Regulation of tumor angiogenesis by dietary fatty acids and eicosanoids

Nutrition and Cancer

Volumn 37, Issue 2, 2000, Pages 119-127

  Rose, D P ^a   Connolly, J M ^a  

^a AMERICAN HEALTH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS INHIBITOR; ARACHIDONIC ACID; BASIC FIBROBLAST GROWTH FACTOR; DOCOSAHEXAENOIC ACID; FATTY ACID; ICOSANOID; INDOMETACIN; LEUKOTRIENE B4; LEUKOTRIENE C4; LINOLEIC ACID; LIPOXYGENASE; OMEGA 6 FATTY ACID; PROSTACYCLIN; PROSTAGLANDIN D2; PROSTAGLANDIN E2; PROSTAGLANDIN F2 ALPHA; PROSTAGLANDIN SYNTHASE; PROSTANOID; THROMBOXANE A2; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL MODEL; BREAST CARCINOMA; CANCER GROWTH; FAT INTAKE; FATTY ACID METABOLISM; METASTASIS; MOUSE; NONHUMAN; NUDE MOUSE; PROGNOSIS; REGULATORY MECHANISM; REVIEW; TUMOR GROWTH; TUMOR VASCULARIZATION;

EID: 0033637473     PISSN: 01635581     EISSN: None     Source Type: Journal    
DOI: 10.1207/S15327914NC372_1     Document Type: Review

References (115)

1. What is the evidence that tumors are angiogenesis dependent?
2. Tumor angiogenesis: Review of current applications in tumor prognostication
3. Prognostic value of p53 expression in early-stage breast carcinoma compared with tumour angiogenesis, epidermal growth factor receptor, c-erb B-2, cathepsin D, DNA ploidy, parameters of cell kinetics and conventional features
4. Quantitation and prognostic value of breast cancer angiogenesis: Comparison of microvessel density, Chalkley count, and computer image analysis
5. Angiognnesis as a predictor of long-term survival for patients with node-negative breast cancer
6. Relation of neovascularisation to metastasis of non-small-cell lung cancer
7. The prognostic significance of tumor vascularity in intermediate-thickness (0.76-4.0 mm thick) skin melanoma
8. The significance of atypical vessels and neovascularization in cervical neoplasia
9. Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma
10. Vascular density is a predictor of cancer-specific survival in prostatic carcinoma
11. Prospective study of intratumoral microvessel density, p53 expression and survival in colorectal cancer
12. Angiogenesis and risk of breast cancer in women with fibrocystic disease
13. Microvessel quantification as a measure of angiogenic activity in benign breast tissue lesions: Marker for precancerous disease?
14. Vascularity of proliferative breast disease carcinoma in situ correlates with histological features
15. Predictors of pathologic stage in prostatic carcinoma. The role of neovascularity
16. Tumour angiogenesis in latent prostatic carcinoma
17. Angiogenesis is associated with vascular endothelial growth factor expression in cervical intraepithelial neoplasia
18. Inhibitory effect of a primary tumor on metastasis
19. Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma
20. Endostatin: An endogenous inhibitor of angiogenesis and tumor growth
21. Association of vascular endothelial growth factor expression with tumor angiogenesis and with early relapse in primary breast cancer
22. Vascular endothelial growth factor (VEGF) expression in prostate cancer and benign prostatic hyperplasia
23. Association of vascular endothelial growth factor expression with intratumoral microvessel density and tumour cell proliferation in human epidermoid lung carcinoma
24. Vascular endothelial growth factor is a predictor of relapse and stage progression in superficial bladder cancer
25. Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in endometrial carcinoma
26. Expression of vascular endothelial growth factor and its receptors fit and KDR in ovarian carcinoma
27. Vascular endothelial growth factor and lymph node metastasis in primary lung cancer
28. Vascular permeability factor (vascular endothelial growth factor) expression and angiogenesis in patients with ductal carcinoma in situ of the breast
29. Fibroblast growth factors: At the heart of angiogenesis
30. Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro
31. Synergistic effect of vascular endothelial growth factor and basic fibroblast growth factor on angiogenesis in vivo
32. 1, platelet-derived endothelial cell growth factor, placenta growth factor, and pleiotrophin in human primary breast cancer and its relation to angiogenesis
33. Vascular endothelial growth factor is induced in response to transforming growth factor-β in fibroblastic and epithelial cells
34. 1 regulation of VEGF production by breast cancer cells
35. Regulation of vascular endothelial growth factor expression in human colon cancer by insulin-like growth factor-I
36. Enhancement of tumor growth and vascular density by transfection of vascular endothelial cell growth factor into MCF-7 human breast carcinoma cells
37. Expression of vascular permeability factor/vascular endothelial growth factor by melanoma cells increases tumor growth, angiogenesis, and experimental metastasis
38. Vascular endothelial growth factor is essential for initial but not continued in vivo growth of human breast carcinoma cells
39. A comparison of the expression of the malignant phenotype in two androgen-independent human prostate cancer cell lines after orthotopic implantation in nude mice
40. Angiogenesis in two human prostate cancer cell lines with differing metastatic potential when growing as solid tumors in nude mice
41. Expression of angiogenesis-related genes and progression of human ovarian carcinomas in nude mice
42. Dietary fat and breast cancer metastasis by human tumor xenografts
43. Effect of dietary fat on human breast cancer growth and metastasis in nude mice
44. Effect of diets containing different levels of linoleic acid on human breast cancer growth and lung metastasis in nude mice
45. Effects of linoleic acid on the growth and metastasis of two human breast cancer cell lines in nude mice and the invasive capacity of these cell lines in vitro
46. Effects of reduced dietary linoleic acid intake, alone or combined with an algal source of docosahexaenoic acid, on MDA-MB-231 breast cancer cell growth and apoptosis in nude mice
47. Influence of diets containing different levels of eicosapentaenoic or docosahexaenoic acid on the growth and metastasis of human breast cancer cells in nude mice
48. Effect of ω-3 fatty acids on the progression of metastases after the surgical excision of human breast cancer cell solid tumors growing in nude mice
49. Antiangiogenicity of docosahexaenoic acid and its role in the suppression of breast cancer cell growth in nude mice
50. Regulation of prostaglandin synthase-1 and prostaglandin synthase-2
51. Prostaglandin synthase 2
52. Cyclooxygenase-2 induction and transforming growth factor-β growth inhibition in rat intestinal epithelial cells
53. Induction of cyclooxygenase-2 in rat gastric epithelial cell line by epiregulin and basic fibroblast growth factor
54. Transcription of cyclooxygenase-2 is enhanced in transformed mammary epithelial cells
55. Dietary fatty acids and human breast cancer cell growth, invasion, and metastasis
56. Dietary linoleic acid-stimulated human breast cancer cell growth and metastasis in nude micea and their suppression by indomethacin, a cyclooxygenase inhibitor
57. Differential expression and regulation of cyclooxygenase-1 and -2 in two human breast cancer cell lines
58. The association between a mutated ras gene and cyclooxygenase-2 expression in human breast cancer cell lines
59. Effects of fatty acids and inhibitors of eicosanoid synthesis on the growth of a human breast cancer cell line in culture
60. Neovasculogenic ability of prostaglandins, growth factors and synthetic chemoattractants
61. 1 and copper in angiogenesis
62. 2 and angiogenesis
63. 4 stimulates angiogenesis in bovine carotid artery endothelial cells in vitro
64. Regulation of the steps of angiogenesis by human head and neck squamous cell carcinomas
65. Cyclooxygenase regulates angiogenesis induced by colon cancer cells
66. Physiological and pathophysiological roles of eicosanoids in the microcirculation
67. Prostaglandins and local circulatory control
68. The endothelial cells of large and small blood vessels
69. Regulation of VEGF/VPF expression in tumor cells: Consequences for tumor growth and metastasis
70. Vascular endothelial growth factor/vascular permeability factor enhances vascular permeability via nitric oxide and prostacyclin
71. Modulation of eicosanoid metabolism in endothelial cells in a xenograft model. Role of cyclooxygenase-2
72. 2 is a mediator of cyclooxygenase-2-dependent endothelial migration and angiogenesis
73. 1 in osteoblasts
74. Expression and regulation of vascular endothelial growth factor in osteoblasts
75. Induction of vascular endothelial growth factor expression in synovial fibroblasts by prostaglandin E and interleukin-1: A potential mechanism for inflammatory angiogenesis
76. 2 induces vascular endothelial growth factor and basic fibroblast growth factor mRNA expression in cultured rat Muller cells
77. A genetic model for colorectal tumorigenesis
78. Mutant ras oncogenes upregulate VEGF/VPF expression: Implications for induction and inhibition of tumor angiogenesis
79. Impact of oncogenes in tumor angiogenesis: Mutant K-ras up-regulation of vascular endothelial growth factor/vascular permeability factor is necessary, but not sufficient for tumorigenicity of human colorectal carcinoma cells
80. Both v-Ha-ras and v-raf stimulate expression of the vascular endothelial growth factor in NIH 3T3 cells
81. Oncogenic H-ras stimulates tumor angiogenesis by two distinct pathways
82. Up-regulation of vascular endothelial growth factor/vascular permeability factor in mouse skin carcinogenesis correlates with malignant progression state and activated H-ras expression levels
83. Lovastatin and tumor necrosis factor-α exhibit potentiated antitumor effects against Ha-ras-transformed murine tumor via inhibition of tumor-induced angiogenesis
84. The up-regulation of vascular endothelial growth factor in mutated Ha-ras HaCaT cell lines is reduced by a farnesyl transferase inhibitor
85. Normoxic and hypoxic regulation of vascular endothelial growth factor (VEGF) by astrocytoma cells is mediated by Ras
86. Differential expression and mutation of the ras family genes in human breast cancer
87. c-Myc protein expression in untransformed fibroblasts
88. Regulation of c-myc expression by Ras/Raf signalling
89. 2 by oncogenic Ras in human nonsmall cell lung cancer
90. Enhanced angiogenesis and growth of 12-lipoxygenase gene-transfected MCF-7 human breast cancer cells in athymic nude mice
91. Platelet-type 12-lipoxygenase in a human prostate carcinoma stimulates angiogenesis and tumor growth
92. The mitogenic effect of 15- and 12-hydroxyeicosatetraenoic acid on endothelial cells may be mediated via diacylglycerol kinase inhibition
93. 12(S)-HETE is a mitogenic factor for microvascular endothelial cells: Its potential role in angiogenesis
94. Arachidonic acid metabolites in bFGF-, PDGF-, and serum-stimulated vascular cell growth
95. 3 for angiogenesis
96. 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels
97. Basement membrane collagen: Degradation by migrating endothelial cells
98. Basic fibroblast growth factor induces angiogenesis in vitro
99. Transcriptional activation of endothelial cell integrin α(v) by protein kinase C activator 12 (S)-HETE
100. Lipoxygenase metabolites of arachidonic and linoleic acids modulate the adhesion of tumor cells to endothelium via regulation of protein kinase C
101. Tumor cells secrete an angiogenic factor that stimulates basic fibroblast growth factor and urokinase expression in vascular endothelial cells
102. Regulation of matrix metalloproteinase expression in human vein and microvascular endothelial cells
103. Eicosanoids as mediators of linoleic acid-stimulated invasion and type IV collagenase production by a metastatic human breast cancer cell line
104. The influence of angiogenesis research on management of patients with breast cancer
105. Angiogenesis: Mechanistic insights, neovascular diseases, and therapeutic prospects
106. Tumour vasculature - A potent therapeutic target
107. Suramin, an anticancer and antisuppressive agent, inhibits endothelial cell binding of basic fibroblast growth factor, migration, proliferation, and induction of urokinase-type plasminogen activator
108. Flavonoids, dietary-derived inhibitors of cell proliferation and in vitro angiogenesis
109. Antiangiogenic activity of arachidonic acid metabolism inhibitors in angiogenesis model systems involving human microvascular endothelial cells and neovascularization in mice
110. Effects of chronic indomethacin therapy on the development and progression of spontaneous mammary tumors in C3H/HEJ mice
111. The effect of dietary n-3 and n-6 polyunsaturated fatty acids on the expression of cyclooxygenase 1 and 2 and levels of p21(ras) in rat mammary glands
112. Inhibition by dietary menhaden oil of cyclooxygenase-1 and -2 in N-nitrosomethylurea-induced rat mammary tumors
113. Effects of dietary menhaden oil, soy, and a cyclooxygenase inhibitor on human breast cancer cell growth and metastasis in nude mice
114. ω-3 fatty acids as cancer chemopreventive agents
115. Inhibition of cyclooxygenase: A novel approach to cancer prevention