-
1
-
-
0028007092
-
DNA oxidative damage and life expectancy in houseflies
-
Agarval S and Sohal RS. DNA oxidative damage and life expectancy in houseflies. Proc Natl Acad Sci USA 91: 12332-12335, 1994.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 12332-12335
-
-
Agarval, S.1
Sohal, R.S.2
-
2
-
-
0037009120
-
Membrane protein degradation by AAA proteases in mitochondria
-
Arnold I and Langer T. Membrane protein degradation by AAA proteases in mitochondria. Biochim Biophys Acta 1592: 89-96, 2002.
-
(2002)
Biochim Biophys Acta
, vol.1592
, pp. 89-96
-
-
Arnold, I.1
Langer, T.2
-
3
-
-
0037517056
-
Changes in rat liver mitochondria with aging. Lon protease-like reactivity and N(epsilon)-carboxymethyllysine accumulation in the matrix
-
Bakala H, Delaval E, Hamelin M, Bismuth J, Borot-Laloi C, Corman B, and Friguet B. Changes in rat liver mitochondria with aging. Lon protease-like reactivity and N(epsilon)-carboxymethyllysine accumulation in the matrix. Eur J Biochem 270: 2295-2302, 2003.
-
(2003)
Eur J Biochem
, vol.270
, pp. 2295-2302
-
-
Bakala, H.1
Delaval, E.2
Hamelin, M.3
Bismuth, J.4
Borot-Laloi, C.5
Corman, B.6
Friguet, B.7
-
4
-
-
0036596625
-
Endogenous oxidative stress: Relationship to aging, longevity and caloric restriction
-
Barja G. Endogenous oxidative stress: relationship to aging, longevity and caloric restriction. Ageing Res Rev 1: 397: 411, 2002.
-
(2002)
Ageing Res Rev
, vol.1
, Issue.397
, pp. 411
-
-
Barja, G.1
-
5
-
-
0036829433
-
Rate of generation of oxidative stress-related damage and animal longevity
-
Barja G. Rate of generation of oxidative stress-related damage and animal longevity. Free Radic Biol Med 33: 1167-1172, 2002.
-
(2002)
Free Radic Biol Med
, vol.33
, pp. 1167-1172
-
-
Barja, G.1
-
6
-
-
2542446099
-
Aging in vertebrates, and the effect of caloric restriction: A mitochondrial free radical production-DNA damage mechanism?
-
Barja G. Aging in vertebrates, and the effect of caloric restriction: a mitochondrial free radical production-DNA damage mechanism? Biol Rev Camb Philos Soc 79: 235-251, 2004.
-
(2004)
Biol Rev Camb Philos Soc
, vol.79
, pp. 235-251
-
-
Barja, G.1
-
7
-
-
0022894660
-
Biosynthesis, glycosylation, movement through the Golgi system, and transport to lysosomes by an N-linked carbohydrate-independent mechanism of three lysosomal integral membrane proteins
-
Barriocanal JG, Bonifacino JS, Yuan L, and Sandoval IV. Biosynthesis, glycosylation, movement through the Golgi system, and transport to lysosomes by an N-linked carbohydrate-independent mechanism of three lysosomal integral membrane proteins. J Biol Chem 261: 16755-16763, 1986.
-
(1986)
J Biol Chem
, vol.261
, pp. 16755-16763
-
-
Barriocanal, J.G.1
Bonifacino, J.S.2
Yuan, L.3
Sandoval, I.V.4
-
8
-
-
0031916984
-
The free radical theory of aging matures
-
Beckman KB and Ames BN. The free radical theory of aging matures. Physiol Rev 78: 547-581, 1998.
-
(1998)
Physiol Rev
, vol.78
, pp. 547-581
-
-
Beckman, K.B.1
Ames, B.N.2
-
9
-
-
0023804105
-
Age and sex related changes of plasma membrane fluidity in isolated rat hepatocytes
-
Benedetti A, Ferretti G, Curatola G, Jezequel AM, and Orlandi F. Age and sex related changes of plasma membrane fluidity in isolated rat hepatocytes. Biochem Biophys Res Commun 156: 840-845, 1988.
-
(1988)
Biochem Biophys Res Commun
, vol.156
, pp. 840-845
-
-
Benedetti, A.1
Ferretti, G.2
Curatola, G.3
Jezequel, A.M.4
Orlandi, F.5
-
10
-
-
14344263884
-
The role of alpha-synuclein in neurodegenerative diseases
-
Bennett MC. The role of alpha-synuclein in neurodegenerative diseases. Pharmacol Ther 105: 311-331, 2005.
-
(2005)
Pharmacol Ther
, vol.105
, pp. 311-331
-
-
Bennett, M.C.1
-
11
-
-
0031870954
-
A proposed mechanism of the antiaging action of diet restriction
-
Bergamini E, Cavallini G, Cecchi L, Donati A, Dolfi C, Gori Z, Innocenti B, Maccheroni M, Marino M, Masini M, Paradiso C, Pollera M, and Trentalance A. A proposed mechanism of the antiaging action of diet restriction. Aging (Milano) 10: 174-175, 1998.
-
(1998)
Aging (Milano)
, vol.10
, pp. 174-175
-
-
Bergamini, E.1
Cavallini, G.2
Cecchi, L.3
Donati, A.4
Dolfi, C.5
Gori, Z.6
Innocenti, B.7
Maccheroni, M.8
Marino, M.9
Masini, M.10
Paradiso, C.11
Pollera, M.12
Trentalance, A.13
-
12
-
-
0043204997
-
The anti-ageing effects of caloric restriction may involve stimulation of macroautophagy and lysosomal degradation, and can be intensified pharmacologically
-
Bergamini E, Cavallini G, Donati A, and Gori Z. The anti-ageing effects of caloric restriction may involve stimulation of macroautophagy and lysosomal degradation, and can be intensified pharmacologically. Biomed Pharmacother 57: 203-208, 2003.
-
(2003)
Biomed Pharmacother
, vol.57
, pp. 203-208
-
-
Bergamini, E.1
Cavallini, G.2
Donati, A.3
Gori, Z.4
-
13
-
-
0028908348
-
Advanced protein glycosylation in diabetes and aging
-
Brownlee M. Advanced protein glycosylation in diabetes and aging. Annu Rev Med 46: 223-234, 1995.
-
(1995)
Annu Rev Med
, vol.46
, pp. 223-234
-
-
Brownlee, M.1
-
14
-
-
0015264490
-
Electron microscopical studies of rat brain neurons. Localization of acid phosphatase and mode of formation of lipofuscin bodies
-
Brunk U and Ericsson JLE. Electron microscopical studies of rat brain neurons. Localization of acid phosphatase and mode of formation of lipofuscin bodies. J Ultrastruct Res 38: 1-15, 1972.
-
(1972)
J Ultrastruct Res
, vol.38
, pp. 1-15
-
-
Brunk, U.1
Ericsson, J.L.E.2
-
15
-
-
0026663037
-
A novel hypothesis of lipofuscinogenesis and cellular aging based on interactions between oxidative stress and autophagocytosis
-
Brunk UT, Jones CB, and Sohal RS. A novel hypothesis of lipofuscinogenesis and cellular aging based on interactions between oxidative stress and autophagocytosis. Mutat Res 275: 395-403, 1992.
-
(1992)
Mutat Res
, vol.275
, pp. 395-403
-
-
Brunk, U.T.1
Jones, C.B.2
Sohal, R.S.3
-
17
-
-
0031749350
-
Autofluorescent inclusions in long-term postconfluent cultures of retinal pigment epithelium
-
Burke JM and Skumatz CM. Autofluorescent inclusions in long-term postconfluent cultures of retinal pigment epithelium. Invest Ophthalmol Vis Sci 39: 1478-1486, 1998.
-
(1998)
Invest Ophthalmol Vis Sci
, vol.39
, pp. 1478-1486
-
-
Burke, J.M.1
Skumatz, C.M.2
-
18
-
-
0015965272
-
Intrinsic mutagenesis: A genetic basis of ageing
-
Burnet FM. Intrinsic mutagenesis: a genetic basis of ageing. Pathology 6: 1-11, 1974.
-
(1974)
Pathology
, vol.6
, pp. 1-11
-
-
Burnet, F.M.1
-
19
-
-
1842519391
-
Alzheimer's amyloid beta-peptide (1-42): Involvement of methionine residue 35 in the oxidative stress and neurotoxicity properties of this peptide
-
Butterfield DA and Bush AI. Alzheimer's amyloid beta-peptide (1-42): involvement of methionine residue 35 in the oxidative stress and neurotoxicity properties of this peptide. Neurobiol Aging 25: 563-568, 2004.
-
(2004)
Neurobiol Aging
, vol.25
, pp. 563-568
-
-
Butterfield, D.A.1
Bush, A.I.2
-
20
-
-
0033796250
-
Mitochondrial free radical generation, oxidative stress, and aging
-
Cadenas E and Davies KJ. Mitochondrial free radical generation, oxidative stress, and aging. Free Radic Biol Med 29: 222-230, 2000.
-
(2000)
Free Radic Biol Med
, vol.29
, pp. 222-230
-
-
Cadenas, E.1
Davies, K.J.2
-
21
-
-
0034069237
-
Cancer, aging and cellular senescence
-
Campisi J. Cancer, aging and cellular senescence. In Vivo 14: 183-188, 2000.
-
(2000)
In Vivo
, vol.14
, pp. 183-188
-
-
Campisi, J.1
-
22
-
-
0038049143
-
Cancer and ageing: Rival demons?
-
Campisi J. Cancer and ageing: rival demons? Nat Rev Cancer 3: 339-349, 2003.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 339-349
-
-
Campisi, J.1
-
23
-
-
0035504933
-
Mitochondrial DNA deletion mutations are concomitant with ragged red regions of individual, aged muscle fibers: Analysis by laser-capture microdissection
-
Cao Z, Wanagat J, McKiernan SH, and Aiken JM. Mitochondrial DNA deletion mutations are concomitant with ragged red regions of individual, aged muscle fibers: analysis by laser-capture microdissection. Nucleic Acids Res 29: 4502-4508, 2001.
-
(2001)
Nucleic Acids Res
, vol.29
, pp. 4502-4508
-
-
Cao, Z.1
Wanagat, J.2
McKiernan, S.H.3
Aiken, J.M.4
-
24
-
-
0031669208
-
Effect of a continuous gamma irradiation at a very low dose on the life span of mice
-
Caratero A, Courtade M, Bonnet L, Planel H, and Caratero C. Effect of a continuous gamma irradiation at a very low dose on the life span of mice. Gerontology 44: 272-276, 1998.
-
(1998)
Gerontology
, vol.44
, pp. 272-276
-
-
Caratero, A.1
Courtade, M.2
Bonnet, L.3
Planel, H.4
Caratero, C.5
-
25
-
-
4544385218
-
Autophagy: Many paths to the same end
-
Cuervo AM. Autophagy: many paths to the same end. Mol Cell Biochem 263: 55-72, 2004.
-
(2004)
Mol Cell Biochem
, vol.263
, pp. 55-72
-
-
Cuervo, A.M.1
-
26
-
-
0031081410
-
A proposed refinement of the mitochondrial free radical theory of aging
-
de Grey AD. A proposed refinement of the mitochondrial free radical theory of aging. BioEssays 19: 161-166, 1997.
-
(1997)
BioEssays
, vol.19
, pp. 161-166
-
-
Grey, A.D.1
-
27
-
-
0036843801
-
Bioremediation meets biomedicine: Therapeutic translation of microbial catabolism to the lysosome
-
de Grey AD. Bioremediation meets biomedicine: therapeutic translation of microbial catabolism to the lysosome. Trends Biotechnol 20: 452-455, 2002.
-
(2002)
Trends Biotechnol
, vol.20
, pp. 452-455
-
-
De Grey, A.D.1
-
28
-
-
0035984192
-
HO2*: The forgotten radical
-
De Grey AD. HO2*: the forgotten radical. DNA Cell Biol 21: 251-257, 2002.
-
(2002)
DNA Cell Biol
, vol.21
, pp. 251-257
-
-
De Grey, A.D.1
-
29
-
-
0025636261
-
Spontaneous activity level and life span in rotifers: Lack of support for the rate of living theory
-
Enesco HE, McTavish A, and Garberi R. Spontaneous activity level and life span in rotifers: lack of support for the rate of living theory. Gerontology 36: 256-261, 1990.
-
(1990)
Gerontology
, vol.36
, pp. 256-261
-
-
Enesco, H.E.1
McTavish, A.2
Garberi, R.3
-
30
-
-
10044298597
-
Reversal of a hallmark of brain ageing: Lipofuscin accumulation
-
Fonseca DB, Sheehy MR, Blackman N, Shelton PM, and Prior AE. Reversal of a hallmark of brain ageing: lipofuscin accumulation. Neurobiol Aging 26: 69-76, 2005.
-
(2005)
Neurobiol Aging
, vol.26
, pp. 69-76
-
-
Fonseca, D.B.1
Sheehy, M.R.2
Blackman, N.3
Shelton, P.M.4
Prior, A.E.5
-
31
-
-
0036372751
-
Aging of proteins and the proteasome
-
Friguet B. Aging of proteins and the proteasome. Prog Molec Subcell Biol 29: 17-33, 2002.
-
(2002)
Prog Molec Subcell Biol
, vol.29
, pp. 17-33
-
-
Friguet, B.1
-
32
-
-
0033606902
-
Nematode ageing: Putting metabolic theories to the test
-
Gems D. Nematode ageing: Putting metabolic theories to the test. Curr Biol 9: R614-616, 1999.
-
(1999)
Curr Biol
, vol.9
-
-
Gems, D.1
-
33
-
-
0033622324
-
Intraneuronal Abeta42 accumulation in human brain
-
Gouras GK, Tsai J, Naslund J, Vincent B, Edgar M, Checler F, Greenfield JP, Haroutunian V, Buxbaum JD, Xu H, Greengard P, and Relkin NR. Intraneuronal Abeta42 accumulation in human brain. Am J Pathol 156: 15-20, 2000.
-
(2000)
Am J Pathol
, vol.156
, pp. 15-20
-
-
Gouras, G.K.1
Tsai, J.2
Naslund, J.3
Vincent, B.4
Edgar, M.5
Checler, F.6
Greenfield, J.P.7
Haroutunian, V.8
Buxbaum, J.D.9
Xu, H.10
Greengard, P.11
Relkin, N.R.12
-
34
-
-
4344677922
-
Decreased proteolysis caused by protein aggregates, inclusion bodies, plaques, lipofuscin, ceroid, and 'aggresomes' during oxidative stress, aging, and disease
-
Grune T, Jung T, Merker K, and Davies KJ. Decreased proteolysis caused by protein aggregates, inclusion bodies, plaques, lipofuscin, ceroid, and 'aggresomes' during oxidative stress, aging, and disease. Int J Biochem Cell Biol 36: 2519-2530, 2004.
-
(2004)
Int J Biochem Cell Biol
, vol.36
, pp. 2519-2530
-
-
Grune, T.1
Jung, T.2
Merker, K.3
Davies, K.J.4
-
36
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
-
Hardy J and Selkoe DJ. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 297: 353-356, 2002.
-
(2002)
Science
, vol.297
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
37
-
-
77049308856
-
Aging: A theory based on free radical and radiation chemistry
-
Harman D. Aging: a theory based on free radical and radiation chemistry. J Gerontol 211: 298-300, 1956.
-
(1956)
J Gerontol
, vol.211
, pp. 298-300
-
-
Harman, D.1
-
38
-
-
0015319592
-
The biologic clock: The mitochondria?
-
Harman D. The biologic clock: the mitochondria? J Am Geriatr Soc 20: 145-147, 1972.
-
(1972)
J Am Geriatr Soc
, vol.20
, pp. 145-147
-
-
Harman, D.1
-
39
-
-
0025074187
-
Lipofuscin and ceroid formation: The cellular recycling system
-
Harman D. Lipofuscin and ceroid formation: the cellular recycling system. Adv Exp Med Biol 266: 3-15, 1989.
-
(1989)
Adv Exp Med Biol
, vol.266
, pp. 3-15
-
-
Harman, D.1
-
40
-
-
0028223426
-
Free-radical theory of aging. Increasing the functional life span
-
Harman D. Free-radical theory of aging. Increasing the functional life span. Ann NY Acad Sci 717: 1-15, 1994.
-
(1994)
Ann NY Acad Sci
, vol.717
, pp. 1-15
-
-
Harman, D.1
-
41
-
-
4344661620
-
Non-oxidative modification of DNA and proteins
-
von Zglinicki T, ed. Dordrecht: Kluwer
-
Hipkiss AR. Non-oxidative modification of DNA and proteins. In: Aging at the Molecular Level, von Zglinicki T, ed. Dordrecht: Kluwer, 2003; 145-177.
-
(2003)
Aging at the Molecular Level
, pp. 145-177
-
-
Hipkiss, A.R.1
-
42
-
-
0023550044
-
Ultrastructural changes in the frontal cortex and hippocampus in the ageing marmoset
-
Honavar M and Lantos PL. Ultrastructural changes in the frontal cortex and hippocampus in the ageing marmoset. Mech Ageing Dev 41: 161-175, 1987.
-
(1987)
Mech Ageing Dev
, vol.41
, pp. 161-175
-
-
Honavar, M.1
Lantos, P.L.2
-
43
-
-
0029563691
-
Lipofuscin in bovine muscle and brain: A model for studying age pigment
-
Jolly RD, Douglas BV, Davey PM, and Roiri JE. Lipofuscin in bovine muscle and brain: a model for studying age pigment. Gerontology 41: 283-295, 1995.
-
(1995)
Gerontology
, vol.41
, pp. 283-295
-
-
Jolly, R.D.1
Douglas, B.V.2
Davey, P.M.3
Roiri, J.E.4
-
44
-
-
0033151863
-
Cell-by-cell scanning of whole mitochondrial genomes in aged human heart reveals a significant fraction of myocytes with clonally expanded deletions
-
Khrapko K, Bodyak N, Thilly WG, van Orsouw NJ, Zhang X, Coller HA, Perls TT, Upton M, Vijg J, and Wei JY. Cell-by-cell scanning of whole mitochondrial genomes in aged human heart reveals a significant fraction of myocytes with clonally expanded deletions. Nucleic Acids Res 27: 2434-2441, 1999.
-
(1999)
Nucleic Acids Res
, vol.27
, pp. 2434-2441
-
-
Khrapko, K.1
Bodyak, N.2
Thilly, W.G.3
Van Orsouw, N.J.4
Zhang, X.5
Coller, H.A.6
Perls, T.T.7
Upton, M.8
Vijg, J.9
Wei, J.Y.10
-
45
-
-
0024546310
-
DNA, mutations and aging
-
Kirkwood TB. DNA, mutations and aging. Mutat Res 219: 1-7, 1989.
-
(1989)
Mutat Res
, vol.219
, pp. 1-7
-
-
Kirkwood, T.B.1
-
46
-
-
0029890534
-
A network theory of ageing: The interactions of defective mitochondria, aberrant proteins, free radicals and scavengers in the ageing process
-
Kowald A and Kirkwood TB. A network theory of ageing: the interactions of defective mitochondria, aberrant proteins, free radicals and scavengers in the ageing process. Mutat Res 316: 209-236, 1996.
-
(1996)
Mutat Res
, vol.316
, pp. 209-236
-
-
Kowald, A.1
Kirkwood, T.B.2
-
47
-
-
0027097908
-
Role of glycation in aging
-
Lee AT and Cerami A. Role of glycation in aging. Ann N Y Acad Sci 663: 63-70, 1992.
-
(1992)
Ann N Y Acad Sci
, vol.663
, pp. 63-70
-
-
Lee, A.T.1
Cerami, A.2
-
48
-
-
1842583789
-
Development by self-digestion: Molecular mechanisms and biological functions of autophagy
-
Levine B and Klionsky DJ. Development by self-digestion: molecular mechanisms and biological functions of autophagy. Dev Cell 6: 463-477, 2004.
-
(2004)
Dev Cell
, vol.6
, pp. 463-477
-
-
Levine, B.1
Klionsky, D.J.2
-
49
-
-
0344734108
-
Mortality patterns suggest lack of senescence in hydra
-
Martinez DE. Mortality patterns suggest lack of senescence in hydra. Exp Gerontol 33: 217-225, 1998.
-
(1998)
Exp Gerontol
, vol.33
, pp. 217-225
-
-
Martinez, D.E.1
-
50
-
-
0025044090
-
Effect of alpha-tocopherol and some metal chelators on lipofuscin accumulation in cultured neonatal rat cardiac myocytes
-
Marzabadi MR, Sohal RS, and Brunk UT. Effect of alpha-tocopherol and some metal chelators on lipofuscin accumulation in cultured neonatal rat cardiac myocytes. Anal Cell Pathol 2: 333-346, 1990.
-
(1990)
Anal Cell Pathol
, vol.2
, pp. 333-346
-
-
Marzabadi, M.R.1
Sohal, R.S.2
Brunk, U.T.3
-
51
-
-
0042691506
-
Autophagy genes are essential for dauer development and life-span extension in C. elegans
-
Melendez A, Talloczy Z, Seaman M, Eskelinen EL, Hall DH, and Levine B. Autophagy genes are essential for dauer development and life-span extension in C. elegans. Science 301: 1387-1391, 2003.
-
(2003)
Science
, vol.301
, pp. 1387-1391
-
-
Melendez, A.1
Talloczy, Z.2
Seaman, M.3
Eskelinen, E.L.4
Hall, D.H.5
Levine, B.6
-
52
-
-
0034967925
-
The ubiquitin-proteasome pathway and proteasome inhibitors
-
Myung J, Kim KB, and Crews CM. The ubiquitin-proteasome pathway and proteasome inhibitors. Med Res Rev 21: 245-273, 2001.
-
(2001)
Med Res Rev
, vol.21
, pp. 245-273
-
-
Myung, J.1
Kim, K.B.2
Crews, C.M.3
-
53
-
-
0029564967
-
Age-related changes in the lipofuscin accumulation of brain and heart
-
Nakano M, Oenzil F, Mizuno T, and Gotoh S. Age-related changes in the lipofuscin accumulation of brain and heart. Gerontology 41: 69-79, 1995.
-
(1995)
Gerontology
, vol.41
, pp. 69-79
-
-
Nakano, M.1
Oenzil, F.2
Mizuno, T.3
Gotoh, S.4
-
54
-
-
0037233423
-
Aging of cultured retinal pigment epithelial cells: Oxidative reactions, lipofuscin formation and blue light damage
-
Nilsson SE, Sundelin SP, Wihlmark U, and Brunk UT. Aging of cultured retinal pigment epithelial cells: oxidative reactions, lipofuscin formation and blue light damage. Doc Ophthalmol 106: 13-16, 2003.
-
(2003)
Doc Ophthalmol
, vol.106
, pp. 13-16
-
-
Nilsson, S.E.1
Sundelin, S.P.2
Wihlmark, U.3
Brunk, U.T.4
-
55
-
-
0142027772
-
Cardiac progenitor cells from adult myocardium: Homing, differentiation, and fusion after infarction
-
Oh H, Bradfute SB, Gallardo TD, Nakamura T, Gaussin V, Mishina Y, Pocius J, Michael LH, Behringer RR, Carry DJ, Entman ML, and Schneider MD. Cardiac progenitor cells from adult myocardium: homing, differentiation, and fusion after infarction. Proc Natl Acad Sci U S A 100: 12313-12318, 2003.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 12313-12318
-
-
Oh, H.1
Bradfute, S.B.2
Gallardo, T.D.3
Nakamura, T.4
Gaussin, V.5
Mishina, Y.6
Pocius, J.7
Michael, L.H.8
Behringer, R.R.9
Carry, D.J.10
Entman, M.L.11
Schneider, M.D.12
-
56
-
-
0015932795
-
Ageing of clones of mammalian cells
-
Orgel LE. Ageing of clones of mammalian cells. Nature 243: 441-445, 1973.
-
(1973)
Nature
, vol.243
, pp. 441-445
-
-
Orgel, L.E.1
-
57
-
-
0030897739
-
Genetic and functional changes in mitochondria associated with aging
-
Ozawa T. Genetic and functional changes in mitochondria associated with aging. Physiol Rev 77: 425-464, 1997.
-
(1997)
Physiol Rev
, vol.77
, pp. 425-464
-
-
Ozawa, T.1
-
58
-
-
0037448064
-
Prevention of oxidant-induced cell death by lysosomotropic iron chelators
-
Persson HL, Yu Z, Tirosh O, Eaton JW, and Brunk UT. Prevention of oxidant-induced cell death by lysosomotropic iron chelators. Free Radic Biol Med 34: 1295-1305, 2003.
-
(2003)
Free Radic Biol Med
, vol.34
, pp. 1295-1305
-
-
Persson, H.L.1
Yu, Z.2
Tirosh, O.3
Eaton, J.W.4
Brunk, U.T.5
-
59
-
-
0041885207
-
Linking oxidative stress and genetics of aging with p66Shc signaling and forkhead transcription factors
-
Purdom S and Chen QM. Linking oxidative stress and genetics of aging with p66Shc signaling and forkhead transcription factors. Biogerontology 4: 181-191, 2003.
-
(2003)
Biogerontology
, vol.4
, pp. 181-191
-
-
Purdom, S.1
Chen, Q.M.2
-
60
-
-
0036345047
-
Role of heme oxygenase-1 in the biogenesis of corpora amylacea
-
Sahlas DJ, Liberman A, and Schipper HM. Role of heme oxygenase-1 in the biogenesis of corpora amylacea. Biogerontology 3: 223-231, 2002.
-
(2002)
Biogerontology
, vol.3
, pp. 223-231
-
-
Sahlas, D.J.1
Liberman, A.2
Schipper, H.M.3
-
61
-
-
0024597761
-
Lysosomal integral membrane glycoproteins are expressed at high levels in the inclusion bodies of 1-cell disease fibroblasts
-
Sandoval IV, Chen JW, Yuan L, and August JT. Lysosomal integral membrane glycoproteins are expressed at high levels in the inclusion bodies of 1-cell disease fibroblasts. Arch Biochem Biophys 271: 157-167, 1989.
-
(1989)
Arch Biochem Biophys
, vol.271
, pp. 157-167
-
-
Sandoval, I.V.1
Chen, J.W.2
Yuan, L.3
August, J.T.4
-
62
-
-
0032874037
-
The effect of aging on pars compacta of the substantia nigra in rhesus monkey
-
Siddiqi ZA and Peters A. The effect of aging on pars compacta of the substantia nigra in rhesus monkey. J Neuropathol Exp Neurol 58: 903-920, 1999.
-
(1999)
J Neuropathol Exp Neurol
, vol.58
, pp. 903-920
-
-
Siddiqi, Z.A.1
Peters, A.2
-
63
-
-
0036628724
-
Role of oxidative stress and protein oxidation in the aging process
-
Sohal RS. Role of oxidative stress and protein oxidation in the aging process. Free Radic Biol Med 33: 37-44, 2002.
-
(2002)
Free Radic Biol Med
, vol.33
, pp. 37-44
-
-
Sohal, R.S.1
-
64
-
-
0031452173
-
Structure and physiological function of calpains
-
Sorimachi H, Ishiura S, and Suzuki K. Structure and physiological function of calpains. Biochem J 328: 721-732, 1997.
-
(1997)
Biochem J
, vol.328
, pp. 721-732
-
-
Sorimachi, H.1
Ishiura, S.2
Suzuki, K.3
-
65
-
-
0034881033
-
Oxidative stress and protein aggregation during biological aging
-
Squier TC. Oxidative stress and protein aggregation during biological aging. Exp Gerontol 36: 1539-1550, 2001.
-
(2001)
Exp Gerontol
, vol.36
, pp. 1539-1550
-
-
Squier, T.C.1
-
66
-
-
0035039021
-
Protein oxidation in aging and age-related diseases
-
Stadtman ER. Protein oxidation in aging and age-related diseases. Ann NY Acad Sci 928: 22-38, 2001.
-
(2001)
Ann NY Acad Sci
, vol.928
, pp. 22-38
-
-
Stadtman, E.R.1
-
68
-
-
12344251782
-
Inhibition of autophagy with 3-methyladenine results in impaired turnover of lysosomes and accumulation of lipofuscin-like material
-
Stroikin Y, Dalen H, Lööf S, and Terman A. Inhibition of autophagy with 3-methyladenine results in impaired turnover of lysosomes and accumulation of lipofuscin-like material. Eur J Cell Biol 83: 583-590, 2004.
-
(2004)
Eur J Cell Biol
, vol.83
, pp. 583-590
-
-
Stroikin, Y.1
Dalen, H.2
Lööf, S.3
Terman, A.4
-
69
-
-
0031812476
-
Lipofuscin accumulation of cultured retinal pigment epithelial cells reduces their phagocytic capacity
-
Sundelin S, Wihlmark U, Nilsson SEG, and Brunk UT. Lipofuscin accumulation of cultured retinal pigment epithelial cells reduces their phagocytic capacity. Curr Eye Res 17: 851-857, 1998.
-
(1998)
Curr Eye Res
, vol.17
, pp. 851-857
-
-
Sundelin, S.1
Wihlmark, U.2
Seg, N.3
Brunk, U.T.4
-
70
-
-
0037470501
-
The endocrine regulation of aging by insulin-like signals
-
Tatar M, Bartke A, and Antebi A. The endocrine regulation of aging by insulin-like signals. Science 299: 1346-1351, 2003.
-
(2003)
Science
, vol.299
, pp. 1346-1351
-
-
Tatar, M.1
Bartke, A.2
Antebi, A.3
-
71
-
-
0017233986
-
A morphometric study of the density of mitochondrial cristae in heart and liver of aging mice
-
Tate EL and Herbener GH. A morphometric study of the density of mitochondrial cristae in heart and liver of aging mice. J Gerontol 31: 129-134, 1976.
-
(1976)
J Gerontol
, vol.31
, pp. 129-134
-
-
Tate, E.L.1
Herbener, G.H.2
-
72
-
-
0347600946
-
Mitochondrial DNA mutations in human colonic crypt stem cells
-
Taylor RW, Barren MJ, Borthwick GM, Gospel A, Chinnery PF, Samuels DC, Taylor GA, Plusa SM, Needham SJ, Greaves LC, Kirkwood TB, and Turnbull DM. Mitochondrial DNA mutations in human colonic crypt stem cells. J Clin Invest 112: 1351-1360, 2003.
-
(2003)
J Clin Invest
, vol.112
, pp. 1351-1360
-
-
Taylor, R.W.1
Barren, M.J.2
Borthwick, G.M.3
Gospel, A.4
Chinnery, P.F.5
Samuels, D.C.6
Taylor, G.A.7
Plusa, S.M.8
Needham, S.J.9
Greaves, L.C.10
Kirkwood, T.B.11
Turnbull, D.M.12
-
73
-
-
18844425714
-
Role of compartmentalized redox-active iron on hydrogen peroxide-induced DNA damage and apoptosis
-
Tenopoulou M, Doulias PT, Barbouti A, Brunk UT, and Galaris D. Role of compartmentalized redox-active iron on hydrogen peroxide-induced DNA damage and apoptosis. Biochem J 387: 703-710, 2005.
-
(2005)
Biochem J
, vol.387
, pp. 703-710
-
-
Tenopoulou, M.1
Doulias, P.T.2
Barbouti, A.3
Brunk, U.T.4
Galaris, D.5
-
74
-
-
0035063178
-
Garbage catastrophe theory of aging: Imperfect removal of oxidative damage?
-
Terman A. Garbage catastrophe theory of aging: imperfect removal of oxidative damage? Redox Rep 6: 15-26, 2001.
-
(2001)
Redox Rep
, vol.6
, pp. 15-26
-
-
Terman, A.1
-
75
-
-
0032821609
-
Ceroid/lipofuscin-loaded human fibroblasts show increased susceptibility to oxidative stress
-
Terman A, Abrahamsson N, and Brunk UT. Ceroid/lipofuscin-loaded human fibroblasts show increased susceptibility to oxidative stress. Exp Gerontol 34: 755-770, 1999.
-
(1999)
Exp Gerontol
, vol.34
, pp. 755-770
-
-
Terman, A.1
Abrahamsson, N.2
Brunk, U.T.3
-
76
-
-
0032169551
-
Ceroid/lipofuscin formation in cultured human fibroblasts: The role of oxidative stress and lysosomal proteolysis
-
Terman A and Brunk UT. Ceroid/lipofuscin formation in cultured human fibroblasts: The role of oxidative stress and lysosomal proteolysis. Mech Ageing Dev 104: 277-291, 1998.
-
(1998)
Mech Ageing Dev
, vol.104
, pp. 277-291
-
-
Terman, A.1
Brunk, U.T.2
-
77
-
-
0032579473
-
On the degradability and exocytosis of ceroid/lipofuscin in cultured rat cardiac myocytes
-
Terman A and Brunk UT. On the degradability and exocytosis of ceroid/lipofuscin in cultured rat cardiac myocytes. Mech Ageing Dev 100: 145-156, 1998.
-
(1998)
Mech Ageing Dev
, vol.100
, pp. 145-156
-
-
Terman, A.1
Brunk, U.T.2
-
79
-
-
2342457124
-
Myocyte aging and mitochondrial turnover
-
Terman A and Brunk UT. Myocyte aging and mitochondrial turnover. Exp Gerontol 39: 701-705, 2004.
-
(2004)
Exp Gerontol
, vol.39
, pp. 701-705
-
-
Terman, A.1
Brunk, U.T.2
-
80
-
-
0032730787
-
Ceroid/lipofuscin-loaded human fibroblasts show decreased survival time and diminished autophagocytosis during amino acid starvation
-
Terman A, Dalen H, and Brunk UT. Ceroid/lipofuscin-loaded human fibroblasts show decreased survival time and diminished autophagocytosis during amino acid starvation. Exp Gerontol 34: 943-957, 1999.
-
(1999)
Exp Gerontol
, vol.34
, pp. 943-957
-
-
Terman, A.1
Dalen, H.2
Brunk, U.T.3
-
81
-
-
0042707790
-
Mitochondrial recycling and aging of cardiac myocytes: The role of autophagocytosis
-
Terman A, Dalen H, Eaton JW, Neuzil J, and Brunk UT. Mitochondrial recycling and aging of cardiac myocytes: The role of autophagocytosis. Exp Gerontol 38: 863-876, 2003.
-
(2003)
Exp Gerontol
, vol.38
, pp. 863-876
-
-
Terman, A.1
Dalen, H.2
Eaton, J.W.3
Neuzil, J.4
Brunk, U.T.5
-
82
-
-
3242715838
-
Aging of cardiac myocytes in culture: Oxidative stress, lipofuscin accumulation, and mitochondrial turnover
-
Terman A, Dalen H, Eaton JW, Neuzil J, and Brunk UT. Aging of cardiac myocytes in culture: Oxidative stress, lipofuscin accumulation, and mitochondrial turnover. Ann NY Acad Sci 1019: 70-77, 2004.
-
(2004)
Ann NY Acad Sci
, vol.1019
, pp. 70-77
-
-
Terman, A.1
Dalen, H.2
Eaton, J.W.3
Neuzil, J.4
Brunk, U.T.5
-
84
-
-
10844254688
-
Argyrophilic grain disease: A late-onset dementia with distinctive features among tauopathies
-
Tolnay M and Clavaguera F. Argyrophilic grain disease: a late-onset dementia with distinctive features among tauopathies. Neuropathology 24: 269-283, 2004.
-
(2004)
Neuropathology
, vol.24
, pp. 269-283
-
-
Tolnay, M.1
Clavaguera, F.2
-
85
-
-
0034663419
-
Somatic cell mutations: Can they provide a link between aging and cancer?
-
Turker MS. Somatic cell mutations: can they provide a link between aging and cancer? Mech Ageing Dev 117: 1-19, 2000.
-
(2000)
Mech Ageing Dev
, vol.117
, pp. 1-19
-
-
Turker, M.S.1
-
86
-
-
0030943224
-
Lipofuscin accumulation in cultured retinal pigment epithelial cells causes enhanced sensitivity to blue light irradiation
-
Wihlmark U, Wrigstad A, Roberg K, Nilsson SE, and Brunk UT. Lipofuscin accumulation in cultured retinal pigment epithelial cells causes enhanced sensitivity to blue light irradiation. Free Radic Biol Med 22: 1229-1234, 1997.
-
(1997)
Free Radic Biol Med
, vol.22
, pp. 1229-1234
-
-
Wihlmark, U.1
Wrigstad, A.2
Roberg, K.3
Nilsson, S.E.4
Brunk, U.T.5
-
87
-
-
0021867392
-
Lipofuscin accumulation and its prevention by vitamin e in nervous tissue: Quantitative analysis using snail buccal ganglia as a simple model system
-
Winstanley EK and Pentreath VW. Lipofuscin accumulation and its prevention by vitamin E in nervous tissue: quantitative analysis using snail buccal ganglia as a simple model system. Mech Ageing Dev 29: 299-307, 1985.
-
(1985)
Mech Ageing Dev
, vol.29
, pp. 299-307
-
-
Winstanley, E.K.1
Pentreath, V.W.2
-
89
-
-
0029587510
-
Early appearance of age-associated deterioration in mitochondrial function of diaphragm and heart in rats treated with doxorubicin
-
Yamada K, Sugiyama S, Kosaka K, Hayakawa M, and Ozawa T. Early appearance of age-associated deterioration in mitochondrial function of diaphragm and heart in rats treated with doxorubicin. Exp Gerontol 30: 581-593, 1995.
-
(1995)
Exp Gerontol
, vol.30
, pp. 581-593
-
-
Yamada, K.1
Sugiyama, S.2
Kosaka, K.3
Hayakawa, M.4
Ozawa, T.5
-
90
-
-
0141975261
-
The neuromelanin of human substantia nigra: Structure, synthesis and molecular behaviour
-
Zecca L, Zucca FA, Costi P, Tampellini D, Gatti A, Gerlach M, Riederer P, Fariello RG, Ito S, Gallorini M, and Sulzer D. The neuromelanin of human substantia nigra: structure, synthesis and molecular behaviour. J Neural Transm Suppl: 145-155, 2003.
-
(2003)
J Neural Transm
, Issue.SUPPL.
, pp. 145-155
-
-
Zecca, L.1
Zucca, F.A.2
Costi, P.3
Tampellini, D.4
Gatti, A.5
Gerlach, M.6
Riederer, P.7
Fariello, R.G.8
Ito, S.9
Gallorini, M.10
Sulzer, D.11
-
91
-
-
1842453324
-
Oxidative stress signalling in Alzheimer's disease
-
Zhu X, Raina AK, Lee HG, Casadesus G, Smith MA, and Perry G. Oxidative stress signalling in Alzheimer's disease. Brain Res 1000: 32-39, 2004.
-
(2004)
Brain Res
, vol.1000
, pp. 32-39
-
-
Zhu, X.1
Raina, A.K.2
Lee, H.G.3
Casadesus, G.4
Smith, M.A.5
Perry, G.6
-
92
-
-
0037010295
-
Age-related decline in neurogenesis: Old cells or old environment?
-
Zitnik G and Martin GM. Age-related decline in neurogenesis: old cells or old environment? J Neurosci Res 70: 258-263, 2002.
-
(2002)
J Neurosci Res
, vol.70
, pp. 258-263
-
-
Zitnik, G.1
Martin, G.M.2
-
93
-
-
9244242006
-
The neuromelanin of human substantia nigra: Physiological and pathogenic aspects
-
Zucca FA, Giaveri G, Gallorini M, Albertini A, Toscani M, Pezzoli G, Lucius R, Wilms H, Sulzer D, Ito S, Wakamatsu K, and Zecca L. The neuromelanin of human substantia nigra: physiological and pathogenic aspects. Pigment Cell Res 17: 610-617, 2004.
-
(2004)
Pigment Cell Res
, vol.17
, pp. 610-617
-
-
Zucca, F.A.1
Giaveri, G.2
Gallorini, M.3
Albertini, A.4
Toscani, M.5
Pezzoli, G.6
Lucius, R.7
Wilms, H.8
Sulzer, D.9
Ito, S.10
Wakamatsu, K.11
Zecca, L.12
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