Structures of the G85R variant of SOD1 in familial amyotrophic lateral sclerosis

Journal of Biological Chemistry

Volumn 283, Issue 23, 2008, Pages 16169-16177

  Cao, Xiaohang ^a   Antonyuk, Svetlana V ^b   Seetharaman, Sai V ^a   Whitson, Lisa J ^a   Taylor, Alexander B ^a   Holloway, Stephen P ^a   Strange, Richard W ^b   Doucette, Peter A ^c   Valentine, Joan Selverstone ^c   Tiwari, Ashutosh ^d   Hayward, Lawrence J ^d   Padua, Shelby ^e   Cohlberg, Jeffrey A ^e   Hasnain, S Samar ^b   Hart, P John ^a  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b DARESBURY LABORATORY   (United Kingdom)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^e CALIFORNIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL CULTURE; COPPER; GENE ENCODING; METAL IONS; METAL REFINING; OXYGEN; PLANTS (BOTANY); SINGLE CRYSTALS; TOXICITY; ZINC;

AMYOTROPHIC LATERAL SCLEROSES; BINDING LOOPS; CENTRAL NERVOUS SYSTEMS; ION DEFICIENCIES; MISFOLDING; MOLECULAR BASES; MOTOR NEURONS; NEURAL TISSUES; NEURODEGENERATIVE DISEASES; SINGLE CRYSTAL X-RAY DIFFRACTIONS; SUPEROXIDE DISMUTASE; TRANSGENIC MOUSE; WILD TYPES;

STRUCTURAL METALS;

COPPER ZINC SUPEROXIDE DISMUTASE; ZINC; RECOMBINANT PROTEIN; SUPEROXIDE DISMUTASE;

AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; BINDING SITE; CENTRAL NERVOUS SYSTEM; COPPER DEFICIENCY; GENETIC VARIABILITY; METAL BINDING; PRIORITY JOURNAL; PROTEIN STRUCTURE; SUBSTITUTION REACTION; TRANSGENIC MOUSE; X RAY DIFFRACTION; ZINC DEFICIENCY; AMINO ACID SUBSTITUTION; ANIMAL; CHEMISTRY; ENZYMOLOGY; GENETICS; HUMAN; METABOLISM; MOTONEURON; MOUSE; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

MUS MUSCULUS;

AMINO ACID SUBSTITUTION; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; HUMANS; MICE; MICE, TRANSGENIC; MOTOR NEURONS; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; SUPEROXIDE DISMUTASE;

EID: 47049120538     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M801522200     Document Type: Article

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