Subunit asymmetry in the three-dimensional structure of a human CuZnSOD mutant found in familial amyotrophic lateral sclerosis

Protein Science

Volumn 7, Issue 3, 1998, Pages 545-555

  Hart, P John ^a   Liu, Hongbin ^a   Pellegrini, Matteo ^a   Nersissian, Aram M ^a   Gralla, Edith B ^a   Valentine, Joan S ^a   Eisenberg, David ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Amyotrophic lateral sclerosis; Apoptosis; Lou Gehrig's disease; Motor neuron; Neurodegeneration; Oxidative damage; Superoxide dismutase; X ray crystallography

Indexed keywords

COPPER ION; COPPER ZINC SUPEROXIDE DISMUTASE; MUTANT PROTEIN; PROTEIN SUBUNIT;

AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CHROMOSOME 21; CRYSTAL STRUCTURE; ENZYME CONFORMATION; ENZYME SUBUNIT; FAMILIAL DISEASE; GENE MUTATION; HUMAN; MOTONEURON; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN STABILITY; X RAY CRYSTALLOGRAPHY;

EID: 0031911637     PISSN: 09618368     EISSN: None     Source Type: Journal    
DOI: 10.1002/pro.5560070302     Document Type: Article

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