini, S.10
Mari, D.11
Mattace, R.12
Franceschi, C.13
-
40
-
-
0035880002
-
Recent advances in human gene-longevity association studies
-
De Benedictis G, Tan Q, Jeune B, Christensen K, Ukraintseva SV, Bonafe M, Franceschi C, Vaupel JW, Yashin AI (2001) Recent advances in human gene-longevity association studies. Mech Ageing Dev 122: 909-920.
-
(2001)
Mech Ageing Dev
, vol.122
, pp. 909-920
-
-
De Benedictis, G.1
Tan, Q.2
Jeune, B.3
Christensen, K.4
Ukraintseva, S.V.5
Bonafe, M.6
Franceschi, C.7
Vaupel, J.W.8
Yashin, A.I.9
-
41
-
-
33746395788
-
Dopamine: Not just a neurotransmitter
-
Drozak J, Bryla J (2005) Dopamine: not just a neurotransmitter (in Polish). Postepy Hig Med Dosw 59: 405-420.
-
(2005)
Postepy Hig Med Dosw
, vol.59
, pp. 405-420
-
-
Drozak, J.1
Bryla, J.2
-
42
-
-
4043086952
-
Mitochondria in health and disease: Perspectives on a new mitochondrial biology
-
Duchen MR (2004) Mitochondria in health and disease: perspectives on a new mitochondrial biology. Mol Aspects Med 25: 365-451.
-
(2004)
Mol Aspects Med
, vol.25
, pp. 365-451
-
-
Duchen, M.R.1
-
43
-
-
0036221421
-
Mitochondrial genetic variants and Alzheimer disease: A case-control study of the T4336C and G5460A variants
-
Edland SD, Tobe VO, Rieder MJ, Bowen JD, McCoemick W, Teri L, Schellenberg GD, Larson EB, Nickerson DA, Kukull WA (2002) Mitochondrial genetic variants and Alzheimer disease: A case-control study of the T4336C and G5460A variants. Alzheimer Dis Assoc Disord 16: 1-7.
-
(2002)
Alzheimer Dis Assoc Disord
, vol.16
, pp. 1-7
-
-
Edland, S.D.1
Tobe, V.O.2
Rieder, M.J.3
Bowen, J.D.4
McCoemick, W.5
Teri, L.6
Schellenberg, G.D.7
Larson, E.B.8
Nickerson, D.A.9
Kukull, W.A.10
-
44
-
-
0030811838
-
Association of the mitochondrial tRNA(A4336G) mutation with Alzheimer's and Parkinson's diseases
-
Egensperger R, Kosel S, Schnopp NM, Mehraein P, Graeber MB (1997) Association of the mitochondrial tRNA(A4336G) mutation with Alzheimer's and Parkinson's diseases. Neuropathol Appl Neurobiol 23: 315-321.
-
(1997)
Neuropathol Appl Neurobiol
, vol.23
, pp. 315-321
-
-
Egensperger, R.1
Kosel, S.2
Schnopp, N.M.3
Mehraein, P.4
Graeber, M.B.5
-
45
-
-
27644578107
-
Mitochondrial lipid abnormality and electron transport chain impairment in mice lacking alpha-synuclein
-
Ellis CE, Murphy EJ, Mitchell DC, Golovko MY, Scaglia F, Barcelo-Coblijn GC, Nussbaum RL (2005) Mitochondrial lipid abnormality and electron transport chain impairment in mice lacking alpha-synuclein. Mol Cell Biol 25: 10190-10201.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 10190-10201
-
-
Ellis, C.E.1
Murphy, E.J.2
Mitchell, D.C.3
Golovko, M.Y.4
Scaglia, F.5
Barcelo-Coblijn, G.C.6
Nussbaum, R.L.7
-
47
-
-
0142121353
-
The contribution of mitochondria to common disorders
-
Enns GM (2003) The contribution of mitochondria to common disorders. Mol Genet Metab 80: 11-26.
-
(2003)
Mol Genet Metab
, vol.80
, pp. 11-26
-
-
Enns, G.M.1
-
49
-
-
33645116252
-
Genetics of Parkinson disease: Paradigm shifts and future prospects
-
Farrer MJ (2006) Genetics of Parkinson disease: paradigm shifts and future prospects. Nat Rev Genet 7: 306-318.
-
(2006)
Nat Rev Genet
, vol.7
, pp. 306-318
-
-
Farrer, M.J.1
-
50
-
-
0035081109
-
Phylogenetic analysis of mtDNA haplogroup TJ in a Finnish population
-
Finnila S, Majamaa K (2001) Phylogenetic analysis of mtDNA haplogroup TJ in a Finnish population. J Hum Genet 46: 64-69.
-
(2001)
J Hum Genet
, vol.46
, pp. 64-69
-
-
Finnila, S.1
Majamaa, K.2
-
52
-
-
3342978711
-
Enzyme histochemical studies of senile plaques
-
Friede RI (1965) Enzyme histochemical studies of senile plaques. J Neuropathol Exp Neurol 24: 477-491.
-
(1965)
J Neuropathol Exp Neurol
, vol.24
, pp. 477-491
-
-
Friede, R.I.1
-
53
-
-
0037417220
-
Apoptosis and caspases in neurodegenerative diseases
-
Friedlander RM (2003) Apoptosis and caspases in neurodegenerative diseases. N Engl J Med 348: 1365-1375.
-
(2003)
N Engl J Med
, vol.348
, pp. 1365-1375
-
-
Friedlander, R.M.1
-
54
-
-
0028078692
-
Altered cerebral energy metabolism in Alzheimer's disease: A PET study
-
Fukuyama H, Ogawa M, Yamauchi H, Yamaguchi S, Kimura J, Yonekura Y, Konishi J (1994) Altered cerebral energy metabolism in Alzheimer's disease: A PET study. J Nucl Med 35: 1-6.
-
(1994)
J Nucl Med
, vol.35
, pp. 1-6
-
-
Fukuyama, H.1
Ogawa, M.2
Yamauchi, H.3
Yamaguchi, S.4
Kimura, J.5
Yonekura, Y.6
Konishi, J.7
-
55
-
-
0036048612
-
Mitochondrial DNAA4336G mutation in Alzheimer's and Parkinson's diseases
-
Garcia-Lozano JR, Mir P, Alberca R, Aguilera I, Gil Neciga E, Fernandez-Lopez O, Cayuela A, Nunez-Roldan A (2002) Mitochondrial DNAA4336G mutation in Alzheimer's and Parkinson's diseases. Eur Neurol 48: 34-36.
-
(2002)
Eur Neurol
, vol.48
, pp. 34-36
-
-
Garcia-Lozano, J.R.1
Mir, P.2
Alberca, R.3
Aguilera, I.4
Gil Neciga, E.5
Fernandez-Lopez, O.6
Cayuela, A.7
Nunez-Roldan, A.8
-
56
-
-
20544461885
-
Mitochondrial DNA haplogroup K is associated with a lower risk of Parkinson's disease in Italians
-
Ghezzi D, Marelli C, Achilli A, Goldwurm S, Pezzoli G, Barone P, Pellecchia MT, Stanzione P, Brusa L, Bentivoglio AR, Bonuccelli U, Petrozzi L, Abbruzzese G, Marchese R, Cortelli P, Grimaldi D, Martinelli P, Ferrarese C, Garavaglia B, Sangiorgi S, Carelli V, Torroni A, Albanese A, Zeviani M (2005) Mitochondrial DNA haplogroup K is associated with a lower risk of Parkinson's disease in Italians. Eur J Hum Genet 13: 748-752.
-
(2005)
Eur J Hum Genet
, vol.13
, pp. 748-752
-
-
Ghezzi, D.1
Marelli, C.2
Achilli, A.3
Goldwurm, S.4
Pezzoli, G.5
Barone, P.6
Pellecchia, M.T.7
Stanzione, P.8
Brusa, L.9
Bentivoglio, A.R.10
Bonuccelli, U.11
Petrozzi, L.12
Abbruzzese, G.13
Marchese, R.14
Cortelli, P.15
Grimaldi, D.16
Martinelli, P.17
Ferrarese, C.18
Garavaglia, B.19
Sangiorgi, S.20
Carelli, V.21
Torroni, A.22
Albanese, A.23
Zeviani, M.24
more..
-
57
-
-
0034602442
-
Oxidative damage linked to neurodegeneration by selective alpha-synuclein nitration in synucleinopathy lesions
-
Giasson BI, Duda JE, Murray IV, Chen Q, Souza JM, Hurtig HI, Ischiropoulos H, Trojanowski JQ, Lee VM (2000) Oxidative damage linked to neurodegeneration by selective alpha-synuclein nitration in synucleinopathy lesions. Science 290: 985-989.
-
(2000)
Science
, vol.290
, pp. 985-989
-
-
Giasson, B.I.1
Duda, J.E.2
Murray, I.V.3
Chen, Q.4
Souza, J.M.5
Hurtig, H.I.6
Ischiropoulos, H.7
Trojanowski, J.Q.8
Lee, V.M.9
-
58
-
-
0037096193
-
The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer's and Parkinson's diseases
-
Giasson BI, Ischiropoulos H, Lee VM, Trojanowski JQ (2002) The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer's and Parkinson's diseases. Free Radic Biol Med 32: 1264-1275.
-
(2002)
Free Radic Biol Med
, vol.32
, pp. 1264-1275
-
-
Giasson, B.I.1
Ischiropoulos, H.2
Lee, V.M.3
Trojanowski, J.Q.4
-
59
-
-
0031737226
-
Abnormalities of mitochondrial enzymes in Alzheimer disease
-
Gibson GE, Sheu KF, Blass JP (1998) Abnormalities of mitochondrial enzymes in Alzheimer disease. J Neural Transm 105: 855-870.
-
(1998)
J Neural Transm
, vol.105
, pp. 855-870
-
-
Gibson, G.E.1
Sheu, K.F.2
Blass, J.P.3
-
60
-
-
2442636348
-
Biomedicine. Parkinson's - Divergent causes, convergent mechanisms
-
Greenamyre JT, Hastings TG (2004) Biomedicine. Parkinson's - divergent causes, convergent mechanisms. Science 304: 1120-1122.
-
(2004)
Science
, vol.304
, pp. 1120-1122
-
-
Greenamyre, J.T.1
Hastings, T.G.2
-
61
-
-
0037386532
-
Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants
-
U S A
-
Greene JC, Whitworth AJ, Kuo I, Andrews LA, Feany MB, Pallanck LJ (2003) Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants. Proc Natl Acad Sci U S A 100: 4078-4083.
-
(2003)
Proc Natl Acad Sci
, vol.100
, pp. 4078-4083
-
-
Greene, J.C.1
Whitworth, A.J.2
Kuo, I.3
Andrews, L.A.4
Feany, M.B.5
Pallanck, L.J.6
-
62
-
-
0031859395
-
Mitochondrial DNA transmission of the mitochondrial defect in Parkinson's disease
-
Gu M, Cooper JM, Taanman JW, Schapira AH (1998) Mitochondrial DNA transmission of the mitochondrial defect in Parkinson's disease. Ann Neurol 44: 177-186.
-
(1998)
Ann Neurol
, vol.44
, pp. 177-186
-
-
Gu, M.1
Cooper, J.M.2
Taanman, J.W.3
Schapira, A.H.4
-
63
-
-
0031052381
-
Amyloid, the presenilins and Alzheimer's disease
-
Hardy J (1997) Amyloid, the presenilins and Alzheimer's disease. Trends Neurosci 20: 154-159.
-
(1997)
Trends Neurosci
, vol.20
, pp. 154-159
-
-
Hardy, J.1
-
64
-
-
0015319592
-
The biologic clock: The mitochondria?
-
Harman D (1972) The biologic clock: The mitochondria? J Am Geriatr Soc 20: 145-147.
-
(1972)
J Am Geriatr Soc
, vol.20
, pp. 145-147
-
-
Harman, D.1
-
65
-
-
0031771518
-
Interaction of alpha-phenyl-N-tert-butyl nitrone and alternative electron acceptors with complex I indicates a substrate reduction site upstream from the rotenone binding site
-
Hensley K, Pye QN, Maidt ML, Stewart CA, Robinson KA, Jaffrey F, Floyd RA (1998) Interaction of alpha-phenyl-N-tert-butyl nitrone and alternative electron acceptors with complex I indicates a substrate reduction site upstream from the rotenone binding site. J Neurochem 71:2549-2557.
-
(1998)
J Neurochem
, vol.71
, pp. 2549-2557
-
-
Hensley, K.1
Pye, Q.N.2
Maidt, M.L.3
Stewart, C.A.4
Robinson, K.A.5
Jaffrey, F.6
Floyd, R.A.7
-
66
-
-
18344366125
-
Reduced-median-network analysis of complete mitochondrial DNA coding-region sequences for the major African, Asian, and European haplogroups
-
Herrnstadt C, Elson JL, Fahy E, Preston G, Turnbull DM, Anderson C, Ghosh SS, Olefsky JM, Beal MF, Davis RE, Howell N (2002) Reduced-median-network analysis of complete mitochondrial DNA coding-region sequences for the major African, Asian, and European haplogroups. Am J Hum Genet 70: 1152-1171.
-
(2002)
Am J Hum Genet
, vol.70
, pp. 1152-1171
-
-
Herrnstadt, C.1
Elson, J.L.2
Fahy, E.3
Preston, G.4
Turnbull, D.M.5
Anderson, C.6
Ghosh, S.S.7
Olefsky, J.M.8
Beal, M.F.9
Davis, R.E.10
Howell, N.11
-
67
-
-
0030813676
-
Population genetics and disease susceptibility: Characterization of central European haplogroups by mtDNA gene mutations, correlation with D loop variants and association with disease
-
Hofmann S, Jaksch M, Bezold R, Mertens S, Aholt S, Paprotta A, Gerbitz KD (1997) Population genetics and disease susceptibility: Characterization of central European haplogroups by mtDNA gene mutations, correlation with D loop variants and association with disease. Hum Mol Genet 6: 1835-1846.
-
(1997)
Hum Mol Genet
, vol.6
, pp. 1835-1846
-
-
Hofmann, S.1
Jaksch, M.2
Bezold, R.3
Mertens, S.4
Aholt, S.5
Paprotta, A.6
Gerbitz, K.D.7
-
68
-
-
0035012777
-
High incidence of single nucleotide substitutions in the mitochondrial genome is associated with poor semen parameters in men
-
Holyoake AJ, McHugh P, Wu M, O'Carroll S, Benny P, Sin IL, Sin FY (2001) High incidence of single nucleotide substitutions in the mitochondrial genome is associated with poor semen parameters in men. Int J Androl 24: 175-182.
-
(2001)
Int J Androl
, vol.24
, pp. 175-182
-
-
Holyoake, A.J.1
McHugh, P.2
Wu, M.3
O'Carroll, S.4
Benny, P.5
Sin, I.L.6
Sin, F.Y.7
-
70
-
-
24044555258
-
Mitochondrial DNA polymorphisms and risk of Parkinson's disease in Spanish population
-
Huerta C, Castro MG, Coto E, Blazquez M, Ribacoba R, Guisasola LM, Salvador C, Martinez C, Lahoz CH, Alvarez V (2005) Mitochondrial DNA polymorphisms and risk of Parkinson's disease in Spanish population. J Neurol Sci 236: 49-54.
-
(2005)
J Neurol Sci
, vol.236
, pp. 49-54
-
-
Huerta, C.1
Castro, M.G.2
Coto, E.3
Blazquez, M.4
Ribacoba, R.5
Guisasola, L.M.6
Salvador, C.7
Martinez, C.8
Lahoz, C.H.9
Alvarez, V.10
-
71
-
-
0029396761
-
The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part IX. A prospective cliniconeuropathologic study of Parkinson's features in Alzheimer's disease
-
Hulette C, Mirra S, Wilkinson W, Heyman A, Fillenbaum G, Clark C (1995) The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part IX. A prospective cliniconeuropathologic study of Parkinson's features in Alzheimer's disease. Neurology 45: 1991-1995.
-
(1995)
Neurology
, vol.45
, pp. 1991-1995
-
-
Hulette, C.1
Mirra, S.2
Wilkinson, W.3
Heyman, A.4
Fillenbaum, G.5
Clark, C.6
-
72
-
-
0029091194
-
A mitochondrial DNA clone is associated with increased risk for Alzheimer disease
-
U S A
-
Hutchin T, Cortopassi G (1995) A mitochondrial DNA clone is associated with increased risk for Alzheimer disease. Proc Natl Acad Sci U S A 92: 6892-6895.
-
(1995)
Proc Natl Acad Sci
, vol.92
, pp. 6892-6895
-
-
Hutchin, T.1
Cortopassi, G.2
-
73
-
-
0031796015
-
Mitochondrial genotype associated with French Caucasian centenarians
-
Ivanova R, Lepage V, Charron D, Schachter F (1998) Mitochondrial genotype associated with French Caucasian centenarians. Gerontology 44: 349.
-
(1998)
Gerontology
, vol.44
, pp. 349
-
-
Ivanova, R.1
Lepage, V.2
Charron, D.3
Schachter, F.4
-
74
-
-
0026036025
-
Alternative, simultaneous complex I mitochondrial DNA mutations in Leber's hereditary optic neuropathy
-
Johns DR, Berman J (1991) Alternative, simultaneous complex I mitochondrial DNA mutations in Leber's hereditary optic neuropathy. Biochem Biophys Res Commun 174: 1324-1330.
-
(1991)
Biochem Biophys Res Commun
, vol.174
, pp. 1324-1330
-
-
Johns, D.R.1
Berman, J.2
-
75
-
-
2342429459
-
DNA polymerase gamma, the mitochondrial replicase
-
Kaguni LS (2004) DNA polymerase gamma, the mitochondrial replicase. Annu Rev Biochem 73: 293-320.
-
(2004)
Annu Rev Biochem
, vol.73
, pp. 293-320
-
-
Kaguni, L.S.1
-
76
-
-
14644422657
-
Alterations of mitochondrial DNA in common diseases and disease states: Aging, neurodegeneration, heart failure, diabetes, and cancer
-
Kang D, Hamasaki N (2005) Alterations of mitochondrial DNA in common diseases and disease states: Aging, neurodegeneration, heart failure, diabetes, and cancer. Curr Med Chem 12: 429-441.
-
(2005)
Curr Med Chem
, vol.12
, pp. 429-441
-
-
Kang, D.1
Hamasaki, N.2
-
77
-
-
0033794686
-
Mitochondrial ND1 sequence analysis and association of the T4216C mutation with Parkinson's disease
-
Kirchner SC, Hallagan SE, Farin FM, Dilley J, Costa-Mallen P, Smith-Weller T, Franklin GM, Swanson PD, Checkoway H (2000) Mitochondrial ND1 sequence analysis and association of the T4216C mutation with Parkinson's disease. Neurotoxicology 21: 441-445.
-
(2000)
Neurotoxicology
, vol.21
, pp. 441-445
-
-
Kirchner, S.C.1
Hallagan, S.E.2
Farin, F.M.3
Dilley, J.4
Costa-Mallen, P.5
Smith-Weller, T.6
Franklin, G.M.7
Swanson, P.D.8
Checkoway, H.9
-
78
-
-
27244432742
-
PINK1, Parkin, and DJ-1 mutations in Italian patients with early-onset parkinsonism
-
Klein C, Djarmati A, Hedrich K, Schafer N, Scaglione C, Marchese R, Kock N, Schule B, Hiller A, Lohnau T, Winkler S, Wiegers K, Hering R, Bauer P, Riess O, Abbruzzese G, Martinelli P, Pramstaller PP (2005) PINK1, Parkin, and DJ-1 mutations in Italian patients with early-onset parkinsonism. Eur J Hum Genet 13: 1086-1093.
-
(2005)
Eur J Hum Genet
, vol.13
, pp. 1086-1093
-
-
Klein, C.1
Djarmati, A.2
Hedrich, K.3
Schafer, N.4
Scaglione, C.5
Marchese, R.6
Kock, N.7
Schule, B.8
Hiller, A.9
Lohnau, T.10
Winkler, S.11
Wiegers, K.12
Hering, R.13
Bauer, P.14
Riess, O.15
Abbruzzese, G.16
Martinelli, P.17
Pramstaller, P.P.18
-
79
-
-
33244460534
-
Mice lacking alpha-synuclein are resistant to mitochondrial toxins
-
Klivenyi P, Siwek D, Gardian G, Yang L, Starkov A, Cleren C, Ferrante RJ, Kowall NW, Abeliovich A, Beal MF (2006) Mice lacking alpha-synuclein are resistant to mitochondrial toxins. Neurobiol Dis 21: 541-548.
-
(2006)
Neurobiol Dis
, vol.21
, pp. 541-548
-
-
Klivenyi, P.1
Siwek, D.2
Gardian, G.3
Yang, L.4
Starkov, A.5
Cleren, C.6
Ferrante, R.J.7
Kowall, N.W.8
Abeliovich, A.9
Beal, M.F.10
-
80
-
-
0042387705
-
Phylogeny of east Asian mitochondrial DNA lineages inferred from complete sequences
-
Kong QP, Yao YG, Sun C, Bandelt HJ, Zhu CL, Zhang YP (2003) Phylogeny of east Asian mitochondrial DNA lineages inferred from complete sequences. Am J Hum Genet 73: 671-676.
-
(2003)
Am J Hum Genet
, vol.73
, pp. 671-676
-
-
Kong, Q.P.1
Yao, Y.G.2
Sun, C.3
Bandelt, H.J.4
Zhu, C.L.5
Zhang, Y.P.6
-
81
-
-
8844254726
-
Apolipoprotein Abeta: Black sheep in a good family
-
Kontush A (2004) Apolipoprotein Abeta: Black sheep in a good family. Brain Pathol 14: 433-447.
-
(2004)
Brain Pathol
, vol.14
, pp. 433-447
-
-
Kontush, A.1
-
82
-
-
1842555337
-
Alzheimer's amyloid-beta (A beta) is an essential synaptic protein, not neurotoxic junk
-
Koudinov AR, Berezov TT (2004) Alzheimer's amyloid-beta (A beta) is an essential synaptic protein, not neurotoxic junk. Acta Neurobiol Exp (Wars) 64: 71-79.
-
(2004)
Acta Neurobiol Exp (Wars)
, vol.64
, pp. 71-79
-
-
Koudinov, A.R.1
Berezov, T.T.2
-
83
-
-
25844476202
-
Early environmental origins of neurodegenerative disease in later life
-
Landrigan PJ, Sonawane B, Butler RN, Trasande L, Callan R, Droller D (2005) Early environmental origins of neurodegenerative disease in later life. Environ Health Perspect 113: 1230-1233.
-
(2005)
Environ Health Perspect
, vol.113
, pp. 1230-1233
-
-
Landrigan, P.J.1
Sonawane, B.2
Butler, R.N.3
Trasande, L.4
Callan, R.5
Droller, D.6
-
84
-
-
0032829070
-
Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure
-
Langston JW, Forno LS, Tetrud J, Reeves AG, Kaplan JA, Karluk D (1999) Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure. Ann Neurol 46: 598-605.
-
(1999)
Ann Neurol
, vol.46
, pp. 598-605
-
-
Langston, J.W.1
Forno, L.S.2
Tetrud, J.3
Reeves, A.G.4
Kaplan, J.A.5
Karluk, D.6
-
85
-
-
0033964762
-
Mitochondrial role in life and death of the cell
-
Lee HC, Wei YH (2000) Mitochondrial role in life and death of the cell. J Biomed Sci 7: 2-15.
-
(2000)
J Biomed Sci
, vol.7
, pp. 2-15
-
-
Lee, H.C.1
Wei, Y.H.2
-
86
-
-
17044435830
-
Tau phosphorylation in Alzheimer's disease: Pathogen or protector?
-
Lee HG, Perry G, Moreira PI, Garett MR, Liu Q, Zhu X, Takeda A, Nunomura A, Smith MA (2005) Tau phosphorylation in Alzheimer's disease: Pathogen or protector? Trends Mol Med 11(4): 164-169.
-
(2005)
Trends Mol Med
, vol.11
, Issue.4
, pp. 164-169
-
-
Lee, H.G.1
Perry, G.2
Moreira, P.I.3
Garett, M.R.4
Liu, Q.5
Zhu, X.6
Takeda, A.7
Nunomura, A.8
Smith, M.A.9
-
87
-
-
0037081814
-
High aggregate burden of somatic mtDNA point mutations in aging and Alzheimer's disease brain
-
Lin MT, Simon DK, Ahn CH, Kim LM, Beal MF (2002) High aggregate burden of somatic mtDNA point mutations in aging and Alzheimer's disease brain. Hum Mol Genet 11: 133-145.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 133-145
-
-
Lin, M.T.1
Simon, D.K.2
Ahn, C.H.3
Kim, L.M.4
Beal, M.F.5
-
88
-
-
0024541837
-
Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases
-
Linnane AW, Marzuki S, Ozawa T, Tanaka M (1989) Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases. Lancet 1: 642-645.
-
(1989)
Lancet
, vol.1
, pp. 642-645
-
-
Linnane, A.W.1
Marzuki, S.2
Ozawa, T.3
Tanaka, M.4
-
89
-
-
13844267510
-
Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations
-
Liu Q, Smith MA, Avila J, DeBernardis J, Kansal M, Takeda A, Zhu X, Nunomura A, Honda K, Moreira PI, Oliveira CR, Santos MS, Shimohama S, Aliev G, de la Torre J, Ghanbari HA, Siedlak SL, Harris PL, Sayre LM, Perry G (2005) Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations. Free Radic Biol Med 38: 746-754.
-
(2005)
Free Radic Biol Med
, vol.38
, pp. 746-754
-
-
Liu, Q.1
Smith, M.A.2
Avila, J.3
DeBernardis, J.4
Kansal, M.5
Takeda, A.6
Zhu, X.7
Nunomura, A.8
Honda, K.9
Moreira, P.I.10
Oliveira, C.R.11
Santos, M.S.12
Shimohama, S.13
Aliev, G.14
De La Torre, J.15
Ghanbari, H.A.16
Siedlak, S.L.17
Harris, P.L.18
Sayre, L.M.19
Perry, G.20
more..
-
91
-
-
11144353586
-
ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease
-
Lustbader JW, Cirilli M, Lin C, Xu HW, Takuma K, Wang N, Caspersen C, Chen X, Pollak S, Chaney M, Trinchese F, Liu S, Gunn-Moore F, Lue LF, Walker DG, Kuppusamy P, Zewier ZL, Arancio O, Stern D, Yan SS, Wu H (2004) ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease. Science 304: 448-452.
-
(2004)
Science
, vol.304
, pp. 448-452
-
-
Lustbader, J.W.1
Cirilli, M.2
Lin, C.3
Xu, H.W.4
Takuma, K.5
Wang, N.6
Caspersen, C.7
Chen, X.8
Pollak, S.9
Chaney, M.10
Trinchese, F.11
Liu, S.12
Gunn-Moore, F.13
Lue, L.F.14
Walker, D.G.15
Kuppusamy, P.16
Zewier, Z.L.17
Arancio, O.18
Stern, D.19
Yan, S.S.20
Wu, H.21
more..
-
92
-
-
0033937733
-
The role of mitochondria in the pathogenesis of neurodegenerative diseases
-
Manfredi G, Beal MF (2000) The role of mitochondria in the pathogenesis of neurodegenerative diseases. Brain Pathol 10: 462-472.
-
(2000)
Brain Pathol
, vol.10
, pp. 462-472
-
-
Manfredi, G.1
Beal, M.F.2
-
93
-
-
33644534495
-
From structural biochemistry to expression profiling: Neuroprotective activities of estrogen
-
Manthey D, Behl C (2006) From structural biochemistry to expression profiling: Neuroprotective activities of estrogen. Neuroscience 138: 845-850.
-
(2006)
Neuroscience
, vol.138
, pp. 845-850
-
-
Manthey, D.1
Behl, C.2
-
94
-
-
7644230386
-
Neuroprotective role of the Reaper-related serine protease HtrA2/Omi revealed by targeted deletion in mice
-
Martins LM, Morrison A, Klupsch K, Fedele V, Moisoi N, Teismann P, Abuin A, Grau E, Geppert M, Livi GP, Creasy CL, Martin A, Hargreaves I, Heales SJ, Okada H, Brandner S, Schulz JB, Mak T, Downward J (2004) Neuroprotective role of the Reaper-related serine protease HtrA2/Omi revealed by targeted deletion in mice. Mol Cell Biol 24: 9848-9862.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 9848-9862
-
-
Martins, L.M.1
Morrison, A.2
Klupsch, K.3
Fedele, V.4
Moisoi, N.5
Teismann, P.6
Abuin, A.7
Grau, E.8
Geppert, M.9
Livi, G.P.10
Creasy, C.L.11
Martin, A.12
Hargreaves, I.13
Heales, S.J.14
Okada, H.15
Brandner, S.16
Schulz, J.B.17
Mak, T.18
Downward, J.19
-
95
-
-
1242292303
-
Region-specific analysis of mitochondrial DNA deletions in neurodegenerative disorders in humans
-
Mawrin C, Kirches E, Krause G, Schneider-Stock R, Bogerts B, Vorwerk CK, Dietzmann K (2004) Region-specific analysis of mitochondrial DNA deletions in neurodegenerative disorders in humans. Neurosci Lett 357: 111-114.
-
(2004)
Neurosci Lett
, vol.357
, pp. 111-114
-
-
Mawrin, C.1
Kirches, E.2
Krause, G.3
Schneider-Stock, R.4
Bogerts, B.5
Vorwerk, C.K.6
Dietzmann, K.7
-
96
-
-
0028152717
-
Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease
-
Mecocci P, MacGarvey U, Beal MF (1994) Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease. Ann Neurol 36: 747-751.
-
(1994)
Ann Neurol
, vol.36
, pp. 747-751
-
-
Mecocci, P.1
MacGarvey, U.2
Beal, M.F.3
-
97
-
-
4544307465
-
Modeling mitochondrial function in aging neurons
-
Melov S (2004) Modeling mitochondrial function in aging neurons. Trends Neurosci 27: 601-606.
-
(2004)
Trends Neurosci
, vol.27
, pp. 601-606
-
-
Melov, S.1
-
98
-
-
13644270565
-
Oxidative DNA damage in peripheral leukocytes of mild cognitive impairment and AD patients
-
Migliore L, Fontana I, Trippi F, Colognato R, Coppede F, Tognoni G, Nucciarone B, Siciliano G (2005) Oxidative DNA damage in peripheral leukocytes of mild cognitive impairment and AD patients. Neurobiol Aging 26: 567-573.
-
(2005)
Neurobiol Aging
, vol.26
, pp. 567-573
-
-
Migliore, L.1
Fontana, I.2
Trippi, F.3
Colognato, R.4
Coppede, F.5
Tognoni, G.6
Nucciarone, B.7
Siciliano, G.8
-
99
-
-
0037422550
-
Natural selection shaped regional mtDNA variation in humans
-
U S A
-
Mishmar D, Ruiz-Pesini E, Golik P, Macaulay V, Clark AG, Hosseini S, Brandon M, Easley K, Chen E, Brown MD, Sukernik RI, Olckers A, Wallace DC (2003) Natural selection shaped regional mtDNA variation in humans. Proc Natl Acad Sci U S A 100: 171-176.
-
(2003)
Proc Natl Acad Sci
, vol.100
, pp. 171-176
-
-
Mishmar, D.1
Ruiz-Pesini, E.2
Golik, P.3
Macaulay, V.4
Clark, A.G.5
Hosseini, S.6
Brandon, M.7
Easley, K.8
Chen, E.9
Brown, M.D.10
Sukernik, R.I.11
Olckers, A.12
Wallace, D.C.13
-
100
-
-
0035692636
-
DJ-1 is an indicator for endogenous reactive oxygen species elicited by endotoxin
-
Mitsumoto A, Nakagawa Y (2001) DJ-1 is an indicator for endogenous reactive oxygen species elicited by endotoxin. Free Radic Res 35: 885-893.
-
(2001)
Free Radic Res
, vol.35
, pp. 885-893
-
-
Mitsumoto, A.1
Nakagawa, Y.2
-
101
-
-
0029765553
-
Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides
-
Miyata M, Smith JD (1996) Apolipoprotein E allele-specific antioxidant activity and effects on cytotoxicity by oxidative insults and beta-amyloid peptides. Nat Genet 14: 55-61.
-
(1996)
Nat Genet
, vol.14
, pp. 55-61
-
-
Miyata, M.1
Smith, J.D.2
-
102
-
-
33644526277
-
Estrogen, neuroinflammation and neuroprotection in Parkinson's disease: Glia dictates resistance versus vulnerability to neurodegeneration
-
Morale MC, Serra PA, L'Episcopo F, Tirolo C, Caniglia S, Testa N, Gennuso F, Giaquinta G, Rocchitta G, Desole MS, Miele E, Marchetti B (2006) Estrogen, neuroinflammation and neuroprotection in Parkinson's disease: Glia dictates resistance versus vulnerability to neurodegeneration. Neuroscience 138: 869-878.
-
(2006)
Neuroscience
, vol.138
, pp. 869-878
-
-
Morale, M.C.1
Serra, P.A.2
L'Episcopo, F.3
Tirolo, C.4
Caniglia, S.5
Testa, N.6
Gennuso, F.7
Giaquinta, G.8
Rocchitta, G.9
Desole, M.S.10
Miele, E.11
Marchetti, B.12
-
103
-
-
24644443839
-
Oxidative stress: The old enemy in Alzheimer's disease pathophysiology
-
Moreira PI, Honda K, Liu Q, Santos MS, Oliveira CR, Aliev G, Nunomura A, Zhu X, Smith MA, Perry G (2005) Oxidative stress: The old enemy in Alzheimer's disease pathophysiology. Curr Alzheimer Res 2: 403-408.
-
(2005)
Curr Alzheimer Res
, vol.2
, pp. 403-408
-
-
Moreira, P.I.1
Honda, K.2
Liu, Q.3
Santos, M.S.4
Oliveira, C.R.5
Aliev, G.6
Nunomura, A.7
Zhu, X.8
Smith, M.A.9
Perry, G.10
-
104
-
-
0141510019
-
Oxidative damage to mitochondrial complex I due to peroxynitrite: Identification of reactive tyrosines by mass spectrometry
-
Murray J, Taylor SW, Zhang B, Ghosh SS, Capaldi RA (2003) Oxidative damage to mitochondrial complex I due to peroxynitrite: Identification of reactive tyrosines by mass spectrometry. J Biol Chem 278: 37223-37230.
-
(2003)
J Biol Chem
, vol.278
, pp. 37223-37230
-
-
Murray, J.1
Taylor, S.W.2
Zhang, B.3
Ghosh, S.S.4
Capaldi, R.A.5
-
105
-
-
0035758117
-
Hunting genes in Parkinson's disease from the roots
-
Muthane U, Jain S, Gururaj G (2001) Hunting genes in Parkinson's disease from the roots. Med Hypotheses 57: 51-55.
-
(2001)
Med Hypotheses
, vol.57
, pp. 51-55
-
-
Muthane, U.1
Jain, S.2
Gururaj, G.3
-
106
-
-
0037117576
-
Clonally expanded mtDNA point mutations are abundant in individual cells of human tissues
-
U S A
-
Nekhaeva E, Bodyak ND, Kraytsberg Y, McGrath SB, Van Orsouw NJ, Pluzhnikov A, Wei JY, Vijg J, Khrapko K (2002) Clonally expanded mtDNA point mutations are abundant in individual cells of human tissues. Proc Natl Acad Sci U S A 99: 5521-5526.
-
(2002)
Proc Natl Acad Sci
, vol.99
, pp. 5521-5526
-
-
Nekhaeva, E.1
Bodyak, N.D.2
Kraytsberg, Y.3
McGrath, S.B.4
Van Orsouw, N.J.5
Pluzhnikov, A.6
Wei, J.Y.7
Vijg, J.8
Khrapko, K.9
-
107
-
-
0037209210
-
Mitochondrial DNA polymorphisms associated with longevity in a Finnish population
-
Niemi AK, Hervonen A, Hurme M, Karhunen PJ, Jylha M, Majamaa K (2003) Mitochondrial DNA polymorphisms associated with longevity in a Finnish population. Hum Genet 112: 29-33.
-
(2003)
Hum Genet
, vol.112
, pp. 29-33
-
-
Niemi, A.K.1
Hervonen, A.2
Hurme, M.3
Karhunen, P.J.4
Jylha, M.5
Majamaa, K.6
-
108
-
-
13544272017
-
A combination of three common inherited mitochondrial DNA polymorphisms promotes longevity in Finnish and Japanese subjects
-
Niemi AK, Moilanen JS, Tanaka M, Hervonen A, Hurme M, Lehtimaki T, Arai Y, Hirose N, Majamaa K (2005) A combination of three common inherited mitochondrial DNA polymorphisms promotes longevity in Finnish and Japanese subjects. Eur J Hum Genet 13: 166-170.
-
(2005)
Eur J Hum Genet
, vol.13
, pp. 166-170
-
-
Niemi, A.K.1
Moilanen, J.S.2
Tanaka, M.3
Hervonen, A.4
Hurme, M.5
Lehtimaki, T.6
Arai, Y.7
Hirose, N.8
Majamaa, K.9
-
109
-
-
0036834187
-
Amyloid-beta: A (life) preserver for the brain
-
Obrenovich ME, Joseph JA, Atwood CS, Perry G, Smith MA (2002) Amyloid-beta: A (life) preserver for the brain. Neurobiol Aging 23: 1097-1099.
-
(2002)
Neurobiol Aging
, vol.23
, pp. 1097-1099
-
-
Obrenovich, M.E.1
Joseph, J.A.2
Atwood, C.S.3
Perry, G.4
Smith, M.A.5
-
110
-
-
14644446028
-
Activation of p38 and N-acetylcysteine-sensitive c-Jun NH2-terminal kinase signaling cascades is required for induction of apoptosis in Parkinson's disease cybrids
-
Onyango IG, Tuttle JB, Bennett JP, Jr. (2005) Activation of p38 and N-acetylcysteine-sensitive c-Jun NH2-terminal kinase signaling cascades is required for induction of apoptosis in Parkinson's disease cybrids. Mol Cell Neurosci 28: 452-461.
-
(2005)
Mol Cell Neurosci
, vol.28
, pp. 452-461
-
-
Onyango, I.G.1
Tuttle, J.B.2
Bennett Jr., J.P.3
-
111
-
-
0036182026
-
Mitochondrial involvement in Parkinson's disease
-
Orth M, Schapira AH (2002) Mitochondrial involvement in Parkinson's disease. Neurochem Int 40: 533-541.
-
(2002)
Neurochem Int
, vol.40
, pp. 533-541
-
-
Orth, M.1
Schapira, A.H.2
-
112
-
-
5644243261
-
Mitochondrial polymporphisms in Parkinson's Disease
-
Otaegui D, Paisan C, Saenz A, Marti I, Ribate M, Marti-Masso JF, Perez-Tur J, Lopez de Munain A (2004) Mitochondrial polymporphisms in Parkinson's Disease. Neurosci Lett 370: 171-174.
-
(2004)
Neurosci Lett
, vol.370
, pp. 171-174
-
-
Otaegui, D.1
Paisan, C.2
Saenz, A.3
Marti, I.4
Ribate, M.5
Marti-Masso, J.F.6
Perez-Tur, J.7
Lopez De Munain, A.8
-
113
-
-
0024848034
-
Abnormalities of the electron transport chain in idiopathic Parkinson's disease
-
Parker WD, Jr., Boyson SJ, Parks JK (1989) Abnormalities of the electron transport chain in idiopathic Parkinson's disease. Ann Neurol 26: 719-723.
-
(1989)
Ann Neurol
, vol.26
, pp. 719-723
-
-
Parker Jr., W.D.1
Boyson, S.J.2
Parks, J.K.3
-
114
-
-
0034026561
-
How important is oxidative damage? Lessons from Alzheimer's disease
-
Perry G, Raina AK, Nunomura A, Wataya T, Sayre LM, Smith MA (2000) How important is oxidative damage? Lessons from Alzheimer's disease. Free Radic Biol Med 28: 831-834.
-
(2000)
Free Radic Biol Med
, vol.28
, pp. 831-834
-
-
Perry, G.1
Raina, A.K.2
Nunomura, A.3
Wataya, T.4
Sayre, L.M.5
Smith, M.A.6
-
115
-
-
26644440926
-
Wild-type PINK1 prevents basal and induced neuronal apoptosis, a protective effect abrogated by Parkinson disease-related mutations
-
Petit A, Kawarai T, Paitel E, Sanjo N, Maj M, Scheid M, Chen F, Gu Y, Hasegawa H, Salehi-Rad S, Wang L, Rogaeva E, Fraser P, Robinson B, St George-Hyslop P, Tandon A (2005) Wild-type PINK1 prevents basal and induced neuronal apoptosis, a protective effect abrogated by Parkinson disease-related mutations. J Biol Chem 280: 34025-34032.
-
(2005)
J Biol Chem
, vol.280
, pp. 34025-34032
-
-
Petit, A.1
Kawarai, T.2
Paitel, E.3
Sanjo, N.4
Maj, M.5
Scheid, M.6
Chen, F.7
Gu, Y.8
Hasegawa, H.9
Salehi-Rad, S.10
Wang, L.11
Rogaeva, E.12
Fraser, P.13
Robinson, B.14
St George-Hyslop, P.15
Tandon, A.16
-
116
-
-
13244256956
-
Comparison between the Polish population and European populations on the basis of mitochondrial morphs and haplogroups
-
Piechota J, Tonska K, Nowak M, Kabzinska D, Lorenc A, Bartnik E (2004) Comparison between the Polish population and European populations on the basis of mitochondrial morphs and haplogroups. Acta Biochim Pol 51: 883-895.
-
(2004)
Acta Biochim Pol
, vol.51
, pp. 883-895
-
-
Piechota, J.1
Tonska, K.2
Nowak, M.3
Kabzinska, D.4
Lorenc, A.5
Bartnik, E.6
-
117
-
-
20144389920
-
Mitochondrial DNA haplogroup cluster UKJT reduces the risk of PD
-
Pyle A, Foltynie T, Tiangyou W, Lambert C, Keers SM, Allcock LM, Davison J, Lewis SJ, Perry RH, Barker R, Burn DJ, Chinnery PF (2005) Mitochondrial DNA haplogroup cluster UKJT reduces the risk of PD. Ann Neurol 57: 564-567.
-
(2005)
Ann Neurol
, vol.57
, pp. 564-567
-
-
Pyle, A.1
Foltynie, T.2
Tiangyou, W.3
Lambert, C.4
Keers, S.M.5
Allcock, L.M.6
Davison, J.7
Lewis, S.J.8
Perry, R.H.9
Barker, R.10
Burn, D.J.11
Chinnery, P.F.12
-
118
-
-
33644845279
-
Amyloid precursor protein-mediated free radicals and oxidative damage: Implications for the development and progression of Alzheimer's disease
-
Reddy PH (2006) Amyloid precursor protein-mediated free radicals and oxidative damage: Implications for the development and progression of Alzheimer's disease. J Neurochem 96: 1-13.
-
(2006)
J Neurochem
, vol.96
, pp. 1-13
-
-
Reddy, P.H.1
-
119
-
-
27544484846
-
Are mitochondria critical in the pathogenesis of Alzheimer's disease?
-
Reddy PH, Beal MF (2005) Are mitochondria critical in the pathogenesis of Alzheimer's disease? Brain Res Brain Res Rev 49: 618-632.
-
(2005)
Brain Res Brain Res Rev
, vol.49
, pp. 618-632
-
-
Reddy, P.H.1
Beal, M.F.2
-
120
-
-
0036827161
-
Abeta as a bioflocculant: Implications for the amyloid hypothesis of Alzheimer's disease
-
Robinson SR, Bishop GM (2002) Abeta as a bioflocculant: implications for the amyloid hypothesis of Alzheimer's disease. Neurobiol Aging 23: 1051-1072.
-
(2002)
Neurobiol Aging
, vol.23
, pp. 1051-1072
-
-
Robinson, S.R.1
Bishop, G.M.2
-
122
-
-
0034804170
-
Paradoxes in longevity: Sequence analysis of mtDNA haplogroup J in centenarians
-
Rose G, Passarino G, Carrieri G, Altomare K, Greco V, Bertolini S, Bonafe M, Franceschi C, De Benedictis G (2001) Paradoxes in longevity: Sequence analysis of mtDNA haplogroup J in centenarians. Eur J Hum Genet 9: 701-707.
-
(2001)
Eur J Hum Genet
, vol.9
, pp. 701-707
-
-
Rose, G.1
Passarino, G.2
Carrieri, G.3
Altomare, K.4
Greco, V.5
Bertolini, S.6
Bonafe, M.7
Franceschi, C.8
De Benedictis, G.9
-
123
-
-
0034973482
-
Mitochondrial DNA polymorphism: Its role in longevity of the Irish population
-
Ross OA, McCormack R, Curran MD, Duguid RA, Barnett YA, Rea IM, Middleton D (2001) Mitochondrial DNA polymorphism: Its role in longevity of the Irish population. Exp Gerontol 36: 1161-1178.
-
(2001)
Exp Gerontol
, vol.36
, pp. 1161-1178
-
-
Ross, O.A.1
McCormack, R.2
Curran, M.D.3
Duguid, R.A.4
Barnett, Y.A.5
Rea, I.M.6
Middleton, D.7
-
124
-
-
0037380725
-
mt4216C variant in linkage with the mtDNA TJ cluster may confer a susceptibility to mitochondrial dysfunction resulting in an increased risk of Parkinson's disease in the Irish
-
Ross OA, McCormack R, Maxwell LD, Duguid RA, Quinn DJ, Barnett YA, Rea IM, El-Agnaf OM, Gibson JM, Wallace A, Middleton D, Curran MD (2003) mt4216C variant in linkage with the mtDNA TJ cluster may confer a susceptibility to mitochondrial dysfunction resulting in an increased risk of Parkinson's disease in the Irish. Exp Gerontol 38: 397-405.
-
(2003)
Exp Gerontol
, vol.38
, pp. 397-405
-
-
Ross, O.A.1
McCormack, R.2
Maxwell, L.D.3
Duguid, R.A.4
Quinn, D.J.5
Barnett, Y.A.6
Rea, I.M.7
El-Agnaf, O.M.8
Gibson, J.M.9
Wallace, A.10
Middleton, D.11
Curran, M.D.12
-
125
-
-
0036862315
-
Is amyloid beta-peptide neurotoxic or neuroprotective and what is its role in the binding of metal ions?
-
Savory J, Ghribi O, Herman MM (2002) Is amyloid beta-peptide neurotoxic or neuroprotective and what is its role in the binding of metal ions? Neurobiol Aging 23: 1089-1092.
-
(2002)
Neurobiol Aging
, vol.23
, pp. 1089-1092
-
-
Savory, J.1
Ghribi, O.2
Herman, M.M.3
-
126
-
-
0032813088
-
Repair of DNA damage in mitochondria
-
Sawyer DE, Van Houten B (1999) Repair of DNA damage in mitochondria. Mutat Res 434: 161-176.
-
(1999)
Mutat Res
, vol.434
, pp. 161-176
-
-
Sawyer, D.E.1
Van Houten, B.2
-
127
-
-
0035990290
-
Primary and secondary defects of the mitochondrial respiratory chain
-
Schapira AH (2002) Primary and secondary defects of the mitochondrial respiratory chain. J Inherit Metab Dis 25: 207-214.
-
(2002)
J Inherit Metab Dis
, vol.25
, pp. 207-214
-
-
Schapira, A.H.1
-
128
-
-
0025254401
-
Mitochondrial complex I deficiency in Parkinson's disease
-
Schapira AH, Cooper JM, Dexter D, Clark JB, Jenner P, Marsden CD (1990) Mitochondrial complex I deficiency in Parkinson's disease. J Neurochem 54: 823-827.
-
(1990)
J Neurochem
, vol.54
, pp. 823-827
-
-
Schapira, A.H.1
Cooper, J.M.2
Dexter, D.3
Clark, J.B.4
Jenner, P.5
Marsden, C.D.6
-
129
-
-
21144434217
-
Extension of murine life span by overexpression of catalase targeted to mitochondria
-
Schriner SE, Linford NJ, Martin GM, Treuting P, Ogburn CE, Emond M, Coskun PE, Ladiges W, Wolf N, Van Remmen H, Wallace DC, Rabinovitch PS (2005) Extension of murine life span by overexpression of catalase targeted to mitochondria. Science 308: 1909-1911.
-
(2005)
Science
, vol.308
, pp. 1909-1911
-
-
Schriner, S.E.1
Linford, N.J.2
Martin, G.M.3
Treuting, P.4
Ogburn, C.E.5
Emond, M.6
Coskun, P.E.7
Ladiges, W.8
Wolf, N.9
Van Remmen, H.10
Wallace, D.C.11
Rabinovitch, P.S.12
-
130
-
-
0032211830
-
The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease
-
Selkoe DJ (1998) The cell biology of beta-amyloid precursor protein and presenilin in Alzheimer's disease. Trends Cell Biol 8: 447-453.
-
(1998)
Trends Cell Biol
, vol.8
, pp. 447-453
-
-
Selkoe, D.J.1
-
131
-
-
0037104723
-
An in vitro model of Parkinson's disease: Linking mitochondrial impairment to altered alpha-synuclein metabolism and oxidative damage
-
Sherer TB, Betarbet R, Stout AK, Lund S, Baptista M, Panov AV, Cookson MR, Greenamyre JT (2002) An in vitro model of Parkinson's disease: Linking mitochondrial impairment to altered alpha-synuclein metabolism and oxidative damage. J Neurosci 22: 7006-7015.
-
(2002)
J Neurosci
, vol.22
, pp. 7006-7015
-
-
Sherer, T.B.1
Betarbet, R.2
Stout, A.K.3
Lund, S.4
Baptista, M.5
Panov, A.V.6
Cookson, M.R.7
Greenamyre, J.T.8
-
133
-
-
0027200741
-
Mitochondrial DNA variants observed in Alzheimer disease and Parkinson disease patients
-
Shoffner JM, Brown MD, Torroni A, Lott MT, Cabell MF, Mirra SS, Beal MF, Yang CC, Gearing M, Salvo R, et al. (1993) Mitochondrial DNA variants observed in Alzheimer disease and Parkinson disease patients. Genomics 17: 171-184.
-
(1993)
Genomics
, vol.17
, pp. 171-184
-
-
Shoffner, J.M.1
Brown, M.D.2
Torroni, A.3
Lott, M.T.4
Cabell, M.F.5
Mirra, S.S.6
Beal, M.F.7
Yang, C.C.8
Gearing, M.9
Salvo, R.10
-
134
-
-
18444418049
-
Mitochondrial genome diversity of Native Americans supports a single early entry of founder populations into America
-
Silva WA, Jr., Bonatto SL, Holanda AJ, Ribeiro-Dos-Santos AK, Paixao BM, Goldman GH, Abe-Sandes K, Rodriguez-Delfin L, Barbosa M, Paco-Larson ML, Petzl-Erler ML, Valente V, Santos SE, Zago MA (2002) Mitochondrial genome diversity of Native Americans supports a single early entry of founder populations into America. Am J Hum Genet 71: 187-192.
-
(2002)
Am J Hum Genet
, vol.71
, pp. 187-192
-
-
Silva Jr., W.A.1
Bonatto, S.L.2
Holanda, A.J.3
Ribeiro-Dos-Santos, A.K.4
Paixao, B.M.5
Goldman, G.H.6
Abe-Sandes, K.7
Rodriguez-Delfin, L.8
Barbosa, M.9
Paco-Larson, M.L.10
Petzl-Erler, M.L.11
Valente, V.12
Santos, S.E.13
Zago, M.A.14
-
135
-
-
0034620483
-
Mitochondrial DNA mutations in complex I and tRNA genes in Parkinson's disease
-
Simon DK, Mayeux R, Marder K, Kowall NW, Beal MF, Johns DR (2000) Mitochondrial DNA mutations in complex I and tRNA genes in Parkinson's disease. Neurology 54: 703-709.
-
(2000)
Neurology
, vol.54
, pp. 703-709
-
-
Simon, D.K.1
Mayeux, R.2
Marder, K.3
Kowall, N.W.4
Beal, M.F.5
Johns, D.R.6
-
136
-
-
0035309740
-
Low mutational burden of individual acquired mitochondrial DNA mutations in brain
-
Simon DK, Lin MT, Ahn CH, Liu GJ, Gibson GE, Beal MF, Johns DR (2001) Low mutational burden of individual acquired mitochondrial DNA mutations in brain. Genomics 73: 113-116.
-
(2001)
Genomics
, vol.73
, pp. 113-116
-
-
Simon, D.K.1
Lin, M.T.2
Ahn, C.H.3
Liu, G.J.4
Gibson, G.E.5
Beal, M.F.6
Johns, D.R.7
-
137
-
-
10744231633
-
Somatic mitochondrial DNA mutations in cortex and substantia nigra in aging and Parkinson's disease
-
Simon DK, Lin MT, Zheng L, Liu GJ, Ahn CH, Kim LM, Mauck WM, Twu F, Beal MF, Johns DR (2004) Somatic mitochondrial DNA mutations in cortex and substantia nigra in aging and Parkinson's disease. Neurobiol Aging 25: 71-81.
-
(2004)
Neurobiol Aging
, vol.25
, pp. 71-81
-
-
Simon, D.K.1
Lin, M.T.2
Zheng, L.3
Liu, G.J.4
Ahn, C.H.5
Kim, L.M.6
Mauck, W.M.7
Twu, F.8
Beal, M.F.9
Johns, D.R.10
-
138
-
-
4644351698
-
High frequency of mitochondrial complex I mutations in Parkinson's disease and aging
-
Smigrodzki R, Parks J, Parker WD (2004) High frequency of mitochondrial complex I mutations in Parkinson's disease and aging. Neurobiol Aging 25: 1273-1281.
-
(2004)
Neurobiol Aging
, vol.25
, pp. 1273-1281
-
-
Smigrodzki, R.1
Parks, J.2
Parker, W.D.3
-
139
-
-
24944435398
-
Mitochondrial microheteroplasmy and a theory of aging and age-related disease
-
Smigrodzki RM, Khan SM (2005) Mitochondrial microheteroplasmy and a theory of aging and age-related disease. Rejuvenation Res 8: 172-198.
-
(2005)
Rejuvenation Res
, vol.8
, pp. 172-198
-
-
Smigrodzki, R.M.1
Khan, S.M.2
-
140
-
-
13644249113
-
Chronological primacy of oxidative stress in Alzheimer disease
-
Smith MA, Nunomura A, Lee HG, Zhu X, Moreira PI, Avila J, Perry G (2005) Chronological primacy of oxidative stress in Alzheimer disease. Neurobiol Aging 26: 579-580.
-
(2005)
Neurobiol Aging
, vol.26
, pp. 579-580
-
-
Smith, M.A.1
Nunomura, A.2
Lee, H.G.3
Zhu, X.4
Moreira, P.I.5
Avila, J.6
Perry, G.7
-
141
-
-
17044364766
-
DNA precursor asymmetries in mammalian tissue mitochondria and possible contribution to mutagenesis through reduced replication fidelity
-
U S A
-
Song S, Pursell ZF, Copeland WC, Longley MJ, Kunkel TA, Mathews CK (2005) DNA precursor asymmetries in mammalian tissue mitochondria and possible contribution to mutagenesis through reduced replication fidelity. Proc Natl Acad Sci U S A 102: 4990-4995.
-
(2005)
Proc Natl Acad Sci
, vol.102
, pp. 4990-4995
-
-
Song, S.1
Pursell, Z.F.2
Copeland, W.C.3
Longley, M.J.4
Kunkel, T.A.5
Mathews, C.K.6
-
142
-
-
25444498785
-
Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease
-
Strauss KM, Martins LM, Plun-Favreau H, Marx FP, Kautzmann S, Berg D, Gasser T, Wszolek Z, Muller T, Bornemann A, Wolburg H, Downward J, Riess O, Schulz JB, Kruger R (2005) Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease. Hum Mol Genet 14: 2099-2111.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 2099-2111
-
-
Strauss, K.M.1
Martins, L.M.2
Plun-Favreau, H.3
Marx, F.P.4
Kautzmann, S.5
Berg, D.6
Gasser, T.7
Wszolek, Z.8
Muller, T.9
Bornemann, A.10
Wolburg, H.11
Downward, J.12
Riess, O.13
Schulz, J.B.14
Kruger, R.15
-
143
-
-
0038018658
-
Simultaneous analysis of five genetic risk factors in Polish patients with Alzheimer's disease
-
Styczynska M, Religa D, Pfeffer A, Luczywek E, Wasiak B, Styczynski G, Peplonska B, Gabryelewicz T, Golebiowski M, Kobrys M, Barcikowska M (2003) Simultaneous analysis of five genetic risk factors in Polish patients with Alzheimer's disease. Neurosci Lett 344: 99-102.
-
(2003)
Neurosci Lett
, vol.344
, pp. 99-102
-
-
Styczynska, M.1
Religa, D.2
Pfeffer, A.3
Luczywek, E.4
Wasiak, B.5
Styczynski, G.6
Peplonska, B.7
Gabryelewicz, T.8
Golebiowski, M.9
Kobrys, M.10
Barcikowska, M.11
-
145
-
-
0032504575
-
Mitochondria as regulators of apoptosis: Doubt no more
-
Susin SA, Zamzami N, Kroemer G (1998) Mitochondria as regulators of apoptosis: Doubt no more. Biochim Biophys Acta 1366: 151-165.
-
(1998)
Biochim Biophys Acta
, vol.1366
, pp. 151-165
-
-
Susin, S.A.1
Zamzami, N.2
Kroemer, G.3
-
146
-
-
3042806534
-
A "mitochondrial cascade hypothesis" for sporadic Alzheimer's disease
-
Swerdlow RH, Khan SM (2004) A "mitochondrial cascade hypothesis" for sporadic Alzheimer's disease. Med Hypotheses 63: 8-20.
-
(2004)
Med Hypotheses
, vol.63
, pp. 8-20
-
-
Swerdlow, R.H.1
Khan, S.M.2
-
147
-
-
0036982389
-
Mitochondria in Alzheimer's disease
-
Swerdlow RH, Kish SJ (2002) Mitochondria in Alzheimer's disease. Int Rev Neurobiol 53: 341-385.
-
(2002)
Int Rev Neurobiol
, vol.53
, pp. 341-385
-
-
Swerdlow, R.H.1
Kish, S.J.2
-
148
-
-
0029908226
-
Origin and functional consequences of the complex I defect in Parkinson's disease
-
Swerdlow RH, Parks JK, Miller SW, Tuttle JB, Trimmer PA, Sheehan JP, Bennett JP, Jr., Davis RE, Parker WD, Jr. (1996) Origin and functional consequences of the complex I defect in Parkinson's disease. Ann Neurol 40: 663-671.
-
(1996)
Ann Neurol
, vol.40
, pp. 663-671
-
-
Swerdlow, R.H.1
Parks, J.K.2
Miller, S.W.3
Tuttle, J.B.4
Trimmer, P.A.5
Sheehan, J.P.6
Bennett Jr., J.P.7
Davis, R.E.8
Parker Jr., W.D.9
-
149
-
-
0032539447
-
Mitochondrial genotype associated with longevity
-
Tanaka M, Gong JS, Zhang J, Yoneda M, Yagi K (1998) Mitochondrial genotype associated with longevity. Lancet 351: 185-186.
-
(1998)
Lancet
, vol.351
, pp. 185-186
-
-
Tanaka, M.1
Gong, J.S.2
Zhang, J.3
Yoneda, M.4
Yagi, K.5
-
150
-
-
0034738386
-
Mitochondrial genotype associated with longevity and its inhibitory effect on mutagenesis
-
Tanaka M, Gong J, Zhang J, Yamada Y, Borgeld HJ, Yagi K (2000) Mitochondrial genotype associated with longevity and its inhibitory effect on mutagenesis. Mech Ageing Dev 116: 65-76.
-
(2000)
Mech Ageing Dev
, vol.116
, pp. 65-76
-
-
Tanaka, M.1
Gong, J.2
Zhang, J.3
Yamada, Y.4
Borgeld, H.J.5
Yagi, K.6
-
151
-
-
2342620627
-
Mitochondrial genome single nucleotide polymorphisms and their phenotypes in the Japanese
-
Tanaka M, Takeyasu T, Fuku N, Li-Jun G, Kurata M (2004) Mitochondrial genome single nucleotide polymorphisms and their phenotypes in the Japanese. Ann N Y Acad Sci 1011: 7-20.
-
(2004)
Ann N Y Acad Sci
, vol.1011
, pp. 7-20
-
-
Tanaka, M.1
Takeyasu, T.2
Fuku, N.3
Li-Jun, G.4
Kurata, M.5
-
152
-
-
12844288997
-
Widespread gamma-secretase activity in the cell, but do we need it at the mitochondria?
-
Teng FY, Tang BL (2005) Widespread gamma-secretase activity in the cell, but do we need it at the mitochondria? Biochem Biophys Res Commun 328: 1-5.
-
(2005)
Biochem Biophys Res Commun
, vol.328
, pp. 1-5
-
-
Teng, F.Y.1
Tang, B.L.2
-
153
-
-
0028332916
-
Mitochondrial DNA variation in human populations and implications for detection of mitochondrial DNA mutations of pathological significance
-
Torroni A, Wallace DC (1994) Mitochondrial DNA variation in human populations and implications for detection of mitochondrial DNA mutations of pathological significance. J Bioenerg Biomembr 26: 261-271.
-
(1994)
J Bioenerg Biomembr
, vol.26
, pp. 261-271
-
-
Torroni, A.1
Wallace, D.C.2
-
154
-
-
1042301278
-
Parkinson's disease transgenic mitochondrial cybrids generate Lewy inclusion bodies
-
Trimmer PA, Borland MK, Keeney PM, Bennett JP, Jr., Parker WD, Jr. (2004) Parkinson's disease transgenic mitochondrial cybrids generate Lewy inclusion bodies. J Neurochem 88: 800-812.
-
(2004)
J Neurochem
, vol.88
, pp. 800-812
-
-
Trimmer, P.A.1
Borland, M.K.2
Keeney, P.M.3
Bennett Jr., J.P.4
Parker Jr., W.D.5
-
155
-
-
0037675042
-
Incidence of Parkinson's disease: Variation by age, gender, and race/ethnicity
-
Van Den Eeden SK, Tanner CM, Bernstein AL, Fross RD, Leimpeter A, Bloch DA, Nelson LM (2003) Incidence of Parkinson's disease: Variation by age, gender, and race/ethnicity. Am J Epidemiol 157: 1015-1022.
-
(2003)
Am J Epidemiol
, vol.157
, pp. 1015-1022
-
-
Van Den Eeden, S.K.1
Tanner, C.M.2
Bernstein, A.L.3
Fross, R.D.4
Leimpeter, A.5
Bloch, D.A.6
Nelson, L.M.7
-
156
-
-
0037385480
-
Mitochondrial polymorphisms significantly reduce the risk of Parkinson disease
-
van der Walt JM, Nicodemus KK, Martin ER, Scott WK, Nance MA, Watts RL, Hubble JP, Haines JL, Koller WC, Lyons K, Pahwa R, Stern MB, Colcher A, Hiner BC, Jankovic J, Ondo WG, Allen FH, Jr., Goetz CG, Small GW, Mastaglia F, Stajich JM, McLaurin AC, Middleton LT, Scott BL, Schmechel DE, Pericak-Vance MA, Vance JM (2003) Mitochondrial polymorphisms significantly reduce the risk of Parkinson disease. Am J Hum Genet 72: 804-811.
-
(2003)
Am J Hum Genet
, vol.72
, pp. 804-811
-
-
Van Der Walt, J.M.1
Nicodemus, K.K.2
Martin, E.R.3
Scott, W.K.4
Nance, M.A.5
Watts, R.L.6
Hubble, J.P.7
Haines, J.L.8
Koller, W.C.9
Lyons, K.10
Pahwa, R.11
Stern, M.B.12
Colcher, A.13
Hiner, B.C.14
Jankovic, J.15
Ondo, W.G.16
Allen Jr., F.H.17
Goetz, C.G.18
Small, G.W.19
Mastaglia, F.20
Stajich, J.M.21
McLaurin, A.C.22
Middleton, L.T.23
Scott, B.L.24
Schmechel, D.E.25
Pericak-Vance, M.A.26
Vance, J.M.27
more..
-
157
-
-
3242707016
-
Analysis of European mitochondrial haplogroups with Alzheimer disease risk
-
van der Walt JM, Dementieva YA, Martin ER, Scott WK, Nicodemus KK, Kroner CC, Welsh-Bohmer KA, Saunders AM, Roses AD, Small GW, Schmechel DE, Murali Doraiswamy P, Gilbert JR, Haines JL, Vance JM, Pericak-Vance MA (2004) Analysis of European mitochondrial haplogroups with Alzheimer disease risk. Neurosci Lett 365: 28-32.
-
(2004)
Neurosci Lett
, vol.365
, pp. 28-32
-
-
Van Der Walt, J.M.1
Dementieva, Y.A.2
Martin, E.R.3
Scott, W.K.4
Nicodemus, K.K.5
Kroner, C.C.6
Welsh-Bohmer, K.A.7
Saunders, A.M.8
Roses, A.D.9
Small, G.W.10
Schmechel, D.E.11
Murali Doraiswamy, P.12
Gilbert, J.R.13
Haines, J.L.14
Vance, J.M.15
Pericak-Vance, M.A.16
-
158
-
-
0036297660
-
Sequence analysis of the entire mitochondrial genome in Parkinson's disease
-
Vives-Bauza C, Andreu AL, Manfredi G, Beal MF, Janetzky B, Gruenewald TH, Lin MT (2002) Sequence analysis of the entire mitochondrial genome in Parkinson's disease. Biochem Biophys Res Commun 290: 1593-1601.
-
(2002)
Biochem Biophys Res Commun
, vol.290
, pp. 1593-1601
-
-
Vives-Bauza, C.1
Andreu, A.L.2
Manfredi, G.3
Beal, M.F.4
Janetzky, B.5
Gruenewald, T.H.6
Lin, M.T.7
-
159
-
-
28444445608
-
Enhanced ROS production and antioxidant defenses in cybrids harbouring mutations in mtDNA
-
Vives-Bauza C, Gonzalo R, Manfredi G, Garcia-Arumi E, Andreu AL (2006) Enhanced ROS production and antioxidant defenses in cybrids harbouring mutations in mtDNA. Neurosci Lett 391: 136-141.
-
(2006)
Neurosci Lett
, vol.391
, pp. 136-141
-
-
Vives-Bauza, C.1
Gonzalo, R.2
Manfredi, G.3
Garcia-Arumi, E.4
Andreu, A.L.5
-
160
-
-
0032833421
-
Mitochondrial DNA variation in human evolution and disease
-
Wallace DC, Brown MD, Lott MT (1999) Mitochondrial DNA variation in human evolution and disease. Gene 238: 211-230.
-
(1999)
Gene
, vol.238
, pp. 211-230
-
-
Wallace, D.C.1
Brown, M.D.2
Lott, M.T.3
-
161
-
-
0028843809
-
No association found between Alzheimer's disease and a mitochondrial tRNA glutamine gene variant
-
Wragg MA, Talbot CJ, Morris JC, Lendon CL, Goate AM (1995) No association found between Alzheimer's disease and a mitochondrial tRNA glutamine gene variant. Neurosci Lett 201: 107-110.
-
(1995)
Neurosci Lett
, vol.201
, pp. 107-110
-
-
Wragg, M.A.1
Talbot, C.J.2
Morris, J.C.3
Lendon, C.L.4
Goate, A.M.5
-
162
-
-
0026457825
-
Marked replicative advantage of human mtDNA carrying a point mutation that causes the MELAS encephalomyopathy
-
U S A
-
Yoneda M, Chomyn A, Martinuzzi A, Hurko O, Attardi G (1992) Marked replicative advantage of human mtDNA carrying a point mutation that causes the MELAS encephalomyopathy. Proc Natl Acad Sci U S A 89: 11164-11168.
-
(1992)
Proc Natl Acad Sci
, vol.89
, pp. 11164-11168
-
-
Yoneda, M.1
Chomyn, A.2
Martinuzzi, A.3
Hurko, O.4
Attardi, G.5
-
163
-
-
1842607579
-
Genetic aspects of Alzheimer's disease
-
Wars
-
Zekanowski C, Religa D, Graff C, Filipek S, Kuznicki J (2004) Genetic aspects of Alzheimer's disease. Acta Neurobiol Exp (Wars) 64: 19-31.
-
(2004)
Acta Neurobiol Exp
, vol.64
, pp. 19-31
-
-
Zekanowski, C.1
Religa, D.2
Graff, C.3
Filipek, S.4
Kuznicki, J.5
-
164
-
-
0037417898
-
Strikingly higher frequency in centenarians and twins of mtDNA mutation causing remodeling of replication origin in leukocytes
-
U S A
-
Zhang J, Asin-Cayuela J, Fish J, Michikawa Y, Bonafe M, Olivieri F, Passarino G, De Benedictis G, Franceschi C, Attardi G (2003) Strikingly higher frequency in centenarians and twins of mtDNA mutation causing remodeling of replication origin in leukocytes. Proc Natl Acad Sci U S A 100: 1116-1121.
-
(2003)
Proc Natl Acad Sci
, vol.100
, pp. 1116-1121
-
-
Zhang, J.1
Asin-Cayuela, J.2
Fish, J.3
Michikawa, Y.4
Bonafe, M.5
Olivieri, F.6
Passarino, G.7
De Benedictis, G.8
Franceschi, C.9
Attardi, G.10
|