Differential effects of delivery of omega-3 fatty acids to human cancer cells by low-density lipoproteins versus albumin

Clinical Cancer Research

Volumn 10, Issue 24, 2004, Pages 8275-8283

  Edwards, Iris J ^a   Berquin, Isabelle M ^a   Sun, Haiguo ^a   O'Flaherty, Joseph T ^a   Daniel, Larry W ^a   Thomas, Michael J ^a   Rudel, Lawrence L ^a   Wylde, Robert L ^a   Chen, Yong Q ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; CHOLESTEROL; FISH OIL; LINOLEIC ACID; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLETHANOLAMINE; PHOSPHOLIPID; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL PROLIFERATION; CERCOPITHECIDAE; CONTROLLED STUDY; DNA MICROARRAY; DNA SYNTHESIS; DRUG DELIVERY SYSTEM; DRUG EFFECT; FATTY ACID TRANSPORT; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; LIPID COMPOSITION; LIPID DIET; LIPID TRANSPORT; MALE; MOLECULAR MECHANICS; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR UPREGULATION; STATISTICAL SIGNIFICANCE; TRANSCRIPTION REGULATION;

ALBUMINS; ANIMALS; APOPTOSIS; BREAST NEOPLASMS; CELL PROLIFERATION; CERCOPITHECUS AETHIOPS; CHOLESTEROL; DRUG DELIVERY SYSTEMS; FATTY ACIDS, OMEGA-3; FEMALE; FISH OILS; GENE EXPRESSION PROFILING; HUMANS; LINOLEIC ACID; LIPOPROTEINS, LDL; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHOSPHATIDYLCHOLINES; PHOSPHATIDYLETHANOLAMINES; PROSTATIC NEOPLASMS; TRIGLYCERIDES; TUMOR CELLS, CULTURED;

EID: 11144247920     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-04-1357     Document Type: Article

References (48)

1. Sasaki S, Horacsek M, Kesteloot H. An ecological study of the relationship between dietary fat intake and breast cancer mortality. Prev Med 1993;22:187-202.
2. Kaizer L, Boyd NF, Kriukov V, Tritchler D. Fish consumption and breast cancer risk: an ecological study. Nutr Cancer 1989;12:61-8.
3. Hursting SD, Thornquist M, Henderson MM. Types of dietary fat and the incidence of cancer at five sites. Prev Med 1990;19:242-53.
4. Augustus AS, Kako Y, Yagyu H, Goldberg IJ. Routes of FA delivery to cardiac muscle: modulation of lipoprotein lipolysis alters uptake of TG-derived FA. Am J Physiol Endocrinol Metab 2003;284:E331-9.
5. Gal D, MacDonald PC, Porter JC, Simpson ER. Cholesterol metabolism in cancer cells in monolayer culture. III. Low-density lipoprotein metabolism. Int J Cancer 1981;28:315-9.
6. Grammatikos SI, Subbaiah PV, Victor TA, Miller WM. n-3 and n-6 FA processing and growth effects in neoplastic and non-cancerous human mammary epithelial cell lines. Br J Cancer 1994;70:219-27.
7. Rose DP, Connolly JM. Stimulation of growth of human breast cancer cell lines in culture by linoleic acid. Biochem Biophys Res Commun 1989;164:277-83.
8. Rose DP, Connolly JM. Effects of fatty acids and inhibitors of eicosanoid synthesis on the growth of a human breast cancer cell line in culture. Cancer Res 1990;50:7139-44.
9. Connolly JM, Rose DP. Effects of fatty acids on invasion through reconstituted basement membrane ('Matrige') by a human breast cancer cell line. Cancer Lett 1993;75:137-42.
10. Rudel LL, Parks JS, Sawyer JK. Compared with dietary monoun-saturated and saturated fat, polyunsaturated fat protects African green monkeys from coronary artery atherosclerosis. Arterioscler Thromb Vasc Biol 1995;15:2101-10.
11. Rudel LL, Johnson FL, Sawyer JK, Wilson MS, Parks JS. Dietary polyunsaturated fat modifies low-density lipoproteins and reduces atherosclerosis of nonhuman primates with high and low diet responsiveness. Am J Clin Nutr 1995;62:463S-70S.
12. Rudel LL, Parks JS, Hedrick CC, Thomas M, Williford K. Lipoprotein and cholesterol metabolism in diet-induced coronary artery atherosclerosis in primates. Role of cholesterol and fatty acids. Prog Lipid Res 1998;37:353-70.
13. Rumsey SC, Galeano NF, Arad Y, Deckelbaum RJ. Cryopreservation with sucrose maintains normal physical and biological properties of human plasma low density lipoproteins. J Lipid Res 1992;33:1551-61.
14. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Polin phenol reagent. J Biol Chem 1951;193:265-75.
15. Parks JS, Gebre AK. Studies on the effect of dietary fish oil on the physical and chemical properties of low density lipoproteins in cynomolgus monkeys. J Lipid Res 1991;32:305-15.
16. Ishikawa TT, MacGee J, Morrison JA, Glueck CJ. Quantitative analysis of cholesterol in 5 to 20 microliter of plasma. J Lipid Res 1974;15:286-91.
17. DeLong CJ, Baker PR, Samuel M, Cui Z, Thomas MJ. Molecular species composition of rat liver phospholipids by ESI-MS/MS: the effect of chromatography. J Lipid Res 2001;42:1959-68.
18. Muller PY, Janovjak H, Miserez AR, Dobbie Z. Processing of gene expression data generated by quantitative real-time RT-PCR. Biotechniques 2002;32:1372-4, 6, 8-9.
19. Hughes-Fulford M, Chen Y, Tjandrawinata RR. Fatty acid regulates gene expression and growth of human prostate cancer PC-3 cells. Carcinogenesis (Lond) 2001;22:701-7.
20. Stranzl A, Schmidt H, Winkler R, Kostner GM. Low-density lipoprotein receptor mRNA in human breast cancer cells: influence by PKC modulators. Breast Cancer Res Treat 1997;42:195-205.
21. Rose DP. Effects of dietary fatty acids on breast and prostate cancers: evidence from in vitro experiments and animal studies. Am J Clin Nutr 1997;66:1513S-22S.
22. Goodman DS. Cholesterol ester metabolism. Physiol Rev 1965;45:747-839.
23. Batetta B, Mulas MF, Sanna F, et al. Role of cholesterol ester pathway in the control of cell cycle in human aortic smooth muscle cells. FASEB J 2003;17:746-8.
24. Simonsen N, van't Veer P, Strain JJ, et al. Adipose tissue omega-3 and omega-6 fatty acid content and breast cancer in the EURAMIC study. European Community Multicenter Study on Antioxidants, Myocardial Infarction, and Breast Cancer. Am J Epidemiol 1998;147:342-52.
25. Hagve TA, Christophersen BO. Effect of dietary fats on arachidonic acid and eicosapentaenoic acid biosynthesis and conversion to C22 fatty acids in isolated rat liver cells. Biochim Biophys Acta 1984;796:205-17.
26. Gooch JL, Yee D. Strain-specific differences in formation of apoptotic DNA ladders in MCF-7 breast cancer cells. Cancer Lett 1999;144:31-7.
27. Burow ME, Weldon CB, Tang Y, et al. Differences in susceptibility to tumor necrosis factor alpha-induced apoptosis among MCF-7 breast cancer cell variants. Cancer Res 1998;58:4940-6.
28. Chamras H, Ardashian A, Heber D, Glaspy JA. Fatty acid modulation of MCF-7 human breast cancer cell proliferation, apoptosis and differentiation. J Nutr Biochem 2002;13:711-6.
29. Chang WL, Chapkin RS, Lupton JR. Fish oil blocks azoxymethane-induced rat colon tumorigenesis by increasing cell differentiation and apoptosis rather than decreasing cell proliferation. J Nutr 1998;128:491-7.
30. Hong MY, Chapkin RS, Davidson LA, et al. Fish oil enhances targeted apoptosis during colon tumor initiation in part by downregulating Bcl-2. Nutr Cancer 2003;46:44-51.
31. Heimli H, Finstad HS, Drevon CA. Necrosis and apoptosis in lymphoma cell lines exposed to eicosapentaenoic acid and antioxidants. Lipids 2001;36:613-21.
32. Heimli H, Giske C, Naderi S, Drevon CA, Hollung K. Eicosapentaenoic acid promotes apoptosis in Ramos cells via activation of caspase-3 and -9. Lipids 2002;37:797-802.
33. Chen ZY, Istfan NW. Docosahexaenoic acid is a potent inducer of apoptosis in HT-29 colon cancer cells. Prostaglandins Leukot Essent Fatty Acids 2000;63:301-8.
34. Narayanan BA, Narayanan NK, Reddy BS. Docosahexaenoic acid regulated genes and transcription factors inducing apoptosis in human colon cancer cells. Int J Oncol 2001;19:1255-62.
35. Yamamoto D, Kiyozuka Y, Adachi Y, et al. Synergistic action of apoptosis induced by eicosapentaenoic acid and TNP-470 on human breast cancer cells. Breast Cancer Res Treat 1999;55:149-60.
36. Feldman RJ, Sementchenko VI, Gayed M, Fraig MM, Watson DK. Pdef expression in human breast cancer is correlated with invasive potential and altered gene expression. Cancer Res 2003;63:4626-31.
37. Oettgen P, Finger E, Sun Z, et al. PDEF, a novel prostate epithelium-specific ets transcription factor, interacts with the androgen receptor and activates prostate-specific antigen gene expression. J Biol Chem 2000;275:1216-25.
38. Chen H, Nandi AK, Li X, Bieberich CJ. NKX-3.1 interacts with prostate-derived Ets factor and regulates the activity of the PSA promoter. Cancer Res 2002;62:338-40.
39. Reddy BS, Cohen LA, McCoy GD, et al. Nutrition and its relationship to cancer. Adv Cancer Res 1980;32:237-345.
40. Jurkowski JJ, Cave WT Jr. Dietary effects of menhaden oil on the growth and membrane lipid composition of rat mammary tumors. J Natl Cancer Inst (Bethesda) 1985;74:1145-50.
41. Braden LM, Carroll KK. Dietary polyunsaturated fat in relation to mammary carcinogenesis in rats. Lipids 1986;21:285-8.
42. Gabor H, Hillyard LA, Abraham S. Effect of dietary fat on growth kinetics of transplantable mammary adenocarcinoma in BALB/c mice. J Natl Cancer Inst (Bethesda) 1985;74:1299-305.
43. Rose DP, Hatala MA, Connolly JM, Rayburn J. Effect of diets containing different levels of linoleic acid on human breast cancer growth and lung metastasis in nude mice. Cancer Res 1993;53:4686-90.
44. Rose DP, Connolly JM. Effects of dietary omega-3 fatty acids on human breast cancer growth and metastases in nude mice. J Natl Cancer Inst (Bethesda) 1993;85:1743-7.
45. Rose DP, Connolly JM, Rayburn J, Coleman M. Influence of diets containing eicosapentaenoic or docosahexaenoic acid on growth and metastasis of breast cancer cells in nude mice. J Natl Cancer Inst (Bethesda) 1995;87:587-92.
46. Rose DP, Connolly JM, Coleman M. Effect of omega-3 fatty acids on the progression of metastases after the surgical excision of human breast cancer cell solid tumors growing in nude mice. Clin Cancer Res 1996;2:1751-6.
47. Hardman WE, Avula CP, Fernandes G, Cameron IL. Three percent dietary fish oil concentrate increased efficacy of doxorubicin against MDA-MB 231 breast cancer xenografts. Clin Cancer Res 2001;7:2041-9.
48. Shao Y, Pardini L, Pardini RS. Dietary menhaden oil enhances mitomycin C antitumor activity toward human mammary carcinoma MX-1. Lipids 1995;30:1035-45.