Tuberin, the tuberous sclerosis complex 2 tumor suppressor gene product, regulates Rho activation, cell adhesion and migration

Oncogene

Volumn 21, Issue 55, 2002, Pages 8470-8476

  Astrinidis, Aristotelis ^a   Cash, Timothy P ^a   Hunter, Deborah S ^b   Walker, Cheryl L ^b   Chernoff, Jonathan ^a   Henske, Elizabeth P ^a  

^a FOX CHASE CANCER CENTER   (United States)

^b UNIVERSITY OF TEXAS   (United States)

Author keywords

Cell attachment; Cell migration; RhoA; TSC2; Tuberin; Tuberous sclerosis complex

Indexed keywords

FOCAL ADHESION KINASE; PROTEIN CDC42; RAC1 PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; TUBERIN; TUMOR SUPPRESSOR PROTEIN;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELL MIGRATION; CHEMOTAXIS; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; TUBEROUS SCLEROSIS; TUMOR SUPPRESSOR GENE;

ANIMALS; CELL ADHESION; CELL LINE; CELL MOVEMENT; DOGS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, TUMOR SUPPRESSOR; HUMANS; PROTEINS; RATS; REPRESSOR PROTEINS; RHO GTP-BINDING PROTEINS; TRANSFECTION; TUBEROUS SCLEROSIS; TUMOR SUPPRESSOR PROTEINS;

ANIMALIA;

EID: 0037028305     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1205962     Document Type: Article

References (44)

1. Agochiya M, Brunton VG, Owens DW, Parkinson EK, Paraskeva C, Keith WN and Frame MC. (1999). Oncogene, 18, 5646-5653.
2. Benvenuto G, Li S, Brown SJ, Braverman R, Vass WC, Cheadle JP, Halley DJ, Sampson JR, Wienecke R and DeClue JE. (2000). Oncogene, 19, 6306-6316.
3. Bobak D, Moorman J, Guanzon A, Gilmer L and Hahn C. (1997). Oncogene, 15, 2179-2189.
4. Bonifacino J, Dasso M, Harford J, Lippincott-Schwartz J and Yamada K. (2001). Current protocols in cell biology. New York: John Wiley and Sons, Inc.
5. Cance WG, Harris JE, Iacocca MV, Roche E, Yang X, Chang J, Simkins S and Xu L. (2000). Clin. Cancer Res., 6, 2417-2423.
6. Carsillo T, Astrinidis A and Henske EP. (2000). Proc. Natl. Acad. Sci. USA, 97, 6085-6090.
7. Clark EA, Golub TR, Lander ES and Hynes RO. (2000). Nature, 406, 532-535.
8. Dabora SL, Jozwiak S, Franz DN, Roberts PS, Nieto A, Chung J, Choy YS, Reeve MP, Thiele E, Egelhoff JC, Kasprzyk-Obara J, Domanska-Pakiela D and Kwiatkowski DJ. (2001). Am. J. Hum. Genet., 68, 64-80.
9. European chromosome 16 Tuberous Sclerosis Consortium. (1993). Cell, 75, 1305-1315.
10. Evers EE, Zondag GC, Malliri A, Price LS, ten Klooster JP, van der Kammen RA and Collard JG. (2000). Eur. J. Cancer, 36, 1269-1274.
11. Flinn HM and Ridley AJ. (1996). J. Cell Sci., 109, 1133-1141.
12. Gomez M, Sampson JR and Whittemore VH (eds). (1999). Tuberous Sclerosis Complex 3rd Edn. New York: Oxford University Press.
13. Henry KW, Yuan X, Koszewski NJ, Onda H, Kwiatkowski DJ and Noonan DJ. (1998). J. Biol. Chem., 273, 20535-20539.
14. Hodges AK, Li S, Maynard J, Parry L, Braverman R, Cheadle JP, DeClue JE and Sampson JR. (2001). Hum. Mol. Genet., 10, 2899-2905.
15. Howe SR, Gottardis MM, Everitt JI, Goldsworthy TL, Wolf DC and Walker C. (1995). Am. J. Pathol., 146, 1568-1579.
16. Ilic D, Damsky CH and Yamamoto T. (1997). J. Cell Sci., 110, 401-407.
17. Irani C, Goncharova EA, Hunter DS, Walker CL, Panettieri RA and Krymskaya VP. (2002). Am. J. Physiol. Lung Cell. Mol. Physiol., 282, L854-L862.
18. Ito N and Rubin GM. (1999). Cell, 96, 529-539.
19. Judson PL, He X, Cance WG and Van Le L. (1999). Cancer, 86, 1551-1556.
20. Kobayashi R, Hirayama Y, Kobayashi E, Kubo Y and Hino O. (1995). Nat. Genet., 9, 70-74.
21. Kornberg LJ. (1998). Head Neck, 20, 745-752.
22. Lamb RF, Roy C, Diefenbach TJ, Vinters HV, Johnson MW, Jay DG and Hall A. (2000). Nat. Cell. Biol., 2, 281-287.
23. Miloloza A, Rosner M, Nellist M, Halley D, Bernaschek G and Hengstschlager M. (2000). Hum. Mol. Genet., 9, 1721-1727.
24. Nellist M, Verhaaf B, Goedbloed MA, Reuser AJ, van Den Ouweland AM and Halley DJ. (2001). Hum. Mol. Genet., 10, 2889-2898.
25. Plank TL, Yeung RS and Henske EP. (1998). Cancer Res., 58, 4766-4770.
26. Potter CJ, Huang H and Xu T. (2001). Cell, 105, 357-368.
27. Reid T, Furuyashiki T, Ishizaki T, Watanabe G, Watanabe N, Fujisawa K, Morii N, Madaule P and Narumiya S. (1996). J. Biol. Chem., 271, 13556-13560.
28. Royal I, Lamarche-Vane N, Lamorte L, Kaibuchi K and Park M. (2000). Mol. Biol. Cell, 11, 1709-1725.
29. Sastry SK and Burridge K. (2000). Exp. Cell. Res., 261, 25-36.
30. Schmitz AA, Govek EE, Bottner B and Van Aelst L. (2000). Exp. Cell Res., 261, 1-12.
31. Sieg DJ, Hauck CR, Ilic D, Klingbeil CK, Schaefer E, Damsky CH and Schlaepfer DD. (2000). Nat. Cell. Biol., 2, 249-256.
32. Sinnett-Smith J, Lunn JA, Leopoldt D and Rozengurt E. (2001). Exp. Cell Res., 266, 292-302.
33. Soucek T, Pusch O, Wienecke R, DeClue JE and Hengstschlager M. (1997). J. Biol. Chem., 272, 29301-29308.
34. Sullivan EJ. (1998). Chest, 114, 1689-1703.
35. Tapon N, Ito N, Dickson BJ, Treisman JE and Hariharan IK. (2001). Cell, 105, 345-355.
36. Timpson P, Jones GE, Frame MC and Brunton VG. (2001). Curr. Biol., 11, 1836-1846.
37. van Slegtenhorst M, de Hoogt R, Hermans C, Nellist M, Janssen B, Verhoef S, Lindhout D, van den Ouweland A, Halley D, Young J, Burley M, Jeremiah S, Woodward K, Nahmias J, Fox M, Ekong R, Osborne J, Wolfe J, Povey S, Snell R, Cheadle J, Jones A, Tachataki M, Ravine D, Sampson J, Reeve M, Richardson P, Wilmer R, Munro C, Hawkins T, Sepp T, Ali J, Ward S, Green A, Yates J, Kwiatkowska J, Henske E, Short M, Haines J, Jozwiak S and Kwiatkowski D. (1997). Science, 277, 805-808.
38. van Slegtenhorst M, Nellist M, Nagelkerken B, Cheadle J, Snell R, van den Ouweland A, Reuser A, Sampson J, Halley D and van der Sluijs P. (1998). Hum. Mol. Genet., 7, 1053-1057.
39. Weiner TM, Liu ET, Craven RJ and Cance WG. (1993). Lancet, 342, 1024-1025.
40. Wienecke R, Konig A and DeClue JE. (1995). J. Biol. Chem., 270, 16409-16414.
41. Xiao GH, Shoarinejad F, Jin F, Golemis EA and Yeung RS. (1997). J. Biol. Chem., 272, 6097-6100.
42. Yeung RS, Xiao GH, Everitt JI, Jin F and Walker CL. (1995). Mol. Carcinog., 14, 28-36.
43. Yeung RS, Xiao GH, Jin F, Lee WC, Testa JR and Knudson AG. (1994). Proc. Natl. Acad. Sci. USA, 91, 11413-11416.
44. Yu J, Astrinidis A and Henske EP. (2001). Am. J. Respir. Crit. Care Med., 164, 1537-1540.