Genetic variation in receptor protein tyrosine phosphatase σ is associated with type 2 diabetes in Swedish Caucasians

European Journal of Endocrinology

Volumn 157, Issue 4, 2007, Pages 459-464

  Långberg, Ewa Carin ^a   Gu, Harvest F ^a   Nordman, Sofia ^a   Efendic, Suad ^a   Östenson, Claes Göran ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN TYROSINE PHOSPHATASE; RECEPTOR PROTEIN TYROSINE PHOSPHATASE SIGMA; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CAUCASIAN; CONTROLLED STUDY; DISEASE PREDISPOSITION; FEMALE; GENETIC VARIABILITY; GENOTYPE; HOMOZYGOSITY; HUMAN; HYBRIDIZATION; IMPAIRED GLUCOSE TOLERANCE; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; PROTEIN POLYMORPHISM; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM; SWEDEN;

ADULT; DIABETES MELLITUS, TYPE 2; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; LINKAGE DISEQUILIBRIUM; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTOR-LIKE PROTEIN TYROSINE PHOSPHATASES, CLASS 2; SWEDEN; VARIATION (GENETICS);

EID: 35549013306     PISSN: 08044643     EISSN: None     Source Type: Journal    
DOI: 10.1530/EJE-07-0114     Document Type: Article

References (34)

1. Schinner S, Scherbaum WA, Bornstein SR & Barthel A. Molecular mechanisms of insulin resistance. Diabetic Medicine 2005 22 674-682.
2. Luna MTT. Genes and Type 2 diabetes mellitus. Archives of Medical Research 2005 36 210-222.
3. Simpson RW, Shaw JE & Zimmet PZ. The prevention of Type 2 diabetes - lifestyle change or pharmacotherapy? A challenge for the 21st century Diabetes Research and Clinical Practice 2003 59 165-180.
4. McCarthy MI. Progress in defining the molecular basis of Type 2 diabetes mellitus trough susceptibility-gene identification. Human Molecular Genetics 2004 13 R33-R41.
5. Östenson C-G, Sandberg-Nordqvist A-C, Chen J, Hällbrink M, Rotin D, Langel Ü & Efendic S. Overexpression of protein-tyrosine phosphatase PTP is linked to impaired glucose-induced insulin secretion in hereditary diabetic Goto-Kakizaki rats. Biochemical and Biophysical Research Communications 2002 291 945-950.
6. Chagnon MJ, Elchebly M, Uetani N, Dombrowski L, Cheng A, Mooney RA, Marette A & Tremblay M. Altered glucose homeostasis in mice lacking the receptor protein tyrosine phosphatase sigma. Canadian Journal of Physiology and Pharmacology 2006 84 755-763.
7. Andersen JN, Jansen PG, Echwald SM, Morstensen OH, Pukada T, del Vecchio R, Tonks NK & Møller NPH. A genomic perspective on protein tyrosine phosphatases: gene structure, pseudogenes, and genetic disease linkage. FASEB Journal 2004 18 8-30.
8. Chagnon MJ, Uetani N & Tremblay ML. Functional significance of the LAR receptor protein tyrosine phosphatase family in development of disease. Biochemistry and Cell Biology 2004 82 664-675.
9. Zhang W-R, Li P-M, Oswald MA & Goldstein B. Modulation of insulin signal transduction by eutopic overexpression of the receptor-type protein-tyrosine phosphatase LAR. Molecular Endocrinology 2006 10 575-584.
10. Pulido R, Serra-Pages C, Tang M & Streuli M. The LAR/PTP delta/PTP sigma subfamily of transmembrane protein-tyrosine-phosphatases: multiple human LAR, PTP delta, PTP sigma isoforms are expressed in a tissue-specific manner and associate with the LAR-interacting protein LIP.1. PNAS 1995 92 11686-11690.
11. Norris K, Norris F, Kono DH, Vestergaard H, Pedersen O, Theofilopoulos AN & Moller NPH. Expression of protein-tyrosine phosphatases in the major insulin target tissues. FEBS Letters 1997 415 243-248.
12. Malhotra A, Wolford JK & American Diabetes Association GENNID Study Group. Analysis of quantitative traits in the genetics of NIDDM (GENNID) study. Diabetes 2005 54 3007-3014.
13. Carlsson S, Persson P-G, Alvarsson M, Efendic S, Norman A, Svanström L, Östenson C-G & Grill V. Weight history, glucose tolerance and insulin levels in middle-aged Swedish men. American Journal of Epidemiology 1998 148 539-545.
14. Grill V, Persson G, Carlsson S, Norman A, Alvarsson M, Östenson C-G, Svanström L & Efendic S. Family history of diabetes in middle-aged Swedish men is a gender unrelated factor which is associated with insulinopenia in newly diagnosed diabetic subjects. Diabetologia 1999 42 15-23.
15. Agardh EE, Ahlbom A, Andersson T, Efendic S, Grill V, Hallqvist J, Norman A & Östenson C-G. Work stress and low sense of coherence is associated with Type 2 diabetes in middle-aged Swedish women. Diabetes Care 2003 26 719-724.
16. Alberti KG & Zimmet P. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabetic Medicine 1998 15 539.
17. The International HapMap Consortium. A haplotype map of the human genome. Nature 2005 437 1299-1320.
18. Howell WM, Jobs M, Gyllensten U & Brookes AJ. Dynamic allele-specific hybridization: a new method for scoring single nucleotide polymorphisms. Nature Biotechnology 1999 17 87-88.
19. Prince JA, Feuk L, Howell WM, Jobs M, Emahazion T, Blennow K & Brookes AJ. Robust and accurate single nucleotide polymorphism genotyping by dynamic allele-specific hybridization (DASH): design criteria and assay validation. Genome Research 2001 11 229-239.
20. Matthews DR, Rudenski AS, Naylor BA, Treacher DF & Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985 28 412-419.
21. Schneider S, Roessli D & Excoffier L. (2000) Arlequin: A software for population genetics data analysis. Version 2.0. Genetics and Biometry Lab, Department of Anthropology, University of Geneva.
22. Ma J, Möllsten A, Falkhammar H, Brismar K, Dahlquist G, Efendic D & Gu HF. Genetic association of the adiponectin polymorphisms in type 1 diabetes with and without diabetic nephropathy. Journal of Diabetic Complications 2007 21 28-33.
23. Horikawa Y, Oda N, Cox NJ, Li, X, Orho-Melander M, Hara M, Hinokio Y, Lindner TH, Mashima H, Schwarz PEH, del Bosque-Plata L, Horikawa Y, Oda Y, Yoshiuchi I, Colilla S, Polonsky KS, Wei S, Concannon P, Iwasaki N, Schulze J, Baier LJ, Bogardus C, Groop L, Boerwinkle E, Hanis CL & Bell GI. Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus. Nature Genetics 2000 26 163-175.
24. Hara K, Boutin P, Mori Y, Tobe K, Dina C, Yasuda K, Yamauchi T, Otabe S, Okada T, Eto K, Kadowaki H, Hagura R, Akanuma Y, Yazaki Y, Nagai R, Taniyama M, Matsubara K, Yoda M, Nakano Y, Kimura S, Tomita M, Kimura S, Ito C, Froguel P & Kadowaki T. Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population. Diabetes 2002 51 536-540.
25. Baier LJ, Paskasari AP, Yang X, Pratley RE, Hanson RL, Shen G-Q, Mott D, Knowler WC, Cox NJ, Horikawa Y, Oda N, Bell GI & Bogardus C. A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance. Journal of Clinical Investigation 2000 106 R69-R73.
26. Ren J-M, Li P-M, Zhang W-R, Sweet LJ, Cline G, Shulman GI, Livingston JN & Goldstein B. Transgenic mice deficient in the LAR protein-tyrosine phosphatase exhibit profound defects in glucose homeostasis. Diabetes 1998 47 493-497.
27. Zabolotny JM, Kim Y-B, Peroni OD, Kim JK, Pani MA, Boss O, Klaman LD, Kamatkar S, Shulman GI, Kahn BB & Neel BG. Overexpression of the LAR (leukocyte antigen-related) protein-tyrosine phosphatase in muscle causes insulin resistance. PNAS 2001 98 5187-5192.
28. Cheng A, Dubé N, Gu F & Tremblay ML. Coordinated action of protein tyrosine phosphatases in insulin signal transduction. European Journal of Biochemistry 2002 269 1050-1059.
29. Miscio G, Tassi V, Coco A, Soccio T, Di Paola R, Prudente S, Baratta R, Frittitta L, Ludovico O, Padovano L, Dallapiccola B, Di Mario U, De Cosmo S & Trischitta V. The allelic variant of LAR gene promoter - 127 bp T to A is associated with reduced risk of obesity and other features related to insulin resistance. Journal of Molecular Medicine 2004 82 459-466.
30. Gu HF, Efendic S, Nordman S, Östenson C-G, Brismar K, Brookes AJ & Prince JA. Quantitative trait loci near the insulin-degrading enzyme (IDE) gene contribute to variation in plasma insulin levels. Diabetes 2004 53 2137-2142.
31. Nordman S, Ding B, Östenson C-G, Kärvestedt L, Brismar K, Efendic S & Gu HF. Leu7Pro polymorphism in the neuropeptide Y (NPY) gene is associated with impaired glucose tolerance and Type 2 diabetes in Swedish men. Experimental and Clinical Endocrinology and Diabetes 2005 205 282-287.
32. O'Donnell CJ, Lindpaintner K, Larson MG, Rao VS, Ordovas JM, Schaefer EJ, Myers RH & Levy D. Evidence for association and genetic linkage of the angiotensin-converting enzyme locus with hypertension and blood pressure in men but not in women in the Framingham Heart Study. Circulation 1998 97 1766-1772.
33. Wittrup HH, Tybjaerg-Hansen A, Steffensen R, Deeb SS, Brunzell JD, Jensen G & Nordestgaard BG. Mutations in the lipoprotein lipase gene associated with ischemic heart disease in men: the Copenhagen city heart study. Arteriosclerosis, Thrombosis, and Vascular Biology 1999 19 1535-1540.
34. McCarthy JJ, Meyer J, Moliterno DJ, Newby LK, Rogers WJ & Topol EJ. Evidence for substantial effect modification by gender in a large-scale genetic association study of the metabolic syndrome among coronary heart disease patients. Human Genetics 2003 114 87-98.