메뉴 건너뛰기




Volumn 377, Issue 4-6, 2008, Pages 449-462

Signal transduction underlying the control of urinary bladder smooth muscle tone by muscarinic receptors and β-adrenoceptors

Author keywords

adrenoceptor; BKCa channel; Bladder; cAMP; L type Ca2+ channel; Muscarinic receptor; Phospholipase C; Rho kinase

Indexed keywords

1 [2 (4 METHOXYPHENYL) 2 [3 (4 METHOXYPHENYL)PROPOXY]ETHYL] 1H IMIDAZOLE; 1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; 2 MORPHOLINO 8 PHENYLCHROMONE; 4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; 4 CHLOROMERCURIBENZOIC ACID; ADENYLATE CYCLASE; BETA ADRENERGIC RECEPTOR; CALPHOSTIN; CARBACHOL; CHARYBDOTOXIN; CHELERYTHRINE; CYCLIC AMP; FASUDIL; GLIBENCLAMIDE; IBERIOTOXIN; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL ALPHA SUBUNIT; MUSCARINIC M3 RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE A; PHOSPHOLIPASE C; PHOSPHOLIPASE D; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; RHO KINASE; TRICYCLO[4.3.0.1]DECAN 9 YL XANTHOGENATE; U 126; VOLTAGE GATED CALCIUM CHANNEL;

EID: 45849136365     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-007-0208-0     Document Type: Conference Paper
Times cited : (141)

References (157)
  • 2
    • 0028916971 scopus 로고
    • Involvement of protein kinase C activation in a2-adrenoceptor-mediated contractions of rabbit saphenous vein
    • Aburto T, Jinsi A, Zhu Q, Deth RC (1995) Involvement of protein kinase C activation in a2-adrenoceptor-mediated contractions of rabbit saphenous vein. Eur J Pharmacol 277:35-44
    • (1995) Eur J Pharmacol , vol.277 , pp. 35-44
    • Aburto, T.1    Jinsi, A.2    Zhu, Q.3    Deth, R.C.4
  • 4
    • 0037278832 scopus 로고    scopus 로고
    • Comparison of signalling mechanisms involved in rat mesenteric microvessel contraction by noradrenaline and sphingosylphosphorylcholine
    • Altmann C, Steenpass V, Czyborra P, Hein P, Michel MC (2003) Comparison of signalling mechanisms involved in rat mesenteric microvessel contraction by noradrenaline and sphingosylphosphorylcholine. Br J Pharmacol 138:261-271
    • (2003) Br J Pharmacol , vol.138 , pp. 261-271
    • Altmann, C.1    Steenpass, V.2    Czyborra, P.3    Hein, P.4    Michel, M.C.5
  • 6
    • 0033627045 scopus 로고    scopus 로고
    • Treatment of overactive bladder: Other drug mechanisms
    • Suppl 5A
    • Andersson KE (2000) Treatment of overactive bladder: other drug mechanisms. Urology 55(Suppl 5A):51-57
    • (2000) Urology , vol.55 , pp. 51-57
    • Andersson, K.E.1
  • 7
    • 32944466280 scopus 로고    scopus 로고
    • Tachykinins: Role in detrusor overactivity?
    • Andersson KE (2006) Tachykinins: role in detrusor overactivity? Eur Urol 49:423-425
    • (2006) Eur Urol , vol.49 , pp. 423-425
    • Andersson, K.E.1
  • 8
    • 3042637079 scopus 로고    scopus 로고
    • Urinary bladder contraction and relaxation: Physiology and pathophysiology
    • Andersson KE, Arner A (2004) Urinary bladder contraction and relaxation: physiology and pathophysiology. Physiol Rev 84:935-986
    • (2004) Physiol Rev , vol.84 , pp. 935-986
    • Andersson, K.E.1    Arner, A.2
  • 9
  • 10
    • 0035929583 scopus 로고    scopus 로고
    • Involvement of phospholipase D in sphingosine 1-phosphate-induced activation of phosphatidylinositol 3-kinase and Akt in Chinese hamster ovary cells overexpressing EDG3
    • Banno Y, Takuwa Y, Akao Y, Okamoto H, Osawa Y, Naganawa T, Nakashima S, Suh PG, Nozawa Y (2001) Involvement of phospholipase D in sphingosine 1-phosphate-induced activation of phosphatidylinositol 3-kinase and Akt in Chinese hamster ovary cells overexpressing EDG3. J Biol Chem 276:35622-35628
    • (2001) J Biol Chem , vol.276 , pp. 35622-35628
    • Banno, Y.1    Takuwa, Y.2    Akao, Y.3    Okamoto, H.4    Osawa, Y.5    Naganawa, T.6    Nakashima, S.7    Suh, P.G.8    Nozawa, Y.9
  • 11
    • 0027324496 scopus 로고
    • ATP-sensitive potassium channels in smooth muscle cells from guinea pig urinary bladder
    • Bonev AD, Nelson MT (1993a) ATP-sensitive potassium channels in smooth muscle cells from guinea pig urinary bladder. Am J Physiol 264:C1190-C1200
    • (1993) Am J Physiol , vol.264
    • Bonev, A.D.1    Nelson, M.T.2
  • 13
    • 0026625004 scopus 로고
    • Ion channels and control of contractile activity in urinary bladder smooth muscle
    • Suppl 2
    • Brading AF (1992) Ion channels and control of contractile activity in urinary bladder smooth muscle. Jpn J Pharmacol 58(Suppl 2):120P-127P
    • (1992) Jpn J Pharmacol , vol.58
    • Brading, A.F.1
  • 14
    • 31144443897 scopus 로고    scopus 로고
    • 3 muscarinic receptor activation of urinary bladder contractile signal transduction. II. Denervated rat bladder
    • 3 muscarinic receptor activation of urinary bladder contractile signal transduction. II. Denervated rat bladder. J Pharmacol Exp Ther 316:875-880
    • (2006) J Pharmacol Exp Ther , vol.316 , pp. 875-880
    • Braverman, A.S.1    Doumanian, L.R.2    Ruggieri Sr., M.R.3
  • 15
    • 31144433898 scopus 로고    scopus 로고
    • 3 muscarinic receptor activation of urinary bladder contractile signal transduction. I. Normal rat bladder
    • 3 muscarinic receptor activation of urinary bladder contractile signal transduction. I. Normal rat bladder. J Pharmacol Exp Ther 316:869-874
    • (2006) J Pharmacol Exp Ther , vol.316 , pp. 869-874
    • Braverman, A.S.1    Tibb, A.S.2    Ruggieri Sr., M.R.3
  • 17
    • 0036176599 scopus 로고    scopus 로고
    • Spontaneous phasic activity of the pig urinary bladder smooth muscle: Characteristics and sensitivity to potassium channel modulators
    • Buckner SA, Milicic I, Daza AV, Coghlan MJ, Gopalakrishnan M (2002) Spontaneous phasic activity of the pig urinary bladder smooth muscle: characteristics and sensitivity to potassium channel modulators. Br J Pharmacol 135:639-648
    • (2002) Br J Pharmacol , vol.135 , pp. 639-648
    • Buckner, S.A.1    Milicic, I.2    Daza, A.V.3    Coghlan, M.J.4    Gopalakrishnan, M.5
  • 20
    • 0027208248 scopus 로고
    • Muscarinic receptors-characterization, coupling and function
    • Caulfield MP (1993) Muscarinic receptors-characterization, coupling and function. Pharmacol Ther 58:319-379
    • (1993) Pharmacol Ther , vol.58 , pp. 319-379
    • Caulfield, M.P.1
  • 21
    • 0031774720 scopus 로고    scopus 로고
    • International Union of Pharmacology. XVII. Classification of muscarinic acetylcholine receptors
    • Caulfield MP, Birdsall NJ (1998) International Union of Pharmacology. XVII. Classification of muscarinic acetylcholine receptors. Pharmacol Rev 50:279-290
    • (1998) Pharmacol Rev , vol.50 , pp. 279-290
    • Caulfield, M.P.1    Birdsall, N.J.2
  • 22
    • 0032922827 scopus 로고    scopus 로고
    • Ryanodine receptors in human bladder smooth muscle
    • Chambers P, Neal DE, Gillespie JI (1999) Ryanodine receptors in human bladder smooth muscle. Exp Physiol 84:41-46
    • (1999) Exp Physiol , vol.84 , pp. 41-46
    • Chambers, P.1    Neal, D.E.2    Gillespie, J.I.3
  • 23
    • 33645579950 scopus 로고    scopus 로고
    • Increased basal phosphorylation of detrusor smooth muscle myosin in alloxan-induced diabetic rabbit is mediated by upregulation of Rho-kinase b and CPI-17
    • Chang S, Hypolite JA, Disanto ME, Changolkar A, Wein AJ, Chacko S (2006) Increased basal phosphorylation of detrusor smooth muscle myosin in alloxan-induced diabetic rabbit is mediated by upregulation of Rho-kinase b and CPI-17. Am J Physiol 290:F650-F656
    • (2006) Am J Physiol , vol.290
    • Chang, S.1    Hypolite, J.A.2    Disanto, M.E.3    Changolkar, A.4    Wein, A.J.5    Chacko, S.6
  • 24
    • 33645779772 scopus 로고    scopus 로고
    • Effect of an ATP-sensitive potassium channel opener in subjects with overactive bladder: A randomized, double-blind, placebo-controlled study (ZD0947IL/0004)
    • Chapple CR, Patroneva A, Raines SR (2006) Effect of an ATP-sensitive potassium channel opener in subjects with overactive bladder: a randomized, double-blind, placebo-controlled study (ZD0947IL/0004). Eur Urol 49:879-886
    • (2006) Eur Urol , vol.49 , pp. 879-886
    • Chapple, C.R.1    Patroneva, A.2    Raines, S.R.3
  • 27
    • 0031110583 scopus 로고    scopus 로고
    • Effects of protein tyrosine kinase inhibitors on contractility of isolated bronchioles of the rat
    • Chopra LC, Hucks D, Twort CH, Ward JP (1997) Effects of protein tyrosine kinase inhibitors on contractility of isolated bronchioles of the rat. Am J Respir Cell Mol Biol 16:372-378
    • (1997) Am J Respir Cell Mol Biol , vol.16 , pp. 372-378
    • Chopra, L.C.1    Hucks, D.2    Twort, C.H.3    Ward, J.P.4
  • 30
    • 0036006307 scopus 로고    scopus 로고
    • Potassium channel KVa1 subunit expression and function in human detrusor muscle
    • Davies AM, Batchelor TJ, Eardley I, Beech DJ (2002) Potassium channel KVa1 subunit expression and function in human detrusor muscle. J Urol 167:1881-1886
    • (2002) J Urol , vol.167 , pp. 1881-1886
    • Davies, A.M.1    Batchelor, T.J.2    Eardley, I.3    Beech, D.J.4
  • 31
    • 0027238131 scopus 로고
    • Inhibitory effect of cromakalim in human detrusor muscle is mediated by glibenclamide-sensitive potassium channels
    • de Moura RS, de Mello RF, D'Aguinaga S (1993) Inhibitory effect of cromakalim in human detrusor muscle is mediated by glibenclamide-sensitive potassium channels. J Urol 149:1174-1177
    • (1993) J Urol , vol.149 , pp. 1174-1177
    • De Moura, R.S.1    De Mello, R.F.2    D'Aguinaga, S.3
  • 32
    • 0033847565 scopus 로고    scopus 로고
    • Alterations in G-proteins and β-adrenergic responsive adenylyl cyclase in rat urinary bladder during aging
    • Derweesh IH, Wheeler MA, Weiss RM (2000) Alterations in G-proteins and β-adrenergic responsive adenylyl cyclase in rat urinary bladder during aging. J Pharmacol Exp Ther 294:969-974
    • (2000) J Pharmacol Exp Ther , vol.294 , pp. 969-974
    • Derweesh, I.H.1    Wheeler, M.A.2    Weiss, R.M.3
  • 33
    • 0031722643 scopus 로고    scopus 로고
    • A role for MAP kinase in differentiated smooth muscle contraction evoked by alpha-adrenoceptor stimulation
    • Dessy C, Kim I, Sougnez CL, Laporte R, Morgan KG (1998) A role for MAP kinase in differentiated smooth muscle contraction evoked by alpha-adrenoceptor stimulation. Am J Physiol 275:C1081-C1086
    • (1998) Am J Physiol , vol.275
    • Dessy, C.1    Kim, I.2    Sougnez, C.L.3    Laporte, R.4    Morgan, K.G.5
  • 35
    • 33744485804 scopus 로고    scopus 로고
    • Involvement of Rho kinase and protein kinase C in carbachol-induced calcium sensitization in β-escin skinned rat and guinea-pig bladders
    • Durlu-Kandilci NT, Brading AF (2006) Involvement of Rho kinase and protein kinase C in carbachol-induced calcium sensitization in β-escin skinned rat and guinea-pig bladders. Br J Pharmacol 148:376-384
    • (2006) Br J Pharmacol , vol.148 , pp. 376-384
    • Durlu-Kandilci, N.T.1    Brading, A.F.2
  • 36
    • 0026072983 scopus 로고
    • Comparison of the effects of several potassium-channel openers on rat bladder and rat portal vein in vitro
    • Edwards G, Henshaw M, Miller M, Weston AH (1991) Comparison of the effects of several potassium-channel openers on rat bladder and rat portal vein in vitro. Br J Pharmacol 102:679-680
    • (1991) Br J Pharmacol , vol.102 , pp. 679-680
    • Edwards, G.1    Henshaw, M.2    Miller, M.3    Weston, A.H.4
  • 37
    • 0030809764 scopus 로고    scopus 로고
    • Subtypes of the muscarinic receptor in smooth muscle
    • Ehlert FJ, Ostrom RS, Sawyer GW (1997) Subtypes of the muscarinic receptor in smooth muscle. Life Sci 61:1729-1740
    • (1997) Life Sci , vol.61 , pp. 1729-1740
    • Ehlert, F.J.1    Ostrom, R.S.2    Sawyer, G.W.3
  • 38
    • 0029013930 scopus 로고
    • Muscarinic acetylcholine receptors: Signal transduction through multiple effectors
    • Felder CC (1995) Muscarinic acetylcholine receptors: signal transduction through multiple effectors. FASEB J 9:619-625
    • (1995) FASEB J , vol.9 , pp. 619-625
    • Felder, C.C.1
  • 39
    • 33744810333 scopus 로고    scopus 로고
    • β-adrenoceptors and potassium channels
    • Ferro A (2006) β-adrenoceptors and potassium channels. Naunyn Schmiedebergs Arch Pharmacol 373:183-185
    • (2006) Naunyn Schmiedebergs Arch Pharmacol , vol.373 , pp. 183-185
    • Ferro, A.1
  • 41
    • 0347342443 scopus 로고    scopus 로고
    • Signal transduction underlying carbachol-induced contraction of rat urinary bladder. II. Protein kinases
    • Fleichman M, Schneider T, Fetscher C, Michel MC (2004) Signal transduction underlying carbachol-induced contraction of rat urinary bladder. II. Protein kinases. J Pharmacol Exp Ther 308:54-58
    • (2004) J Pharmacol Exp Ther , vol.308 , pp. 54-58
    • Fleichman, M.1    Schneider, T.2    Fetscher, C.3    Michel, M.C.4
  • 42
    • 0024524261 scopus 로고
    • The effect of cromakalim on the smooth muscle of the guinea-pig urinary bladder
    • Foster CD, Fujii K, Kingdon J, Brading AF (1989a) The effect of cromakalim on the smooth muscle of the guinea-pig urinary bladder. Br J Pharmacol 97:281-291
    • (1989) Br J Pharmacol , vol.97 , pp. 281-291
    • Foster, C.D.1    Fujii, K.2    Kingdon, J.3    Brading, A.F.4
  • 43
    • 0024520586 scopus 로고
    • The effects of cromakalim on the detrusor muscle of human and pig urinary bladder
    • Foster CD, Speakman MJ, Fujii K, Brading AF (1989b) The effects of cromakalim on the detrusor muscle of human and pig urinary bladder. Br J Urol 63:284-294
    • (1989) Br J Urol , vol.63 , pp. 284-294
    • Foster, C.D.1    Speakman, M.J.2    Fujii, K.3    Brading, A.F.4
  • 44
    • 15744387368 scopus 로고    scopus 로고
    • Does cyclic AMP mediate rat urinary bladder relaxation by isoproterenol?
    • Frazier EP, Matthy MJ, Peters SL, Michel M (2005) Does cyclic AMP mediate rat urinary bladder relaxation by isoproterenol? J Pharmacol Exp Ther 313:260-267
    • (2005) J Pharmacol Exp Ther , vol.313 , pp. 260-267
    • Frazier, E.P.1    Matthy, M.J.2    Peters, S.L.3    Michel, M.4
  • 46
    • 0029148607 scopus 로고
    • 2+ channels in neurotransmission in the rat urinary bladder
    • 2+ channels in neurotransmission in the rat urinary bladder. Br J Pharmacol 116:1595-1598
    • (1995) Br J Pharmacol , vol.116 , pp. 1595-1598
    • Frew, R.1    Lundy, P.M.2
  • 47
    • 0025343682 scopus 로고
    • Potassium channel blockers and the effects of cromakalim on the smooth muscle of the guinea-pig bladder
    • Fujii K, Foster CD, Brading AF, Parekh AB (1990) Potassium channel blockers and the effects of cromakalim on the smooth muscle of the guinea-pig bladder. Br J Pharmacol 99:779-785
    • (1990) Br J Pharmacol , vol.99 , pp. 779-785
    • Fujii, K.1    Foster, C.D.2    Brading, A.F.3    Parekh, A.B.4
  • 49
    • 0027070724 scopus 로고
    • i transients in myocytes from guinea-pig urinary bladder
    • i transients in myocytes from guinea-pig urinary bladder. J Physiol 458:119-137
    • (1992) J Physiol , vol.458 , pp. 119-137
    • Ganitkevich, V.Y.1    Isenberg, G.2
  • 52
    • 0026346288 scopus 로고
    • + channel blockers and cromakalim (BRL 34915) on the mechanical activity of guinea pig detrusor smooth muscle
    • + channel blockers and cromakalim (BRL 34915) on the mechanical activity of guinea pig detrusor smooth muscle. J Pharmacol Exp Ther 259:1158-1164
    • (1991) J Pharmacol Exp Ther , vol.259 , pp. 1158-1164
    • Grant, T.L.1    Zuzack, J.S.2
  • 53
    • 33746047723 scopus 로고    scopus 로고
    • The role of tyrosine kinase in prostaglandin E2 and vanadate-evoked contractions in rabbit duodenum in vitro
    • Grasa L, Arruebo MP, Plaza MA, Murillo MD (2006) The role of tyrosine kinase in prostaglandin E2 and vanadate-evoked contractions in rabbit duodenum in vitro. J Physiol Pharmacol 57:279-289
    • (2006) J Physiol Pharmacol , vol.57 , pp. 279-289
    • Grasa, L.1    Arruebo, M.P.2    Plaza, M.A.3    Murillo, M.D.4
  • 54
    • 0035854086 scopus 로고    scopus 로고
    • Activation of phosphatidylinositol 3 kinase by muscarinic receptors in astrocytoma cells
    • Guizzetti M, Costa LG (2001) Activation of phosphatidylinositol 3 kinase by muscarinic receptors in astrocytoma cells. Neuroreport 12:1639-1642
    • (2001) Neuroreport , vol.12 , pp. 1639-1642
    • Guizzetti, M.1    Costa, L.G.2
  • 55
    • 0027551801 scopus 로고
    • Actions of potassium channel openers in rat detrusor urinae
    • Ha JH, Lee KY, Kim WJ (1993) Actions of potassium channel openers in rat detrusor urinae. J Korean Med Sci 8:53-59
    • (1993) J Korean Med Sci , vol.8 , pp. 53-59
    • Ha, J.H.1    Lee, K.Y.2    Kim, W.J.3
  • 56
    • 32544437047 scopus 로고    scopus 로고
    • Muscarinic receptors in the bladder: From basic research to therapeutics
    • Suppl 2
    • Hegde SS (2006) Muscarinic receptors in the bladder: from basic research to therapeutics. Br J Pharmacol 147(Suppl 2):S80-S87
    • (2006) Br J Pharmacol , vol.147
    • Hegde, S.S.1
  • 57
    • 0030860425 scopus 로고    scopus 로고
    • + channels regulate action potential repolarization in urinary bladder smooth muscle
    • + channels regulate action potential repolarization in urinary bladder smooth muscle. Am J Physiol 273:C110-C117
    • (1997) Am J Physiol , vol.273
    • Heppner, T.J.1    Bonev, A.D.2    Nelson, M.T.3
  • 59
    • 0036623894 scopus 로고    scopus 로고
    • 2+ channels and ryanodine receptors in guinea-pig urinary bladder myocytes
    • 2+ channels and ryanodine receptors in guinea-pig urinary bladder myocytes. J Physiol 541:483-492
    • (2002) J Physiol , vol.541 , pp. 483-492
    • Herrera, G.M.1    Nelson, M.T.2
  • 60
    • 0033881005 scopus 로고    scopus 로고
    • Regulation of urinary bladder smooth muscle contractions by ryanodine receptors and BK and SK channels
    • Herrera GM, Heppner TJ, Nelson MT (2000) Regulation of urinary bladder smooth muscle contractions by ryanodine receptors and BK and SK channels. Am J Physiol 279:R60-R68
    • (2000) Am J Physiol , vol.279
    • Herrera, G.M.1    Heppner, T.J.2    Nelson, M.T.3
  • 62
    • 0141758433 scopus 로고    scopus 로고
    • Urinary bladder instability induced by selective suppression of the murine small conductance calcium-activated potassium (SK3) channel
    • Herrera GM, Pozo MJ, Zvara P, Petkov GV, Bond CT, Adelman JP, Nelson MT (2003) Urinary bladder instability induced by selective suppression of the murine small conductance calcium-activated potassium (SK3) channel. J Physiol 551:893-903
    • (2003) J Physiol , vol.551 , pp. 893-903
    • Herrera, G.M.1    Pozo, M.J.2    Zvara, P.3    Petkov, G.V.4    Bond, C.T.5    Adelman, J.P.6    Nelson, M.T.7
  • 63
    • 0037041186 scopus 로고    scopus 로고
    • The synthesis and structure-activity relationships of 1,3-diaryl 1,2,4-(4H)-triazol-5-ones: A new class of calcium-dependent, large conductance, potassium (maxi-K) channel opener targeted for urge urinary incontinence
    • Hewawasam P, Erway M, Thalody G, Weiner H, Boissard CG, Gribkoff VK, Meanwell NA, Lodge N, Starrett JE Jr (2002) The synthesis and structure-activity relationships of 1,3-diaryl 1,2,4-(4H)-triazol-5-ones: a new class of calcium-dependent, large conductance, potassium (maxi-K) channel opener targeted for urge urinary incontinence. Bioorg Med Chem Lett 12:1117-1120
    • (2002) Bioorg Med Chem Lett , vol.12 , pp. 1117-1120
    • Hewawasam, P.1    Erway, M.2    Thalody, G.3    Weiner, H.4    Boissard, C.G.5    Gribkoff, V.K.6    Meanwell, N.A.7    Lodge, N.8    Starrett Jr., J.E.9
  • 64
    • 1442349847 scopus 로고    scopus 로고
    • Comparative pharmacology of human β-adrenergic receptor subtypes-characterization of stably transfected receptors in CHO cells
    • Hoffmann C, Leitz MR, Oberdorf-Maass S, Lohse MJ, Klotz KN (2004) Comparative pharmacology of human β-adrenergic receptor subtypes-characterization of stably transfected receptors in CHO cells. Naunyn Schmiedebergs Arch Pharmacol 369:151-159
    • (2004) Naunyn Schmiedebergs Arch Pharmacol , vol.369 , pp. 151-159
    • Hoffmann, C.1    Leitz, M.R.2    Oberdorf-Maass, S.3    Lohse, M.J.4    Klotz, K.N.5
  • 65
    • 0034717105 scopus 로고    scopus 로고
    • ATP channels mediate the b2-adrenoceptor agonist-induced relaxation of rat detrusor muscle
    • ATP channels mediate the b2-adrenoceptor agonist-induced relaxation of rat detrusor muscle. Eur J Pharmacol 397:169-176
    • (2000) Eur J Pharmacol , vol.397 , pp. 169-176
    • Hudman, D.1    Elliott, R.A.2    Norman, R.I.3
  • 66
    • 0031754498 scopus 로고    scopus 로고
    • Src kinase and PI 3-kinase as a transduction pathway in ceramide-induced contraction of colonic smooth muscle
    • Ibitayo AI, Tsunoda Y, Nozu F, Owyang C, Bitar KN (1998) Src kinase and PI 3-kinase as a transduction pathway in ceramide-induced contraction of colonic smooth muscle. Am J Physiol 275:G705-G711
    • (1998) Am J Physiol , vol.275
    • Ibitayo, A.I.1    Tsunoda, Y.2    Nozu, F.3    Owyang, C.4    Bitar, K.N.5
  • 67
    • 0036041921 scopus 로고    scopus 로고
    • 2-Aminoethoxydiphenyl borate causes dissociation between membrane electrical and mechanical activity in guinea-pig urinary bladder smooth muscle
    • Imai T, Tanaka Y, Okamoto T, Horinouchi T, Tanaka H, Koike K, Shigenobu K (2002) 2-Aminoethoxydiphenyl borate causes dissociation between membrane electrical and mechanical activity in guinea-pig urinary bladder smooth muscle. Naunyn Schmiedebergs Arch Pharmacol 366:282-285
    • (2002) Naunyn Schmiedebergs Arch Pharmacol , vol.366 , pp. 282-285
    • Imai, T.1    Tanaka, Y.2    Okamoto, T.3    Horinouchi, T.4    Tanaka, H.5    Koike, K.6    Shigenobu, K.7
  • 68
    • 0027997605 scopus 로고
    • A possible role of tyrosine kinases in the regulation of muscarinic receptor-activated cation channels in guinea pig ileum
    • Inoue R, Waniishi Y, Yamada K, Ito Y (1994) A possible role of tyrosine kinases in the regulation of muscarinic receptor-activated cation channels in guinea pig ileum. Biochem Biophys Res Commun 203:1392-1397
    • (1994) Biochem Biophys Res Commun , vol.203 , pp. 1392-1397
    • Inoue, R.1    Waniishi, Y.2    Yamada, K.3    Ito, Y.4
  • 69
    • 0035141402 scopus 로고    scopus 로고
    • Vasoconstrictor actions of isoprostanes via tyrosine kinase and Rho kinase in human and canine pulmonary vascular smooth muscles
    • Janssen LJ, Premji M, Netherton S, Coruzzi J, Lu-Chao H, Cox PG (2001) Vasoconstrictor actions of isoprostanes via tyrosine kinase and Rho kinase in human and canine pulmonary vascular smooth muscles. Br J Pharmacol 132:127-134
    • (2001) Br J Pharmacol , vol.132 , pp. 127-134
    • Janssen, L.J.1    Premji, M.2    Netherton, S.3    Coruzzi, J.4    Lu-Chao, H.5    Cox, P.G.6
  • 70
    • 0034846777 scopus 로고    scopus 로고
    • Dependence of detrusor contractions on calcium sensitization and calcium entry through LOE-908-sensitive channels
    • Jezior JR, Brady JD, Rosenstein DI, McCammon KA, Miner AS, Ratz PH (2001) Dependence of detrusor contractions on calcium sensitization and calcium entry through LOE-908-sensitive channels. Br J Pharmacol 134:78-87
    • (2001) Br J Pharmacol , vol.134 , pp. 78-87
    • Jezior, J.R.1    Brady, J.D.2    Rosenstein, D.I.3    McCammon, K.A.4    Miner, A.S.5    Ratz, P.H.6
  • 71
    • 33750843512 scopus 로고    scopus 로고
    • Communication between tyrosine kinase pathway and myosin light chain kinase pathway in smooth muscle
    • Jin N, Siddiqui RA, English D, Rhoades RA (1996) Communication between tyrosine kinase pathway and myosin light chain kinase pathway in smooth muscle. Am J Physiol 271:H1348-H1355
    • (1996) Am J Physiol , vol.271
    • Jin, N.1    Siddiqui, R.A.2    English, D.3    Rhoades, R.A.4
  • 72
    • 0029890648 scopus 로고    scopus 로고
    • A tyrosine kinase regulates α-adrenoceptor-stimulated contraction and phospholipase D activation in the rat aorta
    • Jinsi A, Paradise J, Deth RC (1996) A tyrosine kinase regulates α-adrenoceptor-stimulated contraction and phospholipase D activation in the rat aorta. Eur J Pharmacol 302:183-190
    • (1996) Eur J Pharmacol , vol.302 , pp. 183-190
    • Jinsi, A.1    Paradise, J.2    Deth, R.C.3
  • 75
    • 10644250809 scopus 로고    scopus 로고
    • Involvement of ryanodine receptors in muscarinic receptor-mediated membrane current oscillation in urinary bladder smooth muscle
    • Kajioka S, Nakayama S, Asano H, Brading AF (2005) Involvement of ryanodine receptors in muscarinic receptor-mediated membrane current oscillation in urinary bladder smooth muscle. Am J Physiol 288:C100-C108
    • (2005) Am J Physiol , vol.288
    • Kajioka, S.1    Nakayama, S.2    Asano, H.3    Brading, A.F.4
  • 76
    • 0035014761 scopus 로고    scopus 로고
    • + channels and gap junctions in urogenital smooth muscle: Implications for improved understanding of urogenital function, disease and therapy
    • + channels and gap junctions in urogenital smooth muscle: implications for improved understanding of urogenital function, disease and therapy. Curr Drug Targets 2:1-20
    • (2001) Curr Drug Targets , vol.2 , pp. 1-20
    • Karicheti, V.1    Christ, G.J.2
  • 77
    • 0022345401 scopus 로고
    • Action potentials and net membrane currents of isolated smooth muscle cells (urinary bladder of the guinea-pig)
    • Klockner U, Isenberg G (1985) Action potentials and net membrane currents of isolated smooth muscle cells (urinary bladder of the guinea-pig). Pflugers Arch 405:329-339
    • (1985) Pflugers Arch , vol.405 , pp. 329-339
    • Klockner, U.1    Isenberg, G.2
  • 78
    • 0034666664 scopus 로고    scopus 로고
    • Ca channels in the relaxation of detrusor muscle via β-adrenoceptors
    • Ca channels in the relaxation of detrusor muscle via β-adrenoceptors. Eur J Pharmacol 404:231-238
    • (2000) Eur J Pharmacol , vol.404 , pp. 231-238
    • Kobayashi, H.1    Chi-Akahane, S.2    Nagao, T.3
  • 81
    • 7044270703 scopus 로고    scopus 로고
    • Investigation of the effect of the c-kit inhibitor Glivec on isolated guinea-pig detrusor preparations
    • Kubota Y, Kajioka S, Biers SM, Yokota E, Kohri K, Brading AF (2004) Investigation of the effect of the c-kit inhibitor Glivec on isolated guinea-pig detrusor preparations. Auton Neurosci 115:64-73
    • (2004) Auton Neurosci , vol.115 , pp. 64-73
    • Kubota, Y.1    Kajioka, S.2    Biers, S.M.3    Yokota, E.4    Kohri, K.5    Brading, A.F.6
  • 83
    • 0030699250 scopus 로고    scopus 로고
    • Acetylcholine agonists stimulate mitogen-activated protein kinase in oligodendrocyte progenitors by muscarinic receptors
    • Larocca JN, Almazan G (1997) Acetylcholine agonists stimulate mitogen-activated protein kinase in oligodendrocyte progenitors by muscarinic receptors. J Neurosci Res 50:743-754
    • (1997) J Neurosci Res , vol.50 , pp. 743-754
    • Larocca, J.N.1    Almazan, G.2
  • 84
    • 0033793583 scopus 로고    scopus 로고
    • Protein kinase C regulates purinergic component of neurogenic contractions in mouse bladder
    • Liu SH, Lin-Shiau SY (2000) Protein kinase C regulates purinergic component of neurogenic contractions in mouse bladder. J Urol 164:1764-1767
    • (2000) J Urol , vol.164 , pp. 1764-1767
    • Liu, S.H.1    Lin-Shiau, S.Y.2
  • 85
    • 0037169605 scopus 로고    scopus 로고
    • 3 receptors and β-adrenoceptor in cultured rat bladder smooth muscle
    • 3 receptors and β-adrenoceptor in cultured rat bladder smooth muscle. Life Sci 70:1159-1172
    • (2002) Life Sci , vol.70 , pp. 1159-1172
    • Ma, F.H.1    Higashira-Hoshi, H.2    Itoh, Y.3
  • 86
    • 0030976303 scopus 로고    scopus 로고
    • Signal transduction in gastrointestinal smooth muscle
    • Makhlouf GM, Murthy KS (1997) Signal transduction in gastrointestinal smooth muscle. Cell Signal 9:269-276
    • (1997) Cell Signal , vol.9 , pp. 269-276
    • Makhlouf, G.M.1    Murthy, K.S.2
  • 87
    • 0025322023 scopus 로고
    • Effects of cromakalim (BRL 34915) and pinacidil on normal and hypertrophied rat detrusor in vitro
    • Malmgren A, Andersson KE, Andersson PO, Fovaeus M, Sjogren C (1990) Effects of cromakalim (BRL 34915) and pinacidil on normal and hypertrophied rat detrusor in vitro. J Urol 143:828-834
    • (1990) J Urol , vol.143 , pp. 828-834
    • Malmgren, A.1    Andersson, K.E.2    Andersson, P.O.3    Fovaeus, M.4    Sjogren, C.5
  • 89
    • 0033022340 scopus 로고    scopus 로고
    • Activation of muscarinic receptors in porcine airway smooth muscle elicits a transient increase in phospholipase D activity
    • Mamoon AM, Smith J, Baker RC, Farley JM (1999) Activation of muscarinic receptors in porcine airway smooth muscle elicits a transient increase in phospholipase D activity. J Biomed Sci 6:97-105
    • (1999) J Biomed Sci , vol.6 , pp. 97-105
    • Mamoon, A.M.1    Smith, J.2    Baker, R.C.3    Farley, J.M.4
  • 90
    • 0026717933 scopus 로고
    • 2+ concentration jumps in excised inside-out multi-channel patches (myocytes from guinea pig urinary bladder)
    • 2+ concentration jumps in excised inside-out multi-channel patches (myocytes from guinea pig urinary bladder). J Gen Physiol 99:841-862
    • (1992) J Gen Physiol , vol.99 , pp. 841-862
    • Markwardt, F.1    Isenberg, G.2
  • 91
    • 0029964321 scopus 로고    scopus 로고
    • Desensitization of muscarinic receptor-coupled inositol phospholipid hydrolysis in human detrusor cultured smooth cells
    • Marsh KA, Harrisss DR, Hill SJ (1996) Desensitization of muscarinic receptor-coupled inositol phospholipid hydrolysis in human detrusor cultured smooth cells. J Urol 155:1439-1443
    • (1996) J Urol , vol.155 , pp. 1439-1443
    • Marsh, K.A.1    Harrisss, D.R.2    Hill, S.J.3
  • 95
    • 33750432148 scopus 로고    scopus 로고
    • Treatment of the overactive bladder syndrome with muscarinic receptor antagonists: A matter of metabolites?
    • Michel MC, Hegde SS (2006) Treatment of the overactive bladder syndrome with muscarinic receptor antagonists: a matter of metabolites? Naunyn Schmiedebergs Arch Pharmacol 374:79-85
    • (2006) Naunyn Schmiedebergs Arch Pharmacol , vol.374 , pp. 79-85
    • Michel, M.C.1    Hegde, S.S.2
  • 96
    • 32544437708 scopus 로고    scopus 로고
    • 2- and β-adrenoceptors in the urinary bladder, urethra and prostate
    • Suppl 2
    • 2- and β-adrenoceptors in the urinary bladder, urethra and prostate. Br J Pharmacol 147(Suppl 2):S88-S119
    • (2006) Br J Pharmacol , vol.147
    • Michel, M.C.1    Vrydag, W.2
  • 97
    • 33847645880 scopus 로고    scopus 로고
    • Proteinase-activated receptors in the lower urinary tract
    • Moffatt JD (2007) Proteinase-activated receptors in the lower urinary tract. Naunyn Schmiedebergs Arch Pharmacol 375:1-9
    • (2007) Naunyn Schmiedebergs Arch Pharmacol , vol.375 , pp. 1-9
    • Moffatt, J.D.1
  • 98
    • 12744260162 scopus 로고    scopus 로고
    • The anticholinergic drug propiverine inhibits the protein kinase C activity in the rat urinary bladder
    • Moritz KU, Walter R, May K, Giessmann T, Siegmund W (2005) The anticholinergic drug propiverine inhibits the protein kinase C activity in the rat urinary bladder. Pharmazie 60:49-51
    • (2005) Pharmazie , vol.60 , pp. 49-51
    • Moritz, K.U.1    Walter, R.2    May, K.3    Giessmann, T.4    Siegmund, W.5
  • 99
    • 1442325422 scopus 로고    scopus 로고
    • Protease-activated receptor-2-mediated contraction of urinary bladder is enhanced in cyclophosphamide-treated rats
    • Nakahara T, Kubota Y, Saito M, Sakamoto K, Ishii K (2004) Protease-activated receptor-2-mediated contraction of urinary bladder is enhanced in cyclophosphamide-treated rats. Naunyn Schmiedebergs Arch Pharmacol 369:212-219
    • (2004) Naunyn Schmiedebergs Arch Pharmacol , vol.369 , pp. 212-219
    • Nakahara, T.1    Kubota, Y.2    Saito, M.3    Sakamoto, K.4    Ishii, K.5
  • 100
    • 0027436450 scopus 로고
    • 2+ channels in smooth muscle cells isolated from the guinea-pig detrusor
    • 2+ channels in smooth muscle cells isolated from the guinea-pig detrusor. J Physiol 471:87-105
    • (1993) J Physiol , vol.471 , pp. 87-105
    • Nakayama, S.1    Brading, A.F.2
  • 103
    • 1642501560 scopus 로고    scopus 로고
    • PI3-kinase upregulation and involvement in spontaneous tone in arteries from DOCA-salt rats: Is p110delta the culprit?
    • Northcott CA, Hayflick JS, Watts SW (2004) PI3-kinase upregulation and involvement in spontaneous tone in arteries from DOCA-salt rats: is p110delta the culprit? Hypertension 43:885-890
    • (2004) Hypertension , vol.43 , pp. 885-890
    • Northcott, C.A.1    Hayflick, J.S.2    Watts, S.W.3
  • 104
    • 0035878634 scopus 로고    scopus 로고
    • 2+ transients and distribution of BK channels and ryanodine receptors in smooth muscle cells of guinea-pig vas deferens and urinary bladder
    • 2+ transients and distribution of BK channels and ryanodine receptors in smooth muscle cells of guinea-pig vas deferens and urinary bladder. J Physiol 534:313-326
    • (2001) J Physiol , vol.534 , pp. 313-326
    • Ohi, Y.1    Yamamura, H.2    Nagano, N.3    Ohya, S.4    Muraki, K.5    Watanabe, M.6    Imaizumi, Y.7
  • 105
    • 33747175707 scopus 로고    scopus 로고
    • Rho kinase: A target for treating urinary bladder dysfunction?
    • Peters SL, Schmidt M, Michel MC (2006) Rho kinase: a target for treating urinary bladder dysfunction? Trends Pharmacol Sci 9:492-497
    • (2006) Trends Pharmacol Sci , vol.9 , pp. 492-497
    • Peters, S.L.1    Schmidt, M.2    Michel, M.C.3
  • 106
    • 22244447729 scopus 로고    scopus 로고
    • + channels by β-adrenoceptors in guinea pig urinary bladder smooth muscle
    • + channels by β-adrenoceptors in guinea pig urinary bladder smooth muscle. Am J Physiol Cell Physiol 288:C1255-C1263
    • (2005) Am J Physiol Cell Physiol , vol.288
    • Petkov, G.V.1    Nelson, M.T.2
  • 108
    • 18144389795 scopus 로고    scopus 로고
    • Rho-kinase inhibition suppresses bladder hyperactivity in spontaneously hypertensive rats
    • Rajasekaran M, Wilkes N, Kuntz S, Albo E (2005) Rho-kinase inhibition suppresses bladder hyperactivity in spontaneously hypertensive rats. Neurourol Urodyn 24:295-300
    • (2005) Neurourol Urodyn , vol.24 , pp. 295-300
    • Rajasekaran, M.1    Wilkes, N.2    Kuntz, S.3    Albo, E.4
  • 109
    • 0033605718 scopus 로고    scopus 로고
    • The role of phosphoinositide 3-kinase lipid products in cell function
    • Rameh LE, Cantley LC (1999) The role of phosphoinositide 3-kinase lipid products in cell function. J Biol Chem 274:8347-8350
    • (1999) J Biol Chem , vol.274 , pp. 8347-8350
    • Rameh, L.E.1    Cantley, L.C.2
  • 110
    • 21844441901 scopus 로고    scopus 로고
    • A role for the P2X receptor in urinary tract physiology and in the pathophysiology of urinary dysfunction
    • Rapp DE, Lyon MB, Bales GT, Cook SP (2005) A role for the P2X receptor in urinary tract physiology and in the pathophysiology of urinary dysfunction. Eur Urol 48:303-308
    • (2005) Eur Urol , vol.48 , pp. 303-308
    • Rapp, D.E.1    Lyon, M.B.2    Bales, G.T.3    Cook, S.P.4
  • 111
    • 0038024241 scopus 로고    scopus 로고
    • Rocks: Multifunctional kinases in cell behaviour
    • Riento K, Ridley AJ (2003) Rocks: multifunctional kinases in cell behaviour. Nat Rev Mol Cell Biol 4:446-456
    • (2003) Nat Rev Mol Cell Biol , vol.4 , pp. 446-456
    • Riento, K.1    Ridley, A.J.2
  • 112
    • 33748555532 scopus 로고    scopus 로고
    • 2+ release in the muscarinic-mediated contraction of mammalian urinary bladder smooth muscle
    • 2+ release in the muscarinic-mediated contraction of mammalian urinary bladder smooth muscle. BJU Int 98:868-875
    • (2006) BJU Int , vol.98 , pp. 868-875
    • Rivera, L.1    Brading, A.F.2
  • 113
    • 0034892851 scopus 로고    scopus 로고
    • 2 adrenoceptor-mediated vasoconstriction in porcine palmar lateral vein
    • 2 adrenoceptor-mediated vasoconstriction in porcine palmar lateral vein. Br J Pharmacol 133:859-866
    • (2001) Br J Pharmacol , vol.133 , pp. 859-866
    • Roberts, R.E.1
  • 117
    • 2442708970 scopus 로고    scopus 로고
    • Signal transduction underlying carbachol-induced contraction of human urinary bladder
    • Schneider T, Fetscher C, Krege S, Michel MC (2004a) Signal transduction underlying carbachol-induced contraction of human urinary bladder. J Pharmacol Exp Ther 309:1148-1153
    • (2004) J Pharmacol Exp Ther , vol.309 , pp. 1148-1153
    • Schneider, T.1    Fetscher, C.2    Krege, S.3    Michel, M.C.4
  • 119
    • 18744387418 scopus 로고    scopus 로고
    • A role for muscarinic receptors or rho-kinase in hypertension associated rat bladder dysfunction?
    • Schneider T, Hein P, Bai J, Michel MC (2005) A role for muscarinic receptors or rho-kinase in hypertension associated rat bladder dysfunction? J Urol 173:2178-2181
    • (2005) J Urol , vol.173 , pp. 2178-2181
    • Schneider, T.1    Hein, P.2    Bai, J.3    Michel, M.C.4
  • 122
    • 0029666437 scopus 로고    scopus 로고
    • 2+ mobilization from stores expressing inositol 1,4,5-trisphosphate receptors and ryanodine receptors in cerebellar granule neurones
    • 2+ mobilization from stores expressing inositol 1,4,5-trisphosphate receptors and ryanodine receptors in cerebellar granule neurones. J Neurochem 67:364-373
    • (1996) J Neurochem , vol.67 , pp. 364-373
    • Simpson, P.B.1    Nahorski, S.R.2    Challiss, R.A.3
  • 123
    • 0141751697 scopus 로고    scopus 로고
    • 2+ sensitivity of smooth muscle and nonmuscle myosin II: Modulated by G proteins, kinases, and myosin phosphatase
    • 2+ sensitivity of smooth muscle and nonmuscle myosin II: modulated by G proteins, kinases, and myosin phosphatase. Physiol Rev 83:1325-1358
    • (2003) Physiol Rev , vol.83 , pp. 1325-1358
    • Somlyo, A.P.1    Somlyo, A.V.2
  • 124
    • 21144434279 scopus 로고    scopus 로고
    • ROK-induced cross-link formation stiffens passive muscle: Reversible strain-induced stress softening in rabbit detrusor
    • Speich JE, Borgsmiller L, Call C, Mohr R, Ratz PH (2005) ROK-induced cross-link formation stiffens passive muscle: reversible strain-induced stress softening in rabbit detrusor. Am J Physiol 289:C12-C21
    • (2005) Am J Physiol , vol.289
    • Speich, J.E.1    Borgsmiller, L.2    Call, C.3    Mohr, R.4    Ratz, P.H.5
  • 126
    • 0025786794 scopus 로고
    • Effects of charybdotoxin and iberiotoxin on the spontaneous motility and tonus of different guinea pig smooth muscle tissues
    • Suarez-Kurtz G, Garcia ML, Kaczorowski GJ (1991) Effects of charybdotoxin and iberiotoxin on the spontaneous motility and tonus of different guinea pig smooth muscle tissues. J Pharmacol Exp Ther 259:439-443
    • (1991) J Pharmacol Exp Ther , vol.259 , pp. 439-443
    • Suarez-Kurtz, G.1    Garcia, M.L.2    Kaczorowski, G.J.3
  • 129
    • 0033949333 scopus 로고    scopus 로고
    • Tyrosine kinase-dependent calcium signaling in airway smooth muscle cells
    • Tolloczko B, Tao FC, Zacour ME, Martin JG (2000) Tyrosine kinase-dependent calcium signaling in airway smooth muscle cells. Am J Physiol 278:L1138-L1145
    • (2000) Am J Physiol , vol.278
    • Tolloczko, B.1    Tao, F.C.2    Zacour, M.E.3    Martin, J.G.4
  • 130
    • 0036083662 scopus 로고    scopus 로고
    • Src modulates serotonin-induced calcium signaling by regulating phosphatidylinositol 4,5-bisphosphate
    • Tolloczko B, Turkewitsch P, Choudry S, Bisotto S, Fixman ED, Martin JG (2002) Src modulates serotonin-induced calcium signaling by regulating phosphatidylinositol 4,5-bisphosphate. Am J Physiol 282:L1305-L1313
    • (2002) Am J Physiol , vol.282
    • Tolloczko, B.1    Turkewitsch, P.2    Choudry, S.3    Bisotto, S.4    Fixman, E.D.5    Martin, J.G.6
  • 131
    • 0028915824 scopus 로고
    • Effects of tyrosine kinase inhibitors on the contractility of rat mesenteric resistance arteries
    • Toma C, Jensen PE, Prieto D, Hughes A, Mulvany MJ, Aalkjaer C (1995) Effects of tyrosine kinase inhibitors on the contractility of rat mesenteric resistance arteries. Br J Pharmacol 114:1266-1272
    • (1995) Br J Pharmacol , vol.114 , pp. 1266-1272
    • Toma, C.1    Jensen, P.E.2    Prieto, D.3    Hughes, A.4    Mulvany, M.J.5    Aalkjaer, C.6
  • 135
    • 23644445651 scopus 로고    scopus 로고
    • Involvement of cyclic AMP-dependent and -independent mechanisms in the relaxation of rat detrusor muscle via β-adrenoceptors
    • Uchida H, Shishido K, Nomiya M, Yamaguchi O (2005) Involvement of cyclic AMP-dependent and -independent mechanisms in the relaxation of rat detrusor muscle via β-adrenoceptors. Eur J Pharmacol 518:195-202
    • (2005) Eur J Pharmacol , vol.518 , pp. 195-202
    • Uchida, H.1    Shishido, K.2    Nomiya, M.3    Yamaguchi, O.4
  • 138
    • 0033830128 scopus 로고    scopus 로고
    • Simultaneous recording of mechanical and intracellular electrical activity in guinea-pig urinary bladder smooth muscle: A comparison with human detrusor contraction
    • Visser AJ, van Mastrigt R (2000) Simultaneous recording of mechanical and intracellular electrical activity in guinea-pig urinary bladder smooth muscle: a comparison with human detrusor contraction. Urology 56:696-701
    • (2000) Urology , vol.56 , pp. 696-701
    • Visser, A.J.1    Van Mastrigt, R.2
  • 139
    • 0030789364 scopus 로고    scopus 로고
    • ERK activation and cellular proliferation in response to muscarinic acetylcholine receptor agonists
    • Wang P, Dhanasekaran N, Luthin GR (1997) ERK activation and cellular proliferation in response to muscarinic acetylcholine receptor agonists. Ann N Y Acad Sci 812:182-183
    • (1997) Ann N Y Acad Sci , vol.812 , pp. 182-183
    • Wang, P.1    Dhanasekaran, N.2    Luthin, G.R.3
  • 141
    • 0032160078 scopus 로고    scopus 로고
    • Dissociation of angiotensin II-stimulated activation of mitogen-activated protein kinase kinase from vascular contraction
    • Watts SW, Florian JA, Monroe KM (1998) Dissociation of angiotensin II-stimulated activation of mitogen-activated protein kinase kinase from vascular contraction. J Pharmacol Exp Ther 286:1431-1438
    • (1998) J Pharmacol Exp Ther , vol.286 , pp. 1431-1438
    • Watts, S.W.1    Florian, J.A.2    Monroe, K.M.3
  • 143
    • 25444523217 scopus 로고    scopus 로고
    • Bladder instillation of Escherichia coli lipopolysaccharide alters the muscle contractions in rat urinary bladder via a protein kinase C-related pathway
    • Weng TI, Chen WJ, Liu SH (2005) Bladder instillation of Escherichia coli lipopolysaccharide alters the muscle contractions in rat urinary bladder via a protein kinase C-related pathway. Toxicol Appl Pharmacol 208:163-169
    • (2005) Toxicol Appl Pharmacol , vol.208 , pp. 163-169
    • Weng, T.I.1    Chen, W.J.2    Liu, S.H.3
  • 144
    • 33845420077 scopus 로고    scopus 로고
    • Uropathogenic Escherichia coli alters muscle contractions in rat urinary bladder via a nitric oxide synthase-related signaling pathway
    • Weng TI, Chen WJ, Wu HY, Liu SH (2006) Uropathogenic Escherichia coli alters muscle contractions in rat urinary bladder via a nitric oxide synthase-related signaling pathway. J Infect Dis 194:1774-1782
    • (2006) J Infect Dis , vol.194 , pp. 1774-1782
    • Weng, T.I.1    Chen, W.J.2    Wu, H.Y.3    Liu, S.H.4
  • 145
    • 0037352327 scopus 로고    scopus 로고
    • Expression and functional role of Rho-kinase in rat urinary bladder smooth muscle
    • Wibberley A, Chen Z, Hu E, Hieble JP, Westfall TD (2003) Expression and functional role of Rho-kinase in rat urinary bladder smooth muscle. Br J Pharmacol 138:757-766
    • (2003) Br J Pharmacol , vol.138 , pp. 757-766
    • Wibberley, A.1    Chen, Z.2    Hu, E.3    Hieble, J.P.4    Westfall, T.D.5
  • 146
    • 0034105359 scopus 로고    scopus 로고
    • Effects of protein tyrosine kinase inhibitors on voltage-operated calcium channel currents in vascular smooth muscle cells and pp60(c-src) kinase activity
    • Wijetunge S, Lymn JS, Hughes AD (2000) Effects of protein tyrosine kinase inhibitors on voltage-operated calcium channel currents in vascular smooth muscle cells and pp60(c-src) kinase activity. Br J Pharmacol 129:1347-1354
    • (2000) Br J Pharmacol , vol.129 , pp. 1347-1354
    • Wijetunge, S.1    Lymn, J.S.2    Hughes, A.D.3
  • 147
    • 0034742117 scopus 로고    scopus 로고
    • 3-adrenergic receptor agonist CL-316243 on experimental bladder hyperreflexia and detrusor instability in the rat
    • 3-adrenergic receptor agonist CL-316243 on experimental bladder hyperreflexia and detrusor instability in the rat. J Urol 166:1142-1147
    • (2001) J Urol , vol.166 , pp. 1142-1147
    • Woods, M.1    Carson, N.2    Norton, N.W.3    Sheldon, J.H.4    Argentieri, T.M.5
  • 148
    • 0037206832 scopus 로고    scopus 로고
    • Dual regulation of voltage-gated calcium channels by PtdIns(4,5)P2
    • Wu L, Bauer CS, Zhen XG, Xie C, Yang J (2002) Dual regulation of voltage-gated calcium channels by PtdIns(4,5)P2. Nature 419:947-952
    • (2002) Nature , vol.419 , pp. 947-952
    • Wu, L.1    Bauer, C.S.2    Zhen, X.G.3    Xie, C.4    Yang, J.5
  • 152
    • 0036086110 scopus 로고    scopus 로고
    • ERK MAP kinases regulate smooth muscle contraction in ovine uterine artery: Effect of pregnancy
    • Xiao D, Zhang L (2002) ERK MAP kinases regulate smooth muscle contraction in ovine uterine artery: effect of pregnancy. Am J Physiol 282:H292-H300
    • (2002) Am J Physiol , vol.282
    • Xiao, D.1    Zhang, L.2
  • 153
    • 0033956825 scopus 로고    scopus 로고
    • The mechanism of contraction by 2-chloroadenosine in cat detrusor muscle cells
    • Yang SJ, An JY, Shim JO, Park CH, Huh IH, Sohn UD (2000) The mechanism of contraction by 2-chloroadenosine in cat detrusor muscle cells. J Urol 163:652-658
    • (2000) J Urol , vol.163 , pp. 652-658
    • Yang, S.J.1    An, J.Y.2    Shim, J.O.3    Park, C.H.4    Huh, I.H.5    Sohn, U.D.6
  • 154
    • 0028981963 scopus 로고
    • 2+ current in smooth muscle cells of the guinea-pig urinary bladder
    • 2+ current in smooth muscle cells of the guinea-pig urinary bladder. Exp Physiol 80:575-587
    • (1995) Exp Physiol , vol.80 , pp. 575-587
    • Yoshino, M.1    Yabu, H.2
  • 155
    • 33847174231 scopus 로고    scopus 로고
    • 2+-induced, Rho- and Rho kinase-dependent regulation of myosin phosphatase and contraction in isolated vascular smooth muscle cells
    • 2+-induced, Rho- and Rho kinase-dependent regulation of myosin phosphatase and contraction in isolated vascular smooth muscle cells. Mol Pharmacol 71:912-920
    • (2007) Mol Pharmacol , vol.71 , pp. 912-920
    • Yoshioka, K.1    Sugimoto, N.2    Takuwa, N.3    Takuwa, Y.4
  • 157
    • 0026713866 scopus 로고
    • + channel modulators on detrusor and portal vein strips from guinea pigs
    • + channel modulators on detrusor and portal vein strips from guinea pigs. Pharmacology 45:216-230
    • (1992) Pharmacology , vol.45 , pp. 216-230
    • Zografos, P.1    Li, J.H.2    Kau, S.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.