-
1
-
-
34248136828
-
Inflammatory bowel disease: Cause and immunobiology
-
Baumgart DC, Carding SR. Inflammatory bowel disease: cause and immunobiology. Lancet 2007 369 : 1627 40.
-
(2007)
Lancet
, vol.369
, pp. 1627-40
-
-
Baumgart, D.C.1
Carding, S.R.2
-
2
-
-
35648952166
-
Common pathways in Crohn's disease and other inflammatory diseases revealed by genomics
-
Massey D, Parkes M. Common pathways in Crohn's disease and other inflammatory diseases revealed by genomics. Gut 2007 56 : 1489 92.
-
(2007)
Gut
, vol.56
, pp. 1489-92
-
-
Massey, D.1
Parkes, M.2
-
3
-
-
0035978651
-
Association of NOD2 leucine rich repeat variants with susceptibility to Crohn's disease
-
Hugot J, Chamaillard M, Zouali H, et al. Association of NOD2 leucine rich repeat variants with susceptibility to Crohn's disease. Nature 2001 411 : 599 603.
-
(2001)
Nature
, vol.411
, pp. 599-603
-
-
Hugot, J.1
Chamaillard, M.2
Zouali, H.3
-
4
-
-
0035978533
-
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
-
Ogura Y, Bonen D, Inohara N, et al. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 2001 411 : 603 6.
-
(2001)
Nature
, vol.411
, pp. 603-6
-
-
Ogura, Y.1
Bonen, D.2
Inohara, N.3
-
5
-
-
33845340501
-
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene
-
Duerr RH, Taylor KD, Brant SR, et al. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science 2006 314 : 1461 3.
-
(2006)
Science
, vol.314
, pp. 1461-3
-
-
Duerr, R.H.1
Taylor, K.D.2
Brant, S.R.3
-
6
-
-
34249030920
-
IL-23 receptor (IL-23R) gene protects against pediatric Crohn's disease
-
Dubinsky MC, Wang D, Picornell Y, et al. IL-23 receptor (IL-23R) gene protects against pediatric Crohn's disease. Inflamm Bowel Dis 2007 13 : 511 5.
-
(2007)
Inflamm Bowel Dis
, vol.13
, pp. 511-5
-
-
Dubinsky, M.C.1
Wang, D.2
Picornell, Y.3
-
7
-
-
34247554965
-
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
-
Rioux JD, Xavier RJ, Taylor KD, et al. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet 2007 39 : 596 604.
-
(2007)
Nat Genet
, vol.39
, pp. 596-604
-
-
Rioux, J.D.1
Xavier, R.J.2
Taylor, K.D.3
-
8
-
-
34247579326
-
Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4
-
Libioulle C, Louis E, Hansoul S, et al. Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4. PLoS Genet 2007 3 : e58.
-
(2007)
PLoS Genet
, vol.3
-
-
Libioulle, C.1
Louis, E.2
Hansoul, S.3
-
9
-
-
34247560627
-
IL23R variation determines susceptibility but not disease phenotype in inflammatory bowel disease
-
Tremelling M, Cummings F, Fisher SA, et al. IL23R variation determines susceptibility but not disease phenotype in inflammatory bowel disease. Gastroenterology 2007 132 : 1657 64.
-
(2007)
Gastroenterology
, vol.132
, pp. 1657-64
-
-
Tremelling, M.1
Cummings, F.2
Fisher, S.A.3
-
10
-
-
84969213492
-
Genome-wide associations study of 14,000 cases of seven common diseases and 3,000 shared controls
-
Welcome Trust Case Control Consortium.
-
Welcome Trust Case Control Consortium. Genome-wide associations study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007 447 : 661 78.
-
(2007)
Nature
, vol.447
, pp. 661-78
-
-
-
11
-
-
33846627302
-
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
-
Hampe J, Franke A, Rosenstiel P, et al. A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nat Genet 2007 39 : 207 11.
-
(2007)
Nat Genet
, vol.39
, pp. 207-11
-
-
Hampe, J.1
Franke, A.2
Rosenstiel, P.3
-
12
-
-
34247566585
-
A nonsynonymous SNP in ATG16L1 predisposes to ileal Crohn's disease and is independent of CARD15 and IBD5
-
Prescott NJ, Fisher SA, Franke A, et al. A nonsynonymous SNP in ATG16L1 predisposes to ileal Crohn's disease and is independent of CARD15 and IBD5. Gastroenterology 2007 132 : 1665 71.
-
(2007)
Gastroenterology
, vol.132
, pp. 1665-71
-
-
Prescott, N.J.1
Fisher, S.A.2
Franke, A.3
-
13
-
-
28444452580
-
Myosin IXB variant increases the risk of celiac disease and points toward a primary intestinal barrier defect
-
Monsuur AJ, de Bakker PIW, Alizadeh BZ, et al. Myosin IXB variant increases the risk of celiac disease and points toward a primary intestinal barrier defect. Nat Genet 2005 12 : 1341 4.
-
(2005)
Nat Genet
, vol.12
, pp. 1341-4
-
-
Monsuur, A.J.1
De Bakker, P.I.W.2
Alizadeh, B.Z.3
-
14
-
-
0141817736
-
A major non-HLA locus in celiac disease maps to chromosome 19
-
van Belzen MJ, Meijer JW, Sandkuijl LA, et al. A major non-HLA locus in celiac disease maps to chromosome 19. Gastroenterology 2003 125 : 1032 41.
-
(2003)
Gastroenterology
, vol.125
, pp. 1032-41
-
-
Van Belzen, M.J.1
Meijer, J.W.2
Sandkuijl, L.A.3
-
15
-
-
11144354272
-
Inflammatory bowel disease susceptibility loci defined by genome scan meta-analysis of 1952 affected relative pairs
-
van Heel DA, Fisher SA, Kirby A, Daly MJ, Rioux JD, Lewis CM. Inflammatory bowel disease susceptibility loci defined by genome scan meta-analysis of 1952 affected relative pairs. Hum Mol Genet 2004 13 : 763 70.
-
(2004)
Hum Mol Genet
, vol.13
, pp. 763-70
-
-
Van Heel, D.A.1
Fisher, S.A.2
Kirby, A.3
Daly, M.J.4
Rioux, J.D.5
Lewis, C.M.6
-
16
-
-
0033910870
-
Genomewide search in Canadian families with inflammatory bowel disease reveals two novel susceptibility loci
-
Rioux JD, Silverberg MS, Daly MJ, et al. Genomewide search in Canadian families with inflammatory bowel disease reveals two novel susceptibility loci. Am J Hum Genet 2000 66 : 1863 70.
-
(2000)
Am J Hum Genet
, vol.66
, pp. 1863-70
-
-
Rioux, J.D.1
Silverberg, M.S.2
Daly, M.J.3
-
17
-
-
0037023728
-
Myosin-IXb is a single-headed and processive motor
-
Post PL, Tyska MJ, O'Connell CB, Johung K, Hayward A, Mooseker MS. Myosin-IXb is a single-headed and processive motor. J Biol Chem 2002 277 : 11679 83.
-
(2002)
J Biol Chem
, vol.277
, pp. 11679-83
-
-
Post, P.L.1
Tyska, M.J.2
O'Connell, C.B.3
Johung, K.4
Hayward, A.5
Mooseker, M.S.6
-
18
-
-
3242705077
-
RhoA, Rac1, and Cdc42 exert distinct effects on epithelial barrier via selective structural and biochemical modulation of junctional proteins and F-actin
-
Bruewer M, Hopkins AM, Hobert ME, Nusrat A, Madara JL. RhoA, Rac1, and Cdc42 exert distinct effects on epithelial barrier via selective structural and biochemical modulation of junctional proteins and F-actin. Am J Physiol Cell Physiol 2004 287 : C327 35.
-
(2004)
Am J Physiol Cell Physiol
, vol.287
-
-
Bruewer, M.1
Hopkins, A.M.2
Hobert, M.E.3
Nusrat, A.4
Madara, J.L.5
-
19
-
-
0037648405
-
Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease
-
Ueda H, Howson JM, Esposito L, et al. Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease. Nature 2003 423 : 506 11.
-
(2003)
Nature
, vol.423
, pp. 506-11
-
-
Ueda, H.1
Howson, J.M.2
Esposito, L.3
-
20
-
-
3242713277
-
A missense single nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis
-
Begovich AB, Carlton VE, Honigberg LA, et al. A missense single nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis. Am J Hum Genet 2004 75 : 330 7.
-
(2004)
Am J Hum Genet
, vol.75
, pp. 330-7
-
-
Begovich, A.B.1
Carlton, V.E.2
Honigberg, L.A.3
-
21
-
-
12144291502
-
A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes
-
Bottini N, Musumeci L, Alonso A, et al. A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes. Nat Genet 2004 36 : 337 8.
-
(2004)
Nat Genet
, vol.36
, pp. 337-8
-
-
Bottini, N.1
Musumeci, L.2
Alonso, A.3
-
22
-
-
33748436534
-
Association analysis of MYO9B gene polymorphisms and inflammatory bowel disease in a Norwegian cohort
-
IBSEN Study Group
-
Amundsen SS, Vatn M, IBSEN Study Group, Wijmenga C, Sollid LM, Lie BA. Association analysis of MYO9B gene polymorphisms and inflammatory bowel disease in a Norwegian cohort. Tissue Antigens 2006 68 : 249 52.
-
(2006)
Tissue Antigens
, vol.68
, pp. 249-52
-
-
Amundsen, S.S.1
Vatn, M.2
Wijmenga, C.3
Sollid, L.M.4
Lie, B.A.5
-
23
-
-
33845622964
-
Genetic variation in myosin IXB is associated with ulcerative colitis
-
Van Bodegraven AA, Curley CR, Hunt KA, Monsuur AJ, Linskens RK, Onnie CM. Genetic variation in myosin IXB is associated with ulcerative colitis. Gastroenterology 2006 131 : 1768 74.
-
(2006)
Gastroenterology
, vol.131
, pp. 1768-74
-
-
Van Bodegraven, A.A.1
Curley, C.R.2
Hunt, K.A.3
Monsuur, A.J.4
Linskens, R.K.5
Onnie, C.M.6
-
24
-
-
34548120887
-
MYO9B polymorphisms in patients with inflammatory bowel disease
-
Nunez C, Oliver J, Mendoza JL, et al. MYO9B polymorphisms in patients with inflammatory bowel disease. Gut 2007 56 : 1321 2.
-
(2007)
Gut
, vol.56
, pp. 1321-2
-
-
Nunez, C.1
Oliver, J.2
Mendoza, J.L.3
-
25
-
-
0037043658
-
Inflammatory bowel disease
-
Podolski DK. Inflammatory bowel disease. N Engl J Med 2002 347 : 417 29.
-
(2002)
N Engl J Med
, vol.347
, pp. 417-29
-
-
Podolski, D.K.1
-
27
-
-
33646246756
-
Increased intestinal permeability and NOD2 variants in familial and sporadic Crohn's disease
-
D'Inca R, Annese V, di Leo V, et al. Increased intestinal permeability and NOD2 variants in familial and sporadic Crohn's disease. Aliment Pharmacol Ther 2006 23 : 1455 61.
-
(2006)
Aliment Pharmacol Ther
, vol.23
, pp. 1455-61
-
-
D'Inca, R.1
Annese, V.2
Di Leo, V.3
-
28
-
-
84894353884
-
Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: Report of a Working Party of the 2005 Montreal World Congress of Gastroenterology
-
Silverberg MS, Satsangi J, Ahmad T, et al. Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a Working Party of the 2005 Montreal World Congress of Gastroenterology. Can J Gastroenterol 2005 19 (Suppl. A 5 36.
-
(2005)
Can J Gastroenterol
, vol.19
, pp. 5-36
-
-
Silverberg, M.S.1
Satsangi, J.2
Ahmad, T.3
-
29
-
-
0035496230
-
The common genetic hypothesis of autoimmune/inflammatory disease
-
Becker KG. The common genetic hypothesis of autoimmune/inflammatory disease. Curr Opin Allergy Clin Immunol 2001 1 : 399 405.
-
(2001)
Curr Opin Allergy Clin Immunol
, vol.1
, pp. 399-405
-
-
Becker, K.G.1
-
30
-
-
34250365731
-
Links MYO9B gene polymorphisms are associated with autoimmune diseases in Spanish population
-
Sánchez E, Alizadeh BZ, Valdigem G, et al. Links MYO9B gene polymorphisms are associated with autoimmune diseases in Spanish population. Hum Immunol 2007 68 : 610 5.
-
(2007)
Hum Immunol
, vol.68
, pp. 610-5
-
-
Sánchez, E.1
Alizadeh, B.Z.2
Valdigem, G.3
-
31
-
-
34347335667
-
Guilt beyond a reasonable doubt
-
Altshuler D, Daly M. Guilt beyond a reasonable doubt. Nat Genet 2007 39 : 813 5.
-
(2007)
Nat Genet
, vol.39
, pp. 813-5
-
-
Altshuler, D.1
Daly, M.2
-
32
-
-
0037023728
-
Myosin-IXb is a single-headed and processive motor
-
Post PL, Tyska MJ, O'Connell CB, Johung K, Hayward A, Mooseker MSJ. Myosin-IXb is a single-headed and processive motor. Biol Chem 2002 277 : 11679 83.
-
(2002)
Biol Chem
, vol.277
, pp. 11679-83
-
-
Post, P.L.1
Tyska, M.J.2
O'Connell, C.B.3
Johung, K.4
Hayward, A.5
Mooseker, M.S.J.6
-
33
-
-
0036222522
-
Myosin IXb is a single-headed minus-end-directed processive motor
-
Inoue A, Saito J, Ikebe R, Ikebe M. Myosin IXb is a single-headed minus-end-directed processive motor. Nat Cell Biol 2002 4 : 302 6.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 302-6
-
-
Inoue, A.1
Saito, J.2
Ikebe, R.3
Ikebe, M.4
-
34
-
-
0029991890
-
Human myosin-IXb, an unconventional myosin with a chimerin-like rho/rac GTPase-activating protein domain in its tail
-
Wirth JA, Jensen KA, Post PL, Bement WM, Mooseker MS. Human myosin-IXb, an unconventional myosin with a chimerin-like rho/rac GTPase-activating protein domain in its tail. J Cell Sci 1996 109 : 653 61.
-
(1996)
J Cell Sci
, vol.109
, pp. 653-61
-
-
Wirth, J.A.1
Jensen, K.A.2
Post, P.L.3
Bement, W.M.4
Mooseker, M.S.5
-
35
-
-
0036644975
-
Guanine nucleotide exchange factors for Rho GTPases: Turning on the switch
-
Schmidt A, Hall A. Guanine nucleotide exchange factors for Rho GTPases: turning on the switch. Genes Dev 2002 16 : 1587 609.
-
(2002)
Genes Dev
, vol.16
, pp. 1587-609
-
-
Schmidt, A.1
Hall, A.2
-
36
-
-
34247232108
-
The myosin IXb motor activity targets the myosin IXb RhoGAP domain as cargo to sites of actin polymerization
-
Van den Boom F, Dussmann H, Uhlenbrock K, Abouhamed M, Bahler M. The myosin IXb motor activity targets the myosin IXb RhoGAP domain as cargo to sites of actin polymerization. Mol Biol Cell 2007 18 : 1507 18.
-
(2007)
Mol Biol Cell
, vol.18
, pp. 1507-18
-
-
Van Den Boom, F.1
Dussmann, H.2
Uhlenbrock, K.3
Abouhamed, M.4
Bahler, M.5
-
37
-
-
3042610165
-
Intestinal epithelial cell regulation of mucosal inflammation
-
Yu Y, Sitaraman S, Gewirtz AT. Intestinal epithelial cell regulation of mucosal inflammation. Immunol Res 2004 29 : 55 68.
-
(2004)
Immunol Res
, vol.29
, pp. 55-68
-
-
Yu, Y.1
Sitaraman, S.2
Gewirtz, A.T.3
-
38
-
-
0030823372
-
Clustering of increased small intestinal permeability in families with Crohn's disease
-
Peeters M, Greypens B, Claus D, et al. Clustering of increased small intestinal permeability in families with Crohn's disease. Gastroenterology 1997 113 : 802 7.
-
(1997)
Gastroenterology
, vol.113
, pp. 802-7
-
-
Peeters, M.1
Greypens, B.2
Claus, D.3
-
39
-
-
15544382565
-
Immunity, inflammation, and allergy in the gut
-
McDonald TT, Monteleone G. Immunity, inflammation, and allergy in the gut. Science 2005 307 : 1920 5.
-
(2005)
Science
, vol.307
, pp. 1920-5
-
-
McDonald, T.T.1
Monteleone, G.2
-
40
-
-
20444469581
-
Inflammatory bowel disease in patients with celiac disease
-
Yang A, Chen Y, Scherl E, Neugut AI, Bhagat G, Green PH. Inflammatory bowel disease in patients with celiac disease. Inflamm Bowel Dis 2005 11 : 528 32.
-
(2005)
Inflamm Bowel Dis
, vol.11
, pp. 528-32
-
-
Yang, A.1
Chen, Y.2
Scherl, E.3
Neugut, A.I.4
Bhagat, G.5
Green, P.H.6
-
41
-
-
33144473772
-
Genetic basis for increased intestinal permeability in families with Crohn's disease: Role of CARD15 3020insC mutation?
-
Buhner S, Bunung S, Genschel J, et al. Genetic basis for increased intestinal permeability in families with Crohn's disease: role of CARD15 3020insC mutation? Gut 2006 55 : 324 47.
-
(2006)
Gut
, vol.55
, pp. 324-47
-
-
Buhner, S.1
Bunung, S.2
Genschel, J.3
|