메뉴 건너뛰기




Volumn 8, Issue 4, 2008, Pages 465-477

Apical junction complex proteins and ulcerative colitis: A focus on the PTPRS gene

Author keywords

Adherens junction; Apical junction complex; Crohn's disease; Inflammatory bowel disease; Protein tyrosine phosphatase; PTPo ; PTPRS; Ulcerative colitis

Indexed keywords

CASPASE RECRUITMENT DOMAIN PROTEIN 15; INTERLEUKIN 12; INTERLEUKIN 23; MULTIDRUG RESISTANCE PROTEIN 1; MYOSIN; PROTEIN TYROSINE PHOSPHATASE EPSILON; TUMOR NECROSIS FACTOR ALPHA; UVOMORULIN;

EID: 46949101655     PISSN: 14737159     EISSN: 17448352     Source Type: Journal    
DOI: 10.1586/14737159.8.4.465     Document Type: Review
Times cited : (8)

References (170)
  • 1
    • 35648958802 scopus 로고    scopus 로고
    • Diagnostics of inflammatory bowel disease
    • Nikolaus S, Schreiber S. Diagnostics of inflammatory bowel disease. Gastroenterology 133(5), 1670-1689 (2007).
    • (2007) Gastroenterology , vol.133 , Issue.5 , pp. 1670-1689
    • Nikolaus, S.1    Schreiber, S.2
  • 2
    • 1842482789 scopus 로고    scopus 로고
    • Diagnostic role and clinical correlates of anti-Saccharomyces cerevisiae antibodies (ASCA) and anti-neutrophil cytoplasmic antibodies (p-ANCA) in Italian patients with inflammatory bowel diseases
    • Saibeni S, Folli C, de Franchis R, Borsi G, Vecchi M. Diagnostic role and clinical correlates of anti-Saccharomyces cerevisiae antibodies (ASCA) and anti-neutrophil cytoplasmic antibodies (p-ANCA) in Italian patients with inflammatory bowel diseases. Dig. Liver Dis. 35(12), 862-868 (2003).
    • (2003) Dig. Liver Dis , vol.35 , Issue.12 , pp. 862-868
    • Saibeni, S.1    Folli, C.2    de Franchis, R.3    Borsi, G.4    Vecchi, M.5
  • 3
    • 33745822075 scopus 로고    scopus 로고
    • Analysis of serum antibodies in patients suspected of having inflammatory bowel disease
    • Jaskowski TD, Litwin CM, Hill HR. Analysis of serum antibodies in patients suspected of having inflammatory bowel disease. Clin. Vaccine Immunol. 13(6), 655-660 (2006).
    • (2006) Clin. Vaccine Immunol , vol.13 , Issue.6 , pp. 655-660
    • Jaskowski, T.D.1    Litwin, C.M.2    Hill, H.R.3
  • 4
    • 0033227691 scopus 로고    scopus 로고
    • Measurement of pANCA (antineutrophil cytoplasmic antibodies) and ASCA (anti-Saccharomyces cerevisiae) in screening for IBD in young children
    • Kugathasan S, Werlin SL. Measurement of pANCA (antineutrophil cytoplasmic antibodies) and ASCA (anti-Saccharomyces cerevisiae) in screening for IBD in young children. Inflamm. Bowel Dis. 5(4), 283-284(1999).
    • (1999) Inflamm. Bowel Dis , vol.5 , Issue.4 , pp. 283-284
    • Kugathasan, S.1    Werlin, S.L.2
  • 5
    • 0036893658 scopus 로고    scopus 로고
    • Pseudomonas fluorescens encodes the Crohn's disease-associated 12 sequence and T-cell superantigen
    • Wei B, Huang T, Dalwadi H, Sutton CL, Bruckner D, Braun J. Pseudomonas fluorescens encodes the Crohn's disease-associated 12 sequence and T-cell superantigen. Infect. Immun. 70(12), 6567-6575 (2002).
    • (2002) Infect. Immun , vol.70 , Issue.12 , pp. 6567-6575
    • Wei, B.1    Huang, T.2    Dalwadi, H.3    Sutton, C.L.4    Bruckner, D.5    Braun, J.6
  • 6
    • 0034235501 scopus 로고    scopus 로고
    • Identification of a novel bacterial sequence associated with Crohn's disease
    • Sutton CL, Kim J, Yamane A et al. Identification of a novel bacterial sequence associated with Crohn's disease. Gastroenterology 119(1), 23-31 (2000).
    • (2000) Gastroenterology , vol.119 , Issue.1 , pp. 23-31
    • Sutton, C.L.1    Kim, J.2    Yamane, A.3
  • 7
    • 8744262944 scopus 로고    scopus 로고
    • Serologic testing with ANCA, ASCA, and anti-OmpC in children and young adults with Crohn's disease and ulcerative colitis: Diagnostic value and correlation with disease phenotype
    • Zholudev A, Zurakowski D, Young W, Leichtner A, Bousvaros A. Serologic testing with ANCA, ASCA, and anti-OmpC in children and young adults with Crohn's disease and ulcerative colitis: diagnostic value and correlation with disease phenotype. Am. J. Gastroenterol. 99(11), 2235-2241 (2004).
    • (2004) Am. J. Gastroenterol , vol.99 , Issue.11 , pp. 2235-2241
    • Zholudev, A.1    Zurakowski, D.2    Young, W.3    Leichtner, A.4    Bousvaros, A.5
  • 8
    • 2342646956 scopus 로고    scopus 로고
    • Bacterial flagellin is a dominant antigen in Crohn disease
    • Lodes MJ, Cong Y, Elson CO et al. Bacterial flagellin is a dominant antigen in Crohn disease. J. Clin. Invest. 113(9), 1296-1306 (2004).
    • (2004) J. Clin. Invest , vol.113 , Issue.9 , pp. 1296-1306
    • Lodes, M.J.1    Cong, Y.2    Elson, C.O.3
  • 9
    • 20444441016 scopus 로고    scopus 로고
    • Antibodies to CBirl flagellin define a unique response that is associated independently with complicated Crohn's disease
    • Targan SR, Landers CJ, Yang H et al. Antibodies to CBirl flagellin define a unique response that is associated independently with complicated Crohn's disease. Gastroenterology 128(7), 2020-2028 (2005).
    • (2005) Gastroenterology , vol.128 , Issue.7 , pp. 2020-2028
    • Targan, S.R.1    Landers, C.J.2    Yang, H.3
  • 10
    • 33847383306 scopus 로고    scopus 로고
    • Calprotectin and lactoferrin in the assessment of intestinal inflammation and organic disease
    • D'Inca R, Dal Pont E, Di Leo V et al. Calprotectin and lactoferrin in the assessment of intestinal inflammation and organic disease. Int. J. Colorectal Dis. 11(4), 429-437 (2007).
    • (2007) Int. J. Colorectal Dis , vol.11 , Issue.4 , pp. 429-437
    • D'Inca, R.1    Dal Pont, E.2    Di Leo, V.3
  • 11
    • 36549001139 scopus 로고    scopus 로고
    • The prevalence and geographic distribution of Crohn's disease and ulcerative colitis in the United States
    • Kappelman MD, Rifas-Shiman SL, Kleinman K et al. The prevalence and geographic distribution of Crohn's disease and ulcerative colitis in the United States. Clin. Gastroenterol. Hepatol. 5(12), 1424-1429 (2007).
    • (2007) Clin. Gastroenterol. Hepatol , vol.5 , Issue.12 , pp. 1424-1429
    • Kappelman, M.D.1    Rifas-Shiman, S.L.2    Kleinman, K.3
  • 12
    • 33745775434 scopus 로고    scopus 로고
    • Mechanisms of disease: Pathogenesis of Crohn's disease and ulcerative colitis
    • Sartor RB. Mechanisms of disease: pathogenesis of Crohn's disease and ulcerative colitis. Nat. Clin. Pract. Gastroenterol. Hepatol. 3(7), 390-407 (2006).
    • (2006) Nat. Clin. Pract. Gastroenterol. Hepatol , vol.3 , Issue.7 , pp. 390-407
    • Sartor, R.B.1
  • 13
    • 0035978651 scopus 로고    scopus 로고
    • Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
    • Hugot JP, Chamaillard M, Zouali H et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 41 (6837), 599-603 (2001).
    • (2001) Nature , vol.41 , Issue.6837 , pp. 599-603
    • Hugot, J.P.1    Chamaillard, M.2    Zouali, H.3
  • 14
    • 34247554965 scopus 로고    scopus 로고
    • Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
    • Rioux JD, Xavier RJ, Taylor KD et al. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat. Genet. 39(5), 596-604 (2007).
    • (2007) Nat. Genet , vol.39 , Issue.5 , pp. 596-604
    • Rioux, J.D.1    Xavier, R.J.2    Taylor, K.D.3
  • 15
    • 33845340501 scopus 로고    scopus 로고
    • A genome-wide association study identities IL23R as an inflammatory bowel disease gene
    • Duerr RH, Taylor KD, Brant SR et al. A genome-wide association study identities IL23R as an inflammatory bowel disease gene. Science 314(5804), 1461-1463 (2006).
    • (2006) Science , vol.314 , Issue.5804 , pp. 1461-1463
    • Duerr, R.H.1    Taylor, K.D.2    Brant, S.R.3
  • 16
    • 84969213492 scopus 로고    scopus 로고
    • 000 cases of seven common diseases and 3,000 shared controls
    • Genome-wide association study of 14
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447(7145), 661-678 (2007).
    • (2007) Nature , vol.447 , Issue.7145 , pp. 661-678
  • 17
    • 34447306637 scopus 로고    scopus 로고
    • Protein-tyrosine phosphatase σ is associated with ulcerative colitis
    • Muise AM, Walters T, Wine E et al. Protein-tyrosine phosphatase σ is associated with ulcerative colitis. Curr. Biol. 17(14), 1212-1218 (2007).
    • (2007) Curr. Biol , vol.17 , Issue.14 , pp. 1212-1218
    • Muise, A.M.1    Walters, T.2    Wine, E.3
  • 18
    • 21744442434 scopus 로고    scopus 로고
    • Association of DLG5 R30Q variant with inflammatory bowel disease
    • Daly MJ, Pearce AV, Farwell L et al. Association of DLG5 R30Q variant with inflammatory bowel disease. Eur. J. Hum. Genet. 13(7), 835-839 (2005).
    • (2005) Eur. J. Hum. Genet , vol.13 , Issue.7 , pp. 835-839
    • Daly, M.J.1    Pearce, A.V.2    Farwell, L.3
  • 19
    • 0035978533 scopus 로고    scopus 로고
    • A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
    • Ogura Y, Bonen DK, Inohara N et al. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 411(6837), 603-606 (2001).
    • (2001) Nature , vol.411 , Issue.6837 , pp. 603-606
    • Ogura, Y.1    Bonen, D.K.2    Inohara, N.3
  • 20
    • 0012722659 scopus 로고    scopus 로고
    • Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection
    • Girardin SE, Boneca IG, Viala J et al. Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection. J. Biol. Chem. 278(11), 8869-8872 (2003).
    • (2003) J. Biol. Chem , vol.278 , Issue.11 , pp. 8869-8872
    • Girardin, S.E.1    Boneca, I.G.2    Viala, J.3
  • 21
    • 13244277880 scopus 로고    scopus 로고
    • Nod2 mutation in Crohn's disease potentiates NF-KB activity and IL-1β processing
    • Maeda S, Hsu LC, Liu H et al. Nod2 mutation in Crohn's disease potentiates NF-KB activity and IL-1β processing. Science 307(5710), 734-738 (2005).
    • (2005) Science , vol.307 , Issue.5710 , pp. 734-738
    • Maeda, S.1    Hsu, L.C.2    Liu, H.3
  • 22
    • 10744222688 scopus 로고    scopus 로고
    • Expression of NOD2 in Paneth cells: A possible link to Crohn's ileitis
    • Ogura Y, Lala S, Xin W et al. Expression of NOD2 in Paneth cells: a possible link to Crohn's ileitis. Gut 52(11), 1591-1597 (2003).
    • (2003) Gut , vol.52 , Issue.11 , pp. 1591-1597
    • Ogura, Y.1    Lala, S.2    Xin, W.3
  • 23
    • 0038109983 scopus 로고    scopus 로고
    • Crohn's disease and the NOD2 gene: A role for paneth cells
    • Lala S, Ogura Y, Osborne C et al. Crohn's disease and the NOD2 gene: a role for paneth cells. Gastroenterology 125(1), 47-57 (2003).
    • (2003) Gastroenterology , vol.125 , Issue.1 , pp. 47-57
    • Lala, S.1    Ogura, Y.2    Osborne, C.3
  • 24
    • 11144279151 scopus 로고    scopus 로고
    • Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: A metaanalysis
    • Economou M, Trikalinos TA, Loizou KT, Tsianos EV, Ioannidis JP Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: a metaanalysis. Am. J. Gastroenterol. 99(12), 2393-2404 (2004).
    • (2004) Am. J. Gastroenterol , vol.99 , Issue.12 , pp. 2393-2404
    • Economou, M.1    Trikalinos, T.A.2    Loizou, K.T.3    Tsianos, E.V.4    Ioannidis, J.P.5
  • 25
    • 33748999808 scopus 로고    scopus 로고
    • 15/NOD2 mutations in Crohn's disease
    • Hugot JP. CARD 15/NOD2 mutations in Crohn's disease. Ann. NY Acad. Sci. 1072, 9-18 (2006).
    • (2006) Ann. NY Acad. Sci , vol.1072 , pp. 9-18
    • Hugot, J.C.1
  • 26
    • 2442585704 scopus 로고    scopus 로고
    • Functional variants of OCTN cation transporter genes are associated with Crohn disease
    • Peltekova VD, Wintle RF, Rubin LA et al. Functional variants of OCTN cation transporter genes are associated with Crohn disease. Nat. Genet. 36(5), 471-475 (2004).
    • (2004) Nat. Genet , vol.36 , Issue.5 , pp. 471-475
    • Peltekova, V.D.1    Wintle, R.F.2    Rubin, L.A.3
  • 27
    • 33847212513 scopus 로고    scopus 로고
    • Refined genomic localization and ethnic differences observed for the IBD5 association with Crohn's disease
    • Silverberg MS, Duerr RH, Brant SR et al. Refined genomic localization and ethnic differences observed for the IBD5 association with Crohn's disease. Eur. J. Hum. Genet. 15(3), 328-335 (2007).
    • (2007) Eur. J. Hum. Genet , vol.15 , Issue.3 , pp. 328-335
    • Silverberg, M.S.1    Duerr, R.H.2    Brant, S.R.3
  • 28
    • 2442519456 scopus 로고    scopus 로고
    • Genetic variation in DLG5 is associated with inflammatory bowel disease
    • Stoll M, Corneliussen B, Costello CM et al. Genetic variation in DLG5 is associated with inflammatory bowel disease. Nat. Genet. 36(5), 476-480 (2004).
    • (2004) Nat. Genet , vol.36 , Issue.5 , pp. 476-480
    • Stoll, M.1    Corneliussen, B.2    Costello, C.M.3
  • 29
    • 9144224852 scopus 로고    scopus 로고
    • MDR1 Ala893 polymorphism is associated with inflammatory bowel disease
    • Brant SR, Panhuysen CI, Nicolae D et al. MDR1 Ala893 polymorphism is associated with inflammatory bowel disease. Am. J. Hum. Genet. 73(6), 1282-1292 (2003).
    • (2003) Am. J. Hum. Genet , vol.73 , Issue.6 , pp. 1282-1292
    • Brant, S.R.1    Panhuysen, C.I.2    Nicolae, D.3
  • 31
    • 18244395058 scopus 로고    scopus 로고
    • The mdrla-/- mouse model of spontaneous colitis: A relevant and appropriate animal model to study inflammatory bowel disease
    • Wilk JN, Bilsborough J, Viney JL. The mdrla-/- mouse model of spontaneous colitis: a relevant and appropriate animal model to study inflammatory bowel disease. Immunol. Res. 31(2), 151-159 (2005).
    • (2005) Immunol. Res , vol.31 , Issue.2 , pp. 151-159
    • Wilk, J.N.1    Bilsborough, J.2    Viney, J.L.3
  • 32
    • 8744300643 scopus 로고    scopus 로고
    • Macroscopic, microscopic and biochemical characterisation of spontaneous colitis in a transgenic mouse, deficient in the multiple drug resistance 1 a gene
    • Banner KH, Cattaneo C, Le Net JL, Popovic A, Collins D, Gale JD. Macroscopic, microscopic and biochemical characterisation of spontaneous colitis in a transgenic mouse, deficient in the multiple drug resistance 1 a gene. Br. J. Pharmacol. 143(5), 590-598 (2004).
    • (2004) Br. J. Pharmacol , vol.143 , Issue.5 , pp. 590-598
    • Banner, K.H.1    Cattaneo, C.2    Le Net, J.L.3    Popovic, A.4    Collins, D.5    Gale, J.D.6
  • 33
    • 37249034766 scopus 로고    scopus 로고
    • Systematic association mapping identifies NELL 1 as a novel IBD disease gene
    • Franke A, Hampe J, Rosenstiel P et al. Systematic association mapping identifies NELL 1 as a novel IBD disease gene. PLoS ONE 2,E691 (2007).
    • (2007) PLoS ONE , vol.2
    • Franke, A.1    Hampe, J.2    Rosenstiel, P.3
  • 34
    • 33846627302 scopus 로고    scopus 로고
    • A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
    • Hampe J, Franke A, Rosenstiel P et al. A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nat. Genet. 39(2), 207-211 (2007).
    • (2007) Nat. Genet , vol.39 , Issue.2 , pp. 207-211
    • Hampe, J.1    Franke, A.2    Rosenstiel, P.3
  • 35
    • 34247579326 scopus 로고    scopus 로고
    • Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p l3.1 and modulates expression of PTGER4
    • Libioulle C, Louis E, Hansoul S et al. Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p l3.1 and modulates expression of PTGER4. PLoS Genet. 3(4), E58 (2007).
    • (2007) PLoS Genet , vol.3 , Issue.4
    • Libioulle, C.1    Louis, E.2    Hansoul, S.3
  • 36
    • 34347338690 scopus 로고    scopus 로고
    • Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility
    • Parkes M, Barrett JC, Prescott NJ et al. Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility. Nat. Genet. 39(7), 830-832 (2007).
    • (2007) Nat. Genet , vol.39 , Issue.7 , pp. 830-832
    • Parkes, M.1    Barrett, J.C.2    Prescott, N.J.3
  • 37
    • 35548958718 scopus 로고    scopus 로고
    • Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci
    • Raelson JV, Little RD, Ruether A et al. Genome-wide association study for Crohn's disease in the Quebec Founder Population identifies multiple validated disease loci. Proc. Natl Acad. Sci. USA 104(37), 14747-14752 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , Issue.37 , pp. 14747-14752
    • Raelson, J.V.1    Little, R.D.2    Ruether, A.3
  • 38
    • 27944464550 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease
    • Yamazaki K, McGovern D, Ragoussis J et al. Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease. Hum. Mol Genet. 14(22), 3499-3506 (2005).
    • (2005) Hum. Mol Genet , vol.14 , Issue.22 , pp. 3499-3506
    • Yamazaki, K.1    McGovern, D.2    Ragoussis, J.3
  • 39
    • 34247560627 scopus 로고    scopus 로고
    • IL23R variation determines susceptibility but not disease phenotype in inflammatory bowel disease
    • Tremelling M, Cummings F, Fisher SA et al. IL23R variation determines susceptibility but not disease phenotype in inflammatory bowel disease. Gastroenterology 132(5), 1657-1664 (2007).
    • (2007) Gastroenterology , vol.132 , Issue.5 , pp. 1657-1664
    • Tremelling, M.1    Cummings, F.2    Fisher, S.A.3
  • 40
    • 34347357508 scopus 로고    scopus 로고
    • Association analysis of genetic variants in IL23R, ATG16L1 and 5p13.1 loci with Crohn's disease in Japanese patients
    • Yamazaki K, Onouchi Y, Takazoe M, Kubo M, Nakamura Y, Hata A. Association analysis of genetic variants in IL23R, ATG16L1 and 5p13.1 loci with Crohn's disease in Japanese patients. J. Hum. Genet. 52(7), 575-583 (2007).
    • (2007) J. Hum. Genet , vol.52 , Issue.7 , pp. 575-583
    • Yamazaki, K.1    Onouchi, Y.2    Takazoe, M.3    Kubo, M.4    Nakamura, Y.5    Hata, A.6
  • 41
    • 35748981184 scopus 로고    scopus 로고
    • Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants
    • Burton PR, Clayton DG, Cardon LR et al. Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat. Genet. 39(11), 1329-1337 (2007).
    • (2007) Nat. Genet , vol.39 , Issue.11 , pp. 1329-1337
    • Burton, P.R.1    Clayton, D.G.2    Cardon, L.R.3
  • 42
    • 36849085953 scopus 로고    scopus 로고
    • The autoimmune disease-associated IL12B and IL23R polymorphisms in multiple sclerosis
    • Begovich AB, Chang M, Caillier SJ et al. The autoimmune disease-associated IL12B and IL23R polymorphisms in multiple sclerosis. Hum. Immunol. 68(11), 934-937 (2007).
    • (2007) Hum. Immunol , vol.68 , Issue.11 , pp. 934-937
    • Begovich, A.B.1    Chang, M.2    Caillier, S.J.3
  • 43
    • 34948840330 scopus 로고    scopus 로고
    • The IL23 axis plays a key role in the pathogenesis of IBD
    • McGovern D, Powrie E The IL23 axis plays a key role in the pathogenesis of IBD. Gut 56(10), 1333-1336(2007).
    • (2007) Gut , vol.56 , Issue.10 , pp. 1333-1336
    • McGovern, D.1    Powrie, E.2
  • 44
    • 33748506089 scopus 로고    scopus 로고
    • Human IRGM induces autophagy to eliminate intracellular mycobacteria
    • Singh SB, Davis AS, Taylor GA, Deretic V. Human IRGM induces autophagy to eliminate intracellular mycobacteria. Science 313(5792), 1438-1441 (2006).
    • (2006) Science , vol.313 , Issue.5792 , pp. 1438-1441
    • Singh, S.B.1    Davis, A.S.2    Taylor, G.A.3    Deretic, V.4
  • 45
    • 0034525596 scopus 로고    scopus 로고
    • Barrier dysfunction and Crohn's disease
    • Meddings J. Barrier dysfunction and Crohn's disease. Ann. NY Acad. Sci. 915, 333-338 (2000).
    • (2000) Ann. NY Acad. Sci , vol.915 , pp. 333-338
    • Meddings, J.1
  • 46
    • 0024267211 scopus 로고
    • Crohn's disease - a permeability disorder of the tight junction?
    • Hollander D. Crohn's disease - a permeability disorder of the tight junction? Gut 29(12), 1621-1624 (1988).
    • (1988) Gut , vol.29 , Issue.12 , pp. 1621-1624
    • Hollander, D.1
  • 47
    • 33845965299 scopus 로고    scopus 로고
    • Inflammatory bowel disease: Is it really just another break in the wall?
    • Weber CR, Turner JR. Inflammatory bowel disease: is it really just another break in the wall? Gut 56(1), 6-8 (2007).
    • (2007) Gut , vol.56 , Issue.1 , pp. 6-8
    • Weber, C.R.1    Turner, J.R.2
  • 48
    • 33749186777 scopus 로고    scopus 로고
    • Alterations in intestinal permeability
    • Arrieta MC, Bistritz L, Meddings JB. Alterations in intestinal permeability. Gut 55(10), 1512-1520(2006).
    • (2006) Gut , vol.55 , Issue.10 , pp. 1512-1520
    • Arrieta, M.C.1    Bistritz, L.2    Meddings, J.B.3
  • 49
    • 0033635128 scopus 로고    scopus 로고
    • Abnormal intestinal permeability predicts relapse in inactive Crohn disease
    • Arnott ID, Kingstone K, Ghosh S. Abnormal intestinal permeability predicts relapse in inactive Crohn disease. Scand. J. Gastroenterol. 35(11), 1163-1169 (2000).
    • (2000) Scand. J. Gastroenterol , vol.35 , Issue.11 , pp. 1163-1169
    • Arnott, I.D.1    Kingstone, K.2    Ghosh, S.3
  • 50
    • 0030777331 scopus 로고    scopus 로고
    • Increased gastric and intestinal permeability in patients with Crohn's disease
    • Wyatt J, Oberhuber G, Pongratz S et al. Increased gastric and intestinal permeability in patients with Crohn's disease. Am. J. Gastroenterol. 92(10), 1891-1896 (1997).
    • (1997) Am. J. Gastroenterol , vol.92 , Issue.10 , pp. 1891-1896
    • Wyatt, J.1    Oberhuber, G.2    Pongratz, S.3
  • 51
    • 0027217379 scopus 로고
    • Intestinal permeability and the prediction of relapse in Crohn's disease
    • Wyatt J, Vogelsang H, Hubl W, Waldhoer T, Lochs H. Intestinal permeability and the prediction of relapse in Crohn's disease. Lancet 341(8858), 1437-1439 (1993).
    • (1993) Lancet , vol.341 , Issue.8858 , pp. 1437-1439
    • Wyatt, J.1    Vogelsang, H.2    Hubl, W.3    Waldhoer, T.4    Lochs, H.5
  • 52
    • 34249933089 scopus 로고    scopus 로고
    • Altered permeability in inflammatory bowel disease: Pathophysiology and clinical implications
    • Mankertz J, Schulzke JD. Altered permeability in inflammatory bowel disease: pathophysiology and clinical implications. Curr. Opin. Gastroenterol. 23(4), 379-383 (2007).
    • (2007) Curr. Opin. Gastroenterol , vol.23 , Issue.4 , pp. 379-383
    • Mankertz, J.1    Schulzke, J.D.2
  • 53
    • 0034465898 scopus 로고    scopus 로고
    • Increased intestinal permeability precedes the onset of Crohn's disease in a subject with familial risk
    • Irvine EJ, Marshall JK. Increased intestinal permeability precedes the onset of Crohn's disease in a subject with familial risk. Gastroenterology 119(6), 1740-1744 (2000).
    • (2000) Gastroenterology , vol.119 , Issue.6 , pp. 1740-1744
    • Irvine, E.J.1    Marshall, J.K.2
  • 54
    • 0027293439 scopus 로고
    • Is small intestinal permeability really increased in relatives of patients with Crohn's disease?
    • May GR, Sutherland LR, Meddings JB. Is small intestinal permeability really increased in relatives of patients with Crohn's disease? Gastroenterology 104(6), 1627-1632(1993).
    • (1993) Gastroenterology , vol.104 , Issue.6 , pp. 1627-1632
    • May, G.R.1    Sutherland, L.R.2    Meddings, J.B.3
  • 55
    • 13844312631 scopus 로고    scopus 로고
    • The epithelium in inflammatory bowel disease: Potential role of endocytosis of junctional proteins in barrier disruption
    • discussion 24-32, 211-218
    • Ivanov AI, Nusrat A, Parkos CA. The epithelium in inflammatory bowel disease: potential role of endocytosis of junctional proteins in barrier disruption. Novartis Found. Symp. 263, 115-124; discussion 24-32, 211-218 (2004).
    • (2004) Novartis Found. Symp , vol.263 , pp. 115-124
    • Ivanov, A.I.1    Nusrat, A.2    Parkos, C.A.3
  • 56
    • 0028972499 scopus 로고
    • Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin
    • Hermiston ML, Gordon JI. Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin. Science 270(5239), 1203-1207 (1995).
    • (1995) Science , vol.270 , Issue.5239 , pp. 1203-1207
    • Hermiston, M.L.1    Gordon, J.I.2
  • 57
    • 33749007683 scopus 로고    scopus 로고
    • Inflammatory bowel disease and the apical junctional complex
    • Bruewer M, Samarin S, Nusrat A. Inflammatory bowel disease and the apical junctional complex. Ann. NY Acad. Sci. 1072, 242-252 (2006).
    • (2006) Ann. NY Acad. Sci , vol.1072 , pp. 242-252
    • Bruewer, M.1    Samarin, S.2    Nusrat, A.3
  • 58
    • 33144473772 scopus 로고    scopus 로고
    • Genetic basis for increased intestinal permeability in families with Crohn's disease: Role of CARD 15 3020insC mutation?
    • Buhner S, Buning C, Genschel J et al Genetic basis for increased intestinal permeability in families with Crohn's disease: role of CARD 15 3020insC mutation? Gut 55(3), 342-347 (2006).
    • (2006) Gut , vol.55 , Issue.3 , pp. 342-347
    • Buhner, S.1    Buning, C.2    Genschel, J.3
  • 59
    • 34249017939 scopus 로고    scopus 로고
    • Prevalence of CARD15/NOD2 mutations in Caucasian healthy people
    • Hugot JP, Zaccaria I, Cavanaugh J et al. Prevalence of CARD15/NOD2 mutations in Caucasian healthy people. Am. J. Gastroenterol. 102(6), 1259-1267(2007).
    • (2007) Am. J. Gastroenterol , vol.102 , Issue.6 , pp. 1259-1267
    • Hugot, J.P.1    Zaccaria, I.2    Cavanaugh, J.3
  • 60
    • 41149135384 scopus 로고    scopus 로고
    • Associations with tight junction genes Pard3 and Magi2 in Dutch patients point to a common barrier defect for celiac disease and ulcerative colitis
    • Wapenaar MC, Monsuur A, van Bodegraven A et al. Associations with tight junction genes Pard3 and Magi2 in Dutch patients point to a common barrier defect for celiac disease and ulcerative colitis. Gut 57, 463-467 (2008).
    • (2008) Gut , vol.57 , pp. 463-467
    • Wapenaar, M.C.1    Monsuur, A.2    van Bodegraven, A.3
  • 61
    • 36549070081 scopus 로고    scopus 로고
    • The MYO9B gene is a strong risk factor for developing refractory celiac disease
    • Wolters VM, Verbeek WH, Zhernakova A et al. The MYO9B gene is a strong risk factor for developing refractory celiac disease. Clin. Gastroenterol. Hepatol. 5(12), 1399-1405 (2007).
    • (2007) Clin. Gastroenterol. Hepatol , vol.5 , Issue.12 , pp. 1399-1405
    • Wolters, V.M.1    Verbeek, W.H.2    Zhernakova, A.3
  • 62
    • 28444452580 scopus 로고    scopus 로고
    • Myosin IXB variant increases the risk of celiac disease and points toward a primary intestinal barrier defect
    • Monsuur AJ, de Bakker PI, Alizadeh BZ et al. Myosin IXB variant increases the risk of celiac disease and points toward a primary intestinal barrier defect. Nat. Genet. 37(12), 1341-1344 (2005).
    • (2005) Nat. Genet , vol.37 , Issue.12 , pp. 1341-1344
    • Monsuur, A.J.1    de Bakker, P.I.2    Alizadeh, B.Z.3
  • 63
    • 37549053624 scopus 로고    scopus 로고
    • The association of MYO9B gene in Italian patients with inflammatory bowel diseases
    • Latiano A, Palmieri O, Valvano MR et al. The association of MYO9B gene in Italian patients with inflammatory bowel diseases. Aliment. Pharmacol. Ther. 27(3), 241-248 (2008).
    • (2008) Aliment. Pharmacol. Ther , vol.27 , Issue.3 , pp. 241-248
    • Latiano, A.1    Palmieri, O.2    Valvano, M.R.3
  • 64
    • 33845622964 scopus 로고    scopus 로고
    • Genetic variation in myosin IXB is associated with ulcerative colitis
    • van Bodegraven AA, Curley CR, Hunt KA et al. Genetic variation in myosin IXB is associated with ulcerative colitis. Gastroenterology 131(6), 1768-1774 (2006).
    • (2006) Gastroenterology , vol.131 , Issue.6 , pp. 1768-1774
    • van Bodegraven, A.A.1    Curley, C.R.2    Hunt, K.A.3
  • 65
    • 34548120887 scopus 로고    scopus 로고
    • MYO9B polymorphisms in patients with inflammatory bowel disease
    • Nunez C, Oliver J, Mendoza JL et al. MYO9B polymorphisms in patients with inflammatory bowel disease. Gut 56(9), 1321-1322 (2007).
    • (2007) Gut , vol.56 , Issue.9 , pp. 1321-1322
    • Nunez, C.1    Oliver, J.2    Mendoza, J.L.3
  • 66
    • 34247232108 scopus 로고    scopus 로고
    • The myosin IXb motor activity targets the myosin IXb RhoGAP domain as cargo to sites of actin polymerization
    • van den Boom F, Dussmann H, Uhlenbrock K, Abouhamed M, Bahler M. The myosin IXb motor activity targets the myosin IXb RhoGAP domain as cargo to sites of actin polymerization. Mol Biol. Cell. 18(4), 1507-1518 (2007).
    • (2007) Mol Biol. Cell , vol.18 , Issue.4 , pp. 1507-1518
    • van den Boom, F.1    Dussmann, H.2    Uhlenbrock, K.3    Abouhamed, M.4    Bahler, M.5
  • 67
    • 0037096161 scopus 로고    scopus 로고
    • Involvement of ASIP/PAR-3 in the promotion of epithelial tight junction formation
    • Hirose T, Izumi Y, Nagashima Y et al. Involvement of ASIP/PAR-3 in the promotion of epithelial tight junction formation. J. Cell Sci. 115(Pt 12), 2485-2495 (2002).
    • (2002) J. Cell Sci , vol.115 , Issue.PART 12 , pp. 2485-2495
    • Hirose, T.1    Izumi, Y.2    Nagashima, Y.3
  • 68
    • 14744289370 scopus 로고    scopus 로고
    • Par-3 controls tight junction assembly through the Rac exchange factor Tiaml
    • Chen X, Macara IG. Par-3 controls tight junction assembly through the Rac exchange factor Tiaml. Nat. Cell Biol. 7(3), 262-269 (2005).
    • (2005) Nat. Cell Biol , vol.7 , Issue.3 , pp. 262-269
    • Chen, X.1    Macara, I.G.2
  • 69
    • 33644530393 scopus 로고    scopus 로고
    • Par-3 mediates the inhibition of LIM kinase 2 to regulate cofilin phosphorylation and tight junction assembly
    • Chen X, Macara IG. Par-3 mediates the inhibition of LIM kinase 2 to regulate cofilin phosphorylation and tight junction assembly. J Cell Biol. 172(5), 671-678 (2006).
    • (2006) J Cell Biol , vol.172 , Issue.5 , pp. 671-678
    • Chen, X.1    Macara, I.G.2
  • 70
    • 39149135251 scopus 로고    scopus 로고
    • Downregulation of Par-3 expression and disruption of Par complex integrity by TGF-β during the process of epithelial to mesenchymal transition in rat proximal epithelial cells
    • Wang X, Nie J, Zhou Q et al. Downregulation of Par-3 expression and disruption of Par complex integrity by TGF-β during the process of epithelial to mesenchymal transition in rat proximal epithelial cells. Biochim. Biophys. Acta 1782(1), 51-59(2008).
    • (2008) Biochim. Biophys. Acta , vol.1782 , Issue.1 , pp. 51-59
    • Wang, X.1    Nie, J.2    Zhou, Q.3
  • 71
    • 0033873750 scopus 로고    scopus 로고
    • Identification of a novel β-catenin-interacting protein
    • Kawajiri A, Itoh N, Fukata M et al. Identification of a novel β-catenin-interacting protein. Biochem. Biophys. Res. Commun. 273(2), 712-717 (2000).
    • (2000) Biochem. Biophys. Res. Commun , vol.273 , Issue.2 , pp. 712-717
    • Kawajiri, A.1    Itoh, N.2    Fukata, M.3
  • 72
    • 14044261474 scopus 로고    scopus 로고
    • Vinculin controls PTEN protein level by maintaining the interaction of the adherens junction protein β-catenin with the scaffolding protein MAGI-2
    • Subauste MC, Nalbant P, Adamson ED, Hahn KM. Vinculin controls PTEN protein level by maintaining the interaction of the adherens junction protein β-catenin with the scaffolding protein MAGI-2. J Biol. Chem. 280(7), 5676-56781 (2005).
    • (2005) J Biol. Chem , vol.280 , Issue.7 , pp. 5676-56781
    • Subauste, M.C.1    Nalbant, P.2    Adamson, E.D.3    Hahn, K.M.4
  • 73
    • 34548167569 scopus 로고    scopus 로고
    • Failure of epithelial tube maintenance causes hydrocephalus and renal cysts in Dlg5-/-mice
    • Nechiporuk T, Fernandez TE, Vasioukhin V Failure of epithelial tube maintenance causes hydrocephalus and renal cysts in Dlg5-/-mice. Dev. Cell 13(3), 338-350 (2007).
    • (2007) Dev. Cell , vol.13 , Issue.3 , pp. 338-350
    • Nechiporuk, T.1    Fernandez, T.E.2    Vasioukhin, V.3
  • 74
    • 0035968259 scopus 로고    scopus 로고
    • A CD45 polymorphism associated with multiple sclerosis disrupts an exonic splicing silencer
    • Lynch KW, Weiss A. A CD45 polymorphism associated with multiple sclerosis disrupts an exonic splicing silencer. J Biol. Chem. 276(26), 24341-24347 (2001).
    • (2001) J Biol. Chem , vol.276 , Issue.26 , pp. 24341-24347
    • Lynch, K.W.1    Weiss, A.2
  • 75
    • 27344431756 scopus 로고    scopus 로고
    • Structure of the hematopoietic tyrosine phosphatase (HePTP) catalytic domain: Structure of a KIM phosphatase with phosphate bound at the active site
    • Mustelin T, Tautz L, Page R. Structure of the hematopoietic tyrosine phosphatase (HePTP) catalytic domain: structure of a KIM phosphatase with phosphate bound at the active site. J Mol. Biol. 354(1), 150-163 (2005).
    • (2005) J Mol. Biol , vol.354 , Issue.1 , pp. 150-163
    • Mustelin, T.1    Tautz, L.2    Page, R.3
  • 76
    • 33750299450 scopus 로고    scopus 로고
    • Protein tyrosine phosphatases: From genes, to function, to disease
    • Tonks NK. Protein tyrosine phosphatases: from genes, to function, to disease. Nat. Rev. Mol. Cell Biol. 7(11), 833-846 (2006).
    • (2006) Nat. Rev. Mol. Cell Biol , vol.7 , Issue.11 , pp. 833-846
    • Tonks, N.K.1
  • 77
    • 16844386333 scopus 로고    scopus 로고
    • Functional significance of the LAR receptor protein tyrosine phosphatase family in development and diseases
    • Chagnon MJ, Uetani N, Tremblay ML. Functional significance of the LAR receptor protein tyrosine phosphatase family in development and diseases. Biochem. Cell Biol. 82(6), 664-675 (2004).
    • (2004) Biochem. Cell Biol , vol.82 , Issue.6 , pp. 664-675
    • Chagnon, M.J.1    Uetani, N.2    Tremblay, M.L.3
  • 78
    • 0035910603 scopus 로고    scopus 로고
    • The dual-specificity phosphatase MKP-1 limits the cardiac hypertrophic response in vitro and in vitro
    • Bueno OF, De Windt LJ, Lim HW et al. The dual-specificity phosphatase MKP-1 limits the cardiac hypertrophic response in vitro and in vitro. Circ. Res. 88(1), 88-96 (2001).
    • (2001) Circ. Res , vol.88 , Issue.1 , pp. 88-96
    • Bueno, O.F.1    De Windt, L.J.2    Lim, H.W.3
  • 79
    • 33847636046 scopus 로고    scopus 로고
    • Vascular endothelial tyrosine phosphatase (VE-PTP)-null mice undergo vasculogenesis but die embryonically because of defects in angiogenesis
    • Dominguez MG, Hughes VC, Pan L et al. Vascular endothelial tyrosine phosphatase (VE-PTP)-null mice undergo vasculogenesis but die embryonically because of defects in angiogenesis. Proc. Natl Acad. Sci. USA 104(9), 3243-3248 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , Issue.9 , pp. 3243-3248
    • Dominguez, M.G.1    Hughes, V.C.2    Pan, L.3
  • 80
    • 23044445669 scopus 로고    scopus 로고
    • Regulation of NMDA receptor trafficking by amyloid-β
    • Snyder EM, Nong Y, Almeida CG et al. Regulation of NMDA receptor trafficking by amyloid-β. Nat. Neurosci. 8(8), 1051-1058 (2005).
    • (2005) Nat. Neurosci , vol.8 , Issue.8 , pp. 1051-1058
    • Snyder, E.M.1    Nong, Y.2    Almeida, C.G.3
  • 81
    • 0033662317 scopus 로고    scopus 로고
    • A point mutation in PTPRC is associated with the development of multiple sclerosis
    • Jacobsen M, Schweer D, Ziegler A et al. A point mutation in PTPRC is associated with the development of multiple sclerosis. Nat. Genet. 26(4), 495-499 (2000).
    • (2000) Nat. Genet , vol.26 , Issue.4 , pp. 495-499
    • Jacobsen, M.1    Schweer, D.2    Ziegler, A.3
  • 82
    • 0037370481 scopus 로고    scopus 로고
    • Mice deficient in protein tyrosine phosphatase receptor type Z are resistant to gastric ulcer induction by VacA of Helicobacter pylori
    • Fujikawa A, Shirasaka D, Yamamoto S et al. Mice deficient in protein tyrosine phosphatase receptor type Z are resistant to gastric ulcer induction by VacA of Helicobacter pylori. Nat. Genet. 33(3), 375-381 (2003).
    • (2003) Nat. Genet , vol.33 , Issue.3 , pp. 375-381
    • Fujikawa, A.1    Shirasaka, D.2    Yamamoto, S.3
  • 83
    • 0033994516 scopus 로고    scopus 로고
    • Form, function, and regulation of protein tyrosine phosphatases and their involvement in human diseases
    • Li L, Dixon JE. Form, function, and regulation of protein tyrosine phosphatases and their involvement in human diseases. Semin. Immunol. 12(1), 75-84 (2000).
    • (2000) Semin. Immunol , vol.12 , Issue.1 , pp. 75-84
    • Li, L.1    Dixon, J.E.2
  • 84
    • 33745169029 scopus 로고    scopus 로고
    • Bottini N, Vang T, Cucca F, Mustelin T Role of PTPN22 in type 1 diabetes and other autoimmune diseases. Semin. Immunol. 18(4), 207-213 (2006).
    • Bottini N, Vang T, Cucca F, Mustelin T Role of PTPN22 in type 1 diabetes and other autoimmune diseases. Semin. Immunol. 18(4), 207-213 (2006).
  • 86
    • 28444469783 scopus 로고    scopus 로고
    • Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant
    • Vang T, Congia M, Macis MD et al. Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant. Nat. Genet. 37(12), 1317-1319 (2005).
    • (2005) Nat. Genet , vol.37 , Issue.12 , pp. 1317-1319
    • Vang, T.1    Congia, M.2    Macis, M.D.3
  • 87
    • 0030769147 scopus 로고    scopus 로고
    • Impaired bone marrow microenvironment and immune function in T cell protein tyrosine phosphatase-deficient mice
    • You-Ten KE, Muise ES, Itie A et al. Impaired bone marrow microenvironment and immune function in T cell protein tyrosine phosphatase-deficient mice. J. Exp. Med. 186(5), 683-693 (1997).
    • (1997) J. Exp. Med , vol.186 , Issue.5 , pp. 683-693
    • You-Ten, K.E.1    Muise, E.S.2    Itie, A.3
  • 88
    • 0037184022 scopus 로고    scopus 로고
    • Arginine methylation of STAT1 regulates its dephosphorylation by T cell protein tyrosine phosphatase
    • Zhu W, Mustelin T, David M. Arginine methylation of STAT1 regulates its dephosphorylation by T cell protein tyrosine phosphatase. J. Biol. Chem. 277(39), 35787-35790 (2002).
    • (2002) J. Biol. Chem , vol.277 , Issue.39 , pp. 35787-35790
    • Zhu, W.1    Mustelin, T.2    David, M.3
  • 89
    • 20444371557 scopus 로고    scopus 로고
    • PTPN11 mutations and genotype-phenotype correlations in Noonan and LEOPARD syndromes
    • Ogata T, Yoshida R. PTPN11 mutations and genotype-phenotype correlations in Noonan and LEOPARD syndromes. Pediatr. Endocrinol. Rev. 2(4), 669-674 (2005).
    • (2005) Pediatr. Endocrinol. Rev , vol.2 , Issue.4 , pp. 669-674
    • Ogata, T.1    Yoshida, R.2
  • 90
    • 2442648882 scopus 로고    scopus 로고
    • Mutational analysis of the tyrosine phosphatome in colorectal cancers
    • Wang Z, Shen D, Parsons DW et al. Mutational analysis of the tyrosine phosphatome in colorectal cancers. Science 304(5674), 1164-1166 (2004).
    • (2004) Science , vol.304 , Issue.5674 , pp. 1164-1166
    • Wang, Z.1    Shen, D.2    Parsons, D.W.3
  • 91
    • 33749267414 scopus 로고    scopus 로고
    • Protein tyrosine-phosphatase expression profiling in gastric cancer tissues
    • Wu CW, Kao HL, Li AF, Chi CW, Lin WC. Protein tyrosine-phosphatase expression profiling in gastric cancer tissues. Cancer Lett. 242(1), 95-103 (2006).
    • (2006) Cancer Lett , vol.242 , Issue.1 , pp. 95-103
    • Wu, C.W.1    Kao, H.L.2    Li, A.F.3    Chi, C.W.4    Lin, W.C.5
  • 92
    • 33645288620 scopus 로고    scopus 로고
    • Protein-tyrosine phosphatases and cancer
    • Ostman A, Hellberg C, Bohmer FD. Protein-tyrosine phosphatases and cancer. Nat. Rev. Cancer 6(4), 307-320 (2006).
    • (2006) Nat. Rev. Cancer , vol.6 , Issue.4 , pp. 307-320
    • Ostman, A.1    Hellberg, C.2    Bohmer, F.D.3
  • 93
    • 20444419344 scopus 로고    scopus 로고
    • Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance
    • MacKeigan JP, Murphy LO, Blenis J. Sensitized RNAi screen of human kinases and phosphatases identifies new regulators of apoptosis and chemoresistance. Nat. Cell Biol. 7(6), 591-600 (2005).
    • (2005) Nat. Cell Biol , vol.7 , Issue.6 , pp. 591-600
    • MacKeigan, J.P.1    Murphy, L.O.2    Blenis, J.3
  • 94
    • 0037242227 scopus 로고    scopus 로고
    • Hepatocyte growth factor receptor, matrix metalloproteinase-11, tissue inhibitor of metalloproteinase-1, and fibronectin are up-regulated in papillary thyroid carcinoma: A cDNA and tissue microarray study
    • Wasenius VM, Hemmer S, Kettunen E, Knuutila S, Franssila K, Joensuu H. Hepatocyte growth factor receptor, matrix metalloproteinase-11, tissue inhibitor of metalloproteinase-1, and fibronectin are up-regulated in papillary thyroid carcinoma: a cDNA and tissue microarray study. Clin. Cancer Res. 9(1), 68-75 (2003).
    • (2003) Clin. Cancer Res , vol.9 , Issue.1 , pp. 68-75
    • Wasenius, V.M.1    Hemmer, S.2    Kettunen, E.3    Knuutila, S.4    Franssila, K.5    Joensuu, H.6
  • 95
    • 0037111773 scopus 로고    scopus 로고
    • + cells from normal and myelodysplastic bone marrow. Blood 100(10), 3553-3560 (2002).
    • + cells from normal and myelodysplastic bone marrow. Blood 100(10), 3553-3560 (2002).
  • 96
    • 4444381057 scopus 로고    scopus 로고
    • A commonly deleted region in ovarian cancer on chromosome 19p l3.3, not including the OAZ1 gene
    • Yanaihara N, Okamoto A, Matsufuji S. A commonly deleted region in ovarian cancer on chromosome 19p l3.3, not including the OAZ1 gene. Int. J. Oncol. 23(3), 567-575 (2003).
    • (2003) Int. J. Oncol , vol.23 , Issue.3 , pp. 567-575
    • Yanaihara, N.1    Okamoto, A.2    Matsufuji, S.3
  • 97
    • 34547132562 scopus 로고    scopus 로고
    • Molecular gene expression signature patterns for gastric cancer diagnosis
    • Yap YL, Zhang XW, Smith D, Soong R, Hill J. Molecular gene expression signature patterns for gastric cancer diagnosis. Comput. Biol. Chem. 31(4), 275-287 (2007).
    • (2007) Comput. Biol. Chem , vol.31 , Issue.4 , pp. 275-287
    • Yap, Y.L.1    Zhang, X.W.2    Smith, D.3    Soong, R.4    Hill, J.5
  • 98
    • 13944258148 scopus 로고    scopus 로고
    • Insights into developmental mechanisms and cancers in the mammalian intestine derived from serial analysis of gene expression and study of the hepatoma-derived growth factor (HDGF)
    • Lepourcelet M, Tou L, Cai L et al. Insights into developmental mechanisms and cancers in the mammalian intestine derived from serial analysis of gene expression and study of the hepatoma-derived growth factor (HDGF). Development 132(2), 415-427(2005).
    • (2005) Development , vol.132 , Issue.2 , pp. 415-427
    • Lepourcelet, M.1    Tou, L.2    Cai, L.3
  • 99
    • 3843097204 scopus 로고    scopus 로고
    • The allelic variant of LAR gene promoter -127 bp T→A is associated with reduced risk of obesity and other features related to insulin resistance
    • Miscio G, Tassi V, Coco A et al. The allelic variant of LAR gene promoter -127 bp T→A is associated with reduced risk of obesity and other features related to insulin resistance. J. Mol. Med. 82(7), 459-466 (2004).
    • (2004) J. Mol. Med , vol.82 , Issue.7 , pp. 459-466
    • Miscio, G.1    Tassi, V.2    Coco, A.3
  • 100
    • 35549013306 scopus 로고    scopus 로고
    • Genetic variation in receptor protein tyrosine phosphatise σ is associated with type 2 diabetes in Swedish Caucasians
    • Langberg EC, Gu HF, Nordman S, Efendic S, Ostenson CG. Genetic variation in receptor protein tyrosine phosphatise σ is associated with type 2 diabetes in Swedish Caucasians. Eur. J. Endocrinol. 157(4), 459-464 (2007).
    • (2007) Eur. J. Endocrinol , vol.157 , Issue.4 , pp. 459-464
    • Langberg, E.C.1    Gu, H.F.2    Nordman, S.3    Efendic, S.4    Ostenson, C.G.5
  • 101
    • 1842866370 scopus 로고    scopus 로고
    • Association of the Pro 12Ala and C14431T variants of PPARG and their haplotypes with susceptibility to Type 2 diabetes
    • Doney AS, Fischer B, Cecil JE et al. Association of the Pro 12Ala and C14431T variants of PPARG and their haplotypes with susceptibility to Type 2 diabetes. Diabetologia 47(3), 555-558 (2004).
    • (2004) Diabetologia , vol.47 , Issue.3 , pp. 555-558
    • Doney, A.S.1    Fischer, B.2    Cecil, J.E.3
  • 102
    • 34047126320 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms of the peroxisome proliferator-activated receptor-σ gene (PPARA) influence the conversion from impaired glucose tolerance to type 2 diabetes: The STOP-NIDDM trial
    • Andrulionyte L, Kuulasmaa T, Chiasson JL, Laakso M. Single nucleotide polymorphisms of the peroxisome proliferator-activated receptor-σ gene (PPARA) influence the conversion from impaired glucose tolerance to type 2 diabetes: the STOP-NIDDM trial. Diabetes 56(4), 1181-1186(2007).
    • (2007) Diabetes , vol.56 , Issue.4 , pp. 1181-1186
    • Andrulionyte, L.1    Kuulasmaa, T.2    Chiasson, J.L.3    Laakso, M.4
  • 103
    • 14944361781 scopus 로고    scopus 로고
    • Linkage to peroxisome proliferator-activated receptor-gamma in SAMP1/YitFc mice and in human Crohn's disease
    • Sugawara K, Olson TS, Moskaluk CA et al. Linkage to peroxisome proliferator-activated receptor-gamma in SAMP1/YitFc mice and in human Crohn's disease. Gastroenterology 128(2), 351-360(2005).
    • (2005) Gastroenterology , vol.128 , Issue.2 , pp. 351-360
    • Sugawara, K.1    Olson, T.S.2    Moskaluk, C.A.3
  • 104
    • 0027257623 scopus 로고
    • Cloning and expression of two structurally distinct receptor-linked protein-tyrosine phosphatases generated by RNA processing from a single gene
    • Pan MG, Rim C, Lu KP, Florio T, Stork PJ. Cloning and expression of two structurally distinct receptor-linked protein-tyrosine phosphatases generated by RNA processing from a single gene. J Biol. Chem. 268(26), 19284-19291 (1993).
    • (1993) J Biol. Chem , vol.268 , Issue.26 , pp. 19284-19291
    • Pan, M.G.1    Rim, C.2    Lu, K.P.3    Florio, T.4    Stork, P.J.5
  • 105
    • 0027237605 scopus 로고
    • A novel receptor-type protein tyrosine phosphatase is expressed during neurogenesis in the olfactory neuroepithelium
    • Walton KM, Martell KJ, Kwak SP, Dixon JE, Largent BL. A novel receptor-type protein tyrosine phosphatase is expressed during neurogenesis in the olfactory neuroepithelium. Neuron 11 (2), 387-400(1993).
    • (1993) Neuron , vol.11 , Issue.2 , pp. 387-400
    • Walton, K.M.1    Martell, K.J.2    Kwak, S.P.3    Dixon, J.E.4    Largent, B.L.5
  • 106
    • 0027428775 scopus 로고
    • A novel receptor tyrosine phosphatase-σ that is highly expressed in the nervous system
    • Yan H, Grossman A, Wang H et al. A novel receptor tyrosine phosphatase-σ that is highly expressed in the nervous system. J Biol. Chem. 268(33), 24880-24886 (1993).
    • (1993) J Biol. Chem , vol.268 , Issue.33 , pp. 24880-24886
    • Yan, H.1    Grossman, A.2    Wang, H.3
  • 107
    • 0028363184 scopus 로고
    • Isoforms of a novel cell adhesion molecule-like protein tyrosine phosphatase are implicated in neural development
    • Stoker AW. Isoforms of a novel cell adhesion molecule-like protein tyrosine phosphatase are implicated in neural development. Mech. Dev. 46(3), 201-217 (1994).
    • (1994) Mech. Dev , vol.46 , Issue.3 , pp. 201-217
    • Stoker, A.W.1
  • 108
    • 0028566661 scopus 로고
    • Molecular cloning and tissue-specific RNA processing of a murine receptor-type protein tyrosine phosphatase
    • Wagner J, Boerboom D, Tremblay ML. Molecular cloning and tissue-specific RNA processing of a murine receptor-type protein tyrosine phosphatase. Eur. J. Biochem. 226(3), 773-782(1994).
    • (1994) Eur. J. Biochem , vol.226 , Issue.3 , pp. 773-782
    • Wagner, J.1    Boerboom, D.2    Tremblay, M.L.3
  • 109
    • 0028000709 scopus 로고
    • Molecular cloning and expression of a unique receptor-like protein-tyrosine-phosphatase in the leucocyte-common-antigen-related phosphate family
    • Zhang WR, Hashimoto N, Ahmad F, Ding W, Goldstein BJ. Molecular cloning and expression of a unique receptor-like protein-tyrosine-phosphatase in the leucocyte-common-antigen-related phosphate family. Biochem. J. 302(Pt 1), 39-47(1994).
    • (1994) Biochem. J , vol.302 , Issue.PART 1 , pp. 39-47
    • Zhang, W.R.1    Hashimoto, N.2    Ahmad, F.3    Ding, W.4    Goldstein, B.J.5
  • 110
    • 0028861680 scopus 로고
    • Seven protein tyrosine phosphatases are differentially expressed in the developing rat brain
    • SahinM, DowlingJJ, Hockfield S. Seven protein tyrosine phosphatases are differentially expressed in the developing rat brain. J Comp. Neurol. 351(4), 617-631 (1995).
    • (1995) J Comp. Neurol , vol.351 , Issue.4 , pp. 617-631
    • Sahin, M.1    Dowling, J.J.2    Hockfield, S.3
  • 111
    • 0024211451 scopus 로고
    • A new member of the immunoglobulin superfamily that has a cytoplasmic region homologous to the leukocyte common antigen
    • Streuli M, Krueger NX, Hall LR, Schlossman SF, Saito H. A new member of the immunoglobulin superfamily that has a cytoplasmic region homologous to the leukocyte common antigen. J Exp. Med. 168(5), 1523-1530(1988).
    • (1988) J Exp. Med , vol.168 , Issue.5 , pp. 1523-1530
    • Streuli, M.1    Krueger, N.X.2    Hall, L.R.3    Schlossman, S.F.4    Saito, H.5
  • 112
    • 0025146562 scopus 로고
    • Structural diversity and evolution of human receptorlike protein tyrosine phosphatases
    • Krueger NX, Streuli M, Saito H. Structural diversity and evolution of human receptorlike protein tyrosine phosphatases. EMBO J. 9(10), 3241-3252 (1990).
    • (1990) EMBO J , vol.9 , Issue.10 , pp. 3241-3252
    • Krueger, N.X.1    Streuli, M.2    Saito, H.3
  • 113
    • 0027237709 scopus 로고
    • MPTP δ, a putative murine homolog of HPTP Δ, is expressed in specialized regions of the brain and in the B-cell lineage
    • Mizuno K, Hasegawa K, Katagiri T, Ogimoto M, Ichikawa T, Yakura H. MPTP δ, a putative murine homolog of HPTP Δ, is expressed in specialized regions of the brain and in the B-cell lineage. Mol. Cell Biol. 13(9), 5513-5523(1993).
    • (1993) Mol. Cell Biol , vol.13 , Issue.9 , pp. 5513-5523
    • Mizuno, K.1    Hasegawa, K.2    Katagiri, T.3    Ogimoto, M.4    Ichikawa, T.5    Yakura, H.6
  • 114
    • 0026583744 scopus 로고
    • Expression of the receptor-linked protein tyrosine phosphatase LAR: Proteolytic cleavage and shedding of the CAM-like extracellular region
    • Streuli M, Krueger NX, Ariniello PD et al. Expression of the receptor-linked protein tyrosine phosphatase LAR: proteolytic cleavage and shedding of the CAM-like extracellular region. EMBO J. 11 (3), 897-907(1992).
    • (1992) EMBO J , vol.11 , Issue.3 , pp. 897-907
    • Streuli, M.1    Krueger, N.X.2    Ariniello, P.D.3
  • 115
    • 0027984009 scopus 로고
    • Genomic organization of the human LAR protein tyrosine phosphatase gene and alternative splicing in the extracellular fibronectin type-Ill domains
    • O'Grady P, Krueger NX, Streuli M, Saito H. Genomic organization of the human LAR protein tyrosine phosphatase gene and alternative splicing in the extracellular fibronectin type-Ill domains. J Biol. Chem. 269(40), 25193-25199 (1994).
    • (1994) J Biol. Chem , vol.269 , Issue.40 , pp. 25193-25199
    • O'Grady, P.1    Krueger, N.X.2    Streuli, M.3    Saito, H.4
  • 116
    • 0027992048 scopus 로고
    • Mutational analysis of proprotein processing, subunit association, and shedding of the LAR transmembrane protein tyrosine phosphatase
    • Serra-Pages C, Saito H, Streuli M. Mutational analysis of proprotein processing, subunit association, and shedding of the LAR transmembrane protein tyrosine phosphatase. J Biol. Chem. 269(38), 23632-23641 (1994).
    • (1994) J Biol. Chem , vol.269 , Issue.38 , pp. 23632-23641
    • Serra-Pages, C.1    Saito, H.2    Streuli, M.3
  • 117
    • 0028926584 scopus 로고
    • LAR tyrosine phosphatase receptor: Alternative splicing is preferential to the nervous system, coordinated with cell growth and generates novel isoforms containing extensive CAG repeats
    • Zhang JS, Longo FM. LAR tyrosine phosphatase receptor: alternative splicing is preferential to the nervous system, coordinated with cell growth and generates novel isoforms containing extensive CAG repeats. J Cell Biol. 128(3), 415-431 (1995).
    • (1995) J Cell Biol , vol.128 , Issue.3 , pp. 415-431
    • Zhang, J.S.1    Longo, F.M.2
  • 118
    • 0028156386 scopus 로고
    • Expression of the tyrosine phosphatase LAR-PTP2 is developmentally regulated in lung epithelia
    • Rotin D, Goldstein BJ, Fladd CA. Expression of the tyrosine phosphatase LAR-PTP2 is developmentally regulated in lung epithelia. Am. J. Physiol. 267(3 Pt 1), L263-L270 (1994).
    • (1994) Am. J. Physiol , vol.267 , Issue.3 PART 1
    • Rotin, D.1    Goldstein, B.J.2    Fladd, C.A.3
  • 119
    • 0036180772 scopus 로고    scopus 로고
    • Heparan sulfate proteoglycans are ligands for receptor protein tyrosine phosphatase σ
    • Aricescu AR, McKinnell IW, Halfter W, Stoker AW. Heparan sulfate proteoglycans are ligands for receptor protein tyrosine phosphatase σ. Mol. Cell Biol. 22(6), 1881-1892(2002).
    • (2002) Mol. Cell Biol , vol.22 , Issue.6 , pp. 1881-1892
    • Aricescu, A.R.1    McKinnell, I.W.2    Halfter, W.3    Stoker, A.W.4
  • 120
    • 0037282713 scopus 로고    scopus 로고
    • Isoform-specific binding of the tyrosine phosphatase PTPσ to a ligand in developing muscle
    • Sajnani-Perez G, Chilton JK, Aricescu AR, Haj F, Stoker AW. Isoform-specific binding of the tyrosine phosphatase PTPσ to a ligand in developing muscle. Mol. Cell Neurosci. 22(1), 37-48 (2003).
    • (2003) Mol. Cell Neurosci , vol.22 , Issue.1 , pp. 37-48
    • Sajnani-Perez, G.1    Chilton, J.K.2    Aricescu, A.R.3    Haj, F.4    Stoker, A.W.5
  • 121
    • 33749387684 scopus 로고    scopus 로고
    • Cell surface nucleolin on developing muscle is a potential ligand for the axonal receptor protein tyrosine phosphatase-σ
    • Alete DE, Weeks ME, Hovanession AG, Hawadle M, Stoker AW. Cell surface nucleolin on developing muscle is a potential ligand for the axonal receptor protein tyrosine phosphatase-σ. FEBS J. 273(20), 4668-4681 (2006).
    • (2006) FEBS J , vol.273 , Issue.20 , pp. 4668-4681
    • Alete, D.E.1    Weeks, M.E.2    Hovanession, A.G.3    Hawadle, M.4    Stoker, A.W.5
  • 122
    • 33847206745 scopus 로고    scopus 로고
    • Dimerization of ptpσ governs both ligand binding and isoform specificity
    • Lee S, Faux C, Nixon J et al. Dimerization of ptpσ governs both ligand binding and isoform specificity. Mol. Cell Biol. 27(5), 1795-1808 (2007).
    • (2007) Mol. Cell Biol , vol.27 , Issue.5 , pp. 1795-1808
    • Lee, S.1    Faux, C.2    Nixon, J.3
  • 123
    • 0030953448 scopus 로고    scopus 로고
    • Protein tyrosine phosphatases in signal transduction
    • Neel BG, Tonks NK. Protein tyrosine phosphatases in signal transduction. Curr. Opin. Cell Biol. 9(2), 193-204 (1997).
    • (1997) Curr. Opin. Cell Biol , vol.9 , Issue.2 , pp. 193-204
    • Neel, B.G.1    Tonks, N.K.2
  • 124
    • 0033858043 scopus 로고    scopus 로고
    • Emerging issues in receptor protein tyrosine phosphatase function: Lifting fog or simply shifting?
    • Petrone A, Sap J. Emerging issues in receptor protein tyrosine phosphatase function: lifting fog or simply shifting? J. Cell Sci. 113(Pt 13), 2345-2354 (2000).
    • (2000) J. Cell Sci , vol.113 , Issue.PART 13 , pp. 2345-2354
    • Petrone, A.1    Sap, J.2
  • 125
    • 0037207476 scopus 로고    scopus 로고
    • Receptor protein tyrosine phosphatases in nervous system development
    • Johnson KG, Van Vactor D. Receptor protein tyrosine phosphatases in nervous system development. Physiol. Rev. 83(1), 1-24 (2003).
    • (2003) Physiol. Rev , vol.83 , Issue.1 , pp. 1-24
    • Johnson, K.G.1    Van Vactor, D.2
  • 126
    • 0033082439 scopus 로고    scopus 로고
    • The tyrosine kinase Abl and its substrate enabled collaborate with the receptor phosphatase Dlar to control motor axon guidance
    • Wills Z, Bateman J, Korey CA, Comer A, Van Vactor D. The tyrosine kinase Abl and its substrate enabled collaborate with the receptor phosphatase Dlar to control motor axon guidance. Neuron 22(2), 301-312 (1999).
    • (1999) Neuron , vol.22 , Issue.2 , pp. 301-312
    • Wills, Z.1    Bateman, J.2    Korey, C.A.3    Comer, A.4    Van Vactor, D.5
  • 127
    • 0032546658 scopus 로고    scopus 로고
    • Serra-Pages C, Medley QG, Tang M, Hart A, Streuli M. Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins. J. Biol. Chem. 273(25), 15611-15620 (1998).
    • Serra-Pages C, Medley QG, Tang M, Hart A, Streuli M. Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins. J. Biol. Chem. 273(25), 15611-15620 (1998).
  • 128
    • 0029019297 scopus 로고
    • The LAR transmembrane protein tyrosine phosphatase and a coiled-coil LAR-interacting protein co-localize at focal adhesions
    • Serra-Pages C, Kedersha NL, Fazikas L, Medley Q, Debant A, Streuli M. The LAR transmembrane protein tyrosine phosphatase and a coiled-coil LAR-interacting protein co-localize at focal adhesions. EMBO J. 14(12), 2827-2838 (1995).
    • (1995) EMBO J , vol.14 , Issue.12 , pp. 2827-2838
    • Serra-Pages, C.1    Kedersha, N.L.2    Fazikas, L.3    Medley, Q.4    Debant, A.5    Streuli, M.6
  • 129
    • 0029417204 scopus 로고
    • The LAR/PTPδ/PTPσ subfamily of transmembrane protein-tyrosine -phosphatases: Multiple human LAR, PTPδ, and PTPδ isoforms are expressed in a tissue- specific manner and associate with the LAR-interacting protein LIP.1
    • Pulido R, Serra-Pages C, Tang M, Streuli M. The LAR/PTPδ/PTPσ subfamily of transmembrane protein-tyrosine -phosphatases: multiple human LAR, PTPδ, and PTPδ isoforms are expressed in a tissue- specific manner and associate with the LAR-interacting protein LIP.1. Proc. Natl Acad. Sci. USA 92(25), 11686-11690 (1995).
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , Issue.25 , pp. 11686-11690
    • Pulido, R.1    Serra-Pages, C.2    Tang, M.3    Streuli, M.4
  • 130
    • 0029952315 scopus 로고    scopus 로고
    • The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains
    • Debant A, Serra-Pages C, Seipel K et al. The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains. Proc. Natl Acad. Sci. USA 93(11), 5466-5471 (1996).
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , Issue.11 , pp. 5466-5471
    • Debant, A.1    Serra-Pages, C.2    Seipel, K.3
  • 131
    • 0032523935 scopus 로고    scopus 로고
    • clr-1 encodes a receptor tyrosine phosphatase that negatively regulates an FGF receptor signaling pathway in Caenorhabditis elegans
    • Kokel M, Borland CZ, DeLong L, Horvitz HR, Stern MJ. clr-1 encodes a receptor tyrosine phosphatase that negatively regulates an FGF receptor signaling pathway in Caenorhabditis elegans. Genes Dev. 12(10), 1425-1437 (1998).
    • (1998) Genes Dev , vol.12 , Issue.10 , pp. 1425-1437
    • Kokel, M.1    Borland, C.Z.2    DeLong, L.3    Horvitz, H.R.4    Stern, M.J.5
  • 132
    • 35548930637 scopus 로고    scopus 로고
    • PTPo binds and dephosphorylates neurotrophin receptors and can suppress NGF-dependent neurite outgrowth from sensory neurons
    • Faux C, Hawadle M, Nixon J et al. PTPo binds and dephosphorylates neurotrophin receptors and can suppress NGF-dependent neurite outgrowth from sensory neurons. Biochim. Biophys. Acta 1773(11), 1689-1700 (2007).
    • (2007) Biochim. Biophys. Acta , vol.1773 , Issue.11 , pp. 1689-1700
    • Faux, C.1    Hawadle, M.2    Nixon, J.3
  • 133
    • 33845763350 scopus 로고    scopus 로고
    • N-cadherin is an in vivo substrate for protein tyrosine phosphatase σ (PTPσ) and participates in PTPσ-mediated inhibition of axon growth
    • Siu R, Fladd C, Rotin D. N-cadherin is an in vivo substrate for protein tyrosine phosphatase σ (PTPσ) and participates in PTPσ-mediated inhibition of axon growth. Mol. Cell Biol. 27(1), 208-219 (2007).
    • (2007) Mol. Cell Biol , vol.27 , Issue.1 , pp. 208-219
    • Siu, R.1    Fladd, C.2    Rotin, D.3
  • 134
    • 0033051169 scopus 로고    scopus 로고
    • Neuronal defects and posterior pituitary hypoplasia in mice lacking the receptor tyrosine phosphatase PTPσ
    • Wallace MJ, Batt J, Fladd CA, Henderson JT, Skarnes W, Rotin D. Neuronal defects and posterior pituitary hypoplasia in mice lacking the receptor tyrosine phosphatase PTPσ. Nat. Genet. 21(3), 334-338 (1999).
    • (1999) Nat. Genet , vol.21 , Issue.3 , pp. 334-338
    • Wallace, M.J.1    Batt, J.2    Fladd, C.A.3    Henderson, J.T.4    Skarnes, W.5    Rotin, D.6
  • 135
    • 0032979722 scopus 로고    scopus 로고
    • Neuroendocrine dysplasia in mice lacking protein tyrosine phosphatase σ
    • Elchebly M, Wagner J, Kennedy TE et al. Neuroendocrine dysplasia in mice lacking protein tyrosine phosphatase σ. Nat. Genet. 21(3), 330-333(1999).
    • (1999) Nat. Genet , vol.21 , Issue.3 , pp. 330-333
    • Elchebly, M.1    Wagner, J.2    Kennedy, T.E.3
  • 136
    • 0036137813 scopus 로고    scopus 로고
    • Pituitary, pancreatic and gut neuroendocrine defects in protein tyrosine phosphatase-σ-deficient mice
    • Batt J, Asa S, Fladd C, Rotin D. Pituitary, pancreatic and gut neuroendocrine defects in protein tyrosine phosphatase-σ-deficient mice. Mol. Endocrinol. 16(1), 155-169 (2002).
    • (2002) Mol. Endocrinol , vol.16 , Issue.1 , pp. 155-169
    • Batt, J.1    Asa, S.2    Fladd, C.3    Rotin, D.4
  • 137
    • 0030588587 scopus 로고    scopus 로고
    • Physical mapping of receptor type protein tyrosine phosphatase σ (PTPRS) to human chromosome 19pl3.3
    • Wagner J, Gordon LA, Heng HH, Tremblay ML, Olsen AS. Physical mapping of receptor type protein tyrosine phosphatase σ (PTPRS) to human chromosome 19pl3.3. Genomics 38(1), 76-78 (1996).
    • (1996) Genomics , vol.38 , Issue.1 , pp. 76-78
    • Wagner, J.1    Gordon, L.A.2    Heng, H.H.3    Tremblay, M.L.4    Olsen, A.S.5
  • 138
    • 0033910870 scopus 로고    scopus 로고
    • Genomewide search in Canadian families with inflammatory bowel disease reveals two novel susceptibility loci
    • Rioux JD, Silverberg MS, Daly MJ et al. Genomewide search in Canadian families with inflammatory bowel disease reveals two novel susceptibility loci. Am. J. Hum. Genet. 66(6), 1863-1870 (2000).
    • (2000) Am. J. Hum. Genet , vol.66 , Issue.6 , pp. 1863-1870
    • Rioux, J.D.1    Silverberg, M.S.2    Daly, M.J.3
  • 139
    • 79959503826 scopus 로고    scopus 로고
    • The International HapMap Project
    • The International HapMap Project. Nature 426(6968), 789-796 (2003).
    • (2003) Nature , vol.426 , Issue.6968 , pp. 789-796
  • 140
    • 34347335667 scopus 로고    scopus 로고
    • Guilt beyond a reasonable doubt
    • Altshuler D, Daly M. Guilt beyond a reasonable doubt. Nat. Genet. 39(7), 813-815 (2007).
    • (2007) Nat. Genet , vol.39 , Issue.7 , pp. 813-815
    • Altshuler, D.1    Daly, M.2
  • 141
    • 0029873660 scopus 로고    scopus 로고
    • Human protein tyrosine phosphatase-σ: Alternative splicing and inhibition by bisphosphonates
    • Endo N, Rutledge SJ, Opas EE, Vogel R, Rodan GA, Schmidt A. Human protein tyrosine phosphatase-σ: alternative splicing and inhibition by bisphosphonates. J. Bone Miner. Res. 11(4), 535-543 (1996).
    • (1996) J. Bone Miner. Res , vol.11 , Issue.4 , pp. 535-543
    • Endo, N.1    Rutledge, S.J.2    Opas, E.E.3    Vogel, R.4    Rodan, G.A.5    Schmidt, A.6
  • 142
    • 33746552163 scopus 로고    scopus 로고
    • Splice variant 3, but not 2 of receptor protein-tyrosine phosphatase σ can mediate stimulation of insulin-secretion by α-latrotoxin
    • Lajus S, Lang J. Splice variant 3, but not 2 of receptor protein-tyrosine phosphatase σ can mediate stimulation of insulin-secretion by α-latrotoxin. J. Cell Biochem. 98(6), 1552-5159(2006).
    • (2006) J. Cell Biochem , vol.98 , Issue.6 , pp. 1552-5159
    • Lajus, S.1    Lang, J.2
  • 143
    • 33748329408 scopus 로고    scopus 로고
    • Review article: The role of bacteria in onset and perpetuation of inflammatory bowel disease
    • Seksik P, Sokol H, Lepage P et al. Review article: the role of bacteria in onset and perpetuation of inflammatory bowel disease. Aliment. Pharmacol. Ther. 24(Suppl. 3), 11-18 (2006).
    • (2006) Aliment. Pharmacol. Ther , vol.24 , Issue.SUPPL. 3 , pp. 11-18
    • Seksik, P.1    Sokol, H.2    Lepage, P.3
  • 144
    • 13844320540 scopus 로고    scopus 로고
    • Apoptosis or necrosis - colonic epithelial cell survival
    • discussion 45-50, 211-218
    • Gibson PR. Apoptosis or necrosis - colonic epithelial cell survival. Novartis Found. Symp. 263, 133-145; discussion 45-50, 211-218 (2004).
    • (2004) Novartis Found. Symp , vol.263 , pp. 133-145
    • Gibson, P.R.1
  • 145
    • 5644288503 scopus 로고    scopus 로고
    • Early loss of E-cadherin from cell - cell contacts is involved in the onset of Anoikis in enterocytes
    • Fouquet S, Lugo-Martinez VH, Faussat AM et al. Early loss of E-cadherin from cell - cell contacts is involved in the onset of Anoikis in enterocytes. J. Biol. Chem. 279(41), 43061-43069 (2004).
    • (2004) J. Biol. Chem , vol.279 , Issue.41 , pp. 43061-43069
    • Fouquet, S.1    Lugo-Martinez, V.H.2    Faussat, A.M.3
  • 146
    • 24644447079 scopus 로고    scopus 로고
    • The regulation of cadherin-mediated adhesion by tyrosine phosphorylation/dephosphorylation of β-catenin
    • Lilien J, Balsamo J. The regulation of cadherin-mediated adhesion by tyrosine phosphorylation/dephosphorylation of β-catenin. Curr. Opin. Cell Biol. 17(5), 459-465 (2005).
    • (2005) Curr. Opin. Cell Biol , vol.17 , Issue.5 , pp. 459-465
    • Lilien, J.1    Balsamo, J.2
  • 147
    • 0031259778 scopus 로고    scopus 로고
    • Tyrosine phosphorylation and cadherin/catenin function
    • Daniel JM, Reynolds AB. Tyrosine phosphorylation and cadherin/catenin function. Bioessays 19(10), 883-891 (1997).
    • (1997) Bioessays , vol.19 , Issue.10 , pp. 883-891
    • Daniel, J.M.1    Reynolds, A.B.2
  • 148
    • 0026742310 scopus 로고
    • Cadherin-mediated cell-cell adhesion is perturbed by v-src tyrosine phosphorylation in metastatic fibroblasts
    • Matsuyoshi N, Hamaguchi M, Taniguchi S, Nagafuchi A, Tsukita S, Takeichi M. Cadherin-mediated cell-cell adhesion is perturbed by v-src tyrosine phosphorylation in metastatic fibroblasts. J. Cell Biol. 118(3), 703-714 (1992).
    • (1992) J. Cell Biol , vol.118 , Issue.3 , pp. 703-714
    • Matsuyoshi, N.1    Hamaguchi, M.2    Taniguchi, S.3    Nagafuchi, A.4    Tsukita, S.5    Takeichi, M.6
  • 149
    • 0027459346 scopus 로고
    • p60v-src causes tyrosine phosphorylation and inactivation of the N-cadherin-catenin cell adhesion system
    • Hamaguchi M, Matsuyoshi N, Ohnishi Y, Gotoh B, Takeichi M, Nagai Y. p60v-src causes tyrosine phosphorylation and inactivation of the N-cadherin-catenin cell adhesion system. EMBO J. 12(1), 307-314 (1993).
    • (1993) EMBO J , vol.12 , Issue.1 , pp. 307-314
    • Hamaguchi, M.1    Matsuyoshi, N.2    Ohnishi, Y.3    Gotoh, B.4    Takeichi, M.5    Nagai, Y.6
  • 150
    • 0026529501 scopus 로고
    • The effect of tyrosine-specific protein phosphorylation on the assembly of adherens-type junctions
    • Volberg T, Zick Y, Dror R et al. The effect of tyrosine-specific protein phosphorylation on the assembly of adherens-type junctions. EMBO J. 11(5), 1733-1742 (1992).
    • (1992) EMBO J , vol.11 , Issue.5 , pp. 1733-1742
    • Volberg, T.1    Zick, Y.2    Dror, R.3
  • 151
    • 0032489681 scopus 로고    scopus 로고
    • Dynamic interaction of PTPmu with multiple cadherins in vitro
    • Brady-Kalnay SM, Mourton T, Nixon JP et al. Dynamic interaction of PTPmu with multiple cadherins in vitro. J. Cell Biol. 141(1), 287-296 (1998).
    • (1998) J. Cell Biol , vol.141 , Issue.1 , pp. 287-296
    • Brady-Kalnay, S.M.1    Mourton, T.2    Nixon, J.P.3
  • 152
    • 0030836799 scopus 로고    scopus 로고
    • Cellular redistribution of protein tyrosine phosphatases LAR and PTPσ by inducible proteolytic processing
    • Aicher B, Lerch MM, Muller T, Schilling J, Ullrich A. Cellular redistribution of protein tyrosine phosphatases LAR and PTPσ by inducible proteolytic processing. J. Cell Biol. 138(3), 681-696 (1997).
    • (1997) J. Cell Biol , vol.138 , Issue.3 , pp. 681-696
    • Aicher, B.1    Lerch, M.M.2    Muller, T.3    Schilling, J.4    Ullrich, A.5
  • 153
    • 0034785352 scopus 로고    scopus 로고
    • Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease
    • Rioux JD, Daly MJ, Silverberg MS et al. Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease. Nat. Genet. 29(2), 223-228 (2001).
    • (2001) Nat. Genet , vol.29 , Issue.2 , pp. 223-228
    • Rioux, J.D.1    Daly, M.J.2    Silverberg, M.S.3
  • 154
    • 33746572328 scopus 로고    scopus 로고
    • Fine mapping and positional candidate studies on chromosome 5p 13 identify multiple asthma susceptibility loci
    • Kurz T, Hoffjan S, Hayes MG et al. Fine mapping and positional candidate studies on chromosome 5p 13 identify multiple asthma susceptibility loci. J. Allergy Clin. Immunol. 118(2), 396-402 (2006).
    • (2006) J. Allergy Clin. Immunol , vol.118 , Issue.2 , pp. 396-402
    • Kurz, T.1    Hoffjan, S.2    Hayes, M.G.3
  • 155
    • 42449153256 scopus 로고    scopus 로고
    • Two-stage candidate gene study of chromosome 3p demonstrates an association between nonsynonymous variants in the MST1R gene and Crohn's disease
    • BecklyJB, Hancock L, GeremiaA et al. Two-stage candidate gene study of chromosome 3p demonstrates an association between nonsynonymous variants in the MST1R gene and Crohn's disease. Inflamm. Bowel Dis. (2008).
    • (2008) Inflamm. Bowel Dis
    • Beckly, J.B.1    Hancock, L.2    Geremia, A.3
  • 156
    • 34547459989 scopus 로고    scopus 로고
    • The role of the Toll receptor pathway in susceptibility to inflammatory bowel diseases
    • De Jager PL, Franchimont D, Waliszewska A et al. The role of the Toll receptor pathway in susceptibility to inflammatory bowel diseases. Genes Immun. 8(5), 387-397 (2007).
    • (2007) Genes Immun , vol.8 , Issue.5 , pp. 387-397
    • De Jager, P.L.1    Franchimont, D.2    Waliszewska, A.3
  • 157
    • 20244373335 scopus 로고    scopus 로고
    • NOD2/CARD15 and TNFA, but not IL1B and IL1RN, are associated with Crohn's disease
    • Ferreira AC, Almeida S, Tavares M et al. NOD2/CARD15 and TNFA, but not IL1B and IL1RN, are associated with Crohn's disease. Inflamm. Bowel Dis. 11(4), 331-339(2005).
    • (2005) Inflamm. Bowel Dis , vol.11 , Issue.4 , pp. 331-339
    • Ferreira, A.C.1    Almeida, S.2    Tavares, M.3
  • 158
    • 0347917295 scopus 로고    scopus 로고
    • Functional annotation of a novel NFKB1 promoter polymorphism that increases risk for ulcerative colitis
    • Karban AS, Okazaki T, Panhuysen CI et al. Functional annotation of a novel NFKB1 promoter polymorphism that increases risk for ulcerative colitis. Hum. Mol Genet. 13(1), 35-45 (2004).
    • (2004) Hum. Mol Genet , vol.13 , Issue.1 , pp. 35-45
    • Karban, A.S.1    Okazaki, T.2    Panhuysen, C.I.3
  • 160
    • 38149075439 scopus 로고    scopus 로고
    • Angiotensinogen and transforming growth factor β1: Novel genes in the pathogenesis of Crohn's disease
    • Hume GE, Fowler EV, Lincoln D et al. Angiotensinogen and transforming growth factor β1: novel genes in the pathogenesis of Crohn's disease. J. Med. Genet. 43(10), E51 (2006).
    • (2006) J. Med. Genet , vol.43 , Issue.10
    • Hume, G.E.1    Fowler, E.V.2    Lincoln, D.3
  • 161
    • 34548120895 scopus 로고    scopus 로고
    • Association of BclI polymorphism of the glucocorticoid receptor gene locus with response to glucocorticoids in inflammatory bowel disease
    • De Iudicibus S, Stocco G, Martelossi S et al. Association of BclI polymorphism of the glucocorticoid receptor gene locus with response to glucocorticoids in inflammatory bowel disease. Gut 56(9), 1319-1320(2007).
    • (2007) Gut , vol.56 , Issue.9 , pp. 1319-1320
    • De Iudicibus, S.1    Stocco, G.2    Martelossi, S.3
  • 162
    • 33845981518 scopus 로고    scopus 로고
    • Association of the macrophage migration inhibitory factor gene polymorphisms with inflammatory bowel disease
    • Oliver J, Marquez A, Gomez-Garcia M et al. Association of the macrophage migration inhibitory factor gene polymorphisms with inflammatory bowel disease. Gut 56(l), 150-151 (2007).
    • (2007) Gut , vol.56 , Issue.L , pp. 150-151
    • Oliver, J.1    Marquez, A.2    Gomez-Garcia, M.3
  • 163
    • 19744366535 scopus 로고    scopus 로고
    • Association between a complex insertion/deletion polymorphism in NODI (CARD4) and susceptibility to inflammatory bowel disease
    • McGovern DP, Hysi P, Ahmad T et al. Association between a complex insertion/deletion polymorphism in NODI (CARD4) and susceptibility to inflammatory bowel disease. Hum. Mol. Genet. 14(10), 1245-1250 (2005).
    • (2005) Hum. Mol. Genet , vol.14 , Issue.10 , pp. 1245-1250
    • McGovern, D.P.1    Hysi, P.2    Ahmad, T.3
  • 164
    • 33749465291 scopus 로고    scopus 로고
    • TUCAN (CARD8) genetic variants and inflammatory bowel disease
    • McGovern DP, Butler H, Ahmad T et al. TUCAN (CARD8) genetic variants and inflammatory bowel disease. Gastroenterology 131(4), 1190-1196 (2006).
    • (2006) Gastroenterology , vol.131 , Issue.4 , pp. 1190-1196
    • McGovern, D.P.1    Butler, H.2    Ahmad, T.3
  • 165
    • 0028986724 scopus 로고
    • HIA-DRB1*1502 allele, subtype of DR15, is associated with susceptibility to ulcerative colitis and its progression
    • Futami S, Aoyama N, Honsako Y et al. HIA-DRB1*1502 allele, subtype of DR15, is associated with susceptibility to ulcerative colitis and its progression. Dig. Dis. Sci. 40(4), 814-818 (1995).
    • (1995) Dig. Dis. Sci , vol.40 , Issue.4 , pp. 814-818
    • Futami, S.1    Aoyama, N.2    Honsako, Y.3
  • 166
    • 34447094130 scopus 로고    scopus 로고
    • Butyrophilin-like 2 gene is associated with ulcerative colitis in the Japanese under strong linkage disequilibrium with HLA-DRB 1*1502
    • Mochida A, Kinouchi Y, Negoro K et al. Butyrophilin-like 2 gene is associated with ulcerative colitis in the Japanese under strong linkage disequilibrium with HLA-DRB 1*1502. Tissue Antigens 70(2), 128-135 (2007).
    • (2007) Tissue Antigens , vol.70 , Issue.2 , pp. 128-135
    • Mochida, A.1    Kinouchi, Y.2    Negoro, K.3
  • 167
    • 38149114618 scopus 로고    scopus 로고
    • The influence of polymorphisms of interleukin-17a and interleukin-17f genes on the susceptibility to ulcerative colitis
    • Arisawa T, Tahara T, Shibata T et al. The influence of polymorphisms of interleukin-17a and interleukin-17f genes on the susceptibility to ulcerative colitis. J Clin. Immunol. 28(1), 44-49 (2008).
    • (2008) J Clin. Immunol , vol.28 , Issue.1 , pp. 44-49
    • Arisawa, T.1    Tahara, T.2    Shibata, T.3
  • 168
    • 0036528325 scopus 로고    scopus 로고
    • Interleukin (IL)-l β, IL-1 receptor antagonist and IL-4 gene polymorphisms in ulcerative colitis in the Chinese]
    • Peng Z, Hu P, Cui Y, Li C. [Interleukin (IL)-l β, IL-1 receptor antagonist and IL-4 gene polymorphisms in ulcerative colitis in the Chinese]. Zhonghua Nei Ke Za Zhi 41(4), 248-251 (2002).
    • (2002) Zhonghua Nei Ke Za Zhi , vol.41 , Issue.4 , pp. 248-251
    • Peng, Z.1    Hu, P.2    Cui, Y.3    Li, C.4
  • 169
    • 19044398915 scopus 로고    scopus 로고
    • A polymorphism in the IL11 gene is associated with ulcerative colitis
    • Klein W, Tromm A, Griga T et al. A polymorphism in the IL11 gene is associated with ulcerative colitis. Genes Immun. 3(8), 494-496 (2002).
    • (2002) Genes Immun , vol.3 , Issue.8 , pp. 494-496
    • Klein, W.1    Tromm, A.2    Griga, T.3
  • 170
    • 0035990180 scopus 로고    scopus 로고
    • Ulcerative colitis is associated with a promoter polymorphism of lipopolysaccharide receptor gene, CD14
    • Obana N, Takahashi S, Kinouchi Y et al. Ulcerative colitis is associated with a promoter polymorphism of lipopolysaccharide receptor gene, CD14. Scand. J. Gastroenterol. 37(6), 699-704 (2002).
    • (2002) Scand. J. Gastroenterol , vol.37 , Issue.6 , pp. 699-704
    • Obana, N.1    Takahashi, S.2    Kinouchi, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.