-
1
-
-
0032532270
-
Atypical protein kinase C lambda binds and regulates p70 S6 kinase
-
Akimoto K., Nakaya M., Yamanaka T., Tanaka J., Matsuda S., Weng Q., Avruch P. J., Ohno S. Atypical protein kinase C lambda binds and regulates p70 S6 kinase. Biochem. J. 335:1998;417-424.
-
(1998)
Biochem. J.
, vol.335
, pp. 417-424
-
-
Akimoto, K.1
Nakaya, M.2
Yamanaka, T.3
Tanaka, J.4
Matsuda, S.5
Weng, Q.6
Avruch, P.J.7
Ohno, S.8
-
2
-
-
0030022346
-
EGF or PDGF receptors activate atypical PKClambda through phosphatidylinositol 3-kinase
-
Akimoto K., Takahashi R., Moriya S., Nishioka N., Takayanagi J., Kimura K., Fukui Y., Osada S., Mizuno K., Hirai S., Kazlauskas A., Ohno S. EGF or PDGF receptors activate atypical PKClambda through phosphatidylinositol 3-kinase. EMBO J. 15:1996;788-798.
-
(1996)
EMBO J.
, vol.15
, pp. 788-798
-
-
Akimoto, K.1
Takahashi, R.2
Moriya, S.3
Nishioka, N.4
Takayanagi, J.5
Kimura, K.6
Fukui, Y.7
Osada, S.8
Mizuno, K.9
Hirai, S.10
Kazlauskas, A.11
Ohno, S.12
-
3
-
-
0029804116
-
Mechanism of activation of protein kinase B by insulin and IGF-1
-
Alessi D., Andjelkovic M., Caudwell B., Cron P., Morrice N., Cohen P., Hemmings B. A. Mechanism of activation of protein kinase B by insulin and IGF-1. EMBO J. 23:1996;6541-6551.
-
(1996)
EMBO J.
, vol.23
, pp. 6541-6551
-
-
Alessi, D.1
Andjelkovic, M.2
Caudwell, B.3
Cron, P.4
Morrice, N.5
Cohen, P.6
Hemmings, B.A.7
-
4
-
-
12644301164
-
3-Phosphoinositide-dependent protein kinase-1 (PDK1): Structural and functional homology with the Drosophila DSTPK61 kinase
-
Alessi D. R., Deak M., Casamayor A., Caudwell F. B., Morrice N., Norman D. G., Gaffney P., Reese C. B., MacDougall C. N., Harbison D., Ashworth A., Bownes M. 3-Phosphoinositide-dependent protein kinase-1 (PDK1): Structural and functional homology with the Drosophila DSTPK61 kinase. Curr. Biol. 7:1997;776-789.
-
(1997)
Curr. Biol.
, vol.7
, pp. 776-789
-
-
Alessi, D.R.1
Deak, M.2
Casamayor, A.3
Caudwell, F.B.4
Morrice, N.5
Norman, D.G.6
Gaffney, P.7
Reese, C.B.8
MacDougall, C.N.9
Harbison, D.10
Ashworth, A.11
Bownes, M.12
-
5
-
-
0031127305
-
Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase B alpha
-
Alessi D. R., James S. R., Downes C. P., Holmes A. B., Gaffney P. R., Reese C. B., Cohen P. Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase B alpha. Curr. Biol. 7:1997;261-269.
-
(1997)
Curr. Biol.
, vol.7
, pp. 261-269
-
-
Alessi, D.R.1
James, S.R.2
Downes, C.P.3
Holmes, A.B.4
Gaffney, P.R.5
Reese, C.B.6
Cohen, P.7
-
6
-
-
0032518467
-
3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro
-
Alessi D. R., Kozlowski M. T., Weng Q. P., Morrice N., Avruch J. 3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro. Curr. Biol. 8:1998;69-81.
-
(1998)
Curr. Biol.
, vol.8
, pp. 69-81
-
-
Alessi, D.R.1
Kozlowski, M.T.2
Weng, Q.P.3
Morrice, N.4
Avruch, J.5
-
8
-
-
0033043389
-
Domain swapping used to investigate the mechanism of protein kinase B regulation by 3-phosphoinositide-dependent protein kinase 1 and Ser473 kinase
-
Andjelkovic M., Maira S. M., Cron P., Parker P. J., Hemmings B. A. Domain swapping used to investigate the mechanism of protein kinase B regulation by 3-phosphoinositide-dependent protein kinase 1 and Ser473 kinase. Mol. Cell. Biol. 19:1999;5061-5072.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 5061-5072
-
-
Andjelkovic, M.1
Maira, S.M.2
Cron, P.3
Parker, P.J.4
Hemmings, B.A.5
-
9
-
-
0023849673
-
Protein phosphatase 2A inactivates the mitogen-stimulated S6 kinase from Swiss mouse 3T3 cells
-
Ballou L. M., Jeno P., Thomas G. Protein phosphatase 2A inactivates the mitogen-stimulated S6 kinase from Swiss mouse 3T3 cells. J. Biol. Chem. 263:1988;1188-1194.
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 1188-1194
-
-
Ballou, L.M.1
Jeno, P.2
Thomas, G.3
-
10
-
-
0025016341
-
Molecular structure of a major insulin/mitogen-activated 70 kDa S6 protein kinase
-
Banerjee P., Ahamad M. F., Grove J. R., Kozlosky C., Price D. J., Avruch J. Molecular structure of a major insulin/mitogen-activated 70 kDa S6 protein kinase. Proc. Natl. Acad. Sci. USA. 87:1990;8550-8554.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 8550-8554
-
-
Banerjee, P.1
Ahamad, M.F.2
Grove, J.R.3
Kozlosky, C.4
Price, D.J.5
Avruch, J.6
-
11
-
-
0029856725
-
CAMP counter-regulates insulin-mediated protein phosphatase-2A inactivation in rat skeletal muscle cells
-
Begum N., Ragolia L. cAMP counter-regulates insulin-mediated protein phosphatase-2A inactivation in rat skeletal muscle cells. J. Biol. Chem. 271:1996;31166-31171.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 31166-31171
-
-
Begum, N.1
Ragolia, L.2
-
12
-
-
0028899789
-
Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes
-
Blommaart E. F., Luiken J. J., Blommaart P. J., van Woerkom G. M., Meijer A. J. Phosphorylation of ribosomal protein S6 is inhibitory for autophagy in isolated rat hepatocytes. J. Biol. Chem. 270:1995;2320-2326.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 2320-2326
-
-
Blommaart, E.F.1
Luiken, J.J.2
Blommaart, P.J.3
Van Woerkom, G.M.4
Meijer, A.J.5
-
13
-
-
0033000334
-
P70(s6k) integrates phosphatidylinositol 3-kinase and rapamycin-regulated signals for E2F regulation in T lymphocytes
-
Brennan P., Babbage J. W., Thomas G., Cantrell D. p70(s6k) integrates phosphatidylinositol 3-kinase and rapamycin-regulated signals for E2F regulation in T lymphocytes. Mol. Cell. Biol. 19:1999;4729-4738.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 4729-4738
-
-
Brennan, P.1
Babbage, J.W.2
Thomas, G.3
Cantrell, D.4
-
14
-
-
0028360374
-
A mammalian protein targeted by G1-arresting rapamycin-receptor complex
-
Brown E. J., Albers M. A., Shin T. B., Ichikawa K., Keith C. T., Lane W. S., Schreiber S. L. A mammalian protein targeted by G1-arresting rapamycin-receptor complex. Nature. 369:1994;756-758.
-
(1994)
Nature
, vol.369
, pp. 756-758
-
-
Brown, E.J.1
Albers, M.A.2
Shin, T.B.3
Ichikawa, K.4
Keith, C.T.5
Lane, W.S.6
Schreiber, S.L.7
-
15
-
-
0029160069
-
Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
-
Burgering B. M. T., Coffer P. J. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature. 376:1995;599-602.
-
(1995)
Nature
, vol.376
, pp. 599-602
-
-
Burgering, B.M.T.1
Coffer, P.J.2
-
16
-
-
0032539664
-
RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1
-
Burnett P. E., Barrow R. K., Cohen N. A., Snyder S. H., Sabatini D. M. RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1. Proc. Natl. Acad. Sci. USA. 95:1998;1432-1437.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 1432-1437
-
-
Burnett, P.E.1
Barrow, R.K.2
Cohen, N.A.3
Snyder, S.H.4
Sabatini, D.M.5
-
17
-
-
0032493285
-
Neurabin is a synaptic protein linking p70 S6 kinase and the neuronal cytoskeleton
-
Burnett P. E., Blackshaw S., Lai M. M., Qureshi I. A., Burnett A. F., Sabatini D. M., Snyder S. H. Neurabin is a synaptic protein linking p70 S6 kinase and the neuronal cytoskeleton. Proc. Natl. Acad. Sci. USA. 95:1998;8351-8356.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 8351-8356
-
-
Burnett, P.E.1
Blackshaw, S.2
Lai, M.M.3
Qureshi, I.A.4
Burnett, A.F.5
Sabatini, D.M.6
Snyder, S.H.7
-
18
-
-
0026666050
-
Interleukin 2 stimulation of p70 S6 kinase activity is inhibited by the immunosuppressant rapamycin
-
Calvo V., Crews C. M., Vik T. A., Bierer B. E. Interleukin 2 stimulation of p70 S6 kinase activity is inhibited by the immunosuppressant rapamycin. Proc. Natl. Acad. Sci. USA. 89:1992;7571-7575.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 7571-7575
-
-
Calvo, V.1
Crews, C.M.2
Vik, T.A.3
Bierer, B.E.4
-
19
-
-
0028308412
-
Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation
-
Cheatham B., Vlahos C. J., Cheatham L., Wang L., Blenis J., Kahn C. R. Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation. Mol. Cell. Biol. 14:1994;4902-4911.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 4902-4911
-
-
Cheatham, B.1
Vlahos, C.J.2
Cheatham, L.3
Wang, L.4
Blenis, J.5
Kahn, C.R.6
-
22
-
-
0032563936
-
Regulation of protein kinase C zeta by PI 3-kinase and PDK-1
-
Chou M. M., Hou W., Johnson J., Graham L. K., Lee M. H., Chen C. S., Newton A. C., Schaffhausen B. S., Toker A. Regulation of protein kinase C zeta by PI 3-kinase and PDK-1. Curr. Biol. 8:1998;1069-1077.
-
(1998)
Curr. Biol.
, vol.8
, pp. 1069-1077
-
-
Chou, M.M.1
Hou, W.2
Johnson, J.3
Graham, L.K.4
Lee, M.H.5
Chen, C.S.6
Newton, A.C.7
Schaffhausen, B.S.8
Toker, A.9
-
24
-
-
0026659046
-
Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kD S6 protein kinases
-
Chung J., Kuo C. J., Crabtree G. R., Blenis J. Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kD S6 protein kinases. Cell. 69:1992;1227-1236.
-
(1992)
Cell
, vol.69
, pp. 1227-1236
-
-
Chung, J.1
Kuo, C.J.2
Crabtree, G.R.3
Blenis, J.4
-
26
-
-
0033593316
-
Size control in animal development
-
Conlon I., Raff M. Size control in animal development. Cell. 96:1999;235-244.
-
(1999)
Cell
, vol.96
, pp. 235-244
-
-
Conlon, I.1
Raff, M.2
-
28
-
-
0033084143
-
Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1
-
Currie R. A., Walker K. S., Gray A., Deak M., Casamayor A., Downes C. P., Cohen P., Alessi D. R., Lucocq J. Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1. Biochem. J. 337:1999;575-583.
-
(1999)
Biochem. J.
, vol.337
, pp. 575-583
-
-
Currie, R.A.1
Walker, K.S.2
Gray, A.3
Deak, M.4
Casamayor, A.5
Downes, C.P.6
Cohen, P.7
Alessi, D.R.8
Lucocq, J.9
-
29
-
-
0032999830
-
Target of rapamycin (TOR): Balancing the opposing forces of protein synthesis and degradation
-
Dennis P. B., Fumagalli S., Thomas G. Target of rapamycin (TOR): Balancing the opposing forces of protein synthesis and degradation. Curr. Opin. Genet. Dev. 9:1999;49-54.
-
(1999)
Curr. Opin. Genet. Dev.
, vol.9
, pp. 49-54
-
-
Dennis, P.B.1
Fumagalli, S.2
Thomas, G.3
-
32
-
-
0029808294
-
Nutrients, via the Tor proteins, stimulate the association of Tap42 with type 2A phosphatases
-
Di Como C. J., Arndt K. T. Nutrients, via the Tor proteins, stimulate the association of Tap42 with type 2A phosphatases. Genes Dev. 10:1996;1904-1916.
-
(1996)
Genes Dev.
, vol.10
, pp. 1904-1916
-
-
Di Como, C.J.1
Arndt, K.T.2
-
33
-
-
0032973572
-
Protein kinase B localization and activation differentially affect S6 kinase 1 activity and eukaryotic translation initiation factor 4E-binding protein 1 phosphorylation
-
Dufner A., Andjelkovic M., Burgering B. M. T., Hemmings B. A., Thomas G. Protein kinase B localization and activation differentially affect S6 kinase 1 activity and eukaryotic translation initiation factor 4E-binding protein 1 phosphorylation. Mol. Cell. Biol. 19:1999;4525-4534.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 4525-4534
-
-
Dufner, A.1
Andjelkovic, M.2
Burgering, B.M.T.3
Hemmings, B.A.4
Thomas, G.5
-
34
-
-
0028222874
-
Autophagy and related mechanisms of lysosome-mediated protein degradation
-
Dunn W. A. J. Autophagy and related mechanisms of lysosome-mediated protein degradation. Trends Cell Biol. 4:1994;139-143.
-
(1994)
Trends Cell Biol.
, vol.4
, pp. 139-143
-
-
Dunn, W.A.J.1
-
35
-
-
0030029152
-
Cell cycle regulation of p70 S6 kinase and p42/p44 mitogen-activated protein kinases in Swiss mouse 3T3 fibroblasts
-
Edelmann H. M. L., Kühne C., Petritsch C., Ballou L. M. Cell cycle regulation of p70 S6 kinase and p42/p44 mitogen-activated protein kinases in Swiss mouse 3T3 fibroblasts. J. Biol. Chem. 271:1996;963-971.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 963-971
-
-
Edelmann, H.M.L.1
Kühne, C.2
Petritsch, C.3
Ballou, L.M.4
-
38
-
-
0026688510
-
Substrate recognition determinants of the mitogen-activated 70K S6 kinase from rat liver
-
Flotow H., Thomas G. Substrate recognition determinants of the mitogen-activated 70K S6 kinase from rat liver. J. Biol. Chem. 267:1992;3074-3078.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 3074-3078
-
-
Flotow, H.1
Thomas, G.2
-
39
-
-
0025215702
-
Hormonally inducible phosphorylation of a nuclear pool of ribosomal protein S6
-
Franco R., Rosenfeld M. G. Hormonally inducible phosphorylation of a nuclear pool of ribosomal protein S6. J. Biol. Chem. 265:1990;4321-4325.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 4321-4325
-
-
Franco, R.1
Rosenfeld, M.G.2
-
40
-
-
0032143922
-
The broad specificity of dominant inhibitory protein kinase C mutants infers a common step in phosphorylation
-
Garcia-Paramio P., Cabrerizo Y., Bornancin F., Parker P. J. The broad specificity of dominant inhibitory protein kinase C mutants infers a common step in phosphorylation. Biochem. J. 333:1998;631-636.
-
(1998)
Biochem. J.
, vol.333
, pp. 631-636
-
-
Garcia-Paramio, P.1
Cabrerizo, Y.2
Bornancin, F.3
Parker, P.J.4
-
41
-
-
0025986847
-
Cloning and expression of two human p70 S6 kinase polypeptides differing only at their amino termini
-
Grove J. R., Banerjee P., Balasubramanyam A., Coffer P. J., Price D. J., Avruch J., Woodgett J. R. Cloning and expression of two human p70 S6 kinase polypeptides differing only at their amino termini. Mol. Cell. Biol. 11:1991;5541-5550.
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 5541-5550
-
-
Grove, J.R.1
Banerjee, P.2
Balasubramanyam, A.3
Coffer, P.J.4
Price, D.J.5
Avruch, J.6
Woodgett, J.R.7
-
42
-
-
0031782480
-
Constitutive activation of protein kinase B alpha by membrane targeting promotes glucose and system A amino acid transport, protein synthesis, and inactivation of glycogen synthase kinase 3 in L6 muscle cells
-
Hajduch E., Alessi D. R., Hemmings B. A., Hundal H. S. Constitutive activation of protein kinase B alpha by membrane targeting promotes glucose and system A amino acid transport, protein synthesis, and inactivation of glycogen synthase kinase 3 in L6 muscle cells. Diabetes. 47:1998;1006-1013.
-
(1998)
Diabetes
, vol.47
, pp. 1006-1013
-
-
Hajduch, E.1
Alessi, D.R.2
Hemmings, B.A.3
Hundal, H.S.4
-
44
-
-
0032486268
-
Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism
-
Hara K., Yonezawa K., Weng Q. P., Kozlowski M. J., Belham C., Avruch J. Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism. J. Biol. Chem. 273:1998;14484-14494.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 14484-14494
-
-
Hara, K.1
Yonezawa, K.2
Weng, Q.P.3
Kozlowski, M.J.4
Belham, C.5
Avruch, J.6
-
45
-
-
0033534686
-
Amino acid-dependent control of p70(s6k). Involvement of tRNA aminoacylation in the regulation
-
Iiboshi Y., Papst P. J., Kawasome H., Hosoi H., Abraham R. T., Houghton P. J., Terada N. Amino acid-dependent control of p70(s6k). Involvement of tRNA aminoacylation in the regulation. J. Biol. Chem. 274:1999;1092-1099.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 1092-1099
-
-
Iiboshi, Y.1
Papst, P.J.2
Kawasome, H.3
Hosoi, H.4
Abraham, R.T.5
Houghton, P.J.6
Terada, N.7
-
47
-
-
0004041025
-
-
J. W. B. Hershey, M. B. Mathews, & N. Sonenberg. Cold Spring Harbor: Cold Spring Harbor Laboratory Press
-
Jefferies H. B. J., Thomas G. Hershey J. W. B., Mathews M. B., Sonenberg N. Translational Control. 1996;389-409 Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
-
(1996)
Translational Control
, pp. 389-409
-
-
Jefferies, H.B.J.1
Thomas, G.2
-
49
-
-
0033577745
-
Tor proteins and protein phosphatase 2A reciprocally regulate Tap42 in controlling cell growth in yeast
-
Jiang Y., Broach J. R. Tor proteins and protein phosphatase 2A reciprocally regulate Tap42 in controlling cell growth in yeast. EMBO J. 18:1999;2782-2792.
-
(1999)
EMBO J.
, vol.18
, pp. 2782-2792
-
-
Jiang, Y.1
Broach, J.R.2
-
50
-
-
0029908016
-
Expression of a constitutively active Akt ser/thr kinase in 3T3 adipocytes stimulates glucose uptake and glucose transporter 4 translocation
-
Kohn A. D., Summers S. A., Birnbaum M. J., Roth R. A. Expression of a constitutively active Akt ser/thr kinase in 3T3 adipocytes stimulates glucose uptake and glucose transporter 4 translocation. J. Biol. Chem. 271:1996;31372-31378.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 31372-31378
-
-
Kohn, A.D.1
Summers, S.A.2
Birnbaum, M.J.3
Roth, R.A.4
-
51
-
-
0031724590
-
Requirement of atypical protein kinase c lambda for insulin stimulation of glucose uptake but not for Akt activation in 3T3-L1 adipocytes
-
Kotani K., Ogawa W., Matsumoto M., Kitamura T., Sakaue H., Hino Y., Miyake K., Sano W., Akimoto K., Ohno S., Kasuga M. Requirement of atypical protein kinase c lambda for insulin stimulation of glucose uptake but not for Akt activation in 3T3-L1 adipocytes. Mol. Cell. Biol. 18:1998;6971-6982.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 6971-6982
-
-
Kotani, K.1
Ogawa, W.2
Matsumoto, M.3
Kitamura, T.4
Sakaue, H.5
Hino, Y.6
Miyake, K.7
Sano, W.8
Akimoto, K.9
Ohno, S.10
Kasuga, M.11
-
52
-
-
0025029035
-
Cloning of the mitogen-activated S6 kinase from rat liver reveals an enzyme of the second messenger subfamily
-
Kozma S. C., Ferrari S., Bassand P., Siegmann M., Totty N., Thomas G. Cloning of the mitogen-activated S6 kinase from rat liver reveals an enzyme of the second messenger subfamily. Proc. Natl. Acad. Sci. USA. 87:1990;7365-7369.
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 7365-7369
-
-
Kozma, S.C.1
Ferrari, S.2
Bassand, P.3
Siegmann, M.4
Totty, N.5
Thomas, G.6
-
54
-
-
0026721092
-
Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase
-
Kuo C. J., Chung J., Fiorentino D. F., Flanagan W. M., Blenis J., Crabtree G. R. Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase. Nature. 358:1992;70-73.
-
(1992)
Nature
, vol.358
, pp. 70-73
-
-
Kuo, C.J.1
Chung, J.2
Fiorentino, D.F.3
Flanagan, W.M.4
Blenis, J.5
Crabtree, G.R.6
-
56
-
-
0032566691
-
Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1
-
Le Good J. A., Ziegler W. H., Parekh D. B., Alessi D. R., Cohen P., Parker P. J. Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1. Science. 281:1998;2042-2045.
-
(1998)
Science
, vol.281
, pp. 2042-2045
-
-
Le Good, J.A.1
Ziegler, W.H.2
Parekh, D.B.3
Alessi, D.R.4
Cohen, P.5
Parker, P.J.6
-
57
-
-
0032061042
-
Exocytosis of insulin promotes insulin gene transcription via the insulin receptor/PI-3 kinase/p70 s6 kinase and CaM kinase pathways
-
Leibiger I. B., Leibiger B., Moede T., Berggren P. O. Exocytosis of insulin promotes insulin gene transcription via the insulin receptor/PI-3 kinase/p70 s6 kinase and CaM kinase pathways. Mol. Cell. 1:1998;933-938.
-
(1998)
Mol. Cell
, vol.1
, pp. 933-938
-
-
Leibiger, I.B.1
Leibiger, B.2
Moede, T.3
Berggren, P.O.4
-
58
-
-
0004041025
-
-
J. W. B. Hershey, M. B. Mathews, & N. Sonenberg. Cold Spring Harbor: Cold Spring Harbor Laboratory Press
-
Meyuhas O., Avni D., Shama S. Hershey J. W. B., Mathews M. B., Sonenberg N. Translational Control. 1996;Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
-
(1996)
Translational Control
-
-
Meyuhas, O.1
Avni, D.2
Shama, S.3
-
59
-
-
0028168073
-
ras
-
ras. Nature. 371:1994;426-429.
-
(1994)
Nature
, vol.371
, pp. 426-429
-
-
Ming, X.F.1
Burgering, B.M.T.2
Wennström, S.3
Claesson-Welsh, L.4
Heldin, C.H.5
Bos, J.L.6
Kozma, S.C.7
Thomas, G.8
-
60
-
-
0032843917
-
Drosophila S6 kinase: A regulator of cell size
-
Montagne J., Stewart M. J., Stocker H., Hafen E., Kozma S. C., Thomas G. Drosophila S6 kinase: A regulator of cell size. Science. 285:1999;2126-2129.
-
(1999)
Science
, vol.285
, pp. 2126-2129
-
-
Montagne, J.1
Stewart, M.J.2
Stocker, H.3
Hafen, E.4
Kozma, S.C.5
Thomas, G.6
-
61
-
-
0030848939
-
s6k
-
s6k. Mol. Cell. Biol. 17:1997;5648-5655.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 5648-5655
-
-
Moser, B.A.1
Dennis, P.B.2
Pullen, N.3
Pearson, R.B.4
Williamson, N.A.5
Wettenhall, E.H.6
Kozma, S.C.7
Thomas, G.8
-
62
-
-
0026757270
-
An array of insulin-activated, proline-directed serine/threonine protein kinases phosphorylate the p70 S6 kinase
-
Mukhopadhayay N. K., Price D. J., Kyriakis J. M., Pelech S. L., Sanghera J., Avruch J. An array of insulin-activated, proline-directed serine/threonine protein kinases phosphorylate the p70 S6 kinase. J. Biol. Chem. 267:1992;3325-3335.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 3325-3335
-
-
Mukhopadhayay, N.K.1
Price, D.J.2
Kyriakis, J.M.3
Pelech, S.L.4
Sanghera, J.5
Avruch, J.6
-
63
-
-
0030984108
-
B cell receptor-associated protein alpha4 displays rapamycin-sensitive binding directly to the catalytic subunit of protein phosphatase 2A
-
Murata K., Wu J., Brautigan D. L. B cell receptor-associated protein alpha4 displays rapamycin-sensitive binding directly to the catalytic subunit of protein phosphatase 2A. Proc. Natl. Acad. Sci. USA. 94:1997;10624-10629.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 10624-10629
-
-
Murata, K.1
Wu, J.2
Brautigan, D.L.3
-
64
-
-
0027535742
-
Activation of the zeta isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate
-
Nakanishi H., Brewer K. A., Exton J. H. Activation of the zeta isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate. J. Biol. Chem. 268:1993;13-16.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 13-16
-
-
Nakanishi, H.1
Brewer, K.A.2
Exton, J.H.3
-
65
-
-
0030682482
-
Neurabin: A novel neural tissue-specific actin filament-binding protein involved in neurite formation
-
Nakanishi H., Obaishi H., Satoh A., Wada M., Mandai K., Satoh K., Nishioka H., Matsuura Y., Mizoguchi A., Takai Y. Neurabin: A novel neural tissue-specific actin filament-binding protein involved in neurite formation. J. Cell Biol. 139:1997;951-961.
-
(1997)
J. Cell Biol.
, vol.139
, pp. 951-961
-
-
Nakanishi, H.1
Obaishi, H.2
Satoh, A.3
Wada, M.4
Mandai, K.5
Satoh, K.6
Nishioka, H.7
Matsuura, Y.8
Mizoguchi, A.9
Takai, Y.10
-
66
-
-
0032552873
-
Regulation of protein phosphatase 2A catalytic activity by alpha4 and its yeast homolog Tap42
-
Nanahoshi M., Nishiuma T., Tsujishita Y., Hara K., Inui S., Sakaguchi N., Yonezawa K. Regulation of protein phosphatase 2A catalytic activity by alpha4 and its yeast homolog Tap42. Biochem. Biophys. Res. Commun. 251:1998;520-526.
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.251
, pp. 520-526
-
-
Nanahoshi, M.1
Nishiuma, T.2
Tsujishita, Y.3
Hara, K.4
Inui, S.5
Sakaguchi, N.6
Yonezawa, K.7
-
67
-
-
0025291205
-
Translational dynamics. Interactions between the translational factors, tRNA and ribosomes during eukaryotic protein synthesis
-
Nygard O., Nilsson L. Translational dynamics. Interactions between the translational factors, tRNA and ribosomes during eukaryotic protein synthesis. Eur. J. Biochem. 191:1990;1-17.
-
(1990)
Eur. J. Biochem.
, vol.191
, pp. 1-17
-
-
Nygard, O.1
Nilsson, L.2
-
68
-
-
0023761302
-
Differential regulation of S6 phosphorylation by insulin and epidermal growth factor in Swiss mouse 3T3 cells: Insulin activation of type 1 phosphatase
-
Olivier A. R., Ballou L. M., Thomas G. Differential regulation of S6 phosphorylation by insulin and epidermal growth factor in Swiss mouse 3T3 cells: Insulin activation of type 1 phosphatase. Proc. Natl. Acad. Sci. USA. 85:1988;4720-4724.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 4720-4724
-
-
Olivier, A.R.1
Ballou, L.M.2
Thomas, G.3
-
69
-
-
0032510976
-
Cdc2-cyclin B phosphorylates p70 S6 kinase on Ser411 at mitosis
-
Papst P. J., Sugiyama H., Nagasawa M., Lucas J. J., Maller J. L., Terada N. Cdc2-cyclin B phosphorylates p70 S6 kinase on Ser411 at mitosis. J. Biol. Chem. 273:1998;15077-15084.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 15077-15084
-
-
Papst, P.J.1
Sugiyama, H.2
Nagasawa, M.3
Lucas, J.J.4
Maller, J.L.5
Terada, N.6
-
71
-
-
0031588899
-
Cellular nucleic acid binding protein binds a conserved region of the 5′ UTR of Xenopus laevis ribosomal protein mRNAs
-
Pellizzoni L., Lotti F., Maras B., Pierandrei-Amaldi P. Cellular nucleic acid binding protein binds a conserved region of the 5′ UTR of Xenopus laevis ribosomal protein mRNAs. J. Mol. Biol. 267:1997;264-275.
-
(1997)
J. Mol. Biol.
, vol.267
, pp. 264-275
-
-
Pellizzoni, L.1
Lotti, F.2
Maras, B.3
Pierandrei-Amaldi, P.4
-
72
-
-
0032575761
-
Involvement of the Xenopus laevis Ro60 autoantigen in the alternative interaction of La and CNBP proteins with the 5′UTR of L4 ribosomal protein mRNA
-
Pellizzoni L., Lotti F., Rutjes S. A., Pierandrei-Amaldi P. Involvement of the Xenopus laevis Ro60 autoantigen in the alternative interaction of La and CNBP proteins with the 5′UTR of L4 ribosomal protein mRNA. J. Mol. Biol. 281:1998;593-608.
-
(1998)
J. Mol. Biol.
, vol.281
, pp. 593-608
-
-
Pellizzoni, L.1
Lotti, F.2
Rutjes, S.A.3
Pierandrei-Amaldi, P.4
-
73
-
-
0033551234
-
Protein phosphatase 2A interacts with the 70-kDa S6 kinase and is activated by inhibition of FKBP12-rapamycin-associated protein
-
Peterson R. T., Desai B. N., Hardwick J. S., Schreiber S. L. Protein phosphatase 2A interacts with the 70-kDa S6 kinase and is activated by inhibition of FKBP12-rapamycin-associated protein. Proc. Natl. Acad. Sci. USA. 96:1999;4438-4442.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 4438-4442
-
-
Peterson, R.T.1
Desai, B.N.2
Hardwick, J.S.3
Schreiber, S.L.4
-
74
-
-
0032568269
-
Translation control: Connecting mitogens and the ribosome
-
Peterson R. T., Schreiber S. L. Translation control: Connecting mitogens and the ribosome. Curr. Biol. 8:1998;R248-R250.
-
(1998)
Curr. Biol.
, vol.8
-
-
Peterson, R.T.1
Schreiber, S.L.2
-
75
-
-
0026759874
-
Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase
-
Price D. J., Grove J. R., Calvo V., Avruch J., Bierer B. E. Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase. Science. 257:1992;973-977.
-
(1992)
Science
, vol.257
, pp. 973-977
-
-
Price, D.J.1
Grove, J.R.2
Calvo, V.3
Avruch, J.4
Bierer, B.E.5
-
76
-
-
0025948372
-
Insulin-activated kinases phosphorylate a pseudo-substrate inhibitor of the p70 S6 kinase
-
Price D. J., Mukhopadhyay N. K., Avruch J. Insulin-activated kinases phosphorylate a pseudo-substrate inhibitor of the p70 S6 kinase. J. Biol. Chem. 266:1991;16281-16284.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 16281-16284
-
-
Price, D.J.1
Mukhopadhyay, N.K.2
Avruch, J.3
-
80
-
-
0026504296
-
A single gene encodes two isoforms of the p70 S6 kinase: Activation upon mitogenic stimulation
-
Reinhard C., Thomas G., Kozma S. C. A single gene encodes two isoforms of the p70 S6 kinase: Activation upon mitogenic stimulation. Proc. Natl. Acad. Sci. USA. 89:1992;4052-4056.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 4052-4056
-
-
Reinhard, C.1
Thomas, G.2
Kozma, S.C.3
-
81
-
-
0032932198
-
P70 S6 kinase is regulated by protein kinase C zeta and participates in a phosphoinositide 3-kinase-regulated signaling complex
-
Romanelli A., Martin K. A., Toker A., Blenis J. p70 S6 kinase is regulated by protein kinase C zeta and participates in a phosphoinositide 3-kinase-regulated signaling complex. Mol. Cell. Biol. 19:1999;2921-2928.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 2921-2928
-
-
Romanelli, A.1
Martin, K.A.2
Toker, A.3
Blenis, J.4
-
82
-
-
0028239893
-
RAFT1: A mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs
-
Sabatini D. M., Erdjument-Bromage H., Lui M., Tempst P., Snyder S. H. RAFT1: A mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs. Cell. 78:1994;35-43.
-
(1994)
Cell
, vol.78
, pp. 35-43
-
-
Sabatini, D.M.1
Erdjument-Bromage, H.2
Lui, M.3
Tempst, P.4
Snyder, S.H.5
-
83
-
-
0033534734
-
Regulation of translational effectors by amino acid and mammalian target of rapamycin signaling pathways. Possible involvement of autophagy in cultured hepatoma cells
-
Shigemitsu K., Tsujishita Y., Hara K., Nanahoshi M., Avruch J., Yonezawa K. Regulation of translational effectors by amino acid and mammalian target of rapamycin signaling pathways. Possible involvement of autophagy in cultured hepatoma cells. J. Biol. Chem. 274:1999;1058-1065.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 1058-1065
-
-
Shigemitsu, K.1
Tsujishita, Y.2
Hara, K.3
Nanahoshi, M.4
Avruch, J.5
Yonezawa, K.6
-
85
-
-
0004041025
-
-
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
-
Sonenberg N. Translational Control. 1996;Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
-
(1996)
Translational Control
-
-
Sonenberg, N.1
-
86
-
-
0030810216
-
Protein kinase C-zeta as a downstream effector of phosphatidylinositol 3-kinase during insulin stimulation in rat adipocytes. Potential role in glucose transport
-
Standaert M. L., Galloway L., Karnam P., Bandyopadhyay G., Moscat J., Farese R. V. Protein kinase C-zeta as a downstream effector of phosphatidylinositol 3-kinase during insulin stimulation in rat adipocytes. Potential role in glucose transport. J. Biol. Chem. 272:1997;30075-30082.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 30075-30082
-
-
Standaert, M.L.1
Galloway, L.2
Karnam, P.3
Bandyopadhyay, G.4
Moscat, J.5
Farese, R.V.6
-
87
-
-
0032578999
-
Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B
-
Stephens L., Anderson K., Stokoe D., Erdjument-Bromage H., Painter G. F., Holmes A. B., Gaffney P. R., Reese C. B., McCormick F., Tempst P., Coadwell J., Hawkins P. T. Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B. Science. 279:1998;710-714.
-
(1998)
Science
, vol.279
, pp. 710-714
-
-
Stephens, L.1
Anderson, K.2
Stokoe, D.3
Erdjument-Bromage, H.4
Painter, G.F.5
Holmes, A.B.6
Gaffney, P.R.7
Reese, C.B.8
McCormick, F.9
Tempst, P.10
Coadwell, J.11
Hawkins, P.T.12
-
88
-
-
0028533984
-
Mitogenesis and protein synthesis: A role for ribosomal protein S6 phosphorylation
-
Stewart M. J., Thomas G. Mitogenesis and protein synthesis: A role for ribosomal protein S6 phosphorylation. BioEssays. 16:1994;1-7.
-
(1994)
BioEssays
, vol.16
, pp. 1-7
-
-
Stewart, M.J.1
Thomas, G.2
-
89
-
-
0030799706
-
Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B
-
Stokoe D., Stephens L. R., Copeland T., Gaffney P. R. J., Reese C. B., Painter G. F., Holmes A. B., McCormick F., Hawkins P. T. Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B. Science. 277:1997;567-570.
-
(1997)
Science
, vol.277
, pp. 567-570
-
-
Stokoe, D.1
Stephens, L.R.2
Copeland, T.3
Gaffney, P.R.J.4
Reese, C.B.5
Painter, G.F.6
Holmes, A.B.7
McCormick, F.8
Hawkins, P.T.9
-
90
-
-
0032563947
-
Size control: Cell proliferation does not equal growth
-
Su T. T., O'Farrell P. H. Size control: Cell proliferation does not equal growth. Curr. Biol. 8:1998;R687-R689.
-
(1998)
Curr. Biol.
, vol.8
-
-
Su, T.T.1
O'Farrell, P.H.2
-
91
-
-
0030707562
-
TOR signaling and control of cell growth
-
Thomas G., Hall M. N. TOR signaling and control of cell growth. Curr. Opin. Cell Biol. 9:1997;782-787.
-
(1997)
Curr. Opin. Cell Biol.
, vol.9
, pp. 782-787
-
-
Thomas, G.1
Hall, M.N.2
-
93
-
-
0032528917
-
Amino acid availability regulates p70 S6 kinase and multiple translation factors
-
Wang X., Campbell L. E., Miller C. M., Proud C. G. Amino acid availability regulates p70 S6 kinase and multiple translation factors. Biochem. J. 334:1998;261-267.
-
(1998)
Biochem. J.
, vol.334
, pp. 261-267
-
-
Wang, X.1
Campbell, L.E.2
Miller, C.M.3
Proud, C.G.4
-
94
-
-
0028939115
-
Multiple independent inputs are required for activation of the p70 S6 kinase
-
Weng Q.-P., Andrabi K., Kozlowski M. T., Grove J. R., Avruch J. Multiple independent inputs are required for activation of the p70 S6 kinase. Mol. Cell. Biol. 15:1995;2333-2340.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 2333-2340
-
-
Weng, Q.-P.1
Andrabi, K.2
Kozlowski, M.T.3
Grove, J.R.4
Avruch, J.5
-
95
-
-
0032568921
-
Regulation of the p70 S6 kinase by phosphorylation in vivo. Analysis using site-specific anti-phosphopeptide antibodies
-
Weng Q. P., Kozlowski M., Belham C., Zhang A., Comb M. J., Avruch J. Regulation of the p70 S6 kinase by phosphorylation in vivo. Analysis using site-specific anti-phosphopeptide antibodies. J. Biol. Chem. 273:1998;16621-16629.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 16621-16629
-
-
Weng, Q.P.1
Kozlowski, M.2
Belham, C.3
Zhang, A.4
Comb, M.J.5
Avruch, J.6
-
96
-
-
0033534615
-
Identification of kinase-phosphatase signaling modules composed of p70 S6 kinase-protein phosphatase 2A (PP2A) and p21-activated kinase-PP2A
-
Westphal R. S., Coffee R. L. Jr., Marotta A., Pelech S. L., Wadzinski B. E. Identification of kinase-phosphatase signaling modules composed of p70 S6 kinase-protein phosphatase 2A (PP2A) and p21-activated kinase-PP2A. J. Biol. Chem. 274:1999;687-692.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 687-692
-
-
Westphal, R.S.1
Coffee R.L., Jr.2
Marotta, A.3
Pelech, S.L.4
Wadzinski, B.E.5
-
97
-
-
0033587133
-
Rapamycin-sensitive phosphorylation of PKC on a carboxy-terminal site by an atypical PKC complex
-
Ziegler W. H., Parekh D. B., Le Good J. A., Whelan R. D., Kelly J. J., Frech M., Hemmings B. A., Parker P. J. Rapamycin-sensitive phosphorylation of PKC on a carboxy-terminal site by an atypical PKC complex. Curr. Biol. 9:1999;522-529.
-
(1999)
Curr. Biol.
, vol.9
, pp. 522-529
-
-
Ziegler, W.H.1
Parekh, D.B.2
Le Good, J.A.3
Whelan, R.D.4
Kelly, J.J.5
Frech, M.6
Hemmings, B.A.7
Parker, P.J.8
|