Promotion of prostatic metastatic migration towards human bone marrow stoma by Omega 6 and its inhibition by Omega 3 PUFAs

British Journal of Cancer

Volumn 94, Issue 6, 2006, Pages 842-853

  Brown, M D ^a   Hart, C A ^a   Gazi, E ^a   Bagley, S ^a   Clarke, N W ^a,b  

^a CHRISTIE HOSPITAL   (United Kingdom)

^b HOPE HOSPITAL   (United Kingdom)

Author keywords

Arachidonic acid; Bone marrow; Metastasis; Omega 3; Omega 6; Prostate cancer

Indexed keywords

ARACHIDONIC ACID; CYCLOOXYGENASE 2 INHIBITOR; DOCOSAHEXAENOIC ACID; ICOSAPENTAENOIC ACID; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; PROSTAGLANDIN E2;

ADIPOCYTE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BONE MARROW METASTASIS; CANCER CELL; CANCER CELL CULTURE; CANCER INVASION; CELL INVASION; COCULTURE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EPITHELIUM CELL; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; INFRARED SPECTROSCOPY; MALE; PRIORITY JOURNAL; PROSTATE CANCER; STROMA; STROMA CELL; VOLUMETRY;

ARACHIDONIC ACID; BONE MARROW NEOPLASMS; CELL MOVEMENT; DOSE-RESPONSE RELATIONSHIP, DRUG; FATTY ACIDS, OMEGA-3; FATTY ACIDS, OMEGA-6; HUMANS; MALE; NEOPLASM INVASIVENESS; PROSTATIC NEOPLASMS; RISK FACTORS; TUMOR CELLS, CULTURED;

EID: 33645296034     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6603030     Document Type: Article

References (56)

1. Augustsson K, Michaud DS, Rimm EB, Leitzmann MF, Stampfer MJ, Willett WC, Giovannucci E (2003) A prospective study of intake of fish and marine fatty acids and prostate cancer. Cancer Epidemiol Biomarkers Prev 12: 64-67
2. Brockman JA, Gupta RA, Dubois RN (1998) Activation of PPARgamma leads to inhibition of anchorage-independent growth of human colorectal cancer cells. Gastroenterology 115: 1049-1055
3. Compston JE (2002) Bone marrow and bone: a functional unit. J Endocrinol 173: 387-394
4. Coutinho LH, Gilleece MH, de Wynter E, Will A, Testa NG (1993) Clonal and long-term cultures using human bone marrow. In Haemopoiesis: A Practical Approach Testa NGMG (ed), pp 75-106. Oxford: Oxford University Press
5. Dandekar DS, Lokeshwar BL (2004) Inhibition of cyclooxygenase (COX)-2 expression by Tet-inducible COX-2 antisense cDNA in hormone-refractory prostate cancer significantly slows tumor growth and improves efficacy of chemotherapeutic drugs. Clin Cancer Res 10: 8037-8047
6. Denizot Y, Desplat V, Dulery C, Trimoreau F, Praloran V (1999) Arachidonic acid and freshly isolated human bone marrow mononuclear cells. Mediators Inflamm 8: 31-35
7. Denizot Y, Dulery C, Trimoreau F, Desplat V, Praloran V (1998) Arachidonic acid and human bone marrow stromal cells. Biochim Biophys Acta 1402: 209-215
8. Dexter TM, Allen TD, Lajtha LG (1977) Conditions controlling the proliferation of haemopoietic stem cells in vitro. J Cell Physiol 91: 335-344
9. Faas FH, Dang AQ, White J, Schaefer RF, Johnson DE (2003) Decreased prostatic arachidonic acid in human prostatic carcinoma. BJU Int 92: 551-554
10. Gao X, Grignon DJ, Chbihi T, Zacharek A, Chen YQ, Sakr W, Porter AT, Crissman JD, Pontes JE, Powell IJ, Honn KV (1995) Elevated 12-lipoxygenase mRNA expression correlates with advanced stage and poor differentiation of human prostate cancer. Urology 46: 227-237
11. George NJ (1988) Natural history of localised prostatic cancer managed by conservative therapy alone. Lancet 1: 494-497
12. Ghosh J (2004) Rapid induction of apoptosis in prostate cancer cells by selenium: reversal by metabolites of arachidonate 5-lipoxygenase. Biochem Biophys Res Commun 315: 624-635
13. Giovannucci E, Rimm EB, Colditz GA, Stampfer MJ, Ascherio A, Chute CC, Willett WC (1993) A prospective study of dietary fat and risk of prostate cancer. J Natl Cancer Inst 85: 1571-1579
14. Haenszel W (1961) Cancer mortality among the foreign-born in the United States. J Natl Cancer Inst 26: 37-132
15. Haenszel W, Kurihara M (1968) Studies of Japanese migrants. I. Mortality from cancer and other diseases among Japanese in the United States. J Natl Cancer Inst 40: 43-68
16. Harrison N, Abhyankar B (2005) The mechanism of action of omega-3 fatty acids in secondary prevention post-myocardial infarction. Curr Med Res Opin 21: 95-100
17. Hart CA, Brown M, Bagley S, Sharrard M, Clarke NW (2005) Invasive characteristics of human prostatic epithelial cells: understanding the metastatic process. Br J Cancer 92: 503-512
18. Hart CA, Scott LJ, Bagley S, Bryden AA, Clarke NW, Lang SH (2002) Role of proteolytic enzymes in human prostate bone metastasis formation: in vivo and in vitro studies. Br J Cancer 86: 1136-1142
19. Holub DJ, Holub BJ (2004) Omega-3 fatty acids from fish oils and cardiovascular disease. Mol Cell Biochem 263: 217-225
20. Honn KV, Tang DG, Gao X, Butovich IA, Liu B, Timar J, Hagmann W (1994) 12-lipoxygenases and 12(S)-HETE: role in cancer metastasis. Cancer Metastasis Rev 13: 365-396
21. Hughes-Fulford M, Tjandrawinata RR, Li CF, Sayyah S (2005) Arachidonic acid, an omega-6 fatty acid, induces cytoplasmic phospholipase A2 in prostate carcinoma cells. Carcinogenesis 26: 1520-1526
22. Kaighn ME, Narayan KS, Ohnuki Y, Lechner JF, Jones LW (1979) Establishment and characterization of a human prostatic carcinoma cell line (PC-3). Invest Urol 17: 16-23
23. Karmali RA, Reichel P, Cohen LA, Terano T, Hirai A, Tamura Y, Yoshida S (1987) The effects of dietary omega-3 fatty acids on the DU-145 transplantable human prostatic tumor. Anticancer Res 7: 1173-1179
24. Krotz F, Schiele TM, Klauss V, Sohn HY (2005) Selective COX-2 inhibitors and risk of myocardial infarction. J Vasc Res 42: 312-324
25. Lang SH, Clarke NW, George NJ, Allen TD, Testa NG (1998) Interaction of prostate epithelial cells from benign and malignant tumor tissue with bone-marrow stroma. Prostate 34: 203-213
26. Lang SH, Clarke NW, George NJ, Testa NG (1997) Primary prostatic epithelial cell binding to human bone marrow stroma and the role of alpha2betal integrin. Clin Exp Metastasis 15: 218-227
27. Lanier AP, Bender TR, Blot WJ, Fraumeni Jr JF, Hurlburt WB (1976) Cancer incidence in Alaska natives. Int J Cancer 18: 409-412
28. Lanier AP, Kelly JJ, Smith B, Harpster AP, Tanttila H, Amadon C, Beckworth D, Key C, Davidson AM (1996) Alaska Native cancer update: incidence rates 1989-1993. Cancer Epidemiol Biomarkers Prev 5: 749-751
29. Luo C, He ML, Bohlin L (2005) Is COX-2 a perpetrator or a protector? Selective COX-2 inhibitors remain controversial. Acta Pharmacol Sin 26: 926-933
30. Mamalakis G, Kafatos A, Kalogeropoulos N, Andrikopoulos N, Daskalopulos G, Kranidis A (2002) Prostate cancer vs hyperplasia: relationships with prostatic and adipose tissue fatty acid composition. Prostaglandins Leukot Essent Fatty Acids 66: 467-477
31. Marchioli R, Barzi F, Bomba E, Chieffo C, Di Gregorio D, Di Mascio R, Franzosi MG, Geraci E, Levantesi G, Maggioni AP, Mantini L, Marfisi RM, Mastrogiuseppe G, Mininni N, Nicolosi GL, Santini M, Schweiger C, Tavazzi L, Tognoni G, Tucci C, Valagussa F (2002) Early protection against sudden death by n-3 polyunsaturated fatty acids after myocardial infarction: time-course analysis of the results of the Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico (GISSI)-Prevenzione. Circulation 105: 1897-1903
32. Meunier P, Aaron J, Edouard C, Vignon G (1971) Osteoporosis and the replacement of cell populations of the marrow by adipose tissue. A quantitative study of 84 iliac bone biopsies. Clin Orthop Relat Res 80: 147-154
33. Moretti RM, Montagnani Marelli M, Sala A, Motta M, Limonta P (2004) Activation of the orphan nuclear receptor RORalpha counteracts the proliferative effect of fatty acids on prostate cancer cells: crucial role of 5-lipoxygenase. Int J Cancer 112: 87-93
34. Mueller E, Sarraf P, Tontonoz P, Evans RM, Martin KJ, Zhang M, Fletcher C, Singer S, Spiegelman BM (1998) Terminal differentiation of human breast cancer through PPAR gamma. Mol Cell 1: 465-470
35. Nie D, Hillman GG, Geddes T, Tang K, Pierson C, Grignon DJ, Honn KV (1998) Platelet-type 12-lipoxygenase in a human prostate carcinoma stimulates angiogenesis and tumor growth. Cancer Res 58: 4047-4051
36. Norrish AE, Skeaff CM, Arribas GL, Sharpe SJ, Jackson RT (1999) Prostate cancer risk and consumption of fish oils: a dietary biomarker-based case-control study. Br J Cancer 81: 1238-1242
37. O'Flaherty JT, Rogers LC, Chadwell BA, Owen JS, Rao A, Cramer SD, Daniel LW (2002) 5(S)-Hydroxy-6,8,11,14-E,Z,Z,Z-eicosatetraenoate stimulates PC3 cell signaling and growth by a receptor-dependent mechanism. Cancer Res 62: 6817-6819
38. Parkin DM, Bray F, Ferlay J, Pisani P (2005) Global cancer statistics, 2002. CA Cancer J Clin 55: 74-108
39. Patel MI, Subbaramaiah K, Du B, Chang M, Yang P, Newman RA, Cordon-Cardo C, Thaler HT, Dannenberg AJ (2005) Celecoxib inhibits prostate cancer growth: evidence of a cyclooxygenase-2-independent mechanism. Clin Cancer Res 11: 1999-2007
40. Rahimi N, Saulnier R, Nakamura T, Park M, Elliott B (1994) Role of hepatocyte growth factor in breast cancer: a novel mitogenic factor secreted by adipocytes. DNA Cell Biol 13: 1189-1197
41. Rasband W (2005) ImageJ. Bethesda, Maryland, USA: US National Institutes of Health
42. Rose DP (1997) Effects of dietary fatty acids on breast and prostate cancers: evidence from in vitro experiments and animal studies. Am J Clin Nutr 66: 1513S-1522S
43. Rose DP, Connolly JM (1999) Omega-3 fatty acids as cancer chemopreventive agents. Pharmacol Ther 83: 217-244
44. Rozman C, Feliu E, Berga L, Reverter JC, Climent C, Ferran MJ (1989) Age-related variations of fat tissue fraction in normal human bone marrow depend both on size and number of adipocytes: a stereological study. Exp Hematol 17: 34-37
45. Scott LJ, Clarke NW, Sharrard MS, George NJ, Lang SH (2000) Invasive phenotype of primary human prostatic epithelial cells. Prostate Cancer Prostatic Dis 3: 1136-1142
46. Shappell SB, Boeglin WE, Olson SJ, Kasper S, Brash AR (1999) 15-lipoxygenase-2 (15-LOX-2) is expressed in benign prostatic epithelium and reduced in prostate adenocarcinoma. Am J Pathol 155: 235-245
47. Shappell SB, Gupta RA, Manning S, Whitehead R, Boeglin WE, Schneider C, Case T, Price J, Jack GS, Wheeler TM, Matusik RJ, Brash AR, Dubois RN (2001) 15S-Hydroxyeicosatetraenoic acid activates peroxisome proliferator-activated receptor gamma and inhibits proliferation in PC3 prostate carcinoma cells. Cancer Res 61: 497-503
48. Snowdon DA, Phillips RL, Choi W (1984) Diet, obesity, and risk of fatal prostate cancer. Am J Epidemiol 120: 244-250
49. Sumida T (1965) Clinical and experimental study on fatty acid composition of bone marrow lipid in hematologic disorders. Acta Med Nagasaki 9: 222-241
50. Sun YX, Wang J, Shelburne CE, Lopatin DE, Chinnaiyan AM, Rubin MA, Pienta KJ, Taichman RS (2003) Expression of CXCR4 and CXCL12 (SDF-1) in human prostate cancers (PCa) in vivo. J Cell Biochem 89: 462-473
51. Taichman RS, Cooper C, Keller ET, Pienta KJ, Taichman NS, McCauley LK (2002) Use of the stromal cell-derived factor-1/CXCR4 pathway in prostate cancer metastasis to bone. Cancer Res 62: 1832-1837
52. Terry P, Lichtenstein P, Feychting M, Ahlbom A, Wolk A (2001) Fatty fish consumption and risk of prostate cancer. Lancet 357: 1764-1766
53. Tokuda Y, Satoh Y, Fujiyama C, Toda S, Sugihara H, Masaki Z (2003) Prostate cancer cell growth is modulated by adipocyte-cancer cell interaction. BJU Int 91: 716-720
54. Toogood IR, Dexter TM, Allen TD, Suda T, Lajtha LG (1980) The development of a liquid culture system for the growth of human bone marrow. Leuk Res 4: 449-461
55. Wynder EL, Fujita Y, Harris RE, Hirayama T, Hiyama T (1991) Comparative epidemiology of cancer between the United States and Japan. A second look. Cancer 67: 746-763
56. Zangani D, Darcy KM, Shoemaker S, Ip MM (1999) Adipocyte-epithelial interactions regulate the in vitro development of normal mammary epithelial cells. Exp Cell Res 247: 399-409